Danio rerio

0 known processes

elk4

ELK4, ETS-domain protein

(Aliases: TCF-1,tcf,MGC114016)

elk4 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of biosynthetic processGO:00098892500.812
nucleic acid metabolic processGO:00903042440.769
nitrogen compound metabolic processGO:00068073190.757
regulation of primary metabolic processGO:00800903110.741
regulation of nucleobase containing compound metabolic processGO:00192192500.710
nucleic acid templated transcriptionGO:00976591810.710
organic cyclic compound metabolic processGO:19013603010.709
cellular biosynthetic processGO:00442492860.663
regulation of rna metabolic processGO:00512522240.618
regulation of nitrogen compound metabolic processGO:00511712510.588
regulation of metabolic processGO:00192223590.582
cellular aromatic compound metabolic processGO:00067252950.565
myeloid cell differentiationGO:0030099860.546
regulation of cellular metabolic processGO:00313233200.539
regulation of macromolecule metabolic processGO:00602553170.534
heterocycle metabolic processGO:00464832900.522
biosynthetic processGO:00090582940.514
immune system processGO:00023762410.503
rna biosynthetic processGO:00327741810.496
developmental growthGO:00485891660.468
cellular macromolecule metabolic processGO:00442603910.459
regulation of cellular biosynthetic processGO:00313262450.449
cellular nitrogen compound metabolic processGO:00346412900.446
regulation of gene expressionGO:00104682650.446
aromatic compound biosynthetic processGO:00194382170.432
regulation of cellular macromolecule biosynthetic processGO:20001122220.414
regulation of macromolecule biosynthetic processGO:00105562250.413
nucleobase containing compound metabolic processGO:00061392740.388
rna metabolic processGO:00160702190.385
cellular macromolecule biosynthetic processGO:00346452240.380
regulation of nucleic acid templated transcriptionGO:19035062130.373
organic cyclic compound biosynthetic processGO:19013622230.366
striated muscle cell differentiationGO:00511461290.365
positive regulation of biological processGO:00485182530.365
immune system developmentGO:00025201910.352
negative regulation of biological processGO:00485193040.349
multicellular organismal reproductive processGO:0048609350.348
negative regulation of cellular processGO:00485232830.342
macromolecule biosynthetic processGO:00090592270.341
gene expressionGO:00104672520.335
cell surface receptor signaling pathwayGO:00071663250.334
gastrulationGO:00073692080.330
regulation of rna biosynthetic processGO:20011412130.319
vasculature developmentGO:00019442780.302
leukocyte differentiationGO:0002521250.298
renal system developmentGO:0072001940.290
regulation of transcription dna templatedGO:00063552130.279
embryonic organ developmentGO:00485683810.273
cellular nitrogen compound biosynthetic processGO:00442712180.271
blood vessel developmentGO:00015682460.268
digestive system developmentGO:00551232890.257
homeostatic processGO:00425921420.254
regulation of multicellular organismal developmentGO:20000262230.250
phagocytosisGO:000690930.238
kidney developmentGO:0001822920.237
hemopoiesisGO:00300971830.236
embryonic organ morphogenesisGO:00485622740.234
blood vessel morphogenesisGO:00485142160.234
digestive tract developmentGO:00485652650.234
somite developmentGO:0061053960.233
nucleobase containing compound biosynthetic processGO:00346542050.233
positive regulation of cellular biosynthetic processGO:0031328680.226
cell part morphogenesisGO:00329902460.224
negative regulation of developmental processGO:0051093650.217
hematopoietic or lymphoid organ developmentGO:00485341910.214
negative regulation of macromolecule metabolic processGO:0010605760.213
organic substance biosynthetic processGO:19015762890.212
positive regulation of metabolic processGO:00098931080.210
mesodermal cell differentiationGO:0048333210.210
diencephalon developmentGO:0021536580.205
apoptotic processGO:00069151160.191
positive regulation of nitrogen compound metabolic processGO:0051173690.190
immune responseGO:0006955280.186
nuclear transportGO:005116940.186
cellular component movementGO:00069283350.185
response to stressGO:00069502630.185
