Danio rerio

18 known processes

sema3e

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E

(Aliases: fj37c11,wu:fj37c11,si:ch211-120m13.2)

sema3e biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
axonal defasciculationGO:000741420.359
regulation of macromolecule biosynthetic processGO:00105562250.294
neuron developmentGO:00486662620.292
regulation of rna metabolic processGO:00512522240.244
positive regulation of biological processGO:00485182530.239
regulation of cellular metabolic processGO:00313233200.232
morphogenesis of a branching structureGO:0001763210.226
Mouse
regulation of gene expressionGO:00104682650.224
mesenchyme developmentGO:00604851270.223
Zebrafish
facial nerve morphogenesisGO:002161010.222
tube morphogenesisGO:00352393490.216
Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.214
specification of symmetryGO:00097992040.211
cell morphogenesisGO:00009022890.207
Mouse
locomotionGO:00400113130.202
Zebrafish
cellular macromolecule metabolic processGO:00442603910.195
negative regulation of axon extension involved in axon guidanceGO:004884310.171
sympathetic nervous system developmentGO:004848530.170
cell morphogenesis involved in neuron differentiationGO:00486671630.165
positive regulation of cellular processGO:00485222010.158
vasculature developmentGO:00019442780.156
organic cyclic compound biosynthetic processGO:19013622230.155
regulation of cellular macromolecule biosynthetic processGO:20001122220.150
regulation of primary metabolic processGO:00800903110.150
negative regulation of cellular processGO:00485232830.143
Mouse
rna metabolic processGO:00160702190.141
positive regulation of signal transductionGO:0009967560.138
embryo development ending in birth or egg hatchingGO:00097922710.136
biosynthetic processGO:00090582940.131
cellular aromatic compound metabolic processGO:00067252950.129
sensory organ developmentGO:00074233930.126
sprouting angiogenesisGO:0002040530.124
embryonic organ developmentGO:00485683810.123
retina development in camera type eyeGO:00600411460.119
cell projection organizationGO:00300302840.113
negative regulation of biological processGO:00485193040.112
Mouse
localization of cellGO:00516742440.111
Zebrafish
heterocycle metabolic processGO:00464832900.110
regulation of multicellular organismal developmentGO:20000262230.106
Mouse
nucleic acid templated transcriptionGO:00976591810.101
axonogenesisGO:00074091520.099
gene expressionGO:00104672520.096
developmental growthGO:00485891660.092
response to chemicalGO:00422213200.092
regulation of developmental processGO:00507932470.092
Mouse
regulation of collateral sprouting in absence of injuryGO:004869640.091
generation of neuronsGO:00486993850.089
macromolecule biosynthetic processGO:00090592270.089
cell motilityGO:00488702440.088
Zebrafish
cellular nitrogen compound biosynthetic processGO:00442712180.086
regulation of biosynthetic processGO:00098892500.085
chemotaxisGO:00069351040.085
morphogenesis of an epitheliumGO:00020093330.084
Mouse
regulation of nitrogen compound metabolic processGO:00511712510.084
digestive tract developmentGO:00485652650.082
regulation of extrinsic apoptotic signaling pathwayGO:200123630.082
aromatic compound biosynthetic processGO:00194382170.081
cellular component movementGO:00069283350.079
Zebrafish
cell projection morphogenesisGO:00488582440.079
organic cyclic compound metabolic processGO:19013603010.078
developmental growth involved in morphogenesisGO:0060560860.077
synaptic growth at neuromuscular junctionGO:005112420.076
autonomic nervous system developmentGO:0048483190.076
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.075
blood vessel morphogenesisGO:00485142160.075
cell part morphogenesisGO:00329902460.073
cell morphogenesis involved in differentiationGO:00009041950.073
negative regulation of chemotaxisGO:005092240.073
nucleic acid metabolic processGO:00903042440.073
neuron projection developmentGO:00311751800.072
regulation of transcription dna templatedGO:00063552130.071
