Danio rerio

90 known processes

mkks

McKusick-Kaufman syndrome

(Aliases: zgc:55608,MGC55608,bbs6)

mkks biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
single organism transportGO:00447652060.217
convergent extension involved in gastrulationGO:0060027710.204
regulation of metabolic processGO:00192223590.186
Mouse
response to stressGO:00069502630.160
digestive tract morphogenesisGO:00485462310.160
regulation of macromolecule metabolic processGO:00602553170.156
Mouse
negative regulation of biological processGO:00485193040.154
Mouse
sensory organ developmentGO:00074233930.143
regulation of primary metabolic processGO:00800903110.134
positive regulation of biological processGO:00485182530.133
Mouse
positive regulation of dna metabolic processGO:005105410.118
specification of symmetryGO:00097992040.117
cellular nitrogen compound metabolic processGO:00346412900.117
signal transductionGO:00071654550.104
Mouse
convergent extensionGO:00600261180.101
morphogenesis of an epitheliumGO:00020093330.098
negative regulation of cellular processGO:00485232830.095
gastrulationGO:00073692080.083
cellular macromolecule biosynthetic processGO:00346452240.082
nitrogen compound metabolic processGO:00068073190.079
alternative mrna splicing via spliceosomeGO:000038010.077
regulation of synapse assemblyGO:005196330.077
positive regulation of cellular component biogenesisGO:004408930.076
meiotic nuclear divisionGO:000712640.076
maternal determination of anterior posterior axis embryoGO:000835840.074
rna metabolic processGO:00160702190.074
spermatid differentiationGO:004851520.074
Mouse
digestive system developmentGO:00551232890.072
organic cyclic compound metabolic processGO:19013603010.072
cellular biosynthetic processGO:00442492860.072
regulation of synapse organizationGO:005080730.070
cell surface receptor signaling pathwayGO:00071663250.069
Mouse
homeostatic processGO:00425921420.068
Mouse
single organism localizationGO:19025782250.068
regionalizationGO:00030022740.068
cellular aromatic compound metabolic processGO:00067252950.068
positive regulation of metabolic processGO:00098931080.067
heart loopingGO:0001947940.067
neuron projection developmentGO:00311751800.066
single organism metabolic processGO:00447102170.066
nucleic acid metabolic processGO:00903042440.066
larval developmentGO:000216420.066
biosynthetic processGO:00090582940.063
positive regulation of cellular processGO:00485222010.063
digestive tract developmentGO:00485652650.063
cellular protein metabolic processGO:00442671290.062
response to chemicalGO:00422213200.061
Mouse
regulation of biosynthetic processGO:00098892500.061
regulation of circadian rhythmGO:004275240.059
tube morphogenesisGO:00352393490.058
oocyte anterior posterior axis specificationGO:000731440.058
intracellular mrna localizationGO:000829810.058
positive regulation of programmed cell deathGO:0043068290.058
aromatic compound biosynthetic processGO:00194382170.057
stem cell maintenanceGO:001982740.055
stem cell divisionGO:001714510.054
protein metabolic processGO:00195381830.054
regulation of signalingGO:00230512350.054
cellular process involved in reproduction in multicellular organismGO:0022412280.054
Mouse
nucleobase containing compound metabolic processGO:00061392740.053
g2 dna damage checkpointGO:003157230.052
nucleocytoplasmic transportGO:000691340.052
regulation of nitrogen compound metabolic processGO:00511712510.052
regulation of biological qualityGO:00650082630.051
Mouse
regulation of signal transductionGO:00099662250.050
cell motilityGO:00488702440.048
Mouse
regulation of protein complex assemblyGO:004325430.048
chemosensory behaviorGO:000763510.047
nuclear transportGO:005116940.046
regulation of gene expressionGO:00104682650.046
Mouse
eye developmentGO:00016542770.045
gene expressionGO:00104672520.044
Mouse
determination of bilateral symmetryGO:00098552040.044
negative regulation of nuclear divisionGO:005178430.044
regulation of cell communicationGO:00106462320.044
meiotic cell cycle processGO:190304630.043
regulation of macromolecule biosynthetic processGO:00105562250.043
heterocycle metabolic processGO:00464832900.043
head developmentGO:00603223030.043
Mouse
organic substance biosynthetic processGO:19015762890.043
cellular macromolecule metabolic processGO:00442603910.042
spermatid developmentGO:000728620.042
Mouse
ameboidal type cell migrationGO:00016671430.042
localization of cellGO:00516742440.041
Mouse
positive regulation of transportGO:005105020.041
small molecule metabolic processGO:0044281770.040
