Danio rerio

56 known processes

vmhc

ventricular myosin heavy chain

(Aliases: mg:cb02g011,smyhc3)

vmhc biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
striated muscle cell developmentGO:00550021080.994
striated muscle cell differentiationGO:00511461290.992
muscle cell developmentGO:00550011150.992
myofibril assemblyGO:0030239480.987
cardiac muscle cell differentiationGO:0055007300.981
heart developmentGO:00075073130.975
atrial cardiac myofibril assemblyGO:005500420.965
heart morphogenesisGO:00030071560.963
muscle cell differentiationGO:00426921390.961
heart loopingGO:0001947940.933
ventricular cardiac myofibril assemblyGO:005500540.933
cellular component morphogenesisGO:00329893360.906
cardiac myofibril assemblyGO:005500390.905
heart processGO:0003015710.899
ventricular cardiac muscle cell differentiationGO:005501260.881
embryonic heart tube morphogenesisGO:00031431080.864
cardiac muscle cell developmentGO:0055013200.837
muscle structure developmentGO:00610611960.778
striated muscle tissue developmentGO:00147061100.774
muscle tissue developmentGO:00605371100.767
inorganic cation transmembrane transportGO:0098662500.741
sarcomere organizationGO:0045214260.728
cardiocyte differentiationGO:0035051440.655
cellular component assembly involved in morphogenesisGO:00109271070.648
heart contractionGO:0060047710.646
blood circulationGO:0008015870.623
actomyosin structure organizationGO:0031032530.607
cardiac muscle tissue developmentGO:0048738480.600
single organism organelle organizationGO:19025891990.589
cardiac cell developmentGO:0055006210.583
transmembrane transportGO:00550851200.579
regulation of muscle contractionGO:000693730.578
ventricular cardiac muscle tissue developmentGO:000322930.562
ventricular cardiac muscle tissue morphogenesisGO:005501020.516
atrial cardiac muscle cell developmentGO:005501440.515
embryonic organ developmentGO:00485683810.512
determination of bilateral symmetryGO:00098552040.502
determination of heart left right asymmetryGO:00613711170.485
embryonic heart tube developmentGO:00350501330.464
actin cytoskeleton organizationGO:0030036630.454
muscle system processGO:0003012200.437
system processGO:00030081850.429
tube morphogenesisGO:00352393490.425
positive regulation of blood circulationGO:190352420.422
circulatory system processGO:0003013870.406
regulation of heart contractionGO:0008016320.397
regulation of system processGO:0044057400.397
cellular component assemblyGO:00226071700.394
ventricular cardiac muscle cell developmentGO:005501550.386
nucleoside monophosphate catabolic processGO:000912540.385
positive regulation of heart contractionGO:004582320.377
agingGO:000756820.368
larval developmentGO:000216420.365
cardiac muscle fiber developmentGO:004873930.358
cardiac chamber formationGO:000320740.337
myotube differentiationGO:0014902450.297
skeletal muscle organ developmentGO:0060538780.293
actin filament based processGO:0030029640.270
specification of symmetryGO:00097992040.270
calcium ion importGO:007050940.268
fatty acid oxidationGO:001939510.260
response to abiotic stimulusGO:00096281220.257
epithelial tube morphogenesisGO:00605621480.248
embryo development ending in birth or egg hatchingGO:00097922710.230
muscle contractionGO:0006936180.229
regulation of behaviorGO:0050795240.227
muscle organ developmentGO:00075171010.207
neuron differentiationGO:00301823530.203
regulation of ion transmembrane transportGO:0034765180.196
endocardial cushion morphogenesisGO:000320330.191
response to mechanical stimulusGO:0009612240.189
regulation of blood circulationGO:1903522320.180
organelle assemblyGO:00709251100.179
response to chemicalGO:00422213200.173
embryonic organ morphogenesisGO:00485622740.172
determination of left right symmetryGO:00073681790.168
skeletal muscle tissue developmentGO:0007519670.162
purine nucleoside monophosphate catabolic processGO:000912840.158
ion transmembrane transportGO:0034220910.156
morphogenesis of an epitheliumGO:00020093330.150
lymphoid lineage cell migration into thymusGO:009753540.150
atrial cardiac muscle cell differentiationGO:005501150.147
