Danio rerio

18 known processes

crk

v-crk sarcoma virus CT10 oncogene homolog (avian)

(Aliases: wu:fc05a01,zgc:100936,fi19g05,wu:fc54a04,fb34h10,wu:fi19g05,fc05a01,wu:fb34h10)

crk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle cell differentiationGO:00426921390.110
signal transductionGO:00071654550.099
Human Mouse Rat Fly
cellular macromolecule metabolic processGO:00442603910.095
striated muscle cell differentiationGO:00511461290.082
muscle structure developmentGO:00610611960.076
agingGO:000756820.076
larval developmentGO:000216420.072
regulation of establishment of protein localizationGO:007020140.065
regulation of signal transductionGO:00099662250.064
Human Mouse Rat Fly
maintenance of locationGO:005123540.062
tube morphogenesisGO:00352393490.057
regulation of signalingGO:00230512350.055
Human Mouse Rat Fly
phagocytosisGO:000690930.055
Fly
immune system processGO:00023762410.053
localization of cellGO:00516742440.053
Fly
modification dependent protein catabolic processGO:001994130.052
positive regulation of cellular component biogenesisGO:004408930.050
positive regulation of transportGO:005105020.050
cellular protein catabolic processGO:004425740.049
modification dependent macromolecule catabolic processGO:004363230.048
nuclear transportGO:005116940.048
single organism localizationGO:19025782250.046
Fly
cellular component movementGO:00069283350.046
Fly
positive regulation of cell cycleGO:004578730.045
multicellular organism growthGO:003526440.045
digestive system developmentGO:00551232890.044
blood vessel developmentGO:00015682460.044
gastrulationGO:00073692080.044
regulation of cellular metabolic processGO:00313233200.043
Human Fly
myotube differentiationGO:0014902450.043
immune system developmentGO:00025201910.043
regulation of protein transportGO:005122330.043
regulation of multicellular organismal processGO:00512392770.043
nucleocytoplasmic transportGO:000691340.043
heart developmentGO:00075073130.042
heterocycle metabolic processGO:00464832900.042
Human
proteolysis involved in cellular protein catabolic processGO:005160330.042
cell migrationGO:00164772370.041
Fly
protein localization to nucleusGO:003450430.041
protein import into nucleusGO:000660630.041
response to chemicalGO:00422213200.041
establishment of localizationGO:00512342440.040
Fly
regulation of bindingGO:005109830.039
digestive tract morphogenesisGO:00485462310.039
cellular response to external stimulusGO:007149620.039
protein targeting to nucleusGO:004474430.039
vasculature developmentGO:00019442780.038
single organism nuclear importGO:190259330.037
regulation of multicellular organism growthGO:004001440.037
establishment of protein localization to organelleGO:007259440.037
regulation of response to stimulusGO:00485832690.037
Human Mouse Rat Fly
cell motilityGO:00488702440.036
Fly
regulation of intracellular protein transportGO:003315730.036
embryonic organ developmentGO:00485683810.035
stem cell maintenanceGO:001982740.035
ubiquitin dependent protein catabolic processGO:000651130.035
regulation of multicellular organismal developmentGO:20000262230.035
lipid storageGO:001991510.035
locomotionGO:00400113130.035
Fly
regulation of nitrogen compound metabolic processGO:00511712510.035
Human
nucleobase containing compound metabolic processGO:00061392740.034
Human
cellular biosynthetic processGO:00442492860.034
cellular amine metabolic processGO:004410620.034
cellular response to chemical stimulusGO:00708871570.034
positive regulation of catabolic processGO:000989640.034
cell morphogenesisGO:00009022890.034
guanosine containing compound metabolic processGO:190106840.034
Human
morphogenesis of an epitheliumGO:00020093330.033
positive regulation of cellular catabolic processGO:003133130.033
regulation of protein targetingGO:190353320.033
nuclear importGO:005117030.033
regulation of meiotic cell cycleGO:005144510.033
cell part morphogenesisGO:00329902460.032
single organism transportGO:00447652060.032
Fly
regulation of cellular biosynthetic processGO:00313262450.032
