Danio rerio

64 known processes

men1

multiple endocrine neoplasia type 1 and multiple endocrine neoplasia I

(Aliases: wu:fc44c03,zgc:110510)

men1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular component morphogenesisGO:00329893360.217
hematopoietic or lymphoid organ developmentGO:00485341910.188
cellular biosynthetic processGO:00442492860.146
sequestering of metal ionGO:005123830.140
immune system developmentGO:00025201910.136
cellular macromolecule biosynthetic processGO:00346452240.134
central nervous system developmentGO:00074173870.111
digestive tract developmentGO:00485652650.106
organelle organizationGO:00069962270.103
organic substance biosynthetic processGO:19015762890.097
digestive tract morphogenesisGO:00485462310.095
agingGO:000756820.093
cell projection organizationGO:00300302840.093
morphogenesis of an epitheliumGO:00020093330.093
larval developmentGO:000216420.091
nucleobase containing compound biosynthetic processGO:00346542050.089
calcium ion transmembrane transportGO:0070588130.088
aromatic compound biosynthetic processGO:00194382170.084
neuron differentiationGO:00301823530.083
positive regulation of map kinase activityGO:004340630.082
regulation of macromolecule biosynthetic processGO:00105562250.075
sequestering of calcium ionGO:005120830.074
hemopoiesisGO:00300971830.072
immune system processGO:00023762410.071
adult behaviorGO:003053420.071
negative regulation of sequestering of calcium ionGO:005128340.070
cognitionGO:005089010.070
regulation of transcription dna templatedGO:00063552130.070
calcium ion transport into cytosolGO:006040230.068
brain developmentGO:00074202930.067
regulation of epithelial cell proliferationGO:005067830.066
single organism metabolic processGO:00447102170.065
regulation of rna biosynthetic processGO:20011412130.063
cellular macromolecule metabolic processGO:00442603910.062
stem cell fate commitmentGO:004886510.061
protein dephosphorylationGO:000647030.061
positive regulation of transportGO:005105020.058
regulation of cellular biosynthetic processGO:00313262450.058
regulation of cell communicationGO:00106462320.057
heterocycle biosynthetic processGO:00181302150.056
regulation of multicellular organism growthGO:004001440.055
cell projection morphogenesisGO:00488582440.055
lipid homeostasisGO:005508830.054
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.054
organic cyclic compound metabolic processGO:19013603010.054
cell motilityGO:00488702440.054
positive regulation of epithelial cell proliferationGO:005067910.053
regulation of biological qualityGO:00650082630.053
release of sequestered calcium ion into cytosolGO:005120930.053
myeloid cell differentiationGO:0030099860.052
positive regulation of cytosolic calcium ion concentrationGO:000720440.052
multicellular organism growthGO:003526440.052
transportGO:00068102200.052
programmed cell deathGO:00125011190.051
positive regulation of biological processGO:00485182530.050
cellular aromatic compound metabolic processGO:00067252950.049
cellular nitrogen compound metabolic processGO:00346412900.049
stem cell differentiationGO:00488631170.049
regulation of biosynthetic processGO:00098892500.048
chromosome organizationGO:0051276310.048
sensory organ developmentGO:00074233930.047
regulation of sequestering of calcium ionGO:005128240.047
cell cycle g1 s phase transitionGO:004484310.046
digestive system developmentGO:00551232890.045
locomotionGO:00400113130.044
signal transductionGO:00071654550.043
regulation of gene expressionGO:00104682650.043
inorganic ion transmembrane transportGO:0098660570.043
regulation of dna replicationGO:000627530.042
cell morphogenesis involved in differentiationGO:00009041950.042
cellular component movementGO:00069283350.042
inorganic cation transmembrane transportGO:0098662500.042
regulation of protein transportGO:005122330.042
protein targeting to nucleusGO:004474430.042
cytosolic calcium ion transportGO:006040130.042
developmental growth involved in morphogenesisGO:0060560860.042
axon developmentGO:00615641660.041
b cell differentiationGO:003018310.040
cellular nitrogen compound biosynthetic processGO:00442712180.040
regionalizationGO:00030022740.040
macromolecule biosynthetic processGO:00090592270.040
angiogenesisGO:00015251580.039
g1 s transition of mitotic cell cycleGO:000008210.039
homeostasis of number of cellsGO:0048872620.038
regulation of signalingGO:00230512350.038
regulation of macromolecule metabolic processGO:00602553170.037
nuclear importGO:005117030.037
rna biosynthetic processGO:00327741810.035
regulation of membrane potentialGO:0042391230.035
single organism nuclear importGO:190259330.035
embryonic cranial skeleton morphogenesisGO:0048701900.034
