Danio rerio

52 known processes

dmd

dystrophin

(Aliases: cb664,zfDYS,zgc:110165,im:6911785,Dp71)

dmd biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle structure developmentGO:00610611960.999
striated muscle tissue developmentGO:00147061100.977
muscle cell developmentGO:00550011150.963
neuron projection guidanceGO:0097485860.930
cell projection organizationGO:00300302840.928
skeletal muscle tissue developmentGO:0007519670.927
myofibril assemblyGO:0030239480.900
actomyosin structure organizationGO:0031032530.897
striated muscle cell developmentGO:00550021080.897
system processGO:00030081850.891
axon guidanceGO:0007411860.887
muscle cell migrationGO:001481240.858
cellular component morphogenesisGO:00329893360.825
muscle organ developmentGO:00075171010.817
cell morphogenesis involved in differentiationGO:00009041950.815
axonogenesisGO:00074091520.802
striated muscle cell differentiationGO:00511461290.791
axon ensheathmentGO:0008366180.785
muscle cell differentiationGO:00426921390.774
generation of neuronsGO:00486993850.770
response to chemicalGO:00422213200.762
skeletal muscle organ developmentGO:0060538780.747
response to external stimulusGO:00096052640.738
growthGO:00400071740.733
skeletal muscle fiber developmentGO:0048741350.717
locomotionGO:00400113130.694
neuron differentiationGO:00301823530.678
muscle tissue developmentGO:00605371100.678
cellular component assembly involved in morphogenesisGO:00109271070.673
neuron projection morphogenesisGO:00488121610.671
cell migrationGO:00164772370.648
motor neuron axon guidanceGO:0008045230.642
embryonic organ developmentGO:00485683810.624
regulation of epithelial cell proliferationGO:005067830.600
cell projection assemblyGO:0030031640.588
embryonic organ morphogenesisGO:00485622740.587
organelle organizationGO:00069962270.586
regulation of developmental processGO:00507932470.584
chemotaxisGO:00069351040.580
transmission of nerve impulseGO:0019226190.575
regulation of biological qualityGO:00650082630.563
neuron developmentGO:00486662620.555
notochord morphogenesisGO:0048570170.551
axon developmentGO:00615641660.523
retinal ganglion cell axon guidanceGO:0031290350.521
cellular component movementGO:00069283350.515
neuron projection developmentGO:00311751800.508
embryo development ending in birth or egg hatchingGO:00097922710.504
neuronal action potentialGO:0019228180.502
commissural neuron axon guidanceGO:007167930.501
smoothened signaling pathwayGO:0007224300.489
nerve developmentGO:0021675450.479
neurological system processGO:0050877620.478
chordate embryonic developmentGO:00430092710.477
larval developmentGO:000216420.469
single organism localizationGO:19025782250.458
glial cell developmentGO:0021782200.455
cellular nitrogen compound metabolic processGO:00346412900.447
synaptic transmissionGO:0007268350.437
heterocycle metabolic processGO:00464832900.426
multicellular organismal signalingGO:0035637220.414
digestive system developmentGO:00551232890.412
taxisGO:00423301090.410
heart processGO:0003015710.398
myelinationGO:0042552180.381
digestive tract developmentGO:00485652650.375
negative regulation of neuron projection developmentGO:001097790.374
actin filament based processGO:0030029640.373
single organism transportGO:00447652060.372
neuroblast proliferationGO:000740520.364
basement membrane assemblyGO:007083130.362
cell morphogenesisGO:00009022890.361
circadian sleep wake cycleGO:004274520.361
establishment of localizationGO:00512342440.356
gene expressionGO:00104672520.353
action potentialGO:0001508190.348
blood circulationGO:0008015870.342
skeletal system developmentGO:00015011810.341
circulatory system processGO:0003013870.340
organelle assemblyGO:00709251100.327
regulation of programmed cell deathGO:00430671010.324
cell morphogenesis involved in neuron differentiationGO:00486671630.324
camera type eye developmentGO:00430102220.318
cell part morphogenesisGO:00329902460.311
detection of mechanical stimulus involved in sensory perceptionGO:0050974110.309
sarcomere organizationGO:0045214260.308
