Danio rerio

0 known processes

spon2b

spondin 2b, extracellular matrix protein

(Aliases: mindin2,etID309958.14,zgc:100756,MGC152813)

spon2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vasculature developmentGO:00019442780.231
cartilage developmentGO:0051216960.213
skeletal system developmentGO:00015011810.193
embryonic organ developmentGO:00485683810.192
notochord developmentGO:0030903540.159
larval developmentGO:000216420.157
negative regulation of biological processGO:00485193040.148
connective tissue developmentGO:0061448990.146
embryo development ending in birth or egg hatchingGO:00097922710.139
embryonic organ morphogenesisGO:00485622740.137
cellular macromolecule metabolic processGO:00442603910.132
blood vessel morphogenesisGO:00485142160.121
generation of neuronsGO:00486993850.109
cellular component movementGO:00069283350.109
cell migrationGO:00164772370.098
morphogenesis of an epitheliumGO:00020093330.089
response to chemicalGO:00422213200.089
Mouse
convergent extensionGO:00600261180.088
neuron differentiationGO:00301823530.085
neuron projection developmentGO:00311751800.078
regulation of synapse organizationGO:005080730.077
sensory organ developmentGO:00074233930.071
negative regulation of cellular processGO:00485232830.070
blood vessel developmentGO:00015682460.069
axonogenesisGO:00074091520.068
muscle structure developmentGO:00610611960.068
sensory organ morphogenesisGO:00905962000.063
cell surface receptor signaling pathwayGO:00071663250.063
regulation of epithelial cell proliferationGO:005067830.061
collagen fibril organizationGO:003019910.061
gene expressionGO:00104672520.059
regulation of metabolic processGO:00192223590.059
regulation of macromolecule metabolic processGO:00602553170.059
digestive tract developmentGO:00485652650.058
nitrogen compound metabolic processGO:00068073190.058
regulation of rna biosynthetic processGO:20011412130.058
response to stressGO:00069502630.057
Mouse
neuron developmentGO:00486662620.056
cell part morphogenesisGO:00329902460.056
positive regulation of epithelial cell differentiationGO:003085820.054
eye morphogenesisGO:00485921440.054
embryonic cranial skeleton morphogenesisGO:0048701900.054
eye developmentGO:00016542770.054
cellular component morphogenesisGO:00329893360.054
heterocycle metabolic processGO:00464832900.053
developmental growthGO:00485891660.053
regulation of synapse assemblyGO:005196330.053
cellular nitrogen compound biosynthetic processGO:00442712180.052
convergent extension involved in gastrulationGO:0060027710.051
regulation of cellular metabolic processGO:00313233200.051
embryonic skeletal system morphogenesisGO:0048704930.050
regulation of signal transductionGO:00099662250.050
regulation of nucleic acid templated transcriptionGO:19035062130.050
digestive tract morphogenesisGO:00485462310.050
regulation of nitrogen compound metabolic processGO:00511712510.049
nucleic acid templated transcriptionGO:00976591810.049
determination of heart left right asymmetryGO:00613711170.049
embryonic skeletal system developmentGO:0048706970.048
neuron projection morphogenesisGO:00488121610.048
negative regulation of response to stimulusGO:00485851040.048
cell projection organizationGO:00300302840.048
gastrulationGO:00073692080.048
rna biosynthetic processGO:00327741810.048
aromatic compound biosynthetic processGO:00194382170.048
digestive system developmentGO:00551232890.047
regulation of multicellular organismal processGO:00512392770.047
Mouse
negative regulation of protein phosphorylationGO:000193340.046
skeletal system morphogenesisGO:00487051020.045
cellular nitrogen compound metabolic processGO:00346412900.045
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.045
cell morphogenesisGO:00009022890.044
regulation of protein catabolic processGO:004217610.044
extracellular structure organizationGO:0043062270.044
oxoacid metabolic processGO:0043436310.044
embryonic viscerocranium morphogenesisGO:0048703520.044
cell projection morphogenesisGO:00488582440.043
ameboidal type cell migrationGO:00016671430.043
regulation of peptidyl tyrosine phosphorylationGO:005073010.043
embryonic camera type eye developmentGO:0031076290.043
extracellular matrix organizationGO:0030198270.042
cellular response to external stimulusGO:007149620.041
agingGO:000756820.041
head developmentGO:00603223030.041
regulation of cell differentiationGO:00455951420.040
chordate embryonic developmentGO:00430092710.040
nucleic acid metabolic processGO:00903042440.039
cellular amino acid metabolic processGO:000652070.039
taxisGO:00423301090.038
cellular aromatic compound metabolic processGO:00067252950.037
maintenance of locationGO:005123540.036
