Danio rerio

69 known processes

nkx2.7

NK2 transcription factor related 7

(Aliases: zgc:100762,MGC100762,nk2.7,nkx2-7)

nkx2.7 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic organ morphogenesisGO:00485622740.816
neuron developmentGO:00486662620.724
Zebrafish
aromatic compound biosynthetic processGO:00194382170.542
Worm
camera type eye developmentGO:00430102220.535
organic substance biosynthetic processGO:19015762890.494
Worm
embryonic organ developmentGO:00485683810.477
cellular component movementGO:00069283350.448
Zebrafish
cellular biosynthetic processGO:00442492860.407
Worm
organic cyclic compound metabolic processGO:19013603010.382
Worm
cell migrationGO:00164772370.359
Zebrafish
nucleobase containing compound metabolic processGO:00061392740.346
Worm
cellular component biogenesisGO:00440851780.342
heart developmentGO:00075073130.340
sensory organ morphogenesisGO:00905962000.339
regulation of cellular metabolic processGO:00313233200.330
Worm
embryonic hemopoiesisGO:0035162530.329
neuron differentiationGO:00301823530.310
Zebrafish
regulation of developmental processGO:00507932470.308
regulation of cell differentiationGO:00455951420.300
cellular aromatic compound metabolic processGO:00067252950.272
Worm
sensory organ developmentGO:00074233930.270
organelle organizationGO:00069962270.259
endocrine system developmentGO:0035270650.247
Zebrafish
cellular component assemblyGO:00226071700.239
heterocycle metabolic processGO:00464832900.238
Worm
eye developmentGO:00016542770.204
tube morphogenesisGO:00352393490.200
cellular macromolecule metabolic processGO:00442603910.200
Worm
retina development in camera type eyeGO:00600411460.191
chordate embryonic developmentGO:00430092710.189
Zebrafish
cellular nitrogen compound biosynthetic processGO:00442712180.186
Worm
positive regulation of epithelial cell differentiationGO:003085820.180
heart morphogenesisGO:00030071560.179
gene expressionGO:00104672520.178
Worm
nitrogen compound metabolic processGO:00068073190.177
Worm
muscle structure developmentGO:00610611960.177
cellular nitrogen compound metabolic processGO:00346412900.176
Worm
heterocycle biosynthetic processGO:00181302150.175
Worm
cell fate specificationGO:0001708680.174
Zebrafish
embryonic skeletal system morphogenesisGO:0048704930.173
regulation of nucleobase containing compound metabolic processGO:00192192500.170
Worm
regulation of biological qualityGO:00650082630.168
single organism metabolic processGO:00447102170.165
cell fate commitmentGO:0045165990.161
Zebrafish
organ formationGO:0048645170.158
generation of neuronsGO:00486993850.155
Zebrafish
transcription dna templatedGO:00063511810.151
Worm
cardiac atrium morphogenesisGO:000320920.148
cardiac chamber formationGO:000320740.148
muscle tissue developmentGO:00605371100.140
regulation of macromolecule metabolic processGO:00602553170.139
Worm
stem cell maintenanceGO:001982740.139
regulation of nitrogen compound metabolic processGO:00511712510.136
Worm
embryo development ending in birth or egg hatchingGO:00097922710.135
Zebrafish
regulation of rna metabolic processGO:00512522240.132
Worm
embryonic skeletal system developmentGO:0048706970.129
localization of cellGO:00516742440.129
Zebrafish
signal transductionGO:00071654550.124
eye morphogenesisGO:00485921440.119
pancreas developmentGO:0031016840.117
Zebrafish
regulation of multicellular organismal processGO:00512392770.116
central nervous system developmentGO:00074173870.114
Zebrafish
cardiac atrium developmentGO:000323040.114
appendage developmentGO:0048736800.113
microtubule based processGO:0007017600.110
cognitionGO:005089010.110
regulation of transcription dna templatedGO:00063552130.105
Worm
digestive tract morphogenesisGO:00485462310.102
positive regulation of metabolic processGO:00098931080.102
Worm
negative regulation of developmental processGO:0051093650.101
morphogenesis of an epitheliumGO:00020093330.100
macromolecule biosynthetic processGO:00090592270.098
Worm
brain developmentGO:00074202930.097
nucleic acid metabolic processGO:00903042440.096
Worm
lipid storageGO:001991510.092
regulation of rna biosynthetic processGO:20011412130.091
Worm
regulation of biosynthetic processGO:00098892500.089
Worm
regulation of retina development in camera type eyeGO:190286620.088
larval developmentGO:000216420.088
regulation of cellular biosynthetic processGO:00313262450.087
Worm
single organism organelle organizationGO:19025891990.087
regulation of epithelial cell proliferationGO:005067830.086
gastrulationGO:00073692080.085
