Danio rerio

36 known processes

macf1

microtubule-actin crosslinking factor 1

(Aliases: fc46g01,si:rp71-45k5.7,wu:fc46g01)

macf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.286
neuron differentiationGO:00301823530.272
larval developmentGO:000216420.215
reproductionGO:0000003400.153
regulation of biological qualityGO:00650082630.128
locomotionGO:00400113130.112
establishment of organelle localizationGO:0051656450.104
oocyte developmentGO:0048599140.102
neuron developmentGO:00486662620.100
sexual reproductionGO:0019953360.097
cellular component morphogenesisGO:00329893360.094
regionalizationGO:00030022740.092
rna localizationGO:000640340.091
transportGO:00068102200.088
organelle localizationGO:0051640490.086
microtubule organizing center organizationGO:003102310.086
regulation of cell shapeGO:000836010.084
cell projection organizationGO:00300302840.084
protein acetylationGO:000647320.083
generation of neuronsGO:00486993850.082
fertilizationGO:000956630.082
cellular component assemblyGO:00226071700.081
cell morphogenesis involved in neuron differentiationGO:00486671630.079
axonogenesisGO:00074091520.078
neurotransmitter secretionGO:000726920.077
spermatid developmentGO:000728620.076
cell morphogenesis involved in differentiationGO:00009041950.076
establishment of protein localization to organelleGO:007259440.076
protein acylationGO:004354330.075
embryo development ending in birth or egg hatchingGO:00097922710.074
cellular process involved in reproduction in multicellular organismGO:0022412280.074
cell part morphogenesisGO:00329902460.074
synaptic vesicle localizationGO:009747910.074
centrosome organizationGO:005129710.073
stem cell maintenanceGO:001982740.071
establishment of rna localizationGO:005123630.071
cellular component biogenesisGO:00440851780.067
synaptic vesicle transportGO:004848910.065
axon developmentGO:00615641660.065
positive regulation of biological processGO:00485182530.064
establishment of synaptic vesicle localizationGO:009748010.063
nucleic acid transportGO:005065720.063
sensory organ developmentGO:00074233930.063
cellular aromatic compound metabolic processGO:00067252950.062
dorsal ventral pattern formationGO:00099531250.062
cellular macromolecule metabolic processGO:00442603910.061
regulation of bindingGO:005109830.061
single organism localizationGO:19025782250.060
cellular nitrogen compound metabolic processGO:00346412900.059
establishment of localizationGO:00512342440.058
localization of cellGO:00516742440.057
somatic muscle developmentGO:000752540.057
gamete generationGO:0007276330.057
neurotransmitter transportGO:000683620.056
multicellular organismal reproductive processGO:0048609350.055
response to external stimulusGO:00096052640.055
multi organism reproductive processGO:0044703360.054
organelle assemblyGO:00709251100.053
multi organism processGO:00517041340.053
peptidyl lysine acetylationGO:001839420.052
heterocycle metabolic processGO:00464832900.051
nuclear transportGO:005116940.050
internal peptidyl lysine acetylationGO:001839320.050
cytokinesisGO:000091030.049
regulation of nitrogen compound metabolic processGO:00511712510.048
regulation of cell activationGO:005086510.048
taxisGO:00423301090.048
neuron projection developmentGO:00311751800.048
neuron projection morphogenesisGO:00488121610.047
cell surface receptor signaling pathwayGO:00071663250.047
positive regulation of catabolic processGO:000989640.047
axon guidanceGO:0007411860.046
positive regulation of mrna metabolic processGO:190331320.046
single organism transportGO:00447652060.046
regulation of reproductive processGO:200024140.046
regulation of localizationGO:00328791040.046
response to chemicalGO:00422213200.045
meiotic nuclear divisionGO:000712640.045
nitrogen compound metabolic processGO:00068073190.044
lamellipodium organizationGO:009758110.044
reproductive processGO:0022414400.044
developmental maturationGO:0021700340.044
regulation of rna metabolic processGO:00512522240.043
spermatid differentiationGO:004851520.043
exocytosisGO:000688710.043
organic substance biosynthetic processGO:19015762890.043
