Danio rerio

102 known processes

cdk5

cyclin-dependent protein kinase 5

(Aliases: zgc:101604)

cdk5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
signal transductionGO:00071654550.139
Mouse Fly
regulation of synaptic growth at neuromuscular junctionGO:000858210.113
Fly
cognitionGO:005089010.104
Mouse
central nervous system developmentGO:00074173870.092
regulation of developmental processGO:00507932470.086
Mouse Fly
negative regulation of cellular processGO:00485232830.082
regulation of metabolic processGO:00192223590.079
Human Mouse
vasculature developmentGO:00019442780.076
head developmentGO:00603223030.072
Mouse
heterocycle metabolic processGO:00464832900.072
Human
stem cell proliferationGO:007208940.071
positive regulation of transportGO:005105020.063
Mouse
regulation of multicellular organismal developmentGO:20000262230.062
Mouse Fly
regulation of synaptic plasticityGO:004816710.061
Mouse Rat
nitrogen compound metabolic processGO:00068073190.060
Human
regulation of signalingGO:00230512350.057
Mouse Rat
neuron developmentGO:00486662620.056
cellular biosynthetic processGO:00442492860.055
Human
hemopoiesisGO:00300971830.054
nucleobase containing compound metabolic processGO:00061392740.053
Human
negative regulation of biological processGO:00485193040.052
immune system processGO:00023762410.052
Fly
regulation of cellular macromolecule biosynthetic processGO:20001122220.051
Human
regulation of signal transductionGO:00099662250.050
Mouse
aromatic compound biosynthetic processGO:00194382170.048
Human
regulation of biological qualityGO:00650082630.048
Mouse Rat Fly
cilium morphogenesisGO:0060271850.048
positive regulation of biological processGO:00485182530.047
Mouse Rat
immune system developmentGO:00025201910.047
rna localizationGO:000640340.046
regulation of macromolecule metabolic processGO:00602553170.046
Human Mouse
cell projection organizationGO:00300302840.045
Mouse Rat Fly
sensory organ developmentGO:00074233930.045
regulation of cellular metabolic processGO:00313233200.045
Human Mouse
agingGO:000756820.044
Fly
neuroblast proliferationGO:000740520.043
embryonic organ developmentGO:00485683810.043
chemosensory behaviorGO:000763510.043
maintenance of locationGO:005123540.042
synaptic growth at neuromuscular junctionGO:005112420.041
Fly
multicellular organism growthGO:003526440.041
angiogenesisGO:00015251580.040
generation of neuronsGO:00486993850.040
negative regulation of signal transductionGO:0009968940.039
cellular nitrogen compound metabolic processGO:00346412900.039
Human
transportGO:00068102200.039
Mouse Rat
exocytosisGO:000688710.039
Mouse Rat
regulation of stem cell proliferationGO:007209120.038
lymphangiogenesisGO:0001946250.037
cellular macromolecule metabolic processGO:00442603910.037
determination of left right symmetryGO:00073681790.037
hematopoietic or lymphoid organ developmentGO:00485341910.036
regulation of neural precursor cell proliferationGO:200017730.036
eye developmentGO:00016542770.035
organic cyclic compound biosynthetic processGO:19013622230.035
Human
organelle organizationGO:00069962270.034
chordate embryonic developmentGO:00430092710.034
neurotransmitter secretionGO:000726920.034
cellular component biogenesisGO:00440851780.034
Mouse Fly
blood vessel developmentGO:00015682460.034
meiotic cell cycle processGO:190304630.034
gene expressionGO:00104672520.034
Human
cellular component assemblyGO:00226071700.034
Mouse Fly
locomotor rhythmGO:004547530.033
neuron differentiationGO:00301823530.033
tube morphogenesisGO:00352393490.032
positive regulation of immune effector processGO:000269930.032
heterocycle biosynthetic processGO:00181302150.032
Human
neurotransmitter transportGO:000683620.032
locomotionGO:00400113130.032
Mouse Fly
establishment of localizationGO:00512342440.032
Mouse Rat
organic substance biosynthetic processGO:19015762890.032
Human
cellular aromatic compound metabolic processGO:00067252950.031
Human Fly
cell morphogenesisGO:00009022890.031
