Danio rerio

14 known processes

si:dkeyp-50f5.1

si:dkeyp-50f5.1

(Aliases: pax1b)

si:dkeyp-50f5.1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
odontogenesis of dentin containing toothGO:004247510.639
cellular component movementGO:00069283350.557
embryonic heart tube developmentGO:00350501330.519
heart developmentGO:00075073130.447
localization of cellGO:00516742440.425
vasculature developmentGO:00019442780.414
regulation of cell differentiationGO:00455951420.349
lymph vessel developmentGO:0001945270.308
regulation of response to stimulusGO:00485832690.278
organic substance biosynthetic processGO:19015762890.271
cell motilityGO:00488702440.263
dorsal ventral pattern formationGO:00099531250.260
negative regulation of biological processGO:00485193040.255
heart morphogenesisGO:00030071560.245
tube morphogenesisGO:00352393490.243
morphogenesis of an epitheliumGO:00020093330.225
regulation of multicellular organismal developmentGO:20000262230.221
regulation of multicellular organismal processGO:00512392770.221
determination of dorsal ventral asymmetryGO:0048262340.215
gastrulationGO:00073692080.214
determination of left right symmetryGO:00073681790.214
signal transductionGO:00071654550.203
determination of bilateral symmetryGO:00098552040.200
negative regulation of kinase activityGO:003367340.199
lymph vessel morphogenesisGO:0036303250.199
regulation of synapse assemblyGO:005196330.194
digestive tract developmentGO:00485652650.193
inner ear developmentGO:00488391260.190
blood vessel developmentGO:00015682460.190
regulation of biological qualityGO:00650082630.188
hard palate developmentGO:006002240.188
response to external stimulusGO:00096052640.179
blood vessel morphogenesisGO:00485142160.173
cellular biosynthetic processGO:00442492860.164
connective tissue developmentGO:0061448990.163
meiotic chromosome segregationGO:004513230.159
cardiac muscle tissue developmentGO:0048738480.153
biosynthetic processGO:00090582940.152
striated muscle tissue developmentGO:00147061100.148
lymphangiogenesisGO:0001946250.144
embryonic organ developmentGO:00485683810.143
positive regulation of biological processGO:00485182530.137
regulation of biosynthetic processGO:00098892500.136
regulation of developmental processGO:00507932470.136
positive regulation of nitrogen compound metabolic processGO:0051173690.133
cartilage developmentGO:0051216960.127
cellular macromolecule metabolic processGO:00442603910.125
digestive system developmentGO:00551232890.121
cellular nitrogen compound biosynthetic processGO:00442712180.119
muscle tissue developmentGO:00605371100.118
renal system developmentGO:0072001940.116
digestive tract morphogenesisGO:00485462310.113
forebrain developmentGO:0030900960.111
stem cell maintenanceGO:001982740.109
inorganic cation transmembrane transportGO:0098662500.107
negative regulation of protein phosphorylationGO:000193340.107
larval developmentGO:000216420.106
aromatic compound biosynthetic processGO:00194382170.105
regulation of gene expressionGO:00104682650.104
regulation of transcription dna templatedGO:00063552130.104
specification of symmetryGO:00097992040.101
positive regulation of cellular component biogenesisGO:004408930.101
regulation of nucleic acid templated transcriptionGO:19035062130.101
regulation of synaptic growth at neuromuscular junctionGO:000858210.099
gene expressionGO:00104672520.097
heart loopingGO:0001947940.097
cellular nitrogen compound metabolic processGO:00346412900.097
cellular amine metabolic processGO:004410620.094
cardiac muscle cell differentiationGO:0055007300.094
enzyme linked receptor protein signaling pathwayGO:00071671060.093
phagocytosisGO:000690930.092
embryonic heart tube morphogenesisGO:00031431080.092
negative regulation of cellular processGO:00485232830.091
skeletal system developmentGO:00015011810.091
convergent extension involved in gastrulationGO:0060027710.090
regulation of metabolic processGO:00192223590.088
nitrogen compound metabolic processGO:00068073190.087
macromolecule biosynthetic processGO:00090592270.087
otic vesicle morphogenesisGO:0071600340.087
regulation of cellular macromolecule biosynthetic processGO:20001122220.086