cytokinesisGO:000091030.040
regulation of cellular metabolic processGO:00313233200.040
regulation of cellular macromolecule biosynthetic processGO:20001122220.040
regulation of multicellular organismal processGO:00512392770.040
Mouse
neuron developmentGO:00486662620.040
organelle fissionGO:0048285230.039
positive regulation of cell cycleGO:004578730.039
regulation of response to stimulusGO:00485832690.039
Mouse
regulation of multicellular organismal developmentGO:20000262230.038
dna templated transcription initiationGO:000635210.038
heart developmentGO:00075073130.038
epithelial tube morphogenesisGO:00605621480.037
regulation of synaptic growth at neuromuscular junctionGO:000858210.037
intracellular signal transductionGO:0035556850.036
negative regulation of metabolic processGO:0009892860.036
Mouse
angiogenesisGO:00015251580.036
locomotionGO:00400113130.036
Mouse
cell migrationGO:00164772370.036
positive regulation of stress activated mapk cascadeGO:003287430.036
germ cell developmentGO:0007281220.035
Mouse
hematopoietic or lymphoid organ developmentGO:00485341910.035
vasculature developmentGO:00019442780.035
endosomal transportGO:001619720.035
activation of jun kinase activityGO:000725720.034
negative regulation of developmental processGO:0051093650.034
cell cycle g1 s phase transitionGO:004484310.034
actin polymerization or depolymerizationGO:000815420.034
pole plasm assemblyGO:000731540.033
female gonad developmentGO:000858540.033
cellular component biogenesisGO:00440851780.033
regulation of mrna splicing via spliceosomeGO:004802430.033
organelle organizationGO:00069962270.033
camera type eye developmentGO:00430102220.032
mitotic dna damage checkpointGO:004477340.032
cardiac atrium developmentGO:000323040.032
adult behaviorGO:003053420.032
ion transportGO:00068111140.031
mitotic cell cycleGO:0000278640.031
positive regulation of jun kinase activityGO:004350720.031
regulation of cellular biosynthetic processGO:00313262450.031
translational initiationGO:000641330.031
cellular component movementGO:00069283350.031
Mouse
regulation of alternative mrna splicing via spliceosomeGO:000038110.031
cell adhesionGO:0007155400.031
positive regulation of macromolecule metabolic processGO:0010604930.030
epithelial cell differentiationGO:00308551160.030
positive regulation of muscle cell differentiationGO:005114910.030
cellular component morphogenesisGO:00329893360.029
maintenance of locationGO:005123540.029
establishment of localizationGO:00512342440.029
positive regulation of cell deathGO:0010942290.029
single organism organelle organizationGO:19025891990.029
anterior posterior pattern specificationGO:00099521520.029
immune system developmentGO:00025201910.029
negative regulation of mitosisGO:004583930.028
nucleoside monophosphate catabolic processGO:000912540.028
regulation of cytokine productionGO:000181730.028
response to drugGO:004249330.028
regulation of cell shapeGO:000836010.027
regulation of growthGO:0040008420.027
Mouse
cognitionGO:005089010.027
positive regulation of cellular metabolic processGO:0031325940.027
positive regulation of translationGO:004572710.027
cell projection organizationGO:00300302840.027
cell deathGO:00082191210.027
gland developmentGO:00487321430.027
regulation of anatomical structure morphogenesisGO:00226031300.027
exocytosisGO:000688710.026
cell morphogenesis involved in differentiationGO:00009041950.025
regulation of tube sizeGO:003515020.025
Mouse
female sex differentiationGO:004666040.025
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.025
gene silencing by rnaGO:003104740.025
positive regulation of protein kinase b signalingGO:005189710.025
regulation of developmental processGO:00507932470.024
Mouse
programmed cell deathGO:00125011190.024
response to external stimulusGO:00096052640.024
Mouse
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.024
regulation of cytoplasmic transportGO:190364940.024
response to biotic stimulusGO:0009607970.024
periodic partitioningGO:000736510.024
organonitrogen compound metabolic processGO:1901564740.024
cell projection morphogenesisGO:00488582440.024
growthGO:00400071740.024
Mouse
cellular localizationGO:0051641970.023
nuclear divisionGO:0000280230.023
regulation of nucleic acid templated transcriptionGO:19035062130.023
mitotic cell cycle processGO:1903047480.023
neuron projection morphogenesisGO:00488121610.023
negative regulation of signal transductionGO:0009968940.023
regulation of cell differentiationGO:00455951420.023
