Danio rerio

13 known processes

rpa1

replication protein A1

(Aliases: zgc:77092,zgc:55337,wu:fi14b08)

rpa1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.780
cellular macromolecule biosynthetic processGO:00346452240.592
Human Yeast
embryo development ending in birth or egg hatchingGO:00097922710.523
Mouse Worm
cellular component biogenesisGO:00440851780.458
regulation of cellular macromolecule biosynthetic processGO:20001122220.455
cellular aromatic compound metabolic processGO:00067252950.435
Human Yeast Mouse
negative regulation of biological processGO:00485193040.382
regulation of cellular metabolic processGO:00313233200.366
regulation of metabolic processGO:00192223590.362
Worm
regulation of macromolecule metabolic processGO:00602553170.352
rna metabolic processGO:00160702190.341
cellular biosynthetic processGO:00442492860.332
Human Yeast
nucleic acid metabolic processGO:00903042440.327
Human Yeast Mouse
cellular nitrogen compound metabolic processGO:00346412900.318
Human Yeast Mouse
organic cyclic compound metabolic processGO:19013603010.318
Human Yeast Mouse
regulation of macromolecule biosynthetic processGO:00105562250.318
regulation of transcription dna templatedGO:00063552130.300
heterocycle metabolic processGO:00464832900.298
Human Yeast Mouse
organic substance biosynthetic processGO:19015762890.293
Human Yeast
locomotionGO:00400113130.278
heterocycle biosynthetic processGO:00181302150.265
transcription dna templatedGO:00063511810.256
regulation of gene expressionGO:00104682650.252
purine nucleoside monophosphate catabolic processGO:000912840.251
agingGO:000756820.244
nucleobase containing compound biosynthetic processGO:00346542050.238
single organism metabolic processGO:00447102170.232
Human Yeast Mouse
macromolecular complex assemblyGO:0065003350.227
cellular nitrogen compound biosynthetic processGO:00442712180.219
regulation of biosynthetic processGO:00098892500.219
single organism localizationGO:19025782250.214
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.214
cellular component assemblyGO:00226071700.213
protein acetylationGO:000647320.199
macromolecule biosynthetic processGO:00090592270.193
Human Yeast
positive regulation of biological processGO:00485182530.187
Mouse Worm
response to stressGO:00069502630.184
Human Yeast Mouse
chromosome organizationGO:0051276310.181
Human Yeast Mouse
regulation of nitrogen compound metabolic processGO:00511712510.181
organelle organizationGO:00069962270.178
Human Yeast Mouse
localization of cellGO:00516742440.178
organic cyclic compound biosynthetic processGO:19013622230.177
regulation of rna biosynthetic processGO:20011412130.175
regulation of primary metabolic processGO:00800903110.172
taxisGO:00423301090.169
apoptotic processGO:00069151160.169
protein complex biogenesisGO:0070271300.166
protein acylationGO:004354330.166
nucleic acid templated transcriptionGO:00976591810.164
transcription from rna polymerase ii promoterGO:0006366800.164
cell morphogenesisGO:00009022890.162
single organism organelle organizationGO:19025891990.161
Human Yeast
cellular macromolecule metabolic processGO:00442603910.160
Human Yeast Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.157
amine metabolic processGO:000930820.151
internal peptidyl lysine acetylationGO:001839320.144
internal protein amino acid acetylationGO:000647520.143
telomere organizationGO:003220010.138
Human Yeast
mitotic recombinationGO:000631220.135
Yeast
regulation of nucleobase containing compound metabolic processGO:00192192500.135
negative regulation of cellular processGO:00485232830.133
gene expressionGO:00104672520.133
double strand break repairGO:000630230.131
Human Yeast Mouse
telomere maintenanceGO:000072310.127
Human Yeast
camera type eye developmentGO:00430102220.124
double strand break repair via homologous recombinationGO:000072410.124
Human Yeast Mouse
biosynthetic processGO:00090582940.124
Human Yeast
peptidyl lysine acetylationGO:001839420.123
regulation of dna recombinationGO:000001820.122
response to chemicalGO:00422213200.121
transportGO:00068102200.119
Worm
developmental growthGO:00485891660.110
aromatic compound biosynthetic processGO:00194382170.108
nucleobase containing compound metabolic processGO:00061392740.108
Human Yeast Mouse
positive regulation of cellular amino acid metabolic processGO:004576400.106
nitrogen compound metabolic processGO:00068073190.106
Human Yeast Mouse
meiotic nuclear divisionGO:000712640.105
