Danio rerio

0 known processes

hcn4

hyperpolarization activated cyclic nucleotide-gated potassium channel 4

hcn4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.079
maintenance of locationGO:005123540.047
agingGO:000756820.046
positive regulation of transportGO:005105020.040
amine metabolic processGO:000930820.034
sensory perception of chemical stimulusGO:000760630.034
phagocytosisGO:000690930.033
stem cell maintenanceGO:001982740.033
establishment of localizationGO:00512342440.033
regulation of biological qualityGO:00650082630.031
regulation of synapse assemblyGO:005196330.031
cell part morphogenesisGO:00329902460.031
response to external stimulusGO:00096052640.030
positive regulation of cellular component biogenesisGO:004408930.029
positive regulation of cell cycleGO:004578730.029
regulation of synaptic growth at neuromuscular junctionGO:000858210.029
ion transmembrane transportGO:0034220910.028
transportGO:00068102200.028
organonitrogen compound metabolic processGO:1901564740.028
cell morphogenesisGO:00009022890.028
system processGO:00030081850.028
transmembrane transportGO:00550851200.028
actin polymerization or depolymerizationGO:000815420.027
neurotransmitter transportGO:000683620.026
amino acid transportGO:000686520.026
response to chemicalGO:00422213200.026
regulation of cellular amine metabolic processGO:003323800.025
regulation of reproductive processGO:200024140.025
single organism localizationGO:19025782250.025
cellular amine metabolic processGO:004410620.025
regulation of synapse organizationGO:005080730.024
hormone transportGO:000991420.024
regulation of multicellular organismal processGO:00512392770.024
protein localization to nucleusGO:003450430.024
hormone secretionGO:004687920.024
cellular response to external stimulusGO:007149620.024
cell morphogenesis involved in differentiationGO:00009041950.023
muscle structure developmentGO:00610611960.023
single organism metabolic processGO:00447102170.023
endocrine processGO:005088620.022
regulation of hormone secretionGO:004688320.022
cellular component morphogenesisGO:00329893360.022
cognitionGO:005089010.022
regulation of protein transportGO:005122330.022
head developmentGO:00603223030.022
cellular macromolecule metabolic processGO:00442603910.022
regulation of establishment of protein localizationGO:007020140.022
oxoacid metabolic processGO:0043436310.022
small molecule metabolic processGO:0044281770.021
regulation of bindingGO:005109830.021
regulation of muscle contractionGO:000693730.021
neuron differentiationGO:00301823530.021
compound eye developmentGO:004874920.021
cellular component movementGO:00069283350.021
regulation of cytoplasmic transportGO:190364940.021
regulation of multicellular organismal developmentGO:20000262230.021
neuron neuron synaptic transmissionGO:000727010.021
determination of bilateral symmetryGO:00098552040.021
nitrogen compound metabolic processGO:00068073190.021
female gonad developmentGO:000858540.021
cell projection morphogenesisGO:00488582440.021
chemosensory behaviorGO:000763510.021
multicellular organism growthGO:003526440.021
digestive system developmentGO:00551232890.021
meiotic cell cycle processGO:190304630.021
regulation of blood pressureGO:000821710.021
cellular amino acid metabolic processGO:000652070.021
neuron projection developmentGO:00311751800.020
central nervous system developmentGO:00074173870.020
female sex differentiationGO:004666040.020
sequestering of metal ionGO:005123830.020
signal transductionGO:00071654550.020
regulation of cellular amino acid metabolic processGO:000652100.020
immune system processGO:00023762410.020
negative regulation of sequestering of calcium ionGO:005128340.020
positive regulation of biological processGO:00485182530.020
proteolysis involved in cellular protein catabolic processGO:005160330.020
development of primary female sexual characteristicsGO:004654540.020
single organism transportGO:00447652060.020
cellular nitrogen compound metabolic processGO:00346412900.020
stem cell proliferationGO:007208940.020
