Danio rerio

17 known processes

ppargc1al

peroxisome proliferator-activated receptor gamma, coactivator 1 alpha like

(Aliases: PGC-1,PGC-1alpha,gb:dq017637,PGC1)

ppargc1al biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
heart developmentGO:00075073130.733
cellular component movementGO:00069283350.672
response to chemicalGO:00422213200.606
ameboidal type cell migrationGO:00016671430.553
aromatic compound biosynthetic processGO:00194382170.536
larval developmentGO:000216420.503
adult behaviorGO:003053420.396
regulation of biological qualityGO:00650082630.377
regulation of primary metabolic processGO:00800903110.363
homeostatic processGO:00425921420.304
cellular component morphogenesisGO:00329893360.288
embryonic organ morphogenesisGO:00485622740.274
heterocycle metabolic processGO:00464832900.272
heterocycle biosynthetic processGO:00181302150.269
localization of cellGO:00516742440.256
agingGO:000756820.252
nucleobase containing compound biosynthetic processGO:00346542050.249
negative regulation of biological processGO:00485193040.246
regulation of establishment of protein localizationGO:007020140.238
organic cyclic compound metabolic processGO:19013603010.235
cell migrationGO:00164772370.223
cellular nitrogen compound metabolic processGO:00346412900.220
regulation of multicellular organismal processGO:00512392770.214
striated muscle contractionGO:0006941120.214
generation of neuronsGO:00486993850.210
embryonic organ developmentGO:00485683810.210
nucleoside phosphate metabolic processGO:0006753280.208
response to organic cyclic compoundGO:0014070510.207
biosynthetic processGO:00090582940.205
regulation of metabolic processGO:00192223590.199
cytokinesisGO:000091030.195
regulation of cellular metabolic processGO:00313233200.195
muscle system processGO:0003012200.189
regulation of nitrogen compound metabolic processGO:00511712510.188
cell motilityGO:00488702440.187
purine nucleoside monophosphate catabolic processGO:000912840.180
digestive system developmentGO:00551232890.180
cellular biosynthetic processGO:00442492860.174
nitrogen compound metabolic processGO:00068073190.173
regulation of nucleobase containing compound metabolic processGO:00192192500.172
regulation of biosynthetic processGO:00098892500.169
nucleoside monophosphate catabolic processGO:000912540.169
tube morphogenesisGO:00352393490.168
response to drugGO:004249330.163
response to lipidGO:0033993600.162
regulation of metal ion transportGO:001095940.159
organic substance biosynthetic processGO:19015762890.156
nucleic acid templated transcriptionGO:00976591810.155
regulation of ion transmembrane transporter activityGO:003241220.154
oocyte anterior posterior axis specificationGO:000731440.142
locomotionGO:00400113130.142
atp catabolic processGO:000620040.142
regulation of nucleic acid templated transcriptionGO:19035062130.141
purine nucleotide metabolic processGO:0006163270.137
cation homeostasisGO:0055080330.133
organic cyclic compound biosynthetic processGO:19013622230.132
cellular aromatic compound metabolic processGO:00067252950.131
regulation of macromolecule metabolic processGO:00602553170.130
skeletal system developmentGO:00015011810.129
regulation of cell shapeGO:000836010.129
regulation of transmembrane transportGO:0034762180.125
regulation of gene expressionGO:00104682650.124
response to steroid hormoneGO:0048545350.124
organonitrogen compound metabolic processGO:1901564740.120
actin filament based movementGO:003004810.118
nucleobase containing compound metabolic processGO:00061392740.117
response to oxygen containing compoundGO:1901700550.116
response to endogenous stimulusGO:0009719830.116
monovalent inorganic cation homeostasisGO:005506790.113
cell projection organizationGO:00300302840.111
regulation of cellular biosynthetic processGO:00313262450.110
maintenance of locationGO:005123540.109
developmental growthGO:00485891660.108
cellular nitrogen compound biosynthetic processGO:00442712180.107
ion homeostasisGO:0050801410.106
establishment of localizationGO:00512342440.105
response to organic substanceGO:00100331530.104
embryo development ending in birth or egg hatchingGO:00097922710.099
