Danio rerio

10 known processes

usp5

ubiquitin specific protease 5

(Aliases: zgc:76990,wu:fb36d11,wu:fa06b05,wu:fc61g08,wu:fc21h02,wu:fi41g10)

usp5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.780
ubiquitin dependent protein catabolic processGO:000651130.630
Human Fly
regulation of primary metabolic processGO:00800903110.621
Human
regulation of protein catabolic processGO:004217610.486
Human
regulation of gene expressionGO:00104682650.485
regulation of macromolecule metabolic processGO:00602553170.477
Human
agingGO:000756820.476
proteolysis involved in cellular protein catabolic processGO:005160330.471
Human Fly
regulation of metabolic processGO:00192223590.464
Human
cellular protein catabolic processGO:004425740.431
Human Fly
gene expressionGO:00104672520.389
organelle fissionGO:0048285230.383
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.373
Human Fly
cellular macromolecule metabolic processGO:00442603910.347
Human Fly
proteasomal protein catabolic processGO:001049820.321
Human Fly
maintenance of locationGO:005123540.318
regulation of cellular protein catabolic processGO:190336210.278
Human
mitotic nuclear divisionGO:0007067180.273
modification dependent protein catabolic processGO:001994130.258
Human Fly
ribonucleoside monophosphate catabolic processGO:000915840.254
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.227
single organism metabolic processGO:00447102170.226
cellular macromolecule biosynthetic processGO:00346452240.220
cellular protein metabolic processGO:00442671290.216
Human Fly
modification dependent macromolecule catabolic processGO:004363230.212
Human Fly
cellular biosynthetic processGO:00442492860.201
mitotic cell cycleGO:0000278640.199
nucleoside monophosphate catabolic processGO:000912540.194
nuclear divisionGO:0000280230.159
meiotic nuclear divisionGO:000712640.158
regulation of chromosome segregationGO:005198310.149
regulation of biosynthetic processGO:00098892500.148
establishment of localizationGO:00512342440.146
single organism organelle organizationGO:19025891990.140
negative regulation of protein processingGO:0010955100.139
multicellular organism growthGO:003526440.138
pole plasm assemblyGO:000731540.135
response to topologically incorrect proteinGO:003596620.135
purine ribonucleoside monophosphate catabolic processGO:000916940.133
regulation of cellular metabolic processGO:00313233200.129
Human
cellular component assemblyGO:00226071700.127
negative regulation of mitosisGO:004583930.125
lipid storageGO:001991510.120
negative regulation of biological processGO:00485193040.119
locomotionGO:00400113130.118
Worm
organelle organizationGO:00069962270.111
macromolecular complex subunit organizationGO:0043933740.111
Fly
mitotic cell cycle processGO:1903047480.110
fertilizationGO:000956630.109
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.108
Human
single fertilizationGO:000733830.107
cell cycle processGO:0022402530.106
aromatic compound biosynthetic processGO:00194382170.105
atp catabolic processGO:000620040.105
negative regulation of nuclear divisionGO:005178430.103
protein metabolic processGO:00195381830.101
Human Fly
small molecule metabolic processGO:0044281770.099
macromolecule biosynthetic processGO:00090592270.098
negative regulation of cellular metabolic processGO:0031324770.098
negative regulation of macromolecule metabolic processGO:0010605760.095
chromosome organizationGO:0051276310.093
cell cycleGO:0007049930.092
embryo development ending in birth or egg hatchingGO:00097922710.089
positive regulation of catabolic processGO:000989640.088
Human
reproductionGO:0000003400.086
Worm
regulation of cellular protein metabolic processGO:0032268520.085
Human
regulation of synapse assemblyGO:005196330.083
response to stressGO:00069502630.083
cellular nitrogen compound metabolic processGO:00346412900.081
regulation of multicellular organismal processGO:00512392770.081
single organism localizationGO:19025782250.080
protein modification by small protein removalGO:007064610.080
Human Fly
organic substance biosynthetic processGO:19015762890.078
regulation of biological qualityGO:00650082630.078
