Danio rerio

11 known processes

gfi1.2

growth factor independent 1.2

(Aliases: gfi1b,gfi1)

gfi1.2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory organ developmentGO:00074233930.651
vestibular reflexGO:006000520.442
camera type eye developmentGO:00430102220.436
reflexGO:006000420.422
inner ear developmentGO:00488391260.325
sensory organ morphogenesisGO:00905962000.263
cell projection organizationGO:00300302840.248
Human
eye developmentGO:00016542770.243
camera type eye morphogenesisGO:00485931080.201
inner ear receptor stereocilium organizationGO:006012280.182
generation of neuronsGO:00486993850.174
Human
establishment of localizationGO:00512342440.172
transmembrane transportGO:00550851200.170
eye photoreceptor cell developmentGO:0042462300.170
startle responseGO:000196440.161
central nervous system developmentGO:00074173870.156
organic substance biosynthetic processGO:19015762890.155
Human
response to external stimulusGO:00096052640.148
Human
neuron differentiationGO:00301823530.135
Human
response to abiotic stimulusGO:00096281220.130
response to stressGO:00069502630.129
regulation of multicellular organismal processGO:00512392770.128
Human
ear developmentGO:00435831270.127
gene expressionGO:00104672520.124
Human
aromatic compound biosynthetic processGO:00194382170.119
Human
negative regulation of biological processGO:00485193040.117
Human
eye photoreceptor cell differentiationGO:0001754450.116
larval developmentGO:000216420.111
single organism localizationGO:19025782250.109
cellular macromolecule biosynthetic processGO:00346452240.108
Human
single organism metabolic processGO:00447102170.097
Human
eye morphogenesisGO:00485921440.096
regulation of response to stimulusGO:00485832690.093
Human
positive regulation of biological processGO:00485182530.088
Human
ion transportGO:00068111140.087
inner ear receptor cell differentiationGO:0060113290.085
amino acid transportGO:000686520.084
neuron developmentGO:00486662620.083
Human
multicellular organism growthGO:003526440.082
cilium morphogenesisGO:0060271850.082
post embryonic organ developmentGO:004856940.077
neural retina developmentGO:0003407490.077
camera type eye photoreceptor cell differentiationGO:0060219190.075
neuromuscular process controlling balanceGO:005088530.074
regulation of macromolecule metabolic processGO:00602553170.073
Human
head developmentGO:00603223030.070
exocytosisGO:000688710.069
brain developmentGO:00074202930.069
inner ear receptor cell developmentGO:0060119200.069
regulation of cellular macromolecule biosynthetic processGO:20001122220.066
Human
photoreceptor cell developmentGO:0042461400.066
regulation of cell differentiationGO:00455951420.066
Human
cell surface receptor signaling pathwayGO:00071663250.065
Human
detection of stimulusGO:0051606290.064
retina development in camera type eyeGO:00600411460.064
maintenance of locationGO:005123540.064
biosynthetic processGO:00090582940.064
Human
regulation of reproductive processGO:200024140.064
dicarboxylic acid transportGO:000683510.063
behaviorGO:0007610740.061
cell morphogenesis involved in differentiationGO:00009041950.061
cellular biosynthetic processGO:00442492860.059
Human
equilibrioceptionGO:005095720.058
nucleic acid templated transcriptionGO:00976591810.057
Human
nitrogen compound metabolic processGO:00068073190.056
Human
regulation of primary metabolic processGO:00800903110.056
Human
visual perceptionGO:0007601170.056
epidermal cell differentiationGO:0009913360.055
negative regulation of reproductive processGO:200024230.054
negative regulation of cellular processGO:00485232830.054
Human
multi organism processGO:00517041340.053
Human
skin developmentGO:0043588540.050
rna biosynthetic processGO:00327741810.050
Human
morphogenesis of an epitheliumGO:00020093330.050
regulation of gene expressionGO:00104682650.050
Human
cellular nitrogen compound metabolic processGO:00346412900.049
Human
regulation of nucleobase containing compound metabolic processGO:00192192500.049
Human
regulation of nitrogen compound metabolic processGO:00511712510.047
Human
cilium organizationGO:0044782710.046
neurological system processGO:0050877620.045
cell morphogenesis involved in neuron differentiationGO:00486671630.045
negative regulation of multicellular organismal processGO:0051241690.045
Human
neurotransmitter transportGO:000683620.045
detection of visible lightGO:0009584120.044
transportGO:00068102200.044
epidermis developmentGO:0008544480.043
regulation of cellular biosynthetic processGO:00313262450.041