regulation of apoptotic processGO:0042981980.034
extrinsic apoptotic signaling pathwayGO:009719130.033
mitotic dna integrity checkpointGO:004477440.033
nucleic acid templated transcriptionGO:00976591810.033
regulation of cell shapeGO:000836010.033
nucleic acid metabolic processGO:00903042440.033
positive regulation of cellular component biogenesisGO:004408930.033
post embryonic organ developmentGO:004856940.033
regulation of erk1 and erk2 cascadeGO:007037240.032
cellular hormone metabolic processGO:0034754190.032
rna metabolic processGO:00160702190.032
establishment of localizationGO:00512342440.031
homeostatic processGO:00425921420.031
positive regulation of secretion by cellGO:190353210.031
regulation of filopodium assemblyGO:005148920.031
cellular response to extracellular stimulusGO:003166820.031
cellular response to nutrient levelsGO:003166920.031
cellular protein catabolic processGO:004425740.030
cell migrationGO:00164772370.030
heart developmentGO:00075073130.030
vasculature developmentGO:00019442780.030
positive regulation of cell cycleGO:004578730.030
stem cell maintenanceGO:001982740.029
biosynthetic processGO:00090582940.029
regulation of establishment of planar polarityGO:009017540.029
protein import into nucleusGO:000660630.029
negative regulation of apoptotic processGO:0043066550.028
regulation of establishment of protein localizationGO:007020140.028
cation transportGO:0006812810.028
negative regulation of cellular processGO:00485232830.028
phagocytosisGO:000690930.028
cell agingGO:000756920.028
organonitrogen compound metabolic processGO:1901564740.028
nuclear transportGO:005116940.027
cell part morphogenesisGO:00329902460.027
gene expressionGO:00104672520.026
positive regulation of metabolic processGO:00098931080.026
positive regulation of secretionGO:005104710.026
establishment of protein localization to organelleGO:007259440.026
embryonic organ developmentGO:00485683810.026
amine metabolic processGO:000930820.026
pancreas developmentGO:0031016840.026
cell surface receptor signaling pathwayGO:00071663250.026
positive regulation of gene expressionGO:0010628710.026
regulation of developmental processGO:00507932470.026
transcription from rna polymerase ii promoterGO:0006366800.025
positive regulation of signalingGO:0023056560.025
ion transmembrane transportGO:0034220910.025
proteolysis involved in cellular protein catabolic processGO:005160330.025
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.025
b cell activationGO:004211320.025
regulation of cellular macromolecule biosynthetic processGO:20001122220.025
regulation of primary metabolic processGO:00800903110.024
transcription dna templatedGO:00063511810.024
oxoacid metabolic processGO:0043436310.024
alpha amino acid metabolic processGO:190160530.024
neuron developmentGO:00486662620.024
positive regulation of apoptotic signaling pathwayGO:200123510.024
small molecule catabolic processGO:004428230.024
heterocycle metabolic processGO:00464832900.024
mesenchyme developmentGO:00604851270.023
determination of heart left right asymmetryGO:00613711170.023
neuromast developmentGO:0048884460.023
proteasomal protein catabolic processGO:001049820.023
oocyte maturationGO:000155640.023
metal ion homeostasisGO:0055065260.023
generation of neuronsGO:00486993850.023
ras protein signal transductionGO:000726570.023
transmembrane transportGO:00550851200.023
organic acid metabolic processGO:0006082310.023
response to radiationGO:0009314510.023
wnt signaling pathwayGO:0016055800.023
embryonic digestive tract developmentGO:004856640.023
regulation of wound healingGO:006104120.022
protein metabolic processGO:00195381830.022
negative regulation of biological processGO:00485193040.022
regulation of rna metabolic processGO:00512522240.022
multicellular organismal signalingGO:0035637220.022
regulation of hormone secretionGO:004688320.022
regulation of programmed cell deathGO:00430671010.022
macromolecule modificationGO:00434121110.022
specification of symmetryGO:00097992040.022
ion transportGO:00068111140.022
heart loopingGO:0001947940.022
regulation of nucleic acid templated transcriptionGO:19035062130.021
chemosensory behaviorGO:000763510.021
erythrocyte differentiationGO:0030218540.021
regulation of metabolic processGO:00192223590.021
somatic muscle developmentGO:000752540.021
cell projection assemblyGO:0030031640.021
neuron projection morphogenesisGO:00488121610.021
nucleocytoplasmic transportGO:000691340.021
head developmentGO:00603223030.021
protein localization to nucleusGO:003450430.021
cation transmembrane transportGO:0098655650.021
maintenance of locationGO:005123540.021
ventricular cardiac muscle tissue developmentGO:000322930.021
carboxylic acid metabolic processGO:0019752220.021
