Danio rerio

34 known processes

otx1a

orthodenticle homolog 1a

(Aliases: otx1l,otx3)

otx1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of anatomical structure morphogenesisGO:00226031300.977
Zebrafish Fly
sensory organ developmentGO:00074233930.969
neuron differentiationGO:00301823530.964
Zebrafish Worm Fly
cellular component morphogenesisGO:00329893360.928
Fly
signal transductionGO:00071654550.919
generation of neuronsGO:00486993850.914
Zebrafish Worm Fly
nucleic acid templated transcriptionGO:00976591810.895
Human Zebrafish Mouse Worm Fly
embryonic organ morphogenesisGO:00485622740.832
Mouse
cell morphogenesis involved in differentiationGO:00009041950.829
Fly
negative regulation of cellular processGO:00485232830.808
Zebrafish Fly
neuron projection developmentGO:00311751800.805
Fly
neuron projection morphogenesisGO:00488121610.788
Fly
heterocycle metabolic processGO:00464832900.781
Human Zebrafish Mouse Worm Fly
transcription dna templatedGO:00063511810.777
Human Zebrafish Mouse Worm Fly
cell morphogenesis involved in neuron differentiationGO:00486671630.761
Fly
regulation of nucleic acid templated transcriptionGO:19035062130.758
Human Zebrafish Mouse Worm Fly
neuron developmentGO:00486662620.740
Zebrafish Fly
regulation of macromolecule biosynthetic processGO:00105562250.710
Human Zebrafish Mouse Worm Fly
camera type eye developmentGO:00430102220.690
regulation of collateral sprouting of intact axon in response to injuryGO:004868320.676
cell morphogenesisGO:00009022890.645
Fly
negative regulation of collateral sprouting of intact axon in response to injuryGO:004868520.628
central nervous system developmentGO:00074173870.626
eye developmentGO:00016542770.622
rna metabolic processGO:00160702190.609
Human Zebrafish Mouse Worm Fly
embryonic organ developmentGO:00485683810.608
Mouse
cell surface receptor signaling pathwayGO:00071663250.605
axonogenesisGO:00074091520.601
gene expressionGO:00104672520.584
Human Zebrafish Mouse Worm Fly
regulation of primary metabolic processGO:00800903110.584
Human Zebrafish Mouse Worm Fly
head developmentGO:00603223030.528
rna biosynthetic processGO:00327741810.496
Human Zebrafish Mouse Worm Fly
axon guidanceGO:0007411860.495
cellular aromatic compound metabolic processGO:00067252950.450
Human Zebrafish Mouse Worm Fly
axon developmentGO:00615641660.448
aromatic compound biosynthetic processGO:00194382170.445
Human Zebrafish Mouse Worm Fly
cellular component movementGO:00069283350.445
organic cyclic compound metabolic processGO:19013603010.442
Human Zebrafish Mouse Worm Fly
cell migrationGO:00164772370.429
cellular macromolecule metabolic processGO:00442603910.428
Human Zebrafish Mouse Worm Fly
gliogenesisGO:0042063450.427
nucleic acid metabolic processGO:00903042440.426
Human Zebrafish Mouse Worm Fly
regulation of nervous system developmentGO:0051960900.425
Fly
heterocycle biosynthetic processGO:00181302150.403
Human Zebrafish Mouse Worm Fly
digestive tract morphogenesisGO:00485462310.392
endoderm developmentGO:0007492490.383
cellular macromolecule biosynthetic processGO:00346452240.380
Human Zebrafish Mouse Worm Fly
specification of symmetryGO:00097992040.377
regulation of gene expressionGO:00104682650.375
Human Zebrafish Mouse Worm Fly
nucleobase containing compound biosynthetic processGO:00346542050.363
Human Zebrafish Mouse Worm Fly
regulation of multicellular organismal developmentGO:20000262230.355
Zebrafish Fly
regulation of reproductive processGO:200024140.351
negative regulation of neuron projection regenerationGO:007057140.351
hindbrain developmentGO:0030902910.349
negative regulation of collateral sproutingGO:004867120.346
retina development in camera type eyeGO:00600411460.340
oligodendrocyte differentiationGO:0048709230.338
cell fate commitmentGO:0045165990.330
Worm Fly
diencephalon developmentGO:0021536580.325
Mouse
organic cyclic compound biosynthetic processGO:19013622230.324
Human Zebrafish Mouse Worm Fly
