Danio rerio

0 known processes

hk2

hexokinase 2

(Aliases: zgc:55926,wu:fi31b04,wu:fi09d05,wu:fi17h06,fi17h06,fi09d05)

hk2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
generation of neuronsGO:00486993850.514
neuron differentiationGO:00301823530.449
neuron projection developmentGO:00311751800.298
single organism metabolic processGO:00447102170.267
Mouse
small molecule metabolic processGO:0044281770.262
cell projection organizationGO:00300302840.216
neuron projection morphogenesisGO:00488121610.212
cell morphogenesisGO:00009022890.198
axon developmentGO:00615641660.196
single organism transportGO:00447652060.193
Mouse
signal transductionGO:00071654550.189
positive regulation of biological processGO:00485182530.184
axonogenesisGO:00074091520.168
cellular biosynthetic processGO:00442492860.151
regulation of biological qualityGO:00650082630.150
cellular component assemblyGO:00226071700.144
immune system processGO:00023762410.137
cellular component morphogenesisGO:00329893360.134
response to external stimulusGO:00096052640.130
embryo development ending in birth or egg hatchingGO:00097922710.127
cell morphogenesis involved in differentiationGO:00009041950.125
positive regulation of cellular component biogenesisGO:004408930.124
response to chemicalGO:00422213200.124
organic substance biosynthetic processGO:19015762890.104
regulation of cytoplasmic transportGO:190364940.104
membrane fusionGO:006102520.104
neuron developmentGO:00486662620.100
deathGO:00162651210.099
Human Mouse
response to organic substanceGO:00100331530.095
heterocycle metabolic processGO:00464832900.094
gtp metabolic processGO:004603940.093
larval developmentGO:000216420.093
cell projection morphogenesisGO:00488582440.091
central nervous system developmentGO:00074173870.090
single organism localizationGO:19025782250.088
Mouse
cell morphogenesis involved in neuron differentiationGO:00486671630.087
regulation of cellular biosynthetic processGO:00313262450.085
response to stressGO:00069502630.084
vasculature developmentGO:00019442780.083
regulation of protein complex assemblyGO:004325430.083
cellular nitrogen compound metabolic processGO:00346412900.080
oxoacid metabolic processGO:0043436310.080
agingGO:000756820.079
organelle fusionGO:004828430.079
response to antibioticGO:004667710.078
cell substrate adhesionGO:003158940.078
positive regulation of transportGO:005105020.078
organonitrogen compound metabolic processGO:1901564740.077
cellular aromatic compound metabolic processGO:00067252950.077
regulation of response to stimulusGO:00485832690.076
cellular component biogenesisGO:00440851780.075
single organism biosynthetic processGO:0044711710.075
regulation of establishment of protein localizationGO:007020140.073
eye morphogenesisGO:00485921440.072
regulation of signalingGO:00230512350.072
lipid storageGO:001991510.071
cell part morphogenesisGO:00329902460.070
muscle cell developmentGO:00550011150.069
eye developmentGO:00016542770.068
cognitionGO:005089010.068
cellular response to chemical stimulusGO:00708871570.067
striated muscle cell developmentGO:00550021080.067
guanosine containing compound metabolic processGO:190106840.066
adult behaviorGO:003053420.064
cellular nitrogen compound biosynthetic processGO:00442712180.063
single organism membrane fusionGO:004480120.062
sensory organ developmentGO:00074233930.061
response to drugGO:004249330.057
response to biotic stimulusGO:0009607970.056
mitochondrion organizationGO:000700540.056
Human Mouse
cytokinesisGO:000091030.056
regulation of protein transportGO:005122330.055
synaptic growth at neuromuscular junctionGO:005112420.055
chordate embryonic developmentGO:00430092710.053
cellular amino acid metabolic processGO:000652070.052
regulation of synapse assemblyGO:005196330.052
regulation of cell communicationGO:00106462320.050
proteolysis involved in cellular protein catabolic processGO:005160330.049
determination of bilateral symmetryGO:00098552040.049
cellular carbohydrate metabolic processGO:004426240.049
