Danio rerio

0 known processes

hpd

4-hydroxyphenylpyruvate dioxygenase

(Aliases: hpdb,zgc:92456)

hpd biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of multicellular organismal processGO:00512392770.219
eye developmentGO:00016542770.173
cell surface receptor signaling pathwayGO:00071663250.146
sensory organ developmentGO:00074233930.144
skeletal system developmentGO:00015011810.141
regulation of cell differentiationGO:00455951420.107
digestive tract morphogenesisGO:00485462310.104
morphogenesis of an epitheliumGO:00020093330.099
regulation of developmental processGO:00507932470.095
signal transductionGO:00071654550.095
regulation of signal transductionGO:00099662250.090
regulation of response to stimulusGO:00485832690.088
regulation of multicellular organismal developmentGO:20000262230.088
negative regulation of response to stimulusGO:00485851040.080
generation of neuronsGO:00486993850.079
regulation of reproductive processGO:200024140.077
cell substrate adhesionGO:003158940.076
heart developmentGO:00075073130.073
regulation of cell shapeGO:000836010.072
regulation of neurogenesisGO:0050767870.071
cell migrationGO:00164772370.069
larval developmentGO:000216420.068
positive regulation of transportGO:005105020.066
vasculature developmentGO:00019442780.065
regulation of hormone secretionGO:004688320.065
regulation of stem cell differentiationGO:200073640.061
tube morphogenesisGO:00352393490.061
regulation of neuron differentiationGO:0045664560.059
regulation of cell developmentGO:00602841000.058
cellular component movementGO:00069283350.057
protein localization to nucleusGO:003450430.056
locomotionGO:00400113130.055
positive regulation of cell differentiationGO:0045597300.055
regulation of signalingGO:00230512350.055
negative regulation of small gtpase mediated signal transductionGO:005105810.054
organic substance biosynthetic processGO:19015762890.052
cell motilityGO:00488702440.048
cartilage developmentGO:0051216960.047
biological adhesionGO:0022610400.047
digestive tract developmentGO:00485652650.046
ameboidal type cell migrationGO:00016671430.045
regulation of nervous system developmentGO:0051960900.045
regulation of cell substrate adhesionGO:001081010.044
cell fate commitmentGO:0045165990.043
localization of cellGO:00516742440.042
specification of symmetryGO:00097992040.042
regulation of anatomical structure morphogenesisGO:00226031300.041
cell fate specificationGO:0001708680.040
cell morphogenesis involved in differentiationGO:00009041950.040
hormone transportGO:000991420.040
regulation of synapse assemblyGO:005196330.039
positive regulation of developmental processGO:0051094500.039
regulation of cellular biosynthetic processGO:00313262450.039
hematopoietic or lymphoid organ developmentGO:00485341910.039
regulation of establishment of protein localizationGO:007020140.039
cell part morphogenesisGO:00329902460.038
negative regulation of cellular processGO:00485232830.038
nuclear transportGO:005116940.038
gastrulationGO:00073692080.038
regulation of cell communicationGO:00106462320.038
cell adhesionGO:0007155400.038
nucleocytoplasmic transportGO:000691340.037
negative regulation of biological processGO:00485193040.036
biosynthetic processGO:00090582940.036
peptide transportGO:001583310.036
regulation of intracellular protein transportGO:003315730.035
nucleic acid metabolic processGO:00903042440.035
multicellular organism growthGO:003526440.035
regulation of gene expressionGO:00104682650.035
digestive system developmentGO:00551232890.034
nucleobase containing compound biosynthetic processGO:00346542050.034
regulation of locomotionGO:0040012550.034
protein importGO:001703830.034
positive regulation of stress activated mapk cascadeGO:003287430.034
hormone secretionGO:004687920.033
cellular nitrogen compound biosynthetic processGO:00442712180.033
regulation of biosynthetic processGO:00098892500.033
nucleic acid templated transcriptionGO:00976591810.033
positive regulation of cell adhesionGO:004578510.033
