Danio rerio

69 known processes

rp2

retinitis pigmentosa 2 (X-linked recessive)

(Aliases: wu:fj10e02,zgc:55632,wu:fm72d05,zfrp2)

rp2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein metabolic processGO:00195381830.417
signal transductionGO:00071654550.375
central nervous system developmentGO:00074173870.297
regulation of signal transductionGO:00099662250.295
zinc ion homeostasisGO:005506910.290
ion transportGO:00068111140.229
regulation of cell communicationGO:00106462320.221
apical protein localizationGO:004517660.214
regulation of biological qualityGO:00650082630.184
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.169
cation transportGO:0006812810.159
tube morphogenesisGO:00352393490.139
regulation of response to stimulusGO:00485832690.138
establishment of localizationGO:00512342440.138
hormone biosynthetic processGO:004244630.137
sensory organ developmentGO:00074233930.133
regulation of signalingGO:00230512350.127
single organism transportGO:00447652060.114
neuron neuron synaptic transmissionGO:000727010.108
morphogenesis of an epitheliumGO:00020093330.107
brain developmentGO:00074202930.106
regulation of metabolic processGO:00192223590.104
deathGO:00162651210.104
locomotionGO:00400113130.102
maintenance of locationGO:005123540.100
cognitionGO:005089010.099
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.093
digestive tract morphogenesisGO:00485462310.089
somite developmentGO:0061053960.087
chordate embryonic developmentGO:00430092710.086
head developmentGO:00603223030.085
lipid storageGO:001991510.084
very long chain fatty acid biosynthetic processGO:004276140.083
cellular response to radiationGO:007147840.081
negative regulation of biological processGO:00485193040.081
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.080
forebrain cell migrationGO:002188510.079
positive regulation of defense response to virus by hostGO:000223000.078
single organism biosynthetic processGO:0044711710.077
positive regulation of transportGO:005105020.076
eye developmentGO:00016542770.073
agingGO:000756820.072
cell surface receptor signaling pathwayGO:00071663250.071
developmental growthGO:00485891660.070
cell deathGO:00082191210.069
specification of symmetryGO:00097992040.069
negative regulation of intrinsic apoptotic signaling pathwayGO:200124380.068
fat soluble vitamin metabolic processGO:000677540.066
cell motilityGO:00488702440.061
regulation of multicellular organism growthGO:004001440.061
cation transmembrane transportGO:0098655650.058
establishment of endothelial barrierGO:006102830.058
response to nutrientGO:000758430.058
regulation of extrinsic apoptotic signaling pathwayGO:200123630.057
regulation of response to oxidative stressGO:190288220.057
heart developmentGO:00075073130.057
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.055
regulation of cellular response to oxidative stressGO:190040720.055
maintenance of cell polarityGO:003001150.055
regulation of intracellular phGO:005145310.055
cellular response to nutrient levelsGO:003166920.054
phosphate containing compound metabolic processGO:00067961080.054
autophagyGO:000691440.051
transportGO:00068102200.051
camera type eye developmentGO:00430102220.049
cell morphogenesisGO:00009022890.049
regulation of defense response to virus by hostGO:005069110.049
cellular response to light stimulusGO:007148240.049
transition metal ion transportGO:000004160.049
establishment or maintenance of epithelial cell apical basal polarityGO:0045197110.048
negative regulation of cellular processGO:00485232830.048
odontogenesis of dentin containing toothGO:004247510.046
small molecule metabolic processGO:0044281770.046
positive regulation of i kappab kinase nf kappab signalingGO:004312330.046
cellular transition metal ion homeostasisGO:004691630.045
heart morphogenesisGO:00030071560.045
mitochondrion organizationGO:000700540.044
embryo development ending in birth or egg hatchingGO:00097922710.044