rna biosynthetic processGO:00327741810.097
cellular response to steroid hormone stimulusGO:0071383310.097
ribonucleoside monophosphate catabolic processGO:000915840.095
regulation of cellular macromolecule biosynthetic processGO:20001122220.094
cell migration involved in gastrulationGO:0042074790.092
purine ribonucleotide metabolic processGO:0009150270.092
neuron developmentGO:00486662620.092
response to hormoneGO:0009725480.091
muscle structure developmentGO:00610611960.089
regulation of transmembrane transporter activityGO:002289820.089
negative regulation of cellular processGO:00485232830.089
cell cycle g1 s phase transitionGO:004484310.088
nuclear importGO:005117030.088
cellular macromolecule metabolic processGO:00442603910.087
regulation of transcription dna templatedGO:00063552130.085
cytoskeleton dependent cytokinesisGO:006164030.084
sensory organ developmentGO:00074233930.083
cellular response to organic substanceGO:00713101050.083
transcription from rna polymerase ii promoterGO:0006366800.083
cellular response to endogenous stimulusGO:0071495680.080
regulation of rna biosynthetic processGO:20011412130.079
regulation of protein transportGO:005122330.079
g1 s transition of mitotic cell cycleGO:000008210.079
digestive tract developmentGO:00485652650.076
regulation of blood pressureGO:000821710.076
stem cell differentiationGO:00488631170.076
cellular response to chemical stimulusGO:00708871570.075
cognitionGO:005089010.074
cell fate commitmentGO:0045165990.074
regulation of signal transductionGO:00099662250.072
mitotic cell cycleGO:0000278640.072
potassium ion transportGO:0006813100.071
transmembrane transportGO:00550851200.069
regulation of multicellular organism growthGO:004001440.069
calcium ion homeostasisGO:0055074190.068
cell cycleGO:0007049930.068
organelle assemblyGO:00709251100.068
cell morphogenesis involved in neuron differentiationGO:00486671630.067
purine containing compound metabolic processGO:0072521290.067
taxisGO:00423301090.066
ras protein signal transductionGO:000726570.065
small molecule metabolic processGO:0044281770.065
cell morphogenesis involved in differentiationGO:00009041950.064
divalent inorganic cation homeostasisGO:0072507220.064
positive regulation of biological processGO:00485182530.063
neuron differentiationGO:00301823530.061
response to estrogenGO:0043627270.061
protein localization to nucleusGO:003450430.061
circadian sleep wake cycle processGO:002241020.060
gene expressionGO:00104672520.060
regulation of intracellular protein transportGO:003315730.059
cardiac muscle tissue developmentGO:0048738480.059
cell projection morphogenesisGO:00488582440.059
digestive tract morphogenesisGO:00485462310.058
regulation of bindingGO:005109830.058
single organism transportGO:00447652060.058
actin mediated cell contractionGO:007025210.055
regulation of macromolecule biosynthetic processGO:00105562250.055
muscle contractionGO:0006936180.055
chemical homeostasisGO:0048878490.055
regulation of striated muscle contractionGO:000694220.055
protein stabilizationGO:005082120.054
ribonucleotide metabolic processGO:0009259270.054
regulation of rna metabolic processGO:00512522240.054
muscle cell differentiationGO:00426921390.054
regulation of muscle contractionGO:000693730.054
positive regulation of transportGO:005105020.054
cellular response to lipidGO:0071396390.053
signal transductionGO:00071654550.052
membrane fusionGO:006102520.052
transcription dna templatedGO:00063511810.052
regulation of protein targetingGO:190353320.051
synaptic growth at neuromuscular junctionGO:005112420.051
heart processGO:0003015710.051
macromolecule biosynthetic processGO:00090592270.050
cytokinetic processGO:003250620.049
regulation of transporter activityGO:003240920.048
apical junction assemblyGO:004329710.048
protein targeting to nucleusGO:004474430.048
ear developmentGO:00435831270.048
cellular ion homeostasisGO:0006873170.048
blood vessel developmentGO:00015682460.048
positive regulation of cell cycleGO:004578730.047
phosphate containing compound metabolic processGO:00067961080.047
