Danio rerio

62 known processes

pdgfb

platelet derived growth factor, B polypeptide

(Aliases: si:dkey-261d11.1,si:ch211-79m20.1)

pdgfb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vasculature developmentGO:00019442780.164
regulation of cellular metabolic processGO:00313233200.127
signal transductionGO:00071654550.095
organic substance biosynthetic processGO:19015762890.088
cell surface receptor signaling pathwayGO:00071663250.085
blood vessel morphogenesisGO:00485142160.080
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.079
sprouting angiogenesisGO:0002040530.079
cellular nitrogen compound biosynthetic processGO:00442712180.078
regulation of biosynthetic processGO:00098892500.074
response to stressGO:00069502630.073
heterocycle metabolic processGO:00464832900.069
sensory organ developmentGO:00074233930.069
heart morphogenesisGO:00030071560.068
modification dependent protein catabolic processGO:001994130.067
cellular component movementGO:00069283350.067
ubiquitin dependent protein catabolic processGO:000651130.062
blood vessel developmentGO:00015682460.062
positive regulation of map kinase activityGO:004340630.062
nucleobase containing compound biosynthetic processGO:00346542050.060
eye developmentGO:00016542770.058
nucleic acid metabolic processGO:00903042440.056
response to external stimulusGO:00096052640.056
morphogenesis of an epitheliumGO:00020093330.056
organic cyclic compound metabolic processGO:19013603010.056
proteasomal protein catabolic processGO:001049820.053
small molecule metabolic processGO:0044281770.051
biosynthetic processGO:00090582940.048
heterocycle biosynthetic processGO:00181302150.048
angiogenesisGO:00015251580.046
single organism metabolic processGO:00447102170.046
nitrogen compound metabolic processGO:00068073190.046
rna biosynthetic processGO:00327741810.045
positive regulation of metabolic processGO:00098931080.045
cell motilityGO:00488702440.045
regulation of gene expressionGO:00104682650.044
proteolysis involved in cellular protein catabolic processGO:005160330.043
regulation of macromolecule metabolic processGO:00602553170.043
blood circulationGO:0008015870.043
tube morphogenesisGO:00352393490.043
locomotionGO:00400113130.042
amine metabolic processGO:000930820.041
camera type eye developmentGO:00430102220.040
organic cyclic compound biosynthetic processGO:19013622230.040
positive regulation of transportGO:005105020.040
localization of cellGO:00516742440.040
nucleic acid templated transcriptionGO:00976591810.040
positive regulation of erk1 and erk2 cascadeGO:007037420.039
phagocytosisGO:000690930.038
regulation of cellular biosynthetic processGO:00313262450.038
embryonic organ developmentGO:00485683810.038
hemopoiesisGO:00300971830.037
cellular protein catabolic processGO:004425740.037
regulation of protein complex assemblyGO:004325430.037
response to chemicalGO:00422213200.037
regulation of reactive oxygen species metabolic processGO:200037720.037
stem cell maintenanceGO:001982740.036
regulation of rna biosynthetic processGO:20011412130.035
regulation of neural precursor cell proliferationGO:200017730.034
regulation of transcription dna templatedGO:00063552130.034
positive regulation of phospholipase c activityGO:001086310.034
cell substrate adhesionGO:003158940.033
agingGO:000756820.033
cell migrationGO:00164772370.033
brain developmentGO:00074202930.033
stem cell proliferationGO:007208940.033
rna metabolic processGO:00160702190.032
regulation of primary metabolic processGO:00800903110.032
hematopoietic or lymphoid organ developmentGO:00485341910.032
positive regulation of inflammatory responseGO:005072910.032
response to drugGO:004249330.032
cellular amino acid metabolic processGO:000652070.031
cellular protein metabolic processGO:00442671290.031
cell morphogenesis involved in differentiationGO:00009041950.031
regulation of blood vessel sizeGO:005088020.031
response to decreased oxygen levelsGO:0036293250.030
regulation of metabolic processGO:00192223590.030
