Danio rerio

14 known processes

p2rx3b

purinergic receptor P2X, ligand-gated ion channel, 3b

(Aliases: p2xr3.2,zP2X3.2,zgc:110486)

p2rx3b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein heterooligomerizationGO:005129110.225
Zebrafish
cation transmembrane transportGO:0098655650.192
sensory perception of chemical stimulusGO:000760630.175
Mouse
larval developmentGO:000216420.125
establishment of localizationGO:00512342440.120
single organism transportGO:00447652060.120
cell morphogenesis involved in neuron differentiationGO:00486671630.118
transmembrane transportGO:00550851200.111
axon developmentGO:00615641660.108
transmission of nerve impulseGO:0019226190.105
regulation of synaptic plasticityGO:004816710.099
Mouse
response to carbohydrateGO:000974330.097
Mouse
cell part morphogenesisGO:00329902460.093
neuron developmentGO:00486662620.091
response to chemicalGO:00422213200.087
Mouse
cell morphogenesisGO:00009022890.085
system processGO:00030081850.084
Mouse
cell projection organizationGO:00300302840.081
ion transmembrane transportGO:0034220910.080
neuromuscular synaptic transmissionGO:000727420.078
Mouse
regulation of biological qualityGO:00650082630.077
Mouse
axonogenesisGO:00074091520.075
response to external stimulusGO:00096052640.075
Mouse
cell morphogenesis involved in differentiationGO:00009041950.071
agingGO:000756820.070
smooth muscle contractionGO:000693920.067
Mouse
neuronal action potentialGO:0019228180.066
embryonic organ morphogenesisGO:00485622740.065
multicellular organismal signalingGO:0035637220.064
cation transportGO:0006812810.063
single organism localizationGO:19025782250.062
signal transductionGO:00071654550.061
neuron projection morphogenesisGO:00488121610.060
neuron projection developmentGO:00311751800.060
response to stressGO:00069502630.058
Mouse
transportGO:00068102200.055
cellular component biogenesisGO:00440851780.054
Zebrafish
neuron differentiationGO:00301823530.054
action potentialGO:0001508190.053
synaptic growth at neuromuscular junctionGO:005112420.053
central nervous system developmentGO:00074173870.052
regulation of membrane potentialGO:0042391230.051
locomotionGO:00400113130.050
generation of neuronsGO:00486993850.049
phagocytosisGO:000690930.048
cell projection morphogenesisGO:00488582440.047
regulation of developmental processGO:00507932470.046
axon guidanceGO:0007411860.044
developmental growth involved in morphogenesisGO:0060560860.042
morphogenesis of an epitheliumGO:00020093330.041
polarized epithelial cell differentiationGO:003085940.041
adult behaviorGO:003053420.041
ion transportGO:00068111140.041
extrinsic apoptotic signaling pathwayGO:009719130.040
cellular protein catabolic processGO:004425740.039
sensory organ developmentGO:00074233930.039
regulation of response to stimulusGO:00485832690.039
eye developmentGO:00016542770.039
muscle structure developmentGO:00610611960.038
growthGO:00400071740.038
cellular component morphogenesisGO:00329893360.037
regulation of gene expressionGO:00104682650.037
macromolecular complex subunit organizationGO:0043933740.037
Zebrafish
cellular response to chemical stimulusGO:00708871570.037
regulation of extrinsic apoptotic signaling pathwayGO:200123630.037
microtubule based movementGO:0007018330.036
muscle system processGO:0003012200.036
Mouse
taxisGO:00423301090.036
protein homooligomerizationGO:005126030.035
muscle cell developmentGO:00550011150.035
regulation of multicellular organism growthGO:004001440.035
embryonic organ developmentGO:00485683810.035
multicellular organism growthGO:003526440.035
cell surface receptor signaling pathwayGO:00071663250.035
cellular component movementGO:00069283350.035
neuron projection guidanceGO:0097485860.034
female sex differentiationGO:004666040.034
regulation of blood pressureGO:000821710.034
regulation of cell differentiationGO:00455951420.033
regulation of meiotic cell cycleGO:005144510.033
regulation of metabolic processGO:00192223590.033
cognitionGO:005089010.032
amine metabolic processGO:000930820.032