Mouse Rat Fly
establishment of protein localization to organelleGO:007259440.031
pole plasm assemblyGO:000731540.031
heart developmentGO:00075073130.031
regulation of organelle assemblyGO:190211540.030
regulation of exocytosisGO:001715710.030
Mouse
regulation of establishment of protein localizationGO:007020140.030
Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.029
Human
morphogenesis of an epitheliumGO:00020093330.029
regulation of macromolecule biosynthetic processGO:00105562250.029
Human
single organism organelle organizationGO:19025891990.029
cell surface receptor signaling pathwayGO:00071663250.028
positive regulation of cellular component biogenesisGO:004408930.028
regulation of synapse assemblyGO:005196330.028
Fly
regulation of cell communicationGO:00106462320.028
Mouse Rat
organic cyclic compound metabolic processGO:19013603010.028
Human Fly
cilium organizationGO:0044782710.028
positive regulation of secretion by cellGO:190353210.028
Mouse
protein localization to nucleusGO:003450430.028
cell deathGO:00082191210.027
meiotic nuclear divisionGO:000712640.027
brain developmentGO:00074202930.027
Mouse
circadian sleep wake cycleGO:004274520.027
extrinsic apoptotic signaling pathwayGO:009719130.027
positive regulation of cell cycleGO:004578730.027
nuclear transportGO:005116940.027
Mouse Rat
spermatid developmentGO:000728620.026
translational initiationGO:000641330.026
single organism transportGO:00447652060.026
Mouse Rat
regulation of cellular component organizationGO:0051128860.025
Mouse Fly
regulation of cellular amino acid metabolic processGO:000652100.025
single organism metabolic processGO:00447102170.025
rna metabolic processGO:00160702190.025
Human
regulation of transcription dna templatedGO:00063552130.025
Human
mitochondrion organizationGO:000700540.024
negative regulation of cell communicationGO:0010648960.024
regulation of cytoplasmic transportGO:190364940.024
Mouse
regulation of oocyte developmentGO:006028130.024
nucleic acid metabolic processGO:00903042440.024
Human
negative regulation of signalingGO:0023057960.024
intracellular signal transductionGO:0035556850.024
Fly
nephron tubule morphogenesisGO:007207810.024
intracellular mrna localizationGO:000829810.024
muscle organ developmentGO:00075171010.024
Mouse Rat
cell proliferationGO:0008283800.024
regulation of cell projection assemblyGO:006049140.024
guanosine containing compound catabolic processGO:190106920.023
larval developmentGO:000216420.023
determination of bilateral symmetryGO:00098552040.023
regulation of gene expressionGO:00104682650.023
Human
cellular component movementGO:00069283350.023
Mouse Fly
sensory organ morphogenesisGO:00905962000.023
digestive system developmentGO:00551232890.023
compound eye developmentGO:004874920.023
cell projection morphogenesisGO:00488582440.023
Mouse Rat Fly
renal tubule morphogenesisGO:006133310.022
regulation of protein complex assemblyGO:004325430.022
regulation of nitrogen compound metabolic processGO:00511712510.022
Human
regulation of transmembrane transporter activityGO:002289820.022
deathGO:00162651210.022
regulation of multicellular organismal processGO:00512392770.022
Mouse Fly
lipid storageGO:001991510.022
centrosome duplicationGO:005129810.022
centrosome organizationGO:005129710.022
positive regulation of secretionGO:005104710.022
Mouse
negative regulation of metabolic processGO:0009892860.022
Human Mouse
regulation of cell activationGO:005086510.022
regulation of protein transportGO:005122330.022
Mouse
regulation of protein ubiquitinationGO:003139630.022
Mouse
blood vessel morphogenesisGO:00485142160.022
protein dephosphorylationGO:000647030.022
positive regulation of exocytosisGO:004592110.022
Mouse
anterior posterior pattern specificationGO:00099521520.021
cellular protein catabolic processGO:004425740.021
phagocytosisGO:000690930.021
modification dependent macromolecule catabolic processGO:004363230.021
regulation of epithelial cell proliferationGO:005067830.021