mrna transportGO:005102820.043
meiotic cell cycle processGO:190304630.043
organelle fusionGO:004828430.043
embryonic skeletal system morphogenesisGO:0048704930.041
regulation of primary metabolic processGO:00800903110.041
regulation of oocyte developmentGO:006028130.040
aromatic compound biosynthetic processGO:00194382170.039
regulation of biosynthetic processGO:00098892500.039
single organism organelle organizationGO:19025891990.039
organic cyclic compound metabolic processGO:19013603010.039
rna transportGO:005065820.039
regulation of multicellular organism growthGO:004001440.039
anterior posterior pattern specificationGO:00099521520.039
regulation of nucleic acid templated transcriptionGO:19035062130.038
skeletal system developmentGO:00015011810.038
olfactory bulb developmentGO:002177240.038
maintenance of locationGO:005123540.038
ribonucleoside monophosphate catabolic processGO:000915840.038
internal protein amino acid acetylationGO:000647520.038
response to organic substanceGO:00100331530.037
purine nucleoside monophosphate catabolic processGO:000912840.037
oocyte anterior posterior axis specificationGO:000731440.036
negative regulation of developmental processGO:0051093650.036
deathGO:00162651210.036
cellular component movementGO:00069283350.036
regulation of cell communicationGO:00106462320.035
cytoplasm organizationGO:000702840.035
cell migrationGO:00164772370.035
protein polymerizationGO:005125840.035
regulation of stem cell differentiationGO:200073640.035
cell deathGO:00082191210.035
nucleoside monophosphate catabolic processGO:000912540.035
chordate embryonic developmentGO:00430092710.034
meiotic chromosome segregationGO:004513230.034
cell projection morphogenesisGO:00488582440.033
regulation of organelle assemblyGO:190211540.033
guanosine containing compound metabolic processGO:190106840.033
neuron projection guidanceGO:0097485860.032
positive regulation of cellular catabolic processGO:003133130.032
multicellular organism reproductionGO:0032504350.032
multicellular organism growthGO:003526440.032
regulation of alternative mrna splicing via spliceosomeGO:000038110.031
regulation of dna recombinationGO:000001820.031
regulation of response to nutrient levelsGO:003210710.031
regulation of gtp catabolic processGO:003312420.031
cellular localizationGO:0051641970.031
cellular ketone metabolic processGO:0042180110.031
rna metabolic processGO:00160702190.031
nuclear migrationGO:000709730.031
actin filament polymerizationGO:003004120.031
hormone secretionGO:004687920.031
glial cell proliferationGO:001400940.031
macromolecule biosynthetic processGO:00090592270.031
somatic stem cell maintenanceGO:003501910.031
maternal determination of anterior posterior axis embryoGO:000835840.030
organelle organizationGO:00069962270.030
regulation of establishment of protein localizationGO:007020140.030
signal transductionGO:00071654550.030
homeostatic processGO:00425921420.030
negative regulation of metabolic processGO:0009892860.030
pole plasm assemblyGO:000731540.030
atp catabolic processGO:000620040.030
purine ribonucleoside monophosphate catabolic processGO:000916940.029
axis specificationGO:0009798430.029
phagocytosisGO:000690930.029
inner ear developmentGO:00488391260.029
chemotaxisGO:00069351040.029
centrosome cycleGO:000709810.029
regulation of protein transportGO:005122330.029
regulation of nucleobase containing compound metabolic processGO:00192192500.028
single fertilizationGO:000733830.028
establishment of localization in cellGO:0051649770.028
lamellipodium assemblyGO:003003210.028
olfactory lobe developmentGO:002198840.028
developmental growthGO:00485891660.028
eye developmentGO:00016542770.028
regulation of cellular amino acid metabolic processGO:000652100.028
negative regulation of biological processGO:00485193040.028
negative regulation of reproductive processGO:200024230.027
oocyte constructionGO:000730850.027
membrane fusionGO:006102520.027
cellular biosynthetic processGO:00442492860.027
rna biosynthetic processGO:00327741810.027