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.032
transportGO:00068102200.032
Fly
neuron differentiationGO:00301823530.032
organic cyclic compound metabolic processGO:19013603010.031
Human
gland developmentGO:00487321430.031
regulation of metabolic processGO:00192223590.031
Human Fly
regulation of transcription dna templatedGO:00063552130.031
sensory organ developmentGO:00074233930.031
amine metabolic processGO:000930820.031
cellular aromatic compound metabolic processGO:00067252950.030
Human
cellular nitrogen compound metabolic processGO:00346412900.030
Human
regulation of developmental processGO:00507932470.030
digestive tract developmentGO:00485652650.030
nitrogen compound metabolic processGO:00068073190.030
Human
cell substrate adhesionGO:003158940.030
negative regulation of biological processGO:00485193040.029
rna metabolic processGO:00160702190.029
regulation of cellular amino acid metabolic processGO:000652100.029
regulation of cellular amine metabolic processGO:003323800.029
negative regulation of protein phosphorylationGO:000193340.029
protein importGO:001703830.029
regionalizationGO:00030022740.029
regulation of protein localization to nucleusGO:190018020.029
hemopoiesisGO:00300971830.029
macromolecule biosynthetic processGO:00090592270.028
mitochondrion organizationGO:000700540.028
regulation of protein import into nucleusGO:004230620.028
regulation of cellular ketone metabolic processGO:001056570.028
cell cycle g1 s phase transitionGO:004484310.028
cellular component morphogenesisGO:00329893360.028
regulation of biological qualityGO:00650082630.028
regulation of macromolecule metabolic processGO:00602553170.028
guanosine containing compound catabolic processGO:190106920.028
Human
cell projection morphogenesisGO:00488582440.027
negative regulation of cellular processGO:00485232830.027
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.027
Fly
germ line stem cell maintenanceGO:003071820.027
cognitionGO:005089010.027
gene expressionGO:00104672520.027
blood vessel morphogenesisGO:00485142160.026
aromatic compound biosynthetic processGO:00194382170.026
positive regulation of biological processGO:00485182530.026
Mouse Fly
programmed cell deathGO:00125011190.026
cellular nitrogen compound biosynthetic processGO:00442712180.026
myoblast fusionGO:0007520100.026
organelle organizationGO:00069962270.026
Human Mouse
ameboidal type cell migrationGO:00016671430.026
Fly
angiogenesisGO:00015251580.026
gtp metabolic processGO:004603940.026
Human
meiotic nuclear divisionGO:000712640.026
regulation of primary metabolic processGO:00800903110.025
Human
cell surface receptor signaling pathwayGO:00071663250.025
Human
regulation of macromolecule biosynthetic processGO:00105562250.025
g1 s transition of mitotic cell cycleGO:000008210.025
response to organic substanceGO:00100331530.025
cellular response to lipopolysaccharideGO:007122230.025
nucleic acid templated transcriptionGO:00976591810.025
positive regulation of cytokine productionGO:000181920.025
gtp catabolic processGO:000618420.024
Human
cell morphogenesis involved in differentiationGO:00009041950.024
single organism organelle organizationGO:19025891990.024
Human Mouse
positive regulation of stress activated mapk cascadeGO:003287430.024
Fly
regulation of nucleoside metabolic processGO:000911820.024
Human
cellular macromolecule biosynthetic processGO:00346452240.024
organic substance biosynthetic processGO:19015762890.024
cellular response to biotic stimulusGO:007121630.024
cell projection organizationGO:00300302840.024
central nervous system developmentGO:00074173870.024
cellular amino acid metabolic processGO:000652070.024
chordate embryonic developmentGO:00430092710.024
enzyme linked receptor protein signaling pathwayGO:00071671060.024
Human
eye developmentGO:00016542770.024
regulation of cell shapeGO:000836010.023
cell migration involved in gastrulationGO:0042074790.023
proteasomal protein catabolic processGO:001049820.023
peptidyl serine phosphorylationGO:001810510.023