epiboly involved in gastrulation with mouth forming secondGO:0055113350.043
response to chemicalGO:00422213200.043
multicellular organism growthGO:003526440.042
system processGO:00030081850.042
zinc ion transportGO:000682920.041
wnt signaling pathwayGO:0016055800.041
response to abiotic stimulusGO:00096281220.040
generation of neuronsGO:00486993850.039
cellular response to chemical stimulusGO:00708871570.039
apoptotic processGO:00069151160.038
gastrulationGO:00073692080.037
cellular biosynthetic processGO:00442492860.037
regulation of wnt signaling pathwayGO:0030111530.036
negative regulation of cell communicationGO:0010648960.036
regionalizationGO:00030022740.036
cell agingGO:000756920.035
fatty acid elongationGO:003049710.035
regulation of carbohydrate metabolic processGO:000610940.035
cellular nitrogen compound metabolic processGO:00346412900.035
phosphorus metabolic processGO:00067931090.035
inorganic ion transmembrane transportGO:0098660570.034
cellular hormone metabolic processGO:0034754190.034
regulation of oxidative stress induced cell deathGO:190320120.034
regulation of cellular metabolic processGO:00313233200.034
cellular nitrogen compound biosynthetic processGO:00442712180.034
defense response to other organismGO:0098542330.034
cilium organizationGO:0044782710.033
organelle organizationGO:00069962270.033
stem cell proliferationGO:007208940.033
regulation of circadian rhythmGO:004275240.032
negative regulation of signalingGO:0023057960.032
long chain fatty acid metabolic processGO:000167610.032
cellular response to starvationGO:000926710.032
nucleocytoplasmic transportGO:000691340.031
single organism localizationGO:19025782250.031
protein modification processGO:00362111000.031
signal transduction by p53 class mediatorGO:0072331130.031
carbon dioxide transportGO:001567030.031
regulation of i kappab kinase nf kappab signalingGO:004312240.031
response to zinc ionGO:001004360.030
epithelial tube morphogenesisGO:00605621480.030
transmembrane transportGO:00550851200.030
heterocycle metabolic processGO:00464832900.029
epibolyGO:0090504410.028
androgen metabolic processGO:000820920.028
regulation of calcium ion transportGO:005192420.028
centrosome localizationGO:005164210.028
negative regulation of response to stimulusGO:00485851040.028
long chain fatty acid biosynthetic processGO:004275910.028
regulation of nucleotide catabolic processGO:003081120.028
nitrogen compound metabolic processGO:00068073190.027
negative regulation of apoptotic signaling pathwayGO:2001234100.027
small gtpase mediated signal transductionGO:000726480.027
ion transmembrane transportGO:0034220910.027
neuron differentiationGO:00301823530.027
inorganic cation transmembrane transportGO:0098662500.027
regulation of tube sizeGO:003515020.027
regulation of programmed cell deathGO:00430671010.027
programmed cell deathGO:00125011190.027
hematopoietic or lymphoid organ developmentGO:00485341910.027
establishment of blood brain barrierGO:006085620.027
regulation of metal ion transportGO:001095940.026
organic cyclic compound metabolic processGO:19013603010.026
macromolecule localizationGO:0033036540.026
centrosome cycleGO:000709810.026
cellular response to extracellular stimulusGO:003166820.025
cell part morphogenesisGO:00329902460.025
one carbon compound transportGO:0019755140.025
embryonic organ morphogenesisGO:00485622740.025
positive regulation of developmental processGO:0051094500.025
negative regulation of cell deathGO:0060548600.025
phototransduction visible lightGO:000760320.024
cellular response to molecule of bacterial originGO:007121930.024
larval developmentGO:000216420.024
immune system developmentGO:00025201910.024
regulation of primary metabolic processGO:00800903110.023
cell death in response to oxidative stressGO:003647320.023
regulation of neurotransmitter secretionGO:004692810.023
cellular response to external stimulusGO:007149620.023
embryonic limb morphogenesisGO:003032620.023
cellular protein metabolic processGO:00442671290.023