somatic muscle developmentGO:000752540.145
skeletal muscle thin filament assemblyGO:003024040.142
regulation of multicellular organismal processGO:00512392770.142
regulation of ion transmembrane transporter activityGO:003241220.140
cell projection organizationGO:00300302840.137
negative regulation of heart contractionGO:004582220.127
somite developmentGO:0061053960.119
lipid storageGO:001991510.117
digestive system developmentGO:00551232890.115
cardiac chamber morphogenesisGO:0003206120.113
sequestering of metal ionGO:005123830.112
organelle organizationGO:00069962270.110
fatty acid catabolic processGO:000906210.109
cellular component biogenesisGO:00440851780.108
protein complex biogenesisGO:0070271300.104
cellular response to organic cyclic compoundGO:0071407380.103
atp catabolic processGO:000620040.102
glomerulus vasculature developmentGO:007201220.100
nitrogen compound metabolic processGO:00068073190.099
organic acid catabolic processGO:001605430.099
ribonucleoside monophosphate catabolic processGO:000915840.095
taxisGO:00423301090.094
regulation of response to stimulusGO:00485832690.092
positive regulation of biological processGO:00485182530.091
cellular response to organic substanceGO:00713101050.091
cellular lipid catabolic processGO:004424230.087
regulation of metabolic processGO:00192223590.087
chordate embryonic developmentGO:00430092710.087
metal ion homeostasisGO:0055065260.086
pharyngeal muscle developmentGO:004328240.084
myoblast fusionGO:0007520100.082
organic acid metabolic processGO:0006082310.081
locomotionGO:00400113130.079
cardiac ventricle formationGO:000321110.079
digestive tract developmentGO:00485652650.074
stem cell differentiationGO:00488631170.074
cell part morphogenesisGO:00329902460.071
regulation of transmembrane transporter activityGO:002289820.071
behaviorGO:0007610740.070
positive regulation of nucleoside metabolic processGO:004597910.070
oxoacid metabolic processGO:0043436310.070
positive regulation of nitrogen compound metabolic processGO:0051173690.069
cellular response to chemical stimulusGO:00708871570.069
endocardium formationGO:006021410.068
regulation of metal ion transportGO:001095940.068
response to lipidGO:0033993600.066
cardiac ventricle morphogenesisGO:000320870.065
homeostasis of number of cellsGO:0048872620.065
response to topologically incorrect proteinGO:003596620.064
heart field specificationGO:000312810.064
endocardial cushion formationGO:000327220.063
small molecule catabolic processGO:004428230.063
mesenchyme developmentGO:00604851270.063
single organism metabolic processGO:00447102170.062
striated muscle myosin thick filament assemblyGO:007168860.062
cellular protein complex assemblyGO:0043623190.061
er nucleus signaling pathwayGO:000698420.061
response to external stimulusGO:00096052640.061
regulation of purine nucleotide catabolic processGO:003312120.061
cellular response to unfolded proteinGO:003462020.061
cellular biosynthetic processGO:00442492860.061
atrial ventricular junction remodelingGO:000329420.060
myosin filament organizationGO:003103360.057
regulation of membrane repolarizationGO:006030610.056
cell motilityGO:00488702440.055
cardiac conduction system developmentGO:000316110.055
homeostatic processGO:00425921420.054
vasculature developmentGO:00019442780.053
cellular aromatic compound metabolic processGO:00067252950.053
cell projection morphogenesisGO:00488582440.053
pericardium developmentGO:006003910.053
cellular response to external stimulusGO:007149620.053
neuron projection morphogenesisGO:00488121610.053
muscle fiber developmentGO:0048747520.052
central nervous system developmentGO:00074173870.052
cation transportGO:0006812810.051
fluid transportGO:0042044170.051
carboxylic acid metabolic processGO:0019752220.051
mesenchymal cell differentiationGO:0048762870.050
regulation of transmembrane transportGO:0034762180.050
regulation of nitrogen compound metabolic processGO:00511712510.049
organic cyclic compound metabolic processGO:19013603010.049
response to unfolded proteinGO:000698620.049
lipid catabolic processGO:001604240.049
