Danio rerio

30 known processes

tpte

transmembrane phosphatase with tensin homology

(Aliases: vsp,wu:fi24b06,tpip,wu:fd20e11,MGC113432)

tpte biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.282
cortical actin cytoskeleton organizationGO:003086610.138
cortical cytoskeleton organizationGO:003086510.133
positive regulation of transportGO:005105020.130
organelle fusionGO:004828430.110
establishment of localizationGO:00512342440.102
cellular component assemblyGO:00226071700.099
negative regulation of biological processGO:00485193040.097
agingGO:000756820.092
cell projection organizationGO:00300302840.085
endosomal transportGO:001619720.078
cytoskeleton dependent cytokinesisGO:006164030.078
regulation of bindingGO:005109830.077
single organism transportGO:00447652060.072
heart developmentGO:00075073130.069
muscle structure developmentGO:00610611960.069
hormone transportGO:000991420.067
single organism membrane fusionGO:004480120.064
response to chemicalGO:00422213200.064
signal transductionGO:00071654550.063
cellular component movementGO:00069283350.062
membrane fusionGO:006102520.061
generation of neuronsGO:00486993850.057
cellular component biogenesisGO:00440851780.056
muscle tissue developmentGO:00605371100.055
regulation of synapse organizationGO:005080730.054
single organism localizationGO:19025782250.053
establishment of protein localization to plasma membraneGO:009000210.053
protein localization to plasma membraneGO:007265910.053
protein targeting to nucleusGO:004474430.051
guanosine containing compound metabolic processGO:190106840.051
cytokinesisGO:000091030.050
neuron developmentGO:00486662620.050
lipid storageGO:001991510.050
localization of cellGO:00516742440.049
maintenance of locationGO:005123540.048
regulation of synapse assemblyGO:005196330.048
protein import into nucleusGO:000660630.047
regionalizationGO:00030022740.044
protein localization to nucleusGO:003450430.044
membrane lipid biosynthetic processGO:004646720.044
adult behaviorGO:003053420.043
regulation of multicellular organism growthGO:004001440.042
cellular component assembly involved in morphogenesisGO:00109271070.042
blood vessel developmentGO:00015682460.042
regulation of biological qualityGO:00650082630.042
neuron differentiationGO:00301823530.041
post golgi vesicle mediated transportGO:000689210.041
embryo development ending in birth or egg hatchingGO:00097922710.041
single organism nuclear importGO:190259330.041
cellular component morphogenesisGO:00329893360.040
cell morphogenesisGO:00009022890.040
tube morphogenesisGO:00352393490.039
establishment of endothelial barrierGO:006102830.039
neuron projection developmentGO:00311751800.039
nucleocytoplasmic transportGO:000691340.038
cell motilityGO:00488702440.038
digestive system developmentGO:00551232890.037
nuclear transportGO:005116940.037
blood vessel morphogenesisGO:00485142160.037
regulation of establishment of protein localizationGO:007020140.036
stem cell maintenanceGO:001982740.036
multicellular organism growthGO:003526440.036
transportGO:00068102200.035
immune system processGO:00023762410.035
cell migrationGO:00164772370.034
proteolysis involved in cellular protein catabolic processGO:005160330.034
system processGO:00030081850.034
cellular response to external stimulusGO:007149620.033
cellular macromolecule metabolic processGO:00442603910.033
digestive tract developmentGO:00485652650.033
pole plasm assemblyGO:000731540.032
striated muscle tissue developmentGO:00147061100.032
cellular protein catabolic processGO:004425740.032
actin polymerization or depolymerizationGO:000815420.032
vasculature developmentGO:00019442780.031
regulation of cell projection assemblyGO:006049140.031
establishment of synaptic vesicle localizationGO:009748010.031
oocyte anterior posterior axis specificationGO:000731440.031
nuclear importGO:005117030.030
guanosine containing compound catabolic processGO:190106920.030
g1 s transition of mitotic cell cycleGO:000008210.029
cell morphogenesis involved in differentiationGO:00009041950.029
digestive tract morphogenesisGO:00485462310.029
phagocytosisGO:000690930.029
stem cell proliferationGO:007208940.029
cell agingGO:000756920.029
regulation of signal transductionGO:00099662250.029
regulation of reproductive processGO:200024140.029
meiotic cell cycle processGO:190304630.029
purine nucleoside monophosphate catabolic processGO:000912840.028
angiogenesisGO:00015251580.028
