Danio rerio

29 known processes

pxn

paxillin

(Aliases: wu:fw71f12)

pxn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
actin filament based processGO:0030029640.747
camera type eye morphogenesisGO:00485931080.598
cell motilityGO:00488702440.524
ameboidal type cell migrationGO:00016671430.494
cell migrationGO:00164772370.490
blood circulationGO:0008015870.454
camera type eye developmentGO:00430102220.396
cellular component movementGO:00069283350.380
muscle cell differentiationGO:00426921390.366
sensory organ developmentGO:00074233930.364
cellular component morphogenesisGO:00329893360.362
eye developmentGO:00016542770.355
retina development in camera type eyeGO:00600411460.342
actomyosin structure organizationGO:0031032530.337
cytoskeleton organizationGO:0007010960.314
vasculature developmentGO:00019442780.311
sarcomere organizationGO:0045214260.306
lens development in camera type eyeGO:0002088220.303
retina layer formationGO:0010842240.301
positive regulation of cytokine productionGO:000181920.294
neuron differentiationGO:00301823530.286
neuroblast proliferationGO:000740520.283
eye morphogenesisGO:00485921440.259
digestive system developmentGO:00551232890.251
modification dependent protein catabolic processGO:001994130.246
striated muscle cell differentiationGO:00511461290.245
nucleus localizationGO:005164780.243
retina morphogenesis in camera type eyeGO:0060042790.238
synaptic transmission cholinergicGO:000727140.230
blood vessel morphogenesisGO:00485142160.218
cellular component assembly involved in morphogenesisGO:00109271070.215
response to hexoseGO:000974630.211
organelle organizationGO:00069962270.203
ubiquitin dependent protein catabolic processGO:000651130.199
localization of cellGO:00516742440.198
generation of neuronsGO:00486993850.196
cell morphogenesisGO:00009022890.194
proteolysis involved in cellular protein catabolic processGO:005160330.193
regulation of cytokine productionGO:000181730.189
modification dependent macromolecule catabolic processGO:004363230.180
somite developmentGO:0061053960.175
single organism organelle organizationGO:19025891990.166
morphogenesis of an epitheliumGO:00020093330.165
cognitionGO:005089010.160
blood vessel developmentGO:00015682460.152
organelle assemblyGO:00709251100.151
actin cytoskeleton organizationGO:0030036630.150
response to carbohydrateGO:000974330.147
cell surface receptor signaling pathwayGO:00071663250.146
cellular protein catabolic processGO:004425740.145
mesodermal cell migrationGO:0008078120.138
regulation of protein catabolic processGO:004217610.136
regulation of cell motilityGO:2000145460.135
striated muscle cell developmentGO:00550021080.129
sprouting angiogenesisGO:0002040530.127
stem cell developmentGO:0048864820.124
gene expressionGO:00104672520.122
circulatory system processGO:0003013870.122
regulation of cell proliferationGO:0042127370.121
regulation of synapse organizationGO:005080730.120
cell morphogenesis involved in differentiationGO:00009041950.119
adherens junction organizationGO:003433240.118
response to glucoseGO:000974930.116
positive regulation of muscle organ developmentGO:004863610.114
sensory organ morphogenesisGO:00905962000.113
regulation of signalingGO:00230512350.110
locomotionGO:00400113130.107
endothelial cell migrationGO:0043542190.107
tissue migrationGO:0090130370.106
convergent extensionGO:00600261180.106
stem cell proliferationGO:007208940.106
negative regulation of synapse assemblyGO:005196420.104
muscle cell developmentGO:00550011150.102
cell migration involved in sprouting angiogenesisGO:000204280.099
vasculogenesisGO:0001570410.094
synaptic growth at neuromuscular junctionGO:005112420.094
glucose importGO:004632320.093
muscle structure developmentGO:00610611960.092
regulation of synaptic growth at neuromuscular junctionGO:000858210.091
cellular macromolecule metabolic processGO:00442603910.091
lens morphogenesis in camera type eyeGO:000208970.090
regulation of synapse assemblyGO:005196330.090
regulation of mrna processingGO:005068430.083
response to monosaccharideGO:003428430.081
regulation of primary metabolic processGO:00800903110.081