Mouse
positive regulation of protein complex assemblyGO:003133420.048
maintenance of locationGO:005123540.048
head developmentGO:00603223030.047
establishment of localization in cellGO:0051649770.047
organic acid metabolic processGO:0006082310.047
system processGO:00030081850.047
regulation of primary metabolic processGO:00800903110.047
biosynthetic processGO:00090582940.046
regulation of metabolic processGO:00192223590.046
establishment of localizationGO:00512342440.046
Mouse
embryonic organ developmentGO:00485683810.045
protein localization to plasma membraneGO:007265910.043
organic cyclic compound metabolic processGO:19013603010.043
protein metabolic processGO:00195381830.043
meiotic cell cycle processGO:190304630.043
protein polymerizationGO:005125840.042
multi organism processGO:00517041340.042
regulation of gene expressionGO:00104682650.042
macromolecule biosynthetic processGO:00090592270.041
cellular response to nutrient levelsGO:003166920.041
locomotionGO:00400113130.041
positive regulation of cellular processGO:00485222010.041
positive regulation of immune effector processGO:000269930.041
nitrogen compound metabolic processGO:00068073190.041
gene expressionGO:00104672520.040
nucleobase containing compound metabolic processGO:00061392740.040
phosphate containing compound metabolic processGO:00067961080.040
Mouse
gtp catabolic processGO:000618420.039
regulation of developmental processGO:00507932470.039
actin polymerization or depolymerizationGO:000815420.039
blood vessel developmentGO:00015682460.039
organelle organizationGO:00069962270.038
Human Mouse
cellular macromolecule biosynthetic processGO:00346452240.038
blood vessel morphogenesisGO:00485142160.038
organelle assemblyGO:00709251100.038
cellular response to external stimulusGO:007149620.038
positive regulation of cellular catabolic processGO:003133130.037
striated muscle cell differentiationGO:00511461290.037
regulation of multicellular organismal developmentGO:20000262230.037
negative regulation of cellular processGO:00485232830.037
meiotic nuclear divisionGO:000712640.036
positive regulation of blood circulationGO:190352420.036
positive regulation of cell cycleGO:004578730.035
carboxylic acid metabolic processGO:0019752220.035
cellular component assembly involved in morphogenesisGO:00109271070.035
single organism organelle organizationGO:19025891990.035
cell deathGO:00082191210.034
Human Mouse
immune system developmentGO:00025201910.034
guanosine containing compound catabolic processGO:190106920.034
glucose importGO:004632320.034
Mouse
regulation of synapse organizationGO:005080730.034
positive regulation of catabolic processGO:000989640.034
ion transportGO:00068111140.034
neurotransmitter transportGO:000683620.033
response to external biotic stimulusGO:0043207970.033
apoptotic processGO:00069151160.032
Human Mouse
response to other organismGO:0051707970.032
neurotransmitter secretionGO:000726920.032
transportGO:00068102200.031
Mouse
hematopoietic or lymphoid organ developmentGO:00485341910.031
cellular protein catabolic processGO:004425740.031
positive regulation of nucleoside metabolic processGO:004597910.030
peptidyl serine phosphorylationGO:001810510.030
response to organic cyclic compoundGO:0014070510.030
heart developmentGO:00075073130.030
regulation of nitrogen compound metabolic processGO:00511712510.030
embryonic hemopoiesisGO:0035162530.030
cellular macromolecule metabolic processGO:00442603910.030
response to alkaloidGO:004327920.029
organonitrogen compound biosynthetic processGO:1901566470.029
cortical actin cytoskeleton organizationGO:003086610.029
response to carbohydrateGO:000974330.029
regulation of intracellular protein transportGO:003315730.029
endosomal transportGO:001619720.029
cell surface receptor signaling pathwayGO:00071663250.029
camera type eye morphogenesisGO:00485931080.029
ion transmembrane transportGO:0034220910.028
nuclear importGO:005117030.028
cellular response to organic cyclic compoundGO:0071407380.028
response to amino acidGO:004320020.028