cardiac atrium morphogenesisGO:000320920.048
iron ion homeostasisGO:005507240.046
inorganic ion transmembrane transportGO:0098660570.046
stem cell proliferationGO:007208940.045
regulation of sarcomere organizationGO:006029720.045
cytokinesisGO:000091030.045
heart joggingGO:0003146400.044
regulation of nucleoside metabolic processGO:000911820.043
single organism biosynthetic processGO:0044711710.043
regulation of sequestering of calcium ionGO:005128240.043
maintenance of locationGO:005123540.043
regulation of myotube differentiationGO:001083020.042
organic substance biosynthetic processGO:19015762890.042
cardiac muscle contractionGO:006004860.042
regulation of cell proliferation involved in heart morphogenesisGO:200013620.042
ion homeostasisGO:0050801410.041
head developmentGO:00603223030.041
myosin filament assemblyGO:003103460.040
development of primary female sexual characteristicsGO:004654540.040
response to oxygen containing compoundGO:1901700550.040
regulation of biosynthetic processGO:00098892500.039
negative regulation of biological processGO:00485193040.039
cellular response to topologically incorrect proteinGO:003596720.039
lipid biosynthetic processGO:0008610220.039
regulation of heart growthGO:006042020.039
adult behaviorGO:003053420.038
cardiac ventricle developmentGO:000323190.037
response to stressGO:00069502630.037
macromolecular complex subunit organizationGO:0043933740.037
cardiac atrium developmentGO:000323040.037
lipid oxidationGO:003444010.036
regulation of transporter activityGO:003240920.035
positive regulation of cellular metabolic processGO:0031325940.035
regulation of cardiac muscle contractionGO:005511720.035
atrioventricular valve morphogenesisGO:000318160.035
atrioventricular valve formationGO:000319030.035
regulation of heart morphogenesisGO:2000826170.035
regulation of nucleic acid templated transcriptionGO:19035062130.034
response to corticosteroidGO:003196010.034
response to glucocorticoidGO:005138410.034
nucleic acid templated transcriptionGO:00976591810.034
positive regulation of cytosolic calcium ion concentrationGO:000720440.034
cellular response to lipidGO:0071396390.034
cation transmembrane transportGO:0098655650.034
positive regulation of transportGO:005105020.033
metal ion transportGO:0030001580.033
dendrite guidanceGO:007098300.033
negative regulation of striated muscle tissue developmentGO:004584320.033
regulation of localizationGO:00328791040.033
lymphoid lineage cell migrationGO:009753440.033
organonitrogen compound metabolic processGO:1901564740.033
ion transportGO:00068111140.033
membrane repolarizationGO:008600920.033
regulation of cytokine productionGO:000181730.032
negative regulation of protein phosphorylationGO:000193340.032
eye developmentGO:00016542770.032
olfactory bulb axon guidanceGO:007167830.032
regulation of striated muscle contractionGO:000694220.031
regulation of cell communicationGO:00106462320.031
renal system developmentGO:0072001940.031
response to bacteriumGO:0009617580.031
intermediate mesoderm developmentGO:004838920.030
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.030
outflow tract morphogenesisGO:000315110.030
axonogenesisGO:00074091520.029
skeletal muscle fiber developmentGO:0048741350.029
positive regulation of transcription dna templatedGO:0045893570.029
neuron developmentGO:00486662620.029
nucleobase containing compound biosynthetic processGO:00346542050.029
endocardial cushion developmentGO:000319760.029
actin filament based movementGO:003004810.029
cell morphogenesis involved in differentiationGO:00009041950.029
positive regulation of cytokine productionGO:000181920.029
heart valve morphogenesisGO:000317980.028
axis elongationGO:0003401310.028
cellular response to stressGO:0033554620.028
pathway restricted smad protein phosphorylationGO:006038910.028
brain developmentGO:00074202930.028
sequestering of calcium ionGO:005120830.027
collagen metabolic processGO:003296320.027
regulation of circadian rhythmGO:004275240.027
regulation of apoptotic processGO:0042981980.027
regulation of biological qualityGO:00650082630.027