cellular component disassemblyGO:002241110.027
brain developmentGO:00074202930.027
system processGO:00030081850.027
protein complex disassemblyGO:004324110.027
cell morphogenesisGO:00009022890.027
spindle assemblyGO:005122520.027
protein import into nucleusGO:000660630.027
leukocyte proliferationGO:007066110.026
regulation of protein complex assemblyGO:004325430.026
synaptic vesicle endocytosisGO:004848810.026
rna 3 end processingGO:003112320.026
covalent chromatin modificationGO:0016569200.026
organonitrogen compound metabolic processGO:1901564740.026
multicellular organismal homeostasisGO:0048871290.026
hormone transportGO:000991420.025
vacuolar transportGO:000703420.025
positive regulation of cellular component biogenesisGO:004408930.025
oogenesisGO:0048477140.025
single organism nuclear importGO:190259330.025
endosomal transportGO:001619720.025
protein metabolic processGO:00195381830.025
limb bud formationGO:006017420.025
regulation of multicellular organismal processGO:00512392770.025
ph reductionGO:004585110.025
regulation of intracellular phGO:005145310.025
regulation of cellular amine metabolic processGO:003323800.025
golgi vesicle transportGO:004819330.025
nucleocytoplasmic transportGO:000691340.025
microtubule based processGO:0007017600.025
spermatogenesisGO:000728370.024
meiosis iiGO:000713510.024
primary neural tube formationGO:001402010.024
regulation of metabolic processGO:00192223590.024
cytoskeleton dependent cytokinesisGO:006164030.024
synaptic transmissionGO:0007268350.024
programmed cell deathGO:00125011190.024
organic substance transportGO:0071702580.024
apoptotic processGO:00069151160.023
cellular nitrogen compound biosynthetic processGO:00442712180.023
gtp metabolic processGO:004603940.023
muscle structure developmentGO:00610611960.023
regulation of cellular ketone metabolic processGO:001056570.023
regulation of cytokine productionGO:000181730.023
negative regulation of cellular processGO:00485232830.023
cellular component assembly involved in morphogenesisGO:00109271070.023
lipid storageGO:001991510.023
positive regulation of gtp catabolic processGO:003312610.023
positive regulation of cell cycleGO:004578730.023
regulation of cytoplasmic transportGO:190364940.023
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.023
nuclear exportGO:005116810.022
negative regulation of chromosome organizationGO:200125110.022
cellular monovalent inorganic cation homeostasisGO:003000420.022
cellular amine metabolic processGO:004410620.022
endocrine hormone secretionGO:006098620.022
homeostasis of number of cells within a tissueGO:004887340.022
nucleobase containing compound biosynthetic processGO:00346542050.022
neuron neuron synaptic transmissionGO:000727010.022
actin filament based movementGO:003004810.021
regulation of transcription dna templatedGO:00063552130.021
rna polyadenylationGO:004363120.021
gtp catabolic processGO:000618420.021
organic cyclic compound biosynthetic processGO:19013622230.021
regulation of cellular biosynthetic processGO:00313262450.021
regulation of mrna processingGO:005068430.020
regulation of signal transductionGO:00099662250.020
intracellular mrna localizationGO:000829810.020
regulation of cell developmentGO:00602841000.020
hematopoietic or lymphoid organ developmentGO:00485341910.020
embryonic limb morphogenesisGO:003032620.020
small gtpase mediated signal transductionGO:000726480.020
mitotic cytokinesisGO:000028130.020
negative regulation of chromatin modificationGO:190330910.020
regulation of phGO:000688530.020
neuromuscular process controlling balanceGO:005088530.020
cell cell recognitionGO:000998810.020
cytoskeleton organizationGO:0007010960.020
microtubule cytoskeleton organization involved in mitosisGO:190285010.020
multicellular organismal signalingGO:0035637220.020
regulation of developmental processGO:00507932470.020
regulation of cellular component organizationGO:0051128860.019
mononuclear cell proliferationGO:003294310.019
positive regulation of cytosolic calcium ion concentrationGO:000720440.019
regulation of dendrite developmentGO:005077330.019