positive regulation of biosynthetic processGO:0009891680.084
Worm
cell projection organizationGO:00300302840.083
Zebrafish
multicellular organism growthGO:003526440.082
regulation of neural retina developmentGO:006107420.082
cell projection morphogenesisGO:00488582440.081
Zebrafish
head developmentGO:00603223030.081
transcription from rna polymerase ii promoterGO:0006366800.081
Worm
synaptic growth at neuromuscular junctionGO:005112420.078
cardiogenic plate morphogenesisGO:000314210.077
peripheral nervous system neuron developmentGO:0048935220.076
system processGO:00030081850.076
regulation of metabolic processGO:00192223590.076
Worm
regulation of apoptotic processGO:0042981980.075
skeletal system developmentGO:00015011810.073
cellular component morphogenesisGO:00329893360.073
Zebrafish
fin developmentGO:0033333770.072
embryonic cranial skeleton morphogenesisGO:0048701900.072
regulation of neurogenesisGO:0050767870.070
cardiocyte differentiationGO:0035051440.070
stem cell proliferationGO:007208940.070
digestive tract developmentGO:00485652650.069
Worm
mechanosensory lateral line system developmentGO:0048881490.067
regulation of macromolecule biosynthetic processGO:00105562250.066
Worm
positive regulation of nitrogen compound metabolic processGO:0051173690.066
Worm
ameboidal type cell migrationGO:00016671430.066
determination of heart left right asymmetryGO:00613711170.066
nucleobase containing compound biosynthetic processGO:00346542050.065
Worm
muscle organ developmentGO:00075171010.064
Worm
cellular component assembly involved in morphogenesisGO:00109271070.063
rna metabolic processGO:00160702190.062
Worm
vasculature developmentGO:00019442780.062
regulation of response to stimulusGO:00485832690.059
specification of organ identityGO:001009220.058
cellular localizationGO:0051641970.058
renal system developmentGO:0072001940.055
developmental growthGO:00485891660.055
positive regulation of stem cell proliferationGO:200064810.055
cell proliferationGO:0008283800.055
cardiac chamber developmentGO:0003205190.051
regulation of gene expressionGO:00104682650.051
Worm
regulation of multicellular organismal developmentGO:20000262230.051
negative regulation of cell differentiationGO:0045596460.050
retina morphogenesis in camera type eyeGO:0060042790.049
blood vessel developmentGO:00015682460.049
negative regulation of cellular processGO:00485232830.048
ribonucleoside monophosphate catabolic processGO:000915840.048
mesenchyme developmentGO:00604851270.048
positive regulation of transcription dna templatedGO:0045893570.048
Worm
forebrain developmentGO:0030900960.047
left right pattern formationGO:0060972190.047
retina layer formationGO:0010842240.046
peripheral nervous system neuron differentiationGO:0048934280.046
inner ear receptor cell fate commitmentGO:006012040.045
myeloid cell developmentGO:0061515320.045
locomotionGO:00400113130.045
Zebrafish
response to stressGO:00069502630.044
immune system developmentGO:00025201910.044
stem cell differentiationGO:00488631170.044
striated muscle cell differentiationGO:00511461290.044
cell part morphogenesisGO:00329902460.044
Zebrafish
biosynthetic processGO:00090582940.044
Worm
positive regulation of macromolecule biosynthetic processGO:0010557590.044
Worm
hemopoiesisGO:00300971830.043
embryonic heart tube developmentGO:00350501330.043
axon developmentGO:00615641660.043
Zebrafish
adult behaviorGO:003053420.043
specification of symmetryGO:00097992040.043
camera type eye morphogenesisGO:00485931080.041
neural retina developmentGO:0003407490.041
regulation of neuron differentiationGO:0045664560.041
response to mechanical stimulusGO:0009612240.041
muscle cell differentiationGO:00426921390.040
digestive system developmentGO:00551232890.040
Worm
adenohypophysis developmentGO:0021984150.040
locomotory behaviorGO:0007626340.039
negative regulation of macromolecule metabolic processGO:0010605760.038
nucleic acid templated transcriptionGO:00976591810.037
Worm
protein complex subunit organizationGO:0071822460.037
neuron projection developmentGO:00311751800.037
Zebrafish
regulation of cell cycleGO:0051726520.037
negative regulation of biological processGO:00485193040.037
establishment of localizationGO:00512342440.036
Worm
homeostatic processGO:00425921420.035
organic cyclic compound biosynthetic processGO:19013622230.035
Worm
determination of left right symmetryGO:00073681790.034
regulation of cell developmentGO:00602841000.034
positive regulation of cellular processGO:00485222010.034
Worm
