Danio rerio

29 known processes

col1a1a

collagen, type I, alpha 1a

(Aliases: sb:cb21,cb21,wu:fb02c06,sb:cb384,alpha1(I),col1a1,wu:fa99c12)

col1a1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to amino acidGO:004320020.999
Mouse
collagen biosynthetic processGO:003296420.987
Human
skeletal system developmentGO:00015011810.984
Human Zebrafish Mouse
cartilage developmentGO:0051216960.971
Zebrafish Mouse
collagen fibril organizationGO:003019910.961
Human
cartilage morphogenesisGO:0060536130.947
Zebrafish
appendage developmentGO:0048736800.946
wound healingGO:0042060900.930
notochord developmentGO:0030903540.921
Zebrafish
response to woundingGO:00096111160.915
fin developmentGO:0033333770.913
blood vessel developmentGO:00015682460.909
Human Mouse
developmental growthGO:00485891660.908
collagen metabolic processGO:003296320.902
Human
connective tissue developmentGO:0061448990.890
Zebrafish Mouse
pectoral fin developmentGO:0033339500.866
response to chemicalGO:00422213200.856
Mouse Rat
extracellular matrix constituent secretionGO:007027830.850
response to external stimulusGO:00096052640.820
Zebrafish Mouse Rat
regenerationGO:0031099910.803
fin morphogenesisGO:0033334530.784
negative regulation of cellular processGO:00485232830.767
Mouse
response to abiotic stimulusGO:00096281220.719
Zebrafish Mouse Rat
fin regenerationGO:0031101510.714
response to vitaminGO:003327330.689
Rat
tissue regenerationGO:0042246740.680
macromolecule biosynthetic processGO:00090592270.665
Human
extracellular structure organizationGO:0043062270.665
Human
regulation of ossificationGO:003027850.655
transportGO:00068102200.653
Mouse
embryonic organ developmentGO:00485683810.596
Zebrafish
osteoblast differentiationGO:000164950.577
Mouse
response to corticosteroidGO:003196010.550
Rat
negative regulation of multicellular organismal processGO:0051241690.550
direct ossificationGO:003607230.548
Mouse
medial fin morphogenesisGO:0035141140.533
appendage morphogenesisGO:0035107560.528
sensory organ morphogenesisGO:00905962000.512
cellular nitrogen compound biosynthetic processGO:00442712180.491
Human
negative regulation of biological processGO:00485193040.446
Mouse
response to stressGO:00069502630.437
single organism metabolic processGO:00447102170.429
Human
chondrocyte developmentGO:000206340.421
growthGO:00400071740.399
heterocycle biosynthetic processGO:00181302150.394
Human
ossificationGO:0001503230.388
angiogenesisGO:00015251580.369
extracellular matrix organizationGO:0030198270.366
Human
vasculature developmentGO:00019442780.364
Human Mouse
response to acid chemicalGO:0001101170.359
Mouse Rat
positive regulation of apoptotic processGO:0043065290.346
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.336
muscle organ developmentGO:00075171010.332
cellular response to growth factor stimulusGO:0071363390.331
Rat
proteoglycan metabolic processGO:0006029140.328
cell motilityGO:00488702440.316
Human
cellular response to retinoic acidGO:007130010.314
Rat
cellular macromolecule metabolic processGO:00442603910.312
Human
multicellular organismal metabolic processGO:004423620.308
Human
regulation of chondrocyte differentiationGO:003233010.304
positive regulation of canonical wnt signaling pathwayGO:009026340.293
Human
medial fin developmentGO:0033338160.290
regulation of multicellular organismal processGO:00512392770.287
regulation of signalingGO:00230512350.279
Human
localization of cellGO:00516742440.277
Human
heart morphogenesisGO:00030071560.271
blood vessel morphogenesisGO:00485142160.266
skin morphogenesisGO:004358970.264
Human
canonical wnt signaling pathwayGO:0060070480.248
Human
regulation of nucleobase containing compound metabolic processGO:00192192500.247
Human
negative regulation of protein maturationGO:1903318100.241
cellular component movementGO:00069283350.241
Human
nitrogen compound metabolic processGO:00068073190.236
Human
outflow tract morphogenesisGO:000315110.231
cell substrate adhesionGO:003158940.227
Mouse
response to oxygen containing compoundGO:1901700550.213
Mouse Rat
