Danio rerio

0 known processes

mcoln1

mucolipin 1

(Aliases: zgc:63619)

mcoln1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organonitrogen compound metabolic processGO:1901564740.359
organic acid metabolic processGO:0006082310.350
nucleobase containing compound metabolic processGO:00061392740.346
negative regulation of gene expressionGO:0010629650.333
maintenance of locationGO:005123540.328
locomotionGO:00400113130.314
nitrogen compound metabolic processGO:00068073190.298
immune system developmentGO:00025201910.298
regulation of primary metabolic processGO:00800903110.280
nucleic acid metabolic processGO:00903042440.275
carboxylic acid metabolic processGO:0019752220.273
immune system processGO:00023762410.271
regulation of nitrogen compound metabolic processGO:00511712510.267
regulation of biological qualityGO:00650082630.262
response to steroid hormoneGO:0048545350.254
heterocycle metabolic processGO:00464832900.249
inflammatory responseGO:000695480.247
rna biosynthetic processGO:00327741810.244
organic substance biosynthetic processGO:19015762890.237
phagocytosisGO:000690930.235
negative regulation of immune system processGO:000268370.233
regulation of epithelial cell proliferationGO:005067830.226
organic cyclic compound metabolic processGO:19013603010.226
response to chemicalGO:00422213200.221
cellular response to molecule of bacterial originGO:007121930.220
response to fatty acidGO:007054250.219
positive regulation of response to stimulusGO:0048584800.216
brain morphogenesisGO:0048854180.206
nucleobase containing compound biosynthetic processGO:00346542050.197
negative regulation of cellular processGO:00485232830.190
aromatic compound biosynthetic processGO:00194382170.189
transportGO:00068102200.178
cellular aromatic compound metabolic processGO:00067252950.168
hemopoiesisGO:00300971830.167
positive regulation of cellular processGO:00485222010.166
single organism metabolic processGO:00447102170.163
regulation of metabolic processGO:00192223590.163
single organism localizationGO:19025782250.162
head developmentGO:00603223030.162
positive regulation of biological processGO:00485182530.159
phosphate containing compound metabolic processGO:00067961080.152
establishment of localizationGO:00512342440.151
cellular amine metabolic processGO:004410620.151
regulation of inflammatory responseGO:005072720.150
organic substance transportGO:0071702580.149
cellular macromolecule biosynthetic processGO:00346452240.142
oxoacid metabolic processGO:0043436310.141
cellular response to estrogen stimulusGO:0071391240.140
response to vitamin b3GO:003355220.138
cellular nitrogen compound metabolic processGO:00346412900.138
response to lipidGO:0033993600.137
heterocycle biosynthetic processGO:00181302150.130
larval developmentGO:000216420.129
morphogenesis of an epitheliumGO:00020093330.129
cellular response to steroid hormone stimulusGO:0071383310.128
tube morphogenesisGO:00352393490.127
organic cyclic compound biosynthetic processGO:19013622230.127
regulation of nucleic acid templated transcriptionGO:19035062130.126
negative regulation of biological processGO:00485193040.121
organic anion transportGO:0015711150.117
digestive system developmentGO:00551232890.114
macromolecule biosynthetic processGO:00090592270.113
cartilage developmentGO:0051216960.106
response to prostaglandinGO:003469450.104
cell migrationGO:00164772370.104
response to ketoneGO:190165410.100
bmp signaling pathwayGO:0030509520.098
negative regulation of cell deathGO:0060548600.095
negative regulation of cell communicationGO:0010648960.095
digestive tract developmentGO:00485652650.093
regulation of cellular biosynthetic processGO:00313262450.092
regulation of cell deathGO:00109411030.091
regulation of macromolecule biosynthetic processGO:00105562250.091
response to stressGO:00069502630.091
cellular response to hormone stimulusGO:0032870390.089
regulation of transcription dna templatedGO:00063552130.088
central nervous system developmentGO:00074173870.088
response to vitaminGO:003327330.088
hematopoietic or lymphoid organ developmentGO:00485341910.088
cellular response to endogenous stimulusGO:0071495680.087
gland developmentGO:00487321430.087
positive regulation of transportGO:005105020.086
regulation of bmp signaling pathwayGO:0030510390.084
cell motilityGO:00488702440.083
single organism intracellular transportGO:1902582250.082
brain developmentGO:00074202930.082
nuclear importGO:005117030.080
response to estradiolGO:003235560.080
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.079