ameboidal type cell migrationGO:00016671430.020
regulation of reproductive processGO:200024140.020
cellular amine metabolic processGO:004410620.020
ear developmentGO:00435831270.020
kupffer s vesicle developmentGO:0070121500.020
localization of cellGO:00516742440.020
regulation of nervous system developmentGO:0051960900.020
mesenchymal cell differentiationGO:0048762870.020
cellular respirationGO:004533330.020
regulation of protein catabolic processGO:004217610.020
regulation of cellular amine metabolic processGO:003323800.020
cell deathGO:00082191210.020
leukocyte homeostasisGO:000177620.020
regulation of cell activationGO:005086510.019
mesenchymal cell developmentGO:0014031780.019
negative regulation of cellular catabolic processGO:003133030.019
dicarboxylic acid metabolic processGO:004364810.019
positive regulation of cellular processGO:00485222010.019
negative regulation of dna metabolic processGO:005105340.019
positive regulation of wound healingGO:009030310.019
positive regulation of erk1 and erk2 cascadeGO:007037420.019
regulation of cell differentiationGO:00455951420.019
meiotic nuclear divisionGO:000712640.019
skeletal system developmentGO:00015011810.018
regulation of extrinsic apoptotic signaling pathwayGO:200123630.018
organic cyclic compound biosynthetic processGO:19013622230.018
intracellular signal transductionGO:0035556850.018
tissue remodelingGO:004877140.018
mitotic cell cycleGO:0000278640.018
positive regulation of nucleic acid templated transcriptionGO:1903508570.018
regulation of cellular ketone metabolic processGO:001056570.018
single organism transportGO:00447652060.018
activation of mapk activityGO:000018730.017
erk1 and erk2 cascadeGO:007037140.017
positive regulation of dna metabolic processGO:005105410.017
protein importGO:001703830.017
carbohydrate biosynthetic processGO:001605110.017
chromatin organizationGO:0006325220.017
periodic partitioningGO:000736510.017
positive regulation of cellular biosynthetic processGO:0031328680.017
response to uvGO:000941130.017
cellular amino acid metabolic processGO:000652070.017
lipid storageGO:001991510.016
cell proliferationGO:0008283800.016
compound eye developmentGO:004874920.016
blood vessel developmentGO:00015682460.016
single organism organelle organizationGO:19025891990.016
negative regulation of epithelial cell proliferationGO:005068010.016
regulation of response to stimulusGO:00485832690.016
erythrocyte homeostasisGO:0034101550.016
mitotic dna damage checkpointGO:004477340.016
determination of left right symmetryGO:00073681790.016
regulation of cellular metabolic processGO:00313233200.016
apoptotic processGO:00069151160.016
regulation of nucleobase containing compound metabolic processGO:00192192500.015
blood vessel morphogenesisGO:00485142160.015
neurological system processGO:0050877620.015
protein stabilizationGO:005082120.015
regulation of mitotic cell cycleGO:0007346250.015
lateral line developmentGO:0048882660.015
regulation of cellular amino acid metabolic processGO:000652100.015
regulation of cell substrate adhesionGO:001081010.015
segment polarity determinationGO:000736710.015
embryonic hemopoiesisGO:0035162530.015
negative regulation of catabolic processGO:000989530.015
cellular protein metabolic processGO:00442671290.015
regulation of chromosome segregationGO:005198310.015
action potentialGO:0001508190.015
regulation of cytoplasmic transportGO:190364940.015
production of molecular mediator of immune responseGO:000244020.015
cell cycleGO:0007049930.015
protein modification processGO:00362111000.015
cell cell signalingGO:0007267520.014
gliogenesisGO:0042063450.014
anterior posterior pattern specificationGO:00099521520.014
regulation of signal transductionGO:00099662250.014
regulation of multicellular organismal processGO:00512392770.014
phosphorylationGO:0016310690.014
negative regulation of programmed cell deathGO:0043069580.014
double strand break repairGO:000630230.014
mesenchymal cell proliferationGO:001046310.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
multi organism processGO:00517041340.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
modification dependent macromolecule catabolic processGO:004363230.014
regulation of meiotic cell cycleGO:005144510.014
regulation of cell deathGO:00109411030.013
cellular response to radiationGO:007147840.013
rho protein signal transductionGO:000726650.013
metal ion transportGO:0030001580.013
stem cell developmentGO:0048864820.013
startle responseGO:000196440.013
single organism biosynthetic processGO:0044711710.013
cellular ketone metabolic processGO:0042180110.013
regulation of cell projection assemblyGO:006049140.013
autophagyGO:000691440.013
fin developmentGO:0033333770.013