Yeast Mouse
cellular component movementGO:00069283350.103
regulation of cellular amino acid metabolic processGO:000652100.101
rna biosynthetic processGO:00327741810.100
multi organism processGO:00517041340.100
cell part morphogenesisGO:00329902460.098
cellular amine metabolic processGO:004410620.098
cell migrationGO:00164772370.097
positive regulation of biosynthetic processGO:0009891680.095
regulation of rna metabolic processGO:00512522240.092
nuclear transportGO:005116940.092
regulation of cellular amine metabolic processGO:003323800.091
organelle localizationGO:0051640490.089
cytokinesisGO:000091030.087
mitotic dna integrity checkpointGO:004477440.087
maintenance of locationGO:005123540.086
tube morphogenesisGO:00352393490.086
macromolecular complex subunit organizationGO:0043933740.086
regulation of transcription from rna polymerase ii promoterGO:00063571140.086
regionalizationGO:00030022740.085
regulation of cellular biosynthetic processGO:00313262450.084
embryonic digestive tract morphogenesisGO:004855730.082
protein modification processGO:00362111000.082
Yeast
cell motilityGO:00488702440.081
regulation of cellular ketone metabolic processGO:001056570.081
embryonic organ developmentGO:00485683810.080
cellular component morphogenesisGO:00329893360.079
nucleoside monophosphate catabolic processGO:000912540.079
reproductionGO:0000003400.078
Yeast Mouse
positive regulation of cellular amine metabolic processGO:003324000.078
cellular component disassemblyGO:002241110.078
mitotic dna damage checkpointGO:004477340.078
cellular ketone metabolic processGO:0042180110.077
negative regulation of macromolecule metabolic processGO:0010605760.077
dna catabolic processGO:000630810.076
cellular protein modification processGO:00064641000.074
Yeast
dna metabolic processGO:0006259270.074
Human Yeast Mouse
cell deathGO:00082191210.072
protein metabolic processGO:00195381830.072
Yeast
meiotic chromosome segregationGO:004513230.071
positive regulation of cellular biosynthetic processGO:0031328680.070
positive regulation of rna biosynthetic processGO:1902680570.067
regulation of synapse assemblyGO:005196330.067
regulation of response to stimulusGO:00485832690.066
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.065
multicellular organism growthGO:003526440.065
positive regulation of transcription dna templatedGO:0045893570.065
positive regulation of macromolecule biosynthetic processGO:0010557590.065
regulation of developmental processGO:00507932470.064
regulation of multicellular organism growthGO:004001440.063
negative regulation of mitotic cell cycleGO:0045930110.063
cellular response to external stimulusGO:007149620.063
cell morphogenesis involved in differentiationGO:00009041950.062
cellular carbohydrate metabolic processGO:004426240.062
response to external stimulusGO:00096052640.061
establishment of localizationGO:00512342440.061
Yeast Worm
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.061
protein complex subunit organizationGO:0071822460.060
digestive system developmentGO:00551232890.060
negative regulation of gene expressionGO:0010629650.058
cell projection morphogenesisGO:00488582440.057
behaviorGO:0007610740.057
multi organism reproductive processGO:0044703360.056
gene silencingGO:001645840.054
multicellular organismal reproductive processGO:0048609350.053
negative regulation of nitrogen compound metabolic processGO:0051172590.052
positive regulation of chromatin modificationGO:190331010.051
generation of neuronsGO:00486993850.050
positive regulation of histone modificationGO:003105810.050
neuron projection developmentGO:00311751800.050
single organism transportGO:00447652060.049
programmed cell deathGO:00125011190.048
small molecule metabolic processGO:0044281770.047
cell cycleGO:0007049930.047
Yeast Mouse
dna modificationGO:000630480.047
regulation of establishment of protein localizationGO:007020140.047
macromolecular complex disassemblyGO:003298410.047
peptidyl serine phosphorylationGO:001810510.047
gamete generationGO:0007276330.047
macromolecule modificationGO:00434121110.046
Yeast
protein alkylationGO:0008213130.046
oxoacid metabolic processGO:0043436310.046
double strand break repair via nonhomologous end joiningGO:000630310.045
deathGO:00162651210.045
head developmentGO:00603223030.044
positive regulation of macromolecule metabolic processGO:0010604930.043
protein complex assemblyGO:0006461300.043
