Danio rerio

0 known processes

styx

serine/threonine/tyrosine interacting protein

(Aliases: im:6908851,si:dkey-119m7.5,zgc:110621)

styx biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.081
cellular protein catabolic processGO:004425740.054
modification dependent protein catabolic processGO:001994130.045
nitrogen compound metabolic processGO:00068073190.043
agingGO:000756820.043
ubiquitin dependent protein catabolic processGO:000651130.043
maintenance of locationGO:005123540.043
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.041
organic substance biosynthetic processGO:19015762890.041
modification dependent macromolecule catabolic processGO:004363230.040
organic cyclic compound metabolic processGO:19013603010.039
signal transductionGO:00071654550.038
proteolysis involved in cellular protein catabolic processGO:005160330.038
multicellular organism growthGO:003526440.038
proteasomal protein catabolic processGO:001049820.038
nucleobase containing compound metabolic processGO:00061392740.038
establishment of protein localization to organelleGO:007259440.038
cellular nitrogen compound metabolic processGO:00346412900.037
cellular macromolecule metabolic processGO:00442603910.037
organic cyclic compound biosynthetic processGO:19013622230.036
positive regulation of transportGO:005105020.035
regulation of metabolic processGO:00192223590.034
nuclear transportGO:005116940.034
regulation of multicellular organism growthGO:004001440.033
nucleic acid metabolic processGO:00903042440.033
cellular biosynthetic processGO:00442492860.032
regulation of gene expressionGO:00104682650.032
rna metabolic processGO:00160702190.031
gene expressionGO:00104672520.031
heterocycle metabolic processGO:00464832900.031
aromatic compound biosynthetic processGO:00194382170.031
regulation of biosynthetic processGO:00098892500.031
cellular aromatic compound metabolic processGO:00067252950.031
response to stressGO:00069502630.030
regulation of establishment of protein localizationGO:007020140.029
biosynthetic processGO:00090582940.029
cellular nitrogen compound biosynthetic processGO:00442712180.029
nucleocytoplasmic transportGO:000691340.029
phagocytosisGO:000690930.029
regulation of protein transportGO:005122330.029
amine metabolic processGO:000930820.029
meiotic nuclear divisionGO:000712640.029
lipid storageGO:001991510.028
mitochondrion organizationGO:000700540.028
macromolecule biosynthetic processGO:00090592270.028
stem cell maintenanceGO:001982740.028
response to drugGO:004249330.028
cellular macromolecule biosynthetic processGO:00346452240.028
regulation of cytokine productionGO:000181730.028
regulation of protein complex assemblyGO:004325430.028
regulation of primary metabolic processGO:00800903110.027
protein localization to nucleusGO:003450430.027
regulation of nitrogen compound metabolic processGO:00511712510.027
single organism membrane fusionGO:004480120.027
heterocycle biosynthetic processGO:00181302150.027
positive regulation of cell cycleGO:004578730.027
cellular amine metabolic processGO:004410620.026
negative regulation of biological processGO:00485193040.026
nucleic acid templated transcriptionGO:00976591810.026
regulation of rna metabolic processGO:00512522240.026
regulation of protein catabolic processGO:004217610.026
membrane fusionGO:006102520.026
autophagyGO:000691440.026
regulation of macromolecule metabolic processGO:00602553170.026
immune system processGO:00023762410.026
regulation of cellular biosynthetic processGO:00313262450.026
cell surface receptor signaling pathwayGO:00071663250.026
regulation of cellular metabolic processGO:00313233200.026
regulation of protein localization to nucleusGO:190018020.026
organelle fusionGO:004828430.026
rna biosynthetic processGO:00327741810.025
protein importGO:001703830.025
positive regulation of catabolic processGO:000989640.025
negative regulation of protein phosphorylationGO:000193340.025
regulation of nucleocytoplasmic transportGO:004682220.025
nucleobase containing compound biosynthetic processGO:00346542050.025
protein import into nucleusGO:000660630.024
positive regulation of cellular component biogenesisGO:004408930.024