regionalizationGO:00030022740.021
protein importGO:001703830.020
regulation of nucleic acid templated transcriptionGO:19035062130.020
Human
nephron epithelium morphogenesisGO:007208810.020
negative regulation of tor signalingGO:003200720.020
establishment of rna localizationGO:005123630.020
programmed cell deathGO:00125011190.020
meiotic chromosome segregationGO:004513230.020
rna biosynthetic processGO:00327741810.020
Human
liver developmentGO:0001889960.020
regulation of cytokine productionGO:000181730.020
establishment of protein localization to plasma membraneGO:009000210.020
stem cell divisionGO:001714510.020
negative regulation of multicellular organismal processGO:0051241690.020
Mouse
nucleic acid templated transcriptionGO:00976591810.020
Human
eye morphogenesisGO:00485921440.020
amine metabolic processGO:000930820.020
renal system developmentGO:0072001940.020
centrosome cycleGO:000709810.019
microtubule organizing center organizationGO:003102310.019
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.019
positive regulation of leukocyte differentiationGO:190210710.019
regulation of synapse organizationGO:005080730.019
Fly
spermatid differentiationGO:004851520.019
specification of symmetryGO:00097992040.019
cellular amine metabolic processGO:004410620.019
endosomal transportGO:001619720.019
female meiotic divisionGO:000714320.019
epithelial cell differentiationGO:00308551160.019
actin filament based movementGO:003004810.019
macromolecule biosynthetic processGO:00090592270.019
Human
positive regulation of neural precursor cell proliferationGO:200017910.019
regulation of rna metabolic processGO:00512522240.019
Human
biosynthetic processGO:00090582940.019
Human
regulation of bindingGO:005109830.018
Mouse
oocyte anterior posterior axis specificationGO:000731440.018
adult behaviorGO:003053420.018
Mouse Fly
b cell differentiationGO:003018310.018
adherens junction organizationGO:003433240.018
cytoplasm organizationGO:000702840.018
regulation of intracellular protein transportGO:003315730.018
Mouse
single organism localizationGO:19025782250.018
Mouse Rat
ubiquitin dependent protein catabolic processGO:000651130.018
muscle structure developmentGO:00610611960.018
Mouse Rat
stem cell maintenanceGO:001982740.018
protein localization to plasma membraneGO:007265910.018
protein targeting to nucleusGO:004474430.018
urogenital system developmentGO:0001655970.018
regulation of reactive oxygen species metabolic processGO:200037720.018
cilium assemblyGO:0042384580.017
nucleocytoplasmic transportGO:000691340.017
Mouse Rat
regulation of protein catabolic processGO:004217610.017
cell projection assemblyGO:0030031640.017
protein modification processGO:00362111000.017
circadian sleep wake cycle sleepGO:005080210.017
cellular component morphogenesisGO:00329893360.017
Mouse Rat Fly
germ line stem cell maintenanceGO:003071820.017
glucose homeostasisGO:004259310.017
nucleic acid transportGO:005065720.017
negative regulation of protein phosphorylationGO:000193340.017
protein secretionGO:000930610.017
regulation of multicellular organism growthGO:004001440.017
mesenchyme developmentGO:00604851270.017
positive regulation of nucleoside metabolic processGO:004597910.017
regulation of cell deathGO:00109411030.016
regulation of cellular amine metabolic processGO:003323800.016
behaviorGO:0007610740.016
Mouse Fly
gtp catabolic processGO:000618420.016
lateral inhibitionGO:004633110.016
cellular response to endogenous stimulusGO:0071495680.016
regulation of protein import into nucleusGO:004230620.016
regulation of dendrite developmentGO:005077330.016
Mouse
dorsal ventral pattern formationGO:00099531250.016
regulation of nucleoside metabolic processGO:000911820.016
modification dependent protein catabolic processGO:001994130.016
organelle assemblyGO:00709251100.016
regulation of response to stimulusGO:00485832690.016
Mouse
regulation of purine nucleotide catabolic processGO:003312120.016