nuclear importGO:005117030.033
regulation of synapse organizationGO:005080730.032
lateral inhibitionGO:004633110.032
regulation of cellular macromolecule biosynthetic processGO:20001122220.032
organelle assemblyGO:00709251100.032
embryonic organ morphogenesisGO:00485622740.032
regulation of nucleocytoplasmic transportGO:004682220.032
cellular component biogenesisGO:00440851780.032
organic cyclic compound biosynthetic processGO:19013622230.031
positive regulation of biological processGO:00485182530.031
convergent extensionGO:00600261180.031
blood vessel morphogenesisGO:00485142160.031
cognitionGO:005089010.031
macromolecule biosynthetic processGO:00090592270.030
epithelial cell migrationGO:0010631250.030
cellular macromolecule biosynthetic processGO:00346452240.029
head developmentGO:00603223030.029
regulation of primary metabolic processGO:00800903110.029
positive regulation of cellular processGO:00485222010.028
immune system processGO:00023762410.028
chordate embryonic developmentGO:00430092710.028
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.028
muscle tissue developmentGO:00605371100.028
angiogenesisGO:00015251580.028
formation of primary germ layerGO:0001704620.028
positive regulation of cell substrate adhesionGO:001081110.027
small molecule catabolic processGO:004428230.027
neuron differentiationGO:00301823530.027
cell morphogenesisGO:00009022890.027
regulation of protein transportGO:005122330.027
regulation of protein targetingGO:190353320.027
embryonic organ developmentGO:00485683810.027
glucose homeostasisGO:004259310.026
mesenchymal cell developmentGO:0014031780.026
regulation of cellular component movementGO:0051270550.026
agingGO:000756820.026
Worm
regulation of multicellular organism growthGO:004001440.026
regulation of protein localization to nucleusGO:190018020.026
regulation of metabolic processGO:00192223590.026
regulation of macromolecule biosynthetic processGO:00105562250.025
developmental growthGO:00485891660.025
protein targeting to nucleusGO:004474430.025
nitrogen compound metabolic processGO:00068073190.025
gland developmentGO:00487321430.025
cellular macromolecule metabolic processGO:00442603910.024
positive regulation of canonical wnt signaling pathwayGO:009026340.024
stem cell maintenanceGO:001982740.024
mesenchyme developmentGO:00604851270.024
cellular nitrogen compound metabolic processGO:00346412900.023
response to drugGO:004249330.023
negative regulation of synapse assemblyGO:005196420.023
organic acid metabolic processGO:0006082310.023
brain developmentGO:00074202930.023
mononuclear cell proliferationGO:003294310.023
epithelium migrationGO:0090132250.023
single organism nuclear importGO:190259330.023
germ line stem cell maintenanceGO:003071820.023
establishment of protein localization to organelleGO:007259440.022
sprouting angiogenesisGO:0002040530.022
regulation of nucleobase containing compound metabolic processGO:00192192500.022
positive regulation of signal transductionGO:0009967560.022
activation of mapk activityGO:000018730.022
blood vessel endothelial cell migrationGO:0043534180.022
positive regulation of locomotionGO:0040017140.022
outflow tract morphogenesisGO:000315110.022
regulation of cell activationGO:005086510.022
eye morphogenesisGO:00485921440.022
oxoacid metabolic processGO:0043436310.021
positive regulation of jnk cascadeGO:004633030.021
protein metabolic processGO:00195381830.021
negative regulation of ras protein signal transductionGO:004658010.021
cellular response to organic substanceGO:00713101050.021
embryonic heart tube developmentGO:00350501330.021
regulation of cytoplasmic transportGO:190364940.021
endothelial cell migrationGO:0043542190.021
cellular component morphogenesisGO:00329893360.020
cellular amino acid metabolic processGO:000652070.020
regionalizationGO:00030022740.020
connective tissue developmentGO:0061448990.020
central nervous system developmentGO:00074173870.020
transcription from rna polymerase ii promoterGO:0006366800.020
regulation of rna biosynthetic processGO:20011412130.020