transcription dna templatedGO:00063511810.024
single organism metabolic processGO:00447102170.024
single organism nuclear importGO:190259330.023
rna localizationGO:000640340.023
regulation of cell activationGO:005086510.023
endosomal transportGO:001619720.023
regulation of cell shapeGO:000836010.023
cellular ketone metabolic processGO:0042180110.023
cytokinesisGO:000091030.023
regulation of protein import into nucleusGO:004230620.023
regulation of mrna processingGO:005068430.023
regulation of macromolecule biosynthetic processGO:00105562250.022
regulation of nucleobase containing compound metabolic processGO:00192192500.022
regulation of cellular macromolecule biosynthetic processGO:20001122220.022
regulation of cellular amine metabolic processGO:003323800.022
positive regulation of cellular processGO:00485222010.022
cellular response to external stimulusGO:007149620.022
response to chemicalGO:00422213200.021
regulation of mrna splicing via spliceosomeGO:004802430.021
cell cycle g1 s phase transitionGO:004484310.021
regulation of alternative mrna splicing via spliceosomeGO:000038110.021
nuclear importGO:005117030.021
regulation of protein modification by small protein conjugation or removalGO:190332030.021
regulation of intracellular protein transportGO:003315730.021
regulation of meiotic cell cycleGO:005144510.021
organelle organizationGO:00069962270.021
protein acetylationGO:000647320.021
regulation of cytoplasmic transportGO:190364940.021
sensory organ developmentGO:00074233930.021
guanosine containing compound metabolic processGO:190106840.021
organonitrogen compound metabolic processGO:1901564740.020
meiotic cell cycle processGO:190304630.020
negative regulation of cellular processGO:00485232830.020
regulation of multicellular organismal processGO:00512392770.020
protein localization to plasma membraneGO:007265910.020
regulation of transcription dna templatedGO:00063552130.020
regulation of nucleic acid templated transcriptionGO:19035062130.020
regulation of cellular amino acid metabolic processGO:000652100.020
positive regulation of translationGO:004572710.020
ribonucleoside monophosphate catabolic processGO:000915840.020
regulation of cell communicationGO:00106462320.020
small molecule metabolic processGO:0044281770.020
regulation of cellular ketone metabolic processGO:001056570.020
establishment of localizationGO:00512342440.020
peptidyl lysine acetylationGO:001839420.020
g1 s transition of mitotic cell cycleGO:000008210.019
internal protein amino acid acetylationGO:000647520.019
cellular response to biotic stimulusGO:007121630.019
phagocytosis engulfmentGO:000691110.019
cellular component disassemblyGO:002241110.019
protein targeting to nucleusGO:004474430.019
leukocyte proliferationGO:007066110.019
protein metabolic processGO:00195381830.019
cellular response to lipopolysaccharideGO:007122230.019
positive regulation of protein complex assemblyGO:003133420.019
regulation of protein ubiquitinationGO:003139630.019
regulation of signal transductionGO:00099662250.019
protein polymerizationGO:005125840.019
regulation of bindingGO:005109830.019
protein acylationGO:004354330.019
regulation of protein targetingGO:190353320.019
regulation of signalingGO:00230512350.019
carboxylic acid metabolic processGO:0019752220.019
cellular response to extracellular stimulusGO:003166820.019
transportGO:00068102200.019
internal peptidyl lysine acetylationGO:001839320.019
regulation of rna biosynthetic processGO:20011412130.018
cellular response to nutrient levelsGO:003166920.018
gtp metabolic processGO:004603940.018
positive regulation of cytokine productionGO:000181920.018
membrane invaginationGO:001032410.018
gtp catabolic processGO:000618420.018
cellular protein metabolic processGO:00442671290.018
negative regulation of catabolic processGO:000989530.018
nucleoside monophosphate catabolic processGO:000912540.018
response to uvGO:000941130.018
regulation of response to stimulusGO:00485832690.018
production of molecular mediator of immune responseGO:000244020.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.018