g protein coupled receptor signaling pathwayGO:0007186740.013
regulation of cell cycleGO:0051726520.013
negative regulation of dna replicationGO:000815620.013
nitrogen compound metabolic processGO:00068073190.013
organonitrogen compound biosynthetic processGO:1901566470.013
small molecule metabolic processGO:0044281770.013
multicellular organismal metabolic processGO:004423620.013
positive regulation of multi organism processGO:004390230.013
cellular localizationGO:0051641970.013
regulation of cellular component movementGO:0051270550.013
tube morphogenesisGO:00352393490.013
cellular response to external stimulusGO:007149620.013
cellular metal ion homeostasisGO:0006875160.012
regulation of inhibitory postsynaptic membrane potentialGO:006008010.012
regulation of localizationGO:00328791040.012
negative regulation of ras protein signal transductionGO:004658010.012
axonogenesisGO:00074091520.012
cell maturationGO:0048469230.012
deathGO:00162651210.012
negative regulation of leukocyte differentiationGO:190210610.012
embryonic heart tube morphogenesisGO:00031431080.012
cellular response to starvationGO:000926710.012
negative regulation of cell deathGO:0060548600.012
ion homeostasisGO:0050801410.012
dna metabolic processGO:0006259270.012
actin filament based processGO:0030029640.012
bone remodelingGO:004684920.012
regulation of synaptic plasticityGO:004816710.012
cellular component disassemblyGO:002241110.012
regulation of synapse organizationGO:005080730.012
cellular component assemblyGO:00226071700.012
inner ear developmentGO:00488391260.012
melanin metabolic processGO:000658220.012
positive regulation of reproductive processGO:200024320.012
negative regulation of cell differentiationGO:0045596460.012
negative regulation of myeloid cell differentiationGO:004563810.012
meiotic cell cycle processGO:190304630.012
calcium ion homeostasisGO:0055074190.012
response to stressGO:00069502630.011
negative regulation of cytoplasmic transportGO:190365020.011
regulation of intracellular protein transportGO:003315730.011
regulation of bone remodelingGO:004685020.011
regulation of postsynaptic membrane potentialGO:006007810.011
gtp catabolic processGO:000618420.011
cellular response to hypoxiaGO:007145610.011
positive regulation of lipid metabolic processGO:004583410.011
growthGO:00400071740.011
positive regulation of mesenchymal cell proliferationGO:000205310.011
myeloid cell homeostasisGO:0002262560.011
sensory perception of chemical stimulusGO:000760630.011
myofibril assemblyGO:0030239480.011
cellular response to organic cyclic compoundGO:0071407380.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
actin filament based movementGO:003004810.011
neuron neuron synaptic transmissionGO:000727010.011
negative regulation of secretion by cellGO:190353120.011
embryonic organ morphogenesisGO:00485622740.011
response to drugGO:004249330.011
cellular ion homeostasisGO:0006873170.011
heart processGO:0003015710.011
membrane invaginationGO:001032410.011
negative regulation of macromolecule biosynthetic processGO:0010558480.011
small gtpase mediated signal transductionGO:000726480.011
negative regulation of protein transportGO:005122430.011
hormone secretionGO:004687920.011
cell morphogenesisGO:00009022890.011
regulation of calcium ion transportGO:005192420.011
mitotic g2 m transition checkpointGO:004481830.011
rna 3 end processingGO:003112320.011
negative regulation of metabolic processGO:0009892860.011
cellular response to oxygen levelsGO:007145310.011
neural crest cell differentiationGO:0014033720.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
cellular amide metabolic processGO:004360340.011
positive regulation of response to stimulusGO:0048584800.010
stem cell proliferationGO:007208940.010
phagocytosis engulfmentGO:000691110.010
cation homeostasisGO:0055080330.010
protein acylationGO:004354330.010
positive regulation of nitrogen compound metabolic processGO:0051173690.010
calcium ion transportGO:0006816180.010
regulation of transporter activityGO:003240920.010
ventricular cardiac muscle tissue morphogenesisGO:005501020.010
positive regulation of nucleobase containing compound metabolic processGO:0045935690.010
negative regulation of hormone secretionGO:004688820.010
g2 dna damage checkpointGO:003157230.010
positive regulation of multicellular organismal processGO:0051240520.010
regulation of stem cell proliferationGO:007209120.010
heart morphogenesisGO:00030071560.010
meiosis iGO:000712710.010
regulation of catalytic activityGO:0050790550.010

men1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.046
cancerDOID:16200.030
organ system cancerDOID:005068600.021
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.013