Danio rerio

0 known processes

smc4

structural maintenance of chromosomes 4

(Aliases: fb99b10,smc4l1,cb788,wu:fb99b10,chunp6901)

smc4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of nuclear divisionGO:005178430.941
meiotic nuclear divisionGO:000712640.726
Mouse
larval developmentGO:000216420.723
Worm
sister chromatid segregationGO:000081960.638
Human Yeast Worm
chromosome organization involved in meiosisGO:007019210.591
Mouse
meiosis iGO:000712710.562
nucleic acid metabolic processGO:00903042440.509
Human Yeast Mouse
regulation of macromolecule metabolic processGO:00602553170.489
Worm
nitrogen compound metabolic processGO:00068073190.486
Human Yeast Mouse
regulation of primary metabolic processGO:00800903110.482
cellular macromolecule biosynthetic processGO:00346452240.475
Yeast
regulation of meiotic cell cycleGO:005144510.456
chromosome organizationGO:0051276310.455
Human Yeast Mouse Worm
regulation of gene expressionGO:00104682650.455
Worm
negative regulation of cell divisionGO:005178240.453
heterocycle metabolic processGO:00464832900.421
Human Yeast Mouse
microtubule based processGO:0007017600.410
nucleobase containing compound metabolic processGO:00061392740.378
Human Yeast Mouse
gene expressionGO:00104672520.377
Worm
mitotic sister chromatid segregationGO:000007060.373
Human Yeast Worm
negative regulation of cell cycle processGO:001094890.348
single organism localizationGO:19025782250.341
Yeast
regulation of cellular metabolic processGO:00313233200.339
negative regulation of chromosome organizationGO:200125110.298
mitotic cell cycleGO:0000278640.294
Human Yeast Worm
mitotic cell cycle processGO:1903047480.287
Human Yeast Worm
regulation of nitrogen compound metabolic processGO:00511712510.277
cellular macromolecule metabolic processGO:00442603910.276
Human Yeast Mouse
negative regulation of cellular processGO:00485232830.275
microtubule cytoskeleton organization involved in mitosisGO:190285010.275
single organism organelle organizationGO:19025891990.265
Human Yeast Mouse Worm
nuclear divisionGO:0000280230.250
Human Yeast Mouse Worm
meiotic cell cycle processGO:190304630.249
Mouse
response to stressGO:00069502630.241
positive regulation of biological processGO:00485182530.241
negative regulation of biological processGO:00485193040.235
cellular aromatic compound metabolic processGO:00067252950.222
Human Yeast Mouse
aromatic compound biosynthetic processGO:00194382170.209
embryo development ending in birth or egg hatchingGO:00097922710.204
Worm
negative regulation of macromolecule metabolic processGO:0010605760.203
cellular nitrogen compound metabolic processGO:00346412900.202
Human Yeast Mouse
regulation of macromolecule biosynthetic processGO:00105562250.202
modification dependent protein catabolic processGO:001994130.197
regulation of cellular biosynthetic processGO:00313262450.193
negative regulation of cellular component organizationGO:0051129160.184
meiotic chromosome segregationGO:004513230.182
Mouse
regulation of biological qualityGO:00650082630.173
maintenance of locationGO:005123540.173
single organism metabolic processGO:00447102170.173
Human Yeast Mouse
organic cyclic compound metabolic processGO:19013603010.171
Human Yeast Mouse
cytoskeleton organizationGO:0007010960.170
negative regulation of nucleobase containing compound metabolic processGO:0045934590.166
spindle assemblyGO:005122520.164
heterocycle biosynthetic processGO:00181302150.163
protein targeting to nucleusGO:004474430.163
regulation of nucleocytoplasmic transportGO:004682220.157
dna metabolic processGO:0006259270.156
Human Yeast Mouse
mitotic nuclear divisionGO:0007067180.155
Human Yeast Worm
positive regulation of metabolic processGO:00098931080.154
regulation of nucleobase containing compound metabolic processGO:00192192500.153
negative regulation of mitosisGO:004583930.152
protein complex subunit organizationGO:0071822460.151
Mouse
spindle organizationGO:000705150.147
rna metabolic processGO:00160702190.145
organelle fissionGO:0048285230.144
Human Yeast Mouse Worm
cellular protein catabolic processGO:004425740.143
mitotic sister chromatid cohesionGO:000706420.143
positive regulation of catabolic processGO:000989640.142