negative regulation of cellular biosynthetic processGO:0031327550.047
negative regulation of protein transportGO:005122430.046
actin filament based processGO:0030029640.046
blood circulationGO:0008015870.046
metal ion transportGO:0030001580.046
intracellular estrogen receptor signaling pathwayGO:003052030.046
carbohydrate derivative metabolic processGO:1901135610.045
regulation of nucleoside metabolic processGO:000911820.045
heart morphogenesisGO:00030071560.045
regulation of calcium ion transportGO:005192420.045
establishment of protein localization to organelleGO:007259440.045
response to stressGO:00069502630.044
otic vesicle developmentGO:0071599420.044
response to alcoholGO:0097305140.044
tissue migrationGO:0090130370.043
cellular response to organic cyclic compoundGO:0071407380.043
negative regulation of macromolecule metabolic processGO:0010605760.043
metal ion homeostasisGO:0055065260.042
angiogenesisGO:00015251580.042
maternal determination of anterior posterior axis embryoGO:000835840.042
cellular sodium ion homeostasisGO:000688310.042
purine ribonucleoside monophosphate catabolic processGO:000916940.042
cellular metal ion homeostasisGO:0006875160.041
ventricular cardiac muscle tissue developmentGO:000322930.041
glucocorticoid metabolic processGO:000821120.041
regulation of blood circulationGO:1903522320.041
inorganic ion transmembrane transportGO:0098660570.040
cellular component assemblyGO:00226071700.040
regulation of cellular component organizationGO:0051128860.040
regulation of localizationGO:00328791040.040
calcium ion transportGO:0006816180.040
cell morphogenesisGO:00009022890.040
transportGO:00068102200.039
regulation of phGO:000688530.039
positive regulation of nitrogen compound metabolic processGO:0051173690.039
cellular macromolecule biosynthetic processGO:00346452240.039
sexual reproductionGO:0019953360.038
inorganic cation transmembrane transportGO:0098662500.038
regulation of anatomical structure morphogenesisGO:00226031300.038
regulation of circadian rhythmGO:004275240.038
nucleic acid metabolic processGO:00903042440.037
protein localization to plasma membraneGO:007265910.037
regulation of protein import into nucleusGO:004230620.036
organic substance catabolic processGO:1901575280.036
regulation of protein localization to nucleusGO:190018020.035
cellular monovalent inorganic cation homeostasisGO:003000420.035
rna metabolic processGO:00160702190.035
regulation of transportGO:0051049450.035
regulation of dendrite developmentGO:005077330.035
cellular homeostasisGO:0019725260.035
response to external stimulusGO:00096052640.035
organic substance transportGO:0071702580.034
chordate embryonic developmentGO:00430092710.034
positive regulation of macromolecule metabolic processGO:0010604930.034
regulation of developmental processGO:00507932470.034
cellular ketone metabolic processGO:0042180110.034
phosphorus metabolic processGO:00067931090.034
regulation of cytoplasmic transportGO:190364940.034
epithelial cell migrationGO:0010631250.034
ion transportGO:00068111140.034
exocrine system developmentGO:0035272280.034
regulation of protein complex assemblyGO:004325430.034
single organism reproductive processGO:0044702400.033
nucleobase containing small molecule metabolic processGO:0055086320.033
cellular response to extracellular stimulusGO:003166820.033
negative regulation of cytokine productionGO:000181810.033
regulation of dendrite morphogenesisGO:004881430.033
cell part morphogenesisGO:00329902460.032
response to glucocorticoidGO:005138410.032
multi organism processGO:00517041340.032
circulatory system processGO:0003013870.032
epithelial cell differentiationGO:00308551160.032
protein importGO:001703830.032
potassium ion transmembrane transportGO:0071805100.032
response to xenobiotic stimulusGO:0009410450.031
negative regulation of heart contractionGO:004582220.031
muscle organ developmentGO:00075171010.031
steroid hormone mediated signaling pathwayGO:004340190.031
regulation of purine nucleotide catabolic processGO:003312120.030
regulation of dna replicationGO:000627530.030
heart contractionGO:0060047710.030
rna localizationGO:000640340.030
