Danio rerio

17 known processes

ptprja

protein tyrosine phosphatase, receptor type, J a

(Aliases: fb08b12,dep1a,wu:fb08b12)

ptprja biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
blood vessel developmentGO:00015682460.405
artery developmentGO:0060840220.351
ventricular cardiac muscle tissue morphogenesisGO:005501020.222
artery morphogenesisGO:0048844140.191
cellular component morphogenesisGO:00329893360.177
regulation of cell communicationGO:00106462320.159
somite developmentGO:0061053960.119
hemopoiesisGO:00300971830.117
cell surface receptor signaling pathwayGO:00071663250.110
positive regulation of biological processGO:00485182530.107
embryonic organ developmentGO:00485683810.097
regulation of signal transductionGO:00099662250.095
vasculature developmentGO:00019442780.093
signal transductionGO:00071654550.091
positive regulation of cellular processGO:00485222010.086
mesenchymal cell differentiationGO:0048762870.083
immune system developmentGO:00025201910.082
cognitionGO:005089010.079
rna biosynthetic processGO:00327741810.077
vascular endothelial growth factor receptor signaling pathwayGO:0048010130.076
tube morphogenesisGO:00352393490.076
cell morphogenesisGO:00009022890.076
angiogenesisGO:00015251580.075
larval developmentGO:000216420.075
myeloid cell differentiationGO:0030099860.074
generation of neuronsGO:00486993850.073
eye developmentGO:00016542770.073
proteasomal protein catabolic processGO:001049820.072
regulation of metabolic processGO:00192223590.071
regulation of transcription from rna polymerase ii promoterGO:00063571140.070
regulation of cell substrate adhesionGO:001081010.069
cilium morphogenesisGO:0060271850.067
regulation of synaptic plasticityGO:004816710.067
response to biotic stimulusGO:0009607970.065
development of primary female sexual characteristicsGO:004654540.064
positive regulation of epithelial cell proliferationGO:005067910.064
heterocycle metabolic processGO:00464832900.062
modification dependent macromolecule catabolic processGO:004363230.062
ventricular cardiac muscle tissue developmentGO:000322930.062
nucleic acid templated transcriptionGO:00976591810.061
organic cyclic compound biosynthetic processGO:19013622230.061
regulation of nucleic acid templated transcriptionGO:19035062130.060
blood vessel morphogenesisGO:00485142160.060
nucleobase containing compound biosynthetic processGO:00346542050.059
regulation of canonical wnt signaling pathwayGO:0060828340.058
regulation of gene expressionGO:00104682650.057
biosynthetic processGO:00090582940.057
cell substrate adhesionGO:003158940.057
aromatic compound biosynthetic processGO:00194382170.053
regionalizationGO:00030022740.052
response to stressGO:00069502630.052
trabecula morphogenesisGO:006138320.052
cellular nitrogen compound biosynthetic processGO:00442712180.051
protein complex subunit organizationGO:0071822460.051
female sex differentiationGO:004666040.051
negative regulation of protein kinase activityGO:000646940.051
regulation of signalingGO:00230512350.051
ubiquitin dependent protein catabolic processGO:000651130.050
hematopoietic or lymphoid organ developmentGO:00485341910.050
chordate embryonic developmentGO:00430092710.050
regulation of developmental processGO:00507932470.050
urogenital system developmentGO:0001655970.050
chemosensory behaviorGO:000763510.050
regulation of protein catabolic processGO:004217610.049
bmp signaling pathwayGO:0030509520.048
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.048
organic cyclic compound metabolic processGO:19013603010.047
proteolysis involved in cellular protein catabolic processGO:005160330.047
positive regulation of canonical wnt signaling pathwayGO:009026340.046
regulation of nucleocytoplasmic transportGO:004682220.045
regulation of cell matrix adhesionGO:000195210.045
positive regulation of cell substrate adhesionGO:001081110.045
cellular macromolecule metabolic processGO:00442603910.044
regulation of wnt signaling pathwayGO:0030111530.044
cell motilityGO:00488702440.042
negative regulation of signalingGO:0023057960.042
cellular protein catabolic processGO:004425740.042
positive regulation of transportGO:005105020.042
