Danio rerio

18 known processes

eif4e

eukaryotic translation initiation factor 4e

(Aliases: eif4e-1,zgc:86680,eif4e1a)

eif4e biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.426
deathGO:00162651210.384
establishment of localizationGO:00512342440.367
immune system processGO:00023762410.319
apoptotic processGO:00069151160.275
regulation of mrna processingGO:005068430.243
biosynthetic processGO:00090582940.229
immune system developmentGO:00025201910.194
hemopoiesisGO:00300971830.193
programmed cell deathGO:00125011190.189
positive regulation of metabolic processGO:00098931080.185
regulation of apoptotic processGO:0042981980.180
meiotic chromosome segregationGO:004513230.179
cellular nitrogen compound metabolic processGO:00346412900.179
regulation of metabolic processGO:00192223590.173
organic substance biosynthetic processGO:19015762890.158
cellular amine metabolic processGO:004410620.158
cell deathGO:00082191210.157
hematopoietic or lymphoid organ developmentGO:00485341910.153
positive regulation of biological processGO:00485182530.152
nuclear transportGO:005116940.132
amine metabolic processGO:000930820.120
regulation of programmed cell deathGO:00430671010.117
organonitrogen compound metabolic processGO:1901564740.110
purine nucleoside monophosphate catabolic processGO:000912840.103
cellular component assemblyGO:00226071700.102
embryo development ending in birth or egg hatchingGO:00097922710.097
cellular component biogenesisGO:00440851780.097
macromolecule biosynthetic processGO:00090592270.096
regulation of macromolecule metabolic processGO:00602553170.091
regulation of cellular macromolecule biosynthetic processGO:20001122220.090
nucleocytoplasmic transportGO:000691340.088
modification dependent macromolecule catabolic processGO:004363230.087
cell cycleGO:0007049930.085
alternative mrna splicing via spliceosomeGO:000038010.081
muscle cell differentiationGO:00426921390.080
positive regulation of cellular catabolic processGO:003133130.079
digestive system developmentGO:00551232890.077
regulation of cellular biosynthetic processGO:00313262450.077
regulation of cell deathGO:00109411030.076
cellular component movementGO:00069283350.074
agingGO:000756820.073
positive regulation of cellular processGO:00485222010.072
establishment of protein localization to organelleGO:007259440.071
cellular macromolecule biosynthetic processGO:00346452240.068
hematopoietic progenitor cell differentiationGO:0002244230.067
positive regulation of cellular metabolic processGO:0031325940.067
protein importGO:001703830.065
single organism localizationGO:19025782250.064
myeloid cell differentiationGO:0030099860.064
regulation of cellular metabolic processGO:00313233200.063
ubiquitin dependent protein catabolic processGO:000651130.063
regulation of reproductive processGO:200024140.063
transportGO:00068102200.063
regulation of multicellular organism growthGO:004001440.062
regulation of cell differentiationGO:00455951420.062
regulation of establishment of protein localizationGO:007020140.062
cell motilityGO:00488702440.062
morphogenesis of an epitheliumGO:00020093330.061
mrna splicing via spliceosomeGO:0000398100.061
heterocycle metabolic processGO:00464832900.060
stem cell proliferationGO:007208940.059
multicellular organism growthGO:003526440.059
cellular response to dna damage stimulusGO:0006974240.058
guanosine containing compound catabolic processGO:190106920.058
regionalizationGO:00030022740.056
regulation of cell shapeGO:000836010.056
regulation of developmental processGO:00507932470.056
heterocycle biosynthetic processGO:00181302150.056
fertilizationGO:000956630.055
embryonic organ developmentGO:00485683810.055
mitochondrion organizationGO:000700540.054
regulation of nitrogen compound metabolic processGO:00511712510.054
intracellular signal transductionGO:0035556850.052
regulation of gene expressionGO:00104682650.052
cellular macromolecule metabolic processGO:00442603910.051
stem cell maintenanceGO:001982740.050
leukocyte proliferationGO:007066110.049
cellular biosynthetic processGO:00442492860.047
digestive tract developmentGO:00485652650.047
gastrulationGO:00073692080.047
regulation of rna biosynthetic processGO:20011412130.047
negative regulation of programmed cell deathGO:0043069580.047
regulation of rna metabolic processGO:00512522240.046
nitrogen compound metabolic processGO:00068073190.046
regulation of primary metabolic processGO:00800903110.045
regulation of multicellular organismal developmentGO:20000262230.045
organic cyclic compound metabolic processGO:19013603010.044