lipid storageGO:001991510.036
tube morphogenesisGO:00352393490.035
camera type eye developmentGO:00430102220.035
negative regulation of cell communicationGO:0010648960.035
angiogenesisGO:00015251580.035
multicellular organism growthGO:003526440.034
rna metabolic processGO:00160702190.034
fin developmentGO:0033333770.034
protein metabolic processGO:00195381830.034
regulation of synaptic growth at neuromuscular junctionGO:000858210.034
regulation of cellular amino acid metabolic processGO:000652100.034
extrinsic apoptotic signaling pathwayGO:009719130.033
signal transductionGO:00071654550.033
regulation of primary metabolic processGO:00800903110.033
organic acid metabolic processGO:0006082310.033
organic cyclic compound biosynthetic processGO:19013622230.033
response to organic substanceGO:00100331530.033
Mouse
nucleoside monophosphate catabolic processGO:000912540.033
phagocytosisGO:000690930.033
Mouse
peptidyl serine phosphorylationGO:001810510.032
somite developmentGO:0061053960.032
regulation of nucleobase containing compound metabolic processGO:00192192500.032
positive regulation of transportGO:005105020.032
cellular response to chemical stimulusGO:00708871570.032
Mouse
cellular component assemblyGO:00226071700.032
response to corticosteroidGO:003196010.032
amine metabolic processGO:000930820.031
cell motilityGO:00488702440.031
positive regulation of cellular processGO:00485222010.031
cellular biosynthetic processGO:00442492860.031
cellular ketone metabolic processGO:0042180110.031
muscle organ developmentGO:00075171010.031
synaptic growth at neuromuscular junctionGO:005112420.030
outflow tract morphogenesisGO:000315110.030
regulation of establishment of protein localizationGO:007020140.030
regulation of biosynthetic processGO:00098892500.030
stem cell differentiationGO:00488631170.030
cellular component biogenesisGO:00440851780.030
regulation of cell communicationGO:00106462320.030
response to drugGO:004249330.030
carboxylic acid metabolic processGO:0019752220.029
epithelial tube morphogenesisGO:00605621480.029
negative regulation of developmental processGO:0051093650.029
enzyme linked receptor protein signaling pathwayGO:00071671060.029
positive regulation of cellular component biogenesisGO:004408930.028
response to abiotic stimulusGO:00096281220.028
non canonical wnt signaling pathway involved in heart developmentGO:006134120.028
purine ribonucleoside monophosphate catabolic processGO:000916940.027
localization of cellGO:00516742440.027
nucleobase containing compound metabolic processGO:00061392740.027
axon developmentGO:00615641660.027
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.027
regulation of cellular amine metabolic processGO:003323800.027
transcription dna templatedGO:00063511810.027
organonitrogen compound metabolic processGO:1901564740.027
regulation of signalingGO:00230512350.027
regulation of cellular ketone metabolic processGO:001056570.027
protein targeting to nucleusGO:004474430.026
regulation of biomineral tissue developmentGO:007016720.026
regulation of response to stimulusGO:00485832690.026
Mouse
regionalizationGO:00030022740.026
negative regulation of metabolic processGO:0009892860.026
regulation of rna metabolic processGO:00512522240.026
positive regulation of cellular amino acid metabolic processGO:004576400.026
sprouting angiogenesisGO:0002040530.026
organic cyclic compound metabolic processGO:19013603010.025
regulation of multicellular organism growthGO:004001440.025
regenerationGO:0031099910.025
brain developmentGO:00074202930.025
positive regulation of cellular amine metabolic processGO:003324000.024
regulation of protein targetingGO:190353320.024
appendage developmentGO:0048736800.024
heart joggingGO:0003146400.024
regulation of extrinsic apoptotic signaling pathwayGO:200123630.024
negative regulation of signal transductionGO:0009968940.024
cellular amine metabolic processGO:004410620.024
negative regulation of signalingGO:0023057960.023
regulation of cell activationGO:005086510.023
heterocycle biosynthetic processGO:00181302150.023
embryonic heart tube developmentGO:00350501330.023
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.023
regulation of macromolecule biosynthetic processGO:00105562250.023
regulation of protein transportGO:005122330.023
neurological system processGO:0050877620.023
adult behaviorGO:003053420.023
regulation of nervous system developmentGO:0051960900.023
ear developmentGO:00435831270.022
camera type eye morphogenesisGO:00485931080.022
embryonic heart tube morphogenesisGO:00031431080.022
peptidyl serine modificationGO:001820920.022
mesoderm developmentGO:0007498880.022