protein complex biogenesisGO:0070271300.032
Zebrafish
synaptic vesicle transportGO:004848910.032
chemotaxisGO:00069351040.031
regulation of neural precursor cell proliferationGO:200017730.031
chordate embryonic developmentGO:00430092710.031
regulation of macromolecule metabolic processGO:00602553170.031
regulation of bindingGO:005109830.031
regulation of nitrogen compound metabolic processGO:00511712510.031
guanosine containing compound metabolic processGO:190106840.031
ear developmentGO:00435831270.031
cellular component assemblyGO:00226071700.031
Zebrafish
regulation of cellular biosynthetic processGO:00313262450.031
autophagyGO:000691440.030
stem cell proliferationGO:007208940.030
meiotic nuclear divisionGO:000712640.030
mechanosensory behaviorGO:000763820.030
positive regulation of transportGO:005105020.030
regulation of cell communicationGO:00106462320.029
Mouse
immune system processGO:00023762410.029
blood circulationGO:0008015870.029
b cell activationGO:004211320.029
regulation of mrna processingGO:005068430.029
tube morphogenesisGO:00352393490.028
developmental growthGO:00485891660.028
regulation of multicellular organismal developmentGO:20000262230.028
positive regulation of cell cycleGO:004578730.028
positive regulation of biological processGO:00485182530.028
positive regulation of map kinase activityGO:004340630.028
hematopoietic or lymphoid organ developmentGO:00485341910.028
gtp metabolic processGO:004603940.028
regulation of protein complex assemblyGO:004325430.028
rna metabolic processGO:00160702190.028
digestive system developmentGO:00551232890.027
cell migrationGO:00164772370.027
regulation of cellular ketone metabolic processGO:001056570.027
gene expressionGO:00104672520.027
collateral sprouting in absence of injuryGO:004866940.027
cellular macromolecule biosynthetic processGO:00346452240.027
meiotic cell cycle processGO:190304630.026
inorganic cation transmembrane transportGO:0098662500.026
behaviorGO:0007610740.026
Mouse
proteolysis involved in cellular protein catabolic processGO:005160330.026
organic cyclic compound metabolic processGO:19013603010.026
nitrogen compound metabolic processGO:00068073190.026
spermatid developmentGO:000728620.026
regulation of cell activationGO:005086510.025
motor neuron axon guidanceGO:0008045230.025
compound eye developmentGO:004874920.025
response to abiotic stimulusGO:00096281220.025
Mouse
regionalizationGO:00030022740.025
regulation of signal transductionGO:00099662250.025
response to hydrogen peroxideGO:004254230.025
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.025
regenerationGO:0031099910.025
regulation of cellular macromolecule biosynthetic processGO:20001122220.025
homeostatic processGO:00425921420.025
apoptotic processGO:00069151160.024
cellular amine metabolic processGO:004410620.024
protein complex assemblyGO:0006461300.024
Zebrafish
pancreatic d cell differentiationGO:000331120.024
cellular component disassemblyGO:002241110.024
carbohydrate homeostasisGO:003350010.024
immune system developmentGO:00025201910.023
phototransductionGO:000760220.023
maternal determination of anterior posterior axis embryoGO:000835840.023
chemosensory behaviorGO:000763510.023
nerve developmentGO:0021675450.023
zymogen activationGO:003163830.023
activation of mapk activityGO:000018730.023
protein metabolic processGO:00195381830.023
negative regulation of biological processGO:00485193040.023
regulation of cytokine productionGO:000181730.023
regulation of cellular amino acid metabolic processGO:000652100.023
cell cycle arrestGO:000705010.022
heterocycle biosynthetic processGO:00181302150.022
response to endogenous stimulusGO:0009719830.022
Mouse
synaptic vesicle localizationGO:009747910.022
regulation of primary metabolic processGO:00800903110.022
cellular aromatic compound metabolic processGO:00067252950.022
centrosome organizationGO:005129710.022
multicellular organismal response to stressGO:003355520.022
Mouse
response to organic substanceGO:00100331530.022
Mouse
regulation of dendrite developmentGO:005077330.022