release of sequestered calcium ion into cytosolGO:005120930.020
regulation of rna metabolic processGO:00512522240.020
positive regulation of cellular component biogenesisGO:004408930.020
developmental growth involved in morphogenesisGO:0060560860.020
single organism metabolic processGO:00447102170.020
cellular response to chemical stimulusGO:00708871570.020
regulation of macromolecule metabolic processGO:00602553170.020
sensory perception of chemical stimulusGO:000760630.020
negative regulation of chemotaxisGO:005092240.019
extrinsic apoptotic signaling pathwayGO:009719130.019
carbohydrate homeostasisGO:003350010.019
positive regulation of multicellular organismal processGO:0051240520.019
lymphocyte proliferationGO:004665110.019
carboxylic acid metabolic processGO:0019752220.019
tissue migrationGO:0090130370.019
axonogenesisGO:00074091520.019
mesenchymal cell differentiationGO:0048762870.019
response to glucoseGO:000974930.019
extracellular structure organizationGO:0043062270.019
regulation of cell motilityGO:2000145460.019
response to carbohydrateGO:000974330.018
cellular aromatic compound metabolic processGO:00067252950.018
transcription dna templatedGO:00063511810.018
regulation of sequestering of calcium ionGO:005128240.018
camera type eye developmentGO:00430102220.018
negative regulation of sequestering of calcium ionGO:005128340.018
aromatic compound biosynthetic processGO:00194382170.018
negative regulation of catabolic processGO:000989530.018
positive regulation of cell developmentGO:0010720250.018
response to hexoseGO:000974630.018
amine metabolic processGO:000930820.018
nucleobase containing compound metabolic processGO:00061392740.018
single organism localizationGO:19025782250.018
rna biosynthetic processGO:00327741810.018
negative chemotaxisGO:005091910.018
positive regulation of response to stimulusGO:0048584800.017
mesodermal cell differentiationGO:0048333210.017
response to organic substanceGO:00100331530.017
stem cell proliferationGO:007208940.017
positive regulation of synapse assemblyGO:005196510.017
positive regulation of secretionGO:005104710.017
forebrain cell migrationGO:002188510.017
negative regulation of cell differentiationGO:0045596460.017
cell cycle g1 s phase transitionGO:004484310.017
regulation of erk1 and erk2 cascadeGO:007037240.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
protein polymerizationGO:005125840.017
response to monosaccharideGO:003428430.017
stem cell developmentGO:0048864820.017
striated muscle cell developmentGO:00550021080.017
regulation of transcription dna templatedGO:00063552130.017
internal peptidyl lysine acetylationGO:001839320.017
regulation of protein catabolic processGO:004217610.017
sequestering of metal ionGO:005123830.017
establishment of organelle localizationGO:0051656450.016
cell matrix adhesionGO:000716040.016
regulation of behaviorGO:0050795240.016
regulation of transcription from rna polymerase ii promoterGO:00063571140.016
chemotaxisGO:00069351040.016
regulation of rho protein signal transductionGO:003502320.016
blood vessel developmentGO:00015682460.016
stem cell differentiationGO:00488631170.016
regulation of cellular ketone metabolic processGO:001056570.016
cellular protein metabolic processGO:00442671290.016
heterocycle biosynthetic processGO:00181302150.016
endocrine system developmentGO:0035270650.016
programmed cell deathGO:00125011190.016
regulation of biomineral tissue developmentGO:007016720.016
hard palate developmentGO:006002240.016
production of molecular mediator of immune responseGO:000244020.015
negative regulation of signalingGO:0023057960.015
regulation of cellular component organizationGO:0051128860.015
regulation of dendrite developmentGO:005077330.015
endosomal transportGO:001619720.015
negative regulation of multicellular organismal processGO:0051241690.015
rna metabolic processGO:00160702190.015
positive regulation of nervous system developmentGO:0051962250.015
immune system developmentGO:00025201910.015