Human
regulation of metabolic processGO:00192223590.041
Human
single organism organelle organizationGO:19025891990.040
regulation of neurogenesisGO:0050767870.040
Human
regulation of macromolecule biosynthetic processGO:00105562250.040
Human
positive regulation of nucleobase containing compound metabolic processGO:0045935690.040
neuron neuron synaptic transmissionGO:000727010.039
mechanoreceptor differentiationGO:0042490370.038
heart developmentGO:00075073130.038
signal transductionGO:00071654550.037
Human
organelle assemblyGO:00709251100.036
gland developmentGO:00487321430.036
specification of symmetryGO:00097992040.035
cellular response to external stimulusGO:007149620.035
regulation of rna biosynthetic processGO:20011412130.034
Human
detection of mechanical stimulus involved in sensory perceptionGO:0050974110.034
lipid metabolic processGO:0006629520.034
Human
response to light stimulusGO:0009416460.033
cellular component morphogenesisGO:00329893360.033
embryonic organ developmentGO:00485683810.033
Zebrafish
lipid storageGO:001991510.033
cell morphogenesisGO:00009022890.033
cellular aromatic compound metabolic processGO:00067252950.032
Human
cellular response to starvationGO:000926710.032
cellular macromolecule metabolic processGO:00442603910.032
Human
heterocycle metabolic processGO:00464832900.032
Human
regulation of multicellular organism growthGO:004001440.032
photoreceptor cell differentiationGO:0046530550.032
homeostatic processGO:00425921420.032
Zebrafish
positive regulation of transportGO:005105020.032
negative regulation of behaviorGO:004852160.032
cognitionGO:005089010.032
cellular response to extracellular stimulusGO:003166820.031
cellular component assemblyGO:00226071700.031
negative regulation of response to stimulusGO:00485851040.031
response to radiationGO:0009314510.031
nucleobase containing compound biosynthetic processGO:00346542050.030
Human
system processGO:00030081850.030
regulation of epithelial cell proliferationGO:005067830.030
retinal cone cell differentiationGO:0042670120.029
nonmotile primary cilium assemblyGO:003505820.029
developmental programmed cell deathGO:001062340.029
sensory perceptionGO:0007600390.029
heart morphogenesisGO:00030071560.029
regulation of transcription from rna polymerase ii promoterGO:00063571140.029
Human
regulation of signalingGO:00230512350.028
Human
cation transportGO:0006812810.028
agingGO:000756820.028
cellular component biogenesisGO:00440851780.028
inner ear morphogenesisGO:0042472630.027
cell part morphogenesisGO:00329902460.027
leukocyte proliferationGO:007066110.027
regulation of biological qualityGO:00650082630.027
Zebrafish
positive regulation of metabolic processGO:00098931080.027
response to carbohydrateGO:000974330.027
detection of mechanical stimulusGO:0050982110.027
regulation of apoptotic processGO:0042981980.027
ion transmembrane transportGO:0034220910.026
cellular component disassemblyGO:002241110.026
odontogenesis of dentin containing toothGO:004247510.026
anion transportGO:0006820380.026
regulation of organelle assemblyGO:190211540.026
immune system processGO:00023762410.026
Human Zebrafish
regulation of cellular component organizationGO:0051128860.026
Human
detection of abiotic stimulusGO:0009582240.026
retinal rod cell developmentGO:004654840.026
regulation of developmental processGO:00507932470.026
Human
mitochondrion organizationGO:000700540.025
auditory receptor cell morphogenesisGO:000209340.025
positive regulation of cellular catabolic processGO:003133130.025
positive regulation of secretionGO:005104710.025
deathGO:00162651210.025
regulation of cell communicationGO:00106462320.025
Human
auditory receptor cell developmentGO:006011780.025
regulation of multicellular organismal developmentGO:20000262230.024
Human
nucleobase containing compound metabolic processGO:00061392740.024
Human
organic cyclic compound metabolic processGO:19013603010.024
Human
forebrain developmentGO:0030900960.024
l amino acid transportGO:001580710.024
kidney developmentGO:0001822920.024
cellular nitrogen compound biosynthetic processGO:00442712180.024
Human
synaptic vesicle recyclingGO:003646510.024
embryonic organ morphogenesisGO:00485622740.024
single organism transportGO:00447652060.024
growthGO:00400071740.024
cellular response to lipopolysaccharideGO:007122230.023
Human
regulation of establishment of protein localizationGO:007020140.023
negative regulation of nitrogen compound metabolic processGO:0051172590.023
Human