regulation of protein transportGO:005122330.028
nitrogen compound metabolic processGO:00068073190.028
rna localizationGO:000640340.028
cytokinetic processGO:003250620.028
protein polymerizationGO:005125840.028
golgi vesicle transportGO:004819330.027
peptidyl serine phosphorylationGO:001810510.027
single organism metabolic processGO:00447102170.027
heterocycle metabolic processGO:00464832900.027
regulation of cytoplasmic transportGO:190364940.027
gastrulationGO:00073692080.027
meiotic nuclear divisionGO:000712640.027
cell deathGO:00082191210.027
regulation of metabolic processGO:00192223590.027
modification dependent macromolecule catabolic processGO:004363230.027
cellular localizationGO:0051641970.027
regulation of cell differentiationGO:00455951420.027
actin filament based processGO:0030029640.027
gtp metabolic processGO:004603940.026
establishment of protein localization to organelleGO:007259440.026
purine ribonucleoside monophosphate catabolic processGO:000916940.026
regulation of oocyte developmentGO:006028130.026
stem cell divisionGO:001714510.026
rna metabolic processGO:00160702190.026
macromolecule localizationGO:0033036540.026
regulation of intracellular protein transportGO:003315730.026
atp catabolic processGO:000620040.026
regulation of myotube differentiationGO:001083020.026
regulation of developmental processGO:00507932470.026
regulation of primary metabolic processGO:00800903110.026
cell cycle g1 s phase transitionGO:004484310.026
regulation of peptidyl tyrosine phosphorylationGO:005073010.026
regulation of protein import into nucleusGO:004230620.025
regulation of cell shapeGO:000836010.025
ribonucleoside monophosphate catabolic processGO:000915840.025
exocytosisGO:000688710.025
negative regulation of protein phosphorylationGO:000193340.025
cell part morphogenesisGO:00329902460.025
regulation of protein polymerizationGO:003227120.025
cellular response to molecule of bacterial originGO:007121930.025
kidney developmentGO:0001822920.025
neurotransmitter transportGO:000683620.025
regulation of synaptic growth at neuromuscular junctionGO:000858210.025
long chain fatty acid metabolic processGO:000167610.025
synaptic growth at neuromuscular junctionGO:005112420.025
regulation of multicellular organismal processGO:00512392770.024
regulation of gene expressionGO:00104682650.024
cell proliferationGO:0008283800.024
chordate embryonic developmentGO:00430092710.024
regulation of sodium ion transportGO:000202820.024
organonitrogen compound metabolic processGO:1901564740.024
organic cyclic compound metabolic processGO:19013603010.024
maternal determination of anterior posterior axis embryoGO:000835840.024
cellular amine metabolic processGO:004410620.024
embryonic organ morphogenesisGO:00485622740.024
peptide transportGO:001583310.024
gtp catabolic processGO:000618420.024
protein importGO:001703830.024
locomotionGO:00400113130.024
regulation of cellular amino acid metabolic processGO:000652100.023
positive regulation of cellular catabolic processGO:003133130.023
cell surface receptor signaling pathwayGO:00071663250.023
response to woundingGO:00096111160.023
cellular nitrogen compound metabolic processGO:00346412900.023
positive regulation of biological processGO:00485182530.023
muscle cell differentiationGO:00426921390.023
regulation of nitrogen compound metabolic processGO:00511712510.023
germ line stem cell maintenanceGO:003071820.023
actin filament polymerizationGO:003004120.022
determination of left right symmetryGO:00073681790.022
actin cytoskeleton organizationGO:0030036630.022
positive regulation of wound healingGO:009030310.022
muscle cell developmentGO:00550011150.022
actin filament based movementGO:003004810.022
organic substance biosynthetic processGO:19015762890.022
morphogenesis of an epitheliumGO:00020093330.022
regulation of wound healingGO:006104120.022
deathGO:00162651210.022
response to organic substanceGO:00100331530.022
ameboidal type cell migrationGO:00016671430.021
anterior posterior pattern specificationGO:00099521520.021
regulation of protein targetingGO:190353320.021
mitotic cytokinesisGO:000028130.021
organelle organizationGO:00069962270.021
single organism organelle organizationGO:19025891990.021
multi organism processGO:00517041340.020
positive regulation of cell cycleGO:004578730.020
regulation of blood pressureGO:000821710.020
response to glucoseGO:000974930.020
response to drugGO:004249330.020