single organism organelle organizationGO:19025891990.018
eye developmentGO:00016542770.018
positive regulation of cellular catabolic processGO:003133130.018
extrinsic apoptotic signaling pathwayGO:009719130.018
guanosine containing compound catabolic processGO:190106920.018
response to topologically incorrect proteinGO:003596620.018
cellular response to chemical stimulusGO:00708871570.017
i kappab kinase nf kappab signalingGO:000724940.017
positive regulation of biological processGO:00485182530.017
mononuclear cell proliferationGO:003294310.017
protein secretionGO:000930610.017
cellular amino acid metabolic processGO:000652070.017
cellular response to molecule of bacterial originGO:007121930.017
development of primary female sexual characteristicsGO:004654540.017
oxoacid metabolic processGO:0043436310.017
regulation of erk1 and erk2 cascadeGO:007037240.017
purine ribonucleoside monophosphate catabolic processGO:000916940.017
b cell activationGO:004211320.017
regulation of synapse organizationGO:005080730.017
positive regulation of cell activationGO:005086710.017
cellular component biogenesisGO:00440851780.017
organic acid metabolic processGO:0006082310.017
erk1 and erk2 cascadeGO:007037140.016
protein dephosphorylationGO:000647030.016
protein polyubiquitinationGO:000020940.016
cellular response to starvationGO:000926710.016
regulation of neural precursor cell proliferationGO:200017730.016
central nervous system developmentGO:00074173870.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
positive regulation of cell adhesionGO:004578510.016
actin filament polymerizationGO:003004120.016
cellular component assemblyGO:00226071700.016
positive regulation of secretionGO:005104710.016
cellular respirationGO:004533330.016
meiotic chromosome segregationGO:004513230.016
regulation of autophagyGO:001050630.016
positive regulation of cellular amine metabolic processGO:003324000.016
regulation of biological qualityGO:00650082630.016
cognitionGO:005089010.016
locomotionGO:00400113130.016
cytoskeleton dependent cytokinesisGO:006164030.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
golgi vesicle transportGO:004819330.016
tissue remodelingGO:004877140.016
positive regulation of immune effector processGO:000269930.015
spermatid developmentGO:000728620.015
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.015
cellular component morphogenesisGO:00329893360.015
response to external stimulusGO:00096052640.015
spindle assemblyGO:005122520.015
negative regulation of protein kinase activityGO:000646940.015
negative regulation of kinase activityGO:003367340.015
regulation of reproductive processGO:200024140.015
locomotor rhythmGO:004547530.015
intracellular signal transductionGO:0035556850.015
mitochondrial transportGO:000683920.015
atp catabolic processGO:000620040.015
hemopoiesisGO:00300971830.015
microtubule organizing center organizationGO:003102310.015
synaptic growth at neuromuscular junctionGO:005112420.015
positive regulation of cytoskeleton organizationGO:005149530.015
positive regulation of stress activated mapk cascadeGO:003287430.015
camera type eye developmentGO:00430102220.015
localization of cellGO:00516742440.015
macromolecule modificationGO:00434121110.015
cellular component movementGO:00069283350.015
dna templated transcription elongationGO:000635430.015
purine nucleoside monophosphate catabolic processGO:000912840.015
lymphocyte proliferationGO:004665110.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
immune system developmentGO:00025201910.015
regulation of cellular protein catabolic processGO:190336210.015
antimicrobial humoral responseGO:001973020.015
peptide transportGO:001583310.015
rna modificationGO:000945120.014
protein complex disassemblyGO:004324110.014
regulation of circadian rhythmGO:004275240.014
interspecies interaction between organismsGO:004441940.014
regulation of multicellular organismal developmentGO:20000262230.014
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.014
centrosome organizationGO:005129710.014
cellular amide metabolic processGO:004360340.014
adult behaviorGO:003053420.014
negative regulation of protein transportGO:005122430.014