digestive tract morphogenesisGO:00485462310.027
cellular protein metabolic processGO:00442671290.027
regulation of cardiac muscle tissue developmentGO:005502410.026
regulation of calcium ion transportGO:005192420.026
regulation of skeletal muscle fiber developmentGO:004874220.026
regulation of anatomical structure morphogenesisGO:00226031300.026
endoplasmic reticulum unfolded protein responseGO:003096820.026
organic cyclic compound biosynthetic processGO:19013622230.026
regulation of bindingGO:005109830.026
striated muscle contractionGO:0006941120.026
retina morphogenesis in camera type eyeGO:0060042790.026
positive regulation of rna biosynthetic processGO:1902680570.026
nucleic acid metabolic processGO:00903042440.026
cytoskeleton organizationGO:0007010960.026
kidney vasculature developmentGO:006144020.026
phosphate containing compound metabolic processGO:00067961080.025
cell death in response to oxidative stressGO:003647320.025
regulation of nucleotide catabolic processGO:003081120.025
regulation of muscle system processGO:009025750.025
convergent extensionGO:00600261180.025
negative regulation of muscle tissue developmentGO:190186220.025
response to hormoneGO:0009725480.024
pronephros developmentGO:0048793690.024
regulation of multicellular organismal developmentGO:20000262230.024
cell surface receptor signaling pathwayGO:00071663250.024
gastrulationGO:00073692080.024
cell morphogenesis involved in neuron differentiationGO:00486671630.024
cell migrationGO:00164772370.024
divalent inorganic cation homeostasisGO:0072507220.024
phosphorus metabolic processGO:00067931090.024
cytosolic calcium ion transportGO:006040130.024
anterior posterior pattern specificationGO:00099521520.023
regulation of locomotionGO:0040012550.023
cation homeostasisGO:0055080330.023
regulation of signalingGO:00230512350.023
stem cell divisionGO:001714510.023
monocarboxylic acid catabolic processGO:007232930.023
positive regulation of cellular catabolic processGO:003133130.023
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.023
cardiogenic plate morphogenesisGO:000314210.023
lymphocyte homeostasisGO:000226010.023
cellular component movementGO:00069283350.023
circadian sleep wake cycleGO:004274520.023
mesenchymal cell developmentGO:0014031780.023
carboxylic acid catabolic processGO:004639530.023
biomineral tissue developmentGO:0031214130.022
cardiac muscle cell contractionGO:008600310.022
somitogenesisGO:0001756870.022
cell morphogenesisGO:00009022890.022
sarcomerogenesisGO:004876940.022
positive regulation of cell adhesionGO:004578510.022
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.022
cardiac chamber developmentGO:0003205190.022
female sex differentiationGO:004666040.022
mesoderm formationGO:0001707430.021
b cell activationGO:004211320.021
regulation of cell migrationGO:0030334400.021
cranial suture morphogenesisGO:006036310.021
positive regulation of skeletal muscle tissue developmentGO:004864310.021
apoptotic processGO:00069151160.021
cellular ion homeostasisGO:0006873170.021
cellular amino acid biosynthetic processGO:000865220.021
regulation of stem cell differentiationGO:200073640.021
axon developmentGO:00615641660.021
embryonic cranial skeleton morphogenesisGO:0048701900.021
response to organic substanceGO:00100331530.020
multicellular organismal reproductive processGO:0048609350.020
localization of cellGO:00516742440.020
catechol containing compound metabolic processGO:000971220.020
positive regulation of purine nucleotide catabolic processGO:003312310.020
rna metabolic processGO:00160702190.020
response to ketoneGO:190165410.020
regionalizationGO:00030022740.020
biosynthetic processGO:00090582940.020
reproductionGO:0000003400.020
positive regulation of stem cell proliferationGO:200064810.020
cardiac muscle tissue morphogenesisGO:005500870.019
cellular response to nutrient levelsGO:003166920.019
cellular amino acid metabolic processGO:000652070.019
anatomical structure homeostasisGO:0060249360.019
myotube cell developmentGO:0014904350.019
tissue remodelingGO:004877140.019
positive regulation of striated muscle cell differentiationGO:005115510.019