female gonad developmentGO:000858540.041
regulation of biosynthetic processGO:00098892500.041
mesenchyme developmentGO:00604851270.040
regulation of cell shapeGO:000836010.040
renal system developmentGO:0072001940.040
sensory perception of chemical stimulusGO:000760630.040
neurotransmitter secretionGO:000726920.039
nitrogen compound metabolic processGO:00068073190.039
positive regulation of cell cycleGO:004578730.039
regulation of macromolecule metabolic processGO:00602553170.038
regulation of epithelial cell proliferationGO:005067830.038
positive regulation of cellular metabolic processGO:0031325940.038
modification dependent protein catabolic processGO:001994130.038
negative regulation of cell communicationGO:0010648960.038
cellular biosynthetic processGO:00442492860.038
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.038
heart developmentGO:00075073130.037
morphogenesis of an epitheliumGO:00020093330.037
behaviorGO:0007610740.037
regulation of multicellular organismal developmentGO:20000262230.037
heterocycle biosynthetic processGO:00181302150.037
regulation of endothelial cell proliferationGO:000193610.036
regulation of intracellular protein transportGO:003315730.036
cell part morphogenesisGO:00329902460.036
negative regulation of metabolic processGO:0009892860.036
heart morphogenesisGO:00030071560.036
system processGO:00030081850.036
regulation of cell differentiationGO:00455951420.036
negative regulation of cellular processGO:00485232830.036
embryonic heart tube developmentGO:00350501330.035
agingGO:000756820.035
regulation of protein targetingGO:190353320.035
regulation of nitrogen compound metabolic processGO:00511712510.035
phagocytosisGO:000690930.035
regulation of transcription dna templatedGO:00063552130.034
antimicrobial humoral responseGO:001973020.034
cellular component assembly involved in morphogenesisGO:00109271070.034
ameboidal type cell migrationGO:00016671430.034
negative regulation of kinase activityGO:003367340.033
synaptic growth at neuromuscular junctionGO:005112420.033
negative regulation of multicellular organismal processGO:0051241690.033
multi organism processGO:00517041340.033
mesenchymal cell developmentGO:0014031780.033
embryo development ending in birth or egg hatchingGO:00097922710.033
rna metabolic processGO:00160702190.033
gene expressionGO:00104672520.033
positive regulation of cellular catabolic processGO:003133130.033
protein import into nucleusGO:000660630.032
regulation of protein transportGO:005122330.032
eye morphogenesisGO:00485921440.032
regulation of rna metabolic processGO:00512522240.032
regulation of response to stimulusGO:00485832690.031
regulation of multicellular organismal processGO:00512392770.031
maintenance of locationGO:005123540.031
camera type eye developmentGO:00430102220.031
transcription dna templatedGO:00063511810.031
sensory organ developmentGO:00074233930.031
determination of left right symmetryGO:00073681790.031
neuron differentiationGO:00301823530.031
establishment of protein localization to organelleGO:007259440.030
multicellular organismal reproductive processGO:0048609350.030
lipid storageGO:001991510.030
protein importGO:001703830.029
synaptic vesicle transportGO:004848910.029
negative regulation of map kinase activityGO:004340720.029
regulation of rna biosynthetic processGO:20011412130.029
regulation of establishment of protein localizationGO:007020140.029
regulation of tube sizeGO:003515020.029
neurotransmitter transportGO:000683620.029
embryonic organ morphogenesisGO:00485622740.028
regulation of cellular metabolic processGO:00313233200.028
actin polymerization or depolymerizationGO:000815420.028
positive regulation of cell adhesionGO:004578510.028
cellular nitrogen compound metabolic processGO:00346412900.028
cell projection assemblyGO:0030031640.028
somitogenesisGO:0001756870.028
regulation of biological qualityGO:00650082630.028
response to chemicalGO:00422213200.028
nucleobase containing compound metabolic processGO:00061392740.028
multicellular organism growthGO:003526440.028
cell matrix adhesionGO:000716040.027
regulation of protein localization to nucleusGO:190018020.027