regulation of protein polymerizationGO:003227120.014
cell migrationGO:00164772370.014
single organism localizationGO:19025782250.014
positive regulation of dna metabolic processGO:005105410.014
regulation of synapse assemblyGO:005196330.014
compound eye developmentGO:004874920.014
negative regulation of protein localization to nucleusGO:190018120.014
negative regulation of metabolic processGO:0009892860.014
transcription from rna polymerase ii promoterGO:0006366800.014
exocytosisGO:000688710.014
growthGO:00400071740.014
macromolecular complex disassemblyGO:003298410.014
digestive system developmentGO:00551232890.014
protein stabilizationGO:005082120.014
positive regulation of myeloid cell differentiationGO:004563920.014
spermatid differentiationGO:004851520.013
system processGO:00030081850.013
cell part morphogenesisGO:00329902460.013
morphogenesis of an epitheliumGO:00020093330.013
embryo development ending in birth or egg hatchingGO:00097922710.013
cellular response to radiationGO:007147840.013
cell morphogenesisGO:00009022890.013
protein modification processGO:00362111000.013
secondary metabolic processGO:001974830.013
stem cell divisionGO:001714510.013
regulation of developmental processGO:00507932470.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
regulation of production of molecular mediator of immune responseGO:000270010.013
peptidyl serine modificationGO:001820920.013
double strand break repairGO:000630230.013
female sex differentiationGO:004666040.013
vasculature developmentGO:00019442780.013
cell matrix adhesionGO:000716040.013
neuron differentiationGO:00301823530.013
multi organism cellular processGO:004476420.013
stem cell proliferationGO:007208940.013
positive regulation of secretion by cellGO:190353210.013
cellular response to organic substanceGO:00713101050.013
regulation of purine nucleotide catabolic processGO:003312120.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
cellular response to light stimulusGO:007148240.013
tube morphogenesisGO:00352393490.013
specification of symmetryGO:00097992040.013
regulation of inflammatory responseGO:005072720.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
sequestering of calcium ionGO:005120830.012
regulation of dna templated transcription elongationGO:003278430.012
germ line stem cell maintenanceGO:003071820.012
cellular carbohydrate metabolic processGO:004426240.012
brain developmentGO:00074202930.012
regulation of synaptic plasticityGO:004816710.012
cell projection organizationGO:00300302840.012
mitotic dna damage checkpointGO:004477340.012
single organism transportGO:00447652060.012
centrosome cycleGO:000709810.012
regulation of nucleoside metabolic processGO:000911820.012
viral processGO:001603210.012
somatic stem cell maintenanceGO:003501910.012
positive regulation of jnk cascadeGO:004633030.012
response to biotic stimulusGO:0009607970.012
nucleobase containing compound transportGO:001593120.012
response to hexoseGO:000974630.012
response to organic substanceGO:00100331530.012
negative regulation of sequestering of calcium ionGO:005128340.012
developmental growthGO:00485891660.012
vacuolar transportGO:000703420.012
single fertilizationGO:000733830.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
peptidyl serine phosphorylationGO:001810510.012
mitotic dna integrity checkpointGO:004477440.012
response to external biotic stimulusGO:0043207970.012
negative regulation of mapk cascadeGO:004340940.012
adherens junction organizationGO:003433240.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
establishment of rna localizationGO:005123630.012
regulation of stem cell proliferationGO:007209120.012
nuclear exportGO:005116810.012
sequestering of metal ionGO:005123830.012
regulation of protein bindingGO:004339330.012
actin polymerization or depolymerizationGO:000815420.012
meiosis iGO:000712710.012
digestive tract morphogenesisGO:00485462310.012
regulation of response to biotic stimulusGO:000283120.012
response to monosaccharideGO:003428430.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
regulation of blood pressureGO:000821710.011
