| signal transduction | GO:0007165 | 455 | 0.573 | Worm |
| cellular response to topologically incorrect protein | GO:0035967 | 2 | 0.449 | Worm |
| response to topologically incorrect protein | GO:0035966 | 2 | 0.418 | Worm |
| cellular macromolecule metabolic process | GO:0044260 | 391 | 0.354 | Rat |
| cellular response to unfolded protein | GO:0034620 | 2 | 0.351 | Worm |
| er nucleus signaling pathway | GO:0006984 | 2 | 0.330 | Worm |
| larval development | GO:0002164 | 2 | 0.319 | |
| endoplasmic reticulum unfolded protein response | GO:0030968 | 2 | 0.270 | Worm |
| modification dependent macromolecule catabolic process | GO:0043632 | 3 | 0.251 | |
| response to endoplasmic reticulum stress | GO:0034976 | 6 | 0.245 | Worm |
| response to oxygen containing compound | GO:1901700 | 55 | 0.233 | |
| modification dependent protein catabolic process | GO:0019941 | 3 | 0.207 | |
| cellular protein catabolic process | GO:0044257 | 4 | 0.197 | |
| response to organic substance | GO:0010033 | 153 | 0.192 | Worm |
| sensory organ development | GO:0007423 | 393 | 0.185 | |
| response to stress | GO:0006950 | 263 | 0.185 | Worm |
| response to unfolded protein | GO:0006986 | 2 | 0.182 | Worm |
| response to chemical | GO:0042221 | 320 | 0.179 | Worm |
| aging | GO:0007568 | 2 | 0.172 | |
| establishment of localization | GO:0051234 | 244 | 0.169 | |
| cellular protein metabolic process | GO:0044267 | 129 | 0.151 | Rat |
| locomotion | GO:0040011 | 313 | 0.141 | |
| cellular response to chemical stimulus | GO:0070887 | 157 | 0.130 | Worm |
| cellular component biogenesis | GO:0044085 | 178 | 0.125 | |
| response to biotic stimulus | GO:0009607 | 97 | 0.117 | |
| proteasomal protein catabolic process | GO:0010498 | 2 | 0.105 | |
| cellular response to organic substance | GO:0071310 | 105 | 0.101 | Worm |
| response to abiotic stimulus | GO:0009628 | 122 | 0.101 | |
| maintenance of location | GO:0051235 | 4 | 0.097 | |
| cell death | GO:0008219 | 121 | 0.097 | |
| protein n linked glycosylation | GO:0006487 | 1 | 0.096 | |
| protein metabolic process | GO:0019538 | 183 | 0.090 | Rat |
| cellular response to extracellular stimulus | GO:0031668 | 2 | 0.088 | |
| leukocyte proliferation | GO:0070661 | 1 | 0.076 | |
| cellular component assembly | GO:0022607 | 170 | 0.075 | |
| negative regulation of cellular process | GO:0048523 | 283 | 0.071 | |
| programmed cell death | GO:0012501 | 119 | 0.071 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 3 | 0.067 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 3 | 0.063 | |
| regulation of muscle contraction | GO:0006937 | 3 | 0.062 | |
| regulation of protein transport | GO:0051223 | 3 | 0.060 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 2 | 0.058 | |
| response to temperature stimulus | GO:0009266 | 15 | 0.057 | |
| cell substrate junction assembly | GO:0007044 | 2 | 0.057 | |
| negative regulation of signal transduction | GO:0009968 | 94 | 0.056 | |
| response to heat | GO:0009408 | 6 | 0.056 | |
| regulation of protein ubiquitination | GO:0031396 | 3 | 0.054 | |
| regulation of response to stimulus | GO:0048583 | 269 | 0.054 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 3 | 0.052 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 3 | 0.048 | |
| cell surface receptor signaling pathway | GO:0007166 | 325 | 0.047 | |
