Danio rerio

0 known processes

spop

speckle-type POZ protein

(Aliases: zgc:64140,MGC64140,MGC174052)

spop biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of biosynthetic processGO:00098892500.072
Mouse
regionalizationGO:00030022740.057
cellular component movementGO:00069283350.055
regulation of gene expressionGO:00104682650.055
Mouse
nucleic acid metabolic processGO:00903042440.055
Mouse
cellular aromatic compound metabolic processGO:00067252950.054
Mouse
maintenance of locationGO:005123540.050
regulation of macromolecule metabolic processGO:00602553170.050
Mouse
regulation of metabolic processGO:00192223590.049
Mouse
signal transductionGO:00071654550.049
Mouse
nitrogen compound metabolic processGO:00068073190.048
Mouse
cellular macromolecule metabolic processGO:00442603910.048
Human Mouse
proteolysis involved in cellular protein catabolic processGO:005160330.048
Human Mouse
multicellular organism growthGO:003526440.048
cellular biosynthetic processGO:00442492860.047
Mouse
regulation of multicellular organism growthGO:004001440.046
modification dependent protein catabolic processGO:001994130.046
Human Mouse
localization of cellGO:00516742440.045
regulation of macromolecule biosynthetic processGO:00105562250.045
Mouse
positive regulation of transportGO:005105020.045
morphogenesis of an epitheliumGO:00020093330.044
regulation of cytokine productionGO:000181730.044
heterocycle metabolic processGO:00464832900.044
Mouse
ubiquitin dependent protein catabolic processGO:000651130.043
Human Mouse
cellular nitrogen compound biosynthetic processGO:00442712180.043
Mouse
cell morphogenesisGO:00009022890.043
organic cyclic compound biosynthetic processGO:19013622230.042
Mouse
heterocycle biosynthetic processGO:00181302150.042
Mouse
regulation of establishment of protein localizationGO:007020140.042
phagocytosisGO:000690930.042
cellular nitrogen compound metabolic processGO:00346412900.042
Mouse
nucleobase containing compound metabolic processGO:00061392740.041
Mouse
negative regulation of biological processGO:00485193040.040
Mouse
larval developmentGO:000216420.039
response to stressGO:00069502630.039
Mouse
protein import into nucleusGO:000660630.039
cognitionGO:005089010.038
establishment of protein localization to organelleGO:007259440.038
lipid storageGO:001991510.038
gene expressionGO:00104672520.038
Mouse
regulation of cellular biosynthetic processGO:00313262450.037
Mouse
rna metabolic processGO:00160702190.037
Mouse
organic substance biosynthetic processGO:19015762890.037
Mouse
cell projection morphogenesisGO:00488582440.036
nuclear transportGO:005116940.036
tube morphogenesisGO:00352393490.036
cell motilityGO:00488702440.036
macromolecule biosynthetic processGO:00090592270.036
Mouse
blood vessel developmentGO:00015682460.036
nucleobase containing compound biosynthetic processGO:00346542050.036
Mouse
cell migrationGO:00164772370.036
heart developmentGO:00075073130.036
hematopoietic or lymphoid organ developmentGO:00485341910.035
response to chemicalGO:00422213200.035
regulation of cellular macromolecule biosynthetic processGO:20001122220.035
Mouse
response to external stimulusGO:00096052640.035
rna biosynthetic processGO:00327741810.034
Mouse
positive regulation of biological processGO:00485182530.034
Mouse
hemopoiesisGO:00300971830.034
cell projection organizationGO:00300302840.034
regulation of multicellular organismal processGO:00512392770.034
nucleic acid templated transcriptionGO:00976591810.033
Mouse
sensory organ developmentGO:00074233930.033
organic cyclic compound metabolic processGO:19013603010.033
Mouse
nucleocytoplasmic transportGO:000691340.033
cellular component morphogenesisGO:00329893360.033
cellular macromolecule biosynthetic processGO:00346452240.033
Mouse
negative regulation of cellular processGO:00485232830.032
Mouse
digestive tract developmentGO:00485652650.032
agingGO:000756820.032
single organism nuclear importGO:190259330.031
regulation of cellular metabolic processGO:00313233200.031
Mouse
digestive system developmentGO:00551232890.031