somatic muscle developmentGO:000752540.080
axon developmentGO:00615641660.079
i kappab kinase nf kappab signalingGO:000724940.079
regulation of protein kinase b signalingGO:005189680.078
positive regulation of neural precursor cell proliferationGO:200017910.075
lens fiber cell developmentGO:007030730.074
regulation of tube sizeGO:003515020.073
system processGO:00030081850.073
establishment of nucleus localizationGO:004002370.073
positive regulation of secretion by cellGO:190353210.071
single organismal cell cell adhesionGO:0016337290.071
positive regulation of protein kinase b signalingGO:005189710.070
regulation of protein complex assemblyGO:004325430.067
neuron projection developmentGO:00311751800.066
cell part morphogenesisGO:00329902460.066
regulation of mrna splicing via spliceosomeGO:004802430.066
angiogenesisGO:00015251580.065
regulation of cell migrationGO:0030334400.065
positive regulation of cell matrix adhesionGO:000195410.064
establishment or maintenance of epithelial cell apical basal polarityGO:0045197110.064
growthGO:00400071740.063
cilium morphogenesisGO:0060271850.063
negative regulation of protein kinase activityGO:000646940.062
regulation of filopodium assemblyGO:005148920.062
myofibril assemblyGO:0030239480.061
positive regulation of blood circulationGO:190352420.061
modulation by virus of host morphology or physiologyGO:001904810.060
immune system developmentGO:00025201910.060
kidney developmentGO:0001822920.058
cellular component assemblyGO:00226071700.057
positive regulation of transportGO:005105020.057
negative regulation of response to stimulusGO:00485851040.057
regulation of signal transductionGO:00099662250.057
epithelial tube morphogenesisGO:00605621480.056
cellular protein metabolic processGO:00442671290.055
positive regulation of cellular component biogenesisGO:004408930.054
positive regulation of gliogenesisGO:001401520.053
neurotransmitter transportGO:000683620.053
heart processGO:0003015710.053
mesenchyme developmentGO:00604851270.053
regulation of cell shapeGO:000836010.052
epithelial cell migrationGO:0010631250.052
carboxylic acid metabolic processGO:0019752220.052
inositol lipid mediated signalingGO:004801720.052
negative regulation of protein phosphorylationGO:000193340.051
mesenchymal cell differentiationGO:0048762870.051
stem cell differentiationGO:00488631170.050
mesoderm developmentGO:0007498880.050
regenerationGO:0031099910.050
protein importGO:001703830.050
adherens junction maintenanceGO:003433420.050
protein metabolic processGO:00195381830.049
cell migration involved in gastrulationGO:0042074790.049
cellular component biogenesisGO:00440851780.049
mitotic cell cycleGO:0000278640.049
single organism metabolic processGO:00447102170.049
response to drugGO:004249330.049
negative regulation of cell projection organizationGO:003134590.049
epidermal cell fate specificationGO:000995740.049
somitogenesisGO:0001756870.048
response to oxygen containing compoundGO:1901700550.048
regulation of blood vessel sizeGO:005088020.048
glial cell migrationGO:000834730.048
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.047
negative regulation of kinase activityGO:003367340.046
positive regulation of biological processGO:00485182530.046
positive regulation of immune effector processGO:000269930.046
cytoskeleton dependent cytokinesisGO:006164030.045
regulation of cell differentiationGO:00455951420.045
regulation of neural precursor cell proliferationGO:200017730.045
positive regulation of secretionGO:005104710.045
tube morphogenesisGO:00352393490.045
enzyme linked receptor protein signaling pathwayGO:00071671060.044
negative regulation of cell morphogenesis involved in differentiationGO:001077180.044
muscle attachmentGO:001620390.044
regulation of biological qualityGO:00650082630.044
regulation of macromolecule metabolic processGO:00602553170.043
response to amino acidGO:004320020.043
endochondral bone morphogenesisGO:006035080.043
regulation of cellular component movementGO:0051270550.042
neural retina developmentGO:0003407490.042
regulation of cellular metabolic processGO:00313233200.042
skin developmentGO:0043588540.042