negative regulation of kinase activityGO:003367340.019
positive regulation of macrophage chemotaxisGO:001075910.019
cellular aldehyde metabolic processGO:000608140.019
regulation of i kappab kinase nf kappab signalingGO:004312240.018
intracellular mrna localizationGO:000829810.018
regulation of jak stat cascadeGO:004642530.018
immune system processGO:00023762410.018
renal system vasculature developmentGO:006143720.018
cell migration involved in heart formationGO:0060974100.018
generation of neuronsGO:00486993850.018
response to steroid hormoneGO:0048545350.018
regulation of cellular biosynthetic processGO:00313262450.018
protein metabolic processGO:00195381830.018
negative regulation of programmed cell deathGO:0043069580.018
positive regulation of striated muscle tissue developmentGO:004584410.018
circadian sleep wake cycle sleepGO:005080210.017
negative regulation of cellular processGO:00485232830.017
regulation of protein complex assemblyGO:004325430.017
positive regulation of muscle cell differentiationGO:005114910.017
epithelial to mesenchymal transitionGO:0001837210.017
calcium ion transport into cytosolGO:006040230.017
regulation of protein localization to nucleusGO:190018020.017
small molecule metabolic processGO:0044281770.017
negative regulation of blood circulationGO:190352320.017
diencephalon developmentGO:0021536580.017
cell substrate adhesionGO:003158940.016
rna biosynthetic processGO:00327741810.016
water homeostasisGO:003010440.016
cell proliferation involved in heart morphogenesisGO:006132320.016
positive regulation of nucleotide catabolic processGO:003081310.016
cellular response to hormone stimulusGO:0032870390.016
regulation of cell shapeGO:000836010.016
cellular response to oxygen containing compoundGO:1901701200.016
regulation of protein import into nucleusGO:004230620.016
neuron projection developmentGO:00311751800.016
gene expressionGO:00104672520.015
purine ribonucleoside monophosphate catabolic processGO:000916940.015
cranial nerve developmentGO:0021545420.015
catecholamine metabolic processGO:000658420.015
nerve developmentGO:0021675450.015
macromolecule biosynthetic processGO:00090592270.015
regulation of epithelial to mesenchymal transitionGO:001071730.015
glucocorticoid metabolic processGO:000821120.015
growthGO:00400071740.015
heart valve formationGO:000318840.015
sensory system developmentGO:0048880760.015
muscle organ morphogenesisGO:004864480.015
intracellular signal transductionGO:0035556850.015
regulation of protein bindingGO:004339330.015
regulation of cell motilityGO:2000145460.015
positive regulation of metabolic processGO:00098931080.015
regulation of bone mineralizationGO:003050020.015
positive regulation of epithelial cell migrationGO:001063420.014
regulation of membrane potentialGO:0042391230.014
divalent metal ion transportGO:0070838200.014
divalent inorganic cation transportGO:0072511210.014
transcription from rna polymerase ii promoterGO:0006366800.014
lipid metabolic processGO:0006629520.014
chemotaxisGO:00069351040.014
feeding behaviorGO:000763150.014
response to organic cyclic compoundGO:0014070510.014
response to endogenous stimulusGO:0009719830.014
glutamate receptor signaling pathwayGO:000721510.014
olfactory lobe developmentGO:002198840.014
heart valve developmentGO:0003170140.014
nephron tubule epithelial cell differentiationGO:007216010.014
regulation of cellular component movementGO:0051270550.014
transcription dna templatedGO:00063511810.014
positive regulation of nucleobase containing compound metabolic processGO:0045935690.014
neurotransmitter secretionGO:000726920.014
ovarian follicle developmentGO:000154120.014
sensory organ developmentGO:00074233930.014
neurotransmitter transportGO:000683620.014
embryonic skeletal joint morphogenesisGO:006027230.014
regulation of cellular component organizationGO:0051128860.014
pole plasm assemblyGO:000731540.014
circadian sleep wake cycle processGO:002241020.014
protein polymerizationGO:005125840.014
intestinal cholesterol absorptionGO:003029920.014
regulation of cell substrate adhesionGO:001081010.013