regulation of reproductive processGO:200024140.016
positive regulation of cell divisionGO:005178120.016
positive regulation of cell activationGO:005086710.016
cell substrate adhesionGO:003158940.015
Mouse
regulation of metal ion transportGO:001095940.015
establishment of synaptic vesicle localizationGO:009748010.015
Rat
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
regulation of dna templated transcription elongationGO:003278430.015
hard palate developmentGO:006002240.015
transcription dna templatedGO:00063511810.015
Human
negative regulation of response to stimulusGO:00485851040.015
regulation of protein metabolic processGO:0051246560.015
Human Mouse
cellular response to radiationGO:007147840.015
cellular carbohydrate metabolic processGO:004426240.015
positive regulation of epithelial cell proliferationGO:005067910.015
regulation of erythrocyte differentiationGO:004564620.015
system processGO:00030081850.015
Mouse
meiosis iGO:000712710.015
determination of heart left right asymmetryGO:00613711170.015
pancreas developmentGO:0031016840.015
response to hexoseGO:000974630.015
dicarboxylic acid transportGO:000683510.015
regulation of ion transmembrane transporter activityGO:003241220.015
negative regulation of macromolecule metabolic processGO:0010605760.015
Human Mouse
positive regulation of nitrogen compound metabolic processGO:0051173690.015
calcium mediated signalingGO:001972220.015
positive regulation of muscle cell differentiationGO:005114910.015
positive regulation of cytokine productionGO:000181920.015
detection of mechanical stimulus involved in sensory perceptionGO:0050974110.015
nephron morphogenesisGO:007202820.015
positive regulation of cellular processGO:00485222010.014
Mouse Rat
embryo development ending in birth or egg hatchingGO:00097922710.014
response to chemicalGO:00422213200.014
Mouse Fly
response to endogenous stimulusGO:0009719830.014
Mouse
regulation of jak stat cascadeGO:004642530.014
Mouse
protein import into nucleusGO:000660630.014
oxoacid metabolic processGO:0043436310.014
positive regulation of cellular catabolic processGO:003133130.014
nuclear importGO:005117030.014
nitrogen compound transportGO:0071705230.014
localization of cellGO:00516742440.014
Mouse
cellular amide metabolic processGO:004360340.014
regulation of oligodendrocyte differentiationGO:004871310.014
proteolysis involved in cellular protein catabolic processGO:005160330.014
maternal determination of anterior posterior axis embryoGO:000835840.014
dna templated transcription elongationGO:000635430.014
cellular response to extracellular stimulusGO:003166820.014
skeletal system developmentGO:00015011810.014
kidney developmentGO:0001822920.014
apoptotic process involved in developmentGO:190274220.014
positive regulation of protein complex assemblyGO:003133420.014
cellular response to chemical stimulusGO:00708871570.014
muscle tissue developmentGO:00605371100.014
Mouse Rat
positive regulation of notch signaling pathwayGO:004574730.014
fertilizationGO:000956630.014
positive regulation of metabolic processGO:00098931080.014
Mouse
cellular macromolecule biosynthetic processGO:00346452240.014
Human
neural tube patterningGO:0021532330.014
synapsisGO:000712910.014
cell migrationGO:00164772370.014
Mouse
negative regulation of catabolic processGO:000989530.014
regulation of mitotic cell cycle embryonicGO:000979420.014
b cell activationGO:004211320.014
embryonic organ morphogenesisGO:00485622740.014
proteasomal protein catabolic processGO:001049820.014
positive regulation of cytoskeleton organizationGO:005149530.014
rna transportGO:005065820.013
positive regulation of catabolic processGO:000989640.013
regulation of circadian rhythmGO:004275240.013
nucleobase containing compound transportGO:001593120.013
negative regulation of cellular catabolic processGO:003133030.013
internal peptidyl lysine acetylationGO:001839320.013
lymph vessel morphogenesisGO:0036303250.013
peptide transportGO:001583310.013
