Danio rerio

0 known processes

tph1a

tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a

(Aliases: tph1,tphD1,tph)

tph1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
signal transductionGO:00071654550.336
Worm
response to chemicalGO:00422213200.257
Zebrafish Worm
transportGO:00068102200.213
nitrogen compound metabolic processGO:00068073190.158
Zebrafish Worm Fly
regulation of primary metabolic processGO:00800903110.154
regionalizationGO:00030022740.146
embryo development ending in birth or egg hatchingGO:00097922710.144
Worm
single organism metabolic processGO:00447102170.129
Zebrafish Mouse Worm Fly
heart developmentGO:00075073130.129
response to external stimulusGO:00096052640.123
response to abiotic stimulusGO:00096281220.120
convergent extensionGO:00600261180.117
negative regulation of signalingGO:0023057960.116
intracellular signal transductionGO:0035556850.113
developmental growthGO:00485891660.109
biosynthetic processGO:00090582940.100
Zebrafish Worm Fly
neuron projection guidanceGO:0097485860.100
skeletal system developmentGO:00015011810.099
organic substance transportGO:0071702580.098
regulation of cell communicationGO:00106462320.093
Worm
cell surface receptor signaling pathwayGO:00071663250.093
Worm
single organism localizationGO:19025782250.091
negative regulation of cell communicationGO:0010648960.089
regulation of macromolecule metabolic processGO:00602553170.088
regulation of response to stimulusGO:00485832690.085
Worm Fly
regulation of establishment of protein localizationGO:007020140.084
muscle structure developmentGO:00610611960.082
regulation of signalingGO:00230512350.079
Worm
phosphate containing compound metabolic processGO:00067961080.076
negative regulation of signal transductionGO:0009968940.075
cellular localizationGO:0051641970.073
regulation of signal transductionGO:00099662250.072
Worm
cell morphogenesisGO:00009022890.071
brain developmentGO:00074202930.071
organic cyclic compound metabolic processGO:19013603010.071
Zebrafish Worm Fly
organic substance biosynthetic processGO:19015762890.071
Zebrafish Worm Fly
central nervous system developmentGO:00074173870.070
Zebrafish
organonitrogen compound metabolic processGO:1901564740.069
Zebrafish Worm Fly
establishment of localizationGO:00512342440.068
cell projection organizationGO:00300302840.067
neuron developmentGO:00486662620.067
cognitionGO:005089010.067
generation of neuronsGO:00486993850.066
Zebrafish
morphogenesis of an epitheliumGO:00020093330.065
cortical actin cytoskeleton organizationGO:003086610.063
cellular component movementGO:00069283350.062
programmed cell deathGO:00125011190.060
regulation of protein transportGO:005122330.060
cell morphogenesis involved in neuron differentiationGO:00486671630.058
system processGO:00030081850.058
cell deathGO:00082191210.057
regulation of cellular metabolic processGO:00313233200.057
chordate embryonic developmentGO:00430092710.056
gastrulation with mouth forming secondGO:0001702440.056
taxisGO:00423301090.054
positive regulation of cell communicationGO:0010647560.054
Worm
transmembrane transportGO:00550851200.053
cellular nitrogen compound biosynthetic processGO:00442712180.053
Zebrafish Worm Fly
positive regulation of cell cycleGO:004578730.053
alpha amino acid metabolic processGO:190160530.052
Worm
positive regulation of cellular metabolic processGO:0031325940.051
homeostatic processGO:00425921420.050
cell fate commitmentGO:0045165990.050
cellular macromolecule metabolic processGO:00442603910.050
hindbrain developmentGO:0030902910.049
hormone secretionGO:004687920.047
neuron differentiationGO:00301823530.047
Zebrafish
neurological system processGO:0050877620.047
behaviorGO:0007610740.045
Worm Fly
positive regulation of transportGO:005105020.045
cortical cytoskeleton organizationGO:003086510.045
cellular aromatic compound metabolic processGO:00067252950.045
Zebrafish Worm Fly
ameboidal type cell migrationGO:00016671430.045
axon developmentGO:00615641660.045
establishment of localization in cellGO:0051649770.044
deathGO:00162651210.044
immune system processGO:00023762410.043
axon guidanceGO:0007411860.043
gland developmentGO:00487321430.042
Mouse
circadian sleep wake cycle sleepGO:005080210.042
Fly
regulation of cellular biosynthetic processGO:00313262450.042
locomotionGO:00400113130.042
sensory organ developmentGO:00074233930.041
single organism biosynthetic processGO:0044711710.040
Worm
regulation of multicellular organism growthGO:004001440.040