mrna metabolic processGO:0016071200.023
phagocytosisGO:000690930.023
positive regulation of jnk cascadeGO:004633030.023
cytoskeleton organizationGO:0007010960.022
multi organism processGO:00517041340.022
Mouse
negative regulation of protein complex assemblyGO:003133310.022
rna splicingGO:0008380160.022
germ line stem cell divisionGO:004207810.022
axonogenesisGO:00074091520.022
regulation of stem cell differentiationGO:200073640.022
negative regulation of macromolecule metabolic processGO:0010605760.022
Mouse
immune system processGO:00023762410.022
purine ribonucleoside monophosphate catabolic processGO:000916940.022
rna localizationGO:000640340.022
deathGO:00162651210.022
macromolecular complex subunit organizationGO:0043933740.022
Mouse
cellular protein modification processGO:00064641000.021
positive regulation of apoptotic processGO:0043065290.021
single organism membrane fusionGO:004480120.021
ectodermal placode developmentGO:0071696370.021
female gamete generationGO:0007292140.021
negative regulation of multicellular organismal processGO:0051241690.021
negative regulation of cellular biosynthetic processGO:0031327550.020
embryonic organ morphogenesisGO:00485622740.020
developmental programmed cell deathGO:001062340.020
regulation of nucleobase containing compound metabolic processGO:00192192500.020
regulation of cell projection assemblyGO:006049140.020
regulation of multicellular organism growthGO:004001440.020
Mouse
synaptic growth at neuromuscular junctionGO:005112420.020
cellular response to external stimulusGO:007149620.020
atp catabolic processGO:000620040.020
inositol lipid mediated signalingGO:004801720.020
cell part morphogenesisGO:00329902460.020
response to organic substanceGO:00100331530.020
Mouse
gamete generationGO:0007276330.020
Mouse
regulation of jun kinase activityGO:004350630.020
positive regulation of canonical wnt signaling pathwayGO:009026340.020
regulation of apoptotic processGO:0042981980.020
multicellular organism growthGO:003526440.020
Mouse
cytoplasm organizationGO:000702840.019
meiosis iGO:000712710.019
nucleic acid templated transcriptionGO:00976591810.019
hemopoiesisGO:00300971830.019
positive regulation of protein complex assemblyGO:003133420.019
cellular nitrogen compound biosynthetic processGO:00442712180.019
chromosome organization involved in meiosisGO:007019210.019
regulation of rna metabolic processGO:00512522240.019
carboxylic acid metabolic processGO:0019752220.019
organic acid metabolic processGO:0006082310.019
regulation of wnt signaling pathwayGO:0030111530.019
negative regulation of gene expressionGO:0010629650.018
Mouse
axon developmentGO:00615641660.018
positive regulation of lipid metabolic processGO:004583410.018
positive regulation of cell killingGO:003134320.018
tissue remodelingGO:004877140.018
g1 s transition of mitotic cell cycleGO:000008210.018
regulation of establishment of protein localizationGO:007020140.018
oocyte maturationGO:000155640.018
oxoacid metabolic processGO:0043436310.018
organic cyclic compound biosynthetic processGO:19013622230.018
cell migration involved in heart developmentGO:0060973220.018
liver developmentGO:0001889960.018
generation of neuronsGO:00486993850.018
response to woundingGO:00096111160.018
positive regulation of cell adhesionGO:004578510.018
regulation of mrna catabolic processGO:006101330.018
embryonic pattern specificationGO:0009880440.018
cardiac atrium morphogenesisGO:000320920.018
developmental growth involved in morphogenesisGO:0060560860.018
liver morphogenesisGO:007257680.018
cell adhesion mediated by integrinGO:003362710.018
pigment granule localizationGO:0051875250.018
positive regulation of cellular biosynthetic processGO:0031328680.018
cell cycle arrestGO:000705010.017
brain developmentGO:00074202930.017
Mouse
regulation of transcription dna templatedGO:00063552130.017
protein polymerizationGO:005125840.017
positive regulation of cytokine productionGO:000181920.017
protein targeting to nucleusGO:004474430.017
cell morphogenesis involved in neuron differentiationGO:00486671630.017
macromolecule modificationGO:00434121110.017
negative regulation of catabolic processGO:000989530.017
nonmotile primary cilium assemblyGO:003505820.017
Mouse
purine nucleoside monophosphate catabolic processGO:000912840.017
protein localization to nucleusGO:003450430.017
regulation of cellular ketone metabolic processGO:001056570.017
one carbon compound transportGO:0019755140.016
phosphate containing compound metabolic processGO:00067961080.016