modification dependent macromolecule catabolic processGO:004363230.031
Human Mouse
cell part morphogenesisGO:00329902460.030
generation of neuronsGO:00486993850.030
erk1 and erk2 cascadeGO:007037140.030
regulation of developmental processGO:00507932470.030
cell surface receptor signaling pathwayGO:00071663250.030
immune system developmentGO:00025201910.030
regulation of protein transportGO:005122330.030
protein importGO:001703830.029
developmental growthGO:00485891660.029
cellular response to external stimulusGO:007149620.029
aromatic compound biosynthetic processGO:00194382170.029
Mouse
extrinsic apoptotic signaling pathwayGO:009719130.029
regulation of rna biosynthetic processGO:20011412130.029
Mouse
embryonic organ developmentGO:00485683810.029
positive regulation of cytokine productionGO:000181920.028
regulation of biological qualityGO:00650082630.028
Mouse
mitochondrion organizationGO:000700540.028
negative regulation of mitosisGO:004583930.028
growthGO:00400071740.028
neuron differentiationGO:00301823530.028
regulation of nucleobase containing compound metabolic processGO:00192192500.028
Mouse
protein localization to nucleusGO:003450430.028
biosynthetic processGO:00090582940.028
Mouse
gastrulationGO:00073692080.028
homeostatic processGO:00425921420.027
Mouse
cellular protein catabolic processGO:004425740.027
Human Mouse
immune system processGO:00023762410.027
nuclear importGO:005117030.027
central nervous system developmentGO:00074173870.027
cellular amine metabolic processGO:004410620.027
regulation of primary metabolic processGO:00800903110.027
Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.027
Mouse
protein secretionGO:000930610.026
convergent extensionGO:00600261180.026
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
Human Mouse
regulation of cytoplasmic transportGO:190364940.026
establishment of localizationGO:00512342440.026
positive regulation of cell activationGO:005086710.025
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.025
amine metabolic processGO:000930820.025
regulation of rna metabolic processGO:00512522240.025
Mouse
transcription dna templatedGO:00063511810.025
Mouse
locomotionGO:00400113130.025
regulation of erk1 and erk2 cascadeGO:007037240.025
cellular response to extracellular stimulusGO:003166820.025
leukocyte proliferationGO:007066110.024
oxoacid metabolic processGO:0043436310.024
regulation of cellular amino acid metabolic processGO:000652100.024
regulation of cellular amine metabolic processGO:003323800.024
negative regulation of protein phosphorylationGO:000193340.024
neuron developmentGO:00486662620.024
cellular amino acid metabolic processGO:000652070.024
regulation of signal transductionGO:00099662250.024
Mouse
tissue remodelingGO:004877140.023
vasculature developmentGO:00019442780.023
negative regulation of nuclear divisionGO:005178430.023
embryonic organ morphogenesisGO:00485622740.023
peptidyl serine phosphorylationGO:001810510.023
positive regulation of erk1 and erk2 cascadeGO:007037420.023
sequestering of calcium ionGO:005120830.023
organic acid metabolic processGO:0006082310.023
protein metabolic processGO:00195381830.023
Human Mouse
carboxylic acid metabolic processGO:0019752220.023
cilium morphogenesisGO:0060271850.023
proteasomal protein catabolic processGO:001049820.023
Human Mouse
membrane invaginationGO:001032410.023
calcium ion transport into cytosolGO:006040230.023
regulation of cellular ketone metabolic processGO:001056570.023
regulation of bindingGO:005109830.023
cellular response to nutrient levelsGO:003166920.023
deathGO:00162651210.023
Mouse
regulation of protein targetingGO:190353320.023
chordate embryonic developmentGO:00430092710.023
protein targeting to nucleusGO:004474430.023
regulation of nitrogen compound metabolic processGO:00511712510.022
Mouse
regulation of protein import into nucleusGO:004230620.022
regulation of nucleocytoplasmic transportGO:004682220.022
peptidyl serine modificationGO:001820920.022
regulation of cell activationGO:005086510.022
ameboidal type cell migrationGO:00016671430.022
regulation of response to stimulusGO:00485832690.022