biosynthetic processGO:00090582940.019
cellular carbohydrate metabolic processGO:004426240.019
positive regulation of translationGO:004572710.019
male meiosisGO:000714020.019
amine metabolic processGO:000930820.019
response to hexoseGO:000974630.019
regulation of cell substrate adhesionGO:001081010.019
nucleobase containing compound transportGO:001593120.019
regulation of protein polymerizationGO:003227120.019
positive regulation of nitrogen compound metabolic processGO:0051173690.019
protein localization to nucleusGO:003450430.019
neuroblast differentiationGO:001401610.019
regulation of dendrite morphogenesisGO:004881430.019
regulation of organelle organizationGO:0033043290.019
action potentialGO:0001508190.019
response to carbohydrateGO:000974330.019
cognitionGO:005089010.018
nucleobase containing small molecule metabolic processGO:0055086320.018
mrna 3 end processingGO:003112420.018
aromatic compound catabolic processGO:0019439150.018
regulation of cellular phGO:003064110.018
protein importGO:001703830.018
cellular response to external stimulusGO:007149620.018
positive regulation of purine nucleotide catabolic processGO:003312310.018
protein targeting to vacuoleGO:000662310.018
central nervous system developmentGO:00074173870.018
regulation of anatomical structure morphogenesisGO:00226031300.018
nitrogen compound transportGO:0071705230.018
positive regulation of nucleotide catabolic processGO:003081310.018
cellular macromolecule biosynthetic processGO:00346452240.018
cellular response to nutrient levelsGO:003166920.018
regulation of protein depolymerizationGO:190187910.018
regulation of intracellular protein transportGO:003315730.018
transcription from rna polymerase ii promoterGO:0006366800.018
regulation of protein bindingGO:004339330.018
negative regulation of histone modificationGO:003105710.018
negative regulation of cell communicationGO:0010648960.018
positive regulation of transportGO:005105020.018
positive regulation of apoptotic signaling pathwayGO:200123510.018
transcription dna templatedGO:00063511810.018
histone demethylationGO:001657720.018
astral microtubule organizationGO:003095310.018
ear developmentGO:00435831270.018
stem cell differentiationGO:00488631170.017
regulation of nucleocytoplasmic transportGO:004682220.017
regulation of rna biosynthetic processGO:20011412130.017
regulation of protein complex disassemblyGO:004324410.017
epithelial cell morphogenesisGO:000338220.017
positive regulation of canonical wnt signaling pathwayGO:009026340.017
regulation of myelinationGO:003164110.017
adult behaviorGO:003053420.017
female sex differentiationGO:004666040.017
regulation of macromolecule metabolic processGO:00602553170.017
regulation of response to stimulusGO:00485832690.017
positive regulation of cell divisionGO:005178120.017
neurological system processGO:0050877620.017
actin cytoskeleton organizationGO:0030036630.017
endosome organizationGO:000703220.017
peptide transportGO:001583310.017
actin polymerization or depolymerizationGO:000815420.017
heterocycle biosynthetic processGO:00181302150.017
regulation of signalingGO:00230512350.016
regulation of nucleoside metabolic processGO:000911820.016
organic acid metabolic processGO:0006082310.016
regulation of macromolecule biosynthetic processGO:00105562250.016
nuclear importGO:005117030.016
regulation of cell proliferation involved in heart morphogenesisGO:200013620.016
segmentationGO:0035282970.016
zymogen activationGO:003163830.016
cellular response to extracellular stimulusGO:003166820.016
skeletal system morphogenesisGO:00487051020.016
negative regulation of gliogenesisGO:001401410.016
gene expressionGO:00104672520.016
positive regulation of nucleobase containing compound metabolic processGO:0045935690.016
cellular amino acid metabolic processGO:000652070.016
negative regulation of dna metabolic processGO:005105340.016
nucleobase containing compound metabolic processGO:00061392740.016
striated muscle cell developmentGO:00550021080.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
lymphocyte proliferationGO:004665110.016