negative regulation of metabolic processGO:0009892860.077
regulation of cellular biosynthetic processGO:00313262450.077
regulation of protein modification by small protein conjugation or removalGO:190332030.076
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.076
double strand break repairGO:000630230.076
microtubule cytoskeleton organization involved in mitosisGO:190285010.076
regulation of multicellular organism growthGO:004001440.074
regulation of synaptic growth at neuromuscular junctionGO:000858210.073
macromolecular complex disassemblyGO:003298410.072
Fly
cellular macromolecular complex assemblyGO:0034622240.071
cellular component disassemblyGO:002241110.071
Fly
mitotic sister chromatid segregationGO:000007060.071
regulation of synapse organizationGO:005080730.070
regulation of protein maturationGO:1903317100.067
cellular ketone metabolic processGO:0042180110.067
autophagyGO:000691440.067
cytokinesisGO:000091030.066
purine nucleoside monophosphate catabolic processGO:000912840.066
cellular protein modification processGO:00064641000.066
Human Fly
biosynthetic processGO:00090582940.065
negative regulation of cellular processGO:00485232830.065
regulation of cell cycleGO:0051726520.062
organic substance catabolic processGO:1901575280.061
Human Fly
regulation of developmental processGO:00507932470.061
positive regulation of dna templated transcription elongationGO:003278610.061
cellular catabolic processGO:0044248270.061
Human Fly
negative regulation of catabolic processGO:000989530.060
protein modification processGO:00362111000.059
Human Fly
synaptic growth at neuromuscular junctionGO:005112420.059
regulation of macromolecule biosynthetic processGO:00105562250.059
regulation of protein ubiquitinationGO:003139630.059
regulation of transcription from rna polymerase ii promoterGO:00063571140.058
negative regulation of proteolysisGO:0045861100.058
purine ribonucleotide metabolic processGO:0009150270.057
cytoskeleton organizationGO:0007010960.056
response to chemicalGO:00422213200.056
transportGO:00068102200.055
hatchingGO:003518840.053
regulation of meiotic cell cycleGO:005144510.053
covalent chromatin modificationGO:0016569200.052
regulation of cellular macromolecule biosynthetic processGO:20001122220.052
regulation of protein metabolic processGO:0051246560.052
Human
regulation of cellular ketone metabolic processGO:001056570.051
cell projection morphogenesisGO:00488582440.050
Fly
oocyte anterior posterior axis specificationGO:000731440.050
organic cyclic compound metabolic processGO:19013603010.049
protein acylationGO:004354330.048
negative regulation of cellular catabolic processGO:003133030.048
centrosome organizationGO:005129710.048
g2 m transition of mitotic cell cycleGO:000008640.047
regulation of proteolysisGO:0030162240.047
Human
developmental growthGO:00485891660.046
cellular component biogenesisGO:00440851780.046
protein complex disassemblyGO:004324110.046
Fly
rna biosynthetic processGO:00327741810.046
negative regulation of gene expressionGO:0010629650.045
macromolecule localizationGO:0033036540.045
nitrogen compound metabolic processGO:00068073190.045
proteolysisGO:0006508380.044
Human Fly
spindle assemblyGO:005122520.044
heterocycle metabolic processGO:00464832900.044
single organism transportGO:00447652060.044
cell cycle g2 m phase transitionGO:004483940.044
regulation of nitrogen compound metabolic processGO:00511712510.044
negative regulation of chromosome organizationGO:200125110.043
protein n linked glycosylationGO:000648710.043
meiotic cell cycle processGO:190304630.043
protein polymerizationGO:005125840.042
regulation of multicellular organismal developmentGO:20000262230.042
regulation of protein processingGO:0070613100.042
regulation of intracellular protein transportGO:003315730.042
rna metabolic processGO:00160702190.042
negative regulation of synapse assemblyGO:005196420.042
dna templated transcription initiationGO:000635210.041
cell divisionGO:0051301200.041
cell migrationGO:00164772370.040
positive regulation of cellular component biogenesisGO:004408930.040
cell deathGO:00082191210.040
regulation of cell shapeGO:000836010.040