response to abiotic stimulusGO:00096281220.016
Mouse
regulation of establishment of planar polarityGO:009017540.016
heart morphogenesisGO:00030071560.016
transportGO:00068102200.016
response to hydrogen peroxideGO:004254230.016
neuroblast proliferationGO:000740520.016
negative regulation of response to stimulusGO:00485851040.016
Mouse
regulation of inflammatory responseGO:005072720.016
eye morphogenesisGO:00485921440.016
ubiquitin dependent protein catabolic processGO:000651130.016
macromolecule biosynthetic processGO:00090592270.016
hormone biosynthetic processGO:004244630.016
regulation of response to extracellular stimulusGO:003210410.016
Mouse
regulation of rna biosynthetic processGO:20011412130.016
negative regulation of synapse assemblyGO:005196420.016
positive regulation of cytoskeleton organizationGO:005149530.016
stem cell differentiationGO:00488631170.016
regulation of cell substrate adhesionGO:001081010.016
b cell differentiationGO:003018310.016
positive regulation of exocytosisGO:004592110.015
regulation of cellular component organizationGO:0051128860.015
dna catabolic processGO:000630810.015
peptidyl serine modificationGO:001820920.015
regulation of cell developmentGO:00602841000.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281200.015
cell cycleGO:0007049930.015
stem cell proliferationGO:007208940.015
kupffer s vesicle developmentGO:0070121500.015
neuron differentiationGO:00301823530.015
embryonic heart tube morphogenesisGO:00031431080.015
photoreceptor cell outer segment organizationGO:003584590.015
carbohydrate derivative metabolic processGO:1901135610.015
determination of left right symmetryGO:00073681790.015
regulation of cellular amine metabolic processGO:003323800.015
regulation of meiotic cell cycleGO:005144510.015
transcription dna templatedGO:00063511810.015
anatomical structure homeostasisGO:0060249360.015
Mouse
proteolysis involved in cellular protein catabolic processGO:005160330.015
organelle fusionGO:004828430.015
system processGO:00030081850.015
Mouse
cell morphogenesisGO:00009022890.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
cellular response to extracellular stimulusGO:003166820.014
spermatogenesisGO:000728370.014
Mouse
mitotic g2 dna damage checkpointGO:000709530.014
transcription from rna polymerase ii promoterGO:0006366800.014
entrainment of circadian clockGO:000964920.014
rna biosynthetic processGO:00327741810.014
recombinational repairGO:000072510.014
regulation of reactive oxygen species metabolic processGO:200037720.014
cellular ketone metabolic processGO:0042180110.014
negative regulation of epithelial cell proliferationGO:005068010.014
nucleobase containing compound biosynthetic processGO:00346542050.014
male meiosisGO:000714020.014
phosphatidylinositol mediated signalingGO:004801520.014
establishment of vesicle localizationGO:0051650240.014
cellular component assemblyGO:00226071700.014
regulation of nucleocytoplasmic transportGO:004682220.014
nuclear importGO:005117030.014
negative regulation of wnt signaling pathwayGO:0030178300.014
sex determinationGO:000753010.014
regulation of programmed cell deathGO:00430671010.014
protein modification processGO:00362111000.013
cytoskeleton dependent cytokinesisGO:006164030.013
regulation of mrna processingGO:005068430.013
response to carbohydrateGO:000974330.013
artery developmentGO:0060840220.013
wound healingGO:0042060900.013
cortical actin cytoskeleton organizationGO:003086610.013
negative regulation of protein phosphorylationGO:000193340.013
regulation of phGO:000688530.013
regulation of cell activationGO:005086510.013
regulation of cysteine type endopeptidase activityGO:2000116210.013
regulation of cell deathGO:00109411030.013
phagocytosis engulfmentGO:000691110.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
positive regulation of catabolic processGO:000989640.013
regulation of protein polymerizationGO:003227120.013
muscle cell migrationGO:001481240.013
modification dependent protein catabolic processGO:001994130.013
b cell activationGO:004211320.013
regulation of organelle organizationGO:0033043290.013
regulation of epithelial cell proliferationGO:005067830.013
gas transportGO:001566930.012
negative regulation of cellular metabolic processGO:0031324770.012
cellular response to biotic stimulusGO:007121630.012
positive regulation of neuron apoptotic processGO:004352510.012
chemical homeostasisGO:0048878490.012
tissue homeostasisGO:0001894250.012
Mouse
regulation of reproductive processGO:200024140.012