intramembranous ossificationGO:000195730.212
Mouse
multicellular organismal macromolecule metabolic processGO:004425920.206
Human
skeletal system morphogenesisGO:00487051020.205
Mouse
regulation of transcription dna templatedGO:00063552130.202
Human
visual perceptionGO:0007601170.202
Human
organic anion transportGO:0015711150.191
chondroitin sulfate metabolic processGO:003020420.189
caudal fin developmentGO:003333690.181
regulation of locomotionGO:0040012550.176
Human
negative regulation of developmental processGO:0051093650.174
morphogenesis of an epitheliumGO:00020093330.172
digestive system developmentGO:00551232890.171
homeostatic processGO:00425921420.169
establishment of localizationGO:00512342440.166
Mouse
embryonic skeletal system developmentGO:0048706970.161
Human
embryonic organ morphogenesisGO:00485622740.160
axonal defasciculationGO:000741420.158
positive regulation of response to stimulusGO:0048584800.153
Human
regulation of stem cell differentiationGO:200073640.150
Human
regulation of epithelial cell proliferationGO:005067830.149
negative regulation of protein processingGO:0010955100.149
regulation of cell differentiationGO:00455951420.149
Human
positive regulation of signalingGO:0023056560.143
Human
positive regulation of cell motilityGO:2000147110.143
Human
response to alcoholGO:0097305140.142
Rat
regulation of response to stimulusGO:00485832690.140
Human
regulation of gene expressionGO:00104682650.137
Human
cellular component morphogenesisGO:00329893360.137
Human
striated muscle tissue developmentGO:00147061100.135
response to lipidGO:0033993600.132
Rat
sensory organ developmentGO:00074233930.132
regulation of cellular metabolic processGO:00313233200.131
Human
cell migrationGO:00164772370.128
Human
organic substance biosynthetic processGO:19015762890.128
Human
nucleobase containing compound metabolic processGO:00061392740.126
Human
ion transportGO:00068111140.126
skin developmentGO:0043588540.124
Human Mouse
developmental growth involved in morphogenesisGO:0060560860.123
renal absorptionGO:007029310.123
regulation of ventricular cardiac muscle cell membrane repolarizationGO:006030710.122
regulation of cell substrate adhesionGO:001081010.120
Mouse
mesoderm formationGO:0001707430.119
protein heterooligomerizationGO:005129110.119
Mouse
embryonic limb morphogenesisGO:003032620.118
protein localization to nucleusGO:003450430.118
Human
aromatic compound biosynthetic processGO:00194382170.117
Human
response to inorganic substanceGO:0010035380.116
Rat
agingGO:000756820.114
single organism localizationGO:19025782250.113
bone morphogenesisGO:0060349110.111
Mouse
multicellular organism growthGO:003526440.109
regulation of canonical wnt signaling pathwayGO:0060828340.109
Human
protein metabolic processGO:00195381830.108
biological adhesionGO:0022610400.108
Mouse
regulation of endothelial cell proliferationGO:000193610.108
regulation of bindingGO:005109830.103
small molecule metabolic processGO:0044281770.102
regulation of multicellular organism growthGO:004001440.102
cellular response to oxygen containing compoundGO:1901701200.101
Mouse Rat
positive regulation of developmental processGO:0051094500.096
Human
locomotionGO:00400113130.096
Human
face morphogenesisGO:006032560.094
Mouse
negative regulation of response to stimulusGO:00485851040.089
regulation of nitrogen compound metabolic processGO:00511712510.087
Human
positive regulation of cellular biosynthetic processGO:0031328680.086
Human
endocardial cushion formationGO:000327220.086
sprouting angiogenesisGO:0002040530.085
positive regulation of cell communicationGO:0010647560.084
Human
skeletal muscle organ developmentGO:0060538780.083
regulation of wnt signaling pathwayGO:0030111530.081
Human
chemotaxisGO:00069351040.081
embryonic medial fin morphogenesisGO:003512260.080
regulation of proteolysisGO:0030162240.079
mesoderm developmentGO:0007498880.078
gene expressionGO:00104672520.077
Human
positive regulation of signal transductionGO:0009967560.077
Human
regulation of protein maturationGO:1903317100.077
eye morphogenesisGO:00485921440.076