nucleocytoplasmic transportGO:000691340.030
cellular response to hormone stimulusGO:0032870390.030
single organism organelle organizationGO:19025891990.030
guanosine containing compound catabolic processGO:190106920.029
ventricular cardiac muscle tissue morphogenesisGO:005501020.029
pole plasm assemblyGO:000731540.029
positive regulation of cytosolic calcium ion concentrationGO:000720440.029
regulation of protein polymerizationGO:003227120.029
cellular component biogenesisGO:00440851780.029
gamete generationGO:0007276330.029
regulation of transcription from rna polymerase ii promoterGO:00063571140.028
single organism nuclear importGO:190259330.028
regulation of system processGO:0044057400.028
regulation of cellular ketone metabolic processGO:001056570.028
positive regulation of cellular amine metabolic processGO:003324000.028
cellular calcium ion homeostasisGO:0006874130.028
nuclear transportGO:005116940.028
positive regulation of gtp catabolic processGO:003312610.028
striated muscle tissue developmentGO:00147061100.028
regulation of actin filament based movementGO:190311510.027
regulation of protein complex disassemblyGO:004324410.027
cellular response to nutrient levelsGO:003166920.027
single organism biosynthetic processGO:0044711710.027
cytoplasm organizationGO:000702840.027
protein polymerizationGO:005125840.027
system processGO:00030081850.027
positive regulation of metabolic processGO:00098931080.027
growthGO:00400071740.027
response to biotic stimulusGO:0009607970.027
neuroblast differentiationGO:001401610.027
blood vessel morphogenesisGO:00485142160.026
multicellular organism growthGO:003526440.026
regulation of cellular amino acid metabolic processGO:000652100.026
pectoral fin developmentGO:0033339500.026
macromolecule localizationGO:0033036540.026
otolith formationGO:003247520.026
epithelial tube morphogenesisGO:00605621480.026
positive regulation of cellular metabolic processGO:0031325940.026
axon developmentGO:00615641660.026
brain developmentGO:00074202930.026
antimicrobial humoral responseGO:001973020.026
cellular amine metabolic processGO:004410620.025
muscle cell developmentGO:00550011150.025
regulation of response to stimulusGO:00485832690.025
gtp metabolic processGO:004603940.025
ion transmembrane transportGO:0034220910.025
morphogenesis of an epitheliumGO:00020093330.025
amine metabolic processGO:000930820.025
skeletal muscle organ developmentGO:0060538780.025
regulation of multicellular organismal developmentGO:20000262230.025
muscle tissue developmentGO:00605371100.025
post golgi vesicle mediated transportGO:000689210.024
cellular response to external stimulusGO:007149620.024
regulation of membrane potentialGO:0042391230.024
regulation of cell communicationGO:00106462320.024
negative regulation of blood circulationGO:190352320.024
neuron projection morphogenesisGO:00488121610.024
membrane organizationGO:0061024210.024
monovalent inorganic cation transportGO:0015672420.024
regulation of cellular component movementGO:0051270550.024
regulation of circadian sleep wake cycleGO:004274910.023
lamellipodium assemblyGO:003003210.023
regulation of ion transmembrane transportGO:0034765180.023
regulation of cell projection organizationGO:0031344440.023
cellular component assembly involved in morphogenesisGO:00109271070.023
positive regulation of gene expressionGO:0010628710.023
axon ensheathment in central nervous systemGO:003229120.023
intracellular mrna localizationGO:000829810.023
single organism localizationGO:19025782250.023
multicellular organismal response to stressGO:003355520.023
hemopoiesisGO:00300971830.023
myofibril assemblyGO:0030239480.023
organophosphate biosynthetic processGO:0090407230.022
organophosphate metabolic processGO:0019637370.022
protein localizationGO:0008104400.022
establishment of protein localization to plasma membraneGO:009000210.022
intracellular receptor signaling pathwayGO:0030522300.022
cartilage developmentGO:0051216960.022
muscle cell cellular homeostasisGO:004671650.022
eye developmentGO:00016542770.021
positive regulation of cellular processGO:00485222010.021
pigmentationGO:0043473850.021