| organonitrogen compound metabolic process | GO:1901564 | 74 | 0.047 | |
| lipid storage | GO:0019915 | 1 | 0.047 | |
| regulation of signal transduction | GO:0009966 | 225 | 0.046 | |
| peptide transport | GO:0015833 | 1 | 0.041 | |
| response to alcohol | GO:0097305 | 14 | 0.040 | |
| regulation of signaling | GO:0023051 | 235 | 0.040 | |
| transport | GO:0006810 | 220 | 0.040 | |
| regulation of blood vessel size | GO:0050880 | 2 | 0.039 | |
| cellular response to starvation | GO:0009267 | 1 | 0.039 | |
| single organism localization | GO:1902578 | 225 | 0.038 | |
| stem cell maintenance | GO:0019827 | 4 | 0.037 | |
| inner ear development | GO:0048839 | 126 | 0.037 | |
| negative regulation of cellular catabolic process | GO:0031330 | 3 | 0.035 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 271 | 0.035 | Worm |
| cellular response to nutrient levels | GO:0031669 | 2 | 0.035 | |
| amide transport | GO:0042886 | 12 | 0.035 | |
| regulation of biological quality | GO:0065008 | 263 | 0.034 | |
| response to hypoxia | GO:0001666 | 25 | 0.034 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 1 | 0.033 | |
| positive regulation of transport | GO:0051050 | 2 | 0.033 | |
| positive regulation of secretion by cell | GO:1903532 | 1 | 0.031 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 4 | 0.030 | |
| regulation of nucleoside metabolic process | GO:0009118 | 2 | 0.029 | |
| regulation of nucleotide catabolic process | GO:0030811 | 2 | 0.029 | |
| response to ethanol | GO:0045471 | 6 | 0.028 | |
| regulation of multicellular organismal process | GO:0051239 | 277 | 0.028 | Worm |
| cellular response to external stimulus | GO:0071496 | 2 | 0.028 | |
| membrane lipid metabolic process | GO:0006643 | 10 | 0.028 | |
| regulation of localization | GO:0032879 | 104 | 0.028 | |
| ear development | GO:0043583 | 127 | 0.028 | |
| establishment of protein localization to organelle | GO:0072594 | 4 | 0.028 | |
| system process | GO:0003008 | 185 | 0.028 | |
| membrane lipid biosynthetic process | GO:0046467 | 2 | 0.027 | |
| regulation of cell death | GO:0010941 | 103 | 0.027 | |
| protein import | GO:0017038 | 3 | 0.026 | |
| cellular protein modification process | GO:0006464 | 100 | 0.026 | |
| ameboidal type cell migration | GO:0001667 | 143 | 0.026 | |
| regulation of response to biotic stimulus | GO:0002831 | 2 | 0.025 | |
| gland development | GO:0048732 | 143 | 0.025 | |
| brain development | GO:0007420 | 293 | 0.025 | |
| response to external biotic stimulus | GO:0043207 | 97 | 0.025 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 69 | 0.024 | |
| macromolecule modification | GO:0043412 | 111 | 0.024 | |
| response to endogenous stimulus | GO:0009719 | 83 | 0.024 | |
| multicellular organism growth | GO:0035264 | 4 | 0.024 | Worm |
| positive regulation of catabolic process | GO:0009896 | 4 | 0.024 | |
| regulation of establishment of protein localization | GO:0070201 | 4 | 0.024 | |
| biosynthetic process | GO:0009058 | 294 | 0.024 | |
| exocytosis | GO:0006887 | 1 | 0.023 | |
| cellular response to stress | GO:0033554 | 62 | 0.023 | Worm |
| specification of symmetry | GO:0009799 | 204 | 0.023 | |
| negative regulation of biological process | GO:0048519 | 304 | 0.023 | |
| response to bacterium | GO:0009617 | 58 | 0.023 | |