response to hexoseGO:000974630.022
positive regulation of canonical wnt signaling pathwayGO:009026340.022
system processGO:00030081850.022
positive regulation of metabolic processGO:00098931080.022
negative regulation of epithelial cell proliferationGO:005068010.022
cell morphogenesis involved in neuron differentiationGO:00486671630.022
response to monosaccharideGO:003428430.022
proteasomal protein catabolic processGO:001049820.021
nucleobase containing compound biosynthetic processGO:00346542050.021
cell migration involved in gastrulationGO:0042074790.021
regulation of anatomical structure morphogenesisGO:00226031300.021
embryonic eye morphogenesisGO:0048048300.021
stem cell divisionGO:001714510.021
urogenital system developmentGO:0001655970.021
cell morphogenesis involved in differentiationGO:00009041950.021
transcription from rna polymerase ii promoterGO:0006366800.021
cellular macromolecule biosynthetic processGO:00346452240.021
mesenchymal cell differentiationGO:0048762870.021
neurotransmitter transportGO:000683620.021
heart developmentGO:00075073130.021
appendage morphogenesisGO:0035107560.020
positive regulation of epithelial cell proliferationGO:005067910.020
positive regulation of catabolic processGO:000989640.020
tissue regenerationGO:0042246740.020
regulation of cell developmentGO:00602841000.020
regulation of cell shapeGO:000836010.020
melanin metabolic processGO:000658220.020
biosynthetic processGO:00090582940.020
negative regulation of multicellular organismal processGO:0051241690.020
axon guidanceGO:0007411860.020
regulation of transcription dna templatedGO:00063552130.020
response to axon injuryGO:0048678140.020
specification of symmetryGO:00097992040.019
myeloid leukocyte migrationGO:0097529120.019
response to bacteriumGO:0009617580.019
Mouse
membrane invaginationGO:001032410.019
regulation of developmental processGO:00507932470.019
apoptotic processGO:00069151160.019
phosphorylationGO:0016310690.018
cellular response to extracellular stimulusGO:003166820.018
axis elongationGO:0003401310.018
positive regulation of macromolecule biosynthetic processGO:0010557590.018
regulation of protein complex assemblyGO:004325430.018
lipid metabolic processGO:0006629520.018
purine ribonucleoside biosynthetic processGO:004612920.018
glutamate receptor signaling pathwayGO:000721510.018
cortical cytoskeleton organizationGO:003086510.018
regulation of endothelial cell proliferationGO:000193610.018
establishment of blood brain barrierGO:006085620.018
central nervous system developmentGO:00074173870.018
modification dependent protein catabolic processGO:001994130.018
heart morphogenesisGO:00030071560.018
nucleocytoplasmic transportGO:000691340.018
positive regulation of leukocyte chemotaxisGO:000269010.018
macromolecule biosynthetic processGO:00090592270.018
purine nucleoside monophosphate catabolic processGO:000912840.017
gland developmentGO:00487321430.017
regulation of cellular protein metabolic processGO:0032268520.017
protein complex subunit organizationGO:0071822460.017
proteolysis involved in cellular protein catabolic processGO:005160330.017
regulation of localizationGO:00328791040.017
locomotionGO:00400113130.017
wound healingGO:0042060900.017
multicellular organismal metabolic processGO:004423620.017
response to glucocorticoidGO:005138410.017
biomineral tissue developmentGO:0031214130.017
somatic muscle developmentGO:000752540.017
inner ear developmentGO:00488391260.016
regulation of reproductive processGO:200024140.016
establishment of protein localization to organelleGO:007259440.016
endoderm developmentGO:0007492490.016
cell growthGO:0016049570.016
cellular response to stressGO:0033554620.016
cellular response to organic substanceGO:00713101050.016
Mouse
response to woundingGO:00096111160.016
regulation of chondrocyte differentiationGO:003233010.016
pancreas developmentGO:0031016840.016
phosphate containing compound metabolic processGO:00067961080.016
epibolyGO:0090504410.016
nephron epithelium morphogenesisGO:007208810.015
regulation of cell motilityGO:2000145460.015
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.015
neutrophil migrationGO:1990266100.015
lens fiber cell developmentGO:007030730.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
phosphorus metabolic processGO:00067931090.015
ossificationGO:0001503230.015
neural crest cell differentiationGO:0014033720.015
epithelial cell differentiationGO:00308551160.015
regulation of cellular biosynthetic processGO:00313262450.015
regulation of intracellular protein transportGO:003315730.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.015
nuclear transportGO:005116940.015