angioblast cell migration involved in selective angioblast sproutingGO:003547540.321
tube morphogenesisGO:00352393490.315
thalamus developmentGO:002179460.313
response to chemicalGO:00422213200.301
Zebrafish Worm
peripheral nervous system developmentGO:0007422550.291
glial cell fate specificationGO:002178040.287
regulation of nitrogen compound metabolic processGO:00511712510.279
Human Zebrafish Mouse Worm Fly
cellular biosynthetic processGO:00442492860.277
Human Zebrafish Mouse Worm Fly
cell projection morphogenesisGO:00488582440.276
Fly
convergent extensionGO:00600261180.274
cellular nitrogen compound metabolic processGO:00346412900.271
Human Zebrafish Mouse Worm Fly
eye morphogenesisGO:00485921440.270
Zebrafish Fly
chordate embryonic developmentGO:00430092710.270
system processGO:00030081850.267
Zebrafish Worm
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.267
Fly
digestive system developmentGO:00551232890.266
retinal ganglion cell axon guidanceGO:0031290350.266
ectodermal placode formationGO:0060788260.260
determination of heart left right asymmetryGO:00613711170.251
positive regulation of nucleobase containing compound metabolic processGO:0045935690.246
Human Zebrafish Worm Fly
macromolecule biosynthetic processGO:00090592270.242
Human Zebrafish Mouse Worm Fly
regulation of multicellular organismal processGO:00512392770.225
Zebrafish Fly
brain developmentGO:00074202930.224
cellular nitrogen compound biosynthetic processGO:00442712180.223
Human Zebrafish Mouse Worm Fly
ear developmentGO:00435831270.221
Mouse
dorsal ventral pattern formationGO:00099531250.219
regulation of macromolecule metabolic processGO:00602553170.211
Human Zebrafish Mouse Worm Fly
regulation of endodermal cell fate specificationGO:0042663150.209
axis specificationGO:0009798430.208
regulation of inner ear receptor cell differentiationGO:200098010.198
otic vesicle formationGO:0030916270.195
embryonic camera type eye morphogenesisGO:0048596190.194
regulation of cellular component organizationGO:0051128860.194
embryo development ending in birth or egg hatchingGO:00097922710.190
regulation of rna metabolic processGO:00512522240.187
Human Zebrafish Mouse Worm Fly
nucleobase containing compound metabolic processGO:00061392740.186
Human Zebrafish Mouse Worm Fly
cell surface receptor signaling pathway involved in heart developmentGO:0061311200.184
cell projection organizationGO:00300302840.183
Fly
regulation of rna biosynthetic processGO:20011412130.180
Human Zebrafish Mouse Worm Fly
embryonic heart tube developmentGO:00350501330.179
gland developmentGO:00487321430.178
cell motilityGO:00488702440.178
nitrogen compound metabolic processGO:00068073190.177
Human Zebrafish Mouse Worm Fly
regulation of developmental processGO:00507932470.176
Zebrafish Fly
regulation of signalingGO:00230512350.174
glial cell developmentGO:0021782200.172
negative regulation of cell fate specificationGO:0009996110.169
camera type eye morphogenesisGO:00485931080.165
determination of bilateral symmetryGO:00098552040.162
inner ear morphogenesisGO:0042472630.162
Mouse
regulation of response to stimulusGO:00485832690.159
embryonic eye morphogenesisGO:0048048300.155
muscle organ developmentGO:00075171010.154
axial mesodermal cell fate specificationGO:004832730.154
embryonic heart tube morphogenesisGO:00031431080.153
digestive tract developmentGO:00485652650.151
anterior posterior pattern specificationGO:00099521520.150
taxisGO:00423301090.150
collateral sprouting of intact axon in response to injuryGO:004867320.150
positive regulation of neural precursor cell proliferationGO:200017910.141
cell cell signaling involved in cell fate commitmentGO:0045168120.140
regulation of neural precursor cell proliferationGO:200017730.139
regulation of cell developmentGO:00602841000.136
Zebrafish Fly
organic substance biosynthetic processGO:19015762890.136
Human Zebrafish Mouse Worm Fly
response to external stimulusGO:00096052640.135
heart morphogenesisGO:00030071560.134
