Danio rerio

37 known processes

fras1

Fraser syndrome 1

(Aliases: wu:fc10b09,si:ch211-191a6.5,pif,id:ibd5080)

fras1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
axonal defasciculationGO:000741420.991
embryonic organ developmentGO:00485683810.982
chordate embryonic developmentGO:00430092710.960
fin morphogenesisGO:0033334530.957
appendage morphogenesisGO:0035107560.956
fin developmentGO:0033333770.950
embryo development ending in birth or egg hatchingGO:00097922710.950
positive regulation of biological processGO:00485182530.943
signal transductionGO:00071654550.942
regulation of signalingGO:00230512350.939
medial fin morphogenesisGO:0035141140.935
medial fin developmentGO:0033338160.930
cell motilityGO:00488702440.896
dorsal ventral pattern formationGO:00099531250.875
embryonic organ morphogenesisGO:00485622740.870
skin developmentGO:0043588540.848
Mouse
embryonic viscerocranium morphogenesisGO:0048703520.831
embryonic appendage morphogenesisGO:0035113300.792
Mouse
appendage developmentGO:0048736800.775
heart developmentGO:00075073130.774
skeletal system morphogenesisGO:00487051020.747
pectoral fin developmentGO:0033339500.746
neuron projection developmentGO:00311751800.710
regulation of response to stimulusGO:00485832690.667
determination of dorsal ventral asymmetryGO:0048262340.653
transcription dna templatedGO:00063511810.645
regulation of multicellular organismal processGO:00512392770.642
localization of cellGO:00516742440.628
hemopoiesisGO:00300971830.625
larval developmentGO:000216420.611
wound healingGO:0042060900.609
positive regulation of cellular processGO:00485222010.607
locomotionGO:00400113130.538
neuron developmentGO:00486662620.524
cellular component movementGO:00069283350.523
digestive system developmentGO:00551232890.519
embryonic skeletal system morphogenesisGO:0048704930.516
gastrulationGO:00073692080.511
formation of primary germ layerGO:0001704620.495
hematopoietic or lymphoid organ developmentGO:00485341910.489
cartilage developmentGO:0051216960.487
negative regulation of response to stimulusGO:00485851040.462
cell migrationGO:00164772370.434
cell surface receptor signaling pathwayGO:00071663250.434
cellular component morphogenesisGO:00329893360.433
regulation of biosynthetic processGO:00098892500.417
regulation of cell communicationGO:00106462320.413
regulation of macromolecule metabolic processGO:00602553170.410
positive regulation of cellular metabolic processGO:0031325940.408
regulation of metabolic processGO:00192223590.399
cell morphogenesis involved in neuron differentiationGO:00486671630.397
meiotic cell cycle processGO:190304630.396
pectoral fin morphogenesisGO:0035138290.393
immune system developmentGO:00025201910.392
negative regulation of cellular processGO:00485232830.388
regenerationGO:0031099910.385
enzyme linked receptor protein signaling pathwayGO:00071671060.379
digestive tract developmentGO:00485652650.373
nucleic acid metabolic processGO:00903042440.372
biosynthetic processGO:00090582940.369
cell proliferationGO:0008283800.366
meiotic nuclear divisionGO:000712640.364
epithelial cell developmentGO:0002064420.357
regulation of cellular biosynthetic processGO:00313262450.357
regulation of signal transductionGO:00099662250.355
regulation of cellular component movementGO:0051270550.343
specification of symmetryGO:00097992040.336
regulation of nitrogen compound metabolic processGO:00511712510.328
positive regulation of locomotionGO:0040017140.326
response to chemicalGO:00422213200.317
embryonic pectoral fin morphogenesisGO:0035118240.305
embryonic medial fin morphogenesisGO:003512260.302
response to external stimulusGO:00096052640.292
macromolecular complex subunit organizationGO:0043933740.284
regulation of gene expressionGO:00104682650.282
embryonic limb morphogenesisGO:003032620.277
Mouse
cellular response to chemical stimulusGO:00708871570.275
skeletal system developmentGO:00015011810.274
regulation of biological qualityGO:00650082630.272
regulation of locomotionGO:0040012550.262
cellular protein catabolic processGO:004425740.252
