Danio rerio

0 known processes

wwp1

WW domain containing E3 ubiquitin protein ligase 1

(Aliases: Smurf1,wu:fb30b12,zgc:66401)

wwp1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic organ developmentGO:00485683810.132
heart developmentGO:00075073130.111
larval developmentGO:000216420.107
ubiquitin dependent protein catabolic processGO:000651130.100
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.086
modification dependent protein catabolic processGO:001994130.084
meiotic nuclear divisionGO:000712640.083
locomotionGO:00400113130.075
response to chemicalGO:00422213200.075
muscle cell developmentGO:00550011150.072
regulation of metabolic processGO:00192223590.070
regulation of primary metabolic processGO:00800903110.069
proteolysis involved in cellular protein catabolic processGO:005160330.066
cellular component movementGO:00069283350.066
gtp metabolic processGO:004603940.065
aromatic compound biosynthetic processGO:00194382170.064
regulation of protein catabolic processGO:004217610.064
cellular nitrogen compound biosynthetic processGO:00442712180.063
modification dependent macromolecule catabolic processGO:004363230.062
meiotic cell cycle processGO:190304630.061
tube morphogenesisGO:00352393490.061
negative regulation of biological processGO:00485193040.060
Mouse
stem cell proliferationGO:007208940.059
peptidyl serine modificationGO:001820920.059
signal transductionGO:00071654550.057
specification of symmetryGO:00097992040.055
cellular nitrogen compound metabolic processGO:00346412900.055
cellular protein catabolic processGO:004425740.053
regulation of cellular macromolecule biosynthetic processGO:20001122220.051
cellular macromolecule biosynthetic processGO:00346452240.050
rna metabolic processGO:00160702190.050
regulation of carbohydrate metabolic processGO:000610940.050
determination of left right symmetryGO:00073681790.049
extrinsic apoptotic signaling pathwayGO:009719130.049
organelle assemblyGO:00709251100.049
cell surface receptor signaling pathwayGO:00071663250.048
biosynthetic processGO:00090582940.047
determination of bilateral symmetryGO:00098552040.047
embryonic organ morphogenesisGO:00485622740.046
regulation of biosynthetic processGO:00098892500.045
negative regulation of cellular processGO:00485232830.044
organelle organizationGO:00069962270.044
adult behaviorGO:003053420.044
hematopoietic or lymphoid organ developmentGO:00485341910.044
regulation of cellular carbohydrate metabolic processGO:001067540.044
macromolecule modificationGO:00434121110.042
Mouse
proteasomal protein catabolic processGO:001049820.042
morphogenesis of an epitheliumGO:00020093330.041
embryo development ending in birth or egg hatchingGO:00097922710.041
cellular protein modification processGO:00064641000.041
Mouse
organic substance biosynthetic processGO:19015762890.040
protein metabolic processGO:00195381830.040
Mouse
lipid storageGO:001991510.040
regulation of establishment of protein localizationGO:007020140.039
regulation of response to stimulusGO:00485832690.039
small molecule metabolic processGO:0044281770.039
maintenance of locationGO:005123540.038
regulation of macromolecule biosynthetic processGO:00105562250.038
single organism organelle organizationGO:19025891990.038
guanosine containing compound catabolic processGO:190106920.038
negative regulation of metabolic processGO:0009892860.037
macromolecule biosynthetic processGO:00090592270.036
stem cell divisionGO:001714510.036
sensory organ morphogenesisGO:00905962000.036
single organism biosynthetic processGO:0044711710.035
positive regulation of catabolic processGO:000989640.035
gastrulationGO:00073692080.035
gtp catabolic processGO:000618420.034
positive regulation of cellular component biogenesisGO:004408930.034
protein modification processGO:00362111000.033
Mouse
striated muscle cell differentiationGO:00511461290.033
nitrogen compound metabolic processGO:00068073190.033
agingGO:000756820.033
regulation of purine nucleotide catabolic processGO:003312120.033
gene expressionGO:00104672520.032
cellular aromatic compound metabolic processGO:00067252950.032
regulation of multicellular organism growthGO:004001440.032
cell part morphogenesisGO:00329902460.032
protein localization to nucleusGO:003450430.032
negative regulation of signal transductionGO:0009968940.032
striated muscle cell developmentGO:00550021080.032
regulation of multicellular organismal processGO:00512392770.032
Mouse
phosphate containing compound metabolic processGO:00067961080.031
golgi vesicle transportGO:004819330.031
cellular ketone metabolic processGO:0042180110.031
regulation of protein ubiquitinationGO:003139630.031
peptidyl serine phosphorylationGO:001810510.031
transcription dna templatedGO:00063511810.031
regulation of reproductive processGO:200024140.031
regulation of carbohydrate biosynthetic processGO:004325510.030
negative regulation of response to stimulusGO:00485851040.030
stem cell maintenanceGO:001982740.030