cellular response to chemical stimulusGO:00708871570.029
regulation of nucleic acid templated transcriptionGO:19035062130.029
cellular component morphogenesisGO:00329893360.029
digestive system developmentGO:00551232890.029
cellular aromatic compound metabolic processGO:00067252950.029
positive regulation of protein kinase b signalingGO:005189710.029
positive regulation of cellular catabolic processGO:003133130.028
regulation of nitrogen compound metabolic processGO:00511712510.028
head developmentGO:00603223030.027
regulation of cytokine productionGO:000181730.027
heart developmentGO:00075073130.027
regulation of nucleobase containing compound metabolic processGO:00192192500.027
epithelium migrationGO:0090132250.027
regulation of heart contractionGO:0008016320.027
nucleobase containing compound metabolic processGO:00061392740.026
organic acid metabolic processGO:0006082310.026
positive regulation of cell cycleGO:004578730.026
positive regulation of cell matrix adhesionGO:000195410.026
larval developmentGO:000216420.025
embryonic organ morphogenesisGO:00485622740.025
regulation of tube sizeGO:003515020.025
protein localization to nucleusGO:003450430.025
central nervous system developmentGO:00074173870.025
regulation of autophagyGO:001050630.024
positive regulation of signal transductionGO:0009967560.024
regulation of bindingGO:005109830.024
positive regulation of cell adhesionGO:004578510.024
regulation of epithelial cell proliferationGO:005067830.024
positive regulation of catabolic processGO:000989640.024
regulation of cell deathGO:00109411030.024
regulation of cellular amino acid metabolic processGO:000652100.024
transcription dna templatedGO:00063511810.023
oxoacid metabolic processGO:0043436310.023
regulation of inflammatory responseGO:005072720.023
regionalizationGO:00030022740.023
regulation of cellular amine metabolic processGO:003323800.023
positive regulation of biological processGO:00485182530.023
cognitionGO:005089010.023
regulation of rna metabolic processGO:00512522240.023
epithelial tube morphogenesisGO:00605621480.023
circulatory system processGO:0003013870.023
cellular macromolecule metabolic processGO:00442603910.022
positive regulation of nucleic acid templated transcriptionGO:1903508570.022
immune system processGO:00023762410.022
ameboidal type cell migrationGO:00016671430.022
reactive nitrogen species metabolic processGO:200105700.022
intracellular signal transductionGO:0035556850.022
mitochondrion organizationGO:000700540.022
cell morphogenesisGO:00009022890.022
taxisGO:00423301090.022
system processGO:00030081850.022
cellular amine metabolic processGO:004410620.022
maintenance of locationGO:005123540.021
cellular macromolecule biosynthetic processGO:00346452240.021
establishment of protein localization to organelleGO:007259440.021
cellular ketone metabolic processGO:0042180110.021
neuron projection morphogenesisGO:00488121610.021
carboxylic acid metabolic processGO:0019752220.021
response to external biotic stimulusGO:0043207970.021
regulation of cell substrate adhesionGO:001081010.021
meiotic nuclear divisionGO:000712640.021
regulation of hematopoietic progenitor cell differentiationGO:190153210.020
regulation of erk1 and erk2 cascadeGO:007037240.020
extrinsic apoptotic signaling pathwayGO:009719130.020
cell projection morphogenesisGO:00488582440.020
regulation of signalingGO:00230512350.020
neuroblast proliferationGO:000740520.020
cellular response to external stimulusGO:007149620.020
regulation of multicellular organismal developmentGO:20000262230.020
gland developmentGO:00487321430.020
cellular lipid metabolic processGO:0044255360.020
embryonic heart tube developmentGO:00350501330.019
regulation of cytoplasmic transportGO:190364940.019
regulation of cell shapeGO:000836010.019
heart contractionGO:0060047710.019
response to biotic stimulusGO:0009607970.019
regulation of stem cell proliferationGO:007209120.019
phosphate containing compound metabolic processGO:00067961080.019
cell projection organizationGO:00300302840.019