mitochondrion organizationGO:000700540.020
cell morphogenesis involved in neuron differentiationGO:00486671630.020
neurotransmitter secretionGO:000726920.020
regulation of organ growthGO:004662030.020
positive regulation of cellular component biogenesisGO:004408930.020
sphingolipid biosynthetic processGO:003014820.020
negative regulation of cellular processGO:00485232830.020
regulation of protein localization to plasma membraneGO:190307610.019
lymphocyte proliferationGO:004665110.019
cardiac atrium developmentGO:000323040.019
muscle organ developmentGO:00075171010.019
hormone secretionGO:004687920.019
negative regulation of developmental processGO:0051093650.019
positive regulation of protein complex assemblyGO:003133420.019
i kappab kinase nf kappab signalingGO:000724940.019
cellular response to lipopolysaccharideGO:007122230.019
regulation of multicellular organismal developmentGO:20000262230.019
organelle assemblyGO:00709251100.019
positive regulation of epithelial cell proliferationGO:005067910.019
nucleoside monophosphate catabolic processGO:000912540.019
regulation of epithelial cell proliferationGO:005067830.019
striated muscle cell developmentGO:00550021080.019
cilium morphogenesisGO:0060271850.019
nucleobase containing compound metabolic processGO:00061392740.019
oocyte maturationGO:000155640.019
protein complex localizationGO:003150310.019
amine metabolic processGO:000930820.018
response to external stimulusGO:00096052640.018
adherens junction organizationGO:003433240.018
regulation of cellular amine metabolic processGO:003323800.018
response to hormoneGO:0009725480.018
regulation of protein catabolic processGO:004217610.018
ubiquitin dependent protein catabolic processGO:000651130.018
regulation of cellular ketone metabolic processGO:001056570.018
cognitionGO:005089010.018
cellular response to chemical stimulusGO:00708871570.018
stem cell differentiationGO:00488631170.018
regenerationGO:0031099910.018
rna biosynthetic processGO:00327741810.018
regulation of nucleotide catabolic processGO:003081120.018
head developmentGO:00603223030.018
cellular ketone metabolic processGO:0042180110.018
hemopoiesisGO:00300971830.018
cellular protein metabolic processGO:00442671290.017
macromolecular complex disassemblyGO:003298410.017
regulation of purine nucleotide catabolic processGO:003312120.017
regulation of macromolecule metabolic processGO:00602553170.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
regulation of protein complex assemblyGO:004325430.017
negative regulation of synapse assemblyGO:005196420.017
phosphate containing compound metabolic processGO:00067961080.017
regulation of transportGO:0051049450.017
pathway restricted smad protein phosphorylationGO:006038910.017
cellular amino acid metabolic processGO:000652070.017
neuron projection morphogenesisGO:00488121610.017
circulatory system processGO:0003013870.017
determination of bilateral symmetryGO:00098552040.017
compound eye developmentGO:004874920.017
regulation of neurotransmitter transportGO:005158810.017
cell fate commitmentGO:0045165990.017
regulation of erk1 and erk2 cascadeGO:007037240.017
extrinsic apoptotic signaling pathwayGO:009719130.017
carboxylic acid metabolic processGO:0019752220.017
autophagyGO:000691440.017
positive regulation of secretionGO:005104710.017
cytoplasm organizationGO:000702840.017
phosphorus metabolic processGO:00067931090.017
lipid homeostasisGO:005508830.016
gene expressionGO:00104672520.016
cell projection assemblyGO:0030031640.016
epithelial cell differentiationGO:00308551160.016
enzyme linked receptor protein signaling pathwayGO:00071671060.016
pericardium developmentGO:006003910.016
proteasomal protein catabolic processGO:001049820.016
neurological system processGO:0050877620.016
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.016
protein complex disassemblyGO:004324110.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
cellular component disassemblyGO:002241110.016
glial cell migrationGO:000834730.016
positive regulation of cellular amine metabolic processGO:003324000.016
cellular response to nutrient levelsGO:003166920.016
cellular response to extracellular stimulusGO:003166820.016
response to nutrientGO:000758430.016
g protein coupled receptor signaling pathwayGO:0007186740.016
regulation of blood vessel sizeGO:005088020.015
melanosome transportGO:0032402190.015
regulation of localizationGO:00328791040.015