response to endogenous stimulusGO:0009719830.015
regulation of cell migrationGO:0030334400.015
anterior posterior pattern specificationGO:00099521520.015
protein homooligomerizationGO:005126030.015
positive regulation of biological processGO:00485182530.015
Mouse
macromolecular complex subunit organizationGO:0043933740.015
female gonad developmentGO:000858540.015
developmental growth involved in morphogenesisGO:0060560860.015
protein phosphorylationGO:0006468470.015
organic substance biosynthetic processGO:19015762890.015
positive regulation of cellular metabolic processGO:0031325940.015
neuronal action potentialGO:0019228180.015
modification dependent macromolecule catabolic processGO:004363230.015
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.015
single fertilizationGO:000733830.015
ubiquitin dependent protein catabolic processGO:000651130.015
regulation of organ growthGO:004662030.015
stem cell proliferationGO:007208940.015
growthGO:00400071740.014
proteolysisGO:0006508380.014
convergent extension involved in axis elongationGO:0060028260.014
regulation of cytoplasmic transportGO:190364940.014
negative regulation of feeding behaviorGO:200025220.014
atp catabolic processGO:000620040.014
phagocytosis engulfmentGO:000691110.014
otic vesicle morphogenesisGO:0071600340.014
regulation of gene expressionGO:00104682650.014
cell deathGO:00082191210.014
negative regulation of intracellular transportGO:003238730.014
protein localization to nucleusGO:003450430.014
gtp metabolic processGO:004603940.014
liver developmentGO:0001889960.014
stem cell developmentGO:0048864820.014
response to unfolded proteinGO:000698620.014
positive regulation of chemotaxisGO:005092150.014
negative regulation of reproductive processGO:200024230.014
phototransductionGO:000760220.014
formation of primary germ layerGO:0001704620.014
wnt signaling pathwayGO:0016055800.014
action potentialGO:0001508190.013
positive regulation of cell divisionGO:005178120.013
skin developmentGO:0043588540.013
positive regulation of cellular catabolic processGO:003133130.013
regulation of neutrophil migrationGO:190262260.013
negative chemotaxisGO:005091910.013
cortical actin cytoskeleton organizationGO:003086610.013
ribonucleoside monophosphate catabolic processGO:000915840.013
negative regulation of cell differentiationGO:0045596460.013
determination of bilateral symmetryGO:00098552040.013
regulation of biological qualityGO:00650082630.013
mesenchymal cell developmentGO:0014031780.013
positive regulation of gene expressionGO:0010628710.013
oocyte maturationGO:000155640.013
response to vitaminGO:003327330.013
negative regulation of cytoplasmic transportGO:190365020.013
response to amino acidGO:004320020.013
regulation of stem cell differentiationGO:200073640.013
lipid catabolic processGO:001604240.013
mitochondrion organizationGO:000700540.013
response to uvGO:000941130.013
small molecule metabolic processGO:0044281770.013
cellular response to endogenous stimulusGO:0071495680.013
positive regulation of macromolecule metabolic processGO:0010604930.013
immune system developmentGO:00025201910.013
single organism metabolic processGO:00447102170.013
positive regulation of protein complex assemblyGO:003133420.013
muscle cell differentiationGO:00426921390.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.012
positive regulation of leukocyte migrationGO:000268720.012
negative regulation of synapse assemblyGO:005196420.012
response to ketoneGO:190165410.012
apoptotic process involved in developmentGO:190274220.012
mesenchyme developmentGO:00604851270.012
central nervous system neuron differentiationGO:0021953740.012
regulation of cellular protein catabolic processGO:190336210.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
protein dephosphorylationGO:000647030.012
extracellular matrix assemblyGO:008502910.012
fin morphogenesisGO:0033334530.012
hard palate developmentGO:006002240.012
muscle fiber developmentGO:0048747520.012
regulation of erk1 and erk2 cascadeGO:007037240.012
regulation of nucleocytoplasmic transportGO:004682220.012
gtp catabolic processGO:000618420.012
tissue remodelingGO:004877140.012
chemotaxisGO:00069351040.012
energy reserve metabolic processGO:000611220.012
transportGO:00068102200.012
Mouse
regulation of protein ubiquitinationGO:003139630.012
positive regulation of endothelial cell proliferationGO:000193810.012
negative regulation of macromolecule metabolic processGO:0010605760.012
positive regulation of transcription dna templatedGO:0045893570.012
neuron projection extensionGO:1990138450.012
cellular component assembly involved in morphogenesisGO:00109271070.012