organic acid metabolic processGO:0006082310.019
cytokinesisGO:000091030.019
negative regulation of protein phosphorylationGO:000193340.019
positive regulation of cellular catabolic processGO:003133130.019
eye developmentGO:00016542770.019
establishment of protein localization to organelleGO:007259440.019
gastrulationGO:00073692080.019
synaptic growth at neuromuscular junctionGO:005112420.019
regionalizationGO:00030022740.019
regulation of response to stimulusGO:00485832690.019
regulation of blood vessel sizeGO:005088020.019
organic substance biosynthetic processGO:19015762890.019
regulation of cellular ketone metabolic processGO:001056570.019
carboxylic acid metabolic processGO:0019752220.019
negative regulation of protein kinase activityGO:000646940.019
regulation of synaptic plasticityGO:004816710.018
adult behaviorGO:003053420.018
regulation of cytokine productionGO:000181730.018
growthGO:00400071740.018
regulation of endocrine processGO:004406020.018
regulation of metal ion transportGO:001095940.018
response to other organismGO:0051707970.018
regulation of protein catabolic processGO:004217610.018
positive regulation of catabolic processGO:000989640.018
cellular ketone metabolic processGO:0042180110.018
modification dependent macromolecule catabolic processGO:004363230.018
sequestering of calcium ionGO:005120830.018
tube morphogenesisGO:00352393490.018
generation of neuronsGO:00486993850.018
gtp metabolic processGO:004603940.018
locomotionGO:00400113130.018
aromatic compound biosynthetic processGO:00194382170.017
nuclear transportGO:005116940.017
gtp catabolic processGO:000618420.017
cell projection organizationGO:00300302840.017
phototransductionGO:000760220.017
striated muscle cell developmentGO:00550021080.017
synaptic vesicle localizationGO:009747910.017
modification dependent protein catabolic processGO:001994130.017
cellular biosynthetic processGO:00442492860.017
single organism nuclear importGO:190259330.017
neurotransmitter secretionGO:000726920.017
regulation of multicellular organism growthGO:004001440.017
guanosine containing compound metabolic processGO:190106840.017
biosynthetic processGO:00090582940.017
cellular response to extracellular stimulusGO:003166820.016
single fertilizationGO:000733830.016
organic cyclic compound biosynthetic processGO:19013622230.016
cellular protein catabolic processGO:004425740.016
positive regulation of cytosolic calcium ion concentrationGO:000720440.016
regulation of ion transmembrane transporter activityGO:003241220.016
negative regulation of kinase activityGO:003367340.016
negative regulation of biological processGO:00485193040.016
vasculature developmentGO:00019442780.016
cellular response to biotic stimulusGO:007121630.016
regulation of protein complex assemblyGO:004325430.016
regulation of metabolic processGO:00192223590.016
protein importGO:001703830.016
regulation of cell activationGO:005086510.016
cellular response to starvationGO:000926710.016
cell migrationGO:00164772370.016
proteasomal protein catabolic processGO:001049820.016
phagocytosis engulfmentGO:000691110.016
localization of cellGO:00516742440.016
neurological system processGO:0050877620.016
morphogenesis of an epitheliumGO:00020093330.016
positive regulation of immune effector processGO:000269930.016
nuclear importGO:005117030.016
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.016
response to carbohydrateGO:000974330.016
peptidyl lysine acetylationGO:001839420.016
regulation of developmental processGO:00507932470.016
cytoplasm organizationGO:000702840.016
regulation of cell communicationGO:00106462320.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
regulation of tube sizeGO:003515020.015
muscle cell developmentGO:00550011150.015
camera type eye developmentGO:00430102220.015
cation transmembrane transportGO:0098655650.015
nucleocytoplasmic transportGO:000691340.015
cellular aromatic compound metabolic processGO:00067252950.015
translational initiationGO:000641330.015
