Danio rerio

0 known processes

aph1b

anterior pharynx defective 1B

(Aliases: APH1A,wu:fi53a04,psfl,wu:fc41h05)

aph1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.215
embryo development ending in birth or egg hatchingGO:00097922710.141
larval developmentGO:000216420.137
signal transductionGO:00071654550.117
immune system processGO:00023762410.084
cell projection morphogenesisGO:00488582440.083
proteolysis involved in cellular protein catabolic processGO:005160330.081
cell projection organizationGO:00300302840.081
negative regulation of biological processGO:00485193040.077
somitogenesisGO:0001756870.071
programmed cell deathGO:00125011190.069
cell surface receptor signaling pathwayGO:00071663250.065
single organism transportGO:00447652060.065
digestive system developmentGO:00551232890.063
negative regulation of cellular processGO:00485232830.062
chordate embryonic developmentGO:00430092710.061
response to chemicalGO:00422213200.059
positive regulation of transportGO:005105020.058
regulation of nitrogen compound metabolic processGO:00511712510.058
cellular component morphogenesisGO:00329893360.057
cellular amine metabolic processGO:004410620.057
regulation of apoptotic processGO:0042981980.055
locomotionGO:00400113130.054
establishment of protein localization to organelleGO:007259440.052
generation of neuronsGO:00486993850.050
nitrogen compound metabolic processGO:00068073190.050
regulation of synapse organizationGO:005080730.048
cellular protein catabolic processGO:004425740.048
protein import into nucleusGO:000660630.048
multicellular organism growthGO:003526440.048
amine metabolic processGO:000930820.048
axon developmentGO:00615641660.047
ubiquitin dependent protein catabolic processGO:000651130.047
embryonic organ morphogenesisGO:00485622740.046
anterior posterior pattern specificationGO:00099521520.046
somite developmentGO:0061053960.046
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.044
heart developmentGO:00075073130.044
regionalizationGO:00030022740.044
protein localization to nucleusGO:003450430.043
negative regulation of catabolic processGO:000989530.043
proteasomal protein catabolic processGO:001049820.042
positive regulation of biological processGO:00485182530.041
digestive tract developmentGO:00485652650.041
single organism localizationGO:19025782250.040
cellular amino acid metabolic processGO:000652070.040
neuron developmentGO:00486662620.040
skeletal system developmentGO:00015011810.040
regulation of developmental processGO:00507932470.040
cell part morphogenesisGO:00329902460.039
regulation of synapse assemblyGO:005196330.039
regulation of extrinsic apoptotic signaling pathwayGO:200123630.039
post embryonic morphogenesisGO:000988640.039
modification dependent protein catabolic processGO:001994130.039
developmental growthGO:00485891660.038
regulation of multicellular organism growthGO:004001440.038
response to nutrientGO:000758430.038
organonitrogen compound metabolic processGO:1901564740.037
cellular ketone metabolic processGO:0042180110.036
synaptic growth at neuromuscular junctionGO:005112420.036
organic acid metabolic processGO:0006082310.036
regulation of programmed cell deathGO:00430671010.035
small molecule metabolic processGO:0044281770.035
ion transmembrane transportGO:0034220910.035
embryonic limb morphogenesisGO:003032620.035
response to drugGO:004249330.034
gtp metabolic processGO:004603940.034
single organism metabolic processGO:00447102170.034
cellular nitrogen compound metabolic processGO:00346412900.034
negative regulation of cellular catabolic processGO:003133030.034
regulation of macromolecule metabolic processGO:00602553170.033
regulation of cellular macromolecule biosynthetic processGO:20001122220.032
gtp catabolic processGO:000618420.032
hemopoiesisGO:00300971830.032
regulation of cell deathGO:00109411030.032
embryonic skeletal system morphogenesisGO:0048704930.031
fertilizationGO:000956630.031
exocytosisGO:000688710.031
cell morphogenesisGO:00009022890.031
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.031
cell morphogenesis involved in differentiationGO:00009041950.031
rna biosynthetic processGO:00327741810.031
somatic muscle developmentGO:000752540.030
cellular response to nutrient levelsGO:003166920.030
oxoacid metabolic processGO:0043436310.030
dorsal ventral pattern formationGO:00099531250.030
regulation of synaptic growth at neuromuscular junctionGO:000858210.030
growthGO:00400071740.030
