Danio rerio

20 known processes

prop1

PROP paired-like homeobox 1

(Aliases: si:ch211-93n23.5)

prop1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.105
response to chemicalGO:00422213200.090
cellular macromolecule metabolic processGO:00442603910.086
Zebrafish Mouse Worm
negative regulation of cellular processGO:00485232830.077
Mouse
regulation of cellular metabolic processGO:00313233200.076
Zebrafish Mouse Worm
signal transductionGO:00071654550.075
Mouse
tube morphogenesisGO:00352393490.069
positive regulation of biological processGO:00485182530.068
Zebrafish Mouse Worm
regulation of nucleobase containing compound metabolic processGO:00192192500.067
Zebrafish Mouse Worm
response to external stimulusGO:00096052640.067
agingGO:000756820.064
cell motilityGO:00488702440.064
Zebrafish Mouse
establishment of protein localization to organelleGO:007259440.061
brain developmentGO:00074202930.060
cellular aromatic compound metabolic processGO:00067252950.060
Zebrafish Mouse Worm
aromatic compound biosynthetic processGO:00194382170.059
Zebrafish Mouse Worm
maintenance of locationGO:005123540.059
regulation of metabolic processGO:00192223590.058
Zebrafish Mouse Worm
nucleic acid metabolic processGO:00903042440.057
Zebrafish Mouse Worm
cellular biosynthetic processGO:00442492860.056
Zebrafish Mouse Worm
organic cyclic compound biosynthetic processGO:19013622230.054
Zebrafish Mouse Worm
protein localization to nucleusGO:003450430.053
chemosensory behaviorGO:000763510.053
multicellular organism growthGO:003526440.052
cellular nitrogen compound metabolic processGO:00346412900.052
Zebrafish Mouse Worm
nuclear transportGO:005116940.051
regulation of multicellular organismal processGO:00512392770.050
response to stressGO:00069502630.050
developmental growthGO:00485891660.048
regulation of macromolecule metabolic processGO:00602553170.047
Zebrafish Mouse Worm
protein importGO:001703830.047
nucleocytoplasmic transportGO:000691340.046
regulation of biosynthetic processGO:00098892500.046
Zebrafish Mouse Worm
positive regulation of cellular component biogenesisGO:004408930.046
regulation of multicellular organism growthGO:004001440.046
nucleobase containing compound biosynthetic processGO:00346542050.045
Zebrafish Mouse Worm
cellular nitrogen compound biosynthetic processGO:00442712180.044
Zebrafish Mouse Worm
nitrogen compound metabolic processGO:00068073190.044
Zebrafish Mouse Worm
single organism nuclear importGO:190259330.044
blood vessel developmentGO:00015682460.044
Mouse
protein import into nucleusGO:000660630.043
camera type eye developmentGO:00430102220.042
Zebrafish
vasculature developmentGO:00019442780.042
Mouse
regulation of primary metabolic processGO:00800903110.041
Zebrafish Mouse Worm
nucleic acid templated transcriptionGO:00976591810.041
Zebrafish Mouse Worm
regulation of developmental processGO:00507932470.040
protein targeting to nucleusGO:004474430.040
female gonad developmentGO:000858540.040
positive regulation of catabolic processGO:000989640.040
central nervous system developmentGO:00074173870.039
gland developmentGO:00487321430.039
embryonic organ developmentGO:00485683810.039
Zebrafish
organic cyclic compound metabolic processGO:19013603010.039
Zebrafish Mouse Worm
female sex differentiationGO:004666040.039
cellular response to extracellular stimulusGO:003166820.039
immune system processGO:00023762410.038
regulation of multicellular organismal developmentGO:20000262230.038
cell projection morphogenesisGO:00488582440.038
sensory organ developmentGO:00074233930.038
Zebrafish
generation of neuronsGO:00486993850.037
Zebrafish Worm
regulation of establishment of protein localizationGO:007020140.037
pigment granule localizationGO:0051875250.037
embryo development ending in birth or egg hatchingGO:00097922710.037
Zebrafish