positive regulation of cellular catabolic processGO:003133130.039
Human
negative regulation of multicellular organismal processGO:0051241690.039
positive regulation of protein complex assemblyGO:003133420.039
cellular nitrogen compound biosynthetic processGO:00442712180.039
protein processingGO:0016485120.038
meiosis iGO:000712710.038
transcription from rna polymerase ii promoterGO:0006366800.038
programmed cell deathGO:00125011190.038
regulation of protein complex assemblyGO:004325430.038
negative regulation of protein metabolic processGO:0051248160.038
deathGO:00162651210.038
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.038
single organism reproductive processGO:0044702400.037
Worm
positive regulation of cellular amino acid metabolic processGO:004576400.037
cellular protein complex assemblyGO:0043623190.037
negative regulation of cellular protein metabolic processGO:0032269160.036
regulation of response to stimulusGO:00485832690.036
transcription dna templatedGO:00063511810.036
cellular macromolecule catabolic processGO:0044265120.036
Human Fly
gamete generationGO:0007276330.036
regulation of cellular component organizationGO:0051128860.036
nucleobase containing compound metabolic processGO:00061392740.035
microtubule organizing center organizationGO:003102310.035
growthGO:00400071740.034
single organism biosynthetic processGO:0044711710.034
catabolic processGO:0009056320.034
Human Fly
macromolecule modificationGO:00434121110.033
Human Fly
posttranscriptional regulation of gene expressionGO:0010608140.033
protein acetylationGO:000647320.033
negative regulation of protein maturationGO:1903318100.033
positive regulation of biological processGO:00485182530.033
Human
cell motilityGO:00488702440.032
nucleic acid templated transcriptionGO:00976591810.032
sensory organ developmentGO:00074233930.032
nucleocytoplasmic transportGO:000691340.032
apoptotic process involved in developmentGO:190274220.032
positive regulation of nitrogen compound metabolic processGO:0051173690.031
regenerationGO:0031099910.031
regulation of rna metabolic processGO:00512522240.031
protein stabilizationGO:005082120.031
negative regulation of catalytic activityGO:0043086210.031
organonitrogen compound metabolic processGO:1901564740.031
cellular component movementGO:00069283350.031
developmental programmed cell deathGO:001062340.030
determination of bilateral symmetryGO:00098552040.030
negative regulation of cellular biosynthetic processGO:0031327550.030
cellular response to stressGO:0033554620.029
sister chromatid segregationGO:000081960.029
regulation of gene expression epigeneticGO:0040029110.029
oxoacid metabolic processGO:0043436310.029
cellular localizationGO:0051641970.029
positive regulation of apoptotic signaling pathwayGO:200123510.029
microtubule based processGO:0007017600.028
positive regulation of transportGO:005105020.028
response to organic substanceGO:00100331530.028
regulation of nucleobase containing compound metabolic processGO:00192192500.027
embryonic organ morphogenesisGO:00485622740.027
multi organism processGO:00517041340.027
maternal determination of anterior posterior axis embryoGO:000835840.027
eye developmentGO:00016542770.027
pronuclear migrationGO:003504610.027
system processGO:00030081850.027
cell surface receptor signaling pathwayGO:00071663250.027
cellular aromatic compound metabolic processGO:00067252950.027
cellular response to starvationGO:000926710.027
regulation of nucleocytoplasmic transportGO:004682220.027
ribosome assemblyGO:004225510.027
regulation of cell divisionGO:0051302120.026
nucleotide metabolic processGO:0009117280.026
macromolecule catabolic processGO:0009057150.026
Human Fly
cytoplasm organizationGO:000702840.026
heterocycle catabolic processGO:0046700150.026
cell substrate junction assemblyGO:000704420.026
organic acid metabolic processGO:0006082310.026
protein complex subunit organizationGO:0071822460.026
Fly
regulation of cytoplasmic transportGO:190364940.026
embryonic organ developmentGO:00485683810.025
nucleobase containing compound biosynthetic processGO:00346542050.025
regulation of anatomical structure morphogenesisGO:00226031300.025