negative regulation of signalingGO:0023057960.042
extracellular matrix organizationGO:0030198270.042
regulation of intracellular protein transportGO:003315730.041
negative regulation of biological processGO:00485193040.041
phagocytosisGO:000690930.041
mesenchymal cell developmentGO:0014031780.040
regulation of cell developmentGO:00602841000.040
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.040
eye photoreceptor cell differentiationGO:0001754450.040
positive regulation of cell adhesionGO:004578510.039
gastrulationGO:00073692080.039
embryonic skeletal system developmentGO:0048706970.039
positive regulation of muscle cell differentiationGO:005114910.039
establishment of protein localization to organelleGO:007259440.038
cell projection organizationGO:00300302840.038
regulation of response to stimulusGO:00485832690.038
regulation of blood coagulationGO:003019310.037
cell matrix adhesionGO:000716040.037
regulation of i kappab kinase nf kappab signalingGO:004312240.037
cellular amino acid metabolic processGO:000652070.036
negative regulation of cellular processGO:00485232830.035
cellular response to organic substanceGO:00713101050.035
negative regulation of signal transductionGO:0009968940.035
taxisGO:00423301090.035
regulation of protein ubiquitinationGO:003139630.035
neuron projection morphogenesisGO:00488121610.035
cell morphogenesis involved in neuron differentiationGO:00486671630.034
oxoacid metabolic processGO:0043436310.034
cellular response to hormone stimulusGO:0032870390.034
establishment of cell polarityGO:0030010180.034
neuron projection regenerationGO:0031102160.034
negative regulation of map kinase activityGO:004340720.033
single organism localizationGO:19025782250.033
nuclear transportGO:005116940.033
positive regulation of cell proliferationGO:0008284150.033
positive regulation of cell activationGO:005086710.032
regulation of anatomical structure sizeGO:0090066330.032
protein modification processGO:00362111000.032
water homeostasisGO:003010440.032
negative regulation of neurogenesisGO:0050768200.031
positive regulation of i kappab kinase nf kappab signalingGO:004312330.031
nitrogen compound metabolic processGO:00068073190.031
regulation of cytoplasmic transportGO:190364940.031
regulation of cellular protein catabolic processGO:190336210.031
peptide transportGO:001583310.030
regulation of mrna catabolic processGO:006101330.030
regulation of metabolic processGO:00192223590.030
neuron developmentGO:00486662620.030
stem cell maintenanceGO:001982740.030
chondrocyte developmentGO:000206340.030
regulation of stem cell differentiationGO:200073640.030
negative regulation of protein serine threonine kinase activityGO:007190120.030
organic acid metabolic processGO:0006082310.030
regulation of alternative mrna splicing via spliceosomeGO:000038110.029
lateral line system developmentGO:0048925760.029
negative regulation of protein metabolic processGO:0051248160.029
positive regulation of endothelial cell migrationGO:001059520.029
positive regulation of cell cycleGO:004578730.029
neuron migrationGO:0001764220.029
nucleic acid metabolic processGO:00903042440.029
cell projection morphogenesisGO:00488582440.029
neural crest formationGO:0014029140.029
protein targeting to nucleusGO:004474430.028
epithelium migrationGO:0090132250.028
positive regulation of muscle tissue developmentGO:190186310.028
cellular response to endogenous stimulusGO:0071495680.028
protein kinase b signalingGO:004349190.028
organic substance transportGO:0071702580.028
response to chemicalGO:00422213200.028
response to decreased oxygen levelsGO:0036293250.028
negative regulation of metabolic processGO:0009892860.027
regulation of organelle organizationGO:0033043290.027
regulation of cell migration involved in sprouting angiogenesisGO:009004930.027
regulation of organ growthGO:004662030.027
negative regulation of mapk cascadeGO:004340940.027
regulation of macromolecule biosynthetic processGO:00105562250.026
cell adhesion mediated by integrinGO:003362710.026
phosphatidylinositol mediated signalingGO:004801520.026
embryo development ending in birth or egg hatchingGO:00097922710.026