Mouse
regulation of intracellular protein transportGO:003315730.022
single organism metabolic processGO:00447102170.021
determination of bilateral symmetryGO:00098552040.021
anterior posterior pattern specificationGO:00099521520.021
sequestering of metal ionGO:005123830.021
regulation of sequestering of calcium ionGO:005128240.021
cellular response to chemical stimulusGO:00708871570.021
negative regulation of sequestering of calcium ionGO:005128340.021
response to drugGO:004249330.021
positive regulation of stress activated mapk cascadeGO:003287430.021
cellular response to biotic stimulusGO:007121630.021
negative regulation of catabolic processGO:000989530.021
single organism transportGO:00447652060.021
camera type eye developmentGO:00430102220.021
meiotic nuclear divisionGO:000712640.021
regulation of cell communicationGO:00106462320.021
Mouse
stem cell maintenanceGO:001982740.020
cellular component assemblyGO:00226071700.020
neuron projection morphogenesisGO:00488121610.020
neuron projection developmentGO:00311751800.020
cellular ketone metabolic processGO:0042180110.020
positive regulation of small gtpase mediated signal transductionGO:005105710.020
positive regulation of cytosolic calcium ion concentrationGO:000720440.020
digestive tract morphogenesisGO:00485462310.020
blood vessel morphogenesisGO:00485142160.020
single organism organelle organizationGO:19025891990.020
positive regulation of cell adhesionGO:004578510.020
regulation of multicellular organismal developmentGO:20000262230.020
adult behaviorGO:003053420.020
specification of symmetryGO:00097992040.020
embryo development ending in birth or egg hatchingGO:00097922710.019
negative regulation of signal transductionGO:0009968940.019
developmental growth involved in morphogenesisGO:0060560860.019
protein polyubiquitinationGO:000020940.019
peptidyl lysine acetylationGO:001839420.019
eye developmentGO:00016542770.019
regulation of meiotic cell cycleGO:005144510.019
gtp catabolic processGO:000618420.019
regulation of cell differentiationGO:00455951420.019
protein acylationGO:004354330.019
cellular component biogenesisGO:00440851780.019
protein acetylationGO:000647320.019
determination of left right symmetryGO:00073681790.019
axonogenesisGO:00074091520.019
organonitrogen compound metabolic processGO:1901564740.019
angiogenesisGO:00015251580.019
small molecule metabolic processGO:0044281770.018
intracellular signal transductionGO:0035556850.018
Mouse
cell substrate adhesionGO:003158940.018
regulation of transcription dna templatedGO:00063552130.018
Mouse
somite developmentGO:0061053960.018
fertilizationGO:000956630.018
positive regulation of nitrogen compound metabolic processGO:0051173690.018
positive regulation of immune effector processGO:000269930.018
stem cell proliferationGO:007208940.018
internal protein amino acid acetylationGO:000647520.018
regulation of signalingGO:00230512350.018
Mouse
organelle fusionGO:004828430.018
single organism membrane fusionGO:004480120.018
cellular protein metabolic processGO:00442671290.018
Human Mouse
positive regulation of cellular component biogenesisGO:004408930.018
internal peptidyl lysine acetylationGO:001839320.018
regulation of mrna splicing via spliceosomeGO:004802430.018
regulation of protein catabolic processGO:004217610.018
cellular protein modification processGO:00064641000.018
Mouse
positive regulation of cellular processGO:00485222010.018
Mouse
response to nutrientGO:000758430.018
positive regulation of cell cycleGO:004578730.018
single organism localizationGO:19025782250.018
regulation of protein localization to nucleusGO:190018020.017
cellular response to starvationGO:000926710.017
segmentationGO:0035282970.017
mesenchyme developmentGO:00604851270.017
dorsal ventral pattern formationGO:00099531250.017
cytokinesisGO:000091030.017
positive regulation of catabolic processGO:000989640.017
mesenchymal cell differentiationGO:0048762870.017
phagocytosis engulfmentGO:000691110.017
g1 s transition of mitotic cell cycleGO:000008210.017
