Danio rerio

0 known processes

cdk8

cyclin-dependent kinase 8

(Aliases: wu:fk95h11)

cdk8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cellular processGO:00485232830.597
Yeast Fly
regulation of gene expressionGO:00104682650.564
Yeast
regulation of cellular biosynthetic processGO:00313262450.517
Yeast
larval developmentGO:000216420.443
Worm
regulation of metabolic processGO:00192223590.368
Yeast
regulation of macromolecule metabolic processGO:00602553170.360
Yeast
gene expressionGO:00104672520.336
Yeast Fly
biosynthetic processGO:00090582940.302
Yeast
morphogenesis of an epitheliumGO:00020093330.197
macromolecule biosynthetic processGO:00090592270.193
Yeast
positive regulation of biological processGO:00485182530.182
Yeast
modification dependent protein catabolic processGO:001994130.181
negative regulation of biological processGO:00485193040.168
Yeast Worm Fly
regulation of cellular metabolic processGO:00313233200.164
Yeast
regulation of developmental processGO:00507932470.161
Worm
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.161
regulation of macromolecule biosynthetic processGO:00105562250.159
Yeast
cellular macromolecule metabolic processGO:00442603910.156
Yeast Fly
organic substance biosynthetic processGO:19015762890.148
Yeast
regulation of multicellular organismal processGO:00512392770.144
Worm
axonogenesisGO:00074091520.144
Fly
regulation of primary metabolic processGO:00800903110.143
Yeast
cytokinesisGO:000091030.135
cellular biosynthetic processGO:00442492860.130
Yeast
transportGO:00068102200.125
proteolysis involved in cellular protein catabolic processGO:005160330.123
developmental growthGO:00485891660.118
lateral inhibitionGO:004633110.117
mitotic dna damage checkpointGO:004477340.113
Fly
posttranscriptional regulation of gene expressionGO:0010608140.110
Yeast
regulation of anatomical structure morphogenesisGO:00226031300.106
cellular macromolecule biosynthetic processGO:00346452240.104
Yeast
regulation of biosynthetic processGO:00098892500.101
Yeast
cell morphogenesis involved in neuron differentiationGO:00486671630.098
Fly
aromatic compound biosynthetic processGO:00194382170.095
Yeast
heart developmentGO:00075073130.094
cellular response to extracellular stimulusGO:003166820.093
Yeast
mitotic cell cycle processGO:1903047480.093
Fly
cellular nitrogen compound metabolic processGO:00346412900.092
Yeast Fly
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.092
nucleus organizationGO:000699770.092
positive regulation of jnk cascadeGO:004633030.091
locomotionGO:00400113130.088
Fly
mitotic dna integrity checkpointGO:004477440.088
Fly
negative regulation of macromolecule metabolic processGO:0010605760.086
Yeast
response to stressGO:00069502630.085
Fly
specification of organ identityGO:001009220.085
response to external stimulusGO:00096052640.084
Yeast Fly
ubiquitin dependent protein catabolic processGO:000651130.081
positive regulation of jun kinase activityGO:004350720.081
cell migrationGO:00164772370.080
mitotic g2 m transition checkpointGO:004481830.080
Fly
embryo development ending in birth or egg hatchingGO:00097922710.078
Worm
multi organism processGO:00517041340.078
translational initiationGO:000641330.078
regulation of nucleic acid templated transcriptionGO:19035062130.073
Yeast
regulation of multicellular organism growthGO:004001440.072
gene silencing by rnaGO:003104740.071
heterocycle biosynthetic processGO:00181302150.071
Yeast
chordate embryonic developmentGO:00430092710.070
negative regulation of metabolic processGO:0009892860.069
Yeast
positive regulation of map kinase activityGO:004340630.069
negative regulation of biosynthetic processGO:0009890550.069
Yeast
posttranscriptional gene silencingGO:001644130.068
modification dependent macromolecule catabolic processGO:004363230.068
regulation of multicellular organismal developmentGO:20000262230.067
Worm
proteasomal protein catabolic processGO:001049820.067
positive regulation of transportGO:005105020.065
establishment of localizationGO:00512342440.063
regulation of nucleocytoplasmic transportGO:004682220.063
sensory organ developmentGO:00074233930.062
Fly
regulation of translational initiationGO:000644610.061
negative regulation of cell cycle phase transitionGO:190198850.060
Fly
positive regulation of stress activated mapk cascadeGO:003287430.059
regulation of rna metabolic processGO:00512522240.058
Yeast
regulation of nitrogen compound metabolic processGO:00511712510.058