vascular process in circulatory systemGO:000301860.026
protein import into nucleusGO:000660630.026
nucleocytoplasmic transportGO:000691340.026
striated muscle tissue developmentGO:00147061100.026
cell projection assemblyGO:0030031640.026
regulation of cytoskeleton organizationGO:0051493110.026
regulation of cell projection assemblyGO:006049140.026
negative regulation of cellular component organizationGO:0051129160.026
cilium assemblyGO:0042384580.025
stem cell divisionGO:001714510.025
phosphatidylinositol 3 kinase signalingGO:001406520.025
agingGO:000756820.025
regulation of glucose transportGO:001082710.025
regulation of protein transportGO:005122330.025
regulation of establishment of protein localizationGO:007020140.025
spermatid differentiationGO:004851520.024
germ line stem cell maintenanceGO:003071820.024
digestive tract developmentGO:00485652650.024
polarized epithelial cell differentiationGO:003085940.024
cellular macromolecule biosynthetic processGO:00346452240.024
cellular protein modification processGO:00064641000.024
single organism cell adhesionGO:0098602290.024
medulla oblongata developmentGO:002155040.024
cell cycle processGO:0022402530.024
leukocyte proliferationGO:007066110.023
axon guidanceGO:0007411860.023
response to stressGO:00069502630.023
response to oxygen levelsGO:0070482250.023
maintenance of epithelial cell apical basal polarityGO:004519950.023
positive regulation of epithelial cell migrationGO:001063420.023
rna metabolic processGO:00160702190.023
axonogenesisGO:00074091520.023
digestive tract mesoderm developmentGO:000750210.023
response to external stimulusGO:00096052640.023
protein secretionGO:000930610.023
regulation of nucleocytoplasmic transportGO:004682220.023
response to hormoneGO:0009725480.022
cranial ganglion developmentGO:006155030.022
neural plate anterior posterior regionalizationGO:002199980.022
hindbrain developmentGO:0030902910.022
negative regulation of cell migrationGO:0030336170.022
negative regulation of chromosome organizationGO:200125110.022
response to nutrientGO:000758430.022
heart contractionGO:0060047710.022
regulation of protein import into nucleusGO:004230620.022
regulation of vasculature developmentGO:1901342330.022
response to organic substanceGO:00100331530.022
inner ear receptor cell fate commitmentGO:006012040.021
cell substrate adhesionGO:003158940.021
b cell activationGO:004211320.021
protein heterooligomerizationGO:005129110.021
establishment or maintenance of cell polarityGO:0007163290.021
rna stabilizationGO:004348940.021
determination of left right symmetryGO:00073681790.021
ensheathment of neuronsGO:0007272180.021
negative regulation of neuron projection developmentGO:001097790.021
protein polymerizationGO:005125840.020
positive regulation of locomotionGO:0040017140.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
brain developmentGO:00074202930.020
autophagyGO:000691440.020
regulation of carbohydrate metabolic processGO:000610940.020
action potentialGO:0001508190.020
skeletal muscle tissue developmentGO:0007519670.020
myeloid cell differentiationGO:0030099860.020
regulation of nucleotide catabolic processGO:003081120.020
regulation of locomotionGO:0040012550.020
cell cell junction organizationGO:0045216100.020
negative regulation of cell communicationGO:0010648960.020
smooth muscle contractionGO:000693920.020
nuclear migrationGO:000709730.020
nucleic acid templated transcriptionGO:00976591810.020
endocardium morphogenesisGO:000316040.020
nuclear importGO:005117030.019
cell junction organizationGO:0034330110.019
regulation of histone methylationGO:003106030.019
fatty acid biosynthetic processGO:000663340.019
digestive tract morphogenesisGO:00485462310.019
monoamine transportGO:001584410.019
leukocyte homeostasisGO:000177620.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.019
response to endogenous stimulusGO:0009719830.019
muscle cell migrationGO:001481240.019
hemopoiesisGO:00300971830.019
negative regulation of cell motilityGO:2000146170.019
negative regulation of stem cell differentiationGO:200073720.019
organic substance biosynthetic processGO:19015762890.019