cellular aromatic compound metabolic processGO:00067252950.085
regulation of protein catabolic processGO:004217610.084
regulation of cellular amine metabolic processGO:003323800.084
regulation of synapse organizationGO:005080730.084
regulation of cellular metabolic processGO:00313233200.083
regulation of primary metabolic processGO:00800903110.083
phosphorus metabolic processGO:00067931090.083
epithelial cell migrationGO:0010631250.083
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.082
regulation of anatomical structure morphogenesisGO:00226031300.081
nucleobase containing compound biosynthetic processGO:00346542050.080
sensory perception of mechanical stimulusGO:0050954160.080
muscle structure developmentGO:00610611960.079
response to bacteriumGO:0009617580.079
stem cell proliferationGO:007208940.078
determination of ventral identityGO:0048264210.078
membrane invaginationGO:001032410.078
wound healingGO:0042060900.078
negative regulation of metabolic processGO:0009892860.077
cellular component biogenesisGO:00440851780.077
determination of heart left right asymmetryGO:00613711170.077
negative regulation of protein kinase activityGO:000646940.074
fin developmentGO:0033333770.072
organic cyclic compound metabolic processGO:19013603010.072
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.072
cell surface receptor signaling pathwayGO:00071663250.072
positive regulation of molecular functionGO:0044093330.072
locomotionGO:00400113130.071
cardiac atrium developmentGO:000323040.071
tissue remodelingGO:004877140.070
cardiac chamber developmentGO:0003205190.070
intracellular signal transductionGO:0035556850.070
modification dependent macromolecule catabolic processGO:004363230.069
ear developmentGO:00435831270.069
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.068
synaptic growth at neuromuscular junctionGO:005112420.068
cell migrationGO:00164772370.067
carbohydrate derivative biosynthetic processGO:1901137430.067
growthGO:00400071740.066
heterocycle metabolic processGO:00464832900.066
urogenital system developmentGO:0001655970.065
regulation of nucleobase containing compound metabolic processGO:00192192500.065
positive regulation of cellular processGO:00485222010.065
determination of dorsal identityGO:0048263130.065
response to organic substanceGO:00100331530.065
cellular macromolecule biosynthetic processGO:00346452240.064
phosphatidylinositol 3 kinase signalingGO:001406520.064
ameboidal type cell migrationGO:00016671430.064
regulation of jun kinase activityGO:004350630.063
embryonic organ morphogenesisGO:00485622740.063
immune system processGO:00023762410.063
regulation of macromolecule metabolic processGO:00602553170.063
cilium movementGO:0003341260.062
regulation of localizationGO:00328791040.062
positive regulation of synapse assemblyGO:005196510.062
single organism cell adhesionGO:0098602290.062
organophosphate biosynthetic processGO:0090407230.061
phosphatidylinositol mediated signalingGO:004801520.061
modification dependent protein catabolic processGO:001994130.060
positive regulation of gene expressionGO:0010628710.059
angiogenesisGO:00015251580.059
regulation of nitrogen compound metabolic processGO:00511712510.059
synaptic transmissionGO:0007268350.059
regulation of cellular amino acid metabolic processGO:000652100.058
regulation of signalingGO:00230512350.058
response to chemicalGO:00422213200.058
cell migration involved in gastrulationGO:0042074790.057
cell morphogenesisGO:00009022890.057
positive regulation of catabolic processGO:000989640.057
immune system developmentGO:00025201910.056
phosphorylationGO:0016310690.055
rna biosynthetic processGO:00327741810.055
gland developmentGO:00487321430.055
single organism metabolic processGO:00447102170.055
positive regulation of map kinase activityGO:004340630.054
ubiquitin dependent protein catabolic processGO:000651130.054
regulation of wound healingGO:006104120.053
inositol lipid mediated signalingGO:004801720.053
regulation of cellular biosynthetic processGO:00313262450.053
meiotic nuclear divisionGO:000712640.052
positive regulation of macromolecule metabolic processGO:0010604930.052
heterocycle biosynthetic processGO:00181302150.052