glial cell migrationGO:000834730.034
Zebrafish
compound eye developmentGO:004874920.033
regulation of cellular macromolecule biosynthetic processGO:20001122220.033
Worm
positive regulation of biological processGO:00485182530.033
Worm
agingGO:000756820.033
small molecule metabolic processGO:0044281770.033
maintenance of locationGO:005123540.033
eye photoreceptor cell differentiationGO:0001754450.032
establishment of localization in cellGO:0051649770.032
nerve developmentGO:0021675450.032
positive regulation of cellular biosynthetic processGO:0031328680.031
Worm
regulation of nervous system developmentGO:0051960900.031
cilium organizationGO:0044782710.031
cell morphogenesis involved in neuron differentiationGO:00486671630.031
Zebrafish
kidney developmentGO:0001822920.030
cytoskeleton organizationGO:0007010960.030
positive regulation of embryonic developmentGO:004001930.030
positive regulation of cellular component biogenesisGO:004408930.030
cell morphogenesisGO:00009022890.030
Zebrafish
determination of bilateral symmetryGO:00098552040.030
protein metabolic processGO:00195381830.030
immune system processGO:00023762410.030
endocardium morphogenesisGO:000316040.029
anterior lateral line system developmentGO:004889890.029
positive regulation of epithelial cell proliferationGO:005067910.029
determination of intestine left right asymmetryGO:007190820.029
ear developmentGO:00435831270.029
response to external stimulusGO:00096052640.029
Zebrafish
organic substance transportGO:0071702580.029
heart loopingGO:0001947940.029
embryonic viscerocranium morphogenesisGO:0048703520.029
cell morphogenesis involved in differentiationGO:00009041950.028
Zebrafish
phagocytosis engulfmentGO:000691110.028
appendage morphogenesisGO:0035107560.028
neurological system processGO:0050877620.028
regulation of mechanoreceptor differentiationGO:004563110.028
transportGO:00068102200.028
Worm
gland developmentGO:00487321430.027
Zebrafish
neuroblast proliferationGO:000740520.027
regulation of nucleoside metabolic processGO:000911820.027
alcohol biosynthetic processGO:004616520.027
cilium morphogenesisGO:0060271850.026
cell surface receptor signaling pathwayGO:00071663250.026
striated muscle tissue developmentGO:00147061100.026
regulation of synapse organizationGO:005080730.026
embryonic heart tube formationGO:000314410.026
auditory receptor cell fate commitmentGO:000991240.026
response to abiotic stimulusGO:00096281220.026
pronephros developmentGO:0048793690.026
macromolecular complex assemblyGO:0065003350.026
convergent extensionGO:00600261180.026
response to oxygen containing compoundGO:1901700550.025
regulation of programmed cell deathGO:00430671010.025
epithelial tube morphogenesisGO:00605621480.025
endoderm developmentGO:0007492490.025
rna biosynthetic processGO:00327741810.025
Worm
cellular macromolecule biosynthetic processGO:00346452240.025
Worm
ear morphogenesisGO:0042471640.024
positive regulation of cellular metabolic processGO:0031325940.024
Worm
carboxylic acid catabolic processGO:004639530.024
gtp catabolic processGO:000618420.024
nephron epithelium morphogenesisGO:007208810.024
mesenchymal cell proliferationGO:001046310.024
aorta developmentGO:003590440.024
regulation of inner ear receptor cell differentiationGO:200098010.024
behaviorGO:0007610740.023
neural rod formationGO:001402310.023
myotome developmentGO:006105510.023
glomerulus developmentGO:0032835270.023
regulation of transcription from rna polymerase ii promoterGO:00063571140.023
Worm
regulation of signalingGO:00230512350.023
erythrocyte developmentGO:0048821240.023
regulation of multicellular organism growthGO:004001440.023
cranial nerve developmentGO:0021545420.023
regulation of synaptic plasticityGO:004816710.023
cellular protein metabolic processGO:00442671290.023
cellular response to stressGO:0033554620.023
heart contractionGO:0060047710.023
definitive hemopoiesisGO:0060216180.023
heart processGO:0003015710.022
regulation of purine nucleotide catabolic processGO:003312120.022
cardiac chamber morphogenesisGO:0003206120.022
regulation of synapse assemblyGO:005196330.022
macrophage differentiationGO:003022570.022
negative regulation of stem cell differentiationGO:200073720.021
regulation of neural precursor cell proliferationGO:200017730.021
regulation of nucleotide catabolic processGO:003081120.021
single organism localizationGO:19025782250.021
regulation of synaptic growth at neuromuscular junctionGO:000858210.020
inner ear morphogenesisGO:0042472630.020
central nervous system neuron differentiationGO:0021953740.020