cellular response to organic substanceGO:00713101050.028
muscle structure developmentGO:00610611960.027
regulation of extrinsic apoptotic signaling pathwayGO:200123630.027
macromolecular complex assemblyGO:0065003350.027
protein importGO:001703830.027
cellular protein metabolic processGO:00442671290.026
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
localization of cellGO:00516742440.026
establishment of protein localization to organelleGO:007259440.026
cellular amine metabolic processGO:004410620.026
monovalent inorganic cation transportGO:0015672420.026
adherens junction organizationGO:003433240.026
actin filament based processGO:0030029640.025
cellular response to starvationGO:000926710.025
retina morphogenesis in camera type eyeGO:0060042790.025
peptidyl serine modificationGO:001820920.025
lipid catabolic processGO:001604240.025
protein targeting to nucleusGO:004474430.024
protein homooligomerizationGO:005126030.024
regulation of protein localization to nucleusGO:190018020.024
multicellular organismal homeostasisGO:0048871290.024
regulation of cellular carbohydrate metabolic processGO:001067540.024
regulation of cellular amine metabolic processGO:003323800.023
long chain fatty acid biosynthetic processGO:004275910.023
macromolecule localizationGO:0033036540.023
cell migrationGO:00164772370.023
phagocytosisGO:000690930.023
regulation of nucleocytoplasmic transportGO:004682220.023
negative regulation of reproductive processGO:200024230.023
regulation of nucleobase containing compound metabolic processGO:00192192500.023
negative regulation of biological processGO:00485193040.022
cellular response to extracellular stimulusGO:003166820.022
biological adhesionGO:0022610400.022
cell cycle processGO:0022402530.022
regulation of protein catabolic processGO:004217610.022
pigmentationGO:0043473850.022
hemopoiesisGO:00300971830.022
transmembrane transportGO:00550851200.022
segmentationGO:0035282970.022
rna metabolic processGO:00160702190.022
regulation of protein polymerizationGO:003227120.022
regulation of establishment of protein localization to plasma membraneGO:009000310.022
regulation of tube sizeGO:003515020.022
regulation of carbohydrate metabolic processGO:000610940.022
defense responseGO:0006952470.021
taxisGO:00423301090.021
regulation of blood pressureGO:000821710.021
positive regulation of metabolic processGO:00098931080.021
cellular ketone metabolic processGO:0042180110.021
cofactor biosynthetic processGO:0051188100.021
cell matrix adhesionGO:000716040.021
regulation of cellular amino acid metabolic processGO:000652100.021
sensory organ morphogenesisGO:00905962000.021
brain developmentGO:00074202930.021
ribonucleoside metabolic processGO:0009119110.021
protein localization to nucleusGO:003450430.021
cell cycleGO:0007049930.021
camera type eye developmentGO:00430102220.021
protein import into nucleusGO:000660630.021
circadian sleep wake cycleGO:004274520.020
regulation of cytokine productionGO:000181730.020
macromolecule modificationGO:00434121110.020
positive regulation of nucleotide catabolic processGO:003081310.020
response to glucoseGO:000974930.020
regulation of apoptotic processGO:0042981980.020
nucleobase containing compound biosynthetic processGO:00346542050.020
dicarboxylic acid metabolic processGO:004364810.020
regulation of protein import into nucleusGO:004230620.020
cellular response to steroid hormone stimulusGO:0071383310.020
circadian sleep wake cycle sleepGO:005080210.020
osteoclast differentiationGO:003031610.020
amine metabolic processGO:000930820.020
glucose homeostasisGO:004259310.020
regulation of multicellular organismal processGO:00512392770.019
determination of left right symmetryGO:00073681790.019
regulation of cellular component organizationGO:0051128860.019
establishment of protein localization to plasma membraneGO:009000210.019
regulation of multicellular organism growthGO:004001440.019
ubiquitin dependent protein catabolic processGO:000651130.019