regulation of synapse assemblyGO:005196330.308
cellular localizationGO:0051641970.296
synaptic transmission cholinergicGO:000727140.291
behaviorGO:0007610740.289
transportGO:00068102200.280
organic substance biosynthetic processGO:19015762890.271
myotube cell developmentGO:0014904350.271
purine ribonucleoside monophosphate catabolic processGO:000916940.270
signal transductionGO:00071654550.267
receptor clusteringGO:004311370.261
regulation of blood circulationGO:1903522320.255
regulation of membrane potentialGO:0042391230.250
neuromast developmentGO:0048884460.242
cellular component biogenesisGO:00440851780.240
response to drugGO:004249330.233
embryonic skeletal system developmentGO:0048706970.233
spermatid developmentGO:000728620.227
nitrogen compound metabolic processGO:00068073190.227
programmed cell deathGO:00125011190.221
regulation of synaptic growth at neuromuscular junctionGO:000858210.220
neuromuscular synaptic transmissionGO:000727420.214
protein metabolic processGO:00195381830.212
cellular component assemblyGO:00226071700.206
myotube differentiationGO:0014902450.199
response to stressGO:00069502630.195
head developmentGO:00603223030.188
post embryonic morphogenesisGO:000988640.180
skeletal muscle thin filament assemblyGO:003024040.175
notochord developmentGO:0030903540.175
synaptic growth at neuromuscular junctionGO:005112420.168
cell motilityGO:00488702440.166
nuclear transportGO:005116940.166
membrane repolarizationGO:008600920.164
cell projection morphogenesisGO:00488582440.161
spermatid differentiationGO:004851520.161
regulation of developmental growthGO:0048638380.157
anatomical structure homeostasisGO:0060249360.157
single organism nuclear importGO:190259330.156
interaction with hostGO:005170140.154
organic cyclic compound metabolic processGO:19013603010.152
negative regulation of cellular processGO:00485232830.149
muscle fiber developmentGO:0048747520.147
single organism reproductive processGO:0044702400.146
morphogenesis of an epitheliumGO:00020093330.144
agingGO:000756820.142
heart contractionGO:0060047710.139
actin cytoskeleton organizationGO:0030036630.137
circadian sleep wake cycle sleepGO:005080210.136
response to abiotic stimulusGO:00096281220.135
determination of heart left right asymmetryGO:00613711170.133
regulation of macromolecule metabolic processGO:00602553170.130
androgen metabolic processGO:000820920.130
negative regulation of epithelial cell proliferationGO:005068010.128
negative regulation of biological processGO:00485193040.123
protein importGO:001703830.123
heart morphogenesisGO:00030071560.122
positive regulation of developmental processGO:0051094500.121
regulation of cell developmentGO:00602841000.119
homeostatic processGO:00425921420.119
regulation of cellular metabolic processGO:00313233200.117
deathGO:00162651210.117
regulation of synapse organizationGO:005080730.116
negative regulation of macromolecule biosynthetic processGO:0010558480.114
central nervous system neuron differentiationGO:0021953740.113
regulation of metabolic processGO:00192223590.113
gliogenesisGO:0042063450.109
nucleoside monophosphate catabolic processGO:000912540.108
protein localization to nucleusGO:003450430.106
nucleic acid metabolic processGO:00903042440.105
regulation of cellular biosynthetic processGO:00313262450.104
nucleocytoplasmic transportGO:000691340.104
neurotransmitter transportGO:000683620.103
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.102
detection of abiotic stimulusGO:0009582240.102
establishment of protein localization to organelleGO:007259440.101
cellular response to external stimulusGO:007149620.101
regulation of neural retina developmentGO:006107420.100
regulation of skeletal muscle fiber developmentGO:004874220.100
inositol lipid mediated signalingGO:004801720.099
cell cell signalingGO:0007267520.099
eye developmentGO:00016542770.099
post embryonic developmentGO:000979170.097
tube morphogenesisGO:00352393490.096
regulation of response to stimulusGO:00485832690.095
positive regulation of cellular component biogenesisGO:004408930.094