cellular response to external stimulusGO:007149620.025
protein maturationGO:0051604120.025
positive regulation of cytosolic calcium ion concentrationGO:000720440.025
cell morphogenesisGO:00009022890.025
Fly
nucleic acid metabolic processGO:00903042440.025
rna localizationGO:000640340.025
protein import into nucleusGO:000660630.024
regulation of transcription dna templatedGO:00063552130.024
positive regulation of biosynthetic processGO:0009891680.024
positive regulation of macromolecule biosynthetic processGO:0010557590.024
apoptotic processGO:00069151160.024
regulation of rna biosynthetic processGO:20011412130.024
establishment of protein localization to organelleGO:007259440.024
regulation of catalytic activityGO:0050790550.024
negative regulation of cytoplasmic transportGO:190365020.023
regulation of dna templated transcription elongationGO:003278430.023
specification of symmetryGO:00097992040.023
regulation of developmental growthGO:0048638380.023
regulation of bindingGO:005109830.023
purine containing compound metabolic processGO:0072521290.023
regulation of cellular amine metabolic processGO:003323800.023
carboxylic acid metabolic processGO:0019752220.023
positive regulation of macromolecule metabolic processGO:0010604930.023
Human
regulation of establishment of protein localizationGO:007020140.022
organic substance transportGO:0071702580.022
development of primary female sexual characteristicsGO:004654540.022
single organism nuclear importGO:190259330.022
regulation of i kappab kinase nf kappab signalingGO:004312240.022
internal peptidyl lysine acetylationGO:001839320.022
nuclear transportGO:005116940.022
centrosome cycleGO:000709810.021
meiotic spindle organizationGO:000021210.021
rna catabolic processGO:000640170.021
carbohydrate derivative metabolic processGO:1901135610.021
regulation of extrinsic apoptotic signaling pathwayGO:200123630.021
single organism intracellular transportGO:1902582250.021
macromolecular complex assemblyGO:0065003350.021
positive regulation of cellular processGO:00485222010.020
Human
internal protein amino acid acetylationGO:000647520.020
positive regulation of cellular carbohydrate metabolic processGO:001067610.020
regulation of cell communicationGO:00106462320.020
cellular response to dna damage stimulusGO:0006974240.020
camera type eye developmentGO:00430102220.020
phosphorus metabolic processGO:00067931090.020
regulation of protein transportGO:005122330.020
negative regulation of biosynthetic processGO:0009890550.020
immune system processGO:00023762410.020
mitotic recombinationGO:000631220.020
synaptic vesicle localizationGO:009747910.020
organic cyclic compound biosynthetic processGO:19013622230.020
meiotic chromosome segregationGO:004513230.020
chromatin modificationGO:0016568210.020
sister chromatid cohesionGO:000706220.020
central nervous system developmentGO:00074173870.019
transcription elongation from rna polymerase ii promoterGO:000636830.019
extrinsic apoptotic signaling pathwayGO:009719130.019
regulation of purine nucleotide catabolic processGO:003312120.019
sensory organ morphogenesisGO:00905962000.019
signal transductionGO:00071654550.019
negative regulation of nucleocytoplasmic transportGO:004682320.019
negative regulation of endopeptidase activityGO:0010951100.019
organelle assemblyGO:00709251100.019
peptidyl lysine acetylationGO:001839420.019
regulation of localizationGO:00328791040.019
mrna export from nucleusGO:000640610.018
cell morphogenesis involved in neuron differentiationGO:00486671630.018
regulation of peptidase activityGO:0052547230.018
protein importGO:001703830.018
gene silencing by rnaGO:003104740.018
cell projection organizationGO:00300302840.018
Fly
cell part morphogenesisGO:00329902460.018
Fly
establishment of localization in cellGO:0051649770.018
regulation of growthGO:0040008420.018
tissue regenerationGO:0042246740.018
regulation of protein targetingGO:190353320.018
regulation of translational initiationGO:000644610.018
positive regulation of cell activationGO:005086710.018
regulation of apoptotic processGO:0042981980.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
