Danio rerio

31 known processes

otx1b

orthodenticle homolog 1b

(Aliases: cb769,fj99f05,zOtx1,otx1,wu:fj99f05)

otx1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
central nervous system developmentGO:00074173870.993
nucleobase containing compound biosynthetic processGO:00346542050.984
organic cyclic compound metabolic processGO:19013603010.979
cell proliferation in forebrainGO:002184630.977
rna metabolic processGO:00160702190.970
heterocycle metabolic processGO:00464832900.962
nucleic acid metabolic processGO:00903042440.959
gene expressionGO:00104672520.948
regulation of primary metabolic processGO:00800903110.933
heterocycle biosynthetic processGO:00181302150.931
regulation of macromolecule biosynthetic processGO:00105562250.925
cellular aromatic compound metabolic processGO:00067252950.918
regulation of biosynthetic processGO:00098892500.916
aromatic compound biosynthetic processGO:00194382170.916
sensory organ morphogenesisGO:00905962000.913
forebrain generation of neuronsGO:0021872140.906
regulation of nucleic acid templated transcriptionGO:19035062130.901
neuron differentiationGO:00301823530.901
forebrain regionalizationGO:002187140.898
regulation of gene expressionGO:00104682650.875
cellular biosynthetic processGO:00442492860.872
camera type eye morphogenesisGO:00485931080.868
sensory organ developmentGO:00074233930.857
forebrain developmentGO:0030900960.853
forebrain anterior posterior pattern specificationGO:002179730.847
forebrain neuron fate commitmentGO:002187710.844
photoreceptor cell developmentGO:0042461400.838
regulation of transcription dna templatedGO:00063552130.833
nucleobase containing compound metabolic processGO:00061392740.830
segmentationGO:0035282970.810
axon guidanceGO:0007411860.806
regulation of metabolic processGO:00192223590.806
transcription dna templatedGO:00063511810.800
head developmentGO:00603223030.787
cellular nitrogen compound metabolic processGO:00346412900.786
photoreceptor cell differentiationGO:0046530550.785
cellular component morphogenesisGO:00329893360.776
diencephalon developmentGO:0021536580.772
regulation of cellular biosynthetic processGO:00313262450.770
regulation of inner ear receptor cell differentiationGO:200098010.766
negative regulation of gene expressionGO:0010629650.756
larval developmentGO:000216420.747
organic substance biosynthetic processGO:19015762890.738
digestive tract developmentGO:00485652650.731
endoderm developmentGO:0007492490.725
organic cyclic compound biosynthetic processGO:19013622230.723
regulation of macromolecule metabolic processGO:00602553170.722
regulation of nucleobase containing compound metabolic processGO:00192192500.720
brain developmentGO:00074202930.702
rna biosynthetic processGO:00327741810.700
macromolecule biosynthetic processGO:00090592270.673
camera type eye developmentGO:00430102220.671
neuron developmentGO:00486662620.670
eye developmentGO:00016542770.663
digestive tract morphogenesisGO:00485462310.660
chordate embryonic developmentGO:00430092710.658
cellular macromolecule biosynthetic processGO:00346452240.642
regulation of cellular metabolic processGO:00313233200.636
nitrogen compound metabolic processGO:00068073190.635
regionalizationGO:00030022740.630
regulation of rna metabolic processGO:00512522240.608
regulation of cellular macromolecule biosynthetic processGO:20001122220.607
nucleic acid templated transcriptionGO:00976591810.598
response to chemicalGO:00422213200.584
regulation of mechanoreceptor differentiationGO:004563110.573
neuron fate determinationGO:004866420.571
anterior posterior pattern specificationGO:00099521520.570
midbrain developmentGO:0030901280.568
embryonic retina morphogenesis in camera type eyeGO:0060059220.566
cell migrationGO:00164772370.566
localization of cellGO:00516742440.562
heart loopingGO:0001947940.554
digestive system developmentGO:00551232890.537
eye morphogenesisGO:00485921440.525
limbic system developmentGO:0021761160.523
eye photoreceptor cell differentiationGO:0001754450.522
ear developmentGO:00435831270.517
blood vessel morphogenesisGO:00485142160.505
neural crest cell differentiationGO:0014033720.501
axon developmentGO:00615641660.491
wnt signaling pathwayGO:0016055800.487
