Danio rerio

0 known processes

ldlr

low density lipoprotein receptor

ldlr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.077
response to chemicalGO:00422213200.059
regulation of biological qualityGO:00650082630.059
positive regulation of cellular catabolic processGO:003133130.057
regulation of metabolic processGO:00192223590.050
maintenance of locationGO:005123540.048
signal transductionGO:00071654550.047
regulation of primary metabolic processGO:00800903110.047
response to drugGO:004249330.047
positive regulation of catabolic processGO:000989640.046
positive regulation of transportGO:005105020.044
regulation of cellular macromolecule biosynthetic processGO:20001122220.044
regulation of nitrogen compound metabolic processGO:00511712510.044
cellular macromolecule metabolic processGO:00442603910.043
regulation of macromolecule metabolic processGO:00602553170.042
embryonic organ developmentGO:00485683810.041
nitrogen compound metabolic processGO:00068073190.040
agingGO:000756820.040
cellular amine metabolic processGO:004410620.040
adult behaviorGO:003053420.039
gene expressionGO:00104672520.039
cellular biosynthetic processGO:00442492860.038
cellular nitrogen compound metabolic processGO:00346412900.038
lipid storageGO:001991510.038
biosynthetic processGO:00090582940.037
regulation of signalingGO:00230512350.037
small molecule metabolic processGO:0044281770.036
transmembrane transportGO:00550851200.036
amine metabolic processGO:000930820.036
organic cyclic compound metabolic processGO:19013603010.036
regulation of multicellular organism growthGO:004001440.035
regulation of cellular amino acid metabolic processGO:000652100.035
regulation of protein catabolic processGO:004217610.035
regulation of cellular metabolic processGO:00313233200.035
cell surface receptor signaling pathwayGO:00071663250.034
aromatic compound biosynthetic processGO:00194382170.034
establishment of protein localization to organelleGO:007259440.034
regulation of gene expressionGO:00104682650.034
regulation of cellular amine metabolic processGO:003323800.034
organic substance biosynthetic processGO:19015762890.033
organic cyclic compound biosynthetic processGO:19013622230.033
tube morphogenesisGO:00352393490.033
cellular ketone metabolic processGO:0042180110.032
nucleic acid templated transcriptionGO:00976591810.032
rna biosynthetic processGO:00327741810.032
response to vitaminGO:003327330.032
response to external stimulusGO:00096052640.032
cellular response to nutrient levelsGO:003166920.032
central nervous system developmentGO:00074173870.032
regulation of cell communicationGO:00106462320.032
cation transmembrane transportGO:0098655650.032
transcription from rna polymerase ii promoterGO:0006366800.032
regulation of cellular ketone metabolic processGO:001056570.031
ion transmembrane transportGO:0034220910.031
establishment of localizationGO:00512342440.031
cellular response to external stimulusGO:007149620.031
heterocycle metabolic processGO:00464832900.030
cellular macromolecule biosynthetic processGO:00346452240.030
regulation of protein complex assemblyGO:004325430.030
response to nutrientGO:000758430.029
regulation of signal transductionGO:00099662250.029
regulation of cytokine productionGO:000181730.029
heterocycle biosynthetic processGO:00181302150.029
cellular aromatic compound metabolic processGO:00067252950.029
regulation of transcription from rna polymerase ii promoterGO:00063571140.029
single organism metabolic processGO:00447102170.029
multicellular organism growthGO:003526440.029
regulation of tube sizeGO:003515020.028
organonitrogen compound metabolic processGO:1901564740.028
response to stressGO:00069502630.028
regulation of nucleobase containing compound metabolic processGO:00192192500.028
regulation of biosynthetic processGO:00098892500.028
digestive system developmentGO:00551232890.028
transcription dna templatedGO:00063511810.027
regulation of rna metabolic processGO:00512522240.027
regulation of macromolecule biosynthetic processGO:00105562250.027
cellular component movementGO:00069283350.027
regulation of response to stimulusGO:00485832690.027
negative regulation of cellular processGO:00485232830.027