chromatin organizationGO:0006325220.017
cellular response to reactive oxygen speciesGO:003461420.017
dna templated transcription elongationGO:000635430.017
neurological system processGO:0050877620.017
cellular amine metabolic processGO:004410620.017
regulation of signal transductionGO:00099662250.017
chromosome segregationGO:0007059120.017
organism emergence from protective structureGO:007168440.017
apoptotic process involved in morphogenesisGO:006056120.017
cellular response to chemical stimulusGO:00708871570.017
reproductive processGO:0022414400.016
Worm
cellular carbohydrate metabolic processGO:004426240.016
regulation of cell activationGO:005086510.016
chemotaxisGO:00069351040.016
protein targeting to nucleusGO:004474430.016
mitotic cell cycle phase transitionGO:004477290.016
generation of neuronsGO:00486993850.016
Fly
response to hydrogen peroxideGO:004254230.016
regulation of signalingGO:00230512350.016
carbohydrate biosynthetic processGO:001605110.016
organelle localizationGO:0051640490.016
dna catabolic processGO:000630810.016
microtubule cytoskeleton organizationGO:0000226330.016
positive regulation of rna biosynthetic processGO:1902680570.016
brain developmentGO:00074202930.016
protein catabolic processGO:003016370.016
Human Fly
response to external stimulusGO:00096052640.016
cellular response to nutrient levelsGO:003166920.016
cellular response to extracellular stimulusGO:003166820.016
phosphate containing compound metabolic processGO:00067961080.015
positive regulation of cytoskeleton organizationGO:005149530.015
male meiosisGO:000714020.015
peptidyl amino acid modificationGO:0018193160.015
synaptic vesicle transportGO:004848910.015
response to temperature stimulusGO:0009266150.015
cell matrix adhesionGO:000716040.015
sexual reproductionGO:0019953360.015
lateral inhibitionGO:004633110.015
positive regulation of cellular amine metabolic processGO:003324000.015
taxisGO:00423301090.015
regulation of stem cell proliferationGO:007209120.015
protein glycosylationGO:000648690.015
response to drugGO:004249330.015
regulation of gtpase activityGO:004308720.015
response to cadmium ionGO:0046686140.014
negative regulation of protein phosphorylationGO:000193340.014
cellular amino acid metabolic processGO:000652070.014
rrna catabolic processGO:001607510.014
defense responseGO:0006952470.014
mrna transportGO:005102820.014
locomotor rhythmGO:004547530.014
translational initiationGO:000641330.014
macroautophagyGO:001623610.014
regionalizationGO:00030022740.014
regulation of cellular carbohydrate metabolic processGO:001067540.014
regulation of endopeptidase activityGO:0052548230.014
purine nucleotide metabolic processGO:0006163270.014
regulation of carbohydrate metabolic processGO:000610940.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
negative regulation of peptidase activityGO:0010466100.014
positive regulation of nucleic acid templated transcriptionGO:1903508570.013
phagocytosisGO:000690930.013
nucleobase containing small molecule metabolic processGO:0055086320.013
amine metabolic processGO:000930820.013
regulation of programmed cell deathGO:00430671010.013
exocytosisGO:000688710.013
ribose phosphate metabolic processGO:0019693270.013
mitochondrion organizationGO:000700540.013
i kappab kinase nf kappab signalingGO:000724940.013
mitotic dna integrity checkpointGO:004477440.013
regulation of carbohydrate biosynthetic processGO:004325510.013
3 utr mediated mrna stabilizationGO:007093530.013
regulation of mitosisGO:000708890.013
positive regulation of chromatin modificationGO:190331010.013
regulation of organelle organizationGO:0033043290.013
ncrna catabolic processGO:003466110.013
negative regulation of intracellular transportGO:003238730.013
nuclear migrationGO:000709730.013
multicellular organism reproductionGO:0032504350.013
regulation of microtubule cytoskeleton organizationGO:007050730.013
positive regulation of cellular biosynthetic processGO:0031328680.012
negative regulation of stem cell differentiationGO:200073720.012
signal transduction in absence of ligandGO:003803410.012
organic cyclic compound catabolic processGO:1901361150.012