negative regulation of nucleic acid templated transcriptionGO:1903507450.483
morphogenesis of an epitheliumGO:00020093330.480
ectodermal placode developmentGO:0071696370.479
regulation of multicellular organismal developmentGO:20000262230.479
generation of neuronsGO:00486993850.474
neuron fate commitmentGO:0048663260.463
cell fate commitmentGO:0045165990.463
epidermal cell fate specificationGO:000995740.459
biosynthetic processGO:00090582940.456
cellular component movementGO:00069283350.455
signal transductionGO:00071654550.453
regulation of rna biosynthetic processGO:20011412130.452
ameboidal type cell migrationGO:00016671430.450
determination of left right symmetryGO:00073681790.443
cell surface receptor signaling pathwayGO:00071663250.441
blood vessel developmentGO:00015682460.440
negative regulation of neuron projection regenerationGO:007057140.440
nerve developmentGO:0021675450.436
cell morphogenesis involved in differentiationGO:00009041950.424
cellular macromolecule metabolic processGO:00442603910.414
auditory receptor cell fate commitmentGO:000991240.413
embryo development ending in birth or egg hatchingGO:00097922710.412
neural tube developmentGO:0021915620.410
regulation of transcription from rna polymerase ii promoterGO:00063571140.403
mammillary body developmentGO:002176740.402
retina morphogenesis in camera type eyeGO:0060042790.401
dopaminergic neuron differentiationGO:0071542140.399
negative regulation of transcription dna templatedGO:0045892450.394
olfactory lobe developmentGO:002198840.387
regulation of nitrogen compound metabolic processGO:00511712510.383
positive regulation of metabolic processGO:00098931080.383
embryonic organ morphogenesisGO:00485622740.379
cardioblast migrationGO:000326070.375
inner ear developmentGO:00488391260.371
negative regulation of gliogenesisGO:001401410.360
brain morphogenesisGO:0048854180.357
forebrain neuron differentiationGO:0021879140.336
negative regulation of cellular biosynthetic processGO:0031327550.325
eye photoreceptor cell developmentGO:0042462300.318
retina layer formationGO:0010842240.312
neuron projection guidanceGO:0097485860.305
artery developmentGO:0060840220.304
fin morphogenesisGO:0033334530.300
enzyme linked receptor protein signaling pathwayGO:00071671060.298
lens development in camera type eyeGO:0002088220.294
regulation of multicellular organismal processGO:00512392770.294
reproductive processGO:0022414400.293
determination of bilateral symmetryGO:00098552040.290
ear morphogenesisGO:0042471640.289
inner ear receptor cell fate commitmentGO:006012040.287
retinal cell programmed cell deathGO:004666620.285
cell morphogenesisGO:00009022890.285
gland developmentGO:00487321430.279
embryonic heart tube morphogenesisGO:00031431080.279
gastrulationGO:00073692080.273
ventral spinal cord interneuron specificationGO:002152130.272
neural tube patterningGO:0021532330.269
specification of symmetryGO:00097992040.268
angiogenesisGO:00015251580.267
negative regulation of cell developmentGO:0010721260.260
primary neural tube formationGO:001402010.259
mesenchymal cell developmentGO:0014031780.252
forebrain dorsal ventral pattern formationGO:002179810.250
locomotionGO:00400113130.246
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.242
negative regulation of collateral sprouting of intact axon in response to injuryGO:004868520.241
negative regulation of leukocyte differentiationGO:190210610.238
response to organic substanceGO:00100331530.237
single organism metabolic processGO:00447102170.236
regulation of oligodendrocyte differentiationGO:004871310.232
metencephalon developmentGO:0022037270.231
diencephalon morphogenesisGO:004885250.231
regulation of neural precursor cell proliferationGO:200017730.228
neuroblast proliferationGO:000740520.227
neuron projection morphogenesisGO:00488121610.226
embryonic eye morphogenesisGO:0048048300.222
determination of heart left right asymmetryGO:00613711170.220
hematopoietic or lymphoid organ developmentGO:00485341910.220
immune system developmentGO:00025201910.218
axonogenesisGO:00074091520.214
spinal cord oligodendrocyte cell fate specificationGO:002153020.214
negative regulation of macromolecule metabolic processGO:0010605760.213