Yeast
regulation of cell differentiationGO:00455951420.058
nucleobase containing compound metabolic processGO:00061392740.056
Yeast Fly
nucleic acid metabolic processGO:00903042440.055
Yeast Fly
locomotor rhythmGO:004547530.054
stem cell divisionGO:001714510.054
posttranscriptional gene silencing by rnaGO:003519430.054
intracellular signal transductionGO:0035556850.051
meiotic nuclear divisionGO:000712640.051
regulation of protein catabolic processGO:004217610.051
cytoskeleton organizationGO:0007010960.050
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.050
transcription dna templatedGO:00063511810.050
Yeast
epithelial tube morphogenesisGO:00605621480.049
protein metabolic processGO:00195381830.049
Yeast Fly
positive regulation of cellular processGO:00485222010.049
Yeast
organelle organizationGO:00069962270.048
regulation of extrinsic apoptotic signaling pathwayGO:200123630.048
regulation of gene expression epigeneticGO:0040029110.048
convergent extensionGO:00600261180.048
neuron projection developmentGO:00311751800.048
Fly
negative regulation of cellular protein metabolic processGO:0032269160.047
cellular protein catabolic processGO:004425740.047
axon developmentGO:00615641660.046
Fly
regulation of signal transductionGO:00099662250.046
multicellular organism reproductionGO:0032504350.046
nitrogen compound metabolic processGO:00068073190.045
Yeast Fly
taxisGO:00423301090.045
Fly
positive regulation of metabolic processGO:00098931080.045
Yeast
deathGO:00162651210.045
multi organism reproductive processGO:0044703360.045
g2 dna damage checkpointGO:003157230.044
Fly
protein localization to nucleusGO:003450430.044
cellular response to nutrient levelsGO:003166920.044
Yeast
small gtpase mediated signal transductionGO:000726480.044
meiotic cell cycle processGO:190304630.044
regulation of nucleobase containing compound metabolic processGO:00192192500.043
Yeast
multicellular organism growthGO:003526440.043
regulation of response to stimulusGO:00485832690.043
rna metabolic processGO:00160702190.042
Yeast Fly
regulation of mrna splicing via spliceosomeGO:004802430.042
protein import into nucleusGO:000660630.042
nuclear transportGO:005116940.042
defense responseGO:0006952470.042
organic cyclic compound biosynthetic processGO:19013622230.042
Yeast
digestive tract developmentGO:00485652650.041
regulation of alternative mrna splicing via spliceosomeGO:000038110.041
generation of neuronsGO:00486993850.041
Fly
ameboidal type cell migrationGO:00016671430.040
stem cell maintenanceGO:001982740.040
nucleic acid templated transcriptionGO:00976591810.040
Yeast
single organism organelle organizationGO:19025891990.039
cell growthGO:0016049570.039
regulation of protein localization to nucleusGO:190018020.039
response to chemicalGO:00422213200.039
Yeast Fly
cellular component movementGO:00069283350.039
Fly
rna biosynthetic processGO:00327741810.038
Yeast
negative regulation of gene expressionGO:0010629650.038
Yeast
cellular protein metabolic processGO:00442671290.038
Yeast Fly
phagocytosisGO:000690930.038
system processGO:00030081850.038
cellular localizationGO:0051641970.038
single organism metabolic processGO:00447102170.038
lamellipodium assemblyGO:003003210.038
regulation of developmental growthGO:0048638380.038
cell cell signaling involved in cell fate commitmentGO:0045168120.037
immune system processGO:00023762410.037
cellular component biogenesisGO:00440851780.037
cellular process involved in reproduction in multicellular organismGO:0022412280.037
agingGO:000756820.036
response to light stimulusGO:0009416460.036
cellular response to stressGO:0033554620.036
Fly
tube morphogenesisGO:00352393490.036
regulation of synapse organizationGO:005080730.036
mitotic cell cycle checkpointGO:000709350.036
Fly
negative regulation of cellular metabolic processGO:0031324770.036
Yeast
response to abiotic stimulusGO:00096281220.035
cell morphogenesis involved in differentiationGO:00009041950.034
Fly
maintenance of locationGO:005123540.034
nucleocytoplasmic transportGO:000691340.034
regulation of establishment of protein localizationGO:007020140.034
cell fate commitmentGO:0045165990.034
regionalizationGO:00030022740.034
Fly
rna localizationGO:000640340.034
regulation of establishment of planar polarityGO:009017540.034
cell adhesionGO:0007155400.033
regulation of synapse assemblyGO:005196330.033
positive regulation of cellular catabolic processGO:003133130.032