cell surface receptor signaling pathwayGO:00071663250.078
cellular response to organic cyclic compoundGO:0071407380.077
cellular response to estradiol stimulusGO:007139210.076
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.076
response to nutrientGO:000758430.075
response to organic substanceGO:00100331530.075
myeloid cell differentiationGO:0030099860.073
phosphorus metabolic processGO:00067931090.072
regulation of mitochondrion organizationGO:001082110.070
eye developmentGO:00016542770.070
response to estrogenGO:0043627270.069
negative regulation of nitrogen compound metabolic processGO:0051172590.069
regulation of cellular macromolecule biosynthetic processGO:20001122220.069
regulation of cellular metabolic processGO:00313233200.068
negative regulation of nucleobase containing compound metabolic processGO:0045934590.068
signal transductionGO:00071654550.066
rna metabolic processGO:00160702190.065
gene expressionGO:00104672520.064
cellular response to prostaglandin stimulusGO:007137930.064
regulation of gene expressionGO:00104682650.063
transcription dna templatedGO:00063511810.063
regulation of apoptotic processGO:0042981980.062
nucleic acid templated transcriptionGO:00976591810.062
epithelial tube morphogenesisGO:00605621480.061
cellular response to fatty acidGO:007139830.057
development of primary female sexual characteristicsGO:004654540.056
positive regulation of cellular component biogenesisGO:004408930.056
regulation of defense responseGO:0031347140.055
regulation of programmed cell deathGO:00430671010.054
lateral line system developmentGO:0048925760.053
regulation of cell communicationGO:00106462320.053
single organism transportGO:00447652060.052
regulation of signalingGO:00230512350.052
establishment of protein localization to organelleGO:007259440.051
membrane hyperpolarizationGO:006008110.050
regulation of rna metabolic processGO:00512522240.050
regulation of extrinsic apoptotic signaling pathwayGO:200123630.050
regulation of extent of cell growthGO:0061387290.050
regionalizationGO:00030022740.049
programmed cell deathGO:00125011190.049
embryo development ending in birth or egg hatchingGO:00097922710.048
regulation of nucleobase containing compound metabolic processGO:00192192500.047
establishment of localization in cellGO:0051649770.046
positive regulation of cellular metabolic processGO:0031325940.046
mitochondrion organizationGO:000700540.046
regulation of cellular amine metabolic processGO:003323800.046
response to external stimulusGO:00096052640.046
hepaticobiliary system developmentGO:0061008980.045
erythrocyte homeostasisGO:0034101550.045
liver developmentGO:0001889960.045
regulation of sequestering of calcium ionGO:005128240.045
agingGO:000756820.045
positive regulation of macromolecule biosynthetic processGO:0010557590.044
fin developmentGO:0033333770.044
embryonic organ developmentGO:00485683810.043
intracellular receptor signaling pathwayGO:0030522300.043
connective tissue developmentGO:0061448990.043
calcium ion transportGO:0006816180.042
macromolecular complex subunit organizationGO:0043933740.042
response to acid chemicalGO:0001101170.041
growthGO:00400071740.041
protein targeting to nucleusGO:004474430.040
cellular macromolecule metabolic processGO:00442603910.040
trabecula morphogenesisGO:006138320.040
regulation of jun kinase activityGO:004350630.040
regulation of establishment of planar polarityGO:009017540.040
regulation of rna biosynthetic processGO:20011412130.039
positive regulation of biosynthetic processGO:0009891680.039
positive regulation of secretionGO:005104710.039
negative regulation of response to stimulusGO:00485851040.039
anion transportGO:0006820380.038
guanosine containing compound metabolic processGO:190106840.037
negative regulation of protein kinase activityGO:000646940.037
cell cycleGO:0007049930.037
lipid homeostasisGO:005508830.036
regulation of cellular ketone metabolic processGO:001056570.036
response to endogenous stimulusGO:0009719830.036
negative regulation of bmp signaling pathwayGO:0030514130.036
cellular response to chemical stimulusGO:00708871570.036
negative regulation of macromolecule metabolic processGO:0010605760.035
activation of mapk activityGO:000018730.035
negative regulation of protein phosphorylationGO:000193340.035
system processGO:00030081850.035
deathGO:00162651210.034
positive regulation of secretion by cellGO:190353210.034
regulation of macromolecule metabolic processGO:00602553170.034
somitogenesisGO:0001756870.034
regulation of sterol transportGO:003237130.034