muscle structure developmentGO:00610611960.134
cell cycleGO:0007049930.133
neurological system processGO:0050877620.130
Zebrafish Worm
otic vesicle developmentGO:0071599420.129
muscle fiber developmentGO:0048747520.128
inner ear developmentGO:00488391260.123
Mouse
ear morphogenesisGO:0042471640.123
Mouse
muscle cell developmentGO:00550011150.121
heart developmentGO:00075073130.121
regulation of neurogenesisGO:0050767870.119
Fly
otic placode formationGO:0043049230.118
ectodermal placode developmentGO:0071696370.116
oligodendrocyte cell fate specificationGO:002177840.116
embryonic camera type eye developmentGO:0031076290.116
regulation of cell morphogenesis involved in differentiationGO:0010769380.115
striated muscle cell differentiationGO:00511461290.114
determination of left right symmetryGO:00073681790.112
regulation of cell growthGO:0001558290.111
neuroblast proliferationGO:000740520.111
positive regulation of cell communicationGO:0010647560.111
floor plate morphogenesisGO:0033505120.110
ectodermal placode morphogenesisGO:0071697320.109
localization of cellGO:00516742440.108
regionalizationGO:00030022740.106
endodermal cell fate specificationGO:0001714170.105
striated muscle tissue developmentGO:00147061100.105
regulation of locomotionGO:0040012550.104
negative regulation of axon regenerationGO:004868140.102
positive regulation of gene expressionGO:0010628710.100
Human Zebrafish Worm Fly
morphogenesis of an epitheliumGO:00020093330.099
epithelial tube morphogenesisGO:00605621480.099
stem cell proliferationGO:007208940.099
cell fate specificationGO:0001708680.099
Worm
eye field cell fate commitment involved in camera type eye formationGO:006089830.098
glial cell differentiationGO:0010001420.098
regulation of axonogenesisGO:0050770320.098
regulation of cell differentiationGO:00455951420.097
Zebrafish Fly
regulation of stem cell proliferationGO:007209120.097
rhombomere morphogenesisGO:0021593170.096
neuron projection guidanceGO:0097485860.095
ameboidal type cell migrationGO:00016671430.095
biosynthetic processGO:00090582940.094
Human Zebrafish Mouse Worm Fly
rhombomere formationGO:0021594120.094
locomotionGO:00400113130.094
negative regulation of signalingGO:0023057960.093
cardiac chamber formationGO:000320740.093
liver developmentGO:0001889960.088
regulation of cell morphogenesisGO:0022604420.088
facial nucleus developmentGO:002175470.088
skin developmentGO:0043588540.088
regulation of transcription involved in cell fate commitmentGO:006085010.088
larval developmentGO:000216420.087
sensory organ morphogenesisGO:00905962000.086
Zebrafish Mouse Fly
regulation of biosynthetic processGO:00098892500.085
Human Zebrafish Mouse Worm Fly
regulation of transcription dna templatedGO:00063552130.085
Human Zebrafish Mouse Worm Fly
regulation of cellular metabolic processGO:00313233200.084
Human Zebrafish Mouse Worm Fly
notochord morphogenesisGO:0048570170.083
cell migration involved in gastrulationGO:0042074790.083
negative regulation of nucleic acid templated transcriptionGO:1903507450.083
Fly
photoreceptor cell differentiationGO:0046530550.083
Zebrafish Fly
regulation of cell communicationGO:00106462320.082
neural tube developmentGO:0021915620.082
cell cell recognitionGO:000998810.082
determination of dorsal ventral asymmetryGO:0048262340.081
positive regulation of macromolecule metabolic processGO:0010604930.080
Human Zebrafish Worm Fly
positive regulation of cellular processGO:00485222010.080
Human Zebrafish Worm Fly
muscle tissue developmentGO:00605371100.079
regulation of wnt signaling pathwayGO:0030111530.078
cell part morphogenesisGO:00329902460.076
Fly
reproductionGO:0000003400.076
odontogenesis of dentin containing toothGO:004247510.075
positive regulation of biological processGO:00485182530.073
Human Zebrafish Worm Fly
maintenance of locationGO:005123540.072
rhombomere boundary formationGO:0021654100.072
regulation of neural retina developmentGO:006107420.071
neuroblast differentiationGO:001401610.071