cellular macromolecule metabolic processGO:00442603910.093
apoptotic processGO:00069151160.093
transmembrane transportGO:00550851200.092
heart developmentGO:00075073130.090
muscle contractionGO:0006936180.090
neuron recognitionGO:0008038180.089
regulation of cellular amino acid metabolic processGO:000652100.086
purine nucleoside monophosphate catabolic processGO:000912840.086
positive regulation of cellular catabolic processGO:003133130.085
atp catabolic processGO:000620040.085
blood vessel morphogenesisGO:00485142160.085
cell migration involved in sprouting angiogenesisGO:000204280.085
detection of stimulusGO:0051606290.085
regulation of axonogenesisGO:0050770320.084
response to organic substanceGO:00100331530.083
regulation of protein ubiquitinationGO:003139630.082
regulation of cell communicationGO:00106462320.082
vasculature developmentGO:00019442780.081
sleepGO:003043110.081
cognitionGO:005089010.080
regulation of skeletal muscle tissue developmentGO:004864140.080
nuclear importGO:005117030.080
rna metabolic processGO:00160702190.079
muscle system processGO:0003012200.078
retina development in camera type eyeGO:00600411460.078
localization of cellGO:00516742440.078
muscle attachmentGO:001620390.078
multicellular organism growthGO:003526440.077
regulation of reproductive processGO:200024140.076
fin developmentGO:0033333770.076
blood vessel developmentGO:00015682460.076
cell matrix adhesionGO:000716040.074
regulation of nucleobase containing compound metabolic processGO:00192192500.074
single organism behaviorGO:0044708240.074
ameboidal type cell migrationGO:00016671430.074
regulation of intracellular protein transportGO:003315730.073
single organism membrane organizationGO:0044802200.073
cytoskeleton organizationGO:0007010960.073
brain morphogenesisGO:0048854180.072
neuron projection regenerationGO:0031102160.072
reactive nitrogen species metabolic processGO:200105700.072
regulation of cell morphogenesisGO:0022604420.070
small molecule metabolic processGO:0044281770.070
cellular nitrogen compound biosynthetic processGO:00442712180.070
appendage developmentGO:0048736800.070
aromatic compound biosynthetic processGO:00194382170.068
stem cell differentiationGO:00488631170.068
embryonic heart tube developmentGO:00350501330.067
organonitrogen compound metabolic processGO:1901564740.066
protein localizationGO:0008104400.066
negative regulation of metabolic processGO:0009892860.065
cellular aromatic compound metabolic processGO:00067252950.065
regulation of myotube differentiationGO:001083020.065
endochondral bone growthGO:000341620.064
establishment of localization in cellGO:0051649770.063
positive regulation of transportGO:005105020.062
positive regulation of macromolecule metabolic processGO:0010604930.062
mesenchymal cell developmentGO:0014031780.062
regulation of cellular macromolecule biosynthetic processGO:20001122220.062
growth plate cartilage developmentGO:000341720.062
axon extensionGO:0048675450.061
hindbrain developmentGO:0030902910.060
neuromast hair cell differentiationGO:0048886120.060
protein targeting to nucleusGO:004474430.060
embryonic viscerocranium morphogenesisGO:0048703520.060
schwann cell developmentGO:001404490.060
regulation of signalingGO:00230512350.059
regulation of smoothened signaling pathwayGO:0008589180.059
cellular response to starvationGO:000926710.059
regulation of cellular component organizationGO:0051128860.059
central nervous system developmentGO:00074173870.058
macromolecule localizationGO:0033036540.058
cellular macromolecule biosynthetic processGO:00346452240.058
embryonic skeletal system morphogenesisGO:0048704930.058
negative regulation of signal transductionGO:0009968940.057
developmental maturationGO:0021700340.056
cellular response to hormone stimulusGO:0032870390.056
ossificationGO:0001503230.055
cellular protein modification processGO:00064641000.054
circadian sleep wake cycle processGO:002241020.054
negative regulation of macromolecule metabolic processGO:0010605760.054
regulation of growthGO:0040008420.054