regulation of stem cell proliferationGO:007209120.029
nucleic acid templated transcriptionGO:00976591810.029
single organism metabolic processGO:00447102170.029
chordate embryonic developmentGO:00430092710.029
regulation of transcription from rna polymerase ii promoterGO:00063571140.029
regulation of nucleobase containing compound metabolic processGO:00192192500.029
rna biosynthetic processGO:00327741810.029
cell morphogenesisGO:00009022890.028
regulation of filopodium assemblyGO:005148920.028
regulation of gtp catabolic processGO:003312420.028
cellular biosynthetic processGO:00442492860.028
cell projection morphogenesisGO:00488582440.028
cellular component assemblyGO:00226071700.027
transcription from rna polymerase ii promoterGO:0006366800.027
regulation of macromolecule metabolic processGO:00602553170.027
regulation of nucleotide catabolic processGO:003081120.027
organic cyclic compound metabolic processGO:19013603010.027
response to alkaloidGO:004327920.026
activation of jun kinase activityGO:000725720.026
neurotransmitter transportGO:000683620.026
regulation of nitrogen compound metabolic processGO:00511712510.026
regulation of nucleoside metabolic processGO:000911820.026
regulation of signal transductionGO:00099662250.026
carbohydrate biosynthetic processGO:001605110.026
chemotaxisGO:00069351040.026
regulation of cellular biosynthetic processGO:00313262450.026
negative regulation of cell communicationGO:0010648960.026
regulation of protein modification by small protein conjugation or removalGO:190332030.025
establishment of protein localization to organelleGO:007259440.025
cellular component biogenesisGO:00440851780.025
heterocycle biosynthetic processGO:00181302150.025
organic acid metabolic processGO:0006082310.025
growthGO:00400071740.025
male meiosisGO:000714020.024
phagocytosisGO:000690930.024
cellular protein metabolic processGO:00442671290.024
Mouse
regulation of rna metabolic processGO:00512522240.024
regionalizationGO:00030022740.024
regulation of nucleic acid templated transcriptionGO:19035062130.024
programmed cell deathGO:00125011190.024
regulation of cell developmentGO:00602841000.024
axonogenesisGO:00074091520.024
cognitionGO:005089010.024
protein dephosphorylationGO:000647030.024
nucleic acid metabolic processGO:00903042440.024
multicellular organism growthGO:003526440.023
nucleobase containing compound biosynthetic processGO:00346542050.023
protein targeting to nucleusGO:004474430.023
rna localizationGO:000640340.023
digestive tract developmentGO:00485652650.023
negative regulation of biosynthetic processGO:0009890550.023
heterocycle metabolic processGO:00464832900.023
ion transmembrane transportGO:0034220910.023
response to hexoseGO:000974630.023
sensory organ developmentGO:00074233930.023
neurotransmitter secretionGO:000726920.023
production of molecular mediator of immune responseGO:000244020.022
negative regulation of tor signalingGO:003200720.022
nuclear transportGO:005116940.022
nucleic acid transportGO:005065720.022
positive regulation of purine nucleotide catabolic processGO:003312310.022
response to organic substanceGO:00100331530.022
regulation of cell projection assemblyGO:006049140.022
nucleocytoplasmic transportGO:000691340.021
regulation of cell communicationGO:00106462320.021
negative regulation of kinase activityGO:003367340.021
regulation of developmental processGO:00507932470.021
regulation of gene expressionGO:00104682650.021
regulation of peptidyl tyrosine phosphorylationGO:005073010.021
cellular macromolecule metabolic processGO:00442603910.021
Mouse
localization of cellGO:00516742440.021
regulation of nucleocytoplasmic transportGO:004682220.021
determination of heart left right asymmetryGO:00613711170.021
negative regulation of cellular metabolic processGO:0031324770.021
regulation of gtpase activityGO:004308720.021
phosphorus metabolic processGO:00067931090.021
skeletal system morphogenesisGO:00487051020.020
cellular response to chemical stimulusGO:00708871570.020
meiosis iGO:000712710.020
embryonic skeletal system developmentGO:0048706970.020
protein polyubiquitinationGO:000020940.020
regulation of cellular metabolic processGO:00313233200.020
negative regulation of protein phosphorylationGO:000193340.020
transportGO:00068102200.020
response to nutrientGO:000758430.020
positive regulation of transportGO:005105020.020
cellular response to oxygen levelsGO:007145310.020
regulation of cellular ketone metabolic processGO:001056570.020
negative regulation of signalingGO:0023057960.020
positive regulation of cell adhesionGO:004578510.019
muscle cell differentiationGO:00426921390.019
oxidation reduction processGO:0055114410.019
regulation of protein transportGO:005122330.019
cellular amino acid metabolic processGO:000652070.019
cellular response to decreased oxygen levelsGO:003629410.019
immune system processGO:00023762410.019
muscle structure developmentGO:00610611960.019
head developmentGO:00603223030.019