cellular biosynthetic processGO:00442492860.019
modification dependent macromolecule catabolic processGO:004363230.019
ovulation cycleGO:004269820.018
regulation of protein catabolic processGO:004217610.018
cell fate specificationGO:0001708680.018
regulation of developmental processGO:00507932470.018
skeletal system morphogenesisGO:00487051020.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
positive regulation of cytokine productionGO:000181920.018
negative regulation of biosynthetic processGO:0009890550.018
lymphangiogenesisGO:0001946250.018
stem cell differentiationGO:00488631170.018
regulation of macromolecule biosynthetic processGO:00105562250.018
vascular endothelial growth factor receptor signaling pathwayGO:0048010130.018
aromatic compound biosynthetic processGO:00194382170.018
regulation of production of molecular mediator of immune responseGO:000270010.018
regulation of multicellular organismal processGO:00512392770.017
multicellular organism growthGO:003526440.017
regulation of cell communicationGO:00106462320.017
regulation of protein import into nucleusGO:004230620.017
negative regulation of biological processGO:00485193040.017
heart processGO:0003015710.017
regulation of anatomical structure morphogenesisGO:00226031300.017
regulation of phospholipase c activityGO:190027410.017
protein import into nucleusGO:000660630.017
nephron epithelium morphogenesisGO:007208810.017
enzyme linked receptor protein signaling pathwayGO:00071671060.017
ribonucleotide biosynthetic processGO:0009260200.017
regulation of signal transductionGO:00099662250.017
lymph vessel developmentGO:0001945270.017
organelle organizationGO:00069962270.017
sensory perception of chemical stimulusGO:000760630.017
multi organism processGO:00517041340.017
regulation of cellular macromolecule biosynthetic processGO:20001122220.017
cellular response to nutrient levelsGO:003166920.017
reactive oxygen species biosynthetic processGO:190340910.016
positive regulation of muscle cell differentiationGO:005114910.016
protein acetylationGO:000647320.016
defense responseGO:0006952470.016
protein importGO:001703830.016
cell morphogenesis involved in neuron differentiationGO:00486671630.016
nucleocytoplasmic transportGO:000691340.016
germ line stem cell maintenanceGO:003071820.016
positive regulation of epithelial cell migrationGO:001063420.016
reactive oxygen species metabolic processGO:007259360.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
positive regulation of immune effector processGO:000269930.016
lymphocyte proliferationGO:004665110.016
regulation of nucleocytoplasmic transportGO:004682220.016
regulation of muscle contractionGO:000693730.016
lymph vessel morphogenesisGO:0036303250.016
transcription from rna polymerase ii promoterGO:0006366800.016
vasculogenesisGO:0001570410.016
positive regulation of cellular component biogenesisGO:004408930.016
g protein coupled receptor signaling pathwayGO:0007186740.016
axonogenesisGO:00074091520.016
erk1 and erk2 cascadeGO:007037140.016
cellular nitrogen compound metabolic processGO:00346412900.016
positive regulation of cellular amine metabolic processGO:003324000.015
cellular response to molecule of bacterial originGO:007121930.015
autophagyGO:000691440.015
retina development in camera type eyeGO:00600411460.015
pericardium morphogenesisGO:000334410.015
cell matrix adhesionGO:000716040.015
inositol lipid mediated signalingGO:004801720.015
positive regulation of blood circulationGO:190352420.015
skeletal muscle organ developmentGO:0060538780.015
female gonad developmentGO:000858540.015
tissue remodelingGO:004877140.015
positive regulation of apoptotic signaling pathwayGO:200123510.015
single organism organelle organizationGO:19025891990.015
response to abiotic stimulusGO:00096281220.015
negative regulation of metabolic processGO:0009892860.015
neural retina developmentGO:0003407490.015
ventricular cardiac muscle tissue morphogenesisGO:005501020.015
protein metabolic processGO:00195381830.015