cell fate specificationGO:0001708680.021
actin filament polymerizationGO:003004120.021
post embryonic organ developmentGO:004856940.021
regulation of circadian sleep wake cycle sleepGO:004518710.021
sodium ion importGO:009736930.021
regulation of ion transportGO:0043269220.020
regulation of cytoskeleton organizationGO:0051493110.020
pigment cell differentiationGO:0050931380.020
phagocytosis engulfmentGO:000691110.020
striated muscle cell developmentGO:00550021080.020
energy homeostasisGO:009700930.020
vasculature developmentGO:00019442780.020
mitochondrion organizationGO:000700540.020
response to ketoneGO:190165410.020
cellular component disassemblyGO:002241110.020
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.020
ribose phosphate biosynthetic processGO:0046390200.020
single organism membrane fusionGO:004480120.019
ribonucleoside metabolic processGO:0009119110.019
negative regulation of cytoplasmic transportGO:190365020.019
carboxylic acid metabolic processGO:0019752220.019
multicellular organismal reproductive processGO:0048609350.019
endothelial cell migrationGO:0043542190.019
response to alkaloidGO:004327920.019
organelle organizationGO:00069962270.019
regulation of cellular amine metabolic processGO:003323800.019
protein import into nucleusGO:000660630.019
lipid storageGO:001991510.019
organic cyclic compound catabolic processGO:1901361150.019
positive regulation of catabolic processGO:000989640.018
specification of axis polarityGO:006500140.018
organic acid metabolic processGO:0006082310.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
sleepGO:003043110.018
cell migration involved in heart developmentGO:0060973220.018
catabolic processGO:0009056320.018
positive regulation of biosynthetic processGO:0009891680.018
appendage developmentGO:0048736800.018
negative regulation of metabolic processGO:0009892860.018
nucleoside catabolic processGO:000916470.018
small gtpase mediated signal transductionGO:000726480.018
negative regulation of cellular metabolic processGO:0031324770.018
lipid homeostasisGO:005508830.018
oocyte constructionGO:000730850.018
notochord developmentGO:0030903540.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
cell agingGO:000756920.017
regulation of signalingGO:00230512350.017
otolith developmentGO:0048840320.017
microglia differentiationGO:001400410.017
single organism cellular localizationGO:1902580460.017
regulation of systemic arterial blood pressureGO:000307310.017
regulation of establishment of protein localization to plasma membraneGO:009000310.017
posterior lateral line system developmentGO:0048915460.017
response to abiotic stimulusGO:00096281220.017
cellular aldehyde metabolic processGO:000608140.017
negative regulation of biosynthetic processGO:0009890550.017
cardiac muscle cell developmentGO:0055013200.017
startle responseGO:000196440.016
negative regulation of organelle organizationGO:001063940.016
action potentialGO:0001508190.016
protein complex disassemblyGO:004324110.016
extracellular matrix organizationGO:0030198270.016
cellular cation homeostasisGO:0030003170.016
lipid oxidationGO:003444010.016
regulation of cell substrate adhesionGO:001081010.016
cell surface receptor signaling pathwayGO:00071663250.016
proximal distal pattern formationGO:000995410.016
long chain fatty acid transportGO:001590910.016
positive regulation of apoptotic signaling pathwayGO:200123510.016
regulation of growthGO:0040008420.016
regulation of phosphorus metabolic processGO:0051174430.016
behaviorGO:0007610740.016
response to foodGO:003209410.016
inner ear developmentGO:00488391260.016
gastrulationGO:00073692080.016
oocyte developmentGO:0048599140.015
lipid catabolic processGO:001604240.015
regulation of neuron projection developmentGO:0010975400.015
negative regulation of nucleobase containing compound metabolic processGO:0045934590.015
embryonic skeletal system morphogenesisGO:0048704930.015
gtp catabolic processGO:000618420.015
cellular nitrogen compound catabolic processGO:0044270150.015
fin developmentGO:0033333770.015
regulation of heart growthGO:006042020.015
regulation of heart contractionGO:0008016320.015
