Danio rerio

6 known processes

thbs4b

thrombospondin 4b

(Aliases: thbs4,zgc:111910,tsp4)

thbs4b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic organ developmentGO:00485683810.219
aromatic compound biosynthetic processGO:00194382170.213
heterocycle metabolic processGO:00464832900.189
regulation of nitrogen compound metabolic processGO:00511712510.177
regulation of multicellular organismal processGO:00512392770.177
Human Mouse
transcription dna templatedGO:00063511810.173
skeletal system developmentGO:00015011810.151
larval developmentGO:000216420.149
morphogenesis of an epitheliumGO:00020093330.144
negative regulation of cellular processGO:00485232830.127
muscle structure developmentGO:00610611960.127
cellular macromolecule metabolic processGO:00442603910.126
Human
regulation of response to stimulusGO:00485832690.119
Human
cellular nitrogen compound biosynthetic processGO:00442712180.119
organic cyclic compound biosynthetic processGO:19013622230.114
regulation of cellular metabolic processGO:00313233200.113
Human
nucleobase containing compound biosynthetic processGO:00346542050.111
response to chemicalGO:00422213200.110
Human
nucleic acid metabolic processGO:00903042440.105
response to amino acidGO:004320020.103
signal transductionGO:00071654550.103
regulation of gene expressionGO:00104682650.101
nitrogen compound metabolic processGO:00068073190.099
convergent extensionGO:00600261180.096
macromolecule biosynthetic processGO:00090592270.095
digestive system developmentGO:00551232890.092
regulation of cellular biosynthetic processGO:00313262450.091
response to stressGO:00069502630.091
Mouse Rat
regulation of biological qualityGO:00650082630.090
cell surface receptor signaling pathwayGO:00071663250.084
negative regulation of biological processGO:00485193040.083
Human
nucleic acid templated transcriptionGO:00976591810.080
heterocycle biosynthetic processGO:00181302150.078
muscle cell differentiationGO:00426921390.078
sensory organ developmentGO:00074233930.077
digestive tract developmentGO:00485652650.074
skeletal system morphogenesisGO:00487051020.071
organic substance biosynthetic processGO:19015762890.070
gene expressionGO:00104672520.069
cell morphogenesisGO:00009022890.069
Rat
muscle fiber developmentGO:0048747520.069
regulation of developmental processGO:00507932470.068
Human
rna metabolic processGO:00160702190.068
cell substrate adhesionGO:003158940.068
maintenance of locationGO:005123540.067
system processGO:00030081850.067
muscle organ developmentGO:00075171010.067
localization of cellGO:00516742440.066
Human
tube morphogenesisGO:00352393490.066
cell motilityGO:00488702440.066
Human
response to nutrientGO:000758430.065
regulation of macromolecule biosynthetic processGO:00105562250.064
cellular aromatic compound metabolic processGO:00067252950.063
skeletal muscle organ developmentGO:0060538780.062
regulation of signalingGO:00230512350.062
regulation of cell substrate adhesionGO:001081010.061
fin regenerationGO:0031101510.061
response to drugGO:004249330.060
cellular component morphogenesisGO:00329893360.060
Rat
organic cyclic compound metabolic processGO:19013603010.058
regenerationGO:0031099910.056
cellular response to external stimulusGO:007149620.056
multicellular organismal macromolecule metabolic processGO:004425920.056
biosynthetic processGO:00090582940.055
positive regulation of biological processGO:00485182530.055
Human
notochord developmentGO:0030903540.055
digestive tract morphogenesisGO:00485462310.053
lipid storageGO:001991510.053
cell part morphogenesisGO:00329902460.053
Rat
regulation of macromolecule metabolic processGO:00602553170.053
Human
response to carbohydrateGO:000974330.052
gastrulationGO:00073692080.051
regulation of signal transductionGO:00099662250.051
rna biosynthetic processGO:00327741810.051
regulation of reproductive processGO:200024140.050
locomotionGO:00400113130.050
Human
response to external stimulusGO:00096052640.050