tissue remodelingGO:004877140.027
i kappab kinase nf kappab signalingGO:000724940.027
synaptic vesicle localizationGO:009747910.027
regulation of primary metabolic processGO:00800903110.027
cellular component assemblyGO:00226071700.027
nucleic acid metabolic processGO:00903042440.027
neuron developmentGO:00486662620.027
regulation of reproductive processGO:200024140.027
protein localization to nucleusGO:003450430.026
regulation of cellular biosynthetic processGO:00313262450.026
positive regulation of endothelial cell proliferationGO:000193810.026
stem cell developmentGO:0048864820.026
regulation of bmp signaling pathwayGO:0030510390.026
muscle organ morphogenesisGO:004864480.026
regulation of neurotransmitter transportGO:005158810.026
organic substance biosynthetic processGO:19015762890.026
stem cell proliferationGO:007208940.026
negative regulation of mapk cascadeGO:004340940.026
cartilage developmentGO:0051216960.026
cell projection morphogenesisGO:00488582440.026
protein secretionGO:000930610.026
meiotic nuclear divisionGO:000712640.025
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.025
single organism nuclear importGO:190259330.025
positive regulation of muscle cell differentiationGO:005114910.025
cell cycleGO:0007049930.025
response to external biotic stimulusGO:0043207970.025
transportGO:00068102200.025
negative regulation of biological processGO:00485193040.025
sensory organ morphogenesisGO:00905962000.025
regulation of neural precursor cell proliferationGO:200017730.025
cellular response to external stimulusGO:007149620.025
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.025
regulation of organ growthGO:004662030.024
regulation of sequestering of calcium ionGO:005128240.024
macromolecule biosynthetic processGO:00090592270.024
regulation of bindingGO:005109830.024
cell projection organizationGO:00300302840.024
regulation of cellular macromolecule biosynthetic processGO:20001122220.024
cellular macromolecule biosynthetic processGO:00346452240.024
negative regulation of protein phosphorylationGO:000193340.024
positive regulation of erk1 and erk2 cascadeGO:007037420.024
adherens junction organizationGO:003433240.024
establishment of localizationGO:00512342440.024
cellular aromatic compound metabolic processGO:00067252950.024
nucleocytoplasmic transportGO:000691340.024
negative regulation of secretion by cellGO:190353120.024
nuclear importGO:005117030.023
localization of cellGO:00516742440.023
protein targeting to nucleusGO:004474430.023
osteoclast differentiationGO:003031610.023
endocrine system developmentGO:0035270650.023
positive regulation of catabolic processGO:000989640.023
ear developmentGO:00435831270.023
erk1 and erk2 cascadeGO:007037140.023
mitochondrion organizationGO:000700540.023
inositol lipid mediated signalingGO:004801720.023
aminoglycan metabolic processGO:000602290.023
lymph vessel developmentGO:0001945270.022
negative regulation of gene expressionGO:0010629650.022
single organism metabolic processGO:00447102170.022
negative regulation of rna metabolic processGO:0051253480.022
single organism organelle organizationGO:19025891990.022
regulation of mesenchymal cell proliferationGO:001046410.022
transcription from rna polymerase ii promoterGO:0006366800.022
regulation of macromolecule biosynthetic processGO:00105562250.022
positive regulation of metabolic processGO:00098931080.022
response to growth factorGO:0070848390.022
stem cell differentiationGO:00488631170.022
cell cycle g1 s phase transitionGO:004484310.022
neuron neuron synaptic transmissionGO:000727010.022
regulation of cell deathGO:00109411030.022
response to nutrientGO:000758430.022
aorta developmentGO:003590440.021
positive regulation of cellular component biogenesisGO:004408930.021
apoptotic processGO:00069151160.021
regulation of erk1 and erk2 cascadeGO:007037240.021
positive regulation of response to stimulusGO:0048584800.021
positive regulation of nitrogen compound metabolic processGO:0051173690.021
apoptotic process involved in developmentGO:190274220.021
immune system processGO:00023762410.021
cilium organizationGO:0044782710.021