negative regulation of intracellular protein transportGO:009031730.016
regulation of nucleotide catabolic processGO:003081120.015
meiotic spindle organizationGO:000021210.015
protein demethylationGO:000648220.015
nucleic acid metabolic processGO:00903042440.015
embryonic skeletal system developmentGO:0048706970.015
negative regulation of intracellular transportGO:003238730.015
tissue homeostasisGO:0001894250.015
regulation of cell maturationGO:190342910.015
germ cell developmentGO:0007281220.015
protein secretionGO:000930610.015
carbohydrate biosynthetic processGO:001605110.015
regulation of autophagyGO:001050630.015
positive regulation of mrna processingGO:005068510.015
compound eye developmentGO:004874920.015
ras protein signal transductionGO:000726570.015
post golgi vesicle mediated transportGO:000689210.015
positive regulation of cell activationGO:005086710.015
negative regulation of secretionGO:005104820.015
development of primary female sexual characteristicsGO:004654540.015
guanosine containing compound catabolic processGO:190106920.015
regulation of cellular metabolic processGO:00313233200.015
synaptic vesicle recyclingGO:003646510.015
rna processingGO:0006396250.015
female gonad developmentGO:000858540.015
transmission of nerve impulseGO:0019226190.015
regulation of embryonic developmentGO:0045995470.015
germ line stem cell maintenanceGO:003071820.015
protein targeting to nucleusGO:004474430.015
negative regulation of epithelial cell proliferationGO:005068010.015
single organism membrane fusionGO:004480120.015
regulation of stem cell proliferationGO:007209120.015
protein dealkylationGO:000821420.015
regulation of response to extracellular stimulusGO:003210410.015
locomotor rhythmGO:004547530.014
cellular response to starvationGO:000926710.014
regulation of neurological system processGO:003164420.014
regulation of sodium ion transportGO:000202820.014
macromolecular complex assemblyGO:0065003350.014
digestive system developmentGO:00551232890.014
embryonic organ morphogenesisGO:00485622740.014
regulation of multicellular organismal developmentGO:20000262230.014
somatic cell dna recombinationGO:001644410.014
regulation of wound healingGO:006104120.014
ameboidal type cell migrationGO:00016671430.014
positive regulation of nucleoside metabolic processGO:004597910.014
hemopoiesisGO:00300971830.014
somitogenesisGO:0001756870.014
oocyte differentiationGO:0009994140.014
positive regulation of cytoskeleton organizationGO:005149530.014
cellular response to organic cyclic compoundGO:0071407380.014
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.014
positive regulation of mesenchymal cell proliferationGO:000205310.014
chromosome organization involved in meiosisGO:007019210.014
cellular response to hypoxiaGO:007145610.014
positive regulation of neuron deathGO:190121610.014
mitochondrion organizationGO:000700540.014
photoreceptor cell differentiationGO:0046530550.014
cellular nitrogen compound catabolic processGO:0044270150.014
rna catabolic processGO:000640170.014
protein localization to plasma membraneGO:007265910.014
mrna polyadenylationGO:000637820.013
histone lysine demethylationGO:007007620.013
positive regulation of map kinase activityGO:004340630.013
regulation of gtpase activityGO:004308720.013
endosome to lysosome transportGO:000833310.013
wound healingGO:0042060900.013
heterocycle catabolic processGO:0046700150.013
intracellular transportGO:0046907320.013
macroautophagyGO:001623610.013
cardiac cell fate commitmentGO:006091110.013
cellular protein complex disassemblyGO:004362410.013
regulation of muscle contractionGO:000693730.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
amino acid transportGO:000686520.013
regulation of purine nucleotide catabolic processGO:003312120.013
immune system processGO:00023762410.013
nucleic acid templated transcriptionGO:00976591810.013
gastrulationGO:00073692080.013
sarcomere organizationGO:0045214260.013
entrainment of circadian clockGO:000964920.013
synaptic growth at neuromuscular junctionGO:005112420.013