cytoskeleton dependent cytokinesisGO:006164030.042
growthGO:00400071740.042
cellular protein metabolic processGO:00442671290.042
Yeast
negative regulation of rna biosynthetic processGO:1902679450.042
cellular response to lipopolysaccharideGO:007122230.041
regulation of extrinsic apoptotic signaling pathwayGO:200123630.041
extrinsic apoptotic signaling pathwayGO:009719130.041
negative regulation of response to stimulusGO:00485851040.041
organonitrogen compound metabolic processGO:1901564740.040
system processGO:00030081850.040
negative regulation of nucleobase containing compound metabolic processGO:0045934590.040
chromatin organizationGO:0006325220.039
negative regulation of rna metabolic processGO:0051253480.039
regulation of signalingGO:00230512350.038
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.038
negative regulation of transcription dna templatedGO:0045892450.038
developmental process involved in reproductionGO:0003006270.038
anatomical structure homeostasisGO:0060249360.038
Human Yeast Mouse
ribonucleoside monophosphate catabolic processGO:000915840.038
regulation of programmed cell deathGO:00430671010.038
positive regulation of nucleic acid templated transcriptionGO:1903508570.038
meiotic cell cycle processGO:190304630.038
Yeast
phosphorus metabolic processGO:00067931090.037
embryonic organ morphogenesisGO:00485622740.037
cell surface receptor signaling pathwayGO:00071663250.037
cellular macromolecular complex assemblyGO:0034622240.037
neuron developmentGO:00486662620.037
covalent chromatin modificationGO:0016569200.036
brain developmentGO:00074202930.035
dna biosynthetic processGO:007189730.035
chromatin modificationGO:0016568210.035
negative regulation of dna metabolic processGO:005105340.035
nucleocytoplasmic transportGO:000691340.035
digestive tract morphogenesisGO:00485462310.035
regulation of synaptic growth at neuromuscular junctionGO:000858210.035
signal transductionGO:00071654550.034
non recombinational repairGO:000072620.034
cellular amino acid metabolic processGO:000652070.034
regulation of cellular carbohydrate metabolic processGO:001067540.033
dna templated transcription elongationGO:000635430.033
chemotaxisGO:00069351040.032
regulation of biological qualityGO:00650082630.032
Human Yeast Mouse
embryonic digestive tract developmentGO:004856640.032
regulation of gene expression epigeneticGO:0040029110.032
positive regulation of rna metabolic processGO:0051254590.032
response to organic substanceGO:00100331530.032
atp catabolic processGO:000620040.032
neuron differentiationGO:00301823530.032
methylationGO:0032259220.032
mrna 3 end processingGO:003112420.032
positive regulation of gene expressionGO:0010628710.032
regulation of signal transductionGO:00099662250.031
regenerationGO:0031099910.031
cell agingGO:000756920.031
organelle assemblyGO:00709251100.029
fertilizationGO:000956630.029
neuron projection morphogenesisGO:00488121610.029
regulation of dna templated transcription elongationGO:003278430.029
regulation of cellular component organizationGO:0051128860.029
reproductive processGO:0022414400.028
regulation of apoptotic processGO:0042981980.028
positive regulation of cellular processGO:00485222010.028
Mouse
response to drugGO:004249330.028
adult behaviorGO:003053420.028
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.027
eye developmentGO:00016542770.027
cellular localizationGO:0051641970.027
single organism reproductive processGO:0044702400.027
regulation of meiotic cell cycleGO:005144510.027
negative regulation of cellular metabolic processGO:0031324770.027
protein heterooligomerizationGO:005129110.027
negative regulation of metabolic processGO:0009892860.026
segmentationGO:0035282970.026
pronuclear migrationGO:003504610.025
germ cell developmentGO:0007281220.025
hematopoietic stem cell migrationGO:003570140.025
negative regulation of nucleic acid templated transcriptionGO:1903507450.025
regulation of dna templated transcription in response to stressGO:004362000.025
purine ribonucleoside monophosphate catabolic processGO:000916940.025
carbohydrate biosynthetic processGO:001605110.025
cognitionGO:005089010.025
protein methylationGO:0006479130.025
cell morphogenesis involved in neuron differentiationGO:00486671630.025
cell proliferationGO:0008283800.025
Mouse
regulation of response to stressGO:0080134360.024
blood vessel developmentGO:00015682460.024
positive regulation of nucleobase containing compound metabolic processGO:0045935690.023