regulation of protein modification by small protein conjugation or removalGO:190332030.073
regulation of endodermal cell differentiationGO:1903224150.073
regulation of signal transductionGO:00099662250.072
Human
positive regulation of cellular processGO:00485222010.071
Human
rna metabolic processGO:00160702190.071
Human
single organismal cell cell adhesionGO:0016337290.070
oxoacid metabolic processGO:0043436310.070
small gtpase mediated signal transductionGO:000726480.069
negative regulation of signal transductionGO:0009968940.069
caudal fin morphogenesisGO:003514370.068
anion transportGO:0006820380.067
sensory perception of light stimulusGO:0050953190.066
Human
regulation of extrinsic apoptotic signaling pathwayGO:200123630.065
growth plate cartilage developmentGO:000341720.065
eye developmentGO:00016542770.063
embryo development ending in birth or egg hatchingGO:00097922710.063
Human
nucleic acid templated transcriptionGO:00976591810.062
Human
response to bacteriumGO:0009617580.062
regulation of macromolecule biosynthetic processGO:00105562250.061
Human
basement membrane assemblyGO:007083130.060
neuron developmentGO:00486662620.060
negative regulation of epithelial cell proliferationGO:005068010.060
negative regulation of gene expressionGO:0010629650.060
endocardial cushion developmentGO:000319760.059
neurological system processGO:0050877620.058
Human
response to nutrient levelsGO:0031667100.057
Rat
cellular response to external stimulusGO:007149620.057
Mouse Rat
muscle structure developmentGO:00610611960.056
cellular response to fibroblast growth factor stimulusGO:0044344220.055
Rat
positive regulation of stress activated mapk cascadeGO:003287430.055
regulation of cell proliferationGO:0042127370.055
response to mechanical stimulusGO:0009612240.054
Zebrafish Mouse Rat
release of sequestered calcium ion into cytosolGO:005120930.054
cranial suture morphogenesisGO:006036310.053
head developmentGO:00603223030.052
Mouse
epithelial to mesenchymal transitionGO:0001837210.052
Human
response to growth factorGO:0070848390.052
Rat
mucopolysaccharide metabolic processGO:190351020.051
signal transductionGO:00071654550.051
Human
digestive tract developmentGO:00485652650.051
single organism transportGO:00447652060.051
single organism cell adhesionGO:0098602290.050
response to nutrientGO:000758430.050
Rat
regulation of dna replicationGO:000627530.050
regulation of cellular component movementGO:0051270550.050
Human
cellular protein modification processGO:00064641000.049
response to organic substanceGO:00100331530.049
Mouse Rat
nucleobase containing compound biosynthetic processGO:00346542050.049
Human
response to retinoic acidGO:003252660.048
Rat
response to organic cyclic compoundGO:0014070510.048
Rat
regulation of cytokine productionGO:000181730.047
organic substance transportGO:0071702580.046
Mouse
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.046
cellular component biogenesisGO:00440851780.046
Mouse
heart developmentGO:00075073130.046
negative regulation of proteolysisGO:0045861100.045
rna biosynthetic processGO:00327741810.045
Human
organic cyclic compound biosynthetic processGO:19013622230.045
Human
immune system developmentGO:00025201910.045
response to drugGO:004249330.044
Rat
regulation of nucleic acid templated transcriptionGO:19035062130.044
Human
ras protein signal transductionGO:000726570.044
cellular response to chemical stimulusGO:00708871570.044
Mouse Rat
protein importGO:001703830.043
cartilage development involved in endochondral bone morphogenesisGO:006035180.043
Mouse
rho protein signal transductionGO:000726650.043
positive regulation of cell adhesionGO:004578510.043
regulation of cell motilityGO:2000145460.043
Human
regulation of rna biosynthetic processGO:20011412130.043
Human
heterocycle metabolic processGO:00464832900.043
Human
hatchingGO:003518840.042
dorsal ventral pattern formationGO:00099531250.042
symbiosis encompassing mutualism through parasitismGO:004440340.042
ameboidal type cell migrationGO:00016671430.042
cell surface receptor signaling pathwayGO:00071663250.041