regulation of response to nutrient levelsGO:003210710.032
regulation of biological qualityGO:00650082630.032
Yeast
secondary metabolic processGO:001974830.031
mrna metabolic processGO:0016071200.031
Yeast
cellular response to external stimulusGO:007149620.030
Yeast
establishment of protein localization to organelleGO:007259440.030
stem cell proliferationGO:007208940.030
macromolecular complex subunit organizationGO:0043933740.030
cellular aromatic compound metabolic processGO:00067252950.030
Yeast Fly
cell part morphogenesisGO:00329902460.030
Fly
organonitrogen compound metabolic processGO:1901564740.030
signal transductionGO:00071654550.029
cell substrate adhesionGO:003158940.029
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377100.029
cellular component morphogenesisGO:00329893360.029
Fly
single organism transportGO:00447652060.029
growthGO:00400071740.029
Yeast
response to biotic stimulusGO:0009607970.029
negative regulation of translationGO:001714810.029
mitotic g2 dna damage checkpointGO:000709530.029
Fly
regulation of cellular protein catabolic processGO:190336210.028
protein importGO:001703830.028
localization of cellGO:00516742440.027
rna splicingGO:0008380160.027
negative chemotaxisGO:005091910.027
regulation of molecular functionGO:0065009700.027
positive regulation of signalingGO:0023056560.027
organic cyclic compound metabolic processGO:19013603010.027
Yeast Fly
protein complex disassemblyGO:004324110.027
programmed cell deathGO:00125011190.027
regulation of establishment or maintenance of cell polarityGO:003287820.027
regulation of cytoplasmic transportGO:190364940.027
neuroblast proliferationGO:000740520.027
regulation of response to extracellular stimulusGO:003210410.026
regulation of mrna processingGO:005068430.026
response to bacteriumGO:0009617580.026
microtubule based processGO:0007017600.026
establishment of epithelial cell apical basal polarityGO:004519820.026
digestive tract morphogenesisGO:00485462310.026
negative regulation of cellular catabolic processGO:003133030.025
regulation of exocytosisGO:001715710.025
protein targeting to nucleusGO:004474430.025
developmental growth involved in morphogenesisGO:0060560860.025
protein polymerizationGO:005125840.025
wnt signaling pathway planar cell polarity pathwayGO:006007140.025
response to external biotic stimulusGO:0043207970.025
adult behaviorGO:003053420.024
regulation of reproductive processGO:200024140.024
negative regulation of stem cell differentiationGO:200073720.024
gene silencingGO:001645840.024
chemotaxisGO:00069351040.024
Fly
amide biosynthetic processGO:004360410.024
macromolecular complex disassemblyGO:003298410.024
regulation of protein metabolic processGO:0051246560.024
behaviorGO:0007610740.024
lamellipodium organizationGO:009758110.023
positive regulation of rna splicingGO:003312010.023
dna damage checkpointGO:000007760.023
Fly
regulation of growthGO:0040008420.023
Yeast
regulation of cell adhesionGO:0030155150.023
negative regulation of protein processingGO:0010955100.023
meiosis iGO:000712710.023
nuclear pore organizationGO:000699920.023
oogenesisGO:0048477140.023
negative regulation of developmental processGO:0051093650.023
Worm
neuron developmentGO:00486662620.022
Fly
multicellular organismal reproductive processGO:0048609350.022
cellular component assemblyGO:00226071700.022
gastrulationGO:00073692080.022
negative regulation of catabolic processGO:000989530.022
peptide metabolic processGO:000651810.022
central nervous system developmentGO:00074173870.022
regulation of protein import into nucleusGO:004230620.021
response to radiationGO:0009314510.021
positive regulation of response to stimulusGO:0048584800.021
regulation of protein transportGO:005122330.021
digestive system developmentGO:00551232890.021
negative regulation of response to stimulusGO:00485851040.021
cellular amide metabolic processGO:004360340.021
extrinsic apoptotic signaling pathwayGO:009719130.021
angioblast cell migration involved in selective angioblast sproutingGO:003547540.021
regulation of system processGO:0044057400.021
nucleobase containing compound biosynthetic processGO:00346542050.021
Yeast
cellular response to starvationGO:000926710.021
regulation of jun kinase activityGO:004350630.021
positive regulation of developmental processGO:0051094500.021
positive regulation of lipase activityGO:006019310.021
regulation of cell developmentGO:00602841000.020