response to inorganic substanceGO:0010035380.019
enzyme linked receptor protein signaling pathwayGO:00071671060.019
negative regulation of apoptotic processGO:0043066550.019
regulation of biosynthetic processGO:00098892500.019
regulation of bindingGO:005109830.019
modification dependent macromolecule catabolic processGO:004363230.018
phosphorylationGO:0016310690.018
Mouse
modulation by virus of host morphology or physiologyGO:001904810.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.018
negative regulation of protein kinase activityGO:000646940.018
nucleoside biosynthetic processGO:000916320.018
cellular response to topologically incorrect proteinGO:003596720.018
zymogen activationGO:003163830.018
mitochondrial transportGO:000683920.018
behaviorGO:0007610740.018
regulation of nucleotide catabolic processGO:003081120.018
cortical cytoskeleton organizationGO:003086510.018
regulation of cell matrix adhesionGO:000195210.018
regulation of cell activationGO:005086510.018
catabolic processGO:0009056320.018
lipid homeostasisGO:005508830.018
regulation of nucleoside metabolic processGO:000911820.018
response to metal ionGO:0010038340.018
negative regulation of metabolic processGO:0009892860.018
cellular protein modification processGO:00064641000.018
negative regulation of protein phosphorylationGO:000193340.018
macromolecular complex subunit organizationGO:0043933740.017
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.017
negative regulation of kinase activityGO:003367340.017
protein complex biogenesisGO:0070271300.017
cellular response to hypoxiaGO:007145610.017
regulation of muscle contractionGO:000693730.017
regulation of molecular functionGO:0065009700.017
anion transportGO:0006820380.017
amino acid transportGO:000686520.017
cellular response to biotic stimulusGO:007121630.017
response to monosaccharideGO:003428430.017
response to hexoseGO:000974630.017
muscle cell differentiationGO:00426921390.017
chemical homeostasisGO:0048878490.017
organic cyclic compound biosynthetic processGO:19013622230.017
regulation of blood vessel sizeGO:005088020.017
regulation of oocyte developmentGO:006028130.017
positive regulation of purine nucleotide catabolic processGO:003312310.017
modification dependent protein catabolic processGO:001994130.017
erythrocyte homeostasisGO:0034101550.017
regulation of signal transductionGO:00099662250.016
iron ion homeostasisGO:005507240.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
positive regulation of multicellular organismal processGO:0051240520.016
positive regulation of cytokine productionGO:000181920.016
regulation of cellular ketone metabolic processGO:001056570.016
regulation of protein metabolic processGO:0051246560.016
nucleocytoplasmic transportGO:000691340.016
hormone transportGO:000991420.016
programmed cell deathGO:00125011190.016
Human Mouse
single organism nuclear importGO:190259330.016
specification of symmetryGO:00097992040.016
sleepGO:003043110.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
alpha amino acid metabolic processGO:190160530.016
response to lipidGO:0033993600.016
synaptic transmissionGO:0007268350.016
cellular response to stressGO:0033554620.015
regulation of glucose importGO:004632410.015
Mouse
regulation of cell developmentGO:00602841000.015
developmental growthGO:00485891660.015
cellular response to lipopolysaccharideGO:007122230.015
positive regulation of signal transductionGO:0009967560.015
cellular response to oxygen levelsGO:007145310.015
protein complex subunit organizationGO:0071822460.015
regulation of sodium ion transportGO:000202820.015
regulation of purine nucleotide catabolic processGO:003312120.015
nucleoside monophosphate catabolic processGO:000912540.015
immunoglobulin mediated immune responseGO:001606430.015
regulation of cell substrate adhesionGO:001081010.015
regulation of neurogenesisGO:0050767870.015
stem cell proliferationGO:007208940.015
protein complex assemblyGO:0006461300.015
regulation of reproductive processGO:200024140.015
wound healingGO:0042060900.015