Human
proteolysisGO:0006508380.040
bmp signaling pathwayGO:0030509520.040
positive regulation of cell substrate adhesionGO:001081110.039
regulation of developmental growthGO:0048638380.039
endodermal cell differentiationGO:0035987190.039
multicellular organismal water homeostasisGO:005089110.039
organic cyclic compound metabolic processGO:19013603010.039
Human
cellular aromatic compound metabolic processGO:00067252950.038
Human
stem cell proliferationGO:007208940.038
sensory perceptionGO:0007600390.038
Human
sensory perception of mechanical stimulusGO:0050954160.037
Human
gastrulationGO:00073692080.037
endochondral bone morphogenesisGO:006035080.037
Mouse
cellular macromolecule biosynthetic processGO:00346452240.037
Human
positive regulation of cell differentiationGO:0045597300.037
Human
proteolysis involved in cellular protein catabolic processGO:005160330.037
single organism reproductive processGO:0044702400.036
cartilage condensationGO:000150230.036
cell proliferationGO:0008283800.036
regulation of anatomical structure morphogenesisGO:00226031300.036
Human
regulation of establishment of protein localizationGO:007020140.036
limb bud formationGO:006017420.036
bone developmentGO:0060348140.035
Mouse
ear morphogenesisGO:0042471640.035
phagocytosisGO:000690930.034
cellular protein catabolic processGO:004425740.034
regionalizationGO:00030022740.034
muscle cell developmentGO:00550011150.033
regulation of biological qualityGO:00650082630.033
regulation of cell communicationGO:00106462320.033
Human
nuclear importGO:005117030.033
response to biotic stimulusGO:0009607970.033
organism emergence from protective structureGO:007168440.033
regulation of cartilage developmentGO:006103570.033
regulation of cell migrationGO:0030334400.032
Human
formation of primary germ layerGO:0001704620.032
negative regulation of mitosisGO:004583930.032
cellular response to lipidGO:0071396390.032
Rat
response to transforming growth factor betaGO:007155970.031
Rat
macromolecular complex subunit organizationGO:0043933740.031
Human Mouse
body morphogenesisGO:0010171160.031
Mouse
cellular response to biotic stimulusGO:007121630.031
axonogenesisGO:00074091520.031
regulation of macromolecule metabolic processGO:00602553170.031
Human
regulation of cytoplasmic transportGO:190364940.030
multi organism processGO:00517041340.030
protein trimerizationGO:007020640.030
Mouse
limb developmentGO:006017380.030
negative regulation of macromolecule metabolic processGO:0010605760.029
taxisGO:00423301090.029
leukocyte homeostasisGO:000177620.029
transcription dna templatedGO:00063511810.029
Human
mesenchymal cell proliferationGO:001046310.029
embryonic skeletal system morphogenesisGO:0048704930.029
embryonic hemopoiesisGO:0035162530.028
epithelial cell proliferationGO:0050673170.028
regulation of epithelial to mesenchymal transitionGO:001071730.028
Human
hemostasisGO:0007599130.027
regulation of cellular macromolecule biosynthetic processGO:20001122220.027
Human
organic acid metabolic processGO:0006082310.026
tissue remodelingGO:004877140.026
response to oxygen levelsGO:0070482250.026
Rat
endothelial cell proliferationGO:0001935110.026
cellular response to organic substanceGO:00713101050.026
Mouse Rat
anion transmembrane transportGO:0098656120.026
regulation of hydrolase activityGO:0051336280.026
positive regulation of catabolic processGO:000989640.025
regulation of cell morphogenesisGO:0022604420.025
Human
long chain fatty acid transportGO:001590910.025
wnt signaling pathwayGO:0016055800.025
Human
response to external biotic stimulusGO:0043207970.024
response to nitrogen compoundGO:1901698190.024
Mouse Rat
positive regulation of molecular functionGO:0044093330.024
cellular response to extracellular stimulusGO:003166820.024
Rat
regulation of cellular biosynthetic processGO:00313262450.024
Human
positive regulation of locomotionGO:0040017140.024
Human
regulation of protein processingGO:0070613100.024
positive regulation of stem cell proliferationGO:200064810.024
glycoprotein metabolic processGO:0009100230.023