cell projection morphogenesisGO:00488582440.020
Fly
gamete generationGO:0007276330.020
negative regulation of chromosome organizationGO:200125110.020
signal transduction by phosphorylationGO:0023014180.020
cellular component disassemblyGO:002241110.020
nuclear envelope organizationGO:000699820.020
spermatid developmentGO:000728620.020
negative regulation of defense responseGO:003134820.020
apoptotic signaling pathwayGO:0097190230.020
establishment or maintenance of monopolar cell polarityGO:006133920.019
regulation of circadian rhythmGO:004275240.019
autophagyGO:000691440.019
single organism localizationGO:19025782250.019
stem cell differentiationGO:00488631170.019
cell surface receptor signaling pathwayGO:00071663250.019
cell migration involved in gastrulationGO:0042074790.019
regulation of response to biotic stimulusGO:000283120.019
regulation of autophagyGO:001050630.019
angioblast cell migrationGO:003547690.019
positive regulation of exocytosisGO:004592110.019
negative regulation of protein metabolic processGO:0051248160.018
exocytosisGO:000688710.018
actin filament bundle organizationGO:006157260.018
skin developmentGO:0043588540.018
germ line stem cell divisionGO:004207810.018
heart morphogenesisGO:00030071560.018
positive regulation of multicellular organismal processGO:0051240520.018
innate immune responseGO:0045087130.018
macroautophagyGO:001623610.018
protein stabilizationGO:005082120.018
regulation of cellular protein metabolic processGO:0032268520.018
regulation of transcription dna templatedGO:00063552130.018
Yeast
ribonucleoside monophosphate catabolic processGO:000915840.018
regulation of cellular macromolecule biosynthetic processGO:20001122220.018
Yeast
proteolysisGO:0006508380.018
regulation of cell deathGO:00109411030.018
regulation of apoptotic processGO:0042981980.017
cell deathGO:00082191210.017
spliceosomal snrnp assemblyGO:000038720.017
organic acid metabolic processGO:0006082310.017
reproductionGO:0000003400.017
Worm
response to other organismGO:0051707970.017
regulation of signalingGO:00230512350.017
macromolecule localizationGO:0033036540.017
nuclear importGO:005117030.017
regulation of jak stat cascadeGO:004642530.017
vasculature developmentGO:00019442780.017
regulation of production of molecular mediator of immune responseGO:000270010.017
establishment of apical basal cell polarityGO:003508920.017
regulation of protein complex assemblyGO:004325430.017
apoptotic processGO:00069151160.017
regulation of microtubule cytoskeleton organizationGO:007050730.017
response to carbohydrateGO:000974330.016
cell motilityGO:00488702440.016
heart formationGO:0060914130.016
activation of mapk activityGO:000018730.016
alternative mrna splicing via spliceosomeGO:000038010.016
regulation of intracellular protein transportGO:003315730.016
regulation of wound healingGO:006104120.016
negative regulation of signal transductionGO:0009968940.016
atp catabolic processGO:000620040.016
single organism reproductive processGO:0044702400.016
protein processingGO:0016485120.016
cell cell signalingGO:0007267520.016
melanin metabolic processGO:000658220.015
blood vessel developmentGO:00015682460.015
positive regulation of secretion by cellGO:190353210.015
response to uvGO:000941130.015
specification of symmetryGO:00097992040.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
Yeast
regulation of cell communicationGO:00106462320.015
defense response to bacteriumGO:0042742220.015
regulation of catalytic activityGO:0050790550.015
olfactory lobe developmentGO:002198840.015
cell proliferationGO:0008283800.015
positive regulation of secretionGO:005104710.015
dorsal ventral pattern formationGO:00099531250.015
regulation of protein complex disassemblyGO:004324410.014
cellular nitrogen compound biosynthetic processGO:00442712180.014
Yeast
cell projection assemblyGO:0030031640.014
establishment of epithelial cell polarityGO:009016220.014
cell projection organizationGO:00300302840.014
Fly
gland developmentGO:00487321430.014
single organism biosynthetic processGO:0044711710.014
cell morphogenesisGO:00009022890.014
Fly
convergent extension involved in organogenesisGO:0060029100.014
positive regulation of immune effector processGO:000269930.014
actin filament polymerizationGO:003004120.014
positive regulation of macromolecule metabolic processGO:0010604930.014
Yeast
negative regulation of nitrogen compound metabolic processGO:0051172590.014
Yeast