vasculature developmentGO:00019442780.211
positive regulation of nervous system developmentGO:0051962250.209
lens morphogenesis in camera type eyeGO:000208970.207
negative regulation of biological processGO:00485193040.206
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.202
tube morphogenesisGO:00352393490.199
regulation of signal transductionGO:00099662250.196
stem cell maintenanceGO:001982740.193
vasculogenesisGO:0001570410.193
thalamus developmentGO:002179460.192
heart morphogenesisGO:00030071560.192
forebrain midbrain boundary formationGO:002190510.190
olfactory bulb developmentGO:002177240.189
negative regulation of macromolecule biosynthetic processGO:0010558480.186
dorsal ventral pattern formationGO:00099531250.185
sexual reproductionGO:0019953360.180
response to abiotic stimulusGO:00096281220.179
positive regulation of jun kinase activityGO:004350720.179
regulation of cell communicationGO:00106462320.179
midbrain hindbrain boundary morphogenesisGO:002155550.178
oligodendrocyte differentiationGO:0048709230.175
nose developmentGO:004358430.174
cell proliferation in hindbrainGO:002153440.173
mechanoreceptor differentiationGO:0042490370.173
forebrain neuron developmentGO:002188470.172
rostrocaudal neural tube patterningGO:0021903290.172
negative regulation of nitrogen compound metabolic processGO:0051172590.171
positive regulation of gene expressionGO:0010628710.170
maintenance of locationGO:005123540.169
somitogenesisGO:0001756870.169
neural precursor cell proliferationGO:0061351200.163
endodermal cell differentiationGO:0035987190.163
negative regulation of biosynthetic processGO:0009890550.163
negative regulation of collateral sproutingGO:004867120.163
body morphogenesisGO:0010171160.160
photoreceptor cell fate commitmentGO:004655210.157
glial cell fate specificationGO:002178040.156
developmental pigmentationGO:0048066480.156
inner ear morphogenesisGO:0042472630.155
kidney developmentGO:0001822920.154
neural crest cell developmentGO:0014032620.153
central nervous system myelinationGO:002201020.151
wound healingGO:0042060900.150
neural crest cell migrationGO:0001755420.148
embryonic pattern specificationGO:0009880440.148
negative regulation of nucleobase containing compound metabolic processGO:0045934590.148
regenerationGO:0031099910.147
negative regulation of rna metabolic processGO:0051253480.147
columnar cuboidal epithelial cell differentiationGO:0002065380.147
epithelial tube morphogenesisGO:00605621480.146
response to external stimulusGO:00096052640.145
oligodendrocyte cell fate specificationGO:002177840.144
regulation of cell differentiationGO:00455951420.143
endodermal cell fate determinationGO:000749320.143
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.141
positive regulation of multicellular organismal processGO:0051240520.138
cell motilityGO:00488702440.138
gamete generationGO:0007276330.136
negative regulation of mitosisGO:004583930.136
dna methylation on cytosineGO:003277630.135
synaptic target recognitionGO:000803910.132
telencephalon developmentGO:0021537140.131
cellular process involved in reproduction in multicellular organismGO:0022412280.131
ectodermal placode formationGO:0060788260.130
forebrain morphogenesisGO:004885360.130
pons developmentGO:0021548110.129
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.129
axis elongation involved in somitogenesisGO:009024520.128
protein importGO:001703830.127
cellular response to fatty acidGO:007139830.127
negative chemotaxisGO:005091910.126
heart developmentGO:00075073130.126
facial nucleus developmentGO:002175470.125
regulation of collateral sprouting of intact axon in response to injuryGO:004868320.124
negative regulation of cellular processGO:00485232830.122
neuron projection developmentGO:00311751800.122
mesoderm developmentGO:0007498880.122
abducens nucleus developmentGO:002174220.122
embryonic skeletal system developmentGO:0048706970.122
embryonic camera type eye developmentGO:0031076290.120
negative regulation of response to stimulusGO:00485851040.118
cerebellum formationGO:002158820.118
phosphorus metabolic processGO:00067931090.117
stem cell developmentGO:0048864820.116
multicellular organism growthGO:003526440.116