negative regulation of response to stimulusGO:00485851040.017
protein localization to plasma membraneGO:007265910.017
head developmentGO:00603223030.017
positive regulation of secretionGO:005104710.017
compound eye developmentGO:004874920.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
regulation of nucleotide catabolic processGO:003081120.016
transcription from rna polymerase ii promoterGO:0006366800.016
Mouse
brain developmentGO:00074202930.016
negative regulation of cellular catabolic processGO:003133030.016
locomotor rhythmGO:004547530.016
cytosolic calcium ion transportGO:006040130.016
response to bacteriumGO:0009617580.016
release of sequestered calcium ion into cytosolGO:005120930.016
gtp metabolic processGO:004603940.016
regulation of cell deathGO:00109411030.016
Mouse
negative regulation of multicellular organismal processGO:0051241690.016
atp catabolic processGO:000620040.016
multi organism processGO:00517041340.016
negative regulation of protein kinase activityGO:000646940.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
cell deathGO:00082191210.016
Mouse
macroautophagyGO:001623610.016
guanosine containing compound catabolic processGO:190106920.016
positive regulation of canonical wnt signaling pathwayGO:009026340.016
regulation of synaptic plasticityGO:004816710.016
positive regulation of cytoskeleton organizationGO:005149530.016
regulation of extrinsic apoptotic signaling pathwayGO:200123630.016
purine ribonucleoside monophosphate catabolic processGO:000916940.016
myeloid cell differentiationGO:0030099860.016
epithelial tube morphogenesisGO:00605621480.016
negative regulation of kinase activityGO:003367340.015
purine nucleoside monophosphate catabolic processGO:000912840.015
exocytosisGO:000688710.015
positive regulation of secretion by cellGO:190353210.015
endosomal transportGO:001619720.015
regulation of reproductive processGO:200024140.015
negative regulation of signalingGO:0023057960.015
macromolecule modificationGO:00434121110.015
Mouse
positive regulation of cellular catabolic processGO:003133130.015
protein stabilizationGO:005082120.015
axon developmentGO:00615641660.015
autophagyGO:000691440.015
cell morphogenesis involved in neuron differentiationGO:00486671630.015
regulation of cell shapeGO:000836010.015
tissue regenerationGO:0042246740.015
cellular component disassemblyGO:002241110.015
regulation of purine nucleotide catabolic processGO:003312120.015
meiotic cell cycle processGO:190304630.015
enzyme linked receptor protein signaling pathwayGO:00071671060.015
regulation of protein modification by small protein conjugation or removalGO:190332030.015
cellular response to organic substanceGO:00713101050.015
organelle organizationGO:00069962270.015
muscle structure developmentGO:00610611960.015
positive regulation of i kappab kinase nf kappab signalingGO:004312330.015
regenerationGO:0031099910.015
positive regulation of response to stimulusGO:0048584800.015
Mouse
regulation of stem cell differentiationGO:200073640.015
wnt signaling pathwayGO:0016055800.015
regulation of gtp catabolic processGO:003312420.015
cellular amide metabolic processGO:004360340.015
transportGO:00068102200.015
guanosine containing compound metabolic processGO:190106840.015
skeletal system morphogenesisGO:00487051020.015
negative regulation of mapk cascadeGO:004340940.014
cellular response to lipopolysaccharideGO:007122230.014
sensory organ morphogenesisGO:00905962000.014
ribonucleoside monophosphate catabolic processGO:000915840.014
activation of mapk activityGO:000018730.014
cellular response to endogenous stimulusGO:0071495680.014
stem cell developmentGO:0048864820.014
response to biotic stimulusGO:0009607970.014
interspecies interaction between organismsGO:004441940.014
cilium organizationGO:0044782710.014
mononuclear cell proliferationGO:003294310.014
membrane fusionGO:006102520.014
stem cell differentiationGO:00488631170.014
regulation of metal ion transportGO:001095940.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
phosphate containing compound metabolic processGO:00067961080.014
system processGO:00030081850.014