regulation of axon guidanceGO:190266780.069
regulation of synapse assemblyGO:005196330.069
chordate embryonic developmentGO:00430092710.068
regulation of response to stimulusGO:00485832690.068
nitrogen compound metabolic processGO:00068073190.067
outflow tract morphogenesisGO:000315110.065
cellular nitrogen compound metabolic processGO:00346412900.065
neuron projection morphogenesisGO:00488121610.063
negative chemotaxisGO:005091910.062
cellular biosynthetic processGO:00442492860.062
regulation of synapse organizationGO:005080730.061
digestive system developmentGO:00551232890.061
positive regulation of programmed cell deathGO:0043068290.060
determination of dorsal ventral asymmetryGO:0048262340.058
camera type eye developmentGO:00430102220.058
negative regulation of axon guidanceGO:190266810.057
cartilage developmentGO:0051216960.057
positive regulation of response to stimulusGO:0048584800.057
rna biosynthetic processGO:00327741810.057
positive regulation of apoptotic signaling pathwayGO:200123510.056
regulation of multicellular organismal processGO:00512392770.056
Mouse
extrinsic apoptotic signaling pathwayGO:009719130.055
gastrulationGO:00073692080.055
taxisGO:00423301090.055
transcription dna templatedGO:00063511810.053
regulation of macromolecule metabolic processGO:00602553170.053
growthGO:00400071740.050
regulation of localizationGO:00328791040.050
regulation of axon extension involved in axon guidanceGO:004884160.050
positive regulation of epithelial cell proliferationGO:005067910.049
regulation of cellular component movementGO:0051270550.048
facial nerve developmentGO:002156130.048
cellular macromolecule biosynthetic processGO:00346452240.048
regulation of bmp signaling pathwayGO:0030510390.047
ear developmentGO:00435831270.044
regulation of metabolic processGO:00192223590.044
positive regulation of developmental processGO:0051094500.043
neuron projection extension involved in neuron projection guidanceGO:1902284100.043
regulation of cellular biosynthetic processGO:00313262450.043
regulation of nervous system developmentGO:0051960900.043
organic substance biosynthetic processGO:19015762890.043
response to external stimulusGO:00096052640.042
enzyme linked receptor protein signaling pathwayGO:00071671060.042
regulation of synaptic growth at neuromuscular junctionGO:000858210.041
collateral sprouting in absence of injuryGO:004866940.041
cation transmembrane transportGO:0098655650.041
organelle organizationGO:00069962270.041
Mouse
cell migrationGO:00164772370.040
Zebrafish
neuron differentiationGO:00301823530.040
regulation of rna biosynthetic processGO:20011412130.039
nucleobase containing compound biosynthetic processGO:00346542050.039
positive regulation of cell communicationGO:0010647560.039
axon guidanceGO:0007411860.038
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.037
cell differentiation in spinal cordGO:0021515400.036
regionalizationGO:00030022740.036
blood vessel developmentGO:00015682460.036
regulation of nucleobase containing compound metabolic processGO:00192192500.036
determination of bilateral symmetryGO:00098552040.035
single organism organelle organizationGO:19025891990.035
Mouse
eye morphogenesisGO:00485921440.034
appendage developmentGO:0048736800.034
neuron projection extensionGO:1990138450.034
neuroblast proliferationGO:000740520.034
axon developmentGO:00615641660.032
epithelial tube morphogenesisGO:00605621480.032
Mouse
behaviorGO:0007610740.032
embryonic skeletal system developmentGO:0048706970.032
regulation of cell developmentGO:00602841000.032
dorsal ventral pattern formationGO:00099531250.032
heterocycle biosynthetic processGO:00181302150.032
tissue remodelingGO:004877140.031
motor neuron axon guidanceGO:0008045230.031
protein localization to nucleusGO:003450430.031
regulation of programmed cell deathGO:00430671010.031
agingGO:000756820.031
regulation of epithelial cell proliferationGO:005067830.030
diencephalon developmentGO:0021536580.029
stem cell differentiationGO:00488631170.029
Zebrafish