regulation of signal transductionGO:00099662250.030
regulation of cellular amine metabolic processGO:003323800.030
mitochondrial transportGO:000683920.030
muscle structure developmentGO:00610611960.030
adult behaviorGO:003053420.029
protein targeting to nucleusGO:004474430.029
regulation of cellular ketone metabolic processGO:001056570.029
epithelial tube morphogenesisGO:00605621480.029
regulation of epithelial cell proliferationGO:005067830.029
segmentationGO:0035282970.029
post embryonic organ developmentGO:004856940.029
regulation of biological qualityGO:00650082630.029
cellular nitrogen compound biosynthetic processGO:00442712180.029
regulation of cellular amino acid metabolic processGO:000652100.028
organic cyclic compound metabolic processGO:19013603010.028
rna metabolic processGO:00160702190.028
guanosine containing compound metabolic processGO:190106840.027
embryonic skeletal system developmentGO:0048706970.027
cellular amide metabolic processGO:004360340.027
phagocytosisGO:000690930.027
regulation of synaptic plasticityGO:004816710.027
guanosine containing compound catabolic processGO:190106920.027
response to stressGO:00069502630.027
cellular response to external stimulusGO:007149620.026
regulation of peptidyl tyrosine phosphorylationGO:005073010.026
atp catabolic processGO:000620040.026
mitochondrion organizationGO:000700540.026
organic substance biosynthetic processGO:19015762890.026
regulation of signalingGO:00230512350.026
positive regulation of cellular catabolic processGO:003133130.026
regulation of reproductive processGO:200024140.026
regulation of cell communicationGO:00106462320.025
gastrulationGO:00073692080.025
single organism nuclear importGO:190259330.025
embryonic organ developmentGO:00485683810.025
morphogenesis of an epitheliumGO:00020093330.025
regulation of metal ion transportGO:001095940.025
biosynthetic processGO:00090582940.024
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.024
protein importGO:001703830.024
extrinsic apoptotic signaling pathwayGO:009719130.024
multi organism processGO:00517041340.024
peptidyl serine phosphorylationGO:001810510.024
regulation of protein bindingGO:004339330.024
neuron projection developmentGO:00311751800.024
negative regulation of cell deathGO:0060548600.024
apoptotic processGO:00069151160.024
immune system developmentGO:00025201910.024
peptide metabolic processGO:000651810.023
autophagyGO:000691440.023
ribonucleoside monophosphate catabolic processGO:000915840.023
cellular biosynthetic processGO:00442492860.023
cellular response to extracellular stimulusGO:003166820.023
regulation of cell shapeGO:000836010.023
regulation of establishment of protein localizationGO:007020140.023
carbohydrate derivative biosynthetic processGO:1901137430.023
carboxylic acid metabolic processGO:0019752220.023
regulation of multicellular organismal processGO:00512392770.023
cellular protein metabolic processGO:00442671290.023
nucleobase containing compound biosynthetic processGO:00346542050.023
positive regulation of apoptotic signaling pathwayGO:200123510.022
response to external stimulusGO:00096052640.022
cell deathGO:00082191210.022
notch signaling pathwayGO:0007219350.022
glial cell migrationGO:000834730.022
negative regulation of reproductive processGO:200024230.022
transcription dna templatedGO:00063511810.022
regulation of gtpase activityGO:004308720.022
positive regulation of cell cycleGO:004578730.021
phosphate containing compound metabolic processGO:00067961080.021
purine ribonucleoside monophosphate catabolic processGO:000916940.021
regulation of purine nucleotide catabolic processGO:003312120.021
maintenance of locationGO:005123540.021
neurotransmitter secretionGO:000726920.021
tube morphogenesisGO:00352393490.021
cellular component movementGO:00069283350.021
neurotransmitter transportGO:000683620.021
deathGO:00162651210.021
nuclear importGO:005117030.021
regulation of bindingGO:005109830.021
regulation of protein transportGO:005122330.021
embryonic heart tube morphogenesisGO:00031431080.021
regulation of multicellular organismal developmentGO:20000262230.021
organelle organizationGO:00069962270.021
cell cycle arrestGO:000705010.021
gene expressionGO:00104672520.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
homeostatic processGO:00425921420.020
lymph vessel morphogenesisGO:0036303250.020
modification dependent macromolecule catabolic processGO:004363230.020
positive regulation of catabolic processGO:000989640.020