behaviorGO:0007610740.071
Worm
developmental growthGO:00485891660.069
forebrain dorsal ventral pattern formationGO:002179810.069
transcription from rna polymerase ii promoterGO:0006366800.069
Human Mouse Worm Fly
negative regulation of mesodermal cell fate specificationGO:004266230.068
positive regulation of nitrogen compound metabolic processGO:0051173690.068
Human Zebrafish Worm Fly
negative regulation of gastrulationGO:2000542110.068
growthGO:00400071740.068
motor neuron axon guidanceGO:0008045230.067
positive regulation of signal transductionGO:0009967560.067
negative regulation of rna metabolic processGO:0051253480.066
Fly
negative regulation of transcription dna templatedGO:0045892450.066
Fly
embryonic cranial skeleton morphogenesisGO:0048701900.065
muscle cell differentiationGO:00426921390.065
regulation of cellular macromolecule biosynthetic processGO:20001122220.064
Human Zebrafish Mouse Worm Fly
striated muscle cell developmentGO:00550021080.064
negative regulation of reproductive processGO:200024230.063
fin morphogenesisGO:0033334530.063
endodermal cell differentiationGO:0035987190.062
positive regulation of rna biosynthetic processGO:1902680570.062
Human Zebrafish Worm Fly
axon extensionGO:0048675450.062
pons developmentGO:0021548110.061
optic placode formation involved in camera type eye formationGO:004661930.061
primary neural tube formationGO:001402010.060
heart loopingGO:0001947940.060
cell differentiation in spinal cordGO:0021515400.060
neural nucleus developmentGO:0048857150.059
regulation of axon extensionGO:0030516240.057
establishment of localizationGO:00512342440.057
regulation of bmp signaling pathway involved in heart joggingGO:2000223120.057
skeletal muscle organ developmentGO:0060538780.057
mesodermal cell fate specificationGO:0007501120.057
organelle localizationGO:0051640490.056
negative regulation of nervous system developmentGO:0051961220.056
determination of left right asymmetry in diencephalonGO:003546240.055
enzyme linked receptor protein signaling pathwayGO:00071671060.055
positive regulation of transcription dna templatedGO:0045893570.054
Human Zebrafish Worm Fly
cell cycle processGO:0022402530.054
skeletal system developmentGO:00015011810.053
regulation of cell proliferationGO:0042127370.053
positive regulation of stem cell proliferationGO:200064810.053
chemotaxisGO:00069351040.053
negative regulation of nitrogen compound metabolic processGO:0051172590.052
Fly
optic placode formationGO:000174340.052
regulation of transcription from rna polymerase ii promoterGO:00063571140.051
Human Mouse Worm Fly
otic vesicle morphogenesisGO:0071600340.051
regulation of developmental growthGO:0048638380.051
regulation of nucleobase containing compound metabolic processGO:00192192500.051
Human Zebrafish Mouse Worm Fly
sensory perceptionGO:0007600390.051
Zebrafish Worm
regulation of cardiac chamber morphogenesisGO:190121920.050
regulation of cell fate commitmentGO:0010453220.049
segmentationGO:0035282970.049
Fly
developmental inductionGO:0031128100.049
bmp signaling pathwayGO:0030509520.049
single organism cellular localizationGO:1902580460.049
negative regulation of nucleobase containing compound metabolic processGO:0045934590.048
Fly
organ formationGO:0048645170.048
embryonic camera type eye formationGO:0060900100.048
regulation of metabolic processGO:00192223590.048
Human Zebrafish Mouse Worm Fly
pharyngeal muscle developmentGO:004328240.048
adenohypophysis developmentGO:0021984150.048
peripheral nervous system neuron developmentGO:0048935220.048
metencephalon developmentGO:0022037270.048
Mouse
neural retina developmentGO:0003407490.048
cell proliferation in forebrainGO:002184630.047
developmental growth involved in morphogenesisGO:0060560860.046
fin developmentGO:0033333770.045
compound eye developmentGO:004874920.045
Fly
axial mesoderm formationGO:004832040.045
wnt signaling pathwayGO:0016055800.043
regulation of cellular biosynthetic processGO:00313262450.043