regulation of cytokine productionGO:000181730.023
response to external stimulusGO:00096052640.023
regulation of nucleocytoplasmic transportGO:004682220.023
hematopoietic or lymphoid organ developmentGO:00485341910.023
head developmentGO:00603223030.023
protein metabolic processGO:00195381830.023
regulation of purine nucleotide catabolic processGO:003312120.023
Human
regulation of nucleotide catabolic processGO:003081120.023
Human
regulation of synapse assemblyGO:005196330.023
biosynthetic processGO:00090582940.022
embryo development ending in birth or egg hatchingGO:00097922710.022
organic acid metabolic processGO:0006082310.022
regulation of gtp catabolic processGO:003312420.022
Human
regulation of protein catabolic processGO:004217610.022
extrinsic apoptotic signaling pathwayGO:009719130.022
developmental growthGO:00485891660.022
nucleobase containing compound biosynthetic processGO:00346542050.022
positive regulation of cellular processGO:00485222010.022
Mouse Fly
cellular response to extracellular stimulusGO:003166820.022
regulation of nucleobase containing compound metabolic processGO:00192192500.022
Human
stem cell proliferationGO:007208940.022
regulation of cell differentiationGO:00455951420.022
brain developmentGO:00074202930.022
camera type eye developmentGO:00430102220.021
embryonic organ morphogenesisGO:00485622740.021
axon developmentGO:00615641660.021
regulation of cell communicationGO:00106462320.021
Human Mouse Rat Fly
deathGO:00162651210.021
carboxylic acid metabolic processGO:0019752220.021
nucleic acid metabolic processGO:00903042440.021
positive regulation of cellular amine metabolic processGO:003324000.021
organic cyclic compound biosynthetic processGO:19013622230.021
response to stressGO:00069502630.021
Fly
small molecule metabolic processGO:0044281770.021
Human
regulation of cell deathGO:00109411030.021
mesenchyme developmentGO:00604851270.021
single organism metabolic processGO:00447102170.021
Human Fly
membrane invaginationGO:001032410.020
Fly
cell deathGO:00082191210.020
regulation of rna biosynthetic processGO:20011412130.020
sensory organ morphogenesisGO:00905962000.020
apoptotic processGO:00069151160.020
positive regulation of cellular amino acid metabolic processGO:004576400.020
rna biosynthetic processGO:00327741810.020
positive regulation of apoptotic signaling pathwayGO:200123510.020
convergent extensionGO:00600261180.020
spermatid developmentGO:000728620.020
negative regulation of protein kinase activityGO:000646940.020
meiotic cell cycle processGO:190304630.020
response to carbohydrateGO:000974330.019
response to monosaccharideGO:003428430.019
autophagyGO:000691440.019
regulation of protein complex assemblyGO:004325430.019
growthGO:00400071740.019
retina development in camera type eyeGO:00600411460.019
regulation of synaptic plasticityGO:004816710.019
myeloid cell differentiationGO:0030099860.019
regulation of anatomical structure morphogenesisGO:00226031300.018
regulation of cytoplasmic transportGO:190364940.018
protein localization to plasma membraneGO:007265910.018
epithelial cell differentiationGO:00308551160.018
Fly
adult behaviorGO:003053420.018
regulation of apoptotic processGO:0042981980.018
regulation of reproductive processGO:200024140.018
negative regulation of cell communicationGO:0010648960.018
positive regulation of nucleoside metabolic processGO:004597910.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
cellular response to organic substanceGO:00713101050.018
syncytium formation by plasma membrane fusionGO:0000768120.018
stem cell divisionGO:001714510.018
negative regulation of signalingGO:0023057960.018
regulation of programmed cell deathGO:00430671010.018
cellular response to endogenous stimulusGO:0071495680.018
generation of neuronsGO:00486993850.018
cytokinesisGO:000091030.018
transcription dna templatedGO:00063511810.018
positive regulation of secretion by cellGO:190353210.018
exocytosisGO:000688710.018
axonogenesisGO:00074091520.018
compound eye developmentGO:004874920.018