muscle structure developmentGO:00610611960.184
regulation of developmental processGO:00507932470.181
embryonic cranial skeleton morphogenesisGO:0048701900.176
defense responseGO:0006952470.170
heterocycle biosynthetic processGO:00181302150.170
single organism transportGO:00447652060.170
inner ear developmentGO:00488391260.170
transportGO:00068102200.167
mitotic cell cycleGO:0000278640.162
positive regulation of nucleic acid templated transcriptionGO:1903508570.161
phosphorus metabolic processGO:00067931090.161
specification of symmetryGO:00097992040.160
skeletal system developmentGO:00015011810.159
single organism localizationGO:19025782250.159
central nervous system developmentGO:00074173870.159
negative regulation of gene expressionGO:0010629650.158
phosphate containing compound metabolic processGO:00067961080.157
positive regulation of rna biosynthetic processGO:1902680570.155
positive regulation of nucleobase containing compound metabolic processGO:0045935690.155
connective tissue developmentGO:0061448990.151
establishment of localizationGO:00512342440.151
cardiac cell fate commitmentGO:006091110.149
stem cell differentiationGO:00488631170.149
ear developmentGO:00435831270.149
digestive tract morphogenesisGO:00485462310.144
somitogenesisGO:0001756870.143
forebrain developmentGO:0030900960.140
response to chemicalGO:00422213200.140
signal transductionGO:00071654550.139
convergent extensionGO:00600261180.136
embryonic skeletal system developmentGO:0048706970.134
regenerationGO:0031099910.133
single organism metabolic processGO:00447102170.133
negative regulation of multicellular organismal processGO:0051241690.132
mesoderm formationGO:0001707430.131
myeloid cell developmentGO:0061515320.131
regulation of cell deathGO:00109411030.127
pronephros developmentGO:0048793690.125
embryonic heart tube developmentGO:00350501330.125
cell deathGO:00082191210.123
stem cell proliferationGO:007208940.121
positive regulation of biosynthetic processGO:0009891680.117
heart developmentGO:00075073130.115
negative regulation of cell deathGO:0060548600.114
regulation of response to stimulusGO:00485832690.107
chordate embryonic developmentGO:00430092710.107
ameboidal type cell migrationGO:00016671430.104
regulation of establishment of protein localizationGO:007020140.104
cellular response to organic substanceGO:00713101050.101
regulation of cell differentiationGO:00455951420.101
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.101
peptidyl serine phosphorylationGO:001810510.100
pharyngeal muscle developmentGO:004328240.100
regulation of cell proliferationGO:0042127370.100
agingGO:000756820.099
programmed cell deathGO:00125011190.099
cellular carbohydrate metabolic processGO:004426240.098
nucleocytoplasmic transportGO:000691340.098
negative regulation of cell differentiationGO:0045596460.098
response to organic substanceGO:00100331530.097
organelle localizationGO:0051640490.097
regulation of nervous system developmentGO:0051960900.096
locomotionGO:00400113130.096
single organism organelle organizationGO:19025891990.094
cellular amino acid metabolic processGO:000652070.093
deathGO:00162651210.093
single organism reproductive processGO:0044702400.092
positive regulation of stem cell proliferationGO:200064810.092
generation of neuronsGO:00486993850.090
sensory organ morphogenesisGO:00905962000.090
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.090
positive regulation of epithelial cell differentiationGO:003085820.089
head developmentGO:00603223030.088
cellular response to external stimulusGO:007149620.088
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.088
transcription dna templatedGO:00063511810.087
muscle cell differentiationGO:00426921390.086
nephron tubule morphogenesisGO:007207810.086
positive regulation of cellular metabolic processGO:0031325940.085
cell migrationGO:00164772370.085
embryo development ending in birth or egg hatchingGO:00097922710.083
regulation of cytokine productionGO:000181730.083
intracellular signal transductionGO:0035556850.083
morphogenesis of an epitheliumGO:00020093330.082
macromolecule localizationGO:0033036540.082
forebrain regionalizationGO:002187140.080