regulation of response to stimulusGO:00485832690.115
pituitary gland developmentGO:0021983160.115
taxisGO:00423301090.115
neuroblast differentiationGO:001401610.114
lateral line system developmentGO:0048925760.114
cellular component assembly involved in morphogenesisGO:00109271070.114
lipid storageGO:001991510.113
cell morphogenesis involved in neuron differentiationGO:00486671630.111
limb bud formationGO:006017420.110
positive regulation of biosynthetic processGO:0009891680.110
pectoral fin morphogenesisGO:0035138290.109
embryonic organ developmentGO:00485683810.109
spermatid developmentGO:000728620.109
cell part morphogenesisGO:00329902460.108
circadian regulation of gene expressionGO:003292280.108
cell cell recognitionGO:000998810.107
hindbrain developmentGO:0030902910.107
cilium morphogenesisGO:0060271850.106
cell proliferation in midbrainGO:003327840.106
peripheral nervous system developmentGO:0007422550.106
hair cell differentiationGO:0035315320.105
determination of pancreatic left right asymmetryGO:0035469110.105
stem cell differentiationGO:00488631170.104
regulation of neuron differentiationGO:0045664560.104
leukocyte activationGO:0045321120.104
cellular nitrogen compound biosynthetic processGO:00442712180.103
cell cell signaling involved in cell fate commitmentGO:0045168120.103
multi organism processGO:00517041340.101
regulation of cell developmentGO:00602841000.100
striated muscle tissue developmentGO:00147061100.100
regulation of anatomical structure morphogenesisGO:00226031300.097
otic vesicle morphogenesisGO:0071600340.097
convergent extensionGO:00600261180.096
mesoderm morphogenesisGO:0048332510.096
somite specificationGO:0001757120.095
negative regulation of multicellular organismal processGO:0051241690.094
tube closureGO:006060610.094
retina development in camera type eyeGO:00600411460.094
positive regulation of neuron migrationGO:200122420.093
odontogenesis of dentin containing toothGO:004247510.093
brain segmentationGO:003528460.091
regulation of glial cell differentiationGO:004568540.091
regulation of nervous system developmentGO:0051960900.090
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.090
camera type eye photoreceptor cell differentiationGO:0060219190.090
anterior posterior axis specificationGO:0009948200.089
methylationGO:0032259220.088
axon ensheathment in central nervous systemGO:003229120.088
regulation of signalingGO:00230512350.088
developmental process involved in reproductionGO:0003006270.088
transcription from rna polymerase ii promoterGO:0006366800.087
epithelial cell differentiationGO:00308551160.085
cardioblast migration to the midline involved in heart field formationGO:006097570.085
pigmentationGO:0043473850.084
hypothalamus cell differentiationGO:002197940.083
protein metabolic processGO:00195381830.082
muscle tissue developmentGO:00605371100.082
embryonic heart tube developmentGO:00350501330.081
somite developmentGO:0061053960.080
regulation of developmental processGO:00507932470.080
retinal ganglion cell axon guidanceGO:0031290350.079
embryonic camera type eye morphogenesisGO:0048596190.079
retinal pigment epithelium developmentGO:000340680.079
axial mesoderm morphogenesisGO:004831980.078
response to drugGO:004249330.076
circulatory system processGO:0003013870.075
germ cell developmentGO:0007281220.075
phosphate containing compound metabolic processGO:00067961080.075
mesenchymal cell differentiationGO:0048762870.074
astrocyte differentiationGO:004870810.073
renal system developmentGO:0072001940.072
auditory receptor cell fate determinationGO:004266820.071
radial glial cell differentiationGO:006001920.071
response to stressGO:00069502630.070
positive regulation of canonical wnt signaling pathwayGO:009026340.070
positive regulation of rna biosynthetic processGO:1902680570.069
meiotic nuclear divisionGO:000712640.069
inner ear receptor cell differentiationGO:0060113290.067
dorsal ventral axis specificationGO:0009950140.067
development of primary female sexual characteristicsGO:004654540.067
pancreatic a cell developmentGO:000332220.067
heart joggingGO:0003146400.067
male meiosisGO:000714020.065
negative regulation of developmental processGO:0051093650.064