positive regulation of neural precursor cell proliferationGO:200017910.015
positive regulation of stress activated mapk cascadeGO:003287430.015
gene expressionGO:00104672520.015
cell part morphogenesisGO:00329902460.015
renal tubule morphogenesisGO:006133310.015
urogenital system developmentGO:0001655970.015
axon developmentGO:00615641660.015
positive regulation of secretionGO:005104710.014
ovulation cycle processGO:002260220.014
neurological system processGO:0050877620.014
inner ear developmentGO:00488391260.014
positive regulation of multicellular organismal processGO:0051240520.014
regulation of response to stimulusGO:00485832690.014
myeloid cell differentiationGO:0030099860.014
single organism nuclear importGO:190259330.014
response to other organismGO:0051707970.014
regulation of protein ubiquitinationGO:003139630.014
protein secretionGO:000930610.014
trabecula morphogenesisGO:006138320.014
positive regulation of cell activationGO:005086710.014
antimicrobial humoral responseGO:001973020.014
response to growth factorGO:0070848390.014
regulation of transcription from rna polymerase ii promoterGO:00063571140.014
cellular response to starvationGO:000926710.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
protein modification processGO:00362111000.014
positive regulation of biosynthetic processGO:0009891680.014
regulation of intracellular protein transportGO:003315730.014
connective tissue developmentGO:0061448990.014
regulation of locomotionGO:0040012550.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.014
regulation of carbohydrate metabolic processGO:000610940.014
regulation of cell matrix adhesionGO:000195210.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
cellular response to radiationGO:007147840.014
hematopoietic progenitor cell differentiationGO:0002244230.014
negative regulation of programmed cell deathGO:0043069580.014
nuclear transportGO:005116940.014
generation of neuronsGO:00486993850.014
signal transduction in absence of ligandGO:003803410.013
mesenchymal cell differentiationGO:0048762870.013
positive regulation of cell substrate adhesionGO:001081110.013
small molecule catabolic processGO:004428230.013
regulation of multicellular organism growthGO:004001440.013
negative regulation of protein complex assemblyGO:003133310.013
negative regulation of protein phosphorylationGO:000193340.013
mesenchymal cell proliferationGO:001046310.013
nitric oxide metabolic processGO:004620920.013
ear developmentGO:00435831270.013
kidney developmentGO:0001822920.013
regulation of skeletal muscle tissue developmentGO:004864140.013
positive regulation of nitrogen compound metabolic processGO:0051173690.013
patterning of blood vesselsGO:0001569150.013
compound eye developmentGO:004874920.013
membrane invaginationGO:001032410.013
production of molecular mediator of immune responseGO:000244020.013
response to bacteriumGO:0009617580.013
regulation of extrinsic apoptotic signaling pathwayGO:200123630.013
positive regulation of cellular metabolic processGO:0031325940.013
protein acylationGO:004354330.013
ventricular cardiac muscle tissue developmentGO:000322930.013
interspecies interaction between organismsGO:004441940.013
internal protein amino acid acetylationGO:000647520.013
gastrulationGO:00073692080.013
eye morphogenesisGO:00485921440.013
positive regulation of leukocyte migrationGO:000268720.013
cellular response to growth factor stimulusGO:0071363390.013
peptidyl serine phosphorylationGO:001810510.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
negative regulation of rna biosynthetic processGO:1902679450.012
chemotaxisGO:00069351040.012
peptide transportGO:001583310.012
regulation of protein targetingGO:190353320.012
regulation of biological qualityGO:00650082630.012
chordate embryonic developmentGO:00430092710.012
sensory perception of smellGO:000760820.012
response to nutrientGO:000758430.012
negative regulation of epithelial cell proliferationGO:005068010.012