Zebrafish
primitive hemopoiesisGO:0060215270.020
neuron projection morphogenesisGO:00488121610.020
Zebrafish
negative regulation of cell deathGO:0060548600.020
regulation of establishment of protein localizationGO:007020140.020
regulation of stem cell differentiationGO:200073640.019
phosphate containing compound metabolic processGO:00067961080.019
regulation of endothelial cell differentiationGO:004560130.019
mitotic cell cycleGO:0000278640.019
anterior posterior pattern specificationGO:00099521520.019
smooth muscle contractionGO:000693920.019
macromolecular complex subunit organizationGO:0043933740.019
regulation of cellular component organizationGO:0051128860.019
exocrine pancreas developmentGO:0031017280.019
response to chemicalGO:00422213200.018
Zebrafish
regionalizationGO:00030022740.018
intracellular signal transductionGO:0035556850.018
protein localization to nucleusGO:003450430.018
odontogenesis of dentin containing toothGO:004247510.018
urogenital system developmentGO:0001655970.018
gtp metabolic processGO:004603940.018
epithelial cell differentiationGO:00308551160.018
thymus developmentGO:0048538100.018
gamete generationGO:0007276330.018
peptide metabolic processGO:000651810.018
peripheral nervous system developmentGO:0007422550.018
Zebrafish
nuclear transportGO:005116940.018
erythrocyte homeostasisGO:0034101550.018
multi organism processGO:00517041340.017
embryonic eye morphogenesisGO:0048048300.017
vesicle mediated transportGO:0016192220.017
Worm
growthGO:00400071740.017
positive regulation of lymphangiogenesisGO:190149230.017
organelle assemblyGO:00709251100.017
regulation of primary metabolic processGO:00800903110.017
Worm
skeletal muscle organ developmentGO:0060538780.017
dorsal ventral pattern formationGO:00099531250.017
negative regulation of macromolecule biosynthetic processGO:0010558480.017
negative regulation of response to stimulusGO:00485851040.017
membrane fusionGO:006102520.017
artery developmentGO:0060840220.017
negative regulation of apoptotic processGO:0043066550.017
single organism membrane fusionGO:004480120.017
negative regulation of nitrogen compound metabolic processGO:0051172590.016
embryonic heart tube morphogenesisGO:00031431080.016
endoplasmic reticulum unfolded protein responseGO:003096820.016
cardiac conduction system developmentGO:000316110.016
negative regulation of cellular metabolic processGO:0031324770.016
auditory receptor cell fate determinationGO:004266820.016
guanosine containing compound catabolic processGO:190106920.016
photoreceptor cell differentiationGO:0046530550.016
cardiac cell fate commitmentGO:006091110.016
anterior lateral line nerve developmentGO:004890940.016
posterior lateral line developmentGO:0048916380.016
cell motilityGO:00488702440.015
Zebrafish
neurotransmitter secretionGO:000726920.015
negative regulation of endodermal cell fate specificationGO:004266480.015
heart joggingGO:0003146400.015
cell cycleGO:0007049930.015
spindle assemblyGO:005122520.015
endocardium formationGO:006021410.015
positive regulation of rna biosynthetic processGO:1902680570.015
Worm
epithelial cilium movement involved in determination of left right asymmetryGO:006028780.015
muscle cell developmentGO:00550011150.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
epidermal cell differentiationGO:0009913360.015
rhombomere 4 developmentGO:002157050.015
negative regulation of biosynthetic processGO:0009890550.015
organic hydroxy compound biosynthetic processGO:190161760.015
skeletal muscle tissue developmentGO:0007519670.015
positive regulation of endothelial cell differentiationGO:004560320.015
negative regulation of reproductive processGO:200024230.015
circulatory system processGO:0003013870.015
polarized epithelial cell differentiationGO:003085940.015
regulation of cell communicationGO:00106462320.015
cellular pigmentationGO:0033059300.015
organonitrogen compound metabolic processGO:1901564740.015
cell deathGO:00082191210.014
mesodermal cell fate specificationGO:0007501120.014
negative regulation of cell communicationGO:0010648960.014
regulation of organ growthGO:004662030.014
positive regulation of endothelial cell proliferationGO:000193810.014
negative regulation of nervous system developmentGO:0051961220.014
single organism reproductive processGO:0044702400.014
fin morphogenesisGO:0033334530.014
neuromast hair cell differentiationGO:0048886120.014
regulation of mesenchymal cell proliferationGO:001046410.014
inner ear developmentGO:00488391260.014