erk1 and erk2 cascadeGO:007037140.051
maintenance of locationGO:005123540.051
cytokinesisGO:000091030.051
septum transversum developmentGO:000334340.050
organic acid metabolic processGO:0006082310.050
regulation of axonogenesisGO:0050770320.050
regulation of cellular component organizationGO:0051128860.050
nucleobase containing compound metabolic processGO:00061392740.049
positive regulation of cell cycleGO:004578730.049
otolith developmentGO:0048840320.049
positive regulation of epithelial cell differentiationGO:003085820.049
fin morphogenesisGO:0033334530.049
negative regulation of phosphate metabolic processGO:0045936130.049
establishment of organelle localizationGO:0051656450.048
regulation of molecular functionGO:0065009700.048
cellular response to chemical stimulusGO:00708871570.048
meiotic cell cycle processGO:190304630.047
positive regulation of macromolecule biosynthetic processGO:0010557590.047
regulation of cell activationGO:005086510.046
cellular response to endogenous stimulusGO:0071495680.046
positive regulation of rna metabolic processGO:0051254590.046
translational initiationGO:000641330.046
regulation of rna metabolic processGO:00512522240.045
regulation of catalytic activityGO:0050790550.045
cellular amino acid metabolic processGO:000652070.044
negative regulation of macromolecule metabolic processGO:0010605760.044
central nervous system developmentGO:00074173870.044
positive regulation of response to stimulusGO:0048584800.044
regulation of macromolecule biosynthetic processGO:00105562250.042
single organism organelle organizationGO:19025891990.042
cellular protein catabolic processGO:004425740.042
signal transduction by p53 class mediatorGO:0072331130.042
amine metabolic processGO:000930820.041
cytoskeleton organizationGO:0007010960.041
regulation of transcription from rna polymerase ii promoterGO:00063571140.041
agingGO:000756820.041
negative regulation of map kinase activityGO:004340720.041
regulation of blood vessel sizeGO:005088020.041
transcription dna templatedGO:00063511810.041
peripheral nervous system developmentGO:0007422550.041
heart joggingGO:0003146400.041
kidney developmentGO:0001822920.040
cellular protein modification processGO:00064641000.040
carboxylic acid metabolic processGO:0019752220.040
stem cell divisionGO:001714510.039
regulation of muscle tissue developmentGO:190186160.039
post embryonic morphogenesisGO:000988640.039
mitotic cell cycleGO:0000278640.039
proteolysis involved in cellular protein catabolic processGO:005160330.038
nucleic acid templated transcriptionGO:00976591810.038
appendage morphogenesisGO:0035107560.038
oxoacid metabolic processGO:0043436310.038
regulation of rna biosynthetic processGO:20011412130.038
phosphate containing compound metabolic processGO:00067961080.037
artery developmentGO:0060840220.037
positive regulation of cellular catabolic processGO:003133130.037
response to steroid hormoneGO:0048545350.037
regulation of neurogenesisGO:0050767870.037
negative regulation of immune responseGO:005077720.037
establishment of localizationGO:00512342440.037
vestibular receptor cell developmentGO:006011830.036
regulation of cell developmentGO:00602841000.036
positive regulation of locomotionGO:0040017140.035
regulation of cellular protein metabolic processGO:0032268520.035
response to woundingGO:00096111160.035
cellular component assemblyGO:00226071700.035
head developmentGO:00603223030.035
protein complex localizationGO:003150310.035
cell proliferationGO:0008283800.035
phagocytosis engulfmentGO:000691110.035
actin filament based movementGO:003004810.034
microtubule based processGO:0007017600.034
organic cyclic compound biosynthetic processGO:19013622230.034
cellular ketone metabolic processGO:0042180110.033
regulation of anatomical structure sizeGO:0090066330.033
transcription from rna polymerase ii promoterGO:0006366800.033
glycerophospholipid biosynthetic processGO:004647410.033
rna metabolic processGO:00160702190.032
embryonic limb morphogenesisGO:003032620.032
neuron projection extensionGO:1990138450.032
positive regulation of cellular component movementGO:0051272110.031
positive regulation of transcription dna templatedGO:0045893570.031