regulation of cell morphogenesisGO:0022604420.015
cellular response to starvationGO:000926710.015
sodium ion homeostasisGO:005507830.015
heart loopingGO:0001947940.015
regulation of molecular functionGO:0065009700.015
cardiac muscle cell contractionGO:008600310.015
positive regulation of nucleobase containing compound metabolic processGO:0045935690.015
positive regulation of nucleic acid templated transcriptionGO:1903508570.014
posterior lateral line neuromast primordium migrationGO:0048920120.014
negative regulation of nucleocytoplasmic transportGO:004682320.014
central nervous system developmentGO:00074173870.014
regulation of protein bindingGO:004339330.014
protein depolymerizationGO:005126110.014
rhythmic processGO:0048511210.014
sensory perception of smellGO:000760820.014
specification of organ axis polarityGO:001008420.014
muscle cell fate determinationGO:000752110.014
divalent metal ion transportGO:0070838200.014
positive regulation of cyclic nucleotide metabolic processGO:003080180.014
negative regulation of apoptotic processGO:0043066550.014
synaptic target recognitionGO:000803910.014
neuron projection guidanceGO:0097485860.014
glycosyl compound metabolic processGO:1901657110.014
cell migration involved in heart formationGO:0060974100.014
divalent inorganic cation transportGO:0072511210.014
cation transportGO:0006812810.014
circadian sleep wake cycle sleepGO:005080210.014
regulation of nucleocytoplasmic transportGO:004682220.014
response to nutrientGO:000758430.014
ph reductionGO:004585110.014
regulation of synaptic plasticityGO:004816710.014
hormone metabolic processGO:0042445190.014
nucleoside metabolic processGO:0009116110.013
regulation of angiogenesisGO:0045765260.013
microtubule polymerization or depolymerizationGO:003110930.013
somatic muscle developmentGO:000752540.013
atp metabolic processGO:004603450.013
response to extracellular stimulusGO:0009991100.013
organonitrogen compound biosynthetic processGO:1901566470.013
positive regulation of camp metabolic processGO:003081620.013
blood vessel endothelial cell migrationGO:0043534180.013
endocrine system developmentGO:0035270650.013
skin developmentGO:0043588540.013
regulation of camp metabolic processGO:003081490.013
cardiac atrium developmentGO:000323040.013
energy reserve metabolic processGO:000611220.013
positive regulation of cellular catabolic processGO:003133130.013
macromolecular complex disassemblyGO:003298410.013
extracellular structure organizationGO:0043062270.013
regulation of rho protein signal transductionGO:003502320.013
skeletal system morphogenesisGO:00487051020.013
biological adhesionGO:0022610400.013
pancreas developmentGO:0031016840.013
regulation of protein depolymerizationGO:190187910.013
embryonic heart tube developmentGO:00350501330.013
regulation of cell motilityGO:2000145460.013
intracellular steroid hormone receptor signaling pathwayGO:003051850.013
negative regulation of cell deathGO:0060548600.013
single organism behaviorGO:0044708240.012
locomotor rhythmGO:004547530.012
cellular catabolic processGO:0044248270.012
negative regulation of dna metabolic processGO:005105340.012
axonogenesisGO:00074091520.012
negative regulation of programmed cell deathGO:0043069580.012
cell cycle arrestGO:000705010.012
guanosine containing compound metabolic processGO:190106840.012
hormone mediated signaling pathwayGO:000975590.012
embryonic cranial skeleton morphogenesisGO:0048701900.012
regulation of cardiac muscle contractionGO:005511720.012
nucleobase containing compound catabolic processGO:0034655150.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
oxoacid metabolic processGO:0043436310.012
retinoic acid receptor signaling pathwayGO:0048384160.012
oxidation reduction processGO:0055114410.012
aromatic compound catabolic processGO:0019439150.012

ppargc1al disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.152
musculoskeletal system diseaseDOID:1700.042
muscular diseaseDOID:008000000.025
muscle tissue diseaseDOID:6600.025
charcot marie tooth diseaseDOID:1059500.012
nervous system diseaseDOID:86300.012
neuropathyDOID:87000.012
neuromuscular diseaseDOID:44000.012