regulation of cell proliferationGO:0042127370.054
single organism metabolic processGO:00447102170.054
female meiosis chromosome segregationGO:001632110.053
regulation of rna biosynthetic processGO:20011412130.053
cell cycle arrestGO:000705010.053
regulation of nucleoside metabolic processGO:000911820.053
cell deathGO:00082191210.053
extracellular matrix organizationGO:0030198270.052
detection of stimulus involved in sensory perceptionGO:0050906210.050
positive regulation of protein kinase b signalingGO:005189710.050
negative regulation of cell projection organizationGO:003134590.049
histone h3 k9 modificationGO:006164750.049
regionalizationGO:00030022740.048
positive regulation of multicellular organismal processGO:0051240520.048
reproductive processGO:0022414400.048
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.047
regulation of locomotionGO:0040012550.047
growth plate cartilage morphogenesisGO:000342210.047
somitogenesisGO:0001756870.047
pigmentationGO:0043473850.046
voluntary skeletal muscle contractionGO:000301040.046
myelination in peripheral nervous systemGO:002201140.046
regulation of bindingGO:005109830.046
neural crest cell differentiationGO:0014033720.045
regulation of heart contractionGO:0008016320.045
amine metabolic processGO:000930820.045
skeletal system morphogenesisGO:00487051020.045
regulation of protein modification by small protein conjugation or removalGO:190332030.044
developmental process involved in reproductionGO:0003006270.044
cellular protein localizationGO:0034613200.043
regulation of apoptotic processGO:0042981980.043
neuron migrationGO:0001764220.043
positive regulation of catabolic processGO:000989640.043
embryonic cranial skeleton morphogenesisGO:0048701900.042
swim bladder inflationGO:004879850.041
biosynthetic processGO:00090582940.041
medial fin developmentGO:0033338160.040
polarized epithelial cell differentiationGO:003085940.040
regulation of multicellular organismal processGO:00512392770.040
single organism cellular localizationGO:1902580460.040
medial fin morphogenesisGO:0035141140.040
macromolecular complex subunit organizationGO:0043933740.039
positive regulation of smoothened signaling pathwayGO:004588050.039
macromolecule biosynthetic processGO:00090592270.039
ribonucleoside monophosphate catabolic processGO:000915840.039
regulation of macromolecule biosynthetic processGO:00105562250.039
detection of external stimulusGO:0009581240.038
negative regulation of cell communicationGO:0010648960.038
neural tube patterningGO:0021532330.038
swim bladder maturationGO:004879650.038
negative regulation of cellular metabolic processGO:0031324770.037
eye morphogenesisGO:00485921440.037
spermatogenesisGO:000728370.036
mesenchyme developmentGO:00604851270.036
cell proliferationGO:0008283800.036
heterocycle biosynthetic processGO:00181302150.035
positive regulation of cell cycleGO:004578730.035
modulation by virus of host morphology or physiologyGO:001904810.034
positive regulation of cell matrix adhesionGO:000195410.034
protein localization to membraneGO:007265790.034
regulation of biosynthetic processGO:00098892500.034
astrocyte differentiationGO:004870810.033
musculoskeletal movementGO:005088180.033
nucleic acid templated transcriptionGO:00976591810.032
response to estrogenGO:0043627270.032
negative regulation of histone modificationGO:003105710.032
neuromuscular processGO:005090570.032
t tubule organizationGO:003329230.032
positive regulation of skeletal muscle tissue developmentGO:004864310.032
oocyte anterior posterior axis specificationGO:000731440.032
protein import into nucleusGO:000660630.031
gamete generationGO:0007276330.031
extraocular skeletal muscle developmentGO:000207430.031
oogenesisGO:0048477140.031
angiogenesisGO:00015251580.031
regulation of anatomical structure morphogenesisGO:00226031300.031
innervationGO:006038430.031
regenerationGO:0031099910.030
regulation of nervous system developmentGO:0051960900.030
ear morphogenesisGO:0042471640.030
sensory perceptionGO:0007600390.030