negative regulation of innate immune responseGO:004582420.031
cell cell signalingGO:0007267520.030
axon developmentGO:00615641660.030
regulation of cellular ketone metabolic processGO:001056570.030
regulation of blood coagulationGO:003019310.030
regenerationGO:0031099910.029
regulation of mesenchymal cell proliferationGO:001046410.029
regulation of erk1 and erk2 cascadeGO:007037240.029
cell deathGO:00082191210.029
transmembrane transportGO:00550851200.029
embryo development ending in birth or egg hatchingGO:00097922710.029
spinal cord anterior posterior patterningGO:002151210.029
actin cytoskeleton organizationGO:0030036630.028
regulation of neurotransmitter secretionGO:004692810.028
germ line stem cell maintenanceGO:003071820.028
regulation of autophagyGO:001050630.028
regulation of tube sizeGO:003515020.028
amino acid transportGO:000686520.028
neuroblast proliferationGO:000740520.027
cellular carbohydrate metabolic processGO:004426240.027
blood circulationGO:0008015870.027
sensory organ developmentGO:00074233930.027
water homeostasisGO:003010440.027
regulation of neuron differentiationGO:0045664560.027
macromolecule modificationGO:00434121110.027
regulation of coagulationGO:005081820.027
determination of left right asymmetry in nervous systemGO:003554540.027
trabecula formationGO:006034320.027
synapse organizationGO:0050808210.027
endothelial cell migrationGO:0043542190.026
caudal fin morphogenesisGO:003514370.026
response to stressGO:00069502630.026
regulation of peptidyl tyrosine phosphorylationGO:005073010.026
endoderm formationGO:0001706290.026
defense response to other organismGO:0098542330.026
positive regulation of epithelial cell proliferationGO:005067910.026
multi organism processGO:00517041340.025
regionalizationGO:00030022740.025
negative regulation of epithelial cell proliferationGO:005068010.025
negative regulation of nucleobase containing compound metabolic processGO:0045934590.025
cellular response to radiationGO:007147840.025
cell part morphogenesisGO:00329902460.025
regulation of mesoderm developmentGO:2000380110.025
positive regulation of biosynthetic processGO:0009891680.025
response to abiotic stimulusGO:00096281220.025
regulation of locomotionGO:0040012550.025
positive regulation of metabolic processGO:00098931080.025
positive regulation of erk1 and erk2 cascadeGO:007037420.025
tissue migrationGO:0090130370.025
organelle localizationGO:0051640490.025
negative regulation of gene expressionGO:0010629650.025
cardiocyte differentiationGO:0035051440.025
hemopoiesisGO:00300971830.025
positive regulation of cellular protein metabolic processGO:0032270220.025
diencephalon developmentGO:0021536580.024
hepaticobiliary system developmentGO:0061008980.024
proteasomal protein catabolic processGO:001049820.024
neurotransmitter transportGO:000683620.024
odontogenesisGO:004247690.024
regulation of neurotransmitter transportGO:005158810.024
exocytosisGO:000688710.024
positive regulation of cellular metabolic processGO:0031325940.024
regulation of cell communicationGO:00106462320.024
response to biotic stimulusGO:0009607970.024
cardiac cell developmentGO:0055006210.024
cellular protein metabolic processGO:00442671290.024
pathway restricted smad protein phosphorylationGO:006038910.023
lipid metabolic processGO:0006629520.023
regulation of angiogenesisGO:0045765260.023
positive regulation of catalytic activityGO:0043085250.023
protein metabolic processGO:00195381830.023
axonogenesisGO:00074091520.023
skin developmentGO:0043588540.023
regulation of inflammatory responseGO:005072720.023
regulation of peptidase activityGO:0052547230.023
regulation of multicellular organism growthGO:004001440.023
rhombomere 5 developmentGO:002157140.023
defense response to bacteriumGO:0042742220.023
negative regulation of developmental processGO:0051093650.023
regulation of bone remodelingGO:004685020.023
negative regulation of calcium dependent cell cell adhesionGO:004658810.022
regulation of phosphate metabolic processGO:0019220430.022
organonitrogen compound metabolic processGO:1901564740.022
regulation of response to stressGO:0080134360.022
vestibular receptor cell differentiationGO:006011430.022
generation of neuronsGO:00486993850.022