regulation of protein targetingGO:190353320.019
cellular nitrogen compound metabolic processGO:00346412900.019
proteolysisGO:0006508380.018
positive regulation of glucose importGO:004632610.018
mitotic cell cycle processGO:1903047480.018
cartilage developmentGO:0051216960.018
cell junction maintenanceGO:003433120.018
heart developmentGO:00075073130.018
cellular ketone metabolic processGO:0042180110.018
fin morphogenesisGO:0033334530.018
skeletal system developmentGO:00015011810.018
microtubule based processGO:0007017600.018
positive regulation of striated muscle cell differentiationGO:005115510.018
neurotransmitter secretionGO:000726920.018
organonitrogen compound metabolic processGO:1901564740.018
hematopoietic progenitor cell differentiationGO:0002244230.018
larval developmentGO:000216420.018
cell adhesionGO:0007155400.018
cellular macromolecule catabolic processGO:0044265120.017
regulation of cellular macromolecule biosynthetic processGO:20001122220.017
long chain fatty acid metabolic processGO:000167610.017
regulation of mrna metabolic processGO:190331160.017
nuclear divisionGO:0000280230.017
alternative mrna splicing via spliceosomeGO:000038010.017
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.017
negative regulation of cell deathGO:0060548600.017
positive regulation of canonical wnt signaling pathwayGO:009026340.017
pituitary gland developmentGO:0021983160.017
cellular macromolecular complex assemblyGO:0034622240.017
establishment of localizationGO:00512342440.017
aromatic compound biosynthetic processGO:00194382170.017
synaptic transmissionGO:0007268350.017
convergent extension involved in gastrulationGO:0060027710.017
cell substrate adherens junction assemblyGO:000704510.017
cellular modified amino acid metabolic processGO:000657530.017
neural tube developmentGO:0021915620.017
interaction with hostGO:005170140.017
urogenital system developmentGO:0001655970.017
amide transportGO:0042886120.016
epithelial to mesenchymal transitionGO:0001837210.016
cellular response to chemical stimulusGO:00708871570.016
glial cell proliferationGO:001400940.016
axon ensheathmentGO:0008366180.016
transportGO:00068102200.016
regulation of erk1 and erk2 cascadeGO:007037240.016
lens fiber cell morphogenesisGO:007030930.016
cellular response to organonitrogen compoundGO:007141750.016
positive regulation of glucose transportGO:001082810.016
biological adhesionGO:0022610400.016
positive regulation of striated muscle tissue developmentGO:004584410.016
regulation of hematopoietic progenitor cell differentiationGO:190153210.016
endoderm developmentGO:0007492490.016
regulation of developmental processGO:00507932470.016
negative regulation of cellular protein metabolic processGO:0032269160.016
regulation of cell activationGO:005086510.016
multicellular organism growthGO:003526440.016
epidermal cell differentiationGO:0009913360.016
actin polymerization or depolymerizationGO:000815420.016
intracellular signal transductionGO:0035556850.016
ear morphogenesisGO:0042471640.016
nucleobase containing compound metabolic processGO:00061392740.015
interspecies interaction between organismsGO:004441940.015
regulation of cytokine biosynthetic processGO:004203510.015
somite specificationGO:0001757120.015
epithelial cell developmentGO:0002064420.015
cellular component disassemblyGO:002241110.015
regulation of protein localization to nucleusGO:190018020.015
regulation of cellular ketone metabolic processGO:001056570.015
positive regulation of immune system processGO:0002684170.015
regulation of cellular protein metabolic processGO:0032268520.015
regulation of coagulationGO:005081820.015
positive regulation of glial cell proliferationGO:006025210.015
regulation of histone h3 k9 methylationGO:005157020.015
appendage developmentGO:0048736800.015
anatomical structure arrangementGO:004853220.015
proteasomal protein catabolic processGO:001049820.015
regulation of reproductive processGO:200024140.015
negative regulation of protein kinase b signalingGO:005189820.015
myeloid leukocyte migrationGO:0097529120.015
cell fate specificationGO:0001708680.015