regulation of circadian rhythmGO:004275240.015
sensory organ developmentGO:00074233930.015
ion transportGO:00068111140.015
protein polymerizationGO:005125840.015
regulation of sequestering of calcium ionGO:005128240.015
rna localizationGO:000640340.015
monovalent inorganic cation transportGO:0015672420.015
nucleic acid templated transcriptionGO:00976591810.015
peptide transportGO:001583310.015
regulation of localizationGO:00328791040.015
regulation of nitrogen compound metabolic processGO:00511712510.015
regulation of cellular metabolic processGO:00313233200.015
guanosine containing compound catabolic processGO:190106920.015
heart developmentGO:00075073130.015
negative regulation of catabolic processGO:000989530.015
cellular nitrogen compound biosynthetic processGO:00442712180.015
lipid storageGO:001991510.015
heterocycle metabolic processGO:00464832900.015
positive regulation of cellular amine metabolic processGO:003324000.015
embryonic organ developmentGO:00485683810.015
regulation of cell shapeGO:000836010.015
protein targeting to nucleusGO:004474430.015
response to drugGO:004249330.015
regulation of inflammatory responseGO:005072720.014
cellular response to lipopolysaccharideGO:007122230.014
golgi vesicle transportGO:004819330.014
cell cycle g1 s phase transitionGO:004484310.014
synaptic vesicle transportGO:004848910.014
lipid catabolic processGO:001604240.014
negative regulation of multicellular organismal processGO:0051241690.014
regulation of protein localization to nucleusGO:190018020.014
positive regulation of lymphocyte mediated immunityGO:000270810.014
regulation of macromolecule metabolic processGO:00602553170.014
rna metabolic processGO:00160702190.014
establishment of synaptic vesicle localizationGO:009748010.014
regulation of meiotic cell cycleGO:005144510.014
cellular component disassemblyGO:002241110.014
protein homooligomerizationGO:005126030.014
positive regulation of reproductive processGO:200024320.014
immune system developmentGO:00025201910.014
angiogenesisGO:00015251580.014
secondary metabolic processGO:001974830.014
response to stressGO:00069502630.014
olfactory lobe developmentGO:002198840.014
blood vessel developmentGO:00015682460.014
exocytosisGO:000688710.014
production of molecular mediator of immune responseGO:000244020.014
post embryonic organ developmentGO:004856940.014
negative regulation of protein localization to nucleusGO:190018120.014
positive regulation of cellular processGO:00485222010.014
positive regulation of secretion by cellGO:190353210.014
sensory perception of smellGO:000760820.014
regulation of gene expressionGO:00104682650.014
rna biosynthetic processGO:00327741810.014
leukocyte proliferationGO:007066110.014
regulation of transmembrane transporter activityGO:002289820.014
regulation of primary metabolic processGO:00800903110.014
macromolecular complex disassemblyGO:003298410.014
sensory perceptionGO:0007600390.014
cellular response to nutrient levelsGO:003166920.014
regulation of sodium ion transportGO:000202820.014
nucleobase containing compound metabolic processGO:00061392740.013
mononuclear cell proliferationGO:003294310.013
blood circulationGO:0008015870.013
lens fiber cell morphogenesisGO:007030930.013
regulation of nucleocytoplasmic transportGO:004682220.013
maternal determination of anterior posterior axis embryoGO:000835840.013
single organism organelle organizationGO:19025891990.013
protein complex disassemblyGO:004324110.013
regulation of neurotransmitter secretionGO:004692810.013
protein import into nucleusGO:000660630.013
negative regulation of secretionGO:005104820.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
meiotic chromosome segregationGO:004513230.013
response to nutrientGO:000758430.013
positive regulation of secretionGO:005104710.013
sleepGO:003043110.013
membrane invaginationGO:001032410.013
ribonucleoside monophosphate catabolic processGO:000915840.013
organic cyclic compound metabolic processGO:19013603010.013
release of sequestered calcium ion into cytosolGO:005120930.013