circulatory system processGO:0003013870.022
neurological system processGO:0050877620.022
Mouse
cytoskeleton dependent intracellular transportGO:0030705100.022
regulation of establishment of protein localizationGO:007020140.022
inorganic ion transmembrane transportGO:0098660570.021
sympathetic nervous system developmentGO:004848530.021
peristalsisGO:003043210.021
Mouse
positive regulation of cellular processGO:00485222010.021
morphogenesis of an epithelial sheetGO:0002011490.021
protein localization to plasma membraneGO:007265910.021
response to woundingGO:00096111160.021
spermatid differentiationGO:004851520.021
striated muscle tissue developmentGO:00147061100.021
heart processGO:0003015710.021
digestive tract morphogenesisGO:00485462310.021
response to monosaccharideGO:003428430.021
proteasomal protein catabolic processGO:001049820.021
regulation of alternative mrna splicing via spliceosomeGO:000038110.021
sensory organ morphogenesisGO:00905962000.021
multi organism processGO:00517041340.020
gastrulationGO:00073692080.020
female gonad developmentGO:000858540.020
positive regulation of catabolic processGO:000989640.020
regulation of autophagyGO:001050630.020
leukocyte proliferationGO:007066110.020
liver developmentGO:0001889960.020
positive regulation of notch signaling pathwayGO:004574730.020
semicircular canal developmentGO:0060872240.020
maintenance of locationGO:005123540.020
regulation of jak stat cascadeGO:004642530.020
stem cell divisionGO:001714510.020
regulation of cellular metabolic processGO:00313233200.020
cellular nitrogen compound metabolic processGO:00346412900.020
regulation of cellular component movementGO:0051270550.020
localization of cellGO:00516742440.020
purine ribonucleoside monophosphate catabolic processGO:000916940.020
regulation of stem cell proliferationGO:007209120.020
rna localizationGO:000640340.020
regulation of reproductive processGO:200024140.020
regulation of tube sizeGO:003515020.019
b cell differentiationGO:003018310.019
meiotic chromosome segregationGO:004513230.019
camera type eye developmentGO:00430102220.019
developmental cell growthGO:0048588520.019
macromolecular complex assemblyGO:0065003350.019
Zebrafish
stem cell maintenanceGO:001982740.019
response to drugGO:004249330.019
skeletal system developmentGO:00015011810.019
regulation of protein bindingGO:004339330.019
striated muscle cell developmentGO:00550021080.019
nucleic acid templated transcriptionGO:00976591810.019
regulation of peptidyl tyrosine phosphorylationGO:005073010.019
cellular macromolecule metabolic processGO:00442603910.019
tissue remodelingGO:004877140.019
ubiquitin dependent protein catabolic processGO:000651130.019
secondary metabolic processGO:001974830.019
muscle organ developmentGO:00075171010.019
modification dependent macromolecule catabolic processGO:004363230.019
nucleic acid metabolic processGO:00903042440.019
nucleobase containing compound biosynthetic processGO:00346542050.019
striated muscle cell differentiationGO:00511461290.019
establishment of protein localization to organelleGO:007259440.019
alternative mrna splicing via spliceosomeGO:000038010.019
protein polymerizationGO:005125840.019
carbohydrate biosynthetic processGO:001605110.019
locomotor rhythmGO:004547530.019
gtp catabolic processGO:000618420.018
regulation of collateral sprouting in absence of injuryGO:004869640.018
nucleoside monophosphate catabolic processGO:000912540.018
positive regulation of secretion by cellGO:190353210.018
positive regulation of secretionGO:005104710.018
cell matrix adhesionGO:000716040.018
nucleobase containing compound metabolic processGO:00061392740.018
lipid storageGO:001991510.018
positive regulation of cellular catabolic processGO:003133130.018
regulation of cellular amine metabolic processGO:003323800.018
tissue regenerationGO:0042246740.018
myotube differentiationGO:0014902450.018
response to heatGO:000940860.018
Mouse
organic cyclic compound biosynthetic processGO:19013622230.018
neuroblast proliferationGO:000740520.018