Human Zebrafish Mouse Worm Fly
regulation of skeletal muscle tissue developmentGO:004864140.043
heart formationGO:0060914130.043
neuron fate specificationGO:0048665200.043
Worm
cellular component assemblyGO:00226071700.043
notch signaling pathwayGO:0007219350.043
hindbrain formationGO:002157630.042
negative regulation of macromolecule biosynthetic processGO:0010558480.042
Fly
neural plate regionalizationGO:0060897100.042
developmental cell growthGO:0048588520.041
mesenchymal cell developmentGO:0014031780.041
determination of left right asymmetry in nervous systemGO:003554540.041
negative regulation of cell developmentGO:0010721260.041
Zebrafish
floor plate formationGO:0021508120.041
retina morphogenesis in camera type eyeGO:0060042790.041
cell fate commitment involved in formation of primary germ layerGO:0060795260.041
eye photoreceptor cell developmentGO:0042462300.040
Zebrafish Fly
cardioblast migration to the midline involved in heart field formationGO:006097570.040
regulation of multicellular organism growthGO:004001440.039
cellular localizationGO:0051641970.039
somite developmentGO:0061053960.039
regulation of neuron differentiationGO:0045664560.038
Fly
peripheral nervous system neuron axonogenesisGO:0048936130.038
macromolecule localizationGO:0033036540.038
regulation of heart morphogenesisGO:2000826170.038
microtubule based processGO:0007017600.037
negative regulation of endodermal cell fate specificationGO:004266480.037
rhombomere developmentGO:0021546190.037
regulation of organ growthGO:004662030.037
phosphorus metabolic processGO:00067931090.037
spinal cord oligodendrocyte cell fate specificationGO:002153020.036
positive regulation of catabolic processGO:000989640.036
bmp signaling pathway involved in heart joggingGO:0003303140.036
positive regulation of cell fate commitmentGO:001045510.036
neural crest cell differentiationGO:0014033720.035
pigmentationGO:0043473850.035
negative regulation of rna biosynthetic processGO:1902679450.035
Fly
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:1900094170.034
anterior posterior axis specificationGO:0009948200.034
regenerationGO:0031099910.034
embryonic skeletal system morphogenesisGO:0048704930.033
nerve developmentGO:0021675450.032
mesoderm developmentGO:0007498880.032
negative regulation of endodermal cell differentiationGO:190322580.032
forebrain regionalizationGO:002187140.032
ventral midline developmentGO:0007418130.032
myotube differentiationGO:0014902450.031
regulation of cytoplasmic transportGO:190364940.031
somitogenesisGO:0001756870.030
neural precursor cell proliferationGO:0061351200.030
positive regulation of rna metabolic processGO:0051254590.030
Human Zebrafish Worm Fly
spinal cord oligodendrocyte cell differentiationGO:002152950.030
cardioblast migrationGO:000326070.030
response to stressGO:00069502630.030
regulation of mechanoreceptor differentiationGO:004563110.030
pectoral fin developmentGO:0033339500.029
negative regulation of response to stimulusGO:00485851040.029
negative regulation of biological processGO:00485193040.029
Zebrafish Fly
single organism metabolic processGO:00447102170.029
forebrain anterior posterior pattern specificationGO:002179730.028
mesenchymal cell differentiationGO:0048762870.028
cell fate specification involved in pattern specificationGO:006057330.028
endodermal cell fate determinationGO:000749320.028
neural plate pattern specificationGO:0060896120.028
apoptotic processGO:00069151160.028
endodermal cell fate commitmentGO:0001711180.028
mesodermal cell fate commitmentGO:0001710140.027
epidermis developmentGO:0008544480.027
phosphate containing compound metabolic processGO:00067961080.027
convergent extension involved in gastrulationGO:0060027710.027
cellular component assembly involved in morphogenesisGO:00109271070.027
regulation of gastrulationGO:0010470240.027
positive regulation of nucleic acid templated transcriptionGO:1903508570.027
Human Zebrafish Worm Fly