carbohydrate derivative metabolic processGO:1901135610.012
embryonic camera type eye morphogenesisGO:0048596190.012
neuron projection guidanceGO:0097485860.012
regulation of peptidase activityGO:0052547230.012
response to hormoneGO:0009725480.012
cellular carbohydrate metabolic processGO:004426240.011
sequestering of calcium ionGO:005120830.011
response to topologically incorrect proteinGO:003596620.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.011
regulation of membrane potentialGO:0042391230.011
peptidyl threonine phosphorylationGO:001810710.011
cell fate commitmentGO:0045165990.011
negative regulation of gene expressionGO:0010629650.011
zymogen activationGO:003163830.011
regulation of oocyte developmentGO:006028130.011
cell substrate adhesionGO:003158940.011
regulation of sequestering of calcium ionGO:005128240.011
regulation of metal ion transportGO:001095940.011
striated muscle cell developmentGO:00550021080.011
striated muscle tissue developmentGO:00147061100.011
regulation of stem cell proliferationGO:007209120.011
collagen metabolic processGO:003296320.011
nuclear migrationGO:000709730.011
lateral inhibitionGO:004633110.011
regulation of ion transmembrane transporter activityGO:003241220.011
protein targeting to membraneGO:000661210.011
regulation of multicellular organismal developmentGO:20000262230.011
negative regulation of wnt signaling pathwayGO:0030178300.011
negative regulation of kinase activityGO:003367340.011
regulation of apoptotic processGO:0042981980.011
pronephros morphogenesisGO:0072114140.011
negative regulation of dna metabolic processGO:005105340.011
tube closureGO:006060610.011
positive regulation of lipid metabolic processGO:004583410.011
cellular protein catabolic processGO:004425740.011
gliogenesisGO:0042063450.011
aminoglycan metabolic processGO:000602290.011
regulation of bmp signaling pathwayGO:0030510390.011
production of molecular mediator of immune responseGO:000244020.011
Mouse
negative regulation of gastrulationGO:2000542110.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
female sex differentiationGO:004666040.011
regulation of sodium ion transportGO:000202820.011
calcium ion importGO:007050940.011
homeostatic processGO:00425921420.011
monocarboxylic acid catabolic processGO:007232930.011
cell projection assemblyGO:0030031640.011
regulation of wound healingGO:006104120.011
ectodermal placode morphogenesisGO:0071697320.011
peptidyl threonine modificationGO:001821010.011
optic placode formationGO:000174340.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
deathGO:00162651210.011
notochord morphogenesisGO:0048570170.011
water homeostasisGO:003010440.011
axon extensionGO:0048675450.011
guanosine containing compound metabolic processGO:190106840.011
negative regulation of protein import into nucleusGO:004230820.011
regulation of protein import into nucleusGO:004230620.010
positive regulation of neutrophil migrationGO:190262400.010
cellular lipid catabolic processGO:004424230.010
smad protein complex assemblyGO:000718310.010
establishment of organelle localizationGO:0051656450.010
hemopoiesisGO:00300971830.010
positive regulation of rna biosynthetic processGO:1902680570.010
exocytosisGO:000688710.010
regulation of neural precursor cell proliferationGO:200017730.010
nuclear exportGO:005116810.010
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.010
nerve developmentGO:0021675450.010
optic placode formation involved in camera type eye formationGO:004661930.010
response to nutrientGO:000758430.010
neural plate pattern specificationGO:0060896120.010
immunoglobulin mediated immune responseGO:001606430.010
erk1 and erk2 cascadeGO:007037140.010
regulation of protein localization to nucleusGO:190018020.010
cell cycle arrestGO:000705010.010
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.010
transmission of nerve impulseGO:0019226190.010
cellular lipid metabolic processGO:0044255360.010
cellular protein metabolic processGO:00442671290.010
negative regulation of immune responseGO:005077720.010

spon2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.097
bone diseaseDOID:008000100.043
musculoskeletal system diseaseDOID:1700.043
connective tissue diseaseDOID:6500.043
nervous system diseaseDOID:86300.021
inherited metabolic disorderDOID:65500.015
disease of metabolismDOID:001466700.015
eye diseaseDOID:561400.012
retinal diseaseDOID:567900.012
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012
muscular diseaseDOID:008000000.012
muscle tissue diseaseDOID:6600.012
immune system diseaseDOID:291400.011
hematopoietic system diseaseDOID:7400.011
anemiaDOID:235500.011
bone marrow diseaseDOID:496100.011
aplastic anemiaDOID:1244900.011