regulation of protein depolymerizationGO:190187910.029
cell substrate adhesionGO:003158940.029
Mouse
urogenital system developmentGO:0001655970.029
trigeminal nerve developmentGO:002155930.029
regulation of ion transmembrane transporter activityGO:003241220.029
eye developmentGO:00016542770.028
regulation of signal transductionGO:00099662250.028
signal transduction in absence of ligandGO:003803410.028
brain developmentGO:00074202930.028
stem cell developmentGO:0048864820.028
Zebrafish
regulation of multicellular organism growthGO:004001440.028
organic acid catabolic processGO:001605430.028
cell surface receptor signaling pathwayGO:00071663250.028
Mouse
nucleoside phosphate biosynthetic processGO:1901293210.028
regulation of nucleotide biosynthetic processGO:0030808150.027
neuron projection guidanceGO:0097485860.027
cell deathGO:00082191210.027
regulation of chemotaxisGO:0050920180.027
microtubule depolymerizationGO:000701910.027
cell fate commitmentGO:0045165990.027
head developmentGO:00603223030.027
apoptotic processGO:00069151160.027
somite developmentGO:0061053960.026
inorganic ion transmembrane transportGO:0098660570.026
cellular component morphogenesisGO:00329893360.026
Mouse
morphogenesis of a branching epitheliumGO:0061138160.026
Mouse
anatomical structure arrangementGO:004853220.025
nucleobase containing compound metabolic processGO:00061392740.025
hair cell differentiationGO:0035315320.025
protein homooligomerizationGO:005126030.025
developmental cell growthGO:0048588520.024
transportGO:00068102200.024
monovalent inorganic cation transportGO:0015672420.024
transcription from rna polymerase ii promoterGO:0006366800.024
signal transductionGO:00071654550.023
Mouse
axon midline choice point recognitionGO:001619940.023
programmed cell deathGO:00125011190.023
synapse organizationGO:0050808210.023
Mouse
central nervous system developmentGO:00074173870.023
transmembrane transportGO:00550851200.023
guanosine containing compound metabolic processGO:190106840.022
multicellular organism growthGO:003526440.022
protein depolymerizationGO:005126110.022
neural crest cell differentiationGO:0014033720.022
Zebrafish
regulation of cell communicationGO:00106462320.021
cellular component assemblyGO:00226071700.021
cellular component disassemblyGO:002241110.021
negative regulation of axon extensionGO:003051770.021
regulation of transporter activityGO:003240920.021
nephron tubule morphogenesisGO:007207810.021
protein metabolic processGO:00195381830.021
skeletal system morphogenesisGO:00487051020.021
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.021
regulation of microtubule cytoskeleton organizationGO:007050730.021
regulation of neuron projection developmentGO:0010975400.021
spinal cord developmentGO:0021510460.021
negative regulation of catabolic processGO:000989530.020
cranial nerve developmentGO:0021545420.020
gtp catabolic processGO:000618420.020
mesenchymal cell developmentGO:0014031780.020
Zebrafish
nucleocytoplasmic transportGO:000691340.020
regulation of biological qualityGO:00650082630.020
Mouse
nuclear transportGO:005116940.020
positive regulation of cell cycleGO:004578730.020
skeletal system developmentGO:00015011810.020
negative regulation of signalingGO:0023057960.019
regulation of blood vessel sizeGO:005088020.019
connective tissue developmentGO:0061448990.019
regulation of microtubule depolymerizationGO:003111410.019
gland developmentGO:00487321430.019
amino acid transportGO:000686520.019
muscle structure developmentGO:00610611960.019
positive regulation of transportGO:005105020.019
regulation of cell migrationGO:0030334400.019
ion homeostasisGO:0050801410.019
establishment of protein localization to organelleGO:007259440.018
preganglionic parasympathetic nervous system developmentGO:002178360.018
cell matrix adhesionGO:000716040.018
Mouse
regulation of anatomical structure morphogenesisGO:00226031300.018
Mouse
establishment of localizationGO:00512342440.018
regulation of growthGO:0040008420.018