oocyte developmentGO:0048599140.013
signal transduction in absence of ligandGO:003803410.013
positive regulation of cellular processGO:00485222010.013
heterocycle metabolic processGO:00464832900.013
regulation of cell developmentGO:00602841000.013
sex determinationGO:000753010.013
myeloid cell homeostasisGO:0002262560.013
negative regulation of cytokine productionGO:000181810.013
protein complex subunit organizationGO:0071822460.013
negative regulation of epithelial cell proliferationGO:005068010.013
muscle tissue morphogenesisGO:006041570.013
regulation of actin filament based processGO:003297090.013
directional locomotionGO:003305810.013
action potentialGO:0001508190.013
regulation of transportGO:0051049450.013
trabecula formationGO:006034320.013
regulation of macromolecule biosynthetic processGO:00105562250.013
regulation of cell differentiationGO:00455951420.013
cardiac conductionGO:006133730.013
autophagyGO:000691440.013
establishment of localizationGO:00512342440.013
hormone biosynthetic processGO:004244630.013
blood vessel developmentGO:00015682460.013
positive regulation of muscle tissue developmentGO:190186310.013
extracellular matrix organizationGO:0030198270.013
regulation of neurotransmitter secretionGO:004692810.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
positive regulation of biosynthetic processGO:0009891680.012
positive regulation of map kinase activityGO:004340630.012
angiogenesisGO:00015251580.012
response to hydrogen peroxideGO:004254230.012
establishment of protein localization to organelleGO:007259440.012
multicellular organismal macromolecule metabolic processGO:004425920.012
regulation of epithelial cell proliferationGO:005067830.012
syncytium formationGO:0006949120.012
cell cell adhesion involved in mesendodermal cell migrationGO:000337010.012
regulation of erythrocyte differentiationGO:004564620.012
cellular macromolecule metabolic processGO:00442603910.012
regulation of cellular amino acid metabolic processGO:000652100.012
positive regulation of muscle organ developmentGO:004863610.012
response to dexamethasoneGO:007154810.012
response to carbohydrateGO:000974330.012
response to nutrientGO:000758430.012
camera type eye morphogenesisGO:00485931080.012
regulation of cell deathGO:00109411030.012
establishment of monopolar cell polarityGO:006116220.012
negative regulation of mesodermal cell fate specificationGO:004266230.012
syncytium formation by plasma membrane fusionGO:0000768120.012
regulation of cardiac muscle cell differentiationGO:200072510.011
axis specificationGO:0009798430.011
regulation of rac protein signal transductionGO:003502010.011
cell chemotaxisGO:0060326170.011
negative regulation of catabolic processGO:000989530.011
dna catabolic processGO:000630810.011
cartilage condensationGO:000150230.011
urogenital system developmentGO:0001655970.011
axial mesoderm developmentGO:0048318100.011
specification of organ identityGO:001009220.011
cellular calcium ion homeostasisGO:0006874130.011
single organism localizationGO:19025782250.011
oogenesisGO:0048477140.011
negative regulation of apoptotic processGO:0043066550.011
response to heatGO:000940860.011
stem cell maintenanceGO:001982740.011
cellular localizationGO:0051641970.011
regulation of macromolecule metabolic processGO:00602553170.011
skeletal system developmentGO:00015011810.011
cell migration involved in heart developmentGO:0060973220.011
regulation of transcription dna templatedGO:00063552130.011
pronephric duct developmentGO:0039022130.011
response to extracellular stimulusGO:0009991100.011

vmhc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiomyopathyDOID:005070000.668
muscular diseaseDOID:008000000.668
disease of anatomical entityDOID:700.668
heart diseaseDOID:11400.668
cardiovascular system diseaseDOID:128700.668
musculoskeletal system diseaseDOID:1700.668
muscle tissue diseaseDOID:6600.668
myopathyDOID:42300.668
intrinsic cardiomyopathyDOID:006003600.605
hypertrophic cardiomyopathyDOID:1198400.100
dilated cardiomyopathyDOID:1293000.022
disease of metabolismDOID:001466700.016