rna 3 end processingGO:003112320.012
positive regulation of erk1 and erk2 cascadeGO:007037420.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
negative regulation of dna metabolic processGO:005105340.012
negative chemotaxisGO:005091910.012
regulation of dna replicationGO:000627530.012
apoptotic processGO:00069151160.012
fin regenerationGO:0031101510.012
double strand break repair via homologous recombinationGO:000072410.012
erk1 and erk2 cascadeGO:007037140.012
neutrophil migrationGO:1990266100.012
ribonucleoside monophosphate catabolic processGO:000915840.012
regulation of canonical wnt signaling pathwayGO:0060828340.012
regulation of bindingGO:005109830.012
developmental growthGO:00485891660.012
Mouse
response to other organismGO:0051707970.012
neutrophil mediated immunityGO:000244610.012
c21 steroid hormone metabolic processGO:000820710.012
regulation of carbohydrate metabolic processGO:000610940.012
embryo development ending in birth or egg hatchingGO:00097922710.012
bone remodelingGO:004684920.012
compound eye developmentGO:004874920.011
cell migration to the midline involved in heart developmentGO:0003318120.011
cellular macromolecular complex assemblyGO:0034622240.011
Mouse
segment polarity determinationGO:000736710.011
regulation of metal ion transportGO:001095940.011
regulation of erk1 and erk2 cascadeGO:007037240.011
cellular response to radiationGO:007147840.011
ion transmembrane transportGO:0034220910.011
taxisGO:00423301090.011
tube closureGO:006060610.011
embryonic digestive tract developmentGO:004856640.011
fatty acid transportGO:001590810.011
cardioblast migration to the midline involved in heart field formationGO:006097570.011
microtubule organizing center organizationGO:003102310.011
cellular response to stressGO:0033554620.011
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.011
cell cycle processGO:0022402530.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.011
double strand break repairGO:000630230.011
regulation of organelle assemblyGO:190211540.011
pigment granule transportGO:0051904190.011
cellular response to decreased oxygen levelsGO:003629410.011
positive regulation of immune effector processGO:000269930.011
heterocycle biosynthetic processGO:00181302150.011
epithelial cell developmentGO:0002064420.011
regulation of glial cell differentiationGO:004568540.011
cell migration involved in heart formationGO:0060974100.011
negative regulation of mesodermal cell fate specificationGO:004266230.011
regulation of blood pressureGO:000821710.011
Mouse
regulation of cell motilityGO:2000145460.011
Mouse
regulation of cellular amino acid metabolic processGO:000652100.011
regulation of neuron differentiationGO:0045664560.011
negative regulation of multi organism processGO:004390130.011
regulation of protein metabolic processGO:0051246560.011
negative regulation of cellular catabolic processGO:003133030.011
regulation of exocytosisGO:001715710.011
positive regulation of cell divisionGO:005178120.011
cation transportGO:0006812810.010
multi organism reproductive processGO:0044703360.010
Mouse
specification of organ identityGO:001009220.010
development of primary female sexual characteristicsGO:004654540.010
synapsisGO:000712910.010
negative regulation of apoptotic processGO:0043066550.010
circulatory system processGO:0003013870.010
Mouse
lateral line system developmentGO:0048925760.010
sensory system developmentGO:0048880760.010
extrinsic apoptotic signaling pathwayGO:009719130.010
cellular pigmentationGO:0033059300.010
cell substrate junction assemblyGO:000704420.010
germ line stem cell maintenanceGO:003071820.010
somatic muscle developmentGO:000752540.010
transmembrane transportGO:00550851200.010
positive regulation of cellular catabolic processGO:003133130.010
embryonic organ developmentGO:00485683810.010
oogenesisGO:0048477140.010
proteasomal protein catabolic processGO:001049820.010
single fertilizationGO:000733830.010
vesicle localizationGO:0051648270.010
blood vessel morphogenesisGO:00485142160.010
regulation of protein transportGO:005122330.010
posttranscriptional regulation of gene expressionGO:0010608140.010
positive regulation of secretionGO:005104710.010

mkks disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.069
disease of metabolismDOID:001466700.027
inherited metabolic disorderDOID:65500.027
nervous system diseaseDOID:86300.027
brain diseaseDOID:93600.018
central nervous system diseaseDOID:33100.018
disease of cellular proliferationDOID:1456600.012
musculoskeletal system diseaseDOID:1700.012