single organism nuclear importGO:190259330.019
post golgi vesicle mediated transportGO:000689210.019
protein import into nucleusGO:000660630.019
neuroblast proliferationGO:000740520.019
organic cyclic compound biosynthetic processGO:19013622230.019
negative regulation of macromolecule metabolic processGO:0010605760.018
guanosine containing compound metabolic processGO:190106840.018
cellular component morphogenesisGO:00329893360.018
heart loopingGO:0001947940.018
regulation of protein import into nucleusGO:004230620.018
positive regulation of canonical wnt signaling pathwayGO:009026340.018
cell substrate adhesionGO:003158940.018
vasculature developmentGO:00019442780.018
cell fate commitmentGO:0045165990.018
eye morphogenesisGO:00485921440.018
apoptotic processGO:00069151160.018
skeletal system developmentGO:00015011810.017
positive regulation of nucleoside metabolic processGO:004597910.017
protein importGO:001703830.017
compound eye developmentGO:004874920.017
signal transduction in absence of ligandGO:003803410.017
epithelial cell morphogenesisGO:000338220.017
liver developmentGO:0001889960.017
developmental growthGO:00485891660.017
camera type eye morphogenesisGO:00485931080.017
energy reserve metabolic processGO:000611220.017
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.017
cilium assemblyGO:0042384580.017
regulation of multicellular organismal developmentGO:20000262230.016
cell projection organizationGO:00300302840.016
mesenchyme developmentGO:00604851270.016
central nervous system developmentGO:00074173870.016
protein heterooligomerizationGO:005129110.016
cell morphogenesis involved in differentiationGO:00009041950.016
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.016
camera type eye developmentGO:00430102220.016
cellular component assembly involved in morphogenesisGO:00109271070.016
regulation of biomineral tissue developmentGO:007016720.016
regulation of cell activationGO:005086510.016
segmentationGO:0035282970.016
ear developmentGO:00435831270.016
regulation of dendrite developmentGO:005077330.016
regulation of protein targetingGO:190353320.016
negative regulation of catabolic processGO:000989530.016
regulation of intracellular protein transportGO:003315730.016
pyruvate metabolic processGO:000609010.016
renal tubule morphogenesisGO:006133310.016
oxoacid metabolic processGO:0043436310.016
carboxylic acid metabolic processGO:0019752220.016
embryonic heart tube morphogenesisGO:00031431080.016
digestive system developmentGO:00551232890.016
regulation of synapse assemblyGO:005196330.016
cellular response to hypoxiaGO:007145610.016
regulation of receptor mediated endocytosisGO:004825940.016
regulation of neural precursor cell proliferationGO:200017730.016
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.015
embryonic heart tube developmentGO:00350501330.015
regulation of protein complex assemblyGO:004325430.015
negative regulation of mapk cascadeGO:004340940.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
blood vessel developmentGO:00015682460.015
regulation of protein localization to nucleusGO:190018020.015
phosphatidylinositol 3 kinase signalingGO:001406520.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
cellular response to organic cyclic compoundGO:0071407380.015
nuclear importGO:005117030.015
regulation of cytoplasmic transportGO:190364940.015
cellular component disassemblyGO:002241110.015
positive regulation of neural precursor cell proliferationGO:200017910.015
positive regulation of nucleotide catabolic processGO:003081310.015
hypothalamus cell differentiationGO:002197940.015
amino acid transportGO:000686520.015
response to carbohydrateGO:000974330.015
negative regulation of wnt signaling pathwayGO:0030178300.015
regulation of cytokine productionGO:000181730.015
dna templated transcription elongationGO:000635430.015
synaptic growth at neuromuscular junctionGO:005112420.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
cell matrix adhesionGO:000716040.014
negative regulation of defense responseGO:003134820.014
regulation of circadian rhythmGO:004275240.014
deathGO:00162651210.014
regulation of cellular amine metabolic processGO:003323800.014
positive regulation of gtpase activityGO:004354710.014
cytokinesisGO:000091030.014
inositol lipid mediated signalingGO:004801720.014
response to drugGO:004249330.014
positive regulation of cellular catabolic processGO:003133130.014
regulation of epithelial cell proliferationGO:005067830.013
meiotic spindle organizationGO:000021210.013
response to monosaccharideGO:003428430.013
erk1 and erk2 cascadeGO:007037140.013
regulation of protein bindingGO:004339330.013
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.013
cellular response to extracellular stimulusGO:003166820.013
positive regulation of gtp catabolic processGO:003312610.013
positive regulation of protein kinase b signalingGO:005189710.013
response to abiotic stimulusGO:00096281220.013