microtubule based processGO:0007017600.079
regulation of neurogenesisGO:0050767870.078
negative regulation of cellular biosynthetic processGO:0031327550.078
neuron differentiationGO:00301823530.078
phosphorylationGO:0016310690.076
negative regulation of cellular metabolic processGO:0031324770.076
negative regulation of protein phosphorylationGO:000193340.076
regulation of multicellular organism growthGO:004001440.075
segmentationGO:0035282970.074
renal tubule morphogenesisGO:006133310.074
localization of cellGO:00516742440.074
protein modification processGO:00362111000.074
transcription from rna polymerase ii promoterGO:0006366800.073
positive regulation of cellular processGO:00485222010.073
regulation of stem cell proliferationGO:007209120.073
inner ear receptor cell differentiationGO:0060113290.073
cell morphogenesisGO:00009022890.072
gastrulation with mouth forming secondGO:0001702440.071
cellular response to chemical stimulusGO:00708871570.071
stem cell maintenanceGO:001982740.071
positive regulation of macromolecule metabolic processGO:0010604930.070
lymphocyte differentiationGO:003009890.070
female gonad developmentGO:000858540.070
autophagyGO:000691440.069
positive regulation of gene expressionGO:0010628710.069
developmental growth involved in morphogenesisGO:0060560860.069
nephron epithelium morphogenesisGO:007208810.067
determination of left right symmetryGO:00073681790.067
enzyme linked receptor protein signaling pathwayGO:00071671060.067
cell cycle g2 m phase transitionGO:004483940.066
regulation of cell developmentGO:00602841000.066
regulation of heart morphogenesisGO:2000826170.065
response to bacteriumGO:0009617580.065
female sex differentiationGO:004666040.065
protein localization to nucleusGO:003450430.064
negative regulation of cytokine productionGO:000181810.064
regulation of transcription from rna polymerase ii promoterGO:00063571140.064
positive regulation of catabolic processGO:000989640.064
cognitionGO:005089010.064
embryonic skeletal system morphogenesisGO:0048704930.064
mesenchyme developmentGO:00604851270.064
ectodermal placode formationGO:0060788260.064
angiogenesisGO:00015251580.064
axonogenesisGO:00074091520.063
cellular component morphogenesisGO:00329893360.062
multicellular organism reproductionGO:0032504350.062
cellular protein modification processGO:00064641000.062
g2 m transition of mitotic cell cycleGO:000008640.062
heart loopingGO:0001947940.062
i kappab kinase nf kappab signalingGO:000724940.062
regulation of signal transductionGO:00099662250.061
regulation of nucleocytoplasmic transportGO:004682220.061
positive regulation of response to stimulusGO:0048584800.060
nephron morphogenesisGO:007202820.060
negative regulation of cell communicationGO:0010648960.060
chromosome organizationGO:0051276310.059
mesenchymal cell differentiationGO:0048762870.059
mechanoreceptor differentiationGO:0042490370.059
response to endogenous stimulusGO:0009719830.059
foregut morphogenesisGO:000744040.058
thrombocyte differentiationGO:000257440.058
protein phosphorylationGO:0006468470.058
regulation of cellular protein metabolic processGO:0032268520.058
neuron projection extensionGO:1990138450.058
carboxylic acid metabolic processGO:0019752220.058
negative regulation of metabolic processGO:0009892860.057
chromatin modificationGO:0016568210.057
cell motilityGO:00488702440.057
ovulation cycleGO:004269820.057
meiotic nuclear divisionGO:000712640.057
outflow tract morphogenesisGO:000315110.057
mesoderm developmentGO:0007498880.057
determination of bilateral symmetryGO:00098552040.057
neuroblast proliferationGO:000740520.057
erythrocyte homeostasisGO:0034101550.056
development of primary female sexual characteristicsGO:004654540.056
regulation of cell cycleGO:0051726520.056
artery developmentGO:0060840220.055
organ formationGO:0048645170.054
aorta developmentGO:003590440.054
cellular protein metabolic processGO:00442671290.054
regulation of cellular response to growth factor stimulusGO:0090287350.053
determination of heart left right asymmetryGO:00613711170.053
urogenital system developmentGO:0001655970.053
positive regulation of transcription dna templatedGO:0045893570.053