anterior posterior pattern specificationGO:00099521520.039
negative regulation of response to stimulusGO:00485851040.039
stem cell divisionGO:001714510.039
pigmentationGO:0043473850.039
regulation of macromolecule biosynthetic processGO:00105562250.039
synaptic transmission cholinergicGO:000727140.039
transcription from rna polymerase ii promoterGO:0006366800.038
regulation of cytoplasmic transportGO:190364940.038
regulation of apoptotic processGO:0042981980.037
monoamine transportGO:001584410.037
cell projection morphogenesisGO:00488582440.037
organophosphate metabolic processGO:0019637370.036
embryonic organ morphogenesisGO:00485622740.036
cellular response to external stimulusGO:007149620.036
nucleic acid templated transcriptionGO:00976591810.036
response to ketoneGO:190165410.036
dorsal ventral pattern formationGO:00099531250.036
neuron projection developmentGO:00311751800.035
regulation of embryonic developmentGO:0045995470.035
regulation of gtpase activityGO:004308720.035
positive regulation of cellular processGO:00485222010.035
Mouse Worm
regulation of cell differentiationGO:00455951420.035
Mouse
guanosine containing compound catabolic processGO:190106920.034
regulation of cell deathGO:00109411030.034
wnt signaling pathwayGO:0016055800.034
single organism cellular localizationGO:1902580460.034
regulation of metabolic processGO:00192223590.034
fin regenerationGO:0031101510.034
peptide transportGO:001583310.033
cell migrationGO:00164772370.033
cell part morphogenesisGO:00329902460.033
cellular component morphogenesisGO:00329893360.033
single organism transportGO:00447652060.033
regulation of circadian rhythmGO:004275240.032
Fly
regulation of circadian sleep wake cycleGO:004274910.032
Fly
growthGO:00400071740.032
mitochondrion organizationGO:000700540.032
skeletal system morphogenesisGO:00487051020.032
oxoacid metabolic processGO:0043436310.032
Worm
protein metabolic processGO:00195381830.031
regulation of anatomical structure morphogenesisGO:00226031300.031
regulation of reproductive processGO:200024140.031
Worm
cellular response to steroid hormone stimulusGO:0071383310.031
Zebrafish
organelle organizationGO:00069962270.030
agingGO:000756820.030
Worm
digestive system developmentGO:00551232890.030
response to stressGO:00069502630.030
regulation of synaptic plasticityGO:004816710.030
chemotaxisGO:00069351040.030
gtp metabolic processGO:004603940.029
regulation of intracellular protein transportGO:003315730.029
axonogenesisGO:00074091520.029
small molecule metabolic processGO:0044281770.029
Worm
mitotic cell cycleGO:0000278640.029
actomyosin structure organizationGO:0031032530.029
cell morphogenesis involved in differentiationGO:00009041950.029
response to uvGO:000941130.029
organic acid metabolic processGO:0006082310.029
Worm
digestive tract developmentGO:00485652650.029
regulation of synapse organizationGO:005080730.028
g protein coupled receptor signaling pathwayGO:0007186740.028
gastrulationGO:00073692080.028
protein localization to nucleusGO:003450430.028
muscle organ developmentGO:00075171010.028
regulation of transcription from rna polymerase ii promoterGO:00063571140.028
neuroblast proliferationGO:000740520.028
cell cell signalingGO:0007267520.028
establishment of organelle localizationGO:0051656450.027
epithelial cell differentiationGO:00308551160.027
gene expressionGO:00104672520.027
positive regulation of cell deathGO:0010942290.027
nuclear transportGO:005116940.027
regulation of developmental processGO:00507932470.027
Mouse
defense responseGO:0006952470.027
aromatic compound biosynthetic processGO:00194382170.027
Zebrafish Worm Fly
neuronal action potentialGO:0019228180.027
maintenance of locationGO:005123540.027
Worm
nucleocytoplasmic transportGO:000691340.026
cellular response to hormone stimulusGO:0032870390.026
Zebrafish
larval developmentGO:000216420.026
Worm
positive regulation of metabolic processGO:00098931080.026
blood vessel morphogenesisGO:00485142160.026
stem cell proliferationGO:007208940.025
rna biosynthetic processGO:00327741810.025
regulation of membrane potentialGO:0042391230.025
positive regulation of muscle organ developmentGO:004863610.025
negative regulation of protein phosphorylationGO:000193340.025
inositol lipid mediated signalingGO:004801720.025
heterocycle biosynthetic processGO:00181302150.025
Zebrafish Worm Fly
regulation of cell developmentGO:00602841000.025
regulation of gene expressionGO:00104682650.025
proteolysis involved in cellular protein catabolic processGO:005160330.024