spindle assembly involved in mitosisGO:009030710.133
astral microtubule organizationGO:003095310.131
microtubule based movementGO:0007018330.130
proteolysis involved in cellular protein catabolic processGO:005160330.129
sister chromatid cohesionGO:000706220.129
organelle organizationGO:00069962270.128
Human Yeast Mouse Worm
male meiosisGO:000714020.127
negative regulation of cellular catabolic processGO:003133030.125
chromosome segregationGO:0007059120.119
Human Yeast Mouse Worm
cellular component biogenesisGO:00440851780.118
nucleic acid templated transcriptionGO:00976591810.118
biosynthetic processGO:00090582940.116
Yeast
cellular component movementGO:00069283350.114
Worm
nucleobase containing compound biosynthetic processGO:00346542050.113
localization of cellGO:00516742440.110
Worm
negative regulation of cellular metabolic processGO:0031324770.109
macromolecule biosynthetic processGO:00090592270.107
Yeast
microtubule cytoskeleton organizationGO:0000226330.102
developmental growthGO:00485891660.099
locomotionGO:00400113130.094
Worm
regulation of metabolic processGO:00192223590.093
Worm
camera type eye developmentGO:00430102220.090
establishment of localizationGO:00512342440.090
regulation of protein import into nucleusGO:004230620.089
negative regulation of cellular biosynthetic processGO:0031327550.089
single organism nuclear importGO:190259330.088
negative regulation of cell cycleGO:0045786140.087
mitotic spindle organizationGO:000705250.082
regulation of cell cycleGO:0051726520.081
regulation of biosynthetic processGO:00098892500.080
macromolecular complex subunit organizationGO:0043933740.079
Mouse
agingGO:000756820.079
cellular nitrogen compound biosynthetic processGO:00442712180.078
deathGO:00162651210.078
protein import into nucleusGO:000660630.077
regulation of protein transportGO:005122330.077
ribonucleoside monophosphate catabolic processGO:000915840.077
Yeast
negative regulation of macromolecule biosynthetic processGO:0010558480.076
regulation of establishment of protein localizationGO:007020140.075
multicellular organism growthGO:003526440.075
cellular component assemblyGO:00226071700.075
regulation of multicellular organism growthGO:004001440.075
cellular localizationGO:0051641970.074
Yeast
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.074
organic cyclic compound biosynthetic processGO:19013622230.072
regulation of rna biosynthetic processGO:20011412130.071
regulation of nuclear divisionGO:005178390.070
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.070
regulation of protein metabolic processGO:0051246560.069
mitotic metaphase plate congressionGO:000708010.069
eye developmentGO:00016542770.069
proteasomal protein catabolic processGO:001049820.067
chordate embryonic developmentGO:00430092710.067
signal transductionGO:00071654550.066
oocyte maturationGO:000155640.066
negative regulation of nitrogen compound metabolic processGO:0051172590.066
mitotic cell cycle phase transitionGO:004477290.065
macromolecular complex assemblyGO:0065003350.064
phosphorus metabolic processGO:00067931090.063
Yeast
production of molecular mediator of immune responseGO:000244020.063
retina development in camera type eyeGO:00600411460.063
negative regulation of metabolic processGO:0009892860.061
reproductionGO:0000003400.061
Mouse Worm
peptidyl serine modificationGO:001820920.061
positive regulation of macromolecule metabolic processGO:0010604930.061
negative regulation of mitotic cell cycle phase transitionGO:190199150.061
regulation of nucleic acid templated transcriptionGO:19035062130.061
stem cell maintenanceGO:001982740.060
negative regulation of catabolic processGO:000989530.060
atp catabolic processGO:000620040.059
Yeast
protein importGO:001703830.058
cell cycleGO:0007049930.058
Human Yeast Mouse Worm
homeostatic processGO:00425921420.057
regulation of intracellular protein transportGO:003315730.056
regulation of rna metabolic processGO:00512522240.056
nucleoside monophosphate catabolic processGO:000912540.054
Yeast
peptidyl serine phosphorylationGO:001810510.054
protein metabolic processGO:00195381830.053
rna biosynthetic processGO:00327741810.053
cellular biosynthetic processGO:00442492860.052
Yeast