bmp signaling pathway involved in determination of left right symmetryGO:0003154140.027
embryonic digestive tract morphogenesisGO:004855730.027
protein metabolic processGO:00195381830.027
regulation of transcription from rna polymerase iii promoterGO:000635910.027
gabaergic neuron differentiationGO:009715420.026
skeletal muscle fiber developmentGO:0048741350.026
negative regulation of gliogenesisGO:001401410.026
negative regulation of chromosome organizationGO:200125110.026
mitotic cell cycle processGO:1903047480.026
cranial nerve developmentGO:0021545420.026
palate developmentGO:006002180.025
paraxial mesodermal cell differentiationGO:004834220.025
neural crest cell developmentGO:0014032620.025
kupffer s vesicle developmentGO:0070121500.025
midbrain developmentGO:0030901280.025
regulation of extent of cell growthGO:0061387290.025
positive regulation of biosynthetic processGO:0009891680.025
Human Zebrafish Worm Fly
skeletal muscle tissue developmentGO:0007519670.025
heart field specificationGO:000312810.025
negative regulation of embryonic developmentGO:0045992110.025
organelle organizationGO:00069962270.024
Fly
eye photoreceptor cell differentiationGO:0001754450.024
Zebrafish Fly
positive regulation of muscle tissue developmentGO:190186310.024
cell cell signalingGO:0007267520.024
notochord developmentGO:0030903540.024
establishment of mitotic spindle orientationGO:0000132100.024
astrocyte differentiationGO:004870810.023
stem cell maintenanceGO:001982740.023
connective tissue developmentGO:0061448990.023
non canonical wnt signaling pathwayGO:0035567130.023
regulation of collateral sproutingGO:004867070.023
negative regulation of metabolic processGO:0009892860.023
Fly
stem cell developmentGO:0048864820.023
regulation of protein complex assemblyGO:004325430.023
positive regulation of embryonic developmentGO:004001930.023
regulation of neuron projection developmentGO:0010975400.023
positive regulation of macromolecule biosynthetic processGO:0010557590.022
Human Zebrafish Worm Fly
camera type eye photoreceptor cell differentiationGO:0060219190.022
negative regulation of muscle cell differentiationGO:005114810.022
retina layer formationGO:0010842240.022
optic nerve developmentGO:0021554150.022
angioblast cell migrationGO:003547690.022
response to organic substanceGO:00100331530.022
Zebrafish
regulation of cell fate specificationGO:0042659200.021
bmp signaling pathway involved in heart developmentGO:0061312150.021
cell proliferationGO:0008283800.021
regulation of notch signaling pathwayGO:0008593160.021
positive regulation of neuron migrationGO:200122420.021
forebrain developmentGO:0030900960.021
Mouse
regulation of protein transportGO:005122330.021
cell fate commitment involved in pattern specificationGO:006058160.021
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.020
immune system developmentGO:00025201910.020
adult behaviorGO:003053420.020
blood vessel morphogenesisGO:00485142160.020
cardiac cell fate commitmentGO:006091110.020
oocyte maturationGO:000155640.020
embryonic retina morphogenesis in camera type eyeGO:0060059220.020
multicellular organism growthGO:003526440.020
specification of organ identityGO:001009220.019
regulation of cellular response to growth factor stimulusGO:0090287350.019
neuron projection extensionGO:1990138450.019
negative regulation of histone modificationGO:003105710.019
pituitary gland developmentGO:0021983160.019
glial cell migrationGO:000834730.019
protein import into nucleusGO:000660630.019
positive regulation of metabolic processGO:00098931080.019
Human Zebrafish Worm Fly
mesenchymal cell proliferationGO:001046310.019
floor plate developmentGO:0033504150.018
cellular protein modification processGO:00064641000.018
regulation of cell cycleGO:0051726520.018
regulation of cellular response to drugGO:200103810.018
positive regulation of cell cycleGO:004578730.018
gastrulationGO:00073692080.018
negative regulation of cell differentiationGO:0045596460.018
Zebrafish