Human
mesoderm developmentGO:0007498880.050
eye developmentGO:00016542770.050
cellular macromolecule biosynthetic processGO:00346452240.049
response to woundingGO:00096111160.049
neuron differentiationGO:00301823530.048
Rat
regulation of rna biosynthetic processGO:20011412130.048
regulation of nucleobase containing compound metabolic processGO:00192192500.048
positive regulation of protein kinase b signalingGO:005189710.048
cellular biosynthetic processGO:00442492860.047
regulation of multicellular organismal developmentGO:20000262230.047
Human
meiotic nuclear divisionGO:000712640.047
cellular component biogenesisGO:00440851780.047
Rat
wound healingGO:0042060900.047
collagen fibril organizationGO:003019910.047
embryonic skeletal system developmentGO:0048706970.047
response to glucoseGO:000974930.046
cellular response to chemical stimulusGO:00708871570.046
Human
cell migrationGO:00164772370.046
Human
multicellular organism growthGO:003526440.046
regulation of nucleic acid templated transcriptionGO:19035062130.045
regionalizationGO:00030022740.045
regulation of rna metabolic processGO:00512522240.045
heart morphogenesisGO:00030071560.045
regulation of synapse assemblyGO:005196330.044
regulation of cellular macromolecule biosynthetic processGO:20001122220.044
sensory organ morphogenesisGO:00905962000.044
cellular component assemblyGO:00226071700.043
Rat
transportGO:00068102200.043
nucleobase containing compound metabolic processGO:00061392740.043
embryonic heart tube developmentGO:00350501330.043
developmental growthGO:00485891660.043
determination of left right symmetryGO:00073681790.042
chordate embryonic developmentGO:00430092710.042
positive regulation of mesenchymal cell proliferationGO:000205310.042
regulation of primary metabolic processGO:00800903110.041
Human
regulation of transcription dna templatedGO:00063552130.041
phagocytosisGO:000690930.041
ion transportGO:00068111140.041
regulation of metabolic processGO:00192223590.040
Human
single organism localizationGO:19025782250.040
regulation of cell differentiationGO:00455951420.040
blood vessel developmentGO:00015682460.040
Human
agingGO:000756820.040
determination of bilateral symmetryGO:00098552040.039
cell projection morphogenesisGO:00488582440.039
Rat
camera type eye developmentGO:00430102220.038
homeostatic processGO:00425921420.038
specification of symmetryGO:00097992040.038
blood vessel morphogenesisGO:00485142160.038
Human
cartilage developmentGO:0051216960.037
protein localization to nucleusGO:003450430.037
regulation of synapse organizationGO:005080730.037
negative regulation of response to stimulusGO:00485851040.037
protein metabolic processGO:00195381830.036
Human
muscle tissue developmentGO:00605371100.036
cellular component assembly involved in morphogenesisGO:00109271070.036
mitochondrion organizationGO:000700540.036
protein polymerizationGO:005125840.036
glial cell migrationGO:000834730.035
response to hexoseGO:000974630.035
cellular component movementGO:00069283350.034
Human
heart developmentGO:00075073130.034
striated muscle cell developmentGO:00550021080.034
growthGO:00400071740.034
multicellular organismal metabolic processGO:004423620.034
extracellular structure organizationGO:0043062270.033
neuron developmentGO:00486662620.032
Rat
response to corticosteroidGO:003196010.032
cellular nitrogen compound metabolic processGO:00346412900.032
response to vitaminGO:003327330.032
regulation of cell communicationGO:00106462320.031
tissue regenerationGO:0042246740.031
establishment of localizationGO:00512342440.031
regulation of cell projection assemblyGO:006049140.031
muscle cell developmentGO:00550011150.031
angiogenesisGO:00015251580.030
Human
positive regulation of blood circulationGO:190352420.030
regulation of stem cell differentiationGO:200073640.030
striated muscle tissue developmentGO:00147061100.030
negative regulation of gastrulationGO:2000542110.030
single organism transportGO:00447652060.029