cell morphogenesis involved in differentiationGO:00009041950.013
Mouse Fly
cytokinesisGO:000091030.013
apoptotic processGO:00069151160.013
positive regulation of striated muscle cell differentiationGO:005115510.013
epithelial tube morphogenesisGO:00605621480.013
nucleobase containing compound biosynthetic processGO:00346542050.013
Human
positive regulation of gtp catabolic processGO:003312610.013
gastrulationGO:00073692080.013
cell part morphogenesisGO:00329902460.013
Mouse Rat Fly
mononuclear cell proliferationGO:003294310.013
regulation of transporter activityGO:003240920.013
signal transduction in absence of ligandGO:003803410.013
guanosine containing compound metabolic processGO:190106840.013
neuromuscular synaptic transmissionGO:000727420.013
response to drugGO:004249330.013
meiotic spindle organizationGO:000021210.013
proximal distal pattern formationGO:000995410.013
gland developmentGO:00487321430.013
embryonic heart tube morphogenesisGO:00031431080.013
pronephros developmentGO:0048793690.013
negative regulation of translationGO:001714810.013
positive regulation of striated muscle tissue developmentGO:004584410.013
developmental programmed cell deathGO:001062340.013
cellular component disassemblyGO:002241110.013
lymph vessel developmentGO:0001945270.013
circadian sleep wake cycle processGO:002241020.013
myeloid cell homeostasisGO:0002262560.013
retina development in camera type eyeGO:00600411460.013
synaptic vesicle localizationGO:009747910.013
Rat
tissue remodelingGO:004877140.013
regulation of protein targetingGO:190353320.013
Mouse
cellular amino acid metabolic processGO:000652070.013
carboxylic acid metabolic processGO:0019752220.012
membrane fusionGO:006102520.012
pronephros morphogenesisGO:0072114140.012
gtp metabolic processGO:004603940.012
regulation of nucleotide catabolic processGO:003081120.012
transcription elongation from rna polymerase ii promoterGO:000636830.012
response to external stimulusGO:00096052640.012
Mouse Fly
positive regulation of purine nucleotide catabolic processGO:003312310.012
peptidyl lysine acetylationGO:001839420.012
axon developmentGO:00615641660.012
Mouse Fly
peptidyl serine modificationGO:001820920.012
Human Mouse Rat
positive regulation of signal transductionGO:0009967560.012
positive regulation of response to stimulusGO:0048584800.012
erythrocyte differentiationGO:0030218540.012
protein metabolic processGO:00195381830.012
regulation of glial cell differentiationGO:004568540.012
cellular response to biotic stimulusGO:007121630.012
organonitrogen compound metabolic processGO:1901564740.012
cellular component assembly involved in morphogenesisGO:00109271070.012
cellular response to nutrient levelsGO:003166920.012
positive regulation of multi organism processGO:004390230.012
mrna transportGO:005102820.012
nuclear exportGO:005116810.012
Mouse
homeostatic processGO:00425921420.012
cell agingGO:000756920.012
muscle fiber developmentGO:0048747520.012
regulation of biosynthetic processGO:00098892500.012
Human
striated muscle cell differentiationGO:00511461290.012
growthGO:00400071740.012
Mouse Fly
regulation of protein modification by small protein conjugation or removalGO:190332030.012
Mouse
regulation of nucleocytoplasmic transportGO:004682220.012
Mouse
cytoskeleton dependent cytokinesisGO:006164030.012
leukocyte proliferationGO:007066110.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
hepaticobiliary system developmentGO:0061008980.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
negative regulation of synapse assemblyGO:005196420.012
single organism nuclear importGO:190259330.012
regulation of primary metabolic processGO:00800903110.012
Human Mouse
positive regulation of cellular metabolic processGO:0031325940.011
Mouse
developmental growthGO:00485891660.011
Mouse Fly
cellular transition metal ion homeostasisGO:004691630.011
positive regulation of nucleotide catabolic processGO:003081310.011
macromolecule modificationGO:00434121110.011