mesoderm morphogenesisGO:0048332510.015
regulation of apoptotic processGO:0042981980.015
symbiosis encompassing mutualism through parasitismGO:004440340.014
positive regulation of cellular catabolic processGO:003133130.014
regulation of system processGO:0044057400.014
cartilage condensationGO:000150230.014
regulation of cellular component organizationGO:0051128860.014
regulation of multicellular organism growthGO:004001440.014
pectoral fin developmentGO:0033339500.014
otic vesicle developmentGO:0071599420.014
positive regulation of macromolecule metabolic processGO:0010604930.014
negative regulation of epithelial cell proliferationGO:005068010.014
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.014
response to vitaminGO:003327330.014
immune system processGO:00023762410.014
neuronal action potentialGO:0019228180.014
protein methylationGO:0006479130.014
renal tubule morphogenesisGO:006133310.014
sensory perception of touchGO:005097520.014
negative regulation of cell developmentGO:0010721260.014
regulation of inflammatory responseGO:005072720.014
regulation of actin filament based processGO:003297090.014
biosynthetic processGO:00090582940.014
positive regulation of cell growthGO:003030750.014
regulation of nitrogen compound metabolic processGO:00511712510.014
mononuclear cell proliferationGO:003294310.014
regulation of blood circulationGO:1903522320.014
neural crest cell developmentGO:0014032620.014
small molecule metabolic processGO:0044281770.014
negative chemotaxisGO:005091910.014
hematopoietic stem cell differentiationGO:0060218200.014
phosphate containing compound metabolic processGO:00067961080.014
transmission of nerve impulseGO:0019226190.014
embryonic heart tube morphogenesisGO:00031431080.014
rna 3 end processingGO:003112320.013
cell substrate junction assemblyGO:000704420.013
viral processGO:001603210.013
regulation of cellular amino acid metabolic processGO:000652100.013
cell proliferationGO:0008283800.013
protein localization to nucleusGO:003450430.013
regulation of cell adhesionGO:0030155150.013
melanocyte differentiationGO:0030318260.013
regulation of cell morphogenesis involved in differentiationGO:0010769380.013
lymphocyte proliferationGO:004665110.013
regulation of production of molecular mediator of immune responseGO:000270010.013
negative regulation of chemotaxisGO:005092240.013
dorsal motor nucleus of vagus nerve developmentGO:002174440.013
innervationGO:006038430.013
establishment of epithelial cell polarityGO:009016220.013
histone modificationGO:0016570200.013
appendage morphogenesisGO:0035107560.013
single organism transportGO:00447652060.013
positive regulation of chromatin modificationGO:190331010.013
rna biosynthetic processGO:00327741810.013
cytokine metabolic processGO:004210710.013
embryonic organ morphogenesisGO:00485622740.013
zymogen activationGO:003163830.013
histone h3 k4 methylationGO:005156820.013
response to growth factorGO:0070848390.013
peripheral nervous system developmentGO:0007422550.013
fin developmentGO:0033333770.013
central nervous system myelin formationGO:003228910.013
establishment of localization in cellGO:0051649770.013
axis elongation involved in somitogenesisGO:009024520.013
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.013
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.013
macromolecular complex subunit organizationGO:0043933740.013
catabolic processGO:0009056320.013
hormone biosynthetic processGO:004244630.013
central nervous system neuron developmentGO:0021954290.013
response to lipidGO:0033993600.012
actin filament based movementGO:003004810.012
regulation of epithelial cell proliferationGO:005067830.012
keratinocyte differentiationGO:003021600.012
pectoral fin morphogenesisGO:0035138290.012
maintenance of locationGO:005123540.012
chordate embryonic developmentGO:00430092710.012
regulation of programmed cell deathGO:00430671010.012

pxn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
muscle tissue diseaseDOID:6600.044
muscular diseaseDOID:008000000.044
musculoskeletal system diseaseDOID:1700.044
disease of metabolismDOID:001466700.024
inherited metabolic disorderDOID:65500.024