purine ribonucleoside monophosphate catabolic processGO:000916940.029
growth plate cartilage developmentGO:000341720.029
positive regulation of transportGO:005105020.029
cellular response to organic substanceGO:00713101050.029
organelle assemblyGO:00709251100.029
positive regulation of cellular component biogenesisGO:004408930.029
embryonic organ morphogenesisGO:00485622740.028
positive regulation of cell cycleGO:004578730.028
response to organic substanceGO:00100331530.028
organonitrogen compound metabolic processGO:1901564740.028
cellular protein metabolic processGO:00442671290.028
Human
connective tissue developmentGO:0061448990.028
regulation of multicellular organism growthGO:004001440.027
stem cell differentiationGO:00488631170.027
positive regulation of cytokine productionGO:000181920.027
negative regulation of protein phosphorylationGO:000193340.027
circulatory system processGO:0003013870.026
embryo development ending in birth or egg hatchingGO:00097922710.026
eye morphogenesisGO:00485921440.026
neuron projection developmentGO:00311751800.026
Rat
neuromuscular synaptic transmissionGO:000727420.026
transcription from rna polymerase ii promoterGO:0006366800.026
regulation of cytoplasmic transportGO:190364940.026
dorsal ventral pattern formationGO:00099531250.026
organic acid metabolic processGO:0006082310.026
skeletal muscle tissue developmentGO:0007519670.026
regulation of skeletal muscle tissue developmentGO:004864140.025
taxisGO:00423301090.025
Human
striated muscle cell differentiationGO:00511461290.025
developmental growth involved in morphogenesisGO:0060560860.025
regulation of biosynthetic processGO:00098892500.024
negative regulation of developmental processGO:0051093650.024
Human
blood circulationGO:0008015870.024
regulation of myotube differentiationGO:001083020.024
cellular carbohydrate metabolic processGO:004426240.024
phosphorus metabolic processGO:00067931090.024
Human
hematopoietic or lymphoid organ developmentGO:00485341910.024
regulation of locomotionGO:0040012550.024
Human
cell morphogenesis involved in neuron differentiationGO:00486671630.024
enzyme linked receptor protein signaling pathwayGO:00071671060.024
central nervous system developmentGO:00074173870.024
cellular response to extracellular stimulusGO:003166820.024
regulation of blood vessel sizeGO:005088020.023
regulation of cellular component organizationGO:0051128860.023
immune system processGO:00023762410.023
Human
protein importGO:001703830.023
immune system developmentGO:00025201910.023
nucleoside monophosphate catabolic processGO:000912540.023
regulation of reactive oxygen species metabolic processGO:200037720.023
positive regulation of cell adhesionGO:004578510.022
cellular response to nutrient levelsGO:003166920.022
female sex differentiationGO:004666040.022
regulation of cell activationGO:005086510.022
response to hydrogen peroxideGO:004254230.022
negative regulation of cell differentiationGO:0045596460.022
regulation of cytokine productionGO:000181730.021
regulation of stem cell proliferationGO:007209120.021
cation transportGO:0006812810.021
vasculature developmentGO:00019442780.021
Human
pole plasm assemblyGO:000731540.021
myeloid cell differentiationGO:0030099860.021
meiotic cell cycle processGO:190304630.021
myotube cell developmentGO:0014904350.021
peptidyl threonine phosphorylationGO:001810710.020
negative regulation of synapse assemblyGO:005196420.020
rna localizationGO:000640340.020
embryonic skeletal system morphogenesisGO:0048704930.020
multi organism processGO:00517041340.020
proteolysis involved in cellular protein catabolic processGO:005160330.020
atp catabolic processGO:000620040.019
hemopoiesisGO:00300971830.019
negative regulation of endodermal cell differentiationGO:190322580.019
endochondral bone growthGO:000341620.019
regulation of carbohydrate metabolic processGO:000610940.019
negative regulation of cell communicationGO:0010648960.019