transmission of nerve impulseGO:0019226190.024
positive regulation of nucleobase containing compound metabolic processGO:0045935690.024
regulation of circadian sleep wake cycle sleepGO:004518710.024
Fly
cellular response to lipidGO:0071396390.024
Zebrafish
regulation of phosphorus metabolic processGO:0051174430.024
hepaticobiliary system developmentGO:0061008980.023
regulation of nucleoside metabolic processGO:000911820.023
mesenchyme developmentGO:00604851270.023
phosphorus metabolic processGO:00067931090.023
liver developmentGO:0001889960.023
macromolecule biosynthetic processGO:00090592270.023
cellular nitrogen compound metabolic processGO:00346412900.023
Zebrafish Worm Fly
nitrogen compound transportGO:0071705230.023
endoderm developmentGO:0007492490.023
morphogenesis of an epithelial sheetGO:0002011490.023
cell growthGO:0016049570.023
phagocytosisGO:000690930.022
type b pancreatic cell developmentGO:000332340.022
multicellular organismal signalingGO:0035637220.022
metal ion homeostasisGO:0055065260.022
ion transportGO:00068111140.022
cell cycleGO:0007049930.022
positive regulation of macromolecule metabolic processGO:0010604930.022
protein modification processGO:00362111000.022
fin developmentGO:0033333770.022
nucleobase containing compound metabolic processGO:00061392740.022
protein importGO:001703830.022
regulation of endodermal cell fate specificationGO:0042663150.022
eye developmentGO:00016542770.021
connective tissue developmentGO:0061448990.021
circadian regulation of gene expressionGO:003292280.021
guanosine containing compound metabolic processGO:190106840.021
developmental cell growthGO:0048588520.021
regulation of rna biosynthetic processGO:20011412130.021
apoptotic processGO:00069151160.021
regulation of cellular component organizationGO:0051128860.021
cation transmembrane transportGO:0098655650.020
columnar cuboidal epithelial cell differentiationGO:0002065380.020
synaptic growth at neuromuscular junctionGO:005112420.020
regulation of multicellular organismal processGO:00512392770.020
Worm Fly
regulation of cell activationGO:005086510.020
nuclear exportGO:005116810.020
negative regulation of biological processGO:00485193040.020
amine metabolic processGO:000930820.020
Worm
response to steroid hormoneGO:0048545350.020
Zebrafish
tube morphogenesisGO:00352393490.020
cell fate specificationGO:0001708680.020
centrosome cycleGO:000709810.020
actin polymerization or depolymerizationGO:000815420.020
response to organic substanceGO:00100331530.020
Zebrafish Worm
developmental pigmentationGO:0048066480.020
multi organism processGO:00517041340.020
Worm
determination of bilateral symmetryGO:00098552040.020
central nervous system neuron differentiationGO:0021953740.020
Zebrafish
convergent extension involved in gastrulationGO:0060027710.020
positive regulation of secretionGO:005104710.019
cellular response to organic cyclic compoundGO:0071407380.019
Zebrafish
establishment of protein localization to organelleGO:007259440.019
regulation of protein modification by small protein conjugation or removalGO:190332030.019
synaptic vesicle localizationGO:009747910.019
regulation of multicellular organismal developmentGO:20000262230.019
small gtpase mediated signal transductionGO:000726480.019
cellular macromolecule biosynthetic processGO:00346452240.019
peptidyl serine modificationGO:001820920.018
regulation of biological qualityGO:00650082630.018
Worm
cartilage developmentGO:0051216960.018
regulation of canonical wnt signaling pathwayGO:0060828340.018
appendage developmentGO:0048736800.018
positive regulation of signalingGO:0023056560.018
Worm
macromolecule modificationGO:00434121110.018
single organism membrane organizationGO:0044802200.018
regulation of bindingGO:005109830.018
negative regulation of protein kinase activityGO:000646940.018
muscle tissue developmentGO:00605371100.018
establishment of synaptic vesicle localizationGO:009748010.018
spinal cord motor neuron differentiationGO:0021522260.018
Zebrafish
positive regulation of biological processGO:00485182530.018
Mouse Worm
cation homeostasisGO:0055080330.018
sensory perception of chemical stimulusGO:000760630.018
circadian sleep wake cycle processGO:002241020.017
Fly
entrainment of circadian clockGO:000964920.017
cellular response to oxygen levelsGO:007145310.017
epiboly involved in gastrulation with mouth forming secondGO:0055113350.017
fatty acid biosynthetic processGO:000663340.017
cell motilityGO:00488702440.017
cellular response to light stimulusGO:007148240.017