apical junction assemblyGO:004329710.023
xenobiotic metabolic processGO:000680540.023
cell migrationGO:00164772370.022
regulation of phGO:000688530.022
digestive tract developmentGO:00485652650.022
biosynthetic processGO:00090582940.022
regulation of apoptotic signaling pathwayGO:2001233120.022
growthGO:00400071740.022
positive regulation of response to stimulusGO:0048584800.022
dorsal motor nucleus of vagus nerve developmentGO:002174440.022
positive regulation of cellular processGO:00485222010.022
positive regulation of immune effector processGO:000269930.022
negative regulation of signal transductionGO:0009968940.022
muscle structure developmentGO:00610611960.021
single organism metabolic processGO:00447102170.021
fatty acid elongation unsaturated fatty acidGO:001936810.021
regulation of multicellular organismal processGO:00512392770.021
extrinsic apoptotic signaling pathwayGO:009719130.021
lysosomal transportGO:000704120.021
organic substance biosynthetic processGO:19015762890.021
protein targeting to membraneGO:000661210.020
regulation of neurogenesisGO:0050767870.020
cell substrate adhesionGO:003158940.020
hemopoiesisGO:00300971830.020
cortical cytoskeleton organizationGO:003086510.020
cellular component biogenesisGO:00440851780.020
regulation of nucleoside metabolic processGO:000911820.020
entrainment of circadian clock by photoperiodGO:004315310.020
cellular response to decreased oxygen levelsGO:003629410.020
response to inorganic substanceGO:0010035380.019
renal filtrationGO:0097205100.019
ribosomal small subunit biogenesisGO:004227420.019
cellular carbohydrate metabolic processGO:004426240.019
embryonic organ developmentGO:00485683810.019
immune system processGO:00023762410.019
cilium morphogenesisGO:0060271850.019
synapsisGO:000712910.019
cellular component movementGO:00069283350.018
negative regulation of kinase activityGO:003367340.018
regulation of dna damage response signal transduction by p53 class mediatorGO:004351640.018
hormone metabolic processGO:0042445190.018
detection of light stimulusGO:0009583120.018
regulation of blood vessel sizeGO:005088020.018
epithelial cell morphogenesisGO:000338220.018
modification dependent protein catabolic processGO:001994130.018
morphogenesis of an epithelial sheetGO:0002011490.018
regulation of cellular carbohydrate metabolic processGO:001067540.018
negative regulation of apoptotic processGO:0043066550.018
single organism organelle organizationGO:19025891990.018
photoreceptor cell outer segment organizationGO:003584590.018
rrna catabolic processGO:001607510.017
retrograde axon cargo transportGO:000809010.017
digestive system developmentGO:00551232890.017
heart loopingGO:0001947940.017
cell projection morphogenesisGO:00488582440.017
sodium ion importGO:009736930.017
organonitrogen compound metabolic processGO:1901564740.017
somitogenesisGO:0001756870.017
proteasomal protein catabolic processGO:001049820.017
establishment of endothelial blood brain barrierGO:001404520.017
nucleobase containing compound metabolic processGO:00061392740.017
response to organic substanceGO:00100331530.017
establishment of protein localization to organelleGO:007259440.017
regulation of catalytic activityGO:0050790550.017
monoamine transportGO:001584410.017
purine containing compound biosynthetic processGO:0072522200.017
positive regulation of guanylate cyclase activityGO:003128460.017
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.017
localization of cellGO:00516742440.016
protein kinase b signalingGO:004349190.016
gene expressionGO:00104672520.016
retina development in camera type eyeGO:00600411460.016
neuron developmentGO:00486662620.016
regulation of nitrogen compound metabolic processGO:00511712510.016
negative regulation of developmental processGO:0051093650.016
regulation of cell deathGO:00109411030.016
photoreceptor cell developmentGO:0042461400.016
regulation of apoptotic processGO:0042981980.016
catabolic processGO:0009056320.016