immune system developmentGO:00025201910.052
organic substance biosynthetic processGO:19015762890.052
Yeast
regulation of organelle organizationGO:0033043290.052
cytokinetic processGO:003250620.052
negative regulation of cell cycle phase transitionGO:190198850.051
protein modification processGO:00362111000.051
double strand break repairGO:000630230.050
response to biotic stimulusGO:0009607970.049
establishment of protein localization to organelleGO:007259440.047
regulation of cytoplasmic transportGO:190364940.047
nucleocytoplasmic transportGO:000691340.047
positive regulation of cell cycleGO:004578730.046
positive regulation of cellular processGO:00485222010.046
meiosis iiGO:000713510.045
negative regulation of biosynthetic processGO:0009890550.045
macromolecule modificationGO:00434121110.045
regulation of cellular macromolecule biosynthetic processGO:20001122220.045
nuclear transportGO:005116940.044
cell cycle processGO:0022402530.044
Human Yeast Mouse Worm
cellular response to stressGO:0033554620.044
cell migrationGO:00164772370.044
Worm
centrosome organizationGO:005129710.043
transcription dna templatedGO:00063511810.043
regulation of cellular component organizationGO:0051128860.043
cell proliferationGO:0008283800.042
modification dependent macromolecule catabolic processGO:004363230.042
sensory organ developmentGO:00074233930.042
immune system processGO:00023762410.042
purine ribonucleoside monophosphate catabolic processGO:000916940.041
Yeast
phosphorylationGO:0016310690.041
regulation of organelle assemblyGO:190211540.041
apoptotic processGO:00069151160.041
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.040
regulation of protein catabolic processGO:004217610.040
organic substance catabolic processGO:1901575280.040
Yeast
protein localization to nucleusGO:003450430.039
regulation of gene expression epigeneticGO:0040029110.039
Worm
positive regulation of cellular metabolic processGO:0031325940.038
positive regulation of cellular catabolic processGO:003133130.038
reproductive processGO:0022414400.038
Worm
negative regulation of organelle organizationGO:001063940.038
regulation of transcription dna templatedGO:00063552130.037
negative regulation of mitotic cell cycleGO:0045930110.037
regulation of protein localization to nucleusGO:190018020.037
regulation of cellular protein metabolic processGO:0032268520.037
regulation of apoptotic processGO:0042981980.036
meiotic spindle organizationGO:000021210.036
nuclear importGO:005117030.036
programmed cell deathGO:00125011190.036
growthGO:00400071740.036
catabolic processGO:0009056320.035
Yeast
digestive system developmentGO:00551232890.035
single organism transportGO:00447652060.035
organelle assemblyGO:00709251100.035
regulation of transcription from rna polymerase ii promoterGO:00063571140.034
regulation of response to stimulusGO:00485832690.034
actin filament based processGO:0030029640.034
regulation of developmental processGO:00507932470.034
cell morphogenesisGO:00009022890.033
stem cell proliferationGO:007208940.033
regulation of protein targetingGO:190353320.033
cellular macromolecule catabolic processGO:0044265120.033
microtubule organizing center organizationGO:003102310.032
g2 dna damage checkpointGO:003157230.031
cell motilityGO:00488702440.031
Worm
regulation of cellular protein catabolic processGO:190336210.031
regenerationGO:0031099910.031
regulation of purine nucleotide catabolic processGO:003312120.030
lipid homeostasisGO:005508830.029
cellular response to chemical stimulusGO:00708871570.029
cellular catabolic processGO:0044248270.029
Yeast
cell fate commitmentGO:0045165990.028
negative regulation of protein import into nucleusGO:004230820.028
exocrine pancreas developmentGO:0031017280.028
centrosome cycleGO:000709810.028
regulation of multicellular organismal processGO:00512392770.028
regulation of cell cycle processGO:0010564200.027
regulation of heart growthGO:006042020.027
immunoglobulin mediated immune responseGO:001606430.027
negative regulation of cytoplasmic transportGO:190365020.027
protein phosphorylationGO:0006468470.027
regulation of cell communicationGO:00106462320.027
dna methylation on cytosineGO:003277630.027
negative regulation of gene expressionGO:0010629650.027