defense responseGO:0006952470.023
positive regulation of cell activationGO:005086710.023
positive regulation of immune system processGO:0002684170.023
negative regulation of cytokine productionGO:000181810.023
lipid catabolic processGO:001604240.023
cell projection morphogenesisGO:00488582440.023
protein maturationGO:0051604120.023
meiotic nuclear divisionGO:000712640.023
axon extensionGO:0048675450.022
cellular protein metabolic processGO:00442671290.022
response to endogenous stimulusGO:0009719830.022
Mouse Rat
hematopoietic or lymphoid organ developmentGO:00485341910.022
anatomical structure homeostasisGO:0060249360.022
extrinsic apoptotic signaling pathwayGO:009719130.022
divalent metal ion transportGO:0070838200.022
positive regulation of rna biosynthetic processGO:1902680570.022
Human
neuron projection morphogenesisGO:00488121610.022
system processGO:00030081850.021
Human
establishment of localization in cellGO:0051649770.021
cell matrix adhesionGO:000716040.021
embryonic viscerocranium morphogenesisGO:0048703520.021
biosynthetic processGO:00090582940.021
Human
axon developmentGO:00615641660.021
protein processingGO:0016485120.021
regulation of multicellular organismal developmentGO:20000262230.021
Human
regulation of protein ubiquitinationGO:003139630.021
cell growthGO:0016049570.021
regulation of biosynthetic processGO:00098892500.020
Human
cardiac atrium developmentGO:000323040.020
lens fiber cell developmentGO:007030730.020
positive regulation of lipid metabolic processGO:004583410.020
specification of symmetryGO:00097992040.020
tube morphogenesisGO:00352393490.020
cell morphogenesis involved in neuron differentiationGO:00486671630.019
cell adhesionGO:0007155400.019
Mouse
epithelial cell developmentGO:0002064420.019
regulation of developmental processGO:00507932470.019
Human
negative regulation of cell communicationGO:0010648960.018
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.018
convergent extensionGO:00600261180.018
cellular protein localizationGO:0034613200.018
Human
positive regulation of cell developmentGO:0010720250.018
Human
single organism nuclear importGO:190259330.018
regulation of localizationGO:00328791040.018
Human
cell morphogenesisGO:00009022890.018
Human
positive regulation of nucleic acid templated transcriptionGO:1903508570.018
Human
locomotory behaviorGO:0007626340.018
glycosaminoglycan metabolic processGO:003020390.018
muscle cell differentiationGO:00426921390.018
modulation by virus of host morphology or physiologyGO:001904810.018
response to lipopolysaccharideGO:0032496130.017
positive regulation of nitrogen compound metabolic processGO:0051173690.017
Human
positive regulation of mesenchymal cell proliferationGO:000205310.017
positive regulation of biological processGO:00485182530.017
Human
sensory perception of soundGO:000760590.016
Human
respiratory system developmentGO:006054150.016
carboxylic acid transportGO:004694280.016
digestive tract morphogenesisGO:00485462310.016
urogenital system developmentGO:0001655970.016
negative regulation of embryonic developmentGO:0045992110.016
eye photoreceptor cell differentiationGO:0001754450.016
response to cytokineGO:003409770.016
Rat
nuclear transportGO:005116940.016
response to steroid hormoneGO:0048545350.016
Rat
bone mineralizationGO:003028290.015
divalent inorganic anion homeostasisGO:007250550.015
regulation of multicellular organismal metabolic processGO:004424620.015
embryonic caudal fin morphogenesisGO:003512430.015
endocardial cushion morphogenesisGO:000320330.015
cellular nitrogen compound metabolic processGO:00346412900.014
Human
camera type eye morphogenesisGO:00485931080.014
regulation of collagen metabolic processGO:001071220.014
response to molecule of bacterial originGO:0002237140.014
regulation of mesenchymal cell proliferationGO:001046410.014
regulation of peptidase activityGO:0052547230.014
ribonucleoside biosynthetic processGO:004245520.014
negative regulation of cell developmentGO:0010721260.014
trabecula formationGO:006034320.014
Mouse