ventral spinal cord developmentGO:0021517350.018
female sex differentiationGO:004666040.018
carboxylic acid catabolic processGO:004639530.018
response to organic substanceGO:00100331530.018
negative regulation of nucleobase containing compound metabolic processGO:0045934590.018
single organism membrane fusionGO:004480120.018
regulation of apoptotic processGO:0042981980.018
inner ear developmentGO:00488391260.018
determination of dorsal identityGO:0048263130.017
bmp signaling pathwayGO:0030509520.017
regulation of cellular component organizationGO:0051128860.017
Mouse
endosomal transportGO:001619720.017
nerve developmentGO:0021675450.017
negative regulation of response to stimulusGO:00485851040.017
epiboly involved in gastrulation with mouth forming secondGO:0055113350.017
purine nucleotide biosynthetic processGO:0006164200.017
positive regulation of cytosolic calcium ion concentrationGO:000720440.017
septum transversum developmentGO:000334340.017
macromolecular complex disassemblyGO:003298410.017
positive regulation of epithelial cell differentiationGO:003085820.017
positive regulation of cell deathGO:0010942290.017
regulation of behaviorGO:0050795240.016
positive regulation of macromolecule metabolic processGO:0010604930.016
branchiomotor neuron axon guidanceGO:002178510.016
central nervous system neuron differentiationGO:0021953740.016
response to growth factorGO:0070848390.016
embryonic skeletal system morphogenesisGO:0048704930.016
mesodermal cell migrationGO:0008078120.016
positive regulation of cytoskeleton organizationGO:005149530.016
protein complex disassemblyGO:004324110.016
cellular component biogenesisGO:00440851780.016
positive regulation of multicellular organismal processGO:0051240520.016
lymph vessel developmentGO:0001945270.016
cytoskeleton organizationGO:0007010960.016
Mouse
small molecule metabolic processGO:0044281770.016
immune system developmentGO:00025201910.016
nuclear importGO:005117030.015
forebrain developmentGO:0030900960.015
regulation of tube sizeGO:003515020.015
tissue regenerationGO:0042246740.015
positive regulation of rna metabolic processGO:0051254590.015
regulation of developmental growthGO:0048638380.015
catechol containing compound metabolic processGO:000971220.015
morphogenesis of an epithelial sheetGO:0002011490.015
somitogenesisGO:0001756870.015
lateral line system developmentGO:0048925760.015
positive regulation of blood circulationGO:190352420.015
regulation of anatomical structure sizeGO:0090066330.015
regulation of cytoplasmic transportGO:190364940.015
regulation of protein complex assemblyGO:004325430.014
blastoderm segmentationGO:000735060.014
astrocyte differentiationGO:004870810.014
regulation of signalingGO:00230512350.014
regulation of stem cell differentiationGO:200073640.014
protein import into nucleusGO:000660630.014
nucleotide biosynthetic processGO:0009165210.014
positive regulation of endothelial cell differentiationGO:004560320.014
positive regulation of muscle organ developmentGO:004863610.014
kidney developmentGO:0001822920.014
proepicardium developmentGO:000334240.014
lateral inhibitionGO:004633110.014
regulation of nucleocytoplasmic transportGO:004682220.014
positive regulation of cellular component biogenesisGO:004408930.014
branching morphogenesis of a nerveGO:004875540.013
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.013
neural retina developmentGO:0003407490.013
embryonic appendage morphogenesisGO:0035113300.013
regulation of protein transportGO:005122330.013
phosphorus metabolic processGO:00067931090.013
guanosine containing compound catabolic processGO:190106920.013
cell migration involved in gastrulationGO:0042074790.013
positive regulation of secretionGO:005104710.013
regulation of endothelial cell differentiationGO:004560130.013
regulation of extent of cell growthGO:0061387290.013
mechanoreceptor differentiationGO:0042490370.013
immune system processGO:00023762410.013
epithelial cell differentiationGO:00308551160.013
hypothalamus cell differentiationGO:002197940.013