cell fate commitmentGO:0045165990.022
inorganic ion transmembrane transportGO:0098660570.022
hematopoietic or lymphoid organ developmentGO:00485341910.022
regulation of proteolysisGO:0030162240.022
regulation of protein metabolic processGO:0051246560.022
spindle localizationGO:0051653120.022
cardiac muscle cell developmentGO:0055013200.021
neurotransmitter secretionGO:000726920.021
transforming growth factor beta receptor signaling pathwayGO:000717970.021
nucleic acid metabolic processGO:00903042440.021
cellular response to hypoxiaGO:007145610.021
regulation of establishment or maintenance of cell polarityGO:003287820.021
taxisGO:00423301090.021
macromolecular complex subunit organizationGO:0043933740.021
regulation of organ morphogenesisGO:2000027350.021
outflow tract morphogenesisGO:000315110.021
mesenchymal cell proliferationGO:001046310.021
cation transportGO:0006812810.020
epithelial tube morphogenesisGO:00605621480.020
neuromuscular synaptic transmissionGO:000727420.020
neuron neuron synaptic transmissionGO:000727010.020
positive regulation of cellular biosynthetic processGO:0031328680.020
response to external biotic stimulusGO:0043207970.020
kupffer s vesicle developmentGO:0070121500.020
single organismal cell cell adhesionGO:0016337290.020
positive regulation of i kappab kinase nf kappab signalingGO:004312330.020
cell growthGO:0016049570.020
negative regulation of biosynthetic processGO:0009890550.019
trabecula morphogenesisGO:006138320.019
organelle organizationGO:00069962270.019
positive regulation of signal transductionGO:0009967560.019
cellular component assembly involved in morphogenesisGO:00109271070.019
complement activationGO:000695630.019
regulation of receptor activityGO:001046920.019
regulation of calcium dependent cell cell adhesionGO:004658610.019
positive regulation of muscle organ developmentGO:004863610.019
endodermal cell fate commitmentGO:0001711180.019
cytokinetic processGO:003250620.019
regulation of transferase activityGO:0051338160.019
morphogenesis of an epithelial sheetGO:0002011490.019
multicellular organism growthGO:003526440.018
protein modification processGO:00362111000.018
positive regulation of transportGO:005105020.018
negative regulation of defense responseGO:003134820.018
proteolysisGO:0006508380.018
regulation of hemostasisGO:190004610.018
system processGO:00030081850.018
muscle organ developmentGO:00075171010.018
cell projection morphogenesisGO:00488582440.018
response to growth factorGO:0070848390.018
positive regulation of cytoskeleton organizationGO:005149530.018
defense responseGO:0006952470.018
patterning of blood vesselsGO:0001569150.018
central nervous system formationGO:002155610.017
immune responseGO:0006955280.017
response to endogenous stimulusGO:0009719830.017
regulation of endothelial cell differentiationGO:004560130.017
microtubule based movementGO:0007018330.017
negative regulation of phosphorus metabolic processGO:0010563130.017
segmentationGO:0035282970.017
epidermis developmentGO:0008544480.017
negative regulation of cellular metabolic processGO:0031324770.017
phosphatidylinositol biosynthetic processGO:000666110.017
actin polymerization or depolymerizationGO:000815420.017
single organism localizationGO:19025782250.017
protein complex biogenesisGO:0070271300.017
negative regulation of mapk cascadeGO:004340940.017
epithelium migrationGO:0090132250.017
positive regulation of rna biosynthetic processGO:1902680570.016
sensory organ morphogenesisGO:00905962000.016
negative regulation of synapse assemblyGO:005196420.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
lipid homeostasisGO:005508830.016
negative regulation of protein serine threonine kinase activityGO:007190120.016
mesoderm developmentGO:0007498880.016
circulatory system processGO:0003013870.016
somite developmentGO:0061053960.016
neuron differentiationGO:00301823530.016
regulation of phosphorus metabolic processGO:0051174430.016
embryonic cranial skeleton morphogenesisGO:0048701900.015
regulation of cell shapeGO:000836010.015
negative regulation of mitosisGO:004583930.015
regulation of cell proliferationGO:0042127370.015
regulation of cellular component movementGO:0051270550.015