aromatic compound biosynthetic processGO:00194382170.018
macromolecule biosynthetic processGO:00090592270.018
axonal defasciculationGO:000741420.018
digestive tract developmentGO:00485652650.018
regulation of cell shapeGO:000836010.018
negative chemotaxisGO:005091910.018
rna biosynthetic processGO:00327741810.018
regulation of multicellular organismal processGO:00512392770.018
regulation of organ growthGO:004662030.018
regulation of metal ion transportGO:001095940.018
establishment of synaptic vesicle localizationGO:009748010.017
regulation of intracellular signal transductionGO:1902531570.017
modification dependent protein catabolic processGO:001994130.017
regulation of signalingGO:00230512350.017
Mouse
regulation of purine nucleotide catabolic processGO:003312120.017
response to uvGO:000941130.017
blood vessel morphogenesisGO:00485142160.017
regulation of cell deathGO:00109411030.017
intracellular signal transductionGO:0035556850.017
embryonic skeletal joint developmentGO:007249830.017
negative regulation of mapk cascadeGO:004340940.017
microtubule organizing center organizationGO:003102310.017
phasic smooth muscle contractionGO:001482110.017
Mouse
atp catabolic processGO:000620040.017
regulation of neurogenesisGO:0050767870.017
lateral inhibitionGO:004633110.017
negative regulation of kinase activityGO:003367340.017
cell substrate adhesionGO:003158940.017
retina development in camera type eyeGO:00600411460.016
regulation of neuronal synaptic plasticityGO:004816810.016
cell motilityGO:00488702440.016
wound healingGO:0042060900.016
ribonucleoside monophosphate catabolic processGO:000915840.016
positive regulation of cell adhesionGO:004578510.016
development of primary female sexual characteristicsGO:004654540.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
positive regulation of cellular amine metabolic processGO:003324000.016
actin polymerization or depolymerizationGO:000815420.016
muscle cell differentiationGO:00426921390.016
nuclear transportGO:005116940.016
positive regulation of cell activationGO:005086710.016
skeletal system morphogenesisGO:00487051020.016
production of molecular mediator of immune responseGO:000244020.016
membrane invaginationGO:001032410.016
cilium assemblyGO:0042384580.016
organelle assemblyGO:00709251100.016
lymphocyte proliferationGO:004665110.016
regulation of synapse organizationGO:005080730.016
embryo development ending in birth or egg hatchingGO:00097922710.016
phagocytosis engulfmentGO:000691110.016
monovalent inorganic cation transportGO:0015672420.016
signal transduction by p53 class mediatorGO:0072331130.016
desmosome organizationGO:000293430.016
cranial nerve developmentGO:0021545420.016
intracellular mrna localizationGO:000829810.016
negative regulation of response to stimulusGO:00485851040.016
regulation of stem cell differentiationGO:200073640.016
regulation of cell developmentGO:00602841000.016
positive regulation of cellular component biogenesisGO:004408930.016
synaptic vesicle recyclingGO:003646510.016
hormone transportGO:000991420.016
guanosine containing compound catabolic processGO:190106920.016
regulation of locomotionGO:0040012550.016
protein localization to nucleusGO:003450430.016
autonomic nervous system developmentGO:0048483190.016
regulation of reactive oxygen species metabolic processGO:200037720.015
cellular response to radiationGO:007147840.015
regulation of protein transportGO:005122330.015
brain developmentGO:00074202930.015
regulation of nucleoside metabolic processGO:000911820.015
regulation of calcium mediated signalingGO:005084810.015
cilium organizationGO:0044782710.015
trigeminal nerve developmentGO:002155930.015
muscle tissue developmentGO:00605371100.015
inner ear developmentGO:00488391260.015
protein complex subunit organizationGO:0071822460.015
Zebrafish
regulation of cell substrate adhesionGO:001081010.015
regulation of muscle contractionGO:000693730.015
embryonic skeletal joint morphogenesisGO:006027230.015
purine nucleoside monophosphate catabolic processGO:000912840.015