embryonic digestive tract developmentGO:004856640.053
stem cell developmentGO:0048864820.052
regulation of inner ear receptor cell differentiationGO:200098010.052
regulation of apoptotic processGO:0042981980.052
response to oxygen levelsGO:0070482250.052
sensory organ developmentGO:00074233930.051
phagocytosis engulfmentGO:000691110.051
multicellular organism growthGO:003526440.051
epithelial cell differentiationGO:00308551160.050
brain developmentGO:00074202930.050
cellular ketone metabolic processGO:0042180110.050
protein metabolic processGO:00195381830.050
peripheral nervous system neuron differentiationGO:0048934280.049
regulation of biological qualityGO:00650082630.049
positive regulation of rna metabolic processGO:0051254590.049
cellular localizationGO:0051641970.049
single organism cellular localizationGO:1902580460.049
regulation of growthGO:0040008420.048
positive regulation of macromolecule biosynthetic processGO:0010557590.048
cell proliferationGO:0008283800.047
organelle organizationGO:00069962270.047
tube morphogenesisGO:00352393490.047
ovulation cycle processGO:002260220.047
formation of primary germ layerGO:0001704620.047
sensory system developmentGO:0048880760.047
positive regulation of cellular component biogenesisGO:004408930.047
negative regulation of apoptotic processGO:0043066550.046
homeostasis of number of cellsGO:0048872620.046
erythrocyte differentiationGO:0030218540.046
embryonic digestive tract morphogenesisGO:004855730.046
positive regulation of cell adhesionGO:004578510.046
rhombomere developmentGO:0021546190.046
cellular component assemblyGO:00226071700.046
primitive hemopoiesisGO:0060215270.045
positive regulation of cell cycleGO:004578730.045
endocytosisGO:0006897160.045
regulation of programmed cell deathGO:00430671010.045
larval developmentGO:000216420.044
regulation of epithelial cell proliferationGO:005067830.044
regulation of protein bindingGO:004339330.044
cell cycleGO:0007049930.044
peptidyl serine modificationGO:001820920.044
mediolateral intercalationGO:006003130.044
chromatin organizationGO:0006325220.044
positive regulation of transportGO:005105020.043
skeletal muscle organ developmentGO:0060538780.043
sprouting angiogenesisGO:0002040530.043
growthGO:00400071740.043
positive regulation of muscle organ developmentGO:004863610.043
regulation of signalingGO:00230512350.043
response to decreased oxygen levelsGO:0036293250.042
ear morphogenesisGO:0042471640.042
positive regulation of signalingGO:0023056560.042
cartilage developmentGO:0051216960.041
mitotic cell cycle processGO:1903047480.041
regulation of mitotic cell cycleGO:0007346250.041
cell fate commitmentGO:0045165990.041
protein targeting to nucleusGO:004474430.041
regulation of immune system processGO:0002682340.041
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.040
regulation of autophagyGO:001050630.040
negative regulation of nervous system developmentGO:0051961220.040
protein heterooligomerizationGO:005129110.040
regulation of intracellular protein transportGO:003315730.040
negative regulation of map kinase activityGO:004340720.040
muscle cell developmentGO:00550011150.040
reproductionGO:0000003400.039
negative regulation of kinase activityGO:003367340.039
regulation of inflammatory responseGO:005072720.039
organonitrogen compound metabolic processGO:1901564740.039
negative regulation of nitrogen compound metabolic processGO:0051172590.039
cell substrate adhesionGO:003158940.039
multi organism processGO:00517041340.039
positive regulation of neuron deathGO:190121610.038
canonical wnt signaling pathwayGO:0060070480.038
response to carbohydrateGO:000974330.038
heart morphogenesisGO:00030071560.038
cell cycle processGO:0022402530.038
inner ear morphogenesisGO:0042472630.038
regulation of bindingGO:005109830.038
kidney epithelium developmentGO:0072073230.037
maintenance of locationGO:005123540.037
regulation of neuron differentiationGO:0045664560.037
histone modificationGO:0016570200.037
covalent chromatin modificationGO:0016569200.037
proteolysis involved in cellular protein catabolic processGO:005160330.037