regulation of cytokine productionGO:000181730.023
cellular response to organic substanceGO:00713101050.023
Human
response to chemicalGO:00422213200.023
Human
gtp metabolic processGO:004603940.023
neuromuscular processGO:005090570.023
response to hexoseGO:000974630.023
positive regulation of secretion by cellGO:190353210.022
hepaticobiliary system developmentGO:0061008980.022
sensory perception of mechanical stimulusGO:0050954160.022
regulation of programmed cell deathGO:00430671010.022
neuron projection developmentGO:00311751800.022
Human
positive regulation of catabolic processGO:000989640.022
organic cyclic compound biosynthetic processGO:19013622230.022
Human
positive regulation of map kinase activityGO:004340630.021
blood vessel endothelial cell migrationGO:0043534180.021
cellular response to chemical stimulusGO:00708871570.021
Human
female gonad developmentGO:000858540.021
small molecule metabolic processGO:0044281770.021
Human
response to monosaccharideGO:003428430.021
regulation of anatomical structure morphogenesisGO:00226031300.021
regulation of cell activationGO:005086510.021
regulation of cell deathGO:00109411030.021
regulation of retina development in camera type eyeGO:190286620.021
carboxylic acid transportGO:004694280.021
epithelial cilium movementGO:0003351150.021
positive regulation of gene expressionGO:0010628710.021
compound eye developmentGO:004874920.020
ovulation cycleGO:004269820.020
regulation of rna metabolic processGO:00512522240.020
Human
otic vesicle developmentGO:0071599420.020
cell deathGO:00082191210.020
regulation of muscle contractionGO:000693730.020
cellular response to nutrient levelsGO:003166920.020
cell cycle g2 m phase transitionGO:004483940.020
regulation of ion transmembrane transporter activityGO:003241220.020
regulation of organ growthGO:004662030.020
cellular response to molecule of bacterial originGO:007121930.020
Human
stem cell maintenanceGO:001982740.020
urogenital system developmentGO:0001655970.020
cellular response to light stimulusGO:007148240.020
sensory perception of light stimulusGO:0050953190.020
somatic muscle developmentGO:000752540.020
regulation of protein catabolic processGO:004217610.019
organonitrogen compound metabolic processGO:1901564740.019
spermatid developmentGO:000728620.019
b cell differentiationGO:003018310.019
amine metabolic processGO:000930820.019
regulation of neuron differentiationGO:0045664560.019
Human
lateral line system developmentGO:0048925760.019
activation of mapk activityGO:000018730.019
chordate embryonic developmentGO:00430092710.019
negative regulation of macromolecule biosynthetic processGO:0010558480.018
Human
organic substance transportGO:0071702580.018
diencephalon developmentGO:0021536580.018
programmed cell deathGO:00125011190.018
macromolecule biosynthetic processGO:00090592270.018
Human
regulation of glial cell differentiationGO:004568540.018
regulation of protein transportGO:005122330.018
renal system developmentGO:0072001940.018
liver developmentGO:0001889960.018
regulation of synapse organizationGO:005080730.018
membrane fusionGO:006102520.018
cell projection assemblyGO:0030031640.018
positive regulation of translationGO:004572710.018
regulation of synapse assemblyGO:005196330.018
transcription from rna polymerase ii promoterGO:0006366800.018
Human
cellular localizationGO:0051641970.018
positive regulation of cellular processGO:00485222010.017
Human
heterocycle biosynthetic processGO:00181302150.017
Human
b cell activationGO:004211320.017
oxoacid metabolic processGO:0043436310.017
regulation of transmembrane transporter activityGO:002289820.017
organelle organizationGO:00069962270.017
cell chemotaxisGO:0060326170.017
epithelial cell morphogenesisGO:000338220.017
guanosine containing compound metabolic processGO:190106840.017
response to glucoseGO:000974930.017
regulation of transcription dna templatedGO:00063552130.017
Human
sequestering of calcium ionGO:005120830.017
retina morphogenesis in camera type eyeGO:0060042790.017
positive regulation of cellular component biogenesisGO:004408930.017
cation homeostasisGO:0055080330.016
gastrulationGO:00073692080.016
response to oxygen containing compoundGO:1901700550.016
Human
extrinsic apoptotic signaling pathwayGO:009719130.016
lateral line developmentGO:0048882660.016
hematopoietic or lymphoid organ developmentGO:00485341910.016
Zebrafish
macroautophagyGO:001623610.016
establishment of localization in cellGO:0051649770.016
homeostasis of number of cells within a tissueGO:004887340.016