chemotaxisGO:00069351040.014
somitogenesisGO:0001756870.014
mitochondrial transportGO:000683920.014
female meiotic divisionGO:000714320.014
cell cycle g1 s phase transitionGO:004484310.014
macromolecular complex disassemblyGO:003298410.014
regulation of cell developmentGO:00602841000.014
taxisGO:00423301090.014
synaptic growth at neuromuscular junctionGO:005112420.014
adherens junction organizationGO:003433240.014
response to glucoseGO:000974930.014
positive regulation of cellular amine metabolic processGO:003324000.014
chemosensory behaviorGO:000763510.014
response to other organismGO:0051707970.013
mitotic dna damage checkpointGO:004477340.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
response to carbohydrateGO:000974330.013
protein modification processGO:00362111000.013
Mouse
female sex differentiationGO:004666040.013
nucleoside monophosphate catabolic processGO:000912540.013
response to monosaccharideGO:003428430.013
epithelial cell differentiationGO:00308551160.013
regulation of programmed cell deathGO:00430671010.013
Mouse
negative regulation of secretionGO:005104820.013
cellular localizationGO:0051641970.013
negative regulation of cell communicationGO:0010648960.013
regulation of circadian rhythmGO:004275240.013
positive regulation of protein complex assemblyGO:003133420.013
regulation of neural precursor cell proliferationGO:200017730.013
germ line stem cell maintenanceGO:003071820.013
urogenital system developmentGO:0001655970.013
mesenchymal cell developmentGO:0014031780.013
regulation of protein ubiquitinationGO:003139630.013
regulation of response to biotic stimulusGO:000283120.013
neuroblast proliferationGO:000740520.013
eye morphogenesisGO:00485921440.013
peptide transportGO:001583310.013
development of primary female sexual characteristicsGO:004654540.013
ear developmentGO:00435831270.013
negative regulation of wnt signaling pathwayGO:0030178300.013
cellular carbohydrate metabolic processGO:004426240.013
double strand break repairGO:000630230.013
gland developmentGO:00487321430.013
single fertilizationGO:000733830.013
regulation of nucleoside metabolic processGO:000911820.013
cartilage developmentGO:0051216960.013
response to hexoseGO:000974630.013
cell proliferationGO:0008283800.013
regulation of transcription from rna polymerase ii promoterGO:00063571140.013
Mouse
positive regulation of translationGO:004572710.013
embryonic skeletal system developmentGO:0048706970.013
cell morphogenesis involved in differentiationGO:00009041950.013
protein homooligomerizationGO:005126030.013
response to woundingGO:00096111160.012
cellular respirationGO:004533330.012
somatic stem cell maintenanceGO:003501910.012
skeletal system developmentGO:00015011810.012
response to endogenous stimulusGO:0009719830.012
gastrulation with mouth forming secondGO:0001702440.012
inner ear developmentGO:00488391260.012
regulation of cellular protein catabolic processGO:190336210.012
regulation of protein bindingGO:004339330.012
wound healingGO:0042060900.012
regulation of anatomical structure morphogenesisGO:00226031300.012
cilium assemblyGO:0042384580.012
mitotic dna integrity checkpointGO:004477440.012
positive regulation of ras protein signal transductionGO:004657910.012
synaptic vesicle localizationGO:009747910.012
i kappab kinase nf kappab signalingGO:000724940.012
organic acid catabolic processGO:001605430.012
translational initiationGO:000641330.012
phosphorus metabolic processGO:00067931090.012
regulation of mrna processingGO:005068430.012
renal system developmentGO:0072001940.012
b cell activationGO:004211320.012
negative regulation of cytokine productionGO:000181810.012
neurotransmitter transportGO:000683620.012
negative regulation of defense responseGO:003134820.012
regulation of inflammatory responseGO:005072720.012
periodic partitioningGO:000736510.012
establishment of synaptic vesicle localizationGO:009748010.012
regulation of tube sizeGO:003515020.012
regulation of synapse organizationGO:005080730.012
regulation of jak stat cascadeGO:004642530.012