carbohydrate homeostasisGO:003350010.015
apical junction assemblyGO:004329710.015
protein metabolic processGO:00195381830.015
regulation of cytokine productionGO:000181730.015
intracellular mrna localizationGO:000829810.015
positive regulation of striated muscle cell differentiationGO:005115510.015
fatty acid elongation unsaturated fatty acidGO:001936810.015
regulation of filopodium assemblyGO:005148920.015
actin mediated cell contractionGO:007025210.015
neuroblast proliferationGO:000740520.015
cytoskeleton organizationGO:0007010960.015
regulation of muscle contractionGO:000693730.015
erk1 and erk2 cascadeGO:007037140.015
lateral inhibitionGO:004633110.015
multicellular organismal metabolic processGO:004423620.015
leukocyte proliferationGO:007066110.015
transcription dna templatedGO:00063511810.015
regulation of cell activationGO:005086510.015
nucleic acid templated transcriptionGO:00976591810.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.015
regulation of gtpase activityGO:004308720.015
response to hexoseGO:000974630.015
cilium organizationGO:0044782710.015
nuclear migrationGO:000709730.014
response to carbohydrateGO:000974330.014
immune system developmentGO:00025201910.014
cellular response to organic substanceGO:00713101050.014
regulation of protein localization to nucleusGO:190018020.014
cellular response to biotic stimulusGO:007121630.014
negative regulation of muscle tissue developmentGO:190186220.014
regulation of hormone secretionGO:004688320.014
monoamine transportGO:001584410.014
growthGO:00400071740.014
cellular monovalent inorganic cation homeostasisGO:003000420.014
wound healingGO:0042060900.014
odontogenesis of dentin containing toothGO:004247510.014
small molecule metabolic processGO:0044281770.014
positive regulation of secretion by cellGO:190353210.014
positive regulation of muscle organ developmentGO:004863610.014
establishment of localization in cellGO:0051649770.014
regulation of inflammatory responseGO:005072720.014
positive regulation of protein polymerizationGO:003227320.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
heart morphogenesisGO:00030071560.014
regulation of establishment of planar polarityGO:009017540.014
cellular biosynthetic processGO:00442492860.014
regulation of nucleoside metabolic processGO:000911820.014
regulation of dendrite developmentGO:005077330.014
regulation of cardiac muscle tissue developmentGO:005502410.014
protein homooligomerizationGO:005126030.014
cellular aromatic compound metabolic processGO:00067252950.014
cell junction maintenanceGO:003433120.014
negative regulation of signalingGO:0023057960.014
gastrulation with mouth forming secondGO:0001702440.013
positive regulation of i kappab kinase nf kappab signalingGO:004312330.013
negative regulation of secretion by cellGO:190353120.013
specification of symmetryGO:00097992040.013
receptor recyclingGO:000188140.013
negative regulation of reproductive processGO:200024230.013
establishment of blood brain barrierGO:006085620.013
negative regulation of cell differentiationGO:0045596460.013
somite developmentGO:0061053960.013
b cell activationGO:004211320.013
modification dependent protein catabolic processGO:001994130.013
negative regulation of intracellular protein transportGO:009031730.013
synaptic vesicle transportGO:004848910.013
cilium assemblyGO:0042384580.013
negative regulation of secretionGO:005104820.013
synaptic vesicle localizationGO:009747910.013
regulation of cellular carbohydrate metabolic processGO:001067540.013
adherens junction maintenanceGO:003433420.013
developmental growthGO:00485891660.013
positive regulation of carbohydrate metabolic processGO:004591310.013
positive regulation of metabolic processGO:00098931080.013
organic acid metabolic processGO:0006082310.013
convergent extensionGO:00600261180.013
heart contractionGO:0060047710.013
positive regulation of cellular carbohydrate metabolic processGO:001067610.013
apoptotic process involved in developmentGO:190274220.013
segmentationGO:0035282970.013
taxisGO:00423301090.013
response to other organismGO:0051707970.013
renal system developmentGO:0072001940.012
nucleic acid metabolic processGO:00903042440.012
regulation of receptor mediated endocytosisGO:004825940.012
response to stressGO:00069502630.012
establishment of melanosome localizationGO:0032401190.012
regulation of cell projection organizationGO:0031344440.012