establishment of localizationGO:00512342440.020
lipid storageGO:001991510.020
neuron deathGO:0070997210.020
blood vessel developmentGO:00015682460.020
cell growthGO:0016049570.020
receptor recyclingGO:000188140.020
negative regulation of protein kinase activityGO:000646940.020
wnt signaling pathwayGO:0016055800.019
nucleic acid metabolic processGO:00903042440.019
establishment of protein localization to plasma membraneGO:009000210.019
negative regulation of programmed cell deathGO:0043069580.019
peptidyl serine modificationGO:001820920.019
digestive tract morphogenesisGO:00485462310.019
neuron projection morphogenesisGO:00488121610.019
detection of temperature stimulusGO:001604800.019
embryonic cranial skeleton morphogenesisGO:0048701900.019
adherens junction organizationGO:003433240.019
regulation of transcription dna templatedGO:00063552130.019
cellular component assemblyGO:00226071700.019
lateral inhibitionGO:004633110.019
negative regulation of protein phosphorylationGO:000193340.018
homeostasis of number of cellsGO:0048872620.018
positive regulation of nucleoside metabolic processGO:004597910.018
determination of left right symmetryGO:00073681790.018
positive regulation of chromatin modificationGO:190331010.018
cellular component disassemblyGO:002241110.018
response to organic substanceGO:00100331530.018
cellular macromolecule metabolic processGO:00442603910.018
regulation of cytoplasmic transportGO:190364940.018
regulation of response to stimulusGO:00485832690.018
establishment of localization in cellGO:0051649770.018
eye developmentGO:00016542770.018
hematopoietic or lymphoid organ developmentGO:00485341910.018
embryonic heart tube developmentGO:00350501330.018
nuclear transportGO:005116940.018
cellular macromolecule biosynthetic processGO:00346452240.018
purine nucleoside monophosphate catabolic processGO:000912840.018
positive regulation of cellular amine metabolic processGO:003324000.018
mesenchyme developmentGO:00604851270.018
compound eye developmentGO:004874920.017
response to woundingGO:00096111160.017
nucleoside monophosphate catabolic processGO:000912540.017
regulation of gene expressionGO:00104682650.017
regulation of rna metabolic processGO:00512522240.017
regulation of protein catabolic processGO:004217610.017
membrane invaginationGO:001032410.017
neuron neuron synaptic transmissionGO:000727010.017
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.017
regulation of rna biosynthetic processGO:20011412130.017
positive regulation of protein complex assemblyGO:003133420.017
macromolecule biosynthetic processGO:00090592270.017
striated muscle cell differentiationGO:00511461290.017
protein metabolic processGO:00195381830.017
response to glucocorticoidGO:005138410.017
positive regulation of erk1 and erk2 cascadeGO:007037420.017
aromatic compound biosynthetic processGO:00194382170.017
determination of heart left right asymmetryGO:00613711170.016
cell substrate adhesionGO:003158940.016
lymphangiogenesisGO:0001946250.016
sensory perception of painGO:001923310.016
regulation of nucleotide catabolic processGO:003081120.016
immune responseGO:0006955280.016
carbohydrate derivative metabolic processGO:1901135610.016
neuron differentiationGO:00301823530.016
erk1 and erk2 cascadeGO:007037140.016
single organism biosynthetic processGO:0044711710.016
germ line stem cell maintenanceGO:003071820.016
nucleocytoplasmic transportGO:000691340.016
nucleic acid templated transcriptionGO:00976591810.016
regulation of metabolic processGO:00192223590.016
regulation of gtp catabolic processGO:003312420.015
positive regulation of cellular component biogenesisGO:004408930.015
organic cyclic compound biosynthetic processGO:19013622230.015
negative regulation of epithelial cell proliferationGO:005068010.015
stem cell proliferationGO:007208940.015
negative regulation of apoptotic processGO:0043066550.015
ion transportGO:00068111140.015
regulation of cellular metabolic processGO:00313233200.015
axonogenesisGO:00074091520.015
defense responseGO:0006952470.015
skeletal muscle organ developmentGO:0060538780.015
negative regulation of kinase activityGO:003367340.015
amino acid transportGO:000686520.015
nucleobase containing compound metabolic processGO:00061392740.015
heterocycle biosynthetic processGO:00181302150.015
positive regulation of i kappab kinase nf kappab signalingGO:004312330.015
regulation of cellular biosynthetic processGO:00313262450.015
heart loopingGO:0001947940.015
defense response to bacteriumGO:0042742220.015