cellular amine metabolic processGO:004410620.037
somatic stem cell maintenanceGO:003501910.037
negative regulation of response to stimulusGO:00485851040.037
response to growth factorGO:0070848390.036
positive regulation of embryonic developmentGO:004001930.036
regulation of cellular component organizationGO:0051128860.036
regulation of protein metabolic processGO:0051246560.036
developmental cell growthGO:0048588520.036
intracellular transportGO:0046907320.036
protein import into nucleusGO:000660630.035
lymphocyte activationGO:0046649100.035
central nervous system neuron differentiationGO:0021953740.035
regulation of multicellular organismal processGO:00512392770.035
positive regulation of multicellular organismal processGO:0051240520.035
negative regulation of programmed cell deathGO:0043069580.035
regulation of bmp signaling pathway involved in heart joggingGO:2000223120.035
erythrocyte developmentGO:0048821240.035
regulation of mesoderm developmentGO:2000380110.035
defense response to other organismGO:0098542330.035
cell migration involved in gastrulationGO:0042074790.035
positive regulation of apoptotic signaling pathwayGO:200123510.035
leukocyte activationGO:0045321120.035
regulation of phosphate metabolic processGO:0019220430.034
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathwayGO:002200210.034
ectodermal placode morphogenesisGO:0071697320.034
response to glucoseGO:000974930.034
regulation of dna templated transcription in response to stressGO:004362000.034
regulation of cell communicationGO:00106462320.034
regulation of protein transportGO:005122330.034
organic substance transportGO:0071702580.034
response to external stimulusGO:00096052640.034
embryonic viscerocranium morphogenesisGO:0048703520.034
hormone transportGO:000991420.033
cytoskeleton organizationGO:0007010960.033
pericardium developmentGO:006003910.033
regulation of synaptic plasticityGO:004816710.033
muscle fiber developmentGO:0048747520.033
regulation of molecular functionGO:0065009700.033
regulation of cell sizeGO:0008361290.033
positive regulation of signal transductionGO:0009967560.033
regulation of stem cell differentiationGO:200073640.033
developmental process involved in reproductionGO:0003006270.033
pharyngeal system developmentGO:0060037180.032
negative regulation of protein kinase activityGO:000646940.032
cellular response to growth factor stimulusGO:0071363390.032
otic vesicle morphogenesisGO:0071600340.032
negative regulation of nucleic acid templated transcriptionGO:1903507450.032
cardioblast migrationGO:000326070.032
regulation of catalytic activityGO:0050790550.031
innate immune responseGO:0045087130.031
embryonic heart tube morphogenesisGO:00031431080.031
small molecule metabolic processGO:0044281770.031
regulation of sequence specific dna binding transcription factor activityGO:005109090.031
defense response to bacteriumGO:0042742220.030
hepaticobiliary system developmentGO:0061008980.030
regulation of cellular amino acid metabolic processGO:000652100.030
tissue regenerationGO:0042246740.030
myeloid cell homeostasisGO:0002262560.030
specification of organ identityGO:001009220.029
hair cell differentiationGO:0035315320.029
negative regulation of macromolecule biosynthetic processGO:0010558480.029
negative regulation of biosynthetic processGO:0009890550.029
regulation of cytoplasmic transportGO:190364940.029
positive regulation of molecular functionGO:0044093330.029
positive regulation of developmental processGO:0051094500.029
glucose homeostasisGO:004259310.029
convergent extension involved in organogenesisGO:0060029100.029
regulation of protein complex assemblyGO:004325430.029
positive regulation of erk1 and erk2 cascadeGO:007037420.029
positive regulation of cell communicationGO:0010647560.028
positive regulation of canonical wnt signaling pathwayGO:009026340.028
response to lipidGO:0033993600.028
organelle assemblyGO:00709251100.028
g1 s transition of mitotic cell cycleGO:000008210.028
spermatid differentiationGO:004851520.028
axon extensionGO:0048675450.028
gall bladder developmentGO:006101010.028
lateral line system developmentGO:0048925760.028
dna metabolic processGO:0006259270.028