regulation of cysteine type endopeptidase activityGO:2000116210.013
positive regulation of cellular metabolic processGO:0031325940.013
Human
endoderm formationGO:0001706290.013
negative regulation of dna replicationGO:000815620.013
cellular response to nutrientGO:003167010.013
Rat
protein complex assemblyGO:0006461300.013
Mouse
establishment of protein localization to organelleGO:007259440.013
embryonic cranial skeleton morphogenesisGO:0048701900.013
regulation of nervous system developmentGO:0051960900.013
multicellular organismal homeostasisGO:0048871290.013
inner ear morphogenesisGO:0042472630.013
developmental process involved in reproductionGO:0003006270.013
negative regulation of cell differentiationGO:0045596460.013
glial cell fate determinationGO:000740310.013
regulation of primary metabolic processGO:00800903110.013
Human
cellular macromolecule localizationGO:0070727210.013
Human
modification of morphology or physiology of other organismGO:003582140.013
immune system processGO:00023762410.013
zymogen activationGO:003163830.012
protein acylationGO:004354330.012
cell deathGO:00082191210.012
tissue homeostasisGO:0001894250.012
response to organonitrogen compoundGO:0010243120.012
Mouse Rat
regulation of cellular protein catabolic processGO:190336210.012
determination of bilateral symmetryGO:00098552040.012
iron ion homeostasisGO:005507240.012
internal peptidyl lysine acetylationGO:001839320.012
craniofacial suture morphogenesisGO:009709420.012
negative regulation of cell adhesionGO:000716260.012
Mouse
regulation of bmp signaling pathwayGO:0030510390.012
regulation of cell cell adhesionGO:0022407130.012
response to hydrogen peroxideGO:004254230.012
Rat
ion transmembrane transportGO:0034220910.012
defense response to fungusGO:005083220.012
macromolecule modificationGO:00434121110.012
negative regulation of nuclear divisionGO:005178430.011
endomembrane system organizationGO:0010256130.011
metal ion transportGO:0030001580.011
protein import into nucleusGO:000660630.011
positive regulation of hydrolase activityGO:0051345130.011
chordate embryonic developmentGO:00430092710.011
Human
neuron projection developmentGO:00311751800.011
negative regulation of endodermal cell differentiationGO:190322580.011
regulation of stem cell proliferationGO:007209120.011
regulation of protein bindingGO:004339330.011
regulation of cell adhesionGO:0030155150.011
Mouse
regulation of protein import into nucleusGO:004230620.011
mesenchymal cell differentiationGO:0048762870.011
Human
mesodermal cell migrationGO:0008078120.011
cellular response to organic cyclic compoundGO:0071407380.011
Rat
regulation of synapse organizationGO:005080730.011
regulation of cell activationGO:005086510.010
regulation of body fluid levelsGO:0050878160.010
primary neural tube formationGO:001402010.010
carboxylic acid metabolic processGO:0019752220.010
positive regulation of epithelial cell proliferationGO:005067910.010
regulation of protein catabolic processGO:004217610.010
circulatory system processGO:0003013870.010
epidermis morphogenesisGO:004873040.010
carbohydrate derivative metabolic processGO:1901135610.010
positive regulation of epithelial cell migrationGO:001063420.010
protein modification processGO:00362111000.010
nucleocytoplasmic transportGO:000691340.010
fatty acid transportGO:001590810.010
regulation of sequestering of calcium ionGO:005128240.010
cytosolic calcium ion transportGO:006040130.010

col1a1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.980
Human
musculoskeletal system diseaseDOID:1700.980
Human
osteochondrodysplasiaDOID:225600.980
Human
bone diseaseDOID:008000100.980
Human
bone development diseaseDOID:008000600.980
Human
connective tissue diseaseDOID:6500.980
Human
bone remodeling diseaseDOID:008000500.855
Human
osteogenesis imperfectaDOID:1234700.692
Human
osteoporosisDOID:1147600.588
Human
bone resorption diseaseDOID:008001100.588
Human
synostosisDOID:1197100.059
dysostosisDOID:193400.059
nervous system diseaseDOID:86300.033
central nervous system diseaseDOID:33100.024
neurodegenerative diseaseDOID:128900.024