positive regulation of lipid metabolic processGO:004583410.012
regulation of cell differentiationGO:00455951420.012
regulation of cell activationGO:005086510.012
hormone transportGO:000991420.012
mesenchymal cell developmentGO:0014031780.012
embryonic skeletal system developmentGO:0048706970.012
lipid catabolic processGO:001604240.012
negative regulation of protein kinase activityGO:000646940.012
regulation of cell motilityGO:2000145460.012
regulation of synaptic plasticityGO:004816710.012
negative regulation of macromolecule metabolic processGO:0010605760.012
tissue migrationGO:0090130370.012
cardiac atrium morphogenesisGO:000320920.012
cellular response to extracellular stimulusGO:003166820.012
positive regulation of gene expressionGO:0010628710.011
internal peptidyl lysine acetylationGO:001839320.011
regulation of cellular component movementGO:0051270550.011
notch signaling pathwayGO:0007219350.011
cell deathGO:00082191210.011
regulation of programmed cell deathGO:00430671010.011
epidermal cell differentiationGO:0009913360.011
hepaticobiliary system developmentGO:0061008980.011
regulation of growth rateGO:004000910.011
regulation of reproductive processGO:200024140.011
protein targeting to nucleusGO:004474430.011
cellular response to vascular endothelial growth factor stimulusGO:003592430.011
regulation of organ growthGO:004662030.011
endothelial cell proliferationGO:0001935110.011
regulation of cellular protein catabolic processGO:190336210.011
muscle structure developmentGO:00610611960.011
negative regulation of neural precursor cell proliferationGO:200017810.011
nitric oxide biosynthetic processGO:000680920.011
apoptotic processGO:00069151160.011
development of primary female sexual characteristicsGO:004654540.011
response to corticosteroidGO:003196010.011
cellular response to biotic stimulusGO:007121630.011
response to hypoxiaGO:0001666250.011
neuromast developmentGO:0048884460.011
mononuclear cell proliferationGO:003294310.011
muscle cell differentiationGO:00426921390.011
determination of bilateral symmetryGO:00098552040.011
cell cycle g1 s phase transitionGO:004484310.011
negative regulation of multicellular organismal processGO:0051241690.011
muscle organ developmentGO:00075171010.011
regulation of organelle assemblyGO:190211540.011
cell proliferationGO:0008283800.011
catechol containing compound metabolic processGO:000971220.011
negative regulation of transcription dna templatedGO:0045892450.011
positive regulation of stem cell proliferationGO:200064810.011
carboxylic acid catabolic processGO:004639530.011
cellular response to organic substanceGO:00713101050.011
cellular response to lipopolysaccharideGO:007122230.010
pericardium developmentGO:006003910.010
response to carbohydrateGO:000974330.010
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.010
chemosensory behaviorGO:000763510.010
phosphatidylinositol 3 kinase signalingGO:001406520.010
membrane fusionGO:006102520.010
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.010
phosphorus metabolic processGO:00067931090.010
positive regulation of macromolecule biosynthetic processGO:0010557590.010
positive regulation of secretion by cellGO:190353210.010
regulation of lipase activityGO:006019120.010
regulation of mesenchymal cell proliferationGO:001046410.010
regulation of circadian rhythmGO:004275240.010
nuclear importGO:005117030.010
neuron differentiationGO:00301823530.010
cell substrate junction assemblyGO:000704420.010
negative regulation of cellular processGO:00485232830.010
phagocytosis engulfmentGO:000691110.010
regulation of cell migration involved in sprouting angiogenesisGO:009004930.010
homeostatic processGO:00425921420.010
regulation of catalytic activityGO:0050790550.010
regulation of intracellular signal transductionGO:1902531570.010

pdgfb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.031
musculoskeletal system diseaseDOID:1700.025
disease of cellular proliferationDOID:1456600.014
nervous system diseaseDOID:86300.012
disease of metabolismDOID:001466700.010