regulation of cytoplasmic transportGO:190364940.044
organonitrogen compound biosynthetic processGO:1901566470.044
nuclear importGO:005117030.043
guanosine containing compound metabolic processGO:190106840.043
positive regulation of transportGO:005105020.043
proteolysis involved in cellular protein catabolic processGO:005160330.042
cell migrationGO:00164772370.041
negative regulation of cellular processGO:00485232830.041
protein targeting to nucleusGO:004474430.041
regulation of signal transductionGO:00099662250.040
dna catabolic processGO:000630810.040
regulation of multicellular organismal processGO:00512392770.040
b cell differentiationGO:003018310.039
embryonic organ morphogenesisGO:00485622740.039
protein localization to nucleusGO:003450430.039
embryonic limb morphogenesisGO:003032620.038
localization of cellGO:00516742440.038
cell morphogenesisGO:00009022890.038
generation of neuronsGO:00486993850.038
rna metabolic processGO:00160702190.037
single organism transportGO:00447652060.036
cellular aromatic compound metabolic processGO:00067252950.036
cellular response to chemical stimulusGO:00708871570.036
cell proliferationGO:0008283800.036
b cell activationGO:004211320.036
regulation of cellular amine metabolic processGO:003323800.036
regulation of mitochondrion organizationGO:001082110.036
digestive tract morphogenesisGO:00485462310.035
single organism metabolic processGO:00447102170.035
purine ribonucleoside monophosphate catabolic processGO:000916940.035
blood vessel developmentGO:00015682460.035
positive regulation of catalytic activityGO:0043085250.034
cellular protein metabolic processGO:00442671290.034
regulation of alternative mrna splicing via spliceosomeGO:000038110.034
mononuclear cell proliferationGO:003294310.034
organelle assemblyGO:00709251100.034
establishment of localization in cellGO:0051649770.034
spindle assemblyGO:005122520.033
regulation of catalytic activityGO:0050790550.033
cytoskeleton organizationGO:0007010960.032
signal transductionGO:00071654550.032
positive regulation of response to stimulusGO:0048584800.031
regulation of skeletal muscle tissue developmentGO:004864140.031
cellular macromolecular complex assemblyGO:0034622240.030
positive regulation of purine nucleotide catabolic processGO:003312310.030
taxisGO:00423301090.029
embryonic pattern specificationGO:0009880440.029
meiotic cell cycle processGO:190304630.029
single organism nuclear importGO:190259330.029
phosphorus metabolic processGO:00067931090.029
rna biosynthetic processGO:00327741810.028
negative regulation of cell deathGO:0060548600.028
response to monosaccharideGO:003428430.028
regulation of protein ubiquitinationGO:003139630.028
nucleobase containing compound metabolic processGO:00061392740.028
neuron differentiationGO:00301823530.027
cellular ketone metabolic processGO:0042180110.027
cellular localizationGO:0051641970.027
oxoacid metabolic processGO:0043436310.027
tube morphogenesisGO:00352393490.027
atp catabolic processGO:000620040.027
positive regulation of catabolic processGO:000989640.027
positive regulation of dna metabolic processGO:005105410.026
positive regulation of cell cycleGO:004578730.026
vasculature developmentGO:00019442780.026
rna splicingGO:0008380160.026
regulation of intracellular protein transportGO:003315730.026
ribonucleoside monophosphate catabolic processGO:000915840.026
microtubule organizing center organizationGO:003102310.025
negative regulation of apoptotic processGO:0043066550.025
regulation of neuron differentiationGO:0045664560.025
nucleic acid metabolic processGO:00903042440.024
nucleic acid templated transcriptionGO:00976591810.024
single fertilizationGO:000733830.024
small molecule metabolic processGO:0044281770.024
regulation of response to stimulusGO:00485832690.024
nuclear exportGO:005116810.024
cytokinesisGO:000091030.023
regulation of nucleoside metabolic processGO:000911820.023
cellular protein catabolic processGO:004425740.023
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.023
response to stressGO:00069502630.022
macromolecular complex assemblyGO:0065003350.022
cellular component morphogenesisGO:00329893360.022
aromatic compound biosynthetic processGO:00194382170.022
lymphocyte proliferationGO:004665110.022
embryonic digestive tract developmentGO:004856640.022
catecholamine metabolic processGO:000658420.022
axis specificationGO:0009798430.022
nucleobase containing compound biosynthetic processGO:00346542050.022
neuron projection morphogenesisGO:00488121610.022
microtubule cytoskeleton organization involved in mitosisGO:190285010.022