| negative regulation of cell communication | GO:0010648 | 96 | 0.023 | |
| regulation of multicellular organism growth | GO:0040014 | 4 | 0.022 | Worm |
| multicellular organismal reproductive process | GO:0048609 | 35 | 0.022 | |
| regulation of systemic arterial blood pressure | GO:0003073 | 1 | 0.022 | |
| positive regulation of cytokine production | GO:0001819 | 2 | 0.021 | |
| single organism organelle organization | GO:1902589 | 199 | 0.021 | |
| regulation of gtpase activity | GO:0043087 | 2 | 0.021 | |
| collagen metabolic process | GO:0032963 | 2 | 0.021 | |
| regulation of blood pressure | GO:0008217 | 1 | 0.021 | |
| regulation of cytokine production | GO:0001817 | 3 | 0.021 | |
| regulation of tube size | GO:0035150 | 2 | 0.021 | |
| negative regulation of nucleocytoplasmic transport | GO:0046823 | 2 | 0.021 | |
| amine metabolic process | GO:0009308 | 2 | 0.021 | |
| regulation of cell shape | GO:0008360 | 1 | 0.021 | |
| response to other organism | GO:0051707 | 97 | 0.021 | |
| muscle cell migration | GO:0014812 | 4 | 0.021 | |
| response to oxygen levels | GO:0070482 | 25 | 0.020 | |
| death | GO:0016265 | 121 | 0.020 | |
| gtp metabolic process | GO:0046039 | 4 | 0.020 | |
| apoptotic process | GO:0006915 | 116 | 0.020 | |
| regulation of cytoplasmic transport | GO:1903649 | 4 | 0.020 | |
| head development | GO:0060322 | 303 | 0.020 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 2 | 0.019 | |
| regulation of protein catabolic process | GO:0042176 | 1 | 0.019 | |
| immune system process | GO:0002376 | 241 | 0.019 | |
| cell motility | GO:0048870 | 244 | 0.018 | |
| macromolecule localization | GO:0033036 | 54 | 0.018 | |
| determination of left right symmetry | GO:0007368 | 179 | 0.018 | |
| nucleocytoplasmic transport | GO:0006913 | 4 | 0.018 | |
| response to external stimulus | GO:0009605 | 264 | 0.018 | |
| negative regulation of catabolic process | GO:0009895 | 3 | 0.018 | |
| regulation of cell activation | GO:0050865 | 1 | 0.018 | |
| endodermal digestive tract morphogenesis | GO:0061031 | 2 | 0.018 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 3 | 0.018 | |
| autophagy | GO:0006914 | 4 | 0.018 | |
| response to glucose | GO:0009749 | 3 | 0.017 | |
| response to decreased oxygen levels | GO:0036293 | 25 | 0.017 | |
| response to wounding | GO:0009611 | 116 | 0.017 | |
| protein secretion | GO:0009306 | 1 | 0.017 | |
| positive regulation of secretion | GO:0051047 | 1 | 0.017 | |
| cell aging | GO:0007569 | 2 | 0.017 | |
| cellular biosynthetic process | GO:0044249 | 286 | 0.017 | |
| cellular modified amino acid metabolic process | GO:0006575 | 3 | 0.017 | |
| hepaticobiliary system development | GO:0061008 | 98 | 0.017 | |
| negative regulation of protein phosphorylation | GO:0001933 | 4 | 0.017 | |
| regulation of developmental process | GO:0050793 | 247 | 0.016 | Worm |
| single organism transport | GO:0044765 | 206 | 0.016 | |
| regulation of hormone levels | GO:0010817 | 21 | 0.016 | |
| positive regulation of cellular catabolic process | GO:0031331 | 3 | 0.016 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 2 | 0.016 | |
| female sex differentiation | GO:0046660 | 4 | 0.016 | |
| multi organism process | GO:0051704 | 134 | 0.016 | |
| regulation of binding | GO:0051098 | 3 | 0.016 | |