hormone secretionGO:004687920.014
antimicrobial humoral responseGO:001973020.014
macromolecule localizationGO:0033036540.014
hepaticobiliary system developmentGO:0061008980.014
startle responseGO:000196440.014
skin developmentGO:0043588540.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
somite developmentGO:0061053960.014
regulation of rho protein signal transductionGO:003502320.014
response to xenobiotic stimulusGO:0009410450.014
determination of ventral identityGO:0048264210.014
regulation of cell deathGO:00109411030.013
glial cell differentiationGO:0010001420.013
Zebrafish
liver developmentGO:0001889960.013
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.013
phagocytosisGO:000690930.013
regulation of bindingGO:005109830.013
endodermal cell fate commitmentGO:0001711180.013
regulation of nucleic acid templated transcriptionGO:19035062130.013
Worm
meiotic nuclear divisionGO:000712640.013
guanosine containing compound metabolic processGO:190106840.013
mechanoreceptor differentiationGO:0042490370.013
cellular amino acid metabolic processGO:000652070.013
olfactory placode developmentGO:0071698120.013
brain morphogenesisGO:0048854180.013
gastrulation with mouth forming secondGO:0001702440.013
neurotransmitter transportGO:000683620.013
regulation of protein catabolic processGO:004217610.013
positive regulation of nucleotide catabolic processGO:003081310.013
cilium movementGO:0003341260.013
cell cell signalingGO:0007267520.013
negative regulation of gene expressionGO:0010629650.012
regulation of reproductive processGO:200024140.012
post embryonic morphogenesisGO:000988640.012
positive regulation of developmental processGO:0051094500.012
positive regulation of signalingGO:0023056560.012
small gtpase mediated signal transductionGO:000726480.012
germ line stem cell maintenanceGO:003071820.012
septum transversum developmentGO:000334340.012
cellular response to chemical stimulusGO:00708871570.012
negative regulation of wnt signaling pathway involved in heart developmentGO:000330820.012
positive regulation of notch signaling pathwayGO:004574730.012
positive regulation of cell cycleGO:004578730.012
single organism transportGO:00447652060.012
microtubule cytoskeleton organizationGO:0000226330.012
meiotic cell cycle processGO:190304630.012
carboxylic acid metabolic processGO:0019752220.012
taxisGO:00423301090.012
Zebrafish
mesodermal cell differentiationGO:0048333210.012
negative regulation of chromosome organizationGO:200125110.012
single fertilizationGO:000733830.012
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.012
negative regulation of transcription dna templatedGO:0045892450.012
response to woundingGO:00096111160.011
apoptotic processGO:00069151160.011
fertilizationGO:000956630.011
mitotic dna integrity checkpointGO:004477440.011
aorta morphogenesisGO:003590930.011
cell cycle processGO:0022402530.011
positive regulation of gtpase activityGO:004354710.011
endothelium developmentGO:0003158250.011
deathGO:00162651210.011
negative regulation of multicellular organismal processGO:0051241690.011
inner ear receptor cell differentiationGO:0060113290.011
embryonic digestive tract morphogenesisGO:004855730.011
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
Worm
actomyosin structure organizationGO:0031032530.011
nephron morphogenesisGO:007202820.011
negative regulation of protein phosphorylationGO:000193340.011
somatic muscle developmentGO:000752540.011
embryonic limb morphogenesisGO:003032620.011
positive regulation of neurogenesisGO:0050769240.011
lipid biosynthetic processGO:0008610220.011
tissue remodelingGO:004877140.011
proepicardium developmentGO:000334240.011
branching morphogenesis of an epithelial tubeGO:0048754150.011
zymogen activationGO:003163830.011
axonal fasciculationGO:0007413110.010
cardiac ventricle formationGO:000321110.010
pigmentationGO:0043473850.010
ectodermal placode developmentGO:0071696370.010
reflexGO:006000420.010
regulation of endodermal cell fate specificationGO:0042663150.010
regulation of cellular amine metabolic processGO:003323800.010
thyroid gland developmentGO:0030878120.010
Zebrafish
notch signaling pathwayGO:0007219350.010
membrane invaginationGO:001032410.010
apoptotic process involved in morphogenesisGO:006056120.010
golgi organizationGO:000703010.010

nkx2.7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.060
dysostosisDOID:193400.014
bone diseaseDOID:008000100.014
musculoskeletal system diseaseDOID:1700.014
bone development diseaseDOID:008000600.014
connective tissue diseaseDOID:6500.014