inner ear developmentGO:00488391260.242
axon developmentGO:00615641660.239
tube morphogenesisGO:00352393490.237
cellular response to organic substanceGO:00713101050.232
thyroid gland developmentGO:0030878120.231
cell projection organizationGO:00300302840.231
heterocycle metabolic processGO:00464832900.225
locus ceruleus developmentGO:002170330.222
cellular biosynthetic processGO:00442492860.221
immune system processGO:00023762410.220
mesoderm developmentGO:0007498880.211
regulation of developmental processGO:00507932470.201
sensory organ morphogenesisGO:00905962000.201
regionalizationGO:00030022740.199
organelle organizationGO:00069962270.199
negative regulation of signal transductionGO:0009968940.196
transcription from rna polymerase ii promoterGO:0006366800.194
positive regulation of response to stimulusGO:0048584800.191
muscle structure developmentGO:00610611960.190
ectodermal placode developmentGO:0071696370.187
nucleic acid templated transcriptionGO:00976591810.186
ear developmentGO:00435831270.184
nucleobase containing compound biosynthetic processGO:00346542050.180
negative regulation of multicellular organismal processGO:0051241690.179
heart morphogenesisGO:00030071560.179
regulation of cell adhesionGO:0030155150.175
cell part morphogenesisGO:00329902460.171
positive regulation of catabolic processGO:000989640.169
positive regulation of metabolic processGO:00098931080.166
organic cyclic compound biosynthetic processGO:19013622230.162
semicircular canal developmentGO:0060872240.162
protein complex subunit organizationGO:0071822460.162
hatchingGO:003518840.161
deathGO:00162651210.158
cell morphogenesisGO:00009022890.153
regulation of multicellular organismal developmentGO:20000262230.152
regulation of cell motilityGO:2000145460.150
intracellular signal transductionGO:0035556850.148
taxisGO:00423301090.145
cell morphogenesis involved in differentiationGO:00009041950.144
regulation of rna metabolic processGO:00512522240.144
generation of neuronsGO:00486993850.139
regulation of cellular component organizationGO:0051128860.139
single organism biosynthetic processGO:0044711710.137
regulation of transcription dna templatedGO:00063552130.137
stem cell proliferationGO:007208940.136
response to transforming growth factor betaGO:007155970.135
regulation of protein catabolic processGO:004217610.133
single organism localizationGO:19025782250.133
cell substrate adhesionGO:003158940.132
palate developmentGO:006002180.129
Mouse
regulation of anatomical structure morphogenesisGO:00226031300.128
cellular aromatic compound metabolic processGO:00067252950.127
single organism organelle organizationGO:19025891990.127
cell deathGO:00082191210.122
nucleobase containing compound metabolic processGO:00061392740.121
regulation of cell proliferationGO:0042127370.121
actin filament organizationGO:0007015150.121
extracellular matrix organizationGO:0030198270.121
epithelial cell differentiationGO:00308551160.119
blood vessel morphogenesisGO:00485142160.117
establishment of localizationGO:00512342440.116
Mouse
regulation of nucleobase containing compound metabolic processGO:00192192500.116
cellular nitrogen compound metabolic processGO:00346412900.116
central nervous system developmentGO:00074173870.116
angiogenesisGO:00015251580.116
regulation of wnt signaling pathwayGO:0030111530.113
gamete generationGO:0007276330.111
neuron differentiationGO:00301823530.111
positive regulation of multicellular organismal processGO:0051240520.110
ectodermal placode morphogenesisGO:0071697320.109
organic cyclic compound metabolic processGO:19013603010.109
rhombomere 5 developmentGO:002157140.109
organism emergence from protective structureGO:007168440.107
regulation of programmed cell deathGO:00430671010.104
response to stressGO:00069502630.101
caudal fin developmentGO:003333690.099
mesenchymal cell proliferationGO:001046310.098
positive regulation of programmed cell deathGO:0043068290.098
single organism reproductive processGO:0044702400.098
aromatic compound biosynthetic processGO:00194382170.096
growthGO:00400071740.095