regulation of neuron differentiationGO:0045664560.013
appendage morphogenesisGO:0035107560.013
regulation of locomotionGO:0040012550.013
regulation of protein complex disassemblyGO:004324410.013
regulation of metal ion transportGO:001095940.013
multi organism processGO:00517041340.013
single organism transportGO:00447652060.013
cellular protein complex disassemblyGO:004362410.012
compound eye developmentGO:004874920.012
positive regulation of cell differentiationGO:0045597300.012
actin polymerization or depolymerizationGO:000815420.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
regulation of protein localization to nucleusGO:190018020.012
spinal cord motor neuron differentiationGO:0021522260.012
cellular protein metabolic processGO:00442671290.012
segment polarity determinationGO:000736710.012
inner ear receptor cell differentiationGO:0060113290.012
small molecule catabolic processGO:004428230.012
golgi organizationGO:000703010.012
positive regulation of neutrophil migrationGO:190262400.012
single organism nuclear importGO:190259330.012
lymphangiogenesisGO:0001946250.012
positive regulation of apoptotic processGO:0043065290.012
regulation of cell projection assemblyGO:006049140.012
response to radiationGO:0009314510.012
ion transmembrane transportGO:0034220910.012
embryonic organ morphogenesisGO:00485622740.012
response to stressGO:00069502630.012
stem cell proliferationGO:007208940.012
single organism metabolic processGO:00447102170.012
heart valve formationGO:000318840.012
liver developmentGO:0001889960.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.012
regulation of transmembrane transporter activityGO:002289820.012
axon extension involved in axon guidanceGO:0048846100.011
cardiac chamber developmentGO:0003205190.011
response to external biotic stimulusGO:0043207970.011
mesoderm developmentGO:0007498880.011
catecholamine metabolic processGO:000658420.011
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082340.011
negative regulation of blood circulationGO:190352320.011
cellular response to chemical stimulusGO:00708871570.011
muscle organ developmentGO:00075171010.011
positive regulation of metabolic processGO:00098931080.011
organelle fusionGO:004828430.011
maternal determination of anterior posterior axis embryoGO:000835840.011
embryonic digestive tract developmentGO:004856640.011
renal system developmentGO:0072001940.011
g protein coupled receptor signaling pathwayGO:0007186740.011
regulation of ion transportGO:0043269220.011
sympathetic ganglion developmentGO:006154920.011
positive regulation of nucleoside metabolic processGO:004597910.011
negative regulation of cell communicationGO:0010648960.011
angiogenesisGO:00015251580.011
organonitrogen compound biosynthetic processGO:1901566470.011
regulation of bone mineralizationGO:003050020.011
proteolysis involved in cellular protein catabolic processGO:005160330.011
deathGO:00162651210.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.010
segmentationGO:0035282970.010
nephron epithelium morphogenesisGO:007208810.010
neurological system processGO:0050877620.010
cardiac chamber morphogenesisGO:0003206120.010
positive regulation of endothelial cell proliferationGO:000193810.010
response to alkaloidGO:004327920.010
glial cell migrationGO:000834730.010
regulation of vasculature developmentGO:1901342330.010
Mouse
regulation of cell matrix adhesionGO:000195210.010
Mouse
positive regulation of catabolic processGO:000989640.010
positive regulation of rna biosynthetic processGO:1902680570.010
maintenance of locationGO:005123540.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.010

sema3e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.062
cardiovascular system diseaseDOID:128700.023
musculoskeletal system diseaseDOID:1700.022
nervous system diseaseDOID:86300.021
bone diseaseDOID:008000100.017
connective tissue diseaseDOID:6500.017
inherited metabolic disorderDOID:65500.014
disease of metabolismDOID:001466700.014
heart diseaseDOID:11400.013