locomotory behaviorGO:0007626340.016
cellular response to stressGO:0033554620.016
embryonic cranial skeleton morphogenesisGO:0048701900.016
regulation of phosphate metabolic processGO:0019220430.016
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.016
nuclear transportGO:005116940.015
photoreceptor cell differentiationGO:0046530550.015
reciprocal dna recombinationGO:003582510.015
neurotransmitter transportGO:000683620.015
ph reductionGO:004585110.015
camera type eye morphogenesisGO:00485931080.015
cellular response to oxygen levelsGO:007145310.015
regulation of response to extracellular stimulusGO:003210410.015
bicarbonate transportGO:001570140.015
regulation of molecular functionGO:0065009700.015
defense response to bacteriumGO:0042742220.015
unidimensional cell growthGO:000982650.015
response to stressGO:00069502630.015
negative regulation of protein phosphorylationGO:000193340.015
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.015
renal system processGO:0003014140.015
pigment granule transportGO:0051904190.014
positive regulation of striated muscle cell differentiationGO:005115510.014
regulation of gtpase activityGO:004308720.014
apoptotic signaling pathwayGO:0097190230.014
telomere organizationGO:003220010.014
cell adhesionGO:0007155400.014
negative regulation of protein kinase activityGO:000646940.014
regulation of sodium ion transportGO:000202820.014
nucleotide biosynthetic processGO:0009165210.014
regulation of dna catabolic processGO:190362410.014
response to alkaloidGO:004327920.014
gastrulation with mouth forming secondGO:0001702440.014
photoreceptor cell morphogenesisGO:000859410.014
rho protein signal transductionGO:000726650.014
macromolecule modificationGO:00434121110.014
ketone biosynthetic processGO:004218120.014
negative regulation of intracellular signal transductionGO:1902532220.014
regulation of neuron migrationGO:200122220.014
response to radiationGO:0009314510.014
nitric oxide mediated signal transductionGO:000726320.014
maintenance of gastrointestinal epitheliumGO:003027770.014
biological adhesionGO:0022610400.013
embryonic skeletal system morphogenesisGO:0048704930.013
cellular component disassemblyGO:002241110.013
fatty acid biosynthetic processGO:000663340.013
vasculature developmentGO:00019442780.013
reciprocal meiotic recombinationGO:000713110.013
antibacterial humoral responseGO:001973120.013
embryonic heart tube morphogenesisGO:00031431080.013
positive regulation of biological processGO:00485182530.013
regulation of anatomical structure morphogenesisGO:00226031300.013
apoptotic process involved in developmentGO:190274220.013
androgen biosynthetic processGO:000670210.013
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233290.013
cellular ketone metabolic processGO:0042180110.013
negative regulation of multicellular organismal processGO:0051241690.013
cellular macromolecule metabolic processGO:00442603910.013
regulation of bone mineralizationGO:003050020.013
dna biosynthetic processGO:007189730.013
positive regulation of catabolic processGO:000989640.013
phosphatidylinositol biosynthetic processGO:000666110.013
meiosis iGO:000712710.013
positive regulation of neuron apoptotic processGO:004352510.013
lipid metabolic processGO:0006629520.013
positive regulation of small gtpase mediated signal transductionGO:005105710.013
regulation of multicellular organismal developmentGO:20000262230.013
visual perceptionGO:0007601170.013
i kappab kinase nf kappab signalingGO:000724940.013
cellular component maintenanceGO:004395430.013
response to external stimulusGO:00096052640.013
protein complex localizationGO:003150310.013
cgmp biosynthetic processGO:000618270.013
regulation of nucleotide biosynthetic processGO:0030808150.012
asymmetric protein localizationGO:000810560.012
positive regulation of multicellular organismal processGO:0051240520.012
regulation of transmembrane transportGO:0034762180.012
response to bacteriumGO:0009617580.012