epithelial cell differentiationGO:00308551160.014
regulation of erk1 and erk2 cascadeGO:007037240.014
macroautophagyGO:001623610.014
regulation of protein complex assemblyGO:004325430.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.014
gland developmentGO:00487321430.014
forebrain cell migrationGO:002188510.014
regulation of sodium ion transportGO:000202820.014
alpha amino acid metabolic processGO:190160530.014
stem cell divisionGO:001714510.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
heterocycle metabolic processGO:00464832900.014
macromolecule modificationGO:00434121110.014
meiotic cell cycle processGO:190304630.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
positive regulation of map kinase activityGO:004340630.014
negative regulation of signal transductionGO:0009968940.014
regulation of mrna processingGO:005068430.014
hormone secretionGO:004687920.014
response to corticosteroidGO:003196010.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
positive regulation of secretion by cellGO:190353210.014
regulation of primary metabolic processGO:00800903110.014
developmental growth involved in morphogenesisGO:0060560860.014
recombinational repairGO:000072510.014
regulation of dendrite developmentGO:005077330.013
spindle assemblyGO:005122520.013
negative regulation of cell communicationGO:0010648960.013
regulation of nucleoside metabolic processGO:000911820.013
stem cell maintenanceGO:001982740.013
regulation of cell projection assemblyGO:006049140.013
developmental cell growthGO:0048588520.013
positive regulation of epithelial cell migrationGO:001063420.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
cellular response to light stimulusGO:007148240.013
water homeostasisGO:003010440.013
regulation of cytokine productionGO:000181730.013
cellular response to starvationGO:000926710.013
beta amyloid metabolic processGO:005043510.013
tissue remodelingGO:004877140.013
dorsal ventral neural tube patterningGO:002190410.013
cell migrationGO:00164772370.013
response to uvGO:000941130.013
positive regulation of histone modificationGO:003105810.013
positive regulation of nucleotide catabolic processGO:003081310.013
organonitrogen compound biosynthetic processGO:1901566470.013
cortical actin cytoskeleton organizationGO:003086610.013
neuron apoptotic processGO:0051402200.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
cortical cytoskeleton organizationGO:003086510.013
pigmentationGO:0043473850.013
mononuclear cell proliferationGO:003294310.013
muscle tissue developmentGO:00605371100.013
regulation of filopodium assemblyGO:005148920.013
secondary metabolic processGO:001974830.013
enzyme linked receptor protein signaling pathwayGO:00071671060.013
mesenchymal cell differentiationGO:0048762870.012
pigment cell differentiationGO:0050931380.012
response to carbohydrateGO:000974330.012
positive regulation of cellular processGO:00485222010.012
skeletal muscle tissue developmentGO:0007519670.012
positive regulation of dna metabolic processGO:005105410.012
vasculature developmentGO:00019442780.012
angiogenesisGO:00015251580.012
myeloid cell homeostasisGO:0002262560.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
canonical wnt signaling pathwayGO:0060070480.012
ovulation cycle processGO:002260220.012
catechol containing compound metabolic processGO:000971220.012
response to abiotic stimulusGO:00096281220.012
female sex differentiationGO:004666040.012
regulation of dendrite morphogenesisGO:004881430.012
cellular localizationGO:0051641970.012
regulation of protein ubiquitinationGO:003139630.012
muscle organ developmentGO:00075171010.012
calcium ion dependent exocytosisGO:001715610.012
positive regulation of cytoskeleton organizationGO:005149530.012
protein localization to plasma membraneGO:007265910.012
transportGO:00068102200.012
peptidyl lysine acetylationGO:001839420.012
beta amyloid formationGO:003420510.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.012
specification of symmetryGO:00097992040.012
tube closureGO:006060610.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
regulation of cellular component organizationGO:0051128860.012
forebrain developmentGO:0030900960.012
negative regulation of nuclear divisionGO:005178430.012
response to bacteriumGO:0009617580.012
hormone transportGO:000991420.012
primary neural tube formationGO:001402010.012
endothelial cell fate commitmentGO:006083930.012