| cellular response to lipopolysaccharide | GO:0071222 | 3 | 0.016 | |
| nuclear transport | GO:0051169 | 4 | 0.016 | |
| response to drug | GO:0042493 | 3 | 0.016 | |
| cell migration | GO:0016477 | 237 | 0.016 | |
| cell morphogenesis | GO:0000902 | 289 | 0.016 | |
| positive regulation of cell activation | GO:0050867 | 1 | 0.016 | |
| cellular nitrogen compound metabolic process | GO:0034641 | 290 | 0.015 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 4 | 0.015 | |
| tube morphogenesis | GO:0035239 | 349 | 0.015 | |
| regulation of nuclease activity | GO:0032069 | 1 | 0.015 | |
| peptide metabolic process | GO:0006518 | 1 | 0.015 | |
| nitrogen compound metabolic process | GO:0006807 | 319 | 0.015 | |
| ovulation cycle | GO:0042698 | 2 | 0.015 | |
| digestive system development | GO:0055123 | 289 | 0.015 | |
| nuclear import | GO:0051170 | 3 | 0.015 | |
| female gonad development | GO:0008585 | 4 | 0.014 | |
| multicellular organismal macromolecule metabolic process | GO:0044259 | 2 | 0.014 | |
| production of molecular mediator of immune response | GO:0002440 | 2 | 0.014 | |
| nuclear export | GO:0051168 | 1 | 0.014 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 1 | 0.014 | |
| regulation of gtp catabolic process | GO:0033124 | 2 | 0.014 | |
| central nervous system development | GO:0007417 | 387 | 0.014 | |
| regulation of programmed cell death | GO:0043067 | 101 | 0.014 | |
| gtp catabolic process | GO:0006184 | 2 | 0.014 | |
| response to cold | GO:0009409 | 4 | 0.014 | |
| reproduction | GO:0000003 | 40 | 0.014 | Worm |
| organic substance catabolic process | GO:1901575 | 28 | 0.014 | |
| reproductive process | GO:0022414 | 40 | 0.014 | |
| negative regulation of response to stimulus | GO:0048585 | 104 | 0.014 | |
| response to lipid | GO:0033993 | 60 | 0.014 | |
| mononuclear cell proliferation | GO:0032943 | 1 | 0.014 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 93 | 0.014 | |
| regulation of neurotransmitter secretion | GO:0046928 | 1 | 0.013 | |
| cellular amide metabolic process | GO:0043603 | 4 | 0.013 | |
| regulation of molecular function | GO:0065009 | 70 | 0.013 | |
| positive regulation of cytosolic calcium ion concentration | GO:0007204 | 4 | 0.013 | |
| pronephros development | GO:0048793 | 69 | 0.013 | |
| kidney development | GO:0001822 | 92 | 0.013 | |
| very long chain fatty acid metabolic process | GO:0000038 | 4 | 0.013 | |
| pigmentation | GO:0043473 | 85 | 0.013 | |
| regulation of exocytosis | GO:0017157 | 1 | 0.013 | |
| positive regulation of blood circulation | GO:1903524 | 2 | 0.013 | |
| cellular amine metabolic process | GO:0044106 | 2 | 0.013 | |
| lipid digestion | GO:0044241 | 3 | 0.013 | |
| regulation of cell communication | GO:0010646 | 232 | 0.013 | |
| regulation of multicellular organismal development | GO:2000026 | 223 | 0.013 | |
| smooth muscle contraction | GO:0006939 | 2 | 0.013 | |
| reactive nitrogen species metabolic process | GO:2001057 | 0 | 0.013 | |
| sister chromatid cohesion | GO:0007062 | 2 | 0.012 | |
| phagocytosis | GO:0006909 | 3 | 0.012 | |
| protein modification process | GO:0036211 | 100 | 0.012 | |
| cellular catabolic process | GO:0044248 | 27 | 0.012 | |
| cellular response to biotic stimulus | GO:0071216 | 3 | 0.012 | |
| nitric oxide biosynthetic process | GO:0006809 | 2 | 0.012 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 1 | 0.012 | |