embryonic heart tube morphogenesisGO:00031431080.019
axonogenesisGO:00074091520.019
chondrocyte developmentGO:000206340.019
positive regulation of cellular metabolic processGO:0031325940.018
Human
response to oxygen containing compoundGO:1901700550.018
spermatid differentiationGO:004851520.018
axon guidanceGO:0007411860.018
camera type eye morphogenesisGO:00485931080.018
cytoplasm organizationGO:000702840.018
single organism nuclear importGO:190259330.018
response to abiotic stimulusGO:00096281220.018
negative regulation of signalingGO:0023057960.018
regulation of wound healingGO:006104120.018
synaptic growth at neuromuscular junctionGO:005112420.018
regulation of cellular component movementGO:0051270550.018
Human
regulation of mrna splicing via spliceosomeGO:004802430.018
negative regulation of embryonic developmentGO:0045992110.018
pronephros developmentGO:0048793690.017
endoderm developmentGO:0007492490.017
regulation of epithelial to mesenchymal transitionGO:001071730.017
axon developmentGO:00615641660.017
cell adhesionGO:0007155400.017
Human
regulation of anatomical structure morphogenesisGO:00226031300.017
Human
protein modification processGO:00362111000.017
Human
ear morphogenesisGO:0042471640.017
cellular amino acid metabolic processGO:000652070.017
phosphate containing compound metabolic processGO:00067961080.017
Human
macromolecule modificationGO:00434121110.017
Human
cell morphogenesis involved in differentiationGO:00009041950.017
negative regulation of map kinase activityGO:004340720.017
cell fate commitmentGO:0045165990.017
negative chemotaxisGO:005091910.017
protein targeting to nucleusGO:004474430.017
determination of heart left right asymmetryGO:00613711170.017
nuclear transportGO:005116940.017
skeletal muscle fiber developmentGO:0048741350.017
embryonic cranial skeleton morphogenesisGO:0048701900.017
mesoderm morphogenesisGO:0048332510.017
positive regulation of heart contractionGO:004582320.016
modulation by virus of host morphology or physiologyGO:001904810.016
cognitionGO:005089010.016
protein import into nucleusGO:000660630.016
regulation of protein complex assemblyGO:004325430.016
positive regulation of signal transductionGO:0009967560.016
positive regulation of macromolecule metabolic processGO:0010604930.016
Human
stem cell proliferationGO:007208940.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
cellular protein catabolic processGO:004425740.016
establishment of protein localization to organelleGO:007259440.016
positive regulation of nucleic acid templated transcriptionGO:1903508570.016
regulation of tube sizeGO:003515020.016
peptidyl threonine modificationGO:001821010.016
generation of neuronsGO:00486993850.016
Rat
cartilage development involved in endochondral bone morphogenesisGO:006035180.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
peptidyl serine phosphorylationGO:001810510.016
female gonad developmentGO:000858540.016
regulation of endodermal cell differentiationGO:1903224150.016
cell proliferationGO:0008283800.016
Human
fin developmentGO:0033333770.016
response to glucocorticoidGO:005138410.016
regulation of metal ion transportGO:001095940.016
cell cycle arrestGO:000705010.016
regulation of cellular amino acid metabolic processGO:000652100.016
myotube differentiationGO:0014902450.016
cellular response to biotic stimulusGO:007121630.015
central nervous system neuron differentiationGO:0021953740.015
response to inorganic substanceGO:0010035380.015
regulation of cellular amine metabolic processGO:003323800.015
lateral inhibitionGO:004633110.015
collagen metabolic processGO:003296320.015
cellular ketone metabolic processGO:0042180110.015
developmental cell growthGO:0048588520.015
renal system developmentGO:0072001940.015
release of sequestered calcium ion into cytosolGO:005120930.015
positive regulation of transcription dna templatedGO:0045893570.015
alcohol biosynthetic processGO:004616520.015
ribonucleoside monophosphate catabolic processGO:000915840.015