oocyte anterior posterior axis specificationGO:000731440.015
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.015
heart developmentGO:00075073130.015
sprouting angiogenesisGO:0002040530.015
signal transduction in absence of ligandGO:003803410.015
vasculature developmentGO:00019442780.015
exocytosisGO:000688710.015
heterocycle metabolic processGO:00464832900.015
tube closureGO:006060610.015
regulation of mrna splicing via spliceosomeGO:004802430.015
negative regulation of protein phosphorylationGO:000193340.015
gland developmentGO:00487321430.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.015
glucose homeostasisGO:004259310.014
organonitrogen compound metabolic processGO:1901564740.014
regulation of programmed cell deathGO:00430671010.014
regulation of cellular carbohydrate metabolic processGO:001067540.014
response to decreased oxygen levelsGO:0036293250.014
Mouse
anterior posterior pattern specificationGO:00099521520.014
hair cell differentiationGO:0035315320.014
synaptic transmission cholinergicGO:000727140.014
regulation of circadian rhythmGO:004275240.014
ventricular cardiac muscle tissue developmentGO:000322930.014
centrosome cycleGO:000709810.014
type b pancreatic cell developmentGO:000332340.014
catechol containing compound metabolic processGO:000971220.014
negative regulation of protein kinase activityGO:000646940.014
regulation of hormone secretionGO:004688320.014
cellular response to extracellular stimulusGO:003166820.014
cellular response to starvationGO:000926710.014
negative regulation of catabolic processGO:000989530.014
positive regulation of cytokine productionGO:000181920.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
biosynthetic processGO:00090582940.014
negative regulation of dna metabolic processGO:005105340.014
transcription from rna polymerase ii promoterGO:0006366800.014
negative regulation of cellular processGO:00485232830.014
regulation of dna replicationGO:000627530.014
regulation of rna metabolic processGO:00512522240.014
cellular carbohydrate metabolic processGO:004426240.014
heart contractionGO:0060047710.014
cilium morphogenesisGO:0060271850.014
angiogenesisGO:00015251580.014
cell growthGO:0016049570.014
cellular response to organic substanceGO:00713101050.014
single organism behaviorGO:0044708240.014
Mouse
actin filament polymerizationGO:003004120.014
regulation of transmembrane transportGO:0034762180.014
regulation of blood vessel sizeGO:005088020.014
inner ear receptor cell differentiationGO:0060113290.014
carboxylic acid metabolic processGO:0019752220.014
regulation of macromolecule biosynthetic processGO:00105562250.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
positive regulation of stem cell proliferationGO:200064810.013
larval behaviorGO:003053750.013
transcription dna templatedGO:00063511810.013
regulation of inflammatory responseGO:005072720.013
organelle fusionGO:004828430.013
response to oxygen levelsGO:0070482250.013
Mouse
organic substance biosynthetic processGO:19015762890.013
astrocyte differentiationGO:004870810.013
regulation of nucleobase containing compound metabolic processGO:00192192500.013
cellular response to external stimulusGO:007149620.013
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.013
cartilage condensationGO:000150230.013
cellular biosynthetic processGO:00442492860.013
nucleocytoplasmic transportGO:000691340.013
cellular response to nutrient levelsGO:003166920.013
proepicardium developmentGO:000334240.013
sensory system developmentGO:0048880760.013
protein oligomerizationGO:005125970.013
Zebrafish
cell cell signalingGO:0007267520.013
Mouse
response to hexoseGO:000974630.013
mononuclear cell proliferationGO:003294310.013
cellular ketone metabolic processGO:0042180110.013
regulation of wound healingGO:006104120.013
positive regulation of nucleoside metabolic processGO:004597910.013
developmental programmed cell deathGO:001062340.013
regulation of localizationGO:00328791040.013
protein dephosphorylationGO:000647030.013
phosphate containing compound metabolic processGO:00067961080.013