cellular component morphogenesisGO:00329893360.026
regulation of mitotic cell cycleGO:0007346250.026
peptidyl threonine modificationGO:001821010.026
transportGO:00068102200.026
regulation of programmed cell deathGO:00430671010.026
negative regulation of protein localization to nucleusGO:190018120.026
regulation of catalytic activityGO:0050790550.025
spindle assembly involved in meiosisGO:009030610.025
cellular protein modification processGO:00064641000.025
digestive tract developmentGO:00485652650.024
regulation of signalingGO:00230512350.024
ubiquitin dependent protein catabolic processGO:000651130.023
regulation of proteolysisGO:0030162240.023
phosphate containing compound metabolic processGO:00067961080.023
Yeast
nucleic acid phosphodiester bond hydrolysisGO:009030560.023
chromosome localizationGO:005000020.023
regulation of chromatin modificationGO:190330850.023
small molecule metabolic processGO:0044281770.022
Yeast
negative regulation of protein transportGO:005122430.022
negative regulation of nucleic acid templated transcriptionGO:1903507450.022
cell divisionGO:0051301200.022
hematopoietic or lymphoid organ developmentGO:00485341910.022
regulation of phosphorylationGO:0042325260.021
response to abiotic stimulusGO:00096281220.021
female meiotic divisionGO:000714320.021
positive regulation of nitrogen compound metabolic processGO:0051173690.021
positive regulation of cell activationGO:005086710.021
regulation of cell divisionGO:0051302120.021
negative regulation of meiotic cell cycleGO:005144710.021
regulation of cell differentiationGO:00455951420.021
female meiosis chromosome segregationGO:001632110.021
multi organism processGO:00517041340.021
Worm
protein complex assemblyGO:0006461300.020
negative regulation of nucleocytoplasmic transportGO:004682320.020
response to endogenous stimulusGO:0009719830.020
negative regulation of cell differentiationGO:0045596460.020
cell cycle g2 m phase transitionGO:004483940.020
dna biosynthetic processGO:007189730.020
guanosine containing compound metabolic processGO:190106840.020
purine nucleoside monophosphate catabolic processGO:000912840.020
Yeast
negative regulation of protein complex assemblyGO:003133310.019
g1 s transition of mitotic cell cycleGO:000008210.019
fin regenerationGO:0031101510.019
single organism reproductive processGO:0044702400.019
Worm
somatic cell dna recombinationGO:001644410.019
meiotic cell cycleGO:005132150.019
Mouse
cellular protein metabolic processGO:00442671290.019
cytokinesisGO:000091030.019
transcription from rna polymerase ii promoterGO:0006366800.019
response to organic substanceGO:00100331530.019
germ cell developmentGO:0007281220.019
negative regulation of histone modificationGO:003105710.019
regulation of chromosome segregationGO:005198310.018
small gtpase mediated signal transductionGO:000726480.018
mitotic cell cycle embryonicGO:004544820.018
regulation of phosphate metabolic processGO:0019220430.018
regulation of transportGO:0051049450.018
negative regulation of histone methylationGO:003106110.018
negative regulation of protein processingGO:0010955100.018
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.018
vesicle mediated transportGO:0016192220.018
reproductive system developmentGO:006145850.018
Worm
negative regulation of dna metabolic processGO:005105340.018
cell deathGO:00082191210.018
pyrimidine containing compound metabolic processGO:007252730.017
regulation of localizationGO:00328791040.017
negative regulation of apoptotic processGO:0043066550.017
mitotic g2 m transition checkpointGO:004481830.017
regulation of histone h3 k9 methylationGO:005157020.017
mitotic g2 dna damage checkpointGO:000709530.017
tissue regenerationGO:0042246740.017
intracellular signal transductionGO:0035556850.017
microtubule polymerizationGO:004678520.017
dna catabolic processGO:000630810.016
posttranscriptional regulation of gene expressionGO:0010608140.016
protein polymerizationGO:005125840.016
regulation of dna catabolic processGO:190362410.016
cell cycle arrestGO:000705010.016
regulation of nucleoside metabolic processGO:000911820.016
regulation of cell shapeGO:000836010.016
retina morphogenesis in camera type eyeGO:0060042790.016