response to endogenous stimulusGO:0009719830.030
muscle cell fate determinationGO:000752110.029
lens development in camera type eyeGO:0002088220.029
cellular process involved in reproduction in multicellular organismGO:0022412280.029
somite developmentGO:0061053960.029
sensory neuron axon guidanceGO:009737430.029
brain developmentGO:00074202930.029
response to axon injuryGO:0048678140.029
proteolysis involved in cellular protein catabolic processGO:005160330.028
regulation of nitrogen compound metabolic processGO:00511712510.028
negative regulation of protein kinase b signalingGO:005189820.028
endocardial cell differentiationGO:006095650.027
startle responseGO:000196440.027
regulation of epidermis developmentGO:004568220.027
single organism organelle organizationGO:19025891990.027
regulation of endothelial cell proliferationGO:000193610.027
stem cell proliferationGO:007208940.027
multi organism processGO:00517041340.027
negative regulation of multicellular organismal processGO:0051241690.025
glomerular basement membrane developmentGO:003283650.025
body morphogenesisGO:0010171160.025
axonal fasciculationGO:0007413110.025
regulation of neuron projection developmentGO:0010975400.025
myotome developmentGO:006105510.025
exocrine system developmentGO:0035272280.025
neuromuscular junction developmentGO:000752890.025
regulation of primary metabolic processGO:00800903110.024
lateral line system developmentGO:0048925760.024
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.024
regulation of synapse structure and activityGO:005080350.024
chondrocyte intercalation involved in growth plate cartilage morphogenesisGO:000342810.024
gland developmentGO:00487321430.024
cellular protein metabolic processGO:00442671290.024
negative regulation of cellular protein metabolic processGO:0032269160.024
basement membrane organizationGO:007171150.024
regulation of gene expressionGO:00104682650.024
multi organism reproductive processGO:0044703360.024
regulation of nucleotide catabolic processGO:003081120.024
cellular response to extracellular stimulusGO:003166820.023
locomotory behaviorGO:0007626340.023
regulation of rna metabolic processGO:00512522240.023
stem cell developmentGO:0048864820.023
sensory organ developmentGO:00074233930.023
neural crest cell developmentGO:0014032620.023
regulation of retina development in camera type eyeGO:190286620.023
positive regulation of cellular processGO:00485222010.022
cell cycle g1 s phase transitionGO:004484310.022
glial cell migrationGO:000834730.022
cellular response to stressGO:0033554620.022
regulation of circadian sleep wake cycle sleepGO:004518710.022
maintenance of locationGO:005123540.022
positive regulation of purine nucleotide catabolic processGO:003312310.022
cell maturationGO:0048469230.022
epithelial cell differentiationGO:00308551160.022
regulation of establishment of protein localizationGO:007020140.021
schwann cell differentiationGO:001403790.021
negative regulation of locomotionGO:0040013180.021
germ cell developmentGO:0007281220.021
visual perceptionGO:0007601170.021
secondary metabolic processGO:001974830.021
regulation of dendrite developmentGO:005077330.021
epithelial tube morphogenesisGO:00605621480.021
cellular amine metabolic processGO:004410620.021
lens fiber cell morphogenesisGO:007030930.021
sensory perception of mechanical stimulusGO:0050954160.021
regulation of protein targetingGO:190353320.020
response to mechanical stimulusGO:0009612240.020
developmental growthGO:00485891660.020
response to lipidGO:0033993600.020
cell type specific apoptotic processGO:0097285220.020
neural crest cell migrationGO:0001755420.020
cellular response to endogenous stimulusGO:0071495680.020
negative chemotaxisGO:005091910.020
protein methylationGO:0006479130.020
equilibrioceptionGO:005095720.020
stem cell divisionGO:001714510.019
glial cell differentiationGO:0010001420.019
regulation of signal transductionGO:00099662250.019
cellular amino acid metabolic processGO:000652070.019
neural retina developmentGO:0003407490.019
negative regulation of signalingGO:0023057960.019