g protein coupled receptor signaling pathwayGO:0007186740.015
regulation of dna replicationGO:000627530.015
regulation of programmed cell deathGO:00430671010.015
response to stressGO:00069502630.015
defense response to fungusGO:005083220.015
protein acylationGO:004354330.015
response to nutrientGO:000758430.015
multicellular organismal metabolic processGO:004423620.015
response to growth factorGO:0070848390.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
negative regulation of axon extension involved in axon guidanceGO:004884310.014
phagocytosisGO:000690930.014
negative regulation of developmental processGO:0051093650.014
signal transduction in absence of ligandGO:003803410.014
multicellular organismal macromolecule metabolic processGO:004425920.014
cellular component assemblyGO:00226071700.014
gene expressionGO:00104672520.014
cellular biosynthetic processGO:00442492860.014
embryo development ending in birth or egg hatchingGO:00097922710.014
positive regulation of secretion by cellGO:190353210.014
immunoglobulin mediated immune responseGO:001606430.014
regulation of blood vessel sizeGO:005088020.014
positive regulation of cell communicationGO:0010647560.014
taxisGO:00423301090.014
embryonic skeletal system developmentGO:0048706970.014
regulation of localizationGO:00328791040.014
maintenance of locationGO:005123540.014
behaviorGO:0007610740.014
neuron projection guidanceGO:0097485860.014
regulation of cellular response to growth factor stimulusGO:0090287350.014
ear developmentGO:00435831270.014
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.014
regulation of apoptotic processGO:0042981980.014
synaptic growth at neuromuscular junctionGO:005112420.013
regulation of cellular amine metabolic processGO:003323800.013
erk1 and erk2 cascadeGO:007037140.013
homeostatic processGO:00425921420.013
response to external stimulusGO:00096052640.013
negative regulation of cell communicationGO:0010648960.013
response to vitaminGO:003327330.013
heterocycle metabolic processGO:00464832900.013
regulation of bindingGO:005109830.013
positive regulation of rna metabolic processGO:0051254590.013
skeletal muscle organ developmentGO:0060538780.013
regulation of biological qualityGO:00650082630.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
cellular response to endogenous stimulusGO:0071495680.013
response to chemicalGO:00422213200.013
kupffer s vesicle developmentGO:0070121500.013
apoptotic processGO:00069151160.013
response to corticosteroidGO:003196010.013
regulation of cellular amino acid metabolic processGO:000652100.013
positive regulation of protein complex assemblyGO:003133420.013
cell morphogenesis involved in neuron differentiationGO:00486671630.013
b cell mediated immunityGO:001972430.013
regulation of cellular metabolic processGO:00313233200.013
protein localization to plasma membraneGO:007265910.013
multi organism cellular processGO:004476420.013
neuron projection extensionGO:1990138450.013
proteasomal protein catabolic processGO:001049820.012
regulation of protein complex assemblyGO:004325430.012
negative regulation of dna metabolic processGO:005105340.012
sequestering of calcium ionGO:005120830.012
negative regulation of rho protein signal transductionGO:003502410.012
post embryonic organ developmentGO:004856940.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.012
cellular amine metabolic processGO:004410620.012
positive regulation of cell activationGO:005086710.012
organic cyclic compound metabolic processGO:19013603010.012
multi organism processGO:00517041340.012
regulation of canonical wnt signaling pathwayGO:0060828340.012
g1 s transition of mitotic cell cycleGO:000008210.012
single organism transportGO:00447652060.012
nuclear migrationGO:000709730.012
regulation of cell migrationGO:0030334400.012
protein acetylationGO:000647320.012
regulation of nitrogen compound metabolic processGO:00511712510.012
positive regulation of immune effector processGO:000269930.012
positive regulation of macromolecule biosynthetic processGO:0010557590.012