digestive tract developmentGO:00485652650.023
lipid storageGO:001991510.023
negative regulation of biosynthetic processGO:0009890550.023
maintenance of dna repeat elementsGO:004357020.022
response to abiotic stimulusGO:00096281220.022
regulation of growthGO:0040008420.022
multicellular organism reproductionGO:0032504350.022
negative regulation of nuclear divisionGO:005178430.022
sexual reproductionGO:0019953360.022
phosphorylationGO:0016310690.021
regulation of bindingGO:005109830.021
dorsal ventral pattern formationGO:00099531250.021
response to alkaloidGO:004327920.021
neuromuscular synaptic transmissionGO:000727420.021
camera type eye morphogenesisGO:00485931080.020
homeostatic processGO:00425921420.020
Human Yeast Mouse
immune system processGO:00023762410.020
Mouse
histone methylationGO:0016571130.020
carboxylic acid metabolic processGO:0019752220.020
response to organic cyclic compoundGO:0014070510.020
muscle structure developmentGO:00610611960.020
cellular response to extracellular stimulusGO:003166820.020
cellular response to stressGO:0033554620.020
Human Yeast Mouse
organic acid metabolic processGO:0006082310.020
negative regulation of cell communicationGO:0010648960.019
synaptic growth at neuromuscular junctionGO:005112420.019
oogenesisGO:0048477140.019
macromolecule methylationGO:0043414190.019
establishment of localization in cellGO:0051649770.019
axonogenesisGO:00074091520.019
regulation of protein metabolic processGO:0051246560.019
chemosensory behaviorGO:000763510.019
protein phosphorylationGO:0006468470.019
positive regulation of dna templated transcription elongationGO:003278610.019
somatic cell dna recombinationGO:001644410.019
histone h3 k4 methylationGO:005156820.018
i kappab kinase nf kappab signalingGO:000724940.018
apoptotic signaling pathwayGO:0097190230.018
regulation of mitotic cell cycleGO:0007346250.018
negative regulation of ras protein signal transductionGO:004658010.018
heart developmentGO:00075073130.018
positive regulation of protein metabolic processGO:0051247230.018
cell cycle g1 s phase transitionGO:004484310.018
regulation of gene silencingGO:006096810.018
positive regulation of molecular functionGO:0044093330.018
Worm
cellular response to chemical stimulusGO:00708871570.017
cell cycle arrestGO:000705010.017
autophagyGO:000691440.017
positive regulation of nitrogen compound metabolic processGO:0051173690.017
protein complex disassemblyGO:004324110.017
hatchingGO:003518840.017
spermatid developmentGO:000728620.017
regulation of endopeptidase activityGO:0052548230.017
b cell activationGO:004211320.017
development of primary female sexual characteristicsGO:004654540.017
mitotic g2 dna damage checkpointGO:000709530.017
negative regulation of synapse assemblyGO:005196420.017
reciprocal dna recombinationGO:003582510.017
Yeast
vasculature developmentGO:00019442780.017
negative regulation of signalingGO:0023057960.017
histone modificationGO:0016570200.017
spindle assemblyGO:005122520.016
negative regulation of signal transductionGO:0009968940.016
eye morphogenesisGO:00485921440.016
protein importGO:001703830.016
fin regenerationGO:0031101510.016
cellular process involved in reproduction in multicellular organismGO:0022412280.016
sensory organ morphogenesisGO:00905962000.016
positive regulation of dna metabolic processGO:005105410.016
establishment of protein localization to organelleGO:007259440.016
development of primary sexual characteristicsGO:004513750.016
mitotic cell cycle processGO:1903047480.016
female gamete generationGO:0007292140.016
single fertilizationGO:000733830.015
positive regulation of transportGO:005105020.015
regulation of carbohydrate biosynthetic processGO:004325510.015
peptidyl amino acid modificationGO:0018193160.015
sex determinationGO:000753010.015
positive regulation of cellular metabolic processGO:0031325940.015
meiosis iGO:000712710.015
Yeast
protein polymerizationGO:005125840.015
angiogenesisGO:00015251580.015
chordate embryonic developmentGO:00430092710.015
Mouse
positive regulation of carbohydrate metabolic processGO:004591310.015
cell fate commitmentGO:0045165990.015
negative regulation of apoptotic processGO:0043066550.015
response to inorganic substanceGO:0010035380.015
negative regulation of cellular biosynthetic processGO:0031327550.015
mitotic cell cycle phase transitionGO:004477290.015
establishment of organelle localizationGO:0051656450.015
spermatogenesisGO:000728370.014