b cell activationGO:004211320.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
inorganic ion transmembrane transportGO:0098660570.012
regulation of myotube differentiationGO:001083020.012
regulation of ion transmembrane transporter activityGO:003241220.012
single fertilizationGO:000733830.012
regulation of autophagyGO:001050630.012
neural tube developmentGO:0021915620.012
regulation of intracellular protein transportGO:003315730.011
nuclear migrationGO:000709730.011
specification of axis polarityGO:006500140.011
convergent extensionGO:00600261180.011
fat soluble vitamin metabolic processGO:000677540.011
regulation of biosynthetic processGO:00098892500.011
blood vessel morphogenesisGO:00485142160.011
cranial ganglion developmentGO:006155030.011
internal protein amino acid acetylationGO:000647520.011
extracellular matrix organizationGO:0030198270.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
cytokinesisGO:000091030.011
inositol lipid mediated signalingGO:004801720.011
regulation of cell developmentGO:00602841000.011
head developmentGO:00603223030.011
retina development in camera type eyeGO:00600411460.011
behaviorGO:0007610740.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
protein secretionGO:000930610.011
negative regulation of synapse assemblyGO:005196420.011
protein acylationGO:004354330.011
determination of bilateral symmetryGO:00098552040.011
b cell differentiationGO:003018310.011
positive regulation of signal transductionGO:0009967560.011
endocrine processGO:005088620.011
regulation of cellular protein catabolic processGO:190336210.011
muscle cell migrationGO:001481240.011
phosphorus metabolic processGO:00067931090.011
pharyngeal muscle developmentGO:004328240.011
long chain fatty acid metabolic processGO:000167610.011
homeostasis of number of cells within a tissueGO:004887340.011
oocyte anterior posterior axis specificationGO:000731440.011
cellular response to radiationGO:007147840.011
protein dephosphorylationGO:000647030.011
negative regulation of metabolic processGO:0009892860.011
positive regulation of chromosome organizationGO:200125210.011
wound healingGO:0042060900.011
regulation of neurotransmitter transportGO:005158810.011
cell motilityGO:00488702440.011
regulation of transmembrane transporter activityGO:002289820.011
cellular component biogenesisGO:00440851780.011
negative regulation of signalingGO:0023057960.011
appendage developmentGO:0048736800.011
negative regulation of multicellular organismal processGO:0051241690.011
response to external biotic stimulusGO:0043207970.011
regulation of response to cytokine stimulusGO:006075930.011
taxisGO:00423301090.011
regulation of photoreceptor cell differentiationGO:004653220.011
melanocyte differentiationGO:0030318260.011
axis specificationGO:0009798430.010
regulation of anatomical structure morphogenesisGO:00226031300.010
hematopoietic stem cell differentiationGO:0060218200.010
regulation of protein localization to nucleusGO:190018020.010
defense response to other organismGO:0098542330.010
synaptic vesicle localizationGO:009747910.010
catecholamine metabolic processGO:000658420.010
striated muscle tissue developmentGO:00147061100.010
response to vitaminGO:003327330.010
positive regulation of secretionGO:005104710.010
organelle assemblyGO:00709251100.010
apoptotic signaling pathwayGO:0097190230.010
stem cell fate commitmentGO:004886510.010
regulation of protein targetingGO:190353320.010
intracellular signal transductionGO:0035556850.010
regulation of calcium ion transportGO:005192420.010
developmental pigmentationGO:0048066480.010
leukocyte mediated cytotoxicityGO:000190910.010
ameboidal type cell migrationGO:00016671430.010
protein stabilizationGO:005082120.010
embryonic viscerocranium morphogenesisGO:0048703520.010
negative regulation of multi organism processGO:004390130.010
internal peptidyl lysine acetylationGO:001839320.010
positive regulation of cell adhesionGO:004578510.010
multicellular organismal response to stressGO:003355520.010

aph1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.029
muscular diseaseDOID:008000000.025
musculoskeletal system diseaseDOID:1700.025
cardiovascular system diseaseDOID:128700.019
nervous system diseaseDOID:86300.019
disease of metabolismDOID:001466700.016
inherited metabolic disorderDOID:65500.016
myopathyDOID:42300.015
muscle tissue diseaseDOID:6600.015
cancerDOID:16200.015
organ system cancerDOID:005068600.015
disease of cellular proliferationDOID:1456600.015
heart diseaseDOID:11400.011