regulation of cellular carbohydrate metabolic processGO:001067540.011
intracellular transportGO:0046907320.011
Mouse Rat
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
cartilage developmentGO:0051216960.011
organic acid metabolic processGO:0006082310.011
regulation of production of molecular mediator of immune responseGO:000270010.011
negative regulation of epithelial cell proliferationGO:005068010.011
somatic muscle developmentGO:000752540.011
regulation of protein localization to nucleusGO:190018020.011
digestive tract developmentGO:00485652650.011
alcohol biosynthetic processGO:004616520.011
response to stressGO:00069502630.011
Rat Fly
negative regulation of intracellular protein transportGO:009031730.011
Mouse
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
protein targeting to membraneGO:000661210.011
Mouse
establishment of localization in cellGO:0051649770.011
Mouse Rat
response to organic substanceGO:00100331530.011
Mouse
regulation of neurological system processGO:003164420.011
digestive tract morphogenesisGO:00485462310.011
macromolecular complex subunit organizationGO:0043933740.011
negative regulation of gene expressionGO:0010629650.011
Human
axis specificationGO:0009798430.011
enzyme linked receptor protein signaling pathwayGO:00071671060.011
aorta developmentGO:003590440.011
response to monosaccharideGO:003428430.011
organism emergence from protective structureGO:007168440.011
positive regulation of leukocyte mediated immunityGO:000270510.011
membrane invaginationGO:001032410.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
Mouse
negative regulation of kinase activityGO:003367340.011
protein polyubiquitinationGO:000020940.011
specification of axis polarityGO:006500140.011
ribonucleoside monophosphate catabolic processGO:000915840.011
positive regulation of myeloid cell differentiationGO:004563920.011
negative regulation of wnt signaling pathwayGO:0030178300.011
mitotic cell cycleGO:0000278640.011
Fly
regulation of apoptotic processGO:0042981980.011
protein acylationGO:004354330.011
protein homooligomerizationGO:005126030.011
post embryonic morphogenesisGO:000988640.011
camera type eye developmentGO:00430102220.011
rna 3 end processingGO:003112320.011
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.011
transcription from rna polymerase ii promoterGO:0006366800.010
atp catabolic processGO:000620040.010
negative regulation of myeloid cell differentiationGO:004563810.010
protein polymerizationGO:005125840.010
peptidyl threonine modificationGO:001821010.010
Mouse
positive regulation of translationGO:004572710.010
regulation of dendrite morphogenesisGO:004881430.010
Mouse
muscle cell migrationGO:001481240.010
regulation of wnt signaling pathwayGO:0030111530.010
regulation of cellular protein catabolic processGO:190336210.010
response to abiotic stimulusGO:00096281220.010
Mouse
pronuclear migrationGO:003504610.010
hormone secretionGO:004687920.010
spindle assembly involved in meiosisGO:009030610.010
regulation of cellular biosynthetic processGO:00313262450.010
Human
regulation of anatomical structure morphogenesisGO:00226031300.010
Mouse
wnt signaling pathwayGO:0016055800.010
cell substrate junction assemblyGO:000704420.010
cellular response to organic substanceGO:00713101050.010
actin polymerization or depolymerizationGO:000815420.010
peptidyl serine phosphorylationGO:001810510.010
Human Mouse Rat
striated muscle cell developmentGO:00550021080.010
response to carbohydrateGO:000974330.010
chromosome organization involved in meiosisGO:007019210.010
carbohydrate homeostasisGO:003350010.010
retina morphogenesis in camera type eyeGO:0060042790.010
cell cell signalingGO:0007267520.010
Mouse Rat Fly

cdk5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.053
disease of cellular proliferationDOID:1456600.028
cancerDOID:16200.017
organ system cancerDOID:005068600.017
nervous system diseaseDOID:86300.014
musculoskeletal system diseaseDOID:1700.012
disease of metabolismDOID:001466700.012