protein importGO:001703830.027
nucleobase containing compound metabolic processGO:00061392740.027
response to organic substanceGO:00100331530.026
cellular amino acid metabolic processGO:000652070.026
phagocytosisGO:000690930.026
determination of bilateral symmetryGO:00098552040.026
rna metabolic processGO:00160702190.026
organic acid metabolic processGO:0006082310.026
embryonic organ morphogenesisGO:00485622740.026
regionalizationGO:00030022740.026
gtp metabolic processGO:004603940.025
single organism transportGO:00447652060.025
cellular carbohydrate metabolic processGO:004426240.025
carbohydrate biosynthetic processGO:001605110.025
cellular nitrogen compound biosynthetic processGO:00442712180.025
regulation of rna biosynthetic processGO:20011412130.025
regulation of transcription dna templatedGO:00063552130.025
positive regulation of cytokine productionGO:000181920.025
negative regulation of protein phosphorylationGO:000193340.025
macromolecule biosynthetic processGO:00090592270.024
regulation of synaptic plasticityGO:004816710.024
regulation of inflammatory responseGO:005072720.024
cellular response to extracellular stimulusGO:003166820.024
nucleobase containing compound biosynthetic processGO:00346542050.024
positive regulation of cellular component biogenesisGO:004408930.024
positive regulation of cell cycleGO:004578730.024
transportGO:00068102200.024
regulation of cellular biosynthetic processGO:00313262450.023
vasculature developmentGO:00019442780.023
regulation of blood vessel sizeGO:005088020.023
guanosine containing compound metabolic processGO:190106840.023
oxoacid metabolic processGO:0043436310.023
cellular response to starvationGO:000926710.023
autophagyGO:000691440.023
regulation of bindingGO:005109830.023
phosphatidylinositol 3 kinase signalingGO:001406520.023
specification of symmetryGO:00097992040.023
regulation of muscle contractionGO:000693730.023
brain developmentGO:00074202930.022
gtp catabolic processGO:000618420.022
nuclear transportGO:005116940.022
cognitionGO:005089010.022
regulation of reactive oxygen species metabolic processGO:200037720.022
positive regulation of blood circulationGO:190352420.022
regulation of peptidyl tyrosine phosphorylationGO:005073010.022
synaptic transmission cholinergicGO:000727140.022
regulation of phGO:000688530.021
regulation of nucleoside metabolic processGO:000911820.021
regulation of nucleotide catabolic processGO:003081120.021
regulation of transmembrane transporter activityGO:002289820.021
regulation of developmental processGO:00507932470.021
negative regulation of biological processGO:00485193040.021
muscle structure developmentGO:00610611960.021
single organism localizationGO:19025782250.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
fatty acid transportGO:001590810.021
regulation of multicellular organismal processGO:00512392770.021
regulation of carbohydrate metabolic processGO:000610940.021
stem cell proliferationGO:007208940.021
carboxylic acid metabolic processGO:0019752220.021
regulation of ion transmembrane transporter activityGO:003241220.021
guanosine containing compound catabolic processGO:190106920.020
response to carbohydrateGO:000974330.020
nucleic acid metabolic processGO:00903042440.020
tissue remodelingGO:004877140.020
cellular response to chemical stimulusGO:00708871570.020
regulation of nucleic acid templated transcriptionGO:19035062130.020
positive regulation of biological processGO:00485182530.020
dorsal ventral pattern formationGO:00099531250.020
synaptic growth at neuromuscular junctionGO:005112420.020
generation of neuronsGO:00486993850.020
hormone secretionGO:004687920.020
g1 s transition of mitotic cell cycleGO:000008210.020
cell motilityGO:00488702440.019
protein targeting to nucleusGO:004474430.019
protein localization to nucleusGO:003450430.019
negative regulation of protein kinase activityGO:000646940.019
regulation of wound healingGO:006104120.019
cellular component morphogenesisGO:00329893360.019
protein localization to plasma membraneGO:007265910.019
regulation of cellular carbohydrate metabolic processGO:001067540.019
inositol lipid mediated signalingGO:004801720.018