tissue regenerationGO:0042246740.094
cranial suture morphogenesisGO:006036310.093
epidermis developmentGO:0008544480.090
cytoskeleton organizationGO:0007010960.090
embryonic neurocranium morphogenesisGO:0048702150.089
hindbrain formationGO:002157630.089
regulation of synapse assemblyGO:005196330.087
negative regulation of biological processGO:00485193040.087
regulation of nervous system developmentGO:0051960900.084
regulation of cell migrationGO:0030334400.084
blood vessel developmentGO:00015682460.083
osteoclast developmentGO:003603510.083
caudal fin morphogenesisGO:003514370.082
cell proliferation involved in heart morphogenesisGO:006132320.081
mesoderm morphogenesisGO:0048332510.081
positive regulation of cell proliferationGO:0008284150.079
rhombomere developmentGO:0021546190.078
regulation of localizationGO:00328791040.078
vasculature developmentGO:00019442780.077
neuron projection morphogenesisGO:00488121610.077
regulation of cell proliferation involved in heart morphogenesisGO:200013620.076
single organism transportGO:00447652060.075
paraxial mesoderm developmentGO:004833980.074
regulation of bindingGO:005109830.074
transportGO:00068102200.073
Mouse
regulation of apoptotic processGO:0042981980.072
taste bud formationGO:006119530.071
cellular response to growth factor stimulusGO:0071363390.071
organic substance biosynthetic processGO:19015762890.071
connective tissue developmentGO:0061448990.070
striated muscle cell differentiationGO:00511461290.070
developmental growth involved in morphogenesisGO:0060560860.070
protein localization to nucleusGO:003450430.070
developmental growthGO:00485891660.070
synaptic growth at neuromuscular junctionGO:005112420.069
otolith developmentGO:0048840320.067
positive regulation of cell communicationGO:0010647560.067
cellular macromolecule biosynthetic processGO:00346452240.066
proteolysis involved in cellular protein catabolic processGO:005160330.066
embryonic camera type eye developmentGO:0031076290.065
macromolecule localizationGO:0033036540.065
Mouse
regulation of epithelial cell proliferationGO:005067830.065
nitrogen compound metabolic processGO:00068073190.065
positive regulation of cell adhesionGO:004578510.065
chondrocyte developmentGO:000206340.064
head developmentGO:00603223030.064
cell matrix adhesionGO:000716040.063
cartilage condensationGO:000150230.062
transmembrane transportGO:00550851200.062
hard palate developmentGO:006002240.062
eye morphogenesisGO:00485921440.061
actin cytoskeleton organizationGO:0030036630.060
microtubule based processGO:0007017600.060
regulation of vasculature developmentGO:1901342330.060
single organism metabolic processGO:00447102170.057
morphogenesis of an epitheliumGO:00020093330.057
Mouse
vestibular receptor cell developmentGO:006011830.057
hindbrain developmentGO:0030902910.056
anterior posterior pattern specificationGO:00099521520.056
small molecule metabolic processGO:0044281770.055
otic placode formationGO:0043049230.054
modification dependent protein catabolic processGO:001994130.054
branching morphogenesis of an epithelial tubeGO:0048754150.054
multicellular organismal reproductive processGO:0048609350.051
regulation of tube sizeGO:003515020.051
odontogenesisGO:004247690.050
determination of bilateral symmetryGO:00098552040.049
positive regulation of transportGO:005105020.049
exocrine system developmentGO:0035272280.048
meiotic chromosome segregationGO:004513230.048
gland developmentGO:00487321430.048
cellular macromolecule metabolic processGO:00442603910.048
regulation of intracellular signal transductionGO:1902531570.047
regulation of cytoskeleton organizationGO:0051493110.047
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.046
regulation of transmembrane transportGO:0034762180.046
circulatory system processGO:0003013870.046
apoptotic processGO:00069151160.046
embryonic cranial skeleton morphogenesisGO:0048701900.046
lens fiber cell developmentGO:007030730.045
odontogenesis of dentin containing toothGO:004247510.045
proteasomal protein catabolic processGO:001049820.045