regulation of extrinsic apoptotic signaling pathwayGO:200123630.017
cellular amine metabolic processGO:004410620.017
Worm
cellular response to extracellular stimulusGO:003166820.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
single organism organelle organizationGO:19025891990.017
mechanosensory behaviorGO:000763820.017
positive regulation of striated muscle tissue developmentGO:004584410.017
skeletal muscle organ developmentGO:0060538780.016
carboxylic acid metabolic processGO:0019752220.016
Worm
regulation of localizationGO:00328791040.016
regulation of blood pressureGO:000821710.016
regulation of nucleotide catabolic processGO:003081120.016
regulation of phosphate metabolic processGO:0019220430.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.016
Worm
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.016
response to radiationGO:0009314510.016
cellular protein metabolic processGO:00442671290.016
regulation of catalytic activityGO:0050790550.016
exocrine pancreas developmentGO:0031017280.016
glandular epithelial cell differentiationGO:000206790.016
negative regulation of molecular functionGO:0044092230.016
locomotor rhythmGO:004547530.016
regulation of protein bindingGO:004339330.015
energy reserve metabolic processGO:000611220.015
synaptic vesicle transportGO:004848910.015
negative regulation of macromolecule metabolic processGO:0010605760.015
nuclear importGO:005117030.015
nucleobase containing compound biosynthetic processGO:00346542050.015
cellular response to starvationGO:000926710.015
macromolecule localizationGO:0033036540.015
Worm
positive regulation of secretion by cellGO:190353210.015
microtubule based processGO:0007017600.015
regulation of protein complex assemblyGO:004325430.015
single organism intracellular transportGO:1902582250.015
negative regulation of secretionGO:005104820.015
actin cytoskeleton organizationGO:0030036630.015
proteasomal protein catabolic processGO:001049820.015
developmental growth involved in morphogenesisGO:0060560860.015
fin morphogenesisGO:0033334530.015
carbohydrate derivative metabolic processGO:1901135610.015
cellular protein catabolic processGO:004425740.015
response to growth factorGO:0070848390.015
Worm
urogenital system developmentGO:0001655970.014
regulation of cellular amine metabolic processGO:003323800.014
response to hexoseGO:000974630.014
sensory organ morphogenesisGO:00905962000.014
actin filament based processGO:0030029640.014
positive regulation of map kinase activityGO:004340630.014
cellular biosynthetic processGO:00442492860.014
Zebrafish Worm Fly
embryonic skeletal system morphogenesisGO:0048704930.014
mitotic cell cycle processGO:1903047480.014
regulation of gtp catabolic processGO:003312420.014
pancreas developmentGO:0031016840.014
hormone transportGO:000991420.014
regulation of cell cycleGO:0051726520.014
regulation of nucleocytoplasmic transportGO:004682220.014
head developmentGO:00603223030.014
cellular response to decreased oxygen levelsGO:003629410.014
negative regulation of cellular processGO:00485232830.014
positive regulation of rna biosynthetic processGO:1902680570.014
peptidyl serine phosphorylationGO:001810510.014
meiotic nuclear divisionGO:000712640.014
protein targeting to nucleusGO:004474430.014
localization of cellGO:00516742440.014
regulation of transportGO:0051049450.014
protein localizationGO:0008104400.014
retina morphogenesis in camera type eyeGO:0060042790.014
negative regulation of cell deathGO:0060548600.014
regulation of programmed cell deathGO:00430671010.014
action potentialGO:0001508190.013
regulation of cell shapeGO:000836010.013
cellular response to nutrient levelsGO:003166920.013
organelle localizationGO:0051640490.013
positive regulation of cellular catabolic processGO:003133130.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
regulation of synapse assemblyGO:005196330.013
striated muscle cell differentiationGO:00511461290.013
angiogenesisGO:00015251580.013
endodermal cell fate specificationGO:0001714170.013
regulation of gastrulationGO:0010470240.013
protein import into nucleusGO:000660630.013
regulation of purine nucleotide catabolic processGO:003312120.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
positive regulation of cell divisionGO:005178120.013
response to woundingGO:00096111160.013
cell substrate adhesionGO:003158940.013
cellular response to endogenous stimulusGO:0071495680.013
Zebrafish Worm
phototransductionGO:000760220.013
single organism behaviorGO:0044708240.013
Fly