optic cup morphogenesis involved in camera type eye developmentGO:000207270.018
cellular protein catabolic processGO:004425740.018
stem cell fate commitmentGO:004886510.017
single organism organelle organizationGO:19025891990.017
protein modification processGO:00362111000.017
morphogenesis of an epithelial sheetGO:0002011490.017
positive regulation of epithelial cell differentiationGO:003085820.017
cell growthGO:0016049570.017
central nervous system neuron differentiationGO:0021953740.017
extracellular fibril organizationGO:004320610.017
regulation of embryonic developmentGO:0045995470.017
formation of anatomical boundaryGO:0048859140.016
mitotic cell cycleGO:0000278640.016
myotube cell developmentGO:0014904350.016
female gamete generationGO:0007292140.016
cerebellum formationGO:002158820.016
cellular response to growth factor stimulusGO:0071363390.016
neural tube patterningGO:0021532330.016
regulation of organelle organizationGO:0033043290.016
angiogenesisGO:00015251580.016
negative regulation of cellular metabolic processGO:0031324770.016
Fly
negative regulation of protein complex assemblyGO:003133310.016
regulation of growthGO:0040008420.016
central nervous system neuron axonogenesisGO:0021955180.015
retinal pigment epithelium developmentGO:000340680.015
negative regulation of striated muscle cell differentiationGO:005115410.015
cell proliferation in hindbrainGO:002153440.015
establishment of protein localization to organelleGO:007259440.015
endocrine system developmentGO:0035270650.015
negative regulation of wnt signaling pathwayGO:0030178300.015
establishment of organelle localizationGO:0051656450.015
cartilage developmentGO:0051216960.015
endoderm formationGO:0001706290.015
mesenchyme developmentGO:00604851270.015
lipid storageGO:001991510.015
positive regulation of cellular metabolic processGO:0031325940.015
Human Zebrafish Worm Fly
proteolysis involved in cellular protein catabolic processGO:005160330.015
modification dependent macromolecule catabolic processGO:004363230.015
blood vessel developmentGO:00015682460.015
regulation of endodermal cell differentiationGO:1903224150.015
photoreceptor cell developmentGO:0042461400.015
Zebrafish Fly
regulation of mesenchymal cell proliferationGO:001046410.014
regulation of molecular functionGO:0065009700.014
wound healingGO:0042060900.014
anterior commissure morphogenesisGO:002196030.014
histone h3 k27 methylationGO:007073420.014
regulation of mesoderm developmentGO:2000380110.014
peripheral nervous system neuron differentiationGO:0048934280.014
positive regulation of cellular component biogenesisGO:004408930.014
positive regulation of reproductive processGO:200024320.014
positive regulation of developmental processGO:0051094500.014
Fly
photoreceptor cell fate commitmentGO:004655210.014
Fly
regulation of organ morphogenesisGO:2000027350.014
Zebrafish Fly
formation of primary germ layerGO:0001704620.014
positive regulation of striated muscle tissue developmentGO:004584410.014
water homeostasisGO:003010440.014
cellular response to decreased oxygen levelsGO:003629410.014
regulation of cellular localizationGO:0060341120.014
tube closureGO:006060610.014
protein localization to nucleusGO:003450430.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
cardiac muscle tissue developmentGO:0048738480.013
renal system developmentGO:0072001940.013

otx1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.075
musculoskeletal system diseaseDOID:1700.048
connective tissue diseaseDOID:6500.048
bone diseaseDOID:008000100.048
bone development diseaseDOID:008000600.048
nervous system diseaseDOID:86300.033
electroclinical syndromeDOID:005070100.033
central nervous system diseaseDOID:33100.033
epilepsy syndromeDOID:182600.033
brain diseaseDOID:93600.033
dysostosisDOID:193400.025
acrocephalosyndactyliaDOID:1296000.020
synostosisDOID:1197100.020
pfeiffer syndromeDOID:1470500.014
osteochondrodysplasiaDOID:225600.014
cleidocranial dysplasiaDOID:1399400.014