morphogenesis of an epithelial sheetGO:0002011490.045
positive regulation of skeletal muscle tissue developmentGO:004864310.045
positive regulation of developmental processGO:0051094500.045
ameboidal type cell migrationGO:00016671430.044
positive regulation of map kinase activityGO:004340630.044
trigeminal nerve developmentGO:002155930.044
positive regulation of cell motilityGO:2000147110.044
organ formationGO:0048645170.044
regulation of extrinsic apoptotic signaling pathwayGO:200123630.044
phosphorus metabolic processGO:00067931090.044
developmental process involved in reproductionGO:0003006270.044
somite developmentGO:0061053960.044
macromolecule biosynthetic processGO:00090592270.044
cellular component biogenesisGO:00440851780.043
regulation of cell differentiationGO:00455951420.043
rhombomere 6 developmentGO:002157240.043
positive regulation of cellular catabolic processGO:003133130.043
negative regulation of embryonic developmentGO:0045992110.043
positive regulation of cellular biosynthetic processGO:0031328680.043
negative regulation of signalingGO:0023057960.042
midbrain developmentGO:0030901280.042
cellular component assemblyGO:00226071700.041
muscle contractionGO:0006936180.041
b cell activationGO:004211320.041
nephron tubule morphogenesisGO:007207810.041
ion transportGO:00068111140.041
regulation of nucleic acid templated transcriptionGO:19035062130.040
positive regulation of macromolecule metabolic processGO:0010604930.040
mesenchyme developmentGO:00604851270.040
embryonic skeletal system developmentGO:0048706970.040
segmentationGO:0035282970.040
neural tube patterningGO:0021532330.039
regulation of rna biosynthetic processGO:20011412130.039
brain developmentGO:00074202930.039
regulation of cellular protein catabolic processGO:190336210.039
intestinal epithelial cell differentiationGO:006057530.038
protein complex biogenesisGO:0070271300.038
negative regulation of striated muscle tissue developmentGO:004584320.038
fin regenerationGO:0031101510.038
ossificationGO:0001503230.038
cell migration involved in gastrulationGO:0042074790.038
positive regulation of signalingGO:0023056560.037
axonogenesisGO:00074091520.037
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.037
basement membrane organizationGO:007171150.037
cellular process involved in reproduction in multicellular organismGO:0022412280.037
regulation of nucleocytoplasmic transportGO:004682220.037
positive regulation of apoptotic signaling pathwayGO:200123510.036
cognitionGO:005089010.036
septum transversum developmentGO:000334340.036
positive regulation of apoptotic processGO:0043065290.035
cation transmembrane transportGO:0098655650.035
inner ear morphogenesisGO:0042472630.035
single organism cellular localizationGO:1902580460.034
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.034
negative regulation of developmental processGO:0051093650.034
neutrophil chemotaxisGO:0030593100.034
protein metabolic processGO:00195381830.033
regulation of angiogenesisGO:0045765260.033
protein importGO:001703830.033
negative regulation of protein kinase activityGO:000646940.033
positive regulation of nervous system developmentGO:0051962250.032
retina morphogenesis in camera type eyeGO:0060042790.032
ras protein signal transductionGO:000726570.032
cilium morphogenesisGO:0060271850.032
establishment of localization in cellGO:0051649770.032
regulation of primary metabolic processGO:00800903110.032
pons developmentGO:0021548110.032
regulation of cellular macromolecule biosynthetic processGO:20001122220.032
vestibular receptor cell differentiationGO:006011430.032
heterocycle biosynthetic processGO:00181302150.031
negative regulation of macromolecule metabolic processGO:0010605760.031
atrial ventricular junction remodelingGO:000329420.031
cellular response to external stimulusGO:007149620.031
single organism nuclear importGO:190259330.031
cell cycle processGO:0022402530.031
rna biosynthetic processGO:00327741810.031
response to growth factorGO:0070848390.031
cellular response to stressGO:0033554620.031
muscle cell differentiationGO:00426921390.030