connective tissue developmentGO:0061448990.021
regulation of cytokine productionGO:000181730.021
regulation of nucleobase containing compound metabolic processGO:00192192500.021
mitotic cell cycle processGO:1903047480.021
regulation of autophagyGO:001050630.021
cellular component biogenesisGO:00440851780.021
rna localizationGO:000640340.021
epithelial cell differentiationGO:00308551160.021
head developmentGO:00603223030.021
neuron projection morphogenesisGO:00488121610.021
regulation of muscle contractionGO:000693730.021
glycosaminoglycan metabolic processGO:003020390.021
negative regulation of macromolecule biosynthetic processGO:0010558480.020
phagocytosis engulfmentGO:000691110.020
convergent extensionGO:00600261180.020
meiotic cell cycle processGO:190304630.020
response to external stimulusGO:00096052640.020
gtp catabolic processGO:000618420.020
regulation of anatomical structure morphogenesisGO:00226031300.020
cellular response to extracellular stimulusGO:003166820.020
b cell differentiationGO:003018310.020
enzyme linked receptor protein signaling pathwayGO:00071671060.020
mesoderm developmentGO:0007498880.020
cellular response to starvationGO:000926710.020
positive regulation of macromolecule biosynthetic processGO:0010557590.020
positive regulation of cytokine productionGO:000181920.020
regulation of programmed cell deathGO:00430671010.019
negative regulation of synapse assemblyGO:005196420.019
regulation of neurotransmitter secretionGO:004692810.019
positive regulation of macromolecule metabolic processGO:0010604930.019
protein metabolic processGO:00195381830.019
regulation of cellular protein catabolic processGO:190336210.019
negative regulation of protein serine threonine kinase activityGO:007190120.019
regulation of cellular amine metabolic processGO:003323800.019
smooth muscle contractionGO:000693920.019
cellular response to nutrient levelsGO:003166920.019
establishment of synaptic vesicle localizationGO:009748010.019
wnt signaling pathwayGO:0016055800.019
regulation of nervous system developmentGO:0051960900.019
regulation of meiotic cell cycleGO:005144510.019
brain developmentGO:00074202930.019
pigment cell differentiationGO:0050931380.019
regulation of cytoplasmic transportGO:190364940.019
single organism localizationGO:19025782250.018
segmentationGO:0035282970.018
liver developmentGO:0001889960.018
organic acid metabolic processGO:0006082310.018
positive regulation of cytoskeleton organizationGO:005149530.018
protein localization to plasma membraneGO:007265910.018
regulation of blood circulationGO:1903522320.018
regulation of cell activationGO:005086510.018
regulation of stem cell differentiationGO:200073640.018
specification of axis polarityGO:006500140.018
regulation of cellular response to growth factor stimulusGO:0090287350.018
sequestering of calcium ionGO:005120830.018
organelle organizationGO:00069962270.018
response to monosaccharideGO:003428430.018
muscle tissue developmentGO:00605371100.018
multi organism reproductive processGO:0044703360.018
b cell activationGO:004211320.018
negative regulation of signal transductionGO:0009968940.017
gtp metabolic processGO:004603940.017
growthGO:00400071740.017
positive regulation of rna biosynthetic processGO:1902680570.017
developmental pigmentationGO:0048066480.017
regulation of apoptotic processGO:0042981980.017
positive regulation of map kinase activityGO:004340630.017
positive regulation of cell divisionGO:005178120.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.017
regulation of synapse organizationGO:005080730.017
mitotic cell cycleGO:0000278640.017
neurological system processGO:0050877620.017
specification of symmetryGO:00097992040.017
regulation of multicellular organism growthGO:004001440.017
meiotic chromosome segregationGO:004513230.017
regulation of circadian rhythmGO:004275240.017
aorta morphogenesisGO:003590930.017
canonical wnt signaling pathwayGO:0060070480.017
regulation of cellular amino acid metabolic processGO:000652100.017
negative regulation of nitrogen compound metabolic processGO:0051172590.017
locomotionGO:00400113130.017
determination of bilateral symmetryGO:00098552040.017