cell morphogenesis involved in neuron differentiationGO:00486671630.022
regulation of anatomical structure morphogenesisGO:00226031300.022
axon developmentGO:00615641660.021
single organism cellular localizationGO:1902580460.021
centrosome cycleGO:000709810.021
gene expressionGO:00104672520.021
organic acid metabolic processGO:0006082310.021
regulation of cell developmentGO:00602841000.021
regulation of nucleocytoplasmic transportGO:004682220.021
phagocytosisGO:000690930.021
regulation of macromolecule biosynthetic processGO:00105562250.021
regulation of cellular amino acid metabolic processGO:000652100.021
protein import into nucleusGO:000660630.021
negative regulation of cytoplasmic transportGO:190365020.021
protein metabolic processGO:00195381830.021
protein polyubiquitinationGO:000020940.021
heart developmentGO:00075073130.021
nucleobase containing compound catabolic processGO:0034655150.021
regulation of nucleic acid templated transcriptionGO:19035062130.021
proteasomal protein catabolic processGO:001049820.020
gtp catabolic processGO:000618420.020
positive regulation of macromolecule metabolic processGO:0010604930.020
maintenance of locationGO:005123540.020
negative regulation of autophagyGO:001050710.020
regulation of cellular ketone metabolic processGO:001056570.020
dorsal ventral pattern formationGO:00099531250.020
regulation of growthGO:0040008420.019
positive regulation of cellular amine metabolic processGO:003324000.019
regulation of neurogenesisGO:0050767870.019
anterior posterior pattern specificationGO:00099521520.019
regulation of i kappab kinase nf kappab signalingGO:004312240.019
single organism organelle organizationGO:19025891990.019
chordate embryonic developmentGO:00430092710.019
translational initiationGO:000641330.019
cell surface receptor signaling pathwayGO:00071663250.019
positive regulation of nucleobase containing compound metabolic processGO:0045935690.019
reproductionGO:0000003400.019
regulation of mitotic cell cycleGO:0007346250.018
organic cyclic compound biosynthetic processGO:19013622230.018
stem cell differentiationGO:00488631170.018
response to chemicalGO:00422213200.018
cellular amino acid metabolic processGO:000652070.018
stem cell fate commitmentGO:004886510.018
positive regulation of nucleotide catabolic processGO:003081310.018
regulation of extrinsic apoptotic signaling pathwayGO:200123630.018
gland developmentGO:00487321430.018
regulation of nucleobase containing compound metabolic processGO:00192192500.018
cellular nitrogen compound biosynthetic processGO:00442712180.018
segmentationGO:0035282970.018
response to external stimulusGO:00096052640.017
negative regulation of biological processGO:00485193040.017
double strand break repairGO:000630230.017
modification dependent protein catabolic processGO:001994130.017
regulation of biological qualityGO:00650082630.017
gtp metabolic processGO:004603940.017
regulation of synapse organizationGO:005080730.016
vitamin biosynthetic processGO:000911020.016
stem cell divisionGO:001714510.016
striated muscle cell differentiationGO:00511461290.016
regulation of rna splicingGO:004348480.016
somitogenesisGO:0001756870.016
spermatid differentiationGO:004851520.016
neuron developmentGO:00486662620.016
protein complex assemblyGO:0006461300.016
protein complex biogenesisGO:0070271300.016
negative regulation of developmental processGO:0051093650.016
response to uvGO:000941130.016
neuroblast proliferationGO:000740520.016
regulation of mrna splicing via spliceosomeGO:004802430.016
pronuclear migrationGO:003504610.016
regulation of bindingGO:005109830.016
somite developmentGO:0061053960.016
regulation of cell activationGO:005086510.016
regulation of biosynthetic processGO:00098892500.015
mitotic dna damage checkpointGO:004477340.015
establishment of organelle localizationGO:0051656450.015
negative regulation of axon extension involved in axon guidanceGO:004884310.015
regulation of organelle assemblyGO:190211540.015
actin filament polymerizationGO:003004120.015
macromolecule localizationGO:0033036540.015
transcription dna templatedGO:00063511810.015
regulation of cellular response to stressGO:0080135200.015
nucleoside monophosphate catabolic processGO:000912540.015
positive regulation of i kappab kinase nf kappab signalingGO:004312330.015
cell projection morphogenesisGO:00488582440.015
positive regulation of translationGO:004572710.015
macromolecular complex subunit organizationGO:0043933740.015
sensory perception of chemical stimulusGO:000760630.015
negative regulation of intracellular transportGO:003238730.014