oxoacid metabolic processGO:0043436310.030
negative regulation of axon extension involved in axon guidanceGO:004884310.030
negative regulation of calcium dependent cell cell adhesionGO:004658810.030
regulation of bone remodelingGO:004685020.030
lipid biosynthetic processGO:0008610220.030
negative regulation of cell adhesionGO:000716260.029
system processGO:00030081850.029
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.029
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.029
mononuclear cell proliferationGO:003294310.029
regulation of blood coagulationGO:003019310.029
rna metabolic processGO:00160702190.029
cardiac ventricle formationGO:000321110.028
cell adhesionGO:0007155400.028
regulation of cellular metabolic processGO:00313233200.027
protein polymerizationGO:005125840.027
camera type eye morphogenesisGO:00485931080.027
semicircular canal morphogenesisGO:0048752180.027
embryonic heart tube developmentGO:00350501330.027
germ line stem cell maintenanceGO:003071820.027
negative regulation of signal transduction in absence of ligandGO:190109910.027
reproductionGO:0000003400.027
nephron epithelium morphogenesisGO:007208810.026
regulation of macromolecule biosynthetic processGO:00105562250.026
response to woundingGO:00096111160.026
signal transduction by phosphorylationGO:0023014180.026
negative regulation of metabolic processGO:0009892860.026
biological adhesionGO:0022610400.025
positive regulation of cell migrationGO:0030335110.025
positive regulation of leukocyte migrationGO:000268720.025
positive regulation of stem cell proliferationGO:200064810.025
determination of left right symmetryGO:00073681790.025
single organism cell adhesionGO:0098602290.025
regulation of heart contractionGO:0008016320.025
ubiquitin dependent protein catabolic processGO:000651130.025
cerebellum formationGO:002158820.024
muscle cell fate determinationGO:000752110.024
regulation of establishment of protein localizationGO:007020140.024
cranial nerve developmentGO:0021545420.024
sensory system developmentGO:0048880760.024
embryonic caudal fin morphogenesisGO:003512430.024
sprouting angiogenesisGO:0002040530.024
axon extension involved in axon guidanceGO:0048846100.024
response to topologically incorrect proteinGO:003596620.024
cell cycle g1 s phase transitionGO:004484310.024
positive regulation of mesenchymal cell proliferationGO:000205310.024
cardiac muscle cell differentiationGO:0055007300.023
cellular response to endogenous stimulusGO:0071495680.023
cellular protein complex assemblyGO:0043623190.023
endodermal cell differentiationGO:0035987190.023
positive regulation of canonical wnt signaling pathwayGO:009026340.023
membrane repolarizationGO:008600920.022
modification dependent macromolecule catabolic processGO:004363230.022
taste bud developmentGO:006119330.022
positive regulation of signal transductionGO:0009967560.022
cellular localizationGO:0051641970.022
bone remodelingGO:004684920.022
organonitrogen compound metabolic processGO:1901564740.022
granulocyte chemotaxisGO:0071621110.022
cellular catabolic processGO:0044248270.021
heart processGO:0003015710.021
inorganic ion transmembrane transportGO:0098660570.021
axon guidanceGO:0007411860.021
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.021
multicellular organism growthGO:003526440.021
beta amyloid formationGO:003420510.020
negative regulation of muscle tissue developmentGO:190186220.020
regulation of cell shapeGO:000836010.020
oogenesisGO:0048477140.020
regulation of molecular functionGO:0065009700.020
protein targeting to nucleusGO:004474430.020
regulation of cell cycleGO:0051726520.020
carboxylic acid metabolic processGO:0019752220.020
cell projection assemblyGO:0030031640.020
viral processGO:001603210.020
specification of organ identityGO:001009220.020
germ cell developmentGO:0007281220.020
response to oxygen containing compoundGO:1901700550.020
ear morphogenesisGO:0042471640.019
cellular nitrogen compound biosynthetic processGO:00442712180.019
actin filament based processGO:0030029640.019
mitotic cell cycleGO:0000278640.019