organism emergence from protective structureGO:007168440.014
oxoacid metabolic processGO:0043436310.014
epidermis morphogenesisGO:004873040.014
development of primary female sexual characteristicsGO:004654540.014
synaptic target recognitionGO:000803910.014
mitotic cell cycleGO:0000278640.014
Fly
negative regulation of cellular biosynthetic processGO:0031327550.013
Yeast
motor neuron axon guidanceGO:0008045230.013
positive regulation of cellular amine metabolic processGO:003324000.013
nucleoside monophosphate catabolic processGO:000912540.013
cellular macromolecule catabolic processGO:0044265120.013
Yeast
positive regulation of cell cycleGO:004578730.013
lipid storageGO:001991510.013
regulation of cell matrix adhesionGO:000195210.013
gene silencing by mirnaGO:003519530.013
cell cycle checkpointGO:000007570.013
Fly
regulation of microtubule based movementGO:006063230.013
sexual reproductionGO:0019953360.013
positive regulation of signal transductionGO:0009967560.013
antimicrobial humoral responseGO:001973020.013
negative regulation of small gtpase mediated signal transductionGO:005105810.013
female gonad developmentGO:000858540.013
positive regulation of apoptotic processGO:0043065290.013
regulation of response to stressGO:0080134360.012
segmentationGO:0035282970.012
Fly
positive regulation of mrna metabolic processGO:190331320.012
positive regulation of catalytic activityGO:0043085250.012
tube closureGO:006060610.012
negative regulation of macromolecule biosynthetic processGO:0010558480.012
Yeast
rna transportGO:005065820.012
reproductive processGO:0022414400.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
heart contractionGO:0060047710.012
regulation of stem cell differentiationGO:200073640.012
negative regulation of mitotic cell cycleGO:0045930110.012
Fly
meiotic spindle organizationGO:000021210.012
spermatid differentiationGO:004851520.012
negative regulation of multi organism processGO:004390130.012
protein kinase b signalingGO:004349190.012
brain developmentGO:00074202930.012
regulation of chromosome segregationGO:005198310.012
regulation of cell cycle processGO:0010564200.012
Fly
defense response to gram negative bacteriumGO:005082980.012
female gamete generationGO:0007292140.012
chromosome organization involved in meiosisGO:007019210.012
regulation of nucleoside metabolic processGO:000911820.011
muscle cell migrationGO:001481240.011
endodermal cell fate commitmentGO:0001711180.011
regulation of proteolysisGO:0030162240.011
response to organic substanceGO:00100331530.011
inner ear developmentGO:00488391260.011
stem cell developmentGO:0048864820.011
vacuolar transportGO:000703420.011
heterocycle metabolic processGO:00464832900.011
Yeast Fly
gtp catabolic processGO:000618420.011
positive regulation of dna metabolic processGO:005105410.011
single organism nuclear importGO:190259330.011
negative regulation of neuron projection regenerationGO:007057140.011
skin morphogenesisGO:004358970.011
epidermis developmentGO:0008544480.011
protein complex localizationGO:003150310.011
inorganic ion transmembrane transportGO:0098660570.011
positive regulation of mrna splicing via spliceosomeGO:004802610.011
cell cycle g1 s phase transitionGO:004484310.011
Fly
positive regulation of protein kinase b signalingGO:005189710.011
cellular macromolecule localizationGO:0070727210.011
positive regulation of cell adhesionGO:004578510.011
asymmetric protein localizationGO:000810560.011
axis elongationGO:0003401310.011
regulation of rna biosynthetic processGO:20011412130.010
Yeast
negative regulation of cell communicationGO:0010648960.010
negative regulation of signalingGO:0023057960.010
heart processGO:0003015710.010
gtp metabolic processGO:004603940.010
protein n linked glycosylationGO:000648710.010
morphogenesis of an epithelial sheetGO:0002011490.010
purine nucleoside monophosphate catabolic processGO:000912840.010
regulation of immune system processGO:0002682340.010
glycosaminoglycan biosynthetic processGO:000602480.010
female sex differentiationGO:004666040.010
production of molecular mediator of immune responseGO:000244020.010
negative regulation of cell developmentGO:0010721260.010
polarized epithelial cell differentiationGO:003085940.010
cell migration involved in heart developmentGO:0060973220.010

cdk8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.020
disease of anatomical entityDOID:700.019
organ system cancerDOID:005068600.019
cancerDOID:16200.019