determination of dorsal ventral asymmetryGO:0048262340.063
regulation of cell fate commitmentGO:0010453220.063
convergent extension involved in organogenesisGO:0060029100.063
neural plate pattern specificationGO:0060896120.063
pharyngeal system developmentGO:0060037180.062
negative regulation of rna biosynthetic processGO:1902679450.061
regulation of wnt signaling pathwayGO:0030111530.061
rhombomere developmentGO:0021546190.061
negative regulation of cellular metabolic processGO:0031324770.061
positive regulation of stem cell proliferationGO:200064810.060
circadian rhythmGO:0007623190.059
primitive hemopoiesisGO:0060215270.059
formation of primary germ layerGO:0001704620.059
prechordal plate formationGO:002150130.059
regulation of gtp catabolic processGO:003312420.059
axis specificationGO:0009798430.059
adenohypophysis developmentGO:0021984150.058
urogenital system developmentGO:0001655970.058
negative regulation of signalingGO:0023057960.057
negative regulation of canonical wnt signaling pathwayGO:0090090210.056
innervationGO:006038430.055
eye field cell fate commitment involved in camera type eye formationGO:006089830.055
negative regulation of axon regenerationGO:004868140.055
ion transportGO:00068111140.054
lateral line ganglion developmentGO:004889020.054
positive regulation of nucleic acid templated transcriptionGO:1903508570.054
liver developmentGO:0001889960.054
positive regulation of cellular processGO:00485222010.054
motor neuron axon guidanceGO:0008045230.053
positive regulation of transcription dna templatedGO:0045893570.053
tissue regenerationGO:0042246740.053
multi organism reproductive processGO:0044703360.053
regulation of multicellular organism growthGO:004001440.053
cell fate specificationGO:0001708680.051
ventricular system developmentGO:0021591120.051
cell cycle processGO:0022402530.051
pronephros developmentGO:0048793690.051
androgen metabolic processGO:000820920.050
pancreatic d cell differentiationGO:000331120.050
establishment of protein localization to organelleGO:007259440.050
protein import into nucleusGO:000660630.050
negative regulation of neurogenesisGO:0050768200.050
response to amino acidGO:004320020.050
response to temperature stimulusGO:0009266150.050
epibolyGO:0090504410.049
neural plate anterior posterior regionalizationGO:002199980.049
gliogenesisGO:0042063450.049
midbrain hindbrain boundary developmentGO:0030917230.049
neural plate regionalizationGO:0060897100.049
nuclear transportGO:005116940.048
endodermal cell fate commitmentGO:0001711180.048
regulation of canonical wnt signaling pathwayGO:0060828340.048
multicellular organism reproductionGO:0032504350.048
positive regulation of biological processGO:00485182530.048
entrainment of circadian clock by photoperiodGO:004315310.048
cilium assemblyGO:0042384580.047
appendage morphogenesisGO:0035107560.047
response to fibroblast growth factorGO:0071774220.046
sympathetic nervous system developmentGO:004848530.046
central nervous system myelin formationGO:003228910.046
embryonic hemopoiesisGO:0035162530.044
positive regulation of transportGO:005105020.044
regulation of cell migrationGO:0030334400.043
nucleocytoplasmic transportGO:000691340.043
skeletal system morphogenesisGO:00487051020.043
negative regulation of axon extensionGO:003051770.043
chemotaxisGO:00069351040.043
spermatid differentiationGO:004851520.043
glial cell differentiationGO:0010001420.043
regulation of collateral sproutingGO:004867070.042
negative regulation of mapk cascadeGO:004340940.042
establishment of localizationGO:00512342440.041
fourth ventricle developmentGO:002159280.041
regulation of neuron projection developmentGO:0010975400.041
female sex differentiationGO:004666040.041
negative regulation of cell differentiationGO:0045596460.041
cell surface receptor signaling pathway involved in heart developmentGO:0061311200.041
negative regulation of neuron differentiationGO:0045665100.041
regulation of developmental growthGO:0048638380.040
spinal cord patterningGO:002151160.040
epithelium regenerationGO:1990399140.040
embryonic cranial skeleton morphogenesisGO:0048701900.040
mesodermal cell differentiationGO:0048333210.040
hemopoiesisGO:00300971830.040