protein secretionGO:000930610.012
carbohydrate derivative biosynthetic processGO:1901137430.012
interspecies interaction between organismsGO:004441940.012
localization of cellGO:00516742440.012
regulation of dna replicationGO:000627530.012
sympathetic nervous system developmentGO:004848530.012
nuclear importGO:005117030.012
protein modification by small protein conjugation or removalGO:0070647140.012
Human Fly
negative regulation of cell deathGO:0060548600.012
hematopoietic or lymphoid organ developmentGO:00485341910.012
positive regulation of rna metabolic processGO:0051254590.012
response to woundingGO:00096111160.012
positive regulation of transcription dna templatedGO:0045893570.012
protein k63 linked ubiquitinationGO:007053420.012
intracellular mrna localizationGO:000829810.012
intracellular signal transductionGO:0035556850.012
regulation of cellular amino acid metabolic processGO:000652100.012
single organism cellular localizationGO:1902580460.012
purine ribonucleoside monophosphate metabolic processGO:000916750.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
regulation of mrna processingGO:005068430.011
mitotic g2 dna damage checkpointGO:000709530.011
regulation of nervous system developmentGO:0051960900.011
ribonucleotide metabolic processGO:0009259270.011
dna biosynthetic processGO:007189730.011
histone h3 k4 methylationGO:005156820.011
negative regulation of programmed cell deathGO:0043069580.011
transmembrane transportGO:00550851200.011
regulation of inflammatory responseGO:005072720.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
regulation of cell deathGO:00109411030.011
nucleic acid transportGO:005065720.011
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.011
segmentationGO:0035282970.011
negative regulation of hydrolase activityGO:0051346100.011
establishment of rna localizationGO:005123630.011
female gonad developmentGO:000858540.011
positive regulation of translationGO:004572710.011
nucleobase containing compound transportGO:001593120.011
cell substrate adhesionGO:003158940.011
regulation of receptor mediated endocytosisGO:004825940.011
macromolecule deacylationGO:009873230.011
protein complex assemblyGO:0006461300.011
positive regulation of chromosome organizationGO:200125210.011
behaviorGO:0007610740.011
regulation of locomotionGO:0040012550.011
neuron projection morphogenesisGO:00488121610.011
Fly
positive regulation of mesenchymal cell proliferationGO:000205310.011
gene silencingGO:001645840.011
heart field specificationGO:000312810.011
intracellular transportGO:0046907320.011
translationGO:000641250.010
protein deacetylationGO:000647630.010
histone deacetylationGO:001657520.010
post embryonic developmentGO:000979170.010
histone modificationGO:0016570200.010
multicellular organismal signalingGO:0035637220.010
negative regulation of defense responseGO:003134820.010
vesicle mediated transportGO:0016192220.010
nucleobase containing compound catabolic processGO:0034655150.010
positive regulation of cellular metabolic processGO:0031325940.010
Human
regulation of nucleoside metabolic processGO:000911820.010
protein complex biogenesisGO:0070271300.010
establishment of endothelial barrierGO:006102830.010
fin regenerationGO:0031101510.010
positive regulation of nucleobase containing compound metabolic processGO:0045935690.010
cellular response to interferon gammaGO:007134610.010
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.010
negative regulation of intracellular protein transportGO:009031730.010
regulation of response to external stimulusGO:0032101310.010

usp5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.088
disease of cellular proliferationDOID:1456600.037
cancerDOID:16200.037
organ system cancerDOID:005068600.037
nervous system diseaseDOID:86300.028
neurodegenerative diseaseDOID:128900.013
amyotrophic lateral sclerosisDOID:33200.013
central nervous system diseaseDOID:33100.013
motor neuron diseaseDOID:23100.013
musculoskeletal system diseaseDOID:1700.011
neuromuscular diseaseDOID:44000.011
charcot marie tooth disease type 2DOID:005053900.011
charcot marie tooth diseaseDOID:1059500.011
neuropathyDOID:87000.011