regulation of exocytosisGO:001715710.012
heart processGO:0003015710.012
positive regulation of blood circulationGO:190352420.012
regulation of neurotransmitter secretionGO:004692810.012
regulation of transmembrane transporter activityGO:002289820.012
oxoacid metabolic processGO:0043436310.012
pigment granule transportGO:0051904190.012
secondary metabolic processGO:001974830.012
positive regulation of cytokine productionGO:000181920.012
regulation of establishment of protein localization to plasma membraneGO:009000310.012
epithelial cell developmentGO:0002064420.012
embryonic organ developmentGO:00485683810.012
central nervous system developmentGO:00074173870.012
positive regulation of nucleoside metabolic processGO:004597910.012
intracellular transportGO:0046907320.012
organic substance transportGO:0071702580.012
epithelial cell morphogenesisGO:000338220.012
cellular protein complex assemblyGO:0043623190.012
negative regulation of protein kinase activityGO:000646940.012
positive regulation of cytoskeleton organizationGO:005149530.012
negative regulation of cell communicationGO:0010648960.012
homeostatic processGO:00425921420.012
protein dephosphorylationGO:000647030.012
nucleobase containing compound transportGO:001593120.012
phosphorylationGO:0016310690.012
mitotic cell cycleGO:0000278640.012
behaviorGO:0007610740.012
glucose importGO:004632320.012
response to monosaccharideGO:003428430.012
epibolyGO:0090504410.011
urogenital system developmentGO:0001655970.011
cellular component maintenanceGO:004395430.011
pancreas developmentGO:0031016840.011
positive regulation of camp biosynthetic processGO:003081920.011
aromatic compound biosynthetic processGO:00194382170.011
regulation of carbohydrate metabolic processGO:000610940.011
regulation of signalingGO:00230512350.011
nitric oxide metabolic processGO:004620920.011
peptidyl threonine phosphorylationGO:001810710.011
positive regulation of lipid metabolic processGO:004583410.011
negative regulation of striated muscle tissue developmentGO:004584320.011
regulation of postsynaptic membrane potentialGO:006007810.011
striated muscle cell differentiationGO:00511461290.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
regulation of protein ubiquitinationGO:003139630.011
negative regulation of intracellular transportGO:003238730.011
response to fluid shear stressGO:003440520.011
cellular lipid metabolic processGO:0044255360.011
regulation of cell deathGO:00109411030.011
cardiac atrium morphogenesisGO:000320920.011
regulation of systemic arterial blood pressureGO:000307310.011
regulation of nervous system developmentGO:0051960900.011
chemosensory behaviorGO:000763510.011
neuron neuron synaptic transmissionGO:000727010.011
positive regulation of cellular processGO:00485222010.011
sarcomere organizationGO:0045214260.011
protein localizationGO:0008104400.011
negative regulation of cytokine productionGO:000181810.011
regulation of growth rateGO:004000910.011
positive regulation of dna templated transcription elongationGO:003278610.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
biosynthetic processGO:00090582940.010
regulation of anatomical structure morphogenesisGO:00226031300.010
regulation of nucleocytoplasmic transportGO:004682220.010
response to lipidGO:0033993600.010
regulation of cellular protein metabolic processGO:0032268520.010
regulation of metal ion transportGO:001095940.010
primary neural tube formationGO:001402010.010
lytic vacuole organizationGO:008017110.010
peptidyl serine modificationGO:001820920.010
regulation of anatomical structure sizeGO:0090066330.010
positive regulation of catabolic processGO:000989640.010
positive regulation of cellular metabolic processGO:0031325940.010
regulation of cellular metabolic processGO:00313233200.010
negative regulation of cytoplasmic transportGO:190365020.010
regulation of skeletal muscle tissue developmentGO:004864140.010
convergent extension involved in gastrulationGO:0060027710.010
regulation of glucose importGO:004632410.010

tpte disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.038
sensory system diseaseDOID:005015500.038
eye and adnexa diseaseDOID:149200.038
eye diseaseDOID:561400.038
disease of anatomical entityDOID:700.038
disease of metabolismDOID:001466700.018
inherited metabolic disorderDOID:65500.018
retinal diseaseDOID:567900.012
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.011
cancerDOID:16200.011