cellular localizationGO:0051641970.013
cellular amino acid metabolic processGO:000652070.013
positive regulation of exocytosisGO:004592110.013
regulation of cell cycleGO:0051726520.013
pronephros developmentGO:0048793690.013
macromolecular complex disassemblyGO:003298410.013
peptide transportGO:001583310.013
primary neural tube formationGO:001402010.013
cellular component assembly involved in morphogenesisGO:00109271070.013
regulation of growth rateGO:004000910.013
hormone secretionGO:004687920.013
regulation of axon extensionGO:0030516240.013
regulation of systemic arterial blood pressureGO:000307310.013
positive regulation of protein complex assemblyGO:003133420.013
oocyte maturationGO:000155640.013
b cell mediated immunityGO:001972430.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
regulation of biosynthetic processGO:00098892500.013
peptidyl threonine modificationGO:001821010.013
regulation of protein depolymerizationGO:190187910.013
pharyngeal muscle developmentGO:004328240.013
peripheral nervous system neuron developmentGO:0048935220.012
endosomal transportGO:001619720.012
determination of bilateral symmetryGO:00098552040.012
cellular protein metabolic processGO:00442671290.012
detection of chemical stimulusGO:000959340.012
nuclear importGO:005117030.012
regulation of phGO:000688530.012
establishment of epithelial cell polarityGO:009016220.012
protein secretionGO:000930610.012
medulla oblongata developmentGO:002155040.012
regulation of cell matrix adhesionGO:000195210.012
negative regulation of epithelial cell proliferationGO:005068010.012
skeletal muscle tissue developmentGO:0007519670.012
peripheral nervous system neuron differentiationGO:0048934280.012
positive regulation of dna metabolic processGO:005105410.012
sequestering of metal ionGO:005123830.012
regulation of protein complex disassemblyGO:004324410.012
membrane fusionGO:006102520.012
protein stabilizationGO:005082120.012
axon cargo transportGO:000808820.012
regulation of protein targetingGO:190353320.012
branching morphogenesis of a nerveGO:004875540.012
peptidyl lysine acetylationGO:001839420.012
regulation of glucose importGO:004632410.012
protein depolymerizationGO:005126110.012
myotube cell developmentGO:0014904350.012
phenol containing compound biosynthetic processGO:004618940.012
mesenchymal cell proliferationGO:001046310.012
regulation of nucleotide catabolic processGO:003081120.012
organelle organizationGO:00069962270.012
lamellipodium organizationGO:009758110.012
negative regulation of metabolic processGO:0009892860.012
forebrain developmentGO:0030900960.012
regulation of intracellular phGO:005145310.012
synaptic vesicle endocytosisGO:004848810.012
regulation of carbohydrate metabolic processGO:000610940.012
cell deathGO:00082191210.012
organic acid metabolic processGO:0006082310.012
regulation of cell morphogenesis involved in differentiationGO:0010769380.012
peptidyl serine phosphorylationGO:001810510.012
regulation of glial cell differentiationGO:004568540.012
regulation of protein catabolic processGO:004217610.012
cell cycleGO:0007049930.012
somatic muscle developmentGO:000752540.012
swimming behaviorGO:003626980.012
oxoacid metabolic processGO:0043436310.012
positive regulation of response to stimulusGO:0048584800.012
regulation of synaptic vesicle transportGO:190280310.012
neuron projection extensionGO:1990138450.012
nuclear migrationGO:000709730.012
cell cycle g1 s phase transitionGO:004484310.012
protein targeting to nucleusGO:004474430.011
meiosis iGO:000712710.011
peptidyl threonine phosphorylationGO:001810710.011
regulation of dna recombinationGO:000001820.011
semicircular canal morphogenesisGO:0048752180.011

p2rx3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.057
nervous system diseaseDOID:86300.020
disease of metabolismDOID:001466700.015
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.015
immune system diseaseDOID:291400.012
muscular diseaseDOID:008000000.012
musculoskeletal system diseaseDOID:1700.012
muscle tissue diseaseDOID:6600.012