regulation of immune system processGO:0002682340.034
regulation of membrane potentialGO:0042391230.034
response to drugGO:004249330.033
central nervous system myelinationGO:002201020.033
organelle organizationGO:00069962270.033
cellular lipid metabolic processGO:0044255360.033
erythrocyte differentiationGO:0030218540.033
negative regulation of defense responseGO:003134820.033
ectodermal placode formationGO:0060788260.033
behaviorGO:0007610740.032
regulation of biosynthetic processGO:00098892500.032
localization of cellGO:00516742440.032
homeostatic processGO:00425921420.032
lipid storageGO:001991510.031
cellular response to lipidGO:0071396390.031
regulation of hormone secretionGO:004688320.031
regulation of bone remodelingGO:004685020.031
dorsal ventral pattern formationGO:00099531250.030
macromolecule modificationGO:00434121110.030
cellular response to biotic stimulusGO:007121630.030
cellular localizationGO:0051641970.030
retinoic acid receptor signaling pathwayGO:0048384160.029
negative regulation of nuclear divisionGO:005178430.029
positive regulation of map kinase activityGO:004340630.029
nucleoside phosphate metabolic processGO:0006753280.029
regulation of localizationGO:00328791040.029
negative regulation of apoptotic processGO:0043066550.029
cellular biosynthetic processGO:00442492860.029
digestive tract morphogenesisGO:00485462310.029
metal ion transportGO:0030001580.028
chordate embryonic developmentGO:00430092710.028
nitrogen compound transportGO:0071705230.028
response to organic cyclic compoundGO:0014070510.028
protein import into nucleusGO:000660630.028
organophosphate metabolic processGO:0019637370.028
defense responseGO:0006952470.028
cellular response to nutrient levelsGO:003166920.028
regulation of protein modification by small protein conjugation or removalGO:190332030.027
protein importGO:001703830.027
regulation of oxidative stress induced cell deathGO:190320120.027
amine metabolic processGO:000930820.027
macromolecule localizationGO:0033036540.026
regulation of cellular response to oxidative stressGO:190040720.026
cellular response to external stimulusGO:007149620.026
negative regulation of transcription dna templatedGO:0045892450.026
cellular response to stressGO:0033554620.025
regulation of response to stressGO:0080134360.025
sensory system developmentGO:0048880760.025
negative regulation of secretion by cellGO:190353120.025
regulation of cell cycle processGO:0010564200.025
phagocytosis engulfmentGO:000691110.025
negative regulation of metabolic processGO:0009892860.025
positive regulation of catabolic processGO:000989640.025
extrinsic apoptotic signaling pathwayGO:009719130.025
regulation of myeloid cell differentiationGO:004563780.024
response to abiotic stimulusGO:00096281220.024
positive regulation of inflammatory responseGO:005072910.024
regulation of meiotic cell cycleGO:005144510.024
positive regulation of signal transductionGO:0009967560.024
branched chain amino acid metabolic processGO:000908110.024
regulation of cytoplasmic transportGO:190364940.024
regulation of intracellular signal transductionGO:1902531570.024
positive regulation of programmed cell deathGO:0043068290.024
regulation of myeloid leukocyte differentiationGO:000276150.023
cellular protein catabolic processGO:004425740.023
positive regulation of cellular catabolic processGO:003133130.023
mapk cascadeGO:0000165180.023
blood circulationGO:0008015870.023
transmission of nerve impulseGO:0019226190.023
nucleotide metabolic processGO:0009117280.023
protein complex biogenesisGO:0070271300.022
biosynthetic processGO:00090582940.022
positive regulation of gene expressionGO:0010628710.022
cytosolic calcium ion transportGO:006040130.022
positive regulation of signalingGO:0023056560.022
camera type eye developmentGO:00430102220.022
carbohydrate derivative metabolic processGO:1901135610.022
epidermal cell fate specificationGO:000995740.022
regulation of homeostatic processGO:003284490.022
cellular response to oxygen levelsGO:007145310.021
regulation of establishment of protein localizationGO:007020140.021
negative regulation of mitosisGO:004583930.021
protein complex localizationGO:003150310.021
cellular response to extracellular stimulusGO:003166820.021
regulation of cellular amino acid metabolic processGO:000652100.021
regulation of cellular extravasationGO:000269110.021
negative regulation of biosynthetic processGO:0009890550.021
amino acid transportGO:000686520.021
vasculature developmentGO:00019442780.020
appendage morphogenesisGO:0035107560.020