regulation of cell cell adhesionGO:0022407130.019
positive regulation of epithelial cell migrationGO:001063420.019
neuron fate specificationGO:0048665200.019
organophosphate metabolic processGO:0019637370.019
regulation of cytokine productionGO:000181730.019
negative regulation of cytoplasmic transportGO:190365020.019
regulation of protein complex assemblyGO:004325430.018
apoptotic signaling pathwayGO:0097190230.018
face developmentGO:006032480.018
gene expressionGO:00104672520.018
renal system developmentGO:0072001940.018
Mouse
venous endothelial cell migration involved in lymph vessel developmentGO:006085540.018
phosphorylationGO:0016310690.018
rho protein signal transductionGO:000726650.017
protein localizationGO:0008104400.017
Mouse
ectodermal placode formationGO:0060788260.017
phosphate containing compound metabolic processGO:00067961080.017
kidney developmentGO:0001822920.017
Mouse
alcohol biosynthetic processGO:004616520.017
axis specificationGO:0009798430.017
regulation of establishment of protein localization to plasma membraneGO:009000310.017
meiosis iGO:000712710.017
erk1 and erk2 cascadeGO:007037140.017
epidermal cell differentiationGO:0009913360.017
regulation of mitotic cell cycle phase transitionGO:190199080.017
negative regulation of programmed cell deathGO:0043069580.017
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100100.017
mesoderm formationGO:0001707430.017
otic vesicle developmentGO:0071599420.017
regulation of axon guidanceGO:190266780.017
stem cell maintenanceGO:001982740.016
blood circulationGO:0008015870.016
taste bud morphogenesisGO:006119430.016
negative regulation of defense responseGO:003134820.016
neuron projection guidanceGO:0097485860.016
protein localization to plasma membraneGO:007265910.016
microglia differentiationGO:001400410.016
regulation of cell activationGO:005086510.016
nephron developmentGO:0072006310.016
metal ion transportGO:0030001580.016
regulation of blood vessel sizeGO:005088020.016
cartilage morphogenesisGO:0060536130.016
chemotaxisGO:00069351040.016
pharyngeal muscle developmentGO:004328240.016
homeostatic processGO:00425921420.016
renal tubule morphogenesisGO:006133310.016
negative regulation of axon guidanceGO:190266810.016
water homeostasisGO:003010440.016
myeloid cell developmentGO:0061515320.016
regulation of cell developmentGO:00602841000.016
negative regulation of intracellular signal transductionGO:1902532220.016
beta amyloid metabolic processGO:005043510.016
small gtpase mediated signal transductionGO:000726480.015
protein catabolic processGO:003016370.015
cellular lipid metabolic processGO:0044255360.015
lymphocyte proliferationGO:004665110.015
somitogenesisGO:0001756870.015
negative regulation of cardiac muscle tissue developmentGO:005502610.015
mesodermal cell differentiationGO:0048333210.015
intracellular transportGO:0046907320.015
heart joggingGO:0003146400.015
proximal distal pattern formationGO:000995410.015
protein import into nucleusGO:000660630.015
proepicardium developmentGO:000334240.015
regulation of cellular response to growth factor stimulusGO:0090287350.015
reproductive processGO:0022414400.014
positive regulation of gene expressionGO:0010628710.014
positive regulation of muscle cell differentiationGO:005114910.014

fras1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.280
endocrine gland cancerDOID:17000.138
cancerDOID:16200.138
disease of cellular proliferationDOID:1456600.138
organ system cancerDOID:005068600.138
bone development diseaseDOID:008000600.082
bone diseaseDOID:008000100.082
osteochondrodysplasiaDOID:225600.082
musculoskeletal system diseaseDOID:1700.082
connective tissue diseaseDOID:6500.082
nervous system diseaseDOID:86300.081
retinal diseaseDOID:567900.052
sensory system diseaseDOID:005015500.052
retinal degenerationDOID:846600.052
eye and adnexa diseaseDOID:149200.052
eye diseaseDOID:561400.052
thyroid cancerDOID:178100.028
thyroid carcinomaDOID:396300.028
disease of metabolismDOID:001466700.027
inherited metabolic disorderDOID:65500.027
lysosomal storage diseaseDOID:321100.027