adult behaviorGO:003053420.040
cellular response to organic substanceGO:00713101050.040
skeletal muscle organ developmentGO:0060538780.039
segment specificationGO:0007379120.039
inner ear receptor cell developmentGO:0060119200.039
atrioventricular valve formationGO:000319030.039
specification of organ identityGO:001009220.039
cartilage developmentGO:0051216960.039
neuron recognitionGO:0008038180.039
neuroepithelial cell differentiationGO:0060563260.039
collateral sprouting of intact axon in response to injuryGO:004867320.039
fin developmentGO:0033333770.039
mesenchyme developmentGO:00604851270.038
regulation of intracellular protein transportGO:003315730.038
septum transversum developmentGO:000334340.038
heart valve formationGO:000318840.038
locus ceruleus developmentGO:002170330.038
single organism reproductive processGO:0044702400.037
angioblast cell migrationGO:003547690.037
cell projection morphogenesisGO:00488582440.037
lateral inhibitionGO:004633110.037
response to woundingGO:00096111160.037
pancreas developmentGO:0031016840.037
cilium organizationGO:0044782710.036
gastrulation with mouth forming secondGO:0001702440.036
negative regulation of metabolic processGO:0009892860.036
organelle assemblyGO:00709251100.036
otic placode formationGO:0043049230.036
appendage developmentGO:0048736800.036
anatomical structure arrangementGO:004853220.036
regulation of protein import into nucleusGO:004230620.036
locomotory behaviorGO:0007626340.036
positive regulation of rna metabolic processGO:0051254590.036
optic placode formationGO:000174340.036
positive regulation of nucleobase containing compound metabolic processGO:0045935690.036
neuromast developmentGO:0048884460.035
myeloid cell homeostasisGO:0002262560.035
negative regulation of nervous system developmentGO:0051961220.034
positive regulation of jnk cascadeGO:004633030.034
ventral spinal cord interneuron fate commitmentGO:006057930.034
negative regulation of wnt signaling pathwayGO:0030178300.033
positive regulation of cell developmentGO:0010720250.033
glial cell developmentGO:0021782200.033
developmental growthGO:00485891660.033
angioblast cell migration involved in selective angioblast sproutingGO:003547540.033
macromolecule localizationGO:0033036540.033
regulation of stem cell proliferationGO:007209120.033
organ formationGO:0048645170.033
hepaticobiliary system developmentGO:0061008980.032
positive regulation of macromolecule metabolic processGO:0010604930.032
melanosome transportGO:0032402190.032
water homeostasisGO:003010440.032
regulation of purine nucleotide catabolic processGO:003312120.031
ectodermal placode morphogenesisGO:0071697320.031
organelle localizationGO:0051640490.031
iris morphogenesisGO:006107210.031
multicellular organismal reproductive processGO:0048609350.031
positive regulation of developmental processGO:0051094500.030
venous endothelial cell migration involved in lymph vessel developmentGO:006085540.030
spinal cord oligodendrocyte cell differentiationGO:002152950.030
embryonic camera type eye formationGO:0060900100.030
aorta morphogenesisGO:003590930.029
cellular response to prostaglandin stimulusGO:007137930.029
embryonic limb morphogenesisGO:003032620.029
negative regulation of epithelial cell proliferationGO:005068010.029
negative regulation of myeloid leukocyte differentiationGO:000276210.029
deathGO:00162651210.029
muscle structure developmentGO:00610611960.028
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003760.028
cell migration involved in heart formationGO:0060974100.028
regulation of establishment of protein localizationGO:007020140.028
entrainment of circadian clockGO:000964920.028
leukocyte differentiationGO:0002521250.028
peripheral nervous system neuron developmentGO:0048935220.028
embryonic pectoral fin morphogenesisGO:0035118240.028
embryonic viscerocranium morphogenesisGO:0048703520.028
neuron migrationGO:0001764220.027

otx1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
physical disorderDOID:008001500.156
congenital nervous system abnormalityDOID:249000.089
sensory system diseaseDOID:005015500.082
disease of anatomical entityDOID:700.082
nervous system diseaseDOID:86300.082
eye and adnexa diseaseDOID:149200.082