neuron projection developmentGO:00311751800.013
establishment of protein localization to plasma membraneGO:009000210.013
centrosome organizationGO:005129710.013
synaptic vesicle transportGO:004848910.013
establishment of rna localizationGO:005123630.013
negative regulation of protein kinase activityGO:000646940.013
cell migrationGO:00164772370.013
meiotic chromosome segregationGO:004513230.013
positive regulation of protein complex assemblyGO:003133420.013
system processGO:00030081850.013
regulation of cellular component organizationGO:0051128860.013
germ line stem cell maintenanceGO:003071820.013
regulation of transcription dna templatedGO:00063552130.013
gland developmentGO:00487321430.013
membrane invaginationGO:001032410.013
microtubule based processGO:0007017600.013
embryonic skeletal joint developmentGO:007249830.013
nucleobase containing compound transportGO:001593120.012
negative regulation of cytokine mediated signaling pathwayGO:000196020.012
regulation of cell differentiationGO:00455951420.012
muscle cell migrationGO:001481240.012
positive regulation of cell substrate adhesionGO:001081110.012
primary neural tube formationGO:001402010.012
regulation of intracellular phGO:005145310.012
post embryonic organ developmentGO:004856940.012
regulation of stem cell differentiationGO:200073640.012
regulation of signalingGO:00230512350.012
positive regulation of macromolecule metabolic processGO:0010604930.012
regulation of response to nutrient levelsGO:003210710.012
multi organism processGO:00517041340.012
organonitrogen compound metabolic processGO:1901564740.012
behaviorGO:0007610740.012
regulation of jak stat cascadeGO:004642530.012
regulation of dna templated transcription elongationGO:003278430.012
regulation of organelle assemblyGO:190211540.012
lymphocyte proliferationGO:004665110.012
response to stressGO:00069502630.012
foregut morphogenesisGO:000744040.012
response to vitaminGO:003327330.012
positive regulation of cytoskeleton organizationGO:005149530.012
positive regulation of response to stimulusGO:0048584800.012
epithelial tube morphogenesisGO:00605621480.012
regulation of synapse organizationGO:005080730.012
establishment of synaptic vesicle localizationGO:009748010.012
embryonic skeletal joint morphogenesisGO:006027230.012
regulation of bone mineralizationGO:003050020.011
stem cell differentiationGO:00488631170.011
internal protein amino acid acetylationGO:000647520.011
negative regulation of epithelial cell proliferationGO:005068010.011
carbohydrate derivative metabolic processGO:1901135610.011
regulation of cellular amino acid metabolic processGO:000652100.011
positive regulation of cell cycleGO:004578730.011
glucose homeostasisGO:004259310.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
gastrulation with mouth forming secondGO:0001702440.011
macromolecular complex assemblyGO:0065003350.011
chemosensory behaviorGO:000763510.011
cartilage developmentGO:0051216960.011
regulation of cell deathGO:00109411030.011
blood vessel morphogenesisGO:00485142160.011
regulation of cell substrate adhesionGO:001081010.011
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.011
dorsal ventral pattern formationGO:00099531250.011
negative regulation of neural precursor cell proliferationGO:200017810.011
neuron differentiationGO:00301823530.011
transcription elongation from rna polymerase ii promoterGO:000636830.011
cellular response to starvationGO:000926710.011
hepaticobiliary system developmentGO:0061008980.011
nuclear exportGO:005116810.011
er to golgi vesicle mediated transportGO:000688810.010
somatic stem cell maintenanceGO:003501910.010
spindle assemblyGO:005122520.010
regulation of bindingGO:005109830.010
negative regulation of protein complex assemblyGO:003133310.010
cellular response to nutrient levelsGO:003166920.010
embryonic skeletal system morphogenesisGO:0048704930.010
positive regulation of cellular processGO:00485222010.010
nuclear migrationGO:000709730.010
regulation of embryonic developmentGO:0045995470.010
pole plasm assemblyGO:000731540.010
macromolecular complex disassemblyGO:003298410.010
negative regulation of cytoplasmic transportGO:190365020.010
regulation of cellular protein catabolic processGO:190336210.010
osteoclast differentiationGO:003031610.010
generation of neuronsGO:00486993850.010
regulation of blood vessel sizeGO:005088020.010
regulation of programmed cell deathGO:00430671010.010
proximal distal pattern formationGO:000995410.010
microtubule organizing center organizationGO:003102310.010
negative regulation of immune responseGO:005077720.010
hormone secretionGO:004687920.010
regulation of skeletal muscle fiber developmentGO:004874220.010

wwp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.025
disease of anatomical entityDOID:700.025
nervous system diseaseDOID:86300.016
cancerDOID:16200.016
organ system cancerDOID:005068600.016
disease of cellular proliferationDOID:1456600.016
disease of metabolismDOID:001466700.012