regulation of oocyte developmentGO:006028130.013
positive regulation of response to stimulusGO:0048584800.013
Worm
morphogenesis of embryonic epitheliumGO:0016331300.013
multicellular organism growthGO:003526440.013
renal system developmentGO:0072001940.013
negative regulation of kinase activityGO:003367340.013
modification dependent macromolecule catabolic processGO:004363230.013
response to estrogenGO:0043627270.013
Zebrafish
sleepGO:003043110.013
Fly
negative regulation of protein transportGO:005122430.013
membrane fusionGO:006102520.013
regulation of carbohydrate metabolic processGO:000610940.013
regulation of nucleobase containing compound metabolic processGO:00192192500.012
response to monosaccharideGO:003428430.012
multi organism cellular processGO:004476420.012
cell cycle processGO:0022402530.012
phosphorylationGO:0016310690.012
biological adhesionGO:0022610400.012
positive regulation of transcription dna templatedGO:0045893570.012
response to temperature stimulusGO:0009266150.012
gtp catabolic processGO:000618420.012
ras protein signal transductionGO:000726570.012
meiotic cell cycle processGO:190304630.012
exocytosisGO:000688710.012
cell proliferationGO:0008283800.012
chemical homeostasisGO:0048878490.012
axon extensionGO:0048675450.012
oocyte maturationGO:000155640.012
lipid metabolic processGO:0006629520.012
camera type eye developmentGO:00430102220.012
negative regulation of catalytic activityGO:0043086210.012
cellular ketone metabolic processGO:0042180110.012
negative regulation of intracellular transportGO:003238730.012
regulation of biosynthetic processGO:00098892500.012
regulation of protein modification processGO:0031399290.012
cellular component biogenesisGO:00440851780.012
neuron projection morphogenesisGO:00488121610.012
cellular response to growth factor stimulusGO:0071363390.012
Worm
heart morphogenesisGO:00030071560.012
positive regulation of cellular component biogenesisGO:004408930.012
response to salt stressGO:0009651100.012
regulation of phGO:000688530.011
response to fungusGO:0009620250.011
forebrain developmentGO:0030900960.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.011
digestive tract morphogenesisGO:00485462310.011
embryonic organ developmentGO:00485683810.011
positive regulation of catabolic processGO:000989640.011
regulation of transcription dna templatedGO:00063552130.011
regulation of protein metabolic processGO:0051246560.011
cell differentiation in spinal cordGO:0021515400.011
Zebrafish
nucleotide metabolic processGO:0009117280.011
cellular response to hypoxiaGO:007145610.011
skin developmentGO:0043588540.011
negative regulation of intracellular signal transductionGO:1902532220.011
macromolecular complex disassemblyGO:003298410.011
stem cell differentiationGO:00488631170.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
locomotory behaviorGO:0007626340.011
rna metabolic processGO:00160702190.011
neuron deathGO:0070997210.011
ion homeostasisGO:0050801410.011
cell migration involved in gastrulationGO:0042074790.011
cellular protein modification processGO:00064641000.011
embryonic skeletal system developmentGO:0048706970.011
positive regulation of biosynthetic processGO:0009891680.011
detection of external stimulusGO:0009581240.011
kidney developmentGO:0001822920.011
response to hydrogen peroxideGO:004254230.011
ear morphogenesisGO:0042471640.011
negative regulation of cysteine type endopeptidase activityGO:200011780.011
striated muscle tissue developmentGO:00147061100.010
vasculature developmentGO:00019442780.010
ion transmembrane transportGO:0034220910.010
pronephros developmentGO:0048793690.010
carbohydrate homeostasisGO:003350010.010
negative regulation of metabolic processGO:0009892860.010
protein phosphorylationGO:0006468470.010
cardiocyte differentiationGO:0035051440.010
regulation of metal ion transportGO:001095940.010
ubiquitin dependent protein catabolic processGO:000651130.010
cardiac atrium developmentGO:000323040.010
nephron morphogenesisGO:007202820.010
mononuclear cell proliferationGO:003294310.010
chemosensory behaviorGO:000763510.010
establishment of endothelial barrierGO:006102830.010
regulation of tube sizeGO:003515020.010
intrinsic apoptotic signaling pathwayGO:0097193200.010
single organism nuclear importGO:190259330.010
response to osmotic stressGO:0006970110.010

tph1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.041
nervous system diseaseDOID:86300.041
sensory system diseaseDOID:005015500.020
eye diseaseDOID:561400.020
eye and adnexa diseaseDOID:149200.020