axon developmentGO:00615641660.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
organic acid catabolic processGO:001605430.012
leukocyte proliferationGO:007066110.011
positive regulation of macromolecule metabolic processGO:0010604930.011
synaptic target recognitionGO:000803910.011
cell adhesion mediated by integrinGO:003362710.011
response to abiotic stimulusGO:00096281220.011
regulation of cell morphogenesisGO:0022604420.011
cellular ketone metabolic processGO:0042180110.011
striated muscle cell differentiationGO:00511461290.011
muscle cell migrationGO:001481240.011
positive regulation of cytokine productionGO:000181920.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
phenol containing compound biosynthetic processGO:004618940.011
protein dephosphorylationGO:000647030.011
axon extensionGO:0048675450.011
regulation of glucose transportGO:001082710.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
cellular response to nutrient levelsGO:003166920.011
cellular transition metal ion homeostasisGO:004691630.011
response to endogenous stimulusGO:0009719830.011
positive regulation of multi organism processGO:004390230.011
regulation of cell morphogenesis involved in differentiationGO:0010769380.011
myeloid cell differentiationGO:0030099860.011
rna localizationGO:000640340.011
regulation of bone mineralizationGO:003050020.011
positive regulation of transcription dna templatedGO:0045893570.011
muscle cell differentiationGO:00426921390.011
negative regulation of cytokine productionGO:000181810.011
larval heart developmentGO:000750820.011
determination of bilateral symmetryGO:00098552040.011
positive regulation of map kinase activityGO:004340630.011
pathway restricted smad protein phosphorylationGO:006038910.011
establishment of blood brain barrierGO:006085620.011
negative regulation of cellular component movementGO:0051271180.011
positive regulation of rna biosynthetic processGO:1902680570.011
positive regulation of neuron differentiationGO:0045666120.011
protein complex subunit organizationGO:0071822460.011
regulation of organelle assemblyGO:190211540.011
exocrine system developmentGO:0035272280.011
positive regulation of reproductive processGO:200024320.011
peptidyl lysine acetylationGO:001839420.011
atp catabolic processGO:000620040.010
collagen metabolic processGO:003296320.010
positive regulation of catabolic processGO:000989640.010
viral processGO:001603210.010
negative regulation of programmed cell deathGO:0043069580.010
epithelial to mesenchymal transitionGO:0001837210.010
glial cell migrationGO:000834730.010
cell projection morphogenesisGO:00488582440.010
negative regulation of neurogenesisGO:0050768200.010
regulation of calcium ion transportGO:005192420.010
organelle organizationGO:00069962270.010
internal protein amino acid acetylationGO:000647520.010
cell deathGO:00082191210.010
cellular protein catabolic processGO:004425740.010
response to glucocorticoidGO:005138410.010
notochord developmentGO:0030903540.010
cell migration involved in heart developmentGO:0060973220.010
b cell activationGO:004211320.010
cellular response to oxygen levelsGO:007145310.010
cellular response to external stimulusGO:007149620.010
negative regulation of myeloid cell differentiationGO:004563810.010
positive regulation of cytoskeleton organizationGO:005149530.010
cellular response to growth factor stimulusGO:0071363390.010
myofibril assemblyGO:0030239480.010
positive regulation of biosynthetic processGO:0009891680.010

hpd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.051
musculoskeletal system diseaseDOID:1700.040
nervous system diseaseDOID:86300.023
cardiovascular system diseaseDOID:128700.020
connective tissue diseaseDOID:6500.015
bone diseaseDOID:008000100.014
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012
eye diseaseDOID:561400.012
muscle tissue diseaseDOID:6600.011
muscular diseaseDOID:008000000.011
myopathyDOID:42300.011
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011