protein secretionGO:000930610.013
cellular carbohydrate metabolic processGO:004426240.013
gene expressionGO:00104672520.013
muscle organ developmentGO:00075171010.013
calcium ion transport into cytosolGO:006040230.013
cellular component biogenesisGO:00440851780.013
regulation of autophagyGO:001050630.013
b cell activationGO:004211320.013
anterior posterior pattern specificationGO:00099521520.013
homeostatic processGO:00425921420.013
cation transportGO:0006812810.013
regulation of cellular biosynthetic processGO:00313262450.013
actin filament polymerizationGO:003004120.013
regulation of nucleotide catabolic processGO:003081120.013
carbohydrate biosynthetic processGO:001605110.013
protein acylationGO:004354330.013
cytoskeleton dependent cytokinesisGO:006164030.013
neuron developmentGO:00486662620.013
inorganic ion transmembrane transportGO:0098660570.013
positive regulation of cell activationGO:005086710.013
regulation of neurotransmitter transportGO:005158810.012
specification of symmetryGO:00097992040.012
regulation of neural precursor cell proliferationGO:200017730.012
autophagyGO:000691440.012
negative regulation of cellular processGO:00485232830.012
positive regulation of blood circulationGO:190352420.012
cell morphogenesis involved in neuron differentiationGO:00486671630.012
ubiquitin dependent protein catabolic processGO:000651130.012
cell motilityGO:00488702440.012
regulation of systemic arterial blood pressureGO:000307310.012
positive regulation of cytoskeleton organizationGO:005149530.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
response to external biotic stimulusGO:0043207970.012
response to biotic stimulusGO:0009607970.012
transcription from rna polymerase ii promoterGO:0006366800.012
actin filament based movementGO:003004810.012
blood vessel morphogenesisGO:00485142160.012
regulation of signalingGO:00230512350.012
internal peptidyl lysine acetylationGO:001839320.012
regulation of dendrite developmentGO:005077330.012
catechol containing compound metabolic processGO:000971220.012
inorganic cation transmembrane transportGO:0098662500.012
protein stabilizationGO:005082120.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
neuromuscular synaptic transmissionGO:000727420.012
intracellular mrna localizationGO:000829810.012
leukocyte mediated cytotoxicityGO:000190910.012
positive regulation of leukocyte mediated cytotoxicityGO:000191210.012
neuroblast proliferationGO:000740520.012
positive regulation of cytokine productionGO:000181920.012
cellular lipid catabolic processGO:004424230.012
positive regulation of chromatin modificationGO:190331010.012
negative regulation of synapse assemblyGO:005196420.012
cytosolic calcium ion transportGO:006040130.012
negative regulation of defense responseGO:003134820.012
mitochondrion organizationGO:000700540.012
regulation of cell differentiationGO:00455951420.012
protein localization to plasma membraneGO:007265910.012
response to organic substanceGO:00100331530.012
organelle organizationGO:00069962270.012
negative regulation of secretion by cellGO:190353120.012
stem cell divisionGO:001714510.012
lymphocyte proliferationGO:004665110.012
positive regulation of protein complex assemblyGO:003133420.012
extrinsic apoptotic signaling pathwayGO:009719130.011
protein acetylationGO:000647320.011
regulation of purine nucleotide catabolic processGO:003312120.011
negative regulation of mapk cascadeGO:004340940.011
brain developmentGO:00074202930.011
small molecule catabolic processGO:004428230.011
sensory perception of painGO:001923310.011
regulation of skeletal muscle tissue developmentGO:004864140.011
segmentationGO:0035282970.011
negative regulation of chromosome organizationGO:200125110.011
regulation of signal transductionGO:00099662250.011
positive regulation of chromosome organizationGO:200125210.011
regulation of cellular protein catabolic processGO:190336210.011
ovulation cycleGO:004269820.011
convergent extensionGO:00600261180.011
digestive tract morphogenesisGO:00485462310.011