cellular extravasationGO:004512310.014
cell fate specificationGO:0001708680.014
regulation of synapse organizationGO:005080730.014
regulation of cellular response to stressGO:0080135200.014
regulation of microtubule cytoskeleton organizationGO:007050730.013
positive regulation of metabolic processGO:00098931080.013
Worm
mitotic cell cycleGO:0000278640.013
retina morphogenesis in camera type eyeGO:0060042790.013
response to endogenous stimulusGO:0009719830.013
peptidyl serine modificationGO:001820920.013
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.013
blood vessel morphogenesisGO:00485142160.013
dna alkylationGO:000630580.013
protein localization to nucleusGO:003450430.013
nuclear exportGO:005116810.013
phosphate containing compound metabolic processGO:00067961080.013
ribosomal small subunit biogenesisGO:004227420.013
regulation of cell activationGO:005086510.013
epithelial tube morphogenesisGO:00605621480.013
regulation of cell communicationGO:00106462320.013
positive regulation of cellular protein metabolic processGO:0032270220.013
tissue regenerationGO:0042246740.013
negative regulation of small gtpase mediated signal transductionGO:005105810.013
regulation of protein transportGO:005122330.013
transcription elongation from rna polymerase ii promoterGO:000636830.013
wound healingGO:0042060900.013
positive regulation of cell activationGO:005086710.013
cell cycle processGO:0022402530.013
Yeast
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.013
positive regulation of synapse assemblyGO:005196510.012
response to amino acidGO:004320020.012
central nervous system developmentGO:00074173870.012
cytoskeleton organizationGO:0007010960.012
response to cadmium ionGO:0046686140.012
regulation of anatomical structure morphogenesisGO:00226031300.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
cellular component assembly involved in morphogenesisGO:00109271070.012
ameboidal type cell migrationGO:00016671430.012
single organism biosynthetic processGO:0044711710.012
Yeast
regulation of cell deathGO:00109411030.012
epithelial cell morphogenesisGO:000338220.012
rna transportGO:005065820.012
regulation of dna replicationGO:000627530.012
regulation of multicellular organismal processGO:00512392770.012
response to woundingGO:00096111160.012
regulation of cellular protein metabolic processGO:0032268520.012
positive regulation of cellular carbohydrate metabolic processGO:001067610.011
intracellular signal transductionGO:0035556850.011
cell cycle g2 m phase transitionGO:004483940.011
protein stabilizationGO:005082120.011
retina development in camera type eyeGO:00600411460.011
negative regulation of programmed cell deathGO:0043069580.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
Mouse
recombinational repairGO:000072510.011
Human Yeast Mouse
negative regulation of macromolecule biosynthetic processGO:0010558480.011
positive regulation of chromosome organizationGO:200125210.011
positive regulation of cytoskeleton organizationGO:005149530.011
cellular response to organic substanceGO:00713101050.011
g2 m transition of mitotic cell cycleGO:000008640.011
regulation of carbohydrate metabolic processGO:000610940.011
cranial nerve developmentGO:0021545420.011
sensory organ developmentGO:00074233930.011
rna localizationGO:000640340.011
production of molecular mediator of immune responseGO:000244020.011
spermatid differentiationGO:004851520.011
nuclear importGO:005117030.011
regulation of stem cell proliferationGO:007209120.011
g1 s transition of mitotic cell cycleGO:000008210.011
positive regulation of cell cycleGO:004578730.011
response to steroid hormoneGO:0048545350.011
mrna transportGO:005102820.011
regulation of oxidative stress induced cell deathGO:190320120.011
cell projection organizationGO:00300302840.011
response to uvGO:000941130.010
positive regulation of cellular component biogenesisGO:004408930.010
single organism intracellular transportGO:1902582250.010
vesicle mediated transportGO:0016192220.010
Worm
regulation of protein complex assemblyGO:004325430.010
response to metal ionGO:0010038340.010
mitotic g2 m transition checkpointGO:004481830.010
intracellular transportGO:0046907320.010

rpa1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.079
nervous system diseaseDOID:86300.023
sensory system diseaseDOID:005015500.014
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
cancerDOID:16200.012
disease of metabolismDOID:001466700.012