negative regulation of nucleic acid templated transcriptionGO:1903507450.017
chemical homeostasisGO:0048878490.017
organelle assemblyGO:00709251100.016
intracellular signal transductionGO:0035556850.016
negative regulation of nucleocytoplasmic transportGO:004682320.016
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
regulation of blood vessel sizeGO:005088020.016
positive regulation of signal transductionGO:0009967560.016
regulation of intracellular signal transductionGO:1902531570.016
lateral line developmentGO:0048882660.016
digestive system developmentGO:00551232890.016
regulation of protein complex assemblyGO:004325430.016
macromolecule modificationGO:00434121110.016
negative regulation of programmed cell deathGO:0043069580.016
cellular amine metabolic processGO:004410620.016
amine metabolic processGO:000930820.016
regulation of nucleotide catabolic processGO:003081120.016
stem cell maintenanceGO:001982740.016
cellular response to chemical stimulusGO:00708871570.016
somatic stem cell maintenanceGO:003501910.016
skeletal system morphogenesisGO:00487051020.016
regulation of cellular component movementGO:0051270550.016
hepaticobiliary system developmentGO:0061008980.016
membrane invaginationGO:001032410.016
guanosine containing compound metabolic processGO:190106840.016
endothelial cell fate commitmentGO:006083930.016
regulation of protein metabolic processGO:0051246560.016
negative regulation of cellular biosynthetic processGO:0031327550.016
cardiac chamber developmentGO:0003205190.016
negative regulation of rna biosynthetic processGO:1902679450.016
axonogenesisGO:00074091520.016
carbohydrate biosynthetic processGO:001605110.016
cell deathGO:00082191210.015
nuclear transportGO:005116940.015
sequestering of metal ionGO:005123830.015
forebrain developmentGO:0030900960.015
regulation of establishment of planar polarityGO:009017540.015
hormone secretionGO:004687920.015
water homeostasisGO:003010440.015
g1 s transition of mitotic cell cycleGO:000008210.015
positive regulation of mesenchymal cell proliferationGO:000205310.015
autophagyGO:000691440.015
response to carbohydrateGO:000974330.015
phosphatidylinositol 3 kinase signalingGO:001406520.015
cellular response to growth factor stimulusGO:0071363390.015
muscle structure developmentGO:00610611960.015
response to organic substanceGO:00100331530.015
negative regulation of catabolic processGO:000989530.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
response to oxygen levelsGO:0070482250.015
response to drugGO:004249330.015
phosphatidylinositol mediated signalingGO:004801520.015
small molecule metabolic processGO:0044281770.015
epidermal cell fate specificationGO:000995740.015
oxoacid metabolic processGO:0043436310.015
regulation of neuronal synaptic plasticityGO:004816810.015
ear morphogenesisGO:0042471640.015
regulation of inflammatory responseGO:005072720.015
cellular protein modification processGO:00064641000.015
adult behaviorGO:003053420.015
regulation of cardiac muscle tissue developmentGO:005502410.015
myelin assemblyGO:003228810.014
cellular protein metabolic processGO:00442671290.014
positive regulation of cell matrix adhesionGO:000195410.014
locomotor rhythmGO:004547530.014
carbohydrate homeostasisGO:003350010.014
peptidyl lysine acetylationGO:001839420.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.014
regulation of angiogenesisGO:0045765260.014
muscle organ developmentGO:00075171010.014
ovulation cycle processGO:002260220.014
cellular response to organic substanceGO:00713101050.014
positive regulation of epithelial cell migrationGO:001063420.014
regulation of reactive oxygen species metabolic processGO:200037720.014
muscle contractionGO:0006936180.014
actin cytoskeleton organizationGO:0030036630.014
negative chemotaxisGO:005091910.014
cellular response to biotic stimulusGO:007121630.014
regulation of localizationGO:00328791040.014
cilium assemblyGO:0042384580.014
positive regulation of signalingGO:0023056560.014
gland developmentGO:00487321430.014
multicellular organismal response to stressGO:003355520.014
circulatory system processGO:0003013870.014
epithelial tube morphogenesisGO:00605621480.014