cellular component disassemblyGO:002241110.018
regulation of mrna processingGO:005068430.018
anterior posterior pattern specificationGO:00099521520.018
cellular response to nutrient levelsGO:003166920.018
neuron projection developmentGO:00311751800.018
regulation of cellular component organizationGO:0051128860.018
Human Mouse
synaptic growth at neuromuscular junctionGO:005112420.018
ribonucleoside monophosphate catabolic processGO:000915840.018
phosphorus metabolic processGO:00067931090.018
Human Fly
cell matrix adhesionGO:000716040.018
regulation of jak stat cascadeGO:004642530.018
liver developmentGO:0001889960.018
cellular component assemblyGO:00226071700.017
regulation of gene expressionGO:00104682650.017
positive regulation of purine nucleotide catabolic processGO:003312310.017
muscle cell developmentGO:00550011150.017
organonitrogen compound metabolic processGO:1901564740.017
Human
negative regulation of kinase activityGO:003367340.017
determination of left right symmetryGO:00073681790.017
cellular response to molecule of bacterial originGO:007121930.017
positive regulation of cell adhesionGO:004578510.017
oxoacid metabolic processGO:0043436310.017
erk1 and erk2 cascadeGO:007037140.017
negative regulation of response to stimulusGO:00485851040.017
atp catabolic processGO:000620040.017
single organism membrane fusionGO:004480120.017
purine ribonucleoside monophosphate catabolic processGO:000916940.017
response to drugGO:004249330.017
system processGO:00030081850.017
transcription from rna polymerase ii promoterGO:0006366800.017
positive regulation of response to stimulusGO:0048584800.017
Mouse Fly
actin polymerization or depolymerizationGO:000815420.017
regulation of synapse organizationGO:005080730.017
peptidyl serine modificationGO:001820920.017
positive regulation of signalingGO:0023056560.016
Mouse Fly
neuron projection morphogenesisGO:00488121610.016
response to endogenous stimulusGO:0009719830.016
regulation of cell activationGO:005086510.016
developmental growth involved in morphogenesisGO:0060560860.016
regulation of cellular protein catabolic processGO:190336210.016
positive regulation of cytoskeleton organizationGO:005149530.016
intracellular signal transductionGO:0035556850.016
Rat Fly
negative regulation of catabolic processGO:000989530.016
positive regulation of nucleotide catabolic processGO:003081310.016
regulation of cell substrate adhesionGO:001081010.016
positive regulation of secretionGO:005104710.016
heterocycle biosynthetic processGO:00181302150.016
response to alkaloidGO:004327920.016
spermatid differentiationGO:004851520.016
regulation of biosynthetic processGO:00098892500.016
rna localizationGO:000640340.016
positive regulation of gtpase activityGO:004354710.016
adherens junction organizationGO:003433240.016
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
response to nutrientGO:000758430.016
cellular ketone metabolic processGO:0042180110.016
positive regulation of gtp catabolic processGO:003312610.016
regulation of stem cell proliferationGO:007209120.015
regulation of gtpase activityGO:004308720.015
Human
endosomal transportGO:001619720.015
skeletal system developmentGO:00015011810.015
regulation of protein bindingGO:004339330.015
embryonic heart tube developmentGO:00350501330.015
response to other organismGO:0051707970.015
cellular component biogenesisGO:00440851780.015
response to bacteriumGO:0009617580.015
post embryonic organ developmentGO:004856940.015
Fly
protein complex disassemblyGO:004324110.015
skeletal muscle organ developmentGO:0060538780.015
neuron developmentGO:00486662620.015
cellular protein modification processGO:00064641000.015
dorsal ventral pattern formationGO:00099531250.015
positive regulation of protein complex assemblyGO:003133420.015
regulation of protein ubiquitinationGO:003139630.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
negative regulation of intracellular transportGO:003238730.015
regulation of rna metabolic processGO:00512522240.015
stem cell differentiationGO:00488631170.015