regulation of peptidyl tyrosine phosphorylationGO:005073010.020
positive regulation of lipid metabolic processGO:004583410.020
positive regulation of apoptotic signaling pathwayGO:200123510.020
epithelial cell proliferationGO:0050673170.020
negative regulation of cellular biosynthetic processGO:0031327550.020
cell death in response to oxidative stressGO:003647320.020
otic placode formationGO:0043049230.020
retina morphogenesis in camera type eyeGO:0060042790.020
myeloid cell homeostasisGO:0002262560.020
cellular response to organic substanceGO:00713101050.020
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.020
regulation of multicellular organism growthGO:004001440.020
regulation of protein import into nucleusGO:004230620.019
positive regulation of canonical wnt signaling pathwayGO:009026340.019
tissue remodelingGO:004877140.019
intracellular signal transductionGO:0035556850.019
positive regulation of cell cycleGO:004578730.019
anatomical structure homeostasisGO:0060249360.019
regulation of protein catabolic processGO:004217610.019
female sex differentiationGO:004666040.019
cellular ketone metabolic processGO:0042180110.019
purine ribonucleoside monophosphate catabolic processGO:000916940.018
regulation of phosphorus metabolic processGO:0051174430.018
neural tube patterningGO:0021532330.018
negative regulation of epithelial cell proliferationGO:005068010.018
axon ensheathment in central nervous systemGO:003229120.018
embryonic heart tube developmentGO:00350501330.018
negative regulation of kinase activityGO:003367340.018
negative regulation of cellular metabolic processGO:0031324770.018
positive regulation of cellular biosynthetic processGO:0031328680.018
negative regulation of programmed cell deathGO:0043069580.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.018
small molecule metabolic processGO:0044281770.018
negative regulation of signalingGO:0023057960.018
regulation of calcium ion transportGO:005192420.018
organelle fusionGO:004828430.018
cellular component movementGO:00069283350.017
glycerolipid metabolic processGO:004648670.017
regulation of cell activationGO:005086510.017
type b pancreatic cell proliferationGO:004434210.017
ameboidal type cell migrationGO:00016671430.017
epithelial tube formationGO:0072175190.017
tissue homeostasisGO:0001894250.017
regulation of tissue remodelingGO:003410320.017
establishment of mitotic spindle localizationGO:0040001120.017
ovulation cycle processGO:002260220.017
cell agingGO:000756920.017
fatty acid metabolic processGO:000663150.017
mesoderm developmentGO:0007498880.017
generation of neuronsGO:00486993850.017
transcription from rna polymerase ii promoterGO:0006366800.017
mitotic nuclear divisionGO:0007067180.016
innate immune responseGO:0045087130.016
signal transduction by phosphorylationGO:0023014180.016
granulocyte migrationGO:0097530110.016
positive regulation of nucleotide catabolic processGO:003081310.016
organic hydroxy compound transportGO:0015850140.016
neurological system processGO:0050877620.016
glycerolipid biosynthetic processGO:004501710.016
positive regulation of bmp signaling pathwayGO:0030513100.016
proteolysisGO:0006508380.016
regulation of developmental processGO:00507932470.016
endocytosisGO:0006897160.015
determination of dorsal ventral asymmetryGO:0048262340.015
otic vesicle developmentGO:0071599420.015
negative regulation of rna metabolic processGO:0051253480.015
nucleoside monophosphate catabolic processGO:000912540.015
enzyme linked receptor protein signaling pathwayGO:00071671060.015
cellular respirationGO:004533330.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
multicellular organismal metabolic processGO:004423620.015
cell deathGO:00082191210.015
single organism nuclear importGO:190259330.014
cell fate commitmentGO:0045165990.014
regulation of cellular component organizationGO:0051128860.014
modification dependent protein catabolic processGO:001994130.014
positive regulation of nucleobase containing compound metabolic processGO:0045935690.014
regulation of phosphate metabolic processGO:0019220430.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
peptide transportGO:001583310.014
urogenital system developmentGO:0001655970.014
non canonical wnt signaling pathwayGO:0035567130.014
regulation of catalytic activityGO:0050790550.014
negative regulation of hormone secretionGO:004688820.014
protein metabolic processGO:00195381830.014
endoderm developmentGO:0007492490.014
regulation of protein targetingGO:190353320.014