blood circulationGO:0008015870.015
negative regulation of cell deathGO:0060548600.015
axon guidanceGO:0007411860.015
synaptic vesicle transportGO:004848910.015
nucleotide metabolic processGO:0009117280.015
cellular macromolecular complex assemblyGO:0034622240.015
purine nucleoside monophosphate catabolic processGO:000912840.014
morphogenesis of an epitheliumGO:00020093330.014
positive regulation of protein polymerizationGO:003227320.014
multicellular organismal metabolic processGO:004423620.014
developmental growth involved in morphogenesisGO:0060560860.014
regulation of calcium ion transportGO:005192420.014
regulation of striated muscle contractionGO:000694220.014
cell adhesionGO:0007155400.014
positive regulation of gtpase activityGO:004354710.014
epithelial tube morphogenesisGO:00605621480.014
cellular component movementGO:00069283350.014
positive regulation of secretionGO:005104710.014
aromatic compound catabolic processGO:0019439150.014
rna biosynthetic processGO:00327741810.014
meiotic chromosome segregationGO:004513230.014
nucleic acid metabolic processGO:00903042440.014
establishment of synaptic vesicle localizationGO:009748010.014
somatic muscle developmentGO:000752540.014
response to oxygen containing compoundGO:1901700550.014
pole plasm assemblyGO:000731540.014
maternal determination of anterior posterior axis embryoGO:000835840.014
regulation of localizationGO:00328791040.014
Mouse
production of molecular mediator of immune responseGO:000244020.014
regulation of gtpase activityGO:004308720.014
autophagyGO:000691440.014
regulation of cell projection assemblyGO:006049140.013
cytoplasm organizationGO:000702840.013
negative regulation of catalytic activityGO:0043086210.013
protein modification processGO:00362111000.013
multicellular organism growthGO:003526440.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.013
carbohydrate homeostasisGO:003350010.013
intracellular transportGO:0046907320.013
cation transportGO:0006812810.013
regenerationGO:0031099910.013
regulation of protein localization to plasma membraneGO:190307610.013
tube morphogenesisGO:00352393490.013
b cell mediated immunityGO:001972430.013
single organism intracellular transportGO:1902582250.013
regulation of autophagyGO:001050630.013
cellular localizationGO:0051641970.013
regulation of inflammatory responseGO:005072720.013
response to bacteriumGO:0009617580.013
circadian sleep wake cycle processGO:002241020.013
protein secretionGO:000930610.013
antimicrobial humoral responseGO:001973020.013
response to nutrientGO:000758430.013
extracellular structure organizationGO:0043062270.013
response to steroid hormoneGO:0048545350.012
regulation of myotube differentiationGO:001083020.012
negative regulation of macromolecule metabolic processGO:0010605760.012
positive regulation of cell killingGO:003134320.012
very long chain fatty acid biosynthetic processGO:004276140.012
anterior posterior pattern specificationGO:00099521520.012
proteasomal protein catabolic processGO:001049820.012
negative regulation of synapse assemblyGO:005196420.012
negative regulation of signal transductionGO:0009968940.012
organic substance catabolic processGO:1901575280.012
phosphorus metabolic processGO:00067931090.012
Mouse
cytoskeleton organizationGO:0007010960.012
cell motilityGO:00488702440.012
regulation of circadian rhythmGO:004275240.012
endosome organizationGO:000703220.012
carbohydrate derivative metabolic processGO:1901135610.012
homeostatic processGO:00425921420.012
regulation of hormone secretionGO:004688320.012
carbohydrate derivative biosynthetic processGO:1901137430.012
synaptic vesicle localizationGO:009747910.012
actin cytoskeleton organizationGO:0030036630.012
neurological system processGO:0050877620.012
regulation of rna biosynthetic processGO:20011412130.012
positive regulation of developmental processGO:0051094500.012
lipid metabolic processGO:0006629520.012
regulation of protein ubiquitinationGO:003139630.012
purine containing compound metabolic processGO:0072521290.012