myofibril assemblyGO:0030239480.015
septum transversum developmentGO:000334340.015
developmental programmed cell deathGO:001062340.015
regulation of syncytium formation by plasma membrane fusionGO:006014220.015
regulation of cellular carbohydrate metabolic processGO:001067540.015
actin filament based processGO:0030029640.014
primary neural tube formationGO:001402010.014
heart processGO:0003015710.014
cellular protein modification processGO:00064641000.014
Human
cytokinesisGO:000091030.014
regulation of behaviorGO:0050795240.014
Human
regulation of alternative mrna splicing via spliceosomeGO:000038110.014
positive regulation of stem cell proliferationGO:200064810.014
response to monosaccharideGO:003428430.014
positive regulation of protein complex assemblyGO:003133420.014
reactive oxygen species metabolic processGO:007259360.014
macromolecular complex subunit organizationGO:0043933740.014
Rat
response to lipidGO:0033993600.014
regulation of localizationGO:00328791040.014
Human
response to steroid hormoneGO:0048545350.014
regulation of epithelial cell proliferationGO:005067830.014
Human
negative regulation of myeloid cell differentiationGO:004563810.014
inner ear morphogenesisGO:0042472630.014
apoptotic process involved in developmentGO:190274220.013
regulation of blood pressureGO:000821710.013
transmission of nerve impulseGO:0019226190.013
head developmentGO:00603223030.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.013
positive regulation of gene expressionGO:0010628710.013
carboxylic acid metabolic processGO:0019752220.013
negative regulation of leukocyte differentiationGO:190210610.013
regulation of establishment of protein localizationGO:007020140.013
positive regulation of biosynthetic processGO:0009891680.013
nuclear importGO:005117030.013
formation of primary germ layerGO:0001704620.013
membrane invaginationGO:001032410.013
cell growthGO:0016049570.013
regulation of chondrocyte differentiationGO:003233010.013
amine metabolic processGO:000930820.013
purine nucleoside monophosphate catabolic processGO:000912840.013
regulation of cell growthGO:0001558290.013
regulation of oocyte developmentGO:006028130.013
intracellular mrna localizationGO:000829810.013
positive regulation of translationGO:004572710.013
regulation of protein targetingGO:190353320.013
ventricular cardiac muscle tissue morphogenesisGO:005501020.013
cellular response to lipopolysaccharideGO:007122230.013
heart loopingGO:0001947940.013
epithelial tube morphogenesisGO:00605621480.013
negative regulation of kinase activityGO:003367340.013
regulation of wnt signaling pathwayGO:0030111530.013
cell matrix adhesionGO:000716040.013
embryonic eye morphogenesisGO:0048048300.013
negative regulation of epithelial cell proliferationGO:005068010.013
positive regulation of catabolic processGO:000989640.013
cellular response to endogenous stimulusGO:0071495680.013
zymogen activationGO:003163830.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
Human
calcium ion transport into cytosolGO:006040230.013
protein homooligomerizationGO:005126030.012
Rat
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
calcium mediated signalingGO:001972220.012
positive regulation of cytoskeleton organizationGO:005149530.012
wnt signaling pathwayGO:0016055800.012
positive regulation of metabolic processGO:00098931080.012
Human
atrial cardiac myofibril assemblyGO:005500420.012
endochondral bone morphogenesisGO:006035080.012
forebrain developmentGO:0030900960.012
positive regulation of macromolecule biosynthetic processGO:0010557590.012
adult behaviorGO:003053420.012
response to endogenous stimulusGO:0009719830.012
positive regulation of stress activated mapk cascadeGO:003287430.012
regulation of erk1 and erk2 cascadeGO:007037240.012
cellular response to oxygen containing compoundGO:1901701200.012
regulation of growthGO:0040008420.012
regulation of protein bindingGO:004339330.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