female gonad developmentGO:000858540.014
blood vessel developmentGO:00015682460.014
protein localizationGO:0008104400.014
b cell activationGO:004211320.014
regulation of signal transductionGO:00099662250.013
somite developmentGO:0061053960.013
wnt signaling pathway planar cell polarity pathwayGO:006007140.013
regulation of mitosisGO:000708890.013
cellular response to lipopolysaccharideGO:007122230.013
regulation of protein complex assemblyGO:004325430.013
meiotic nuclear divisionGO:000712640.013
defense response to fungusGO:005083220.013
secondary metabolic processGO:001974830.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
cell proliferationGO:0008283800.013
ribonucleotide metabolic processGO:0009259270.013
cellular amino acid metabolic processGO:000652070.013
regulation of metal ion transportGO:001095940.013
ion transportGO:00068111140.013
mitotic cell cycle processGO:1903047480.013
single organism biosynthetic processGO:0044711710.013
regulation of mapk cascadeGO:0043408140.013
regulation of response to stimulusGO:00485832690.013
regulation of lipid transportGO:003236840.012
organonitrogen compound biosynthetic processGO:1901566470.012
regulation of response to oxidative stressGO:190288220.012
circulatory system processGO:0003013870.012
gtp catabolic processGO:000618420.012
regulation of nucleocytoplasmic transportGO:004682220.012
regulation of dna replicationGO:000627530.012
segmentationGO:0035282970.012
regulation of response to woundingGO:1903034110.012
leukocyte homeostasisGO:000177620.012
negative regulation of mapk cascadeGO:004340940.012
metal ion homeostasisGO:0055065260.012
cation homeostasisGO:0055080330.012
regulation of chronic inflammatory responseGO:000267610.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
apoptotic processGO:00069151160.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.012
skeletal system developmentGO:00015011810.012
regulation of endocytosisGO:003010070.012
specification of axis polarityGO:006500140.012
blood vessel morphogenesisGO:00485142160.012
response to ionizing radiationGO:001021260.012
sequestering of calcium ionGO:005120830.012
neuron neuron synaptic transmissionGO:000727010.012
regulation of intracellular protein transportGO:003315730.012
response to glucocorticoidGO:005138410.012
negative regulation of leukocyte differentiationGO:190210610.012
leukocyte differentiationGO:0002521250.011
regulation of wound healingGO:006104120.011
response to hexoseGO:000974630.011
lipid metabolic processGO:0006629520.011
endosomal transportGO:001619720.011
nucleocytoplasmic transportGO:000691340.011
specification of symmetryGO:00097992040.011
myeloid cell developmentGO:0061515320.011
regulation of cell differentiationGO:00455951420.011
hormone secretionGO:004687920.011
positive regulation of translationGO:004572710.011
camera type eye morphogenesisGO:00485931080.011
cellular response to radiationGO:007147840.011
negative regulation of signal transductionGO:0009968940.011
cellular nitrogen compound biosynthetic processGO:00442712180.011
response to alkaloidGO:004327920.011
response to corticosteroidGO:003196010.011
primary neural tube formationGO:001402010.011
mitochondrial transportGO:000683920.011
actin filament polymerizationGO:003004120.011
positive regulation of cell deathGO:0010942290.011
regulation of nervous system developmentGO:0051960900.011
purine ribonucleotide metabolic processGO:0009150270.011
chemotaxisGO:00069351040.011
cell cycle processGO:0022402530.011
appendage developmentGO:0048736800.011
positive regulation of cytokine productionGO:000181920.011
protein phosphorylationGO:0006468470.011
regulation of molecular functionGO:0065009700.011
apoptotic signaling pathwayGO:0097190230.011
homeostasis of number of cellsGO:0048872620.010
positive regulation of epithelial cell proliferationGO:005067910.010
negative regulation of secretionGO:005104820.010
wnt signaling pathwayGO:0016055800.010
response to external biotic stimulusGO:0043207970.010
protein localization to nucleusGO:003450430.010
convergent extension involved in gastrulationGO:0060027710.010
adult behaviorGO:003053420.010
endocrine system developmentGO:0035270650.010
gland morphogenesisGO:0022612130.010
response to hormoneGO:0009725480.010

mcoln1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.073
disease of metabolismDOID:001466700.073
lysosomal storage diseaseDOID:321100.073
nervous system diseaseDOID:86300.040
disease of anatomical entityDOID:700.040
lipid storage diseaseDOID:945500.019
central nervous system diseaseDOID:33100.010