regulation of production of molecular mediator of immune responseGO:000270010.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
regulation of photoreceptor cell differentiationGO:004653220.012
establishment or maintenance of apical basal cell polarityGO:0035088120.012
heterocycle biosynthetic processGO:00181302150.012
segmentationGO:0035282970.012
b cell activationGO:004211320.012
positive regulation of production of molecular mediator of immune responseGO:000270210.012
lateral inhibitionGO:004633110.012
kidney developmentGO:0001822920.012
nucleic acid metabolic processGO:00903042440.012
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.012
single organismal cell cell adhesionGO:0016337290.012
photoreceptor cell fate commitmentGO:004655210.012
rna transportGO:005065820.012
spermatid differentiationGO:004851520.012
gas transportGO:001566930.012
regulation of cell substrate adhesionGO:001081010.012
intestinal epithelial structure maintenanceGO:006072970.012
regulation of response to biotic stimulusGO:000283120.012
retina morphogenesis in camera type eyeGO:0060042790.012
fat soluble vitamin biosynthetic processGO:004236220.012
cellular response to prostaglandin stimulusGO:007137930.012
cellular response to fatty acidGO:007139830.012
cortical actin cytoskeleton organizationGO:003086610.012
production of molecular mediator of immune responseGO:000244020.012
regulation of dna templated transcription in response to stressGO:004362000.012
renal system developmentGO:0072001940.012
negative regulation of wnt signaling pathwayGO:0030178300.011
cell matrix adhesionGO:000716040.011
epithelial structure maintenanceGO:001066980.011
angiogenesisGO:00015251580.011
regulation of gene expressionGO:00104682650.011
regulation of gtp catabolic processGO:003312420.011
vitamin biosynthetic processGO:000911020.011
adult behaviorGO:003053420.011
notch signaling pathwayGO:0007219350.011
response to vitaminGO:003327330.011
negative regulation of programmed cell deathGO:0043069580.011
muscle tissue developmentGO:00605371100.011
iron ion homeostasisGO:005507240.011
response to glucoseGO:000974930.011
regulation of mitochondrion organizationGO:001082110.011
ras protein signal transductionGO:000726570.011
behaviorGO:0007610740.011
regulation of growthGO:0040008420.011
regulation of response to nutrient levelsGO:003210710.011
gtp catabolic processGO:000618420.011
blood vessel developmentGO:00015682460.011
single organism cell adhesionGO:0098602290.011
bile acid and bile salt transportGO:001572110.011
regulation of macromolecule biosynthetic processGO:00105562250.011
organic substance transportGO:0071702580.011
regulation of cellular protein catabolic processGO:190336210.010
determination of bilateral symmetryGO:00098552040.010
regulation of cell activationGO:005086510.010
negative regulation of epithelial cell proliferationGO:005068010.010
positive regulation of cgmp biosynthetic processGO:003082860.010
regulation of bindingGO:005109830.010
muscle cell differentiationGO:00426921390.010
regulation of microtubule based movementGO:006063230.010
regulation of protein catabolic processGO:004217610.010
single organism nuclear importGO:190259330.010
cellular response to xenobiotic stimulusGO:0071466350.010
cation homeostasisGO:0055080330.010
cell substrate adherens junction assemblyGO:000704510.010
cellular component morphogenesisGO:00329893360.010
cell projection organizationGO:00300302840.010

rp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.058
disease of metabolismDOID:001466700.058
disease of anatomical entityDOID:700.045
nervous system diseaseDOID:86300.027
physical disorderDOID:008001500.021
retinal diseaseDOID:567900.020
eye and adnexa diseaseDOID:149200.020
eye diseaseDOID:561400.020
sensory system diseaseDOID:005015500.020
retinal degenerationDOID:846600.017
integumentary system diseaseDOID:1600.012
anemiaDOID:235500.012
immune system diseaseDOID:291400.012
hematopoietic system diseaseDOID:7400.012