regulation of cellular metabolic processGO:00313233200.016
Human
positive regulation of biosynthetic processGO:0009891680.016
development of primary female sexual characteristicsGO:004654540.016
phagocytosisGO:000690930.016
axon developmentGO:00615641660.016
ear morphogenesisGO:0042471640.016
detection of mechanical stimulus involved in sensory perception of soundGO:005091030.016
single organism intracellular transportGO:1902582250.016
cellular amine metabolic processGO:004410620.016
regulation of purine nucleotide catabolic processGO:003312120.016
regionalizationGO:00030022740.016
gtp catabolic processGO:000618420.016
lymphocyte proliferationGO:004665110.015
carbohydrate homeostasisGO:003350010.015
negative regulation of macromolecule metabolic processGO:0010605760.015
Human
protein polymerizationGO:005125840.015
positive regulation of macromolecule metabolic processGO:0010604930.015
regulation of extrinsic apoptotic signaling pathwayGO:200123630.015
synaptic vesicle localizationGO:009747910.015
lamellipodium assemblyGO:003003210.015
single organism behaviorGO:0044708240.015
regulation of cell morphogenesisGO:0022604420.015
protein complex subunit organizationGO:0071822460.015
negative regulation of nucleobase containing compound metabolic processGO:0045934590.015
Human
mononuclear cell proliferationGO:003294310.015
macromolecular complex disassemblyGO:003298410.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
Human
olfactory lobe developmentGO:002198840.015
homeostasis of number of cellsGO:0048872620.015
Zebrafish
guanosine containing compound catabolic processGO:190106920.015
stem cell proliferationGO:007208940.015
antimicrobial humoral responseGO:001973020.015
regulation of protein metabolic processGO:0051246560.015
regulation of dendrite morphogenesisGO:004881430.014
positive regulation of signal transductionGO:0009967560.014
Human
multi organism cellular processGO:004476420.014
regulation of tube sizeGO:003515020.014
protein homooligomerizationGO:005126030.014
negative regulation of cell deathGO:0060548600.014
hematopoietic progenitor cell differentiationGO:0002244230.014
regulation of neural retina developmentGO:006107420.014
small molecule catabolic processGO:004428230.014
positive regulation of epithelial cell proliferationGO:005067910.014
positive regulation of stress activated mapk cascadeGO:003287430.014
negative regulation of programmed cell deathGO:0043069580.014
protein localizationGO:0008104400.014
apoptotic processGO:00069151160.014
regulation of nervous system developmentGO:0051960900.014
Human
negative regulation of signalingGO:0023057960.014
regulation of response to stressGO:0080134360.014
Human
regulation of behaviorGO:0050795240.014
positive regulation of cellular metabolic processGO:0031325940.014
ovulation cycle processGO:002260220.014
regulation of cytoplasmic transportGO:190364940.014
apoptotic process involved in developmentGO:190274220.014
nuclear exportGO:005116810.013
glucose homeostasisGO:004259310.013
regulation of transporter activityGO:003240920.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.013
determination of left right symmetryGO:00073681790.013
regulation of cell shapeGO:000836010.013
post embryonic organ morphogenesisGO:004856310.013
positive regulation of cytokine productionGO:000181920.013
regulation of jak stat cascadeGO:004642530.013
cellular response to biotic stimulusGO:007121630.013
Human
anion transmembrane transportGO:0098656120.013
meiotic nuclear divisionGO:000712640.013
detection of external stimulusGO:0009581240.013
regulation of biosynthetic processGO:00098892500.013
Human
negative regulation of apoptotic processGO:0043066550.013
negative regulation of metabolic processGO:0009892860.013
Human
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.013
neuroblast proliferationGO:000740520.013
protein metabolic processGO:00195381830.013
proteasomal protein catabolic processGO:001049820.013
ion homeostasisGO:0050801410.013
synaptic vesicle transportGO:004848910.013
neuron projection morphogenesisGO:00488121610.013
cellular response to lipidGO:0071396390.013
Human
response to drugGO:004249330.012
synaptic growth at neuromuscular junctionGO:005112420.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
positive regulation of nucleic acid templated transcriptionGO:1903508570.012
synaptic target recognitionGO:000803910.012
regulation of circadian rhythmGO:004275240.012
epithelial cell differentiationGO:00308551160.012