alternative mrna splicing via spliceosomeGO:000038010.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
response to carbohydrateGO:000974330.011
response to abiotic stimulusGO:00096281220.011
embryonic organ developmentGO:00485683810.011
digestive tract developmentGO:00485652650.011
regulation of organ growthGO:004662030.011
lamellipodium assemblyGO:003003210.011
rna export from nucleusGO:000640510.011
positive regulation of chromosome organizationGO:200125210.011
negative regulation of nuclear divisionGO:005178430.011
signal transduction in absence of ligandGO:003803410.011
negative regulation of cytokine productionGO:000181810.011
blood vessel developmentGO:00015682460.011
response to hydrogen peroxideGO:004254230.011
carbohydrate homeostasisGO:003350010.011
neuroblast proliferationGO:000740520.011
response to corticosteroidGO:003196010.011
regulation of jak stat cascadeGO:004642530.011
phosphorus metabolic processGO:00067931090.011
retina development in camera type eyeGO:00600411460.011
glial cell migrationGO:000834730.011
head developmentGO:00603223030.011
neuron developmentGO:00486662620.011
regulation of gtpase activityGO:004308720.011
regulation of stem cell differentiationGO:200073640.011
regulation of organelle assemblyGO:190211540.011
positive regulation of nucleotide catabolic processGO:003081310.011
cell substrate adhesionGO:003158940.011
cellular monovalent inorganic cation homeostasisGO:003000420.011
positive regulation of leukocyte differentiationGO:190210710.011
cellular response to topologically incorrect proteinGO:003596720.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
negative regulation of defense responseGO:003134820.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
positive regulation of multi organism processGO:004390230.011
positive regulation of gtp catabolic processGO:003312610.011
response to unfolded proteinGO:000698620.011
cellular response to stressGO:0033554620.011
positive regulation of metabolic processGO:00098931080.011
lipid homeostasisGO:005508830.011
cortical cytoskeleton organizationGO:003086510.011
fertilizationGO:000956630.011
transcription elongation from rna polymerase ii promoterGO:000636830.011
mitotic cytokinesisGO:000028130.011
cell projection morphogenesisGO:00488582440.011
cellular protein modification processGO:00064641000.011
cell cycleGO:0007049930.011
forebrain cell migrationGO:002188510.011
cell deathGO:00082191210.010
protein homooligomerizationGO:005126030.010
negative regulation of multi organism processGO:004390130.010
response to nutrientGO:000758430.010
regulation of chromosome segregationGO:005198310.010
regulation of nucleotide catabolic processGO:003081120.010
developmental programmed cell deathGO:001062340.010
regulation of microtubule cytoskeleton organizationGO:007050730.010
negative regulation of macromolecule metabolic processGO:0010605760.010
heart developmentGO:00075073130.010
gastrulationGO:00073692080.010
regionalizationGO:00030022740.010
regulation of cellular carbohydrate metabolic processGO:001067540.010
nucleic acid transportGO:005065720.010
phosphate containing compound metabolic processGO:00067961080.010
regulation of cell projection assemblyGO:006049140.010
organelle assemblyGO:00709251100.010
cytokinetic processGO:003250620.010
female gonad developmentGO:000858540.010
regulation of synaptic growth at neuromuscular junctionGO:000858210.010
positive regulation of canonical wnt signaling pathwayGO:009026340.010
negative regulation of intracellular transportGO:003238730.010
mitotic g2 m transition checkpointGO:004481830.010
regulation of programmed cell deathGO:00430671010.010
positive regulation of chromatin modificationGO:190331010.010
chemosensory behaviorGO:000763510.010

styx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.052
nervous system diseaseDOID:86300.025
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
organ system cancerDOID:005068600.015
disease of metabolismDOID:001466700.014
inherited metabolic disorderDOID:65500.014
musculoskeletal system diseaseDOID:1700.014
sensory system diseaseDOID:005015500.013
eye and adnexa diseaseDOID:149200.013
eye diseaseDOID:561400.011