dorsal ventral pattern formationGO:00099531250.028
regulation of response to cytokine stimulusGO:006075930.028
negative regulation of signal transductionGO:0009968940.027
regulation of reproductive processGO:200024140.027
membrane invaginationGO:001032410.027
epithelium regenerationGO:1990399140.027
oxoacid metabolic processGO:0043436310.027
cell morphogenesis involved in differentiationGO:00009041950.027
spinal cord anterior posterior patterningGO:002151210.027
striated muscle cell developmentGO:00550021080.027
tissue remodelingGO:004877140.027
regulation of histone methylationGO:003106030.027
extrinsic apoptotic signaling pathwayGO:009719130.027
anterior posterior pattern specificationGO:00099521520.027
definitive hemopoiesisGO:0060216180.027
skeletal muscle tissue developmentGO:0007519670.027
protein stabilizationGO:005082120.026
negative regulation of signalingGO:0023057960.026
hindbrain developmentGO:0030902910.026
peripheral nervous system developmentGO:0007422550.026
response to temperature stimulusGO:0009266150.026
regulation of cellular amine metabolic processGO:003323800.026
otic vesicle formationGO:0030916270.026
adenohypophysis developmentGO:0021984150.026
epithelial to mesenchymal transitionGO:0001837210.026
negative regulation of rna biosynthetic processGO:1902679450.026
response to monosaccharideGO:003428430.026
compound eye developmentGO:004874920.026
regulation of cell shapeGO:000836010.026
cellular response to molecule of bacterial originGO:007121930.026
endocrine system developmentGO:0035270650.026
cellular response to nutrient levelsGO:003166920.026
b cell differentiationGO:003018310.026
mesodermal cell fate commitmentGO:0001710140.025
cell cycle g1 s phase transitionGO:004484310.025
negative regulation of immune responseGO:005077720.025
regulation of immune responseGO:0050776140.025
ubiquitin dependent protein catabolic processGO:000651130.025
locomotor rhythmGO:004547530.025
cellular response to extracellular stimulusGO:003166820.025
positive regulation of cytoskeleton organizationGO:005149530.025
internal protein amino acid acetylationGO:000647520.025
hormone secretionGO:004687920.025
glandular epithelial cell differentiationGO:000206790.025
hard palate developmentGO:006002240.025
macromolecule modificationGO:00434121110.024
regulation of cellular ketone metabolic processGO:001056570.024
regulation of organ growthGO:004662030.024
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.024
posttranscriptional regulation of gene expressionGO:0010608140.024
spermatid developmentGO:000728620.024
positive regulation of muscle tissue developmentGO:190186310.024
embryonic limb morphogenesisGO:003032620.024
regulation of response to stressGO:0080134360.024
regulation of protein modification by small protein conjugation or removalGO:190332030.024
myeloid leukocyte differentiationGO:0002573150.023
response to abiotic stimulusGO:00096281220.023
negative regulation of cellular protein metabolic processGO:0032269160.023
modification dependent macromolecule catabolic processGO:004363230.023
carbohydrate homeostasisGO:003350010.023
response to hexoseGO:000974630.023
camera type eye developmentGO:00430102220.023
cellular response to endogenous stimulusGO:0071495680.023
regulation of erk1 and erk2 cascadeGO:007037240.023
pancreas developmentGO:0031016840.023
regulation of localizationGO:00328791040.023
lateral line developmentGO:0048882660.023
otic vesicle developmentGO:0071599420.023
positive regulation of striated muscle tissue developmentGO:004584410.023
epidermal cell differentiationGO:0009913360.023
secondary metabolic processGO:001974830.023
cellular response to dna damage stimulusGO:0006974240.022
erk1 and erk2 cascadeGO:007037140.022
regulation of organ morphogenesisGO:2000027350.022
regulation of protein targetingGO:190353320.022

elk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.090
disease of cellular proliferationDOID:1456600.044
musculoskeletal system diseaseDOID:1700.041
organ system cancerDOID:005068600.027
cancerDOID:16200.027
bone diseaseDOID:008000100.023
bone development diseaseDOID:008000600.023
connective tissue diseaseDOID:6500.023