sensory system developmentGO:0048880760.019
chromatin organizationGO:0006325220.019
synapse organizationGO:0050808210.019
rna biosynthetic processGO:00327741810.019
g1 s transition of mitotic cell cycleGO:000008210.019
protein modification processGO:00362111000.019
cellular response to chemical stimulusGO:00708871570.019
3 utr mediated mrna stabilizationGO:007093530.019
phosphatidylinositol mediated signalingGO:004801520.019
cellular protein catabolic processGO:004425740.018
adult behaviorGO:003053420.018
neural precursor cell proliferationGO:0061351200.018
regulation of cellular protein catabolic processGO:190336210.018
fin morphogenesisGO:0033334530.018
negative regulation of response to stimulusGO:00485851040.018
translationGO:000641250.018
cellular biosynthetic processGO:00442492860.018
negative regulation of dna metabolic processGO:005105340.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.018
muscle cell cellular homeostasisGO:004671650.017
organic cyclic compound biosynthetic processGO:19013622230.017
regulation of multicellular organism growthGO:004001440.017
negative regulation of developmental processGO:0051093650.017
regulation of neuron differentiationGO:0045664560.017
peripheral nervous system axon ensheathmentGO:003229240.017
carboxylic acid metabolic processGO:0019752220.017
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.017
regulation of cellular amine metabolic processGO:003323800.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
positive regulation of neural precursor cell proliferationGO:200017910.017
convergent extensionGO:00600261180.017
regulation of muscle contractionGO:000693730.017
extracellular structure organizationGO:0043062270.017
mechanosensory lateral line system developmentGO:0048881490.017
regulation of organ growthGO:004662030.016
rna processingGO:0006396250.016
establishment of epithelial cell apical basal polarityGO:004519820.016
lens fiber cell developmentGO:007030730.016
response to hormoneGO:0009725480.016
connective tissue developmentGO:0061448990.016
mitotic cell cycleGO:0000278640.016
cell surface receptor signaling pathwayGO:00071663250.016
cellular macromolecule localizationGO:0070727210.016
embryonic neurocranium morphogenesisGO:0048702150.016
protein kinase b signalingGO:004349190.016
enzyme linked receptor protein signaling pathwayGO:00071671060.016
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.016
negative regulation of mapk cascadeGO:004340940.015
negative regulation of apoptotic processGO:0043066550.015
exocrine pancreas developmentGO:0031017280.015
regulation of cellular component sizeGO:0032535300.015
regulation of purine nucleotide catabolic processGO:003312120.015
organelle localizationGO:0051640490.015
regulation of synaptic transmissionGO:005080440.015
negative regulation of gene expressionGO:0010629650.015
regulation of protein localization to nucleusGO:190018020.015
rna 3 end processingGO:003112320.015
post embryonic organ morphogenesisGO:004856310.014
response to steroid hormoneGO:0048545350.014
modification dependent macromolecule catabolic processGO:004363230.014
ensheathment of neuronsGO:0007272180.014
negative regulation of biosynthetic processGO:0009890550.014
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.014
anterior commissure morphogenesisGO:002196030.014
rna localizationGO:000640340.014
odontogenesis of dentin containing toothGO:004247510.014

dmd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
limb girdle muscular dystrophyDOID:1172400.165
myopathyDOID:42300.165
disease of anatomical entityDOID:700.165
muscle tissue diseaseDOID:6600.165
musculoskeletal system diseaseDOID:1700.165
muscular dystrophyDOID:988400.165
muscular diseaseDOID:008000000.165
congenital muscular dystrophyDOID:005055700.060
kidney diseaseDOID:55700.028
urinary system diseaseDOID:1800.028
central nervous system diseaseDOID:33100.023
nervous system diseaseDOID:86300.023
brain diseaseDOID:93600.023
epilepsy syndromeDOID:182600.020
electroclinical syndromeDOID:005070100.020