cell projection morphogenesisGO:00488582440.018
positive regulation of cellular amine metabolic processGO:003324000.018
regulation of cell activationGO:005086510.018
protein secretionGO:000930610.018
negative regulation of catabolic processGO:000989530.018
regulation of purine nucleotide catabolic processGO:003312120.018
positive regulation of cellular processGO:00485222010.018
negative regulation of kinase activityGO:003367340.018
digestive tract developmentGO:00485652650.018
locomotionGO:00400113130.018
cellular response to xenobiotic stimulusGO:0071466350.018
regulation of gtp catabolic processGO:003312420.018
stem cell maintenanceGO:001982740.018
regulation of striated muscle contractionGO:000694220.018
proteolysis involved in cellular protein catabolic processGO:005160330.018
positive regulation of secretionGO:005104710.017
regulation of protein transportGO:005122330.017
smooth muscle contractionGO:000693920.017
small molecule catabolic processGO:004428230.017
enzyme linked receptor protein signaling pathwayGO:00071671060.017
cellular component biogenesisGO:00440851780.017
localization of cellGO:00516742440.017
cell cycle g1 s phase transitionGO:004484310.017
muscle cell developmentGO:00550011150.017
neuron differentiationGO:00301823530.017
protein import into nucleusGO:000660630.017
regulation of metal ion transportGO:001095940.017
sodium ion transmembrane transportGO:0035725210.017
blood vessel developmentGO:00015682460.017
response to corticosteroidGO:003196010.017
system processGO:00030081850.017
organelle organizationGO:00069962270.017
heart loopingGO:0001947940.017
membrane fusionGO:006102520.016
nucleocytoplasmic transportGO:000691340.016
digestive tract morphogenesisGO:00485462310.016
protein metabolic processGO:00195381830.016
regulation of anatomical structure morphogenesisGO:00226031300.016
regulation of intracellular protein transportGO:003315730.016
multicellular organismal metabolic processGO:004423620.016
single organism organelle organizationGO:19025891990.016
nuclear importGO:005117030.016
extrinsic apoptotic signaling pathwayGO:009719130.016
positive regulation of nucleotide catabolic processGO:003081310.016
single organism nuclear importGO:190259330.016
regulation of establishment of protein localizationGO:007020140.016
regulation of cytoplasmic transportGO:190364940.016
cellular response to organic substanceGO:00713101050.016
head developmentGO:00603223030.016
response to endogenous stimulusGO:0009719830.016
protein polymerizationGO:005125840.016
cell migrationGO:00164772370.015
homeostatic processGO:00425921420.015
determination of left right symmetryGO:00073681790.015
regulation of reproductive processGO:200024140.015
mitochondrion organizationGO:000700540.015
inorganic ion transmembrane transportGO:0098660570.015
regulation of gtpase activityGO:004308720.015
negative regulation of mapk cascadeGO:004340940.015
morphogenesis of an epitheliumGO:00020093330.015
regulation of multicellular organismal developmentGO:20000262230.015
programmed cell deathGO:00125011190.015
inorganic cation transmembrane transportGO:0098662500.015
germ line stem cell divisionGO:004207810.015
developmental programmed cell deathGO:001062340.015
immune system processGO:00023762410.015
monovalent inorganic cation transportGO:0015672420.015
response to xenobiotic stimulusGO:0009410450.015
wound healingGO:0042060900.015
regulation of cellular protein catabolic processGO:190336210.015
positive regulation of gtp catabolic processGO:003312610.015
negative regulation of cytokine productionGO:000181810.015
circulatory system processGO:0003013870.015
cellular component assemblyGO:00226071700.015
complement activationGO:000695630.015
female sex differentiationGO:004666040.014
hormone transportGO:000991420.014
establishment of protein localization to plasma membraneGO:009000210.014
sensory organ morphogenesisGO:00905962000.014
atp catabolic processGO:000620040.014
positive regulation of gtpase activityGO:004354710.014
blood vessel morphogenesisGO:00485142160.014
embryo development ending in birth or egg hatchingGO:00097922710.014
post embryonic organ developmentGO:004856940.014
gastrulationGO:00073692080.014