negative regulation of protein transportGO:005122430.012
regulation of epithelial cell proliferationGO:005067830.012
protein complex disassemblyGO:004324110.012
positive regulation of dna metabolic processGO:005105410.012
regulation of canonical wnt signaling pathwayGO:0060828340.012
regulation of alternative mrna splicing via spliceosomeGO:000038110.012
regulation of gtpase activityGO:004308720.012
fin regenerationGO:0031101510.012
regulation of cell substrate adhesionGO:001081010.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
pancreas developmentGO:0031016840.012
ras protein signal transductionGO:000726570.012
lymphocyte proliferationGO:004665110.012
liver developmentGO:0001889960.012
mesoderm developmentGO:0007498880.012
response to organic substanceGO:00100331530.011
muscle tissue developmentGO:00605371100.011
spermatid differentiationGO:004851520.011
cytoskeleton dependent cytokinesisGO:006164030.011
regulation of rho protein signal transductionGO:003502320.011
mitotic g2 m transition checkpointGO:004481830.011
negative regulation of metabolic processGO:0009892860.011
Mouse
multi organism cellular processGO:004476420.011
positive regulation of leukocyte differentiationGO:190210710.011
positive regulation of signal transductionGO:0009967560.011
Mouse
regulation of production of molecular mediator of immune responseGO:000270010.011
synaptic vesicle transportGO:004848910.011
cellular response to radiationGO:007147840.011
regulation of locomotionGO:0040012550.011
response to external biotic stimulusGO:0043207970.011
protein dephosphorylationGO:000647030.011
regulation of calcium ion transportGO:005192420.011
negative regulation of cellular metabolic processGO:0031324770.011
Mouse
negative regulation of macromolecule metabolic processGO:0010605760.011
Mouse
neurotransmitter secretionGO:000726920.011
developmental programmed cell deathGO:001062340.011
small gtpase mediated signal transductionGO:000726480.011
negative regulation of developmental processGO:0051093650.011
positive regulation of jnk cascadeGO:004633030.011
somatic muscle developmentGO:000752540.011
tube closureGO:006060610.011
positive regulation of cellular biosynthetic processGO:0031328680.011
cell migration involved in gastrulationGO:0042074790.011
g2 dna damage checkpointGO:003157230.011
erythrocyte differentiationGO:0030218540.011
programmed cell deathGO:00125011190.011
Mouse
regulation of cellular component organizationGO:0051128860.011
muscle organ developmentGO:00075171010.011
connective tissue developmentGO:0061448990.011
regulation of wnt signaling pathwayGO:0030111530.011
embryonic skeletal system morphogenesisGO:0048704930.011
female gonad developmentGO:000858540.011
mitotic cytokinesisGO:000028130.011
antimicrobial humoral responseGO:001973020.011
positive regulation of biosynthetic processGO:0009891680.011
retina development in camera type eyeGO:00600411460.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
Mouse
forebrain developmentGO:0030900960.011
viral processGO:001603210.011
positive regulation of macromolecule metabolic processGO:0010604930.010
rna localizationGO:000640340.010
regulation of cell migrationGO:0030334400.010
cellular response to molecule of bacterial originGO:007121930.010
positive regulation of nucleoside metabolic processGO:004597910.010
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.010
Mouse
hormone secretionGO:004687920.010
erythrocyte homeostasisGO:0034101550.010
negative regulation of biosynthetic processGO:0009890550.010
Mouse
spermatid developmentGO:000728620.010
regulation of apoptotic processGO:0042981980.010
Mouse
negative regulation of multi organism processGO:004390130.010
carbohydrate homeostasisGO:003350010.010
Mouse
regulation of cell motilityGO:2000145460.010

spop disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.022
disease of metabolismDOID:001466700.016
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
sensory system diseaseDOID:005015500.013
organ system cancerDOID:005068600.012
inherited metabolic disorderDOID:65500.011
eye and adnexa diseaseDOID:149200.010