peptidyl serine modificationGO:001820920.012
appendage morphogenesisGO:0035107560.012
negative regulation of protein kinase activityGO:000646940.012
negative regulation of behaviorGO:004852160.012
cell deathGO:00082191210.012
regulation of embryonic developmentGO:0045995470.012
single organism organelle organizationGO:19025891990.012
positive regulation of signalingGO:0023056560.012
regulation of cellular ketone metabolic processGO:001056570.012
phagocytosis engulfmentGO:000691110.012
determination of dorsal ventral asymmetryGO:0048262340.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.011
regulation of canonical wnt signaling pathwayGO:0060828340.011
single organism metabolic processGO:00447102170.011
collagen biosynthetic processGO:003296420.011
regulation of cellular protein metabolic processGO:0032268520.011
Human
proteolysisGO:0006508380.011
neurological system processGO:0050877620.011
epithelial to mesenchymal transitionGO:0001837210.011
deathGO:00162651210.011
regulation of mesenchymal cell proliferationGO:001046410.011
response to alcoholGO:0097305140.011
g1 s transition of mitotic cell cycleGO:000008210.011
anterior posterior pattern specificationGO:00099521520.011
regulation of meiotic cell cycleGO:005144510.011
positive regulation of jnk cascadeGO:004633030.011
hard palate developmentGO:006002240.011
trabecula morphogenesisGO:006138320.011
regulation of protein import into nucleusGO:004230620.011
regulation of cell migrationGO:0030334400.011
Human
gland developmentGO:00487321430.011
endoderm formationGO:0001706290.011
positive regulation of lipid metabolic processGO:004583410.011
small molecule metabolic processGO:0044281770.011
regulation of bindingGO:005109830.011
oxoacid metabolic processGO:0043436310.011
negative regulation of chemotaxisGO:005092240.011
cellular response to lipidGO:0071396390.011
negative regulation of translationGO:001714810.011
positive regulation of wound healingGO:009030310.011
ameboidal type cell migrationGO:00016671430.011
negative regulation of multicellular organismal processGO:0051241690.011
Human
positive regulation of cell communicationGO:0010647560.011
neurotransmitter secretionGO:000726920.011
oocyte anterior posterior axis specificationGO:000731440.011
positive regulation of epithelial cell migrationGO:001063420.011
negative regulation of gene expressionGO:0010629650.011
response to mechanical stimulusGO:0009612240.011
spermatid developmentGO:000728620.011
smoothened signaling pathwayGO:0007224300.011
skin developmentGO:0043588540.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
cellular localizationGO:0051641970.011
olfactory lobe developmentGO:002198840.011
ear developmentGO:00435831270.010
cardiac muscle cell developmentGO:0055013200.010
fin morphogenesisGO:0033334530.010
insulin like growth factor receptor signaling pathwayGO:004800940.010
cellular amine metabolic processGO:004410620.010
oocyte maturationGO:000155640.010
regulation of cell motilityGO:2000145460.010
Human
negative regulation of growthGO:0045926100.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.010
regulation of striated muscle tissue developmentGO:001620260.010
brain developmentGO:00074202930.010
neuron projection extensionGO:1990138450.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
mesenchymal cell differentiationGO:0048762870.010
single organism cellular localizationGO:1902580460.010
neurotransmitter transportGO:000683620.010

thbs4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.078
disease of anatomical entityDOID:700.078
nervous system diseaseDOID:86300.018
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
charcot marie tooth disease type 4DOID:005054100.013
neuromuscular diseaseDOID:44000.013
charcot marie tooth diseaseDOID:1059500.013
neuropathyDOID:87000.013
connective tissue diseaseDOID:6500.012
bone diseaseDOID:008000100.012
bone development diseaseDOID:008000600.012
organ system cancerDOID:005068600.010