peptide transportGO:001583310.014
regulation of cellular ketone metabolic processGO:001056570.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
outflow tract morphogenesisGO:000315110.014
notch signaling pathwayGO:0007219350.014
stem cell divisionGO:001714510.014
negative regulation of cell deathGO:0060548600.013
retina morphogenesis in camera type eyeGO:0060042790.013
regulation of cell developmentGO:00602841000.013
mesenchymal cell proliferationGO:001046310.013
reflexGO:006000420.013
dorsal ventral pattern formationGO:00099531250.013
regulation of cellular component organizationGO:0051128860.013
intracellular mrna localizationGO:000829810.013
response to hydrogen peroxideGO:004254230.013
digestive tract morphogenesisGO:00485462310.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
pigmentationGO:0043473850.013
astrocyte differentiationGO:004870810.013
regulation of heart growthGO:006042020.013
positive regulation of endothelial cell migrationGO:001059520.013
pole plasm assemblyGO:000731540.013
protein modification processGO:00362111000.013
lateral inhibitionGO:004633110.013
hematopoietic progenitor cell differentiationGO:0002244230.013
cell morphogenesis involved in differentiationGO:00009041950.013
macroautophagyGO:001623610.013
positive regulation of transcription dna templatedGO:0045893570.013
lateral line system developmentGO:0048925760.013
regulation of cell motilityGO:2000145460.013
negative regulation of secretionGO:005104820.013
response to hypoxiaGO:0001666250.013
response to other organismGO:0051707970.013
developmental programmed cell deathGO:001062340.013
developmental growthGO:00485891660.013
regulation of protein import into nucleusGO:004230620.013
regulation of protein bindingGO:004339330.013
regulation of gtp catabolic processGO:003312420.013
negative regulation of response to stimulusGO:00485851040.013
positive regulation of lipase activityGO:006019310.013
heart trabecula morphogenesisGO:006138420.013
organonitrogen compound metabolic processGO:1901564740.013
vasculogenesisGO:0001570410.013
homeostatic processGO:00425921420.013
neural crest cell differentiationGO:0014033720.013
biological adhesionGO:0022610400.013
transcription elongation from rna polymerase ii promoterGO:000636830.013
cell migrationGO:00164772370.012
regulation of hematopoietic progenitor cell differentiationGO:190153210.012
deathGO:00162651210.012
ovulation cycleGO:004269820.012
taxisGO:00423301090.012
positive regulation of muscle organ developmentGO:004863610.012
regulation of lipase activityGO:006019120.012
cytoskeleton organizationGO:0007010960.012
response to glucoseGO:000974930.012
negative regulation of sequestering of calcium ionGO:005128340.012
positive regulation of protein complex assemblyGO:003133420.012
organelle fusionGO:004828430.012
negative regulation of epithelial cell proliferationGO:005068010.012
negative regulation of wnt signaling pathwayGO:0030178300.012
positive regulation of blood circulationGO:190352420.012
macromolecular complex subunit organizationGO:0043933740.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
response to hexoseGO:000974630.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
endocardial cushion formationGO:000327220.012
anterior posterior pattern specificationGO:00099521520.012
fertilizationGO:000956630.012
establishment of localization in cellGO:0051649770.012
regulation of ion transmembrane transporter activityGO:003241220.012
multicellular organismal homeostasisGO:0048871290.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
cytosolic calcium ion transportGO:006040130.012
regulation of nucleoside metabolic processGO:000911820.012
cellular carbohydrate metabolic processGO:004426240.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
guanosine containing compound catabolic processGO:190106920.012
neuron projection developmentGO:00311751800.012

ptprja disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.022
musculoskeletal system diseaseDOID:1700.021
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.018
organ system cancerDOID:005068600.013
sensory system diseaseDOID:005015500.012