single organism reproductive processGO:0044702400.014
oocyte anterior posterior axis specificationGO:000731440.014
cell cycle processGO:0022402530.014
regulation of protein metabolic processGO:0051246560.014
convergent extensionGO:00600261180.014
cell projection organizationGO:00300302840.014
muscle structure developmentGO:00610611960.014
organelle fusionGO:004828430.014
positive regulation of jnk cascadeGO:004633030.014
regulation of signal transduction by p53 class mediatorGO:190179690.014
axonogenesisGO:00074091520.014
extrinsic apoptotic signaling pathwayGO:009719130.014
regulation of signalingGO:00230512350.014
cellular response to light stimulusGO:007148240.014
positive regulation of developmental processGO:0051094500.013
positive regulation of cell activationGO:005086710.013
insulin like growth factor receptor signaling pathwayGO:004800940.013
regulation of cell communicationGO:00106462320.013
morphogenesis of an epithelial sheetGO:0002011490.013
negative regulation of protein kinase activityGO:000646940.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
response to carbohydrateGO:000974330.013
regulation of cellular protein metabolic processGO:0032268520.013
positive regulation of cellular component biogenesisGO:004408930.013
regulation of translational initiationGO:000644610.013
centrosome organizationGO:005129710.013
apoptotic signaling pathwayGO:0097190230.012
photoreceptor cell morphogenesisGO:000859410.012
regulation of molecular functionGO:0065009700.012
negative regulation of signalingGO:0023057960.012
regulation of nucleotide catabolic processGO:003081120.012
response to amphetamineGO:000197510.012
organic substance catabolic processGO:1901575280.012
regulation of intracellular signal transductionGO:1902531570.012
cell cycle g1 s phase transitionGO:004484310.012
cellular response to stressGO:0033554620.012
cell fate specificationGO:0001708680.012
reproductive processGO:0022414400.012
g1 s transition of mitotic cell cycleGO:000008210.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.012
double strand break repair via homologous recombinationGO:000072410.012
mitochondrial transportGO:000683920.012
determination of bilateral symmetryGO:00098552040.012
negative regulation of protein transportGO:005122430.012
cellular component assembly involved in morphogenesisGO:00109271070.012
cellular response to extracellular stimulusGO:003166820.012
cellular amide metabolic processGO:004360340.012
carboxylic acid metabolic processGO:0019752220.012
negative regulation of intracellular protein transportGO:009031730.012
regulation of tube sizeGO:003515020.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
response to external biotic stimulusGO:0043207970.011
negative regulation of signal transductionGO:0009968940.011
mechanosensory behaviorGO:000763820.011
cell growthGO:0016049570.011
positive regulation of signal transductionGO:0009967560.011
regulation of protein catabolic processGO:004217610.011
erk1 and erk2 cascadeGO:007037140.011
organelle organizationGO:00069962270.011
fat soluble vitamin metabolic processGO:000677540.011
signal transduction by p53 class mediatorGO:0072331130.011
g2 m transition of mitotic cell cycleGO:000008640.011
neuron projection developmentGO:00311751800.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
regulation of cellular component sizeGO:0032535300.011
muscle tissue developmentGO:00605371100.011
regulation of protein transportGO:005122330.011
microtubule based processGO:0007017600.011
recombinational repairGO:000072510.011
cytoplasmic transportGO:0016482110.011
developmental growthGO:00485891660.010
cytoplasm organizationGO:000702840.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.010
ion transportGO:00068111140.010
oocyte maturationGO:000155640.010
response to organic substanceGO:00100331530.010
mitotic dna integrity checkpointGO:004477440.010
specification of symmetryGO:00097992040.010
negative regulation of i kappab kinase nf kappab signalingGO:004312410.010
protein complex subunit organizationGO:0071822460.010
positive regulation of cell differentiationGO:0045597300.010
positive regulation of multi organism processGO:004390230.010
macromolecule modificationGO:00434121110.010
dopamine metabolic processGO:004241720.010
regulation of oocyte developmentGO:006028130.010
response to glucoseGO:000974930.010

eif4e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.027
disease of anatomical entityDOID:700.027
organ system cancerDOID:005068600.018
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.018