medulla oblongata developmentGO:002155040.012
nucleoside metabolic processGO:0009116110.012
b cell activationGO:004211320.012
regulation of endopeptidase activityGO:0052548230.012
cation transmembrane transportGO:0098655650.012
defense response to fungusGO:005083220.012
regulation of protein targetingGO:190353320.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
long chain fatty acid metabolic processGO:000167610.012
circulatory system processGO:0003013870.012
cell substrate junction assemblyGO:000704420.012
regulation of glucose transportGO:001082710.012
Mouse
regulation of filopodium assemblyGO:005148920.012
regulation of cardiac muscle contractionGO:005511720.011
myeloid cell differentiationGO:0030099860.011
skeletal muscle tissue developmentGO:0007519670.011
regulation of response to cytokine stimulusGO:006075930.011
regulation of peptidase activityGO:0052547230.011
angiogenesisGO:00015251580.011
positive regulation of cytoskeleton organizationGO:005149530.011
cellular catabolic processGO:0044248270.011
receptor internalizationGO:003162320.011
intracellular mrna localizationGO:000829810.011
fertilizationGO:000956630.011
anion transmembrane transportGO:0098656120.011
regionalizationGO:00030022740.011
lymphocyte proliferationGO:004665110.011
response to topologically incorrect proteinGO:003596620.011
development of primary female sexual characteristicsGO:004654540.011
positive regulation of response to stimulusGO:0048584800.011
protein phosphorylationGO:0006468470.011
cellular response to molecule of bacterial originGO:007121930.011
regulation of wound healingGO:006104120.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
cellular response to unfolded proteinGO:003462020.011
microtubule polymerization or depolymerizationGO:003110930.011
heterocycle biosynthetic processGO:00181302150.011
positive regulation of gtp catabolic processGO:003312610.011
mononuclear cell proliferationGO:003294310.011
type i interferon productionGO:003260620.011
heart processGO:0003015710.011
positive regulation of cell activationGO:005086710.011
chemosensory behaviorGO:000763510.011
cellular response to decreased oxygen levelsGO:003629410.011
cellular protein complex assemblyGO:0043623190.011
chemotaxisGO:00069351040.011
protein complex disassemblyGO:004324110.011
regulation of ion transmembrane transporter activityGO:003241220.011
cell proliferationGO:0008283800.011
regulation of circadian sleep wake cycleGO:004274910.011
response to copper ionGO:0046688130.011
ameboidal type cell migrationGO:00016671430.011
negative regulation of multi organism processGO:004390130.011
l amino acid transportGO:001580710.011
regulation of gtp catabolic processGO:003312420.011
positive regulation of cellular amine metabolic processGO:003324000.011
regulation of leukocyte mediated immunityGO:000270310.011
purine ribonucleoside monophosphate catabolic processGO:000916940.010
regulation of epithelial cell proliferationGO:005067830.010
inorganic cation transmembrane transportGO:0098662500.010
multi organism cellular processGO:004476420.010
post golgi vesicle mediated transportGO:000689210.010
regulation of heart contractionGO:0008016320.010
toll like receptor signaling pathwayGO:000222440.010
negative regulation of defense responseGO:003134820.010
establishment of organelle localizationGO:0051656450.010
er nucleus signaling pathwayGO:000698420.010
cell junction maintenanceGO:003433120.010
transcription from rna polymerase ii promoterGO:0006366800.010

hk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
disease of metabolismDOID:001466700.020
disease of cellular proliferationDOID:1456600.019
organ system cancerDOID:005068600.019
cancerDOID:16200.019
inherited metabolic disorderDOID:65500.019
musculoskeletal system diseaseDOID:1700.014
muscular diseaseDOID:008000000.014
immune system diseaseDOID:291400.013
myopathyDOID:42300.011
muscle tissue diseaseDOID:6600.011
nervous system diseaseDOID:86300.011
hematopoietic system diseaseDOID:7400.010