regulation of epidermis developmentGO:004568220.015
female sex differentiationGO:004666040.015
regulation of muscle organ developmentGO:004863490.015
positive regulation of dna metabolic processGO:005105410.015
regulation of cell cycleGO:0051726520.015
regulation of bindingGO:005109830.015
positive regulation of nucleobase containing compound metabolic processGO:0045935690.015
regulation of protein targetingGO:190353320.015
skeletal system morphogenesisGO:00487051020.015
regulation of myotube differentiationGO:001083020.015
axon extensionGO:0048675450.014
negative regulation of multicellular organismal processGO:0051241690.014
positive regulation of cell adhesionGO:004578510.014
regulation of cell motilityGO:2000145460.014
homeostatic processGO:00425921420.014
ion transmembrane transportGO:0034220910.014
morphogenesis of a branching structureGO:0001763210.014
notochord developmentGO:0030903540.014
dna metabolic processGO:0006259270.014
developmental cell growthGO:0048588520.014
regulation of protein kinase activityGO:0045859150.014
cellular response to growth factor stimulusGO:0071363390.014
regulation of cell morphogenesisGO:0022604420.014
cellular response to hormone stimulusGO:0032870390.014
positive regulation of cytosolic calcium ion concentrationGO:000720440.014
regulation of translational initiationGO:000644610.014
regulation of kinase activityGO:0043549150.014
calcium ion importGO:007050940.014
apoptotic process involved in morphogenesisGO:006056120.014
positive regulation of cellular amine metabolic processGO:003324000.014
cation transmembrane transportGO:0098655650.014
chemotaxisGO:00069351040.014
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.013
cellular response to oxygen levelsGO:007145310.013
protein complex subunit organizationGO:0071822460.013
actin filament based processGO:0030029640.013
cellular response to organic substanceGO:00713101050.013
cell projection organizationGO:00300302840.013
appendage developmentGO:0048736800.013
regulation of signal transductionGO:00099662250.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
calcium ion transmembrane transportGO:0070588130.013
regulation of biomineral tissue developmentGO:007016720.013
negative regulation of angiogenesisGO:001652570.013
neuron projection developmentGO:00311751800.013
negative regulation of cellular biosynthetic processGO:0031327550.013
regulation of cellular protein catabolic processGO:190336210.013
determination of left right asymmetry in diencephalonGO:003546240.013
muscle cell migrationGO:001481240.013
transportGO:00068102200.013
synapse assemblyGO:000741690.013
regulation of body fluid levelsGO:0050878160.013
nucleocytoplasmic transportGO:000691340.013
regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:190225350.012
regulation of i kappab kinase nf kappab signalingGO:004312240.012
protein acetylationGO:000647320.012
behaviorGO:0007610740.012
endodermal cell fate determinationGO:000749320.012
regulation of axon guidanceGO:190266780.012
mechanosensory behaviorGO:000763820.012
regulation of tissue remodelingGO:003410320.012
intracellular receptor signaling pathwayGO:0030522300.012
negative regulation of transcription dna templatedGO:0045892450.012
response to uvGO:000941130.012
regulation of neuron projection developmentGO:0010975400.012
muscle cell differentiationGO:00426921390.012
regulation of metal ion transportGO:001095940.012
reflexGO:006000420.012
regulation of endopeptidase activityGO:0052548230.012
activation of immune responseGO:000225390.012
negative regulation of jnk cascadeGO:004632910.012
dorsal convergenceGO:0060030140.012
negative chemotaxisGO:005091910.012
autophagyGO:000691440.012
regulation of axon extensionGO:0030516240.012
detection of abiotic stimulusGO:0009582240.012
protein localization to nucleusGO:003450430.012
establishment of spindle localizationGO:0051293120.012
cell adhesionGO:0007155400.011
regulation of stem cell differentiationGO:200073640.011
motor neuron axon guidanceGO:0008045230.011

si:dkeyp-50f5.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
disease of cellular proliferationDOID:1456600.018
organ system cancerDOID:005068600.018
cancerDOID:16200.018