| single organism metabolic process | GO:0044710 | 217 | 0.012 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 69 | 0.012 | |
| negative regulation of programmed cell death | GO:0043069 | 58 | 0.012 | |
| proteolysis | GO:0006508 | 38 | 0.012 | |
| organic substance transport | GO:0071702 | 58 | 0.012 | |
| digestive tract development | GO:0048565 | 265 | 0.012 | |
| ovulation cycle process | GO:0022602 | 2 | 0.012 | |
| neurotransmitter transport | GO:0006836 | 2 | 0.012 | |
| organic substance biosynthetic process | GO:1901576 | 289 | 0.012 | |
| homeostatic process | GO:0042592 | 142 | 0.012 | |
| regulation of cyclin dependent protein serine threonine kinase activity | GO:0000079 | 1 | 0.012 | |
| defense response | GO:0006952 | 47 | 0.012 | |
| organelle organization | GO:0006996 | 227 | 0.012 | |
| single organism biosynthetic process | GO:0044711 | 71 | 0.011 | |
| superoxide metabolic process | GO:0006801 | 2 | 0.011 | |
| regulation of protein binding | GO:0043393 | 3 | 0.011 | |
| epithelial tube morphogenesis | GO:0060562 | 148 | 0.011 | |
| axon ensheathment in central nervous system | GO:0032291 | 2 | 0.011 | |
| lymphocyte proliferation | GO:0046651 | 1 | 0.011 | |
| cellular localization | GO:0051641 | 97 | 0.011 | |
| golgi vesicle transport | GO:0048193 | 3 | 0.011 | |
| determination of bilateral symmetry | GO:0009855 | 204 | 0.011 | |
| regulation of inflammatory response | GO:0050727 | 2 | 0.011 | |
| natural killer cell mediated cytotoxicity | GO:0042267 | 1 | 0.011 | |
| protein import into nucleus | GO:0006606 | 3 | 0.011 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 130 | 0.011 | |
| regulation of metabolic process | GO:0019222 | 359 | 0.011 | |
| negative regulation of signaling | GO:0023057 | 96 | 0.011 | |
| liver development | GO:0001889 | 96 | 0.011 | |
| catabolic process | GO:0009056 | 32 | 0.011 | |
| negative regulation of cytoplasmic transport | GO:1903650 | 2 | 0.011 | |
| antimicrobial humoral response | GO:0019730 | 2 | 0.011 | |
| regulation of autophagy | GO:0010506 | 3 | 0.011 | |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 4 | 0.011 | |
| b cell activation | GO:0042113 | 2 | 0.011 | |
| cellular response to oxygen radical | GO:0071450 | 2 | 0.011 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 0 | 0.011 | |
| urogenital system development | GO:0001655 | 97 | 0.011 | |
| negative regulation of chromosome organization | GO:2001251 | 1 | 0.011 | |
| extracellular matrix organization | GO:0030198 | 27 | 0.011 | |
| renal system development | GO:0072001 | 94 | 0.011 | |
| negative regulation of multicellular organismal process | GO:0051241 | 69 | 0.011 | |
| developmental growth | GO:0048589 | 166 | 0.010 | Worm |
| body morphogenesis | GO:0010171 | 16 | 0.010 | |
| regulation of leukocyte mediated immunity | GO:0002703 | 1 | 0.010 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 2 | 0.010 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 0 | 0.010 | |
| guanosine containing compound metabolic process | GO:1901068 | 4 | 0.010 | |
| response to glucocorticoid | GO:0051384 | 1 | 0.010 | |
| skeletal system development | GO:0001501 | 181 | 0.010 | |
| negative regulation of i kappab kinase nf kappab signaling | GO:0043124 | 1 | 0.010 | |