nucleic acid metabolic processGO:00903042440.012
Human
cilium movementGO:0003341260.012
autophagyGO:000691440.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
nephron epithelium morphogenesisGO:007208810.012
photoreceptor cell fate commitmentGO:004655210.012
phosphorus metabolic processGO:00067931090.012
innate immune responseGO:0045087130.012
regulation of protein bindingGO:004339330.012
positive regulation of protein complex assemblyGO:003133420.012
negative regulation of multi organism processGO:004390130.012
lymphangiogenesisGO:0001946250.012
positive regulation of cellular biosynthetic processGO:0031328680.012
neural crest cell differentiationGO:0014033720.012
central nervous system neuron differentiationGO:0021953740.012
regulation of nucleoside metabolic processGO:000911820.012
response to uvGO:000941130.012
cellular ketone metabolic processGO:0042180110.012
regulation of wnt signaling pathwayGO:0030111530.012
detection of stimulus involved in sensory perceptionGO:0050906210.012
positive regulation of multicellular organismal processGO:0051240520.011
regulation of protein complex assemblyGO:004325430.011
regulation of cell developmentGO:00602841000.011
Human
ovarian follicle developmentGO:000154120.011
toll like receptor signaling pathwayGO:000222440.011
Human
cation transmembrane transportGO:0098655650.011
protein dephosphorylationGO:000647030.011
protein complex disassemblyGO:004324110.011
negative regulation of cell differentiationGO:0045596460.011
Human
proepicardium developmentGO:000334240.011
nuclear transportGO:005116940.011
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.011
response to salt stressGO:0009651100.011
cardiac atrium developmentGO:000323040.011
glucose importGO:004632320.011
hair cell differentiationGO:0035315320.011
protein importGO:001703830.011
ribosomal small subunit biogenesisGO:004227420.011
regulation of bindingGO:005109830.011
glial cell proliferationGO:001400940.011
negative regulation of signal transductionGO:0009968940.011
rna metabolic processGO:00160702190.011
Human
cellular protein catabolic processGO:004425740.011
regulation of gtpase activityGO:004308720.011
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.011
Human
positive regulation of jak stat cascadeGO:004642720.011
phosphate containing compound metabolic processGO:00067961080.011
regulation of stem cell differentiationGO:200073640.011
negative regulation of rna biosynthetic processGO:1902679450.011
Human
intracellular signal transductionGO:0035556850.011
protein secretionGO:000930610.011
regulation of calcium ion transportGO:005192420.011
striated muscle cell differentiationGO:00511461290.011
ectodermal placode developmentGO:0071696370.011
lymph vessel developmentGO:0001945270.011
response to alkaloidGO:004327920.011
positive regulation of nucleoside metabolic processGO:004597910.011
cellular protein metabolic processGO:00442671290.011
regulation of nucleocytoplasmic transportGO:004682220.011
regulation of membrane potentialGO:0042391230.011
innervationGO:006038430.010
stem cell differentiationGO:00488631170.010
tube morphogenesisGO:00352393490.010
neurotransmitter secretionGO:000726920.010
cell projection morphogenesisGO:00488582440.010
female sex differentiationGO:004666040.010
blood circulationGO:0008015870.010
endocrine system developmentGO:0035270650.010
nerve developmentGO:0021675450.010
actin filament organizationGO:0007015150.010
positive regulation of cellular amine metabolic processGO:003324000.010
regulation of cellular amine metabolic processGO:003323800.010
regulation of cellular protein catabolic processGO:190336210.010
cellular response to retinoic acidGO:007130010.010
somatic stem cell maintenanceGO:003501910.010
nucleocytoplasmic transportGO:000691340.010
single organism nuclear importGO:190259330.010
sexual reproductionGO:0019953360.010
regulation of intracellular protein transportGO:003315730.010
protein targeting to membraneGO:000661210.010
anatomical structure arrangementGO:004853220.010
negative regulation of secretionGO:005104820.010
catabolic processGO:0009056320.010
cellular amide metabolic processGO:004360340.010

gfi1.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.028
disease of cellular proliferationDOID:1456600.028
disease of anatomical entityDOID:700.016
Human
nervous system diseaseDOID:86300.016
sensory system diseaseDOID:005015500.016
organ system cancerDOID:005068600.016
auditory system diseaseDOID:274200.015
nonsyndromic deafnessDOID:005056300.015