cellular protein catabolic processGO:004425740.014
response to alkaloidGO:004327920.014
development of primary female sexual characteristicsGO:004654540.014
modification dependent macromolecule catabolic processGO:004363230.014
actin filament based movementGO:003004810.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
blood circulationGO:0008015870.014
regulation of transporter activityGO:003240920.014
protein dephosphorylationGO:000647030.014
stem cell divisionGO:001714510.014
b cell activationGO:004211320.014
negative regulation of cellular metabolic processGO:0031324770.014
negative regulation of signal transductionGO:0009968940.014
growthGO:00400071740.014
positive regulation of stress activated mapk cascadeGO:003287430.014
peptide transportGO:001583310.014
long chain fatty acid metabolic processGO:000167610.013
gland developmentGO:00487321430.013
cartilage developmentGO:0051216960.013
female gonad developmentGO:000858540.013
negative regulation of defense responseGO:003134820.013
neuron neuron synaptic transmissionGO:000727010.013
intracellular signal transductionGO:0035556850.013
inorganic anion transportGO:0015698250.013
camera type eye developmentGO:00430102220.013
cellular component disassemblyGO:002241110.013
g protein coupled receptor signaling pathwayGO:0007186740.013
response to glucocorticoidGO:005138410.013
bmp signaling pathwayGO:0030509520.013
negative regulation of cellular catabolic processGO:003133030.013
organelle fusionGO:004828430.013
regulation of dendrite developmentGO:005077330.013
modification dependent protein catabolic processGO:001994130.013
skeletal system morphogenesisGO:00487051020.013
actin mediated cell contractionGO:007025210.013
response to oxygen containing compoundGO:1901700550.013
response to uvGO:000941130.013
eye developmentGO:00016542770.013
lipid oxidationGO:003444010.013
regulation of neurotransmitter transportGO:005158810.013
connective tissue developmentGO:0061448990.013
response to woundingGO:00096111160.013
developmental growthGO:00485891660.013
protein stabilizationGO:005082120.013
response to hydrogen peroxideGO:004254230.013
regulation of erk1 and erk2 cascadeGO:007037240.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.013
response to transition metal nanoparticleGO:1990267280.013
chordate embryonic developmentGO:00430092710.013
carbohydrate homeostasisGO:003350010.013
ion transportGO:00068111140.013
single organism membrane fusionGO:004480120.013
response to amino acidGO:004320020.013
negative regulation of metabolic processGO:0009892860.013
response to external biotic stimulusGO:0043207970.013
organelle assemblyGO:00709251100.013
regulation of organ growthGO:004662030.013
response to monosaccharideGO:003428430.013
response to topologically incorrect proteinGO:003596620.013
regulation of localizationGO:00328791040.013
sleepGO:003043110.013
positive regulation of map kinase activityGO:004340630.013
embryonic heart tube morphogenesisGO:00031431080.012
regulation of protein import into nucleusGO:004230620.012
striated muscle cell differentiationGO:00511461290.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
cell cell recognitionGO:000998810.012
positive regulation of secretion by cellGO:190353210.012
negative regulation of macromolecule metabolic processGO:0010605760.012
regulation of cell differentiationGO:00455951420.012
cell part morphogenesisGO:00329902460.012
regulation of apoptotic processGO:0042981980.012
gas transportGO:001566930.012
cellular response to oxygen levelsGO:007145310.012
cellular component assembly involved in morphogenesisGO:00109271070.012
regulation of sodium ion transportGO:000202820.012
response to hexoseGO:000974630.012
regulation of jak stat cascadeGO:004642530.012
mesenchyme developmentGO:00604851270.012
striated muscle cell developmentGO:00550021080.012
cellular response to radiationGO:007147840.012
regulation of cell shapeGO:000836010.012
angiogenesisGO:00015251580.012
cation transportGO:0006812810.012
trabecula morphogenesisGO:006138320.012
positive regulation of nucleoside metabolic processGO:004597910.012
regulation of cell deathGO:00109411030.012
positive regulation of cell adhesionGO:004578510.012