regulation of epithelial cell proliferationGO:005067830.013
negative regulation of response to stimulusGO:00485851040.013
regulation of microtubule cytoskeleton organizationGO:007050730.013
negative regulation of macromolecule metabolic processGO:0010605760.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
anatomical structure homeostasisGO:0060249360.013
morphogenesis of an epithelial foldGO:006057110.013
activation of mapk activityGO:000018730.013
aorta morphogenesisGO:003590930.013
regulation of protein targetingGO:190353320.013
regulation of endocrine processGO:004406020.013
microtubule cytoskeleton organizationGO:0000226330.013
anion transportGO:0006820380.013
negative regulation of protein transportGO:005122430.013
developmental process involved in reproductionGO:0003006270.012
regulation of circadian rhythmGO:004275240.012
female meiotic divisionGO:000714320.012
chromosome organizationGO:0051276310.012
positive regulation of secretionGO:005104710.012
cell cell signalingGO:0007267520.012
cell substrate adhesionGO:003158940.012
regulation of cellular response to growth factor stimulusGO:0090287350.012
aorta developmentGO:003590440.012
negative regulation of signal transductionGO:0009968940.012
endomembrane system organizationGO:0010256130.012
positive regulation of muscle cell differentiationGO:005114910.012
establishment of protein localization to vacuoleGO:007266610.012
macromolecular complex disassemblyGO:003298410.012
negative regulation of protein localization to nucleusGO:190018120.012
intracellular signal transductionGO:0035556850.012
regulation of ras gtpase activityGO:003231820.012
ribonucleoprotein complex assemblyGO:002261850.012
negative regulation of translationGO:001714810.012
protein depolymerizationGO:005126110.012
negative regulation of multi organism processGO:004390130.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
regulation of synapse organizationGO:005080730.012
regulation of sodium ion transmembrane transportGO:190230510.012
head developmentGO:00603223030.012
negative regulation of signalingGO:0023057960.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
extrinsic apoptotic signaling pathwayGO:009719130.012
erythrocyte homeostasisGO:0034101550.012
stem cell divisionGO:001714510.012
negative regulation of leukocyte differentiationGO:190210610.012
alternative mrna splicing via spliceosomeGO:000038010.011
neuronal action potentialGO:0019228180.011
mesenchymal cell proliferationGO:001046310.011
positive regulation of dna metabolic processGO:005105410.011
regulation of synaptic plasticityGO:004816710.011
macromolecule localizationGO:0033036540.011
oxoacid metabolic processGO:0043436310.011
sleepGO:003043110.011
camera type eye developmentGO:00430102220.011
cardiac atrium morphogenesisGO:000320920.011
digestive tract developmentGO:00485652650.011
negative regulation of kinase activityGO:003367340.011
striated muscle cell differentiationGO:00511461290.011
positive regulation of myeloid cell differentiationGO:004563920.011
single organism reproductive processGO:0044702400.011
regulation of mesenchymal cell proliferationGO:001046410.011
regulation of mrna catabolic processGO:006101330.011
mitotic metaphase plate congressionGO:000708010.011
negative regulation of cytoplasmic transportGO:190365020.011
long chain fatty acid transportGO:001590910.011
regulation of hormone secretionGO:004688320.011
stem cell fate commitmentGO:004886510.011
regulation of neuronal synaptic plasticityGO:004816810.011
polarized epithelial cell differentiationGO:003085940.011
regulation of membrane potentialGO:0042391230.011
regulation of chromosome segregationGO:005198310.011
regulation of protein import into nucleusGO:004230620.011
ovulation cycleGO:004269820.011
regulation of cytokine mediated signaling pathwayGO:000195930.011

macf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.082
nervous system diseaseDOID:86300.071
cancerDOID:16200.029
disease of cellular proliferationDOID:1456600.029
organ system cancerDOID:005068600.029
musculoskeletal system diseaseDOID:1700.014