specification of symmetryGO:00097992040.015
eye morphogenesisGO:00485921440.015
response to external biotic stimulusGO:0043207970.014
lateral inhibitionGO:004633110.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
wnt signaling pathwayGO:0016055800.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
phosphate containing compound metabolic processGO:00067961080.014
Human Fly
determination of bilateral symmetryGO:00098552040.014
response to biotic stimulusGO:0009607970.014
pigmentationGO:0043473850.014
protein polyubiquitinationGO:000020940.014
neurological system processGO:0050877620.014
cellular response to starvationGO:000926710.014
lipid catabolic processGO:001604240.014
secondary metabolic processGO:001974830.014
membrane fusionGO:006102520.014
purine nucleoside monophosphate catabolic processGO:000912840.014
response to uvGO:000941130.014
regulation of neural precursor cell proliferationGO:200017730.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
positive regulation of map kinase activityGO:004340630.014
nucleoside monophosphate catabolic processGO:000912540.014
regulation of cell developmentGO:00602841000.014
cellular carbohydrate metabolic processGO:004426240.014
protein secretionGO:000930610.013
cellular response to radiationGO:007147840.013
golgi vesicle transportGO:004819330.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
fertilizationGO:000956630.013
cilium morphogenesisGO:0060271850.013
locomotor rhythmGO:004547530.013
developmental programmed cell deathGO:001062340.013
somatic stem cell maintenanceGO:003501910.013
negative regulation of cellular catabolic processGO:003133030.013
negative regulation of protein transportGO:005122430.013
determination of heart left right asymmetryGO:00613711170.013
response to topologically incorrect proteinGO:003596620.013
sequestering of calcium ionGO:005120830.013
negative regulation of protein localization to nucleusGO:190018120.013
urogenital system developmentGO:0001655970.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.013
mesenchymal cell differentiationGO:0048762870.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
macroautophagyGO:001623610.013
segmentationGO:0035282970.013
muscle tissue developmentGO:00605371100.013
centrosome organizationGO:005129710.013
ras protein signal transductionGO:000726570.013
Rat
regulation of erk1 and erk2 cascadeGO:007037240.013
cell projection assemblyGO:0030031640.013
primary neural tube formationGO:001402010.013
epithelial tube morphogenesisGO:00605621480.013
sensory perception of painGO:001923310.013
mesoderm developmentGO:0007498880.013
sequestering of metal ionGO:005123830.013
regulation of epithelial cell proliferationGO:005067830.013
response to glucoseGO:000974930.013
forebrain developmentGO:0030900960.013
cytosolic calcium ion transportGO:006040130.012
cytoskeleton organizationGO:0007010960.012
Human Mouse
protein homooligomerizationGO:005126030.012
embryonic skeletal system developmentGO:0048706970.012
striated muscle cell developmentGO:00550021080.012
organelle fusionGO:004828430.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
cellular protein metabolic processGO:00442671290.012
regulation of localizationGO:00328791040.012
leukocyte homeostasisGO:000177620.012
cartilage developmentGO:0051216960.012
i kappab kinase nf kappab signalingGO:000724940.012
microtubule organizing center organizationGO:003102310.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
convergent extension involved in gastrulationGO:0060027710.012
hepaticobiliary system developmentGO:0061008980.012
positive regulation of signal transductionGO:0009967560.012
Mouse Fly
protein polymerizationGO:005125840.012
positive regulation of immune effector processGO:000269930.012
small gtpase mediated signal transductionGO:000726480.012
Rat
syncytium formationGO:0006949120.012
regulation of dna replicationGO:000627530.012
response to hexoseGO:000974630.012
response to oxygen containing compoundGO:1901700550.012
negative regulation of signal transductionGO:0009968940.012