phagocytosisGO:000690930.016
neural retina developmentGO:0003407490.016
response to uvGO:000941130.016
response to chemicalGO:00422213200.016
regulation of cell deathGO:00109411030.016
response to external stimulusGO:00096052640.016
regulation of cell cycle phase transitionGO:190198780.016
fertilizationGO:000956630.016
peptidyl threonine phosphorylationGO:001810710.015
cleavage furrow formationGO:003608920.015
positive regulation of cellular amine metabolic processGO:003324000.015
cilium morphogenesisGO:0060271850.015
regulation of protein complex assemblyGO:004325430.014
nitric oxide biosynthetic processGO:000680920.014
negative regulation of chromatin modificationGO:190330910.014
regulation of stem cell proliferationGO:007209120.014
carboxylic acid metabolic processGO:0019752220.014
cellular component disassemblyGO:002241110.014
mitotic cell cycle checkpointGO:000709350.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
organonitrogen compound metabolic processGO:1901564740.014
Yeast
cellular response to organic substanceGO:00713101050.014
negative regulation of cell deathGO:0060548600.013
establishment of localization in cellGO:0051649770.013
response to external biotic stimulusGO:0043207970.013
cellular macromolecular complex assemblyGO:0034622240.013
proteolysisGO:0006508380.013
centrosome duplicationGO:005129810.013
gland developmentGO:00487321430.013
regulation of nucleotide catabolic processGO:003081120.013
regulation of reproductive processGO:200024140.013
positive regulation of protein metabolic processGO:0051247230.013
response to other organismGO:0051707970.013
negative regulation of rna biosynthetic processGO:1902679450.013
regulation of bindingGO:005109830.013
cell substrate junction assemblyGO:000704420.013
negative regulation of developmental processGO:0051093650.012
organic substance transportGO:0071702580.012
response to amino acidGO:004320020.012
g2 m transition of mitotic cell cycleGO:000008640.012
regulation of molecular functionGO:0065009700.012
protein complex biogenesisGO:0070271300.012
single organism biosynthetic processGO:0044711710.012
photoreceptor cell differentiationGO:0046530550.012
myeloid cell homeostasisGO:0002262560.012
regulation of mitosisGO:000708890.012
actin cytoskeleton organizationGO:0030036630.012
neuron developmentGO:00486662620.012
Worm
response to drugGO:004249330.012
regulation of intracellular signal transductionGO:1902531570.011
cytoskeleton dependent cytokinesisGO:006164030.011
positive regulation of chromatin modificationGO:190331010.011
regulation of cell proliferationGO:0042127370.011
positive regulation of transportGO:005105020.011
cellular response to endogenous stimulusGO:0071495680.011
protein localizationGO:0008104400.011
positive regulation of catalytic activityGO:0043085250.011
regulation of cellular amino acid metabolic processGO:000652100.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
cell part morphogenesisGO:00329902460.011
regulation of protein processingGO:0070613100.011
oxoacid metabolic processGO:0043436310.011
embryonic skeletal system developmentGO:0048706970.011
pharyngeal system developmentGO:0060037180.011
pyrimidine containing compound biosynthetic processGO:007252820.011
cellular component assembly involved in morphogenesisGO:00109271070.011
gtp catabolic processGO:000618420.011
regulation of histone methylationGO:003106030.011
regulation of protein bindingGO:004339330.011
mitotic dna damage checkpointGO:004477340.010
mitotic dna integrity checkpointGO:004477440.010
heart developmentGO:00075073130.010
embryonic skeletal joint developmentGO:007249830.010
hatchingGO:003518840.010
hepaticobiliary system developmentGO:0061008980.010
negative regulation of intracellular protein transportGO:009031730.010
cell substrate adhesionGO:003158940.010

smc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.028
disease of cellular proliferationDOID:1456600.028
cancerDOID:16200.028
gastrointestinal system cancerDOID:311900.028
large intestine cancerDOID:567200.021
intestinal cancerDOID:1015500.021
nervous system diseaseDOID:86300.013
disease of anatomical entityDOID:700.013
colorectal cancerDOID:925600.013
colon cancerDOID:21900.011
colon carcinomaDOID:152000.011