regulation of protein polymerizationGO:003227120.011
regulation of biosynthetic processGO:00098892500.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
carbohydrate homeostasisGO:003350010.011
circulatory system processGO:0003013870.011
positive regulation of cell divisionGO:005178120.011
epithelial tube morphogenesisGO:00605621480.011
cellular component assemblyGO:00226071700.011
positive regulation of histone modificationGO:003105810.011
olfactory bulb developmentGO:002177240.011
heterocycle biosynthetic processGO:00181302150.011
hemopoiesisGO:00300971830.011
somitogenesisGO:0001756870.011
regulation of neuronal synaptic plasticityGO:004816810.011
regulation of nucleoside metabolic processGO:000911820.011
dicarboxylic acid transportGO:000683510.011
digestive tract developmentGO:00485652650.011
interspecies interaction between organismsGO:004441940.011
positive regulation of dna metabolic processGO:005105410.011
behaviorGO:0007610740.011
internal protein amino acid acetylationGO:000647520.011
protein metabolic processGO:00195381830.011
regulation of protein complex disassemblyGO:004324410.011
striated muscle tissue developmentGO:00147061100.011
response to monosaccharideGO:003428430.011
cellular response to molecule of bacterial originGO:007121930.011
regulation of extrinsic apoptotic signaling pathwayGO:200123630.011
regulation of production of molecular mediator of immune responseGO:000270010.011
regulation of transporter activityGO:003240920.011
endocrine hormone secretionGO:006098620.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
regulation of protein ubiquitinationGO:003139630.011
detection of chemical stimulusGO:000959340.011
regulation of membrane potentialGO:0042391230.011
cellular amide metabolic processGO:004360340.010
muscle cell differentiationGO:00426921390.010
homeostasis of number of cellsGO:0048872620.010
multi organism processGO:00517041340.010
nucleic acid metabolic processGO:00903042440.010
embryonic heart tube developmentGO:00350501330.010
response to woundingGO:00096111160.010
phosphorus metabolic processGO:00067931090.010
regulation of protein bindingGO:004339330.010
actin filament based processGO:0030029640.010
ventricular cardiac muscle tissue developmentGO:000322930.010
heart loopingGO:0001947940.010
endosomal transportGO:001619720.010
regulation of protein import into nucleusGO:004230620.010
regulation of nucleic acid templated transcriptionGO:19035062130.010
negative regulation of reproductive processGO:200024230.010
neuron projection morphogenesisGO:00488121610.010
synaptic target recognitionGO:000803910.010
regulation of rna biosynthetic processGO:20011412130.010
fertilizationGO:000956630.010
membrane hyperpolarizationGO:006008110.010
sodium ion transportGO:0006814240.010
spermatid differentiationGO:004851520.010
regulation of cellular macromolecule biosynthetic processGO:20001122220.010
vacuolar transportGO:000703420.010
dopamine metabolic processGO:004241720.010
regulation of translational initiationGO:000644610.010
regulation of transcription dna templatedGO:00063552130.010
rna transportGO:005065820.010
positive regulation of nucleoside metabolic processGO:004597910.010
negative regulation of protein transportGO:005122430.010
lens fiber cell developmentGO:007030730.010
g protein coupled receptor signaling pathwayGO:0007186740.010
skeletal muscle tissue developmentGO:0007519670.010
taxisGO:00423301090.010
single organism membrane fusionGO:004480120.010
cellular macromolecule biosynthetic processGO:00346452240.010
spermatid developmentGO:000728620.010
membrane fusionGO:006102520.010
axonogenesisGO:00074091520.010

hcn4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
musculoskeletal system diseaseDOID:1700.017
nervous system diseaseDOID:86300.016
disease of metabolismDOID:001466700.013
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
muscular diseaseDOID:008000000.011
organ system cancerDOID:005068600.010
sensory system diseaseDOID:005015500.010
eye and adnexa diseaseDOID:149200.010