negative regulation of mapk cascadeGO:004340940.012
stem cell developmentGO:0048864820.012
positive regulation of dna metabolic processGO:005105410.012
phagocytosis engulfmentGO:000691110.012
Fly
negative regulation of macromolecule metabolic processGO:0010605760.012
negative regulation of developmental processGO:0051093650.012
protein acetylationGO:000647320.012
homeostatic processGO:00425921420.012
actin filament polymerizationGO:003004120.011
macromolecular complex disassemblyGO:003298410.011
regulation of reactive oxygen species metabolic processGO:200037720.011
multi organism processGO:00517041340.011
Fly
protein stabilizationGO:005082120.011
camera type eye morphogenesisGO:00485931080.011
embryonic skeletal system morphogenesisGO:0048704930.011
odontogenesis of dentin containing toothGO:004247510.011
negative regulation of immune responseGO:005077720.011
regulation of sequestering of calcium ionGO:005128240.011
kidney developmentGO:0001822920.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
positive regulation of epithelial cell proliferationGO:005067910.011
tissue remodelingGO:004877140.011
female sex differentiationGO:004666040.011
protein dephosphorylationGO:000647030.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
mitotic cell cycleGO:0000278640.011
regulation of metal ion transportGO:001095940.011
translational initiationGO:000641330.011
somatic muscle developmentGO:000752540.011
cellular component assembly involved in morphogenesisGO:00109271070.011
chemosensory behaviorGO:000763510.011
negative regulation of programmed cell deathGO:0043069580.011
negative regulation of cytokine productionGO:000181810.011
regulation of cell cycleGO:0051726520.011
interspecies interaction between organismsGO:004441940.011
erythrocyte homeostasisGO:0034101550.011
negative regulation of cell deathGO:0060548600.011
response to corticosteroidGO:003196010.011
regulation of wnt signaling pathwayGO:0030111530.011
leukocyte proliferationGO:007066110.011
muscle organ developmentGO:00075171010.011
regulation of protein metabolic processGO:0051246560.011
skeletal system morphogenesisGO:00487051020.011
renal system developmentGO:0072001940.011
regulation of stem cell differentiationGO:200073640.011
positive regulation of cell activationGO:005086710.011
erythrocyte differentiationGO:0030218540.011
cellular response to topologically incorrect proteinGO:003596720.010
mitotic dna damage checkpointGO:004477340.010
calcium ion transport into cytosolGO:006040230.010
establishment of protein localization to plasma membraneGO:009000210.010
wound healingGO:0042060900.010
macromolecule modificationGO:00434121110.010
neural crest cell differentiationGO:0014033720.010
negative regulation of translationGO:001714810.010
somite developmentGO:0061053960.010
positive regulation of cytosolic calcium ion concentrationGO:000720440.010
protein modification processGO:00362111000.010
olfactory bulb developmentGO:002177240.010
negative regulation of multi organism processGO:004390130.010
negative regulation of nitrogen compound metabolic processGO:0051172590.010
embryonic heart tube morphogenesisGO:00031431080.010
positive regulation of cell communicationGO:0010647560.010
Mouse Fly
negative regulation of cellular metabolic processGO:0031324770.010
cytoskeleton dependent cytokinesisGO:006164030.010
protein targeting to membraneGO:000661210.010
regulation of transcription from rna polymerase ii promoterGO:00063571140.010
cell fate commitmentGO:0045165990.010
internal protein amino acid acetylationGO:000647520.010
positive regulation of metabolic processGO:00098931080.010
Fly
inner ear developmentGO:00488391260.010

crk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
disease of cellular proliferationDOID:1456600.021
cancerDOID:16200.021
organ system cancerDOID:005068600.021
nervous system diseaseDOID:86300.015
disease of metabolismDOID:001466700.014
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011
musculoskeletal system diseaseDOID:1700.011