cell morphogenesisGO:00009022890.012
cellular lipid catabolic processGO:004424230.012
negative regulation of cell communicationGO:0010648960.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
apoptotic processGO:00069151160.012
regulation of membrane potentialGO:0042391230.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
regulation of protein targetingGO:190353320.012
multi organism processGO:00517041340.011
muscle cell differentiationGO:00426921390.011
mononuclear cell proliferationGO:003294310.011
negative regulation of signalingGO:0023057960.011
endocrine processGO:005088620.011
regulation of cell substrate adhesionGO:001081010.011
carbon dioxide transportGO:001567030.011
heart developmentGO:00075073130.011
regulation of autophagyGO:001050630.011
regulation of circadian rhythmGO:004275240.011
sensory perception of chemical stimulusGO:000760630.011
cellular amide metabolic processGO:004360340.011
regulation of nucleocytoplasmic transportGO:004682220.011
response to glucoseGO:000974930.011
cell projection organizationGO:00300302840.011
microtubule polymerization or depolymerizationGO:003110930.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
regulation of epithelial cell proliferationGO:005067830.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
mesenchymal cell differentiationGO:0048762870.011
cell substrate adhesionGO:003158940.011
epithelial tube morphogenesisGO:00605621480.011
leukocyte proliferationGO:007066110.011
negative regulation of response to stimulusGO:00485851040.011
regulation of cellular component movementGO:0051270550.011
positive regulation of heart contractionGO:004582320.011
notochord developmentGO:0030903540.011
reactive oxygen species biosynthetic processGO:190340910.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
peptide metabolic processGO:000651810.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
alcohol biosynthetic processGO:004616520.011
astrocyte differentiationGO:004870810.011
positive regulation of cytoskeleton organizationGO:005149530.011
phosphatidylinositol mediated signalingGO:004801520.011
phosphate containing compound metabolic processGO:00067961080.011
protein homooligomerizationGO:005126030.011
regulation of programmed cell deathGO:00430671010.011
nuclear migrationGO:000709730.011
proteasomal protein catabolic processGO:001049820.011
embryonic skeletal system morphogenesisGO:0048704930.011
cellular protein metabolic processGO:00442671290.011
cellular response to reactive oxygen speciesGO:003461420.011
action potentialGO:0001508190.011
internal protein amino acid acetylationGO:000647520.011
cellular response to lipopolysaccharideGO:007122230.011
embryonic skeletal system developmentGO:0048706970.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.011
regulation of blood pressureGO:000821710.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
positive regulation of protein complex assemblyGO:003133420.010
water transportGO:0006833150.010
sensory organ developmentGO:00074233930.010
regulation of stem cell differentiationGO:200073640.010
g2 m transition of mitotic cell cycleGO:000008640.010
mitotic dna damage checkpointGO:004477340.010
axon ensheathment in central nervous systemGO:003229120.010
protein complex disassemblyGO:004324110.010
macromolecular complex disassemblyGO:003298410.010
regulation of glucose transportGO:001082710.010
regulation of system processGO:0044057400.010
cell morphogenesis involved in differentiationGO:00009041950.010
peptidyl lysine acetylationGO:001839420.010
deathGO:00162651210.010
lipid homeostasisGO:005508830.010
cellular aldehyde metabolic processGO:000608140.010

ldlr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
nervous system diseaseDOID:86300.017
cancerDOID:16200.016
organ system cancerDOID:005068600.016
disease of cellular proliferationDOID:1456600.016
musculoskeletal system diseaseDOID:1700.015
sensory system diseaseDOID:005015500.012
eye diseaseDOID:561400.012
eye and adnexa diseaseDOID:149200.012
disease of metabolismDOID:001466700.011
muscular diseaseDOID:008000000.011
muscle tissue diseaseDOID:6600.011
myopathyDOID:42300.010
cardiovascular system diseaseDOID:128700.010