macromolecule biosynthetic processGO:00090592270.037
Zebrafish Mouse Worm
homeostatic processGO:00425921420.036
morphogenesis of an epitheliumGO:00020093330.036
nuclear importGO:005117030.036
cellular response to molecule of bacterial originGO:007121930.036
organic substance biosynthetic processGO:19015762890.036
Zebrafish Mouse Worm
regulation of rna biosynthetic processGO:20011412130.035
Zebrafish Mouse Worm
system processGO:00030081850.035
regulation of nitrogen compound metabolic processGO:00511712510.035
Zebrafish Mouse Worm
regulation of protein transportGO:005122330.034
lipid storageGO:001991510.034
regulation of cellular amine metabolic processGO:003323800.034
cellular amine metabolic processGO:004410620.033
rna metabolic processGO:00160702190.033
Zebrafish Mouse Worm
gastrulationGO:00073692080.033
positive regulation of transportGO:005105020.033
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.033
digestive tract morphogenesisGO:00485462310.033
establishment of localizationGO:00512342440.033
single organism metabolic processGO:00447102170.032
transcription dna templatedGO:00063511810.032
Zebrafish Mouse Worm
regulation of biological qualityGO:00650082630.032
development of primary female sexual characteristicsGO:004654540.032
gene expressionGO:00104672520.032
Zebrafish Mouse Worm
diencephalon developmentGO:0021536580.032
regulation of synapse assemblyGO:005196330.031
regulation of cellular amino acid metabolic processGO:000652100.031
cell surface receptor signaling pathwayGO:00071663250.031
Mouse
response to drugGO:004249330.031
rna biosynthetic processGO:00327741810.031
Zebrafish Mouse Worm
negative regulation of biological processGO:00485193040.031
Mouse
response to organic substanceGO:00100331530.031
cellular macromolecule biosynthetic processGO:00346452240.030
Zebrafish Mouse Worm
regulation of cell activationGO:005086510.030
heterocycle biosynthetic processGO:00181302150.030
Zebrafish Mouse Worm
negative regulation of protein phosphorylationGO:000193340.030
connective tissue developmentGO:0061448990.029
sequestering of calcium ionGO:005120830.029
pancreas developmentGO:0031016840.029
regulation of synapse organizationGO:005080730.029
mitochondrion organizationGO:000700540.029
peptidyl serine modificationGO:001820920.028
positive regulation of cytosolic calcium ion concentrationGO:000720440.028
synaptic growth at neuromuscular junctionGO:005112420.028
localization of cellGO:00516742440.028
Zebrafish Mouse
digestive system developmentGO:00551232890.028
positive regulation of cellular amino acid metabolic processGO:004576400.027
negative regulation of sequestering of calcium ionGO:005128340.027
cell migrationGO:00164772370.027
Zebrafish Mouse
regulation of cytoplasmic transportGO:190364940.027
negative regulation of macromolecule metabolic processGO:0010605760.027
Mouse
apoptotic processGO:00069151160.027
Mouse
cellular response to external stimulusGO:007149620.027
response to glucoseGO:000974930.027
skeletal system developmentGO:00015011810.026
regulation of protein import into nucleusGO:004230620.026
blood vessel morphogenesisGO:00485142160.026
regulation of response to stimulusGO:00485832690.026
amine metabolic processGO:000930820.026
regionalizationGO:00030022740.026
Zebrafish Mouse
regulation of protein targetingGO:190353320.026
regulation of protein localization to nucleusGO:190018020.026
eye developmentGO:00016542770.026
Zebrafish
regulation of reproductive processGO:200024140.026
hematopoietic or lymphoid organ developmentGO:00485341910.025
transportGO:00068102200.025
positive regulation of cellular amine metabolic processGO:003324000.025
nucleobase containing compound metabolic processGO:00061392740.025
Zebrafish Mouse Worm
positive regulation of cellular processGO:00485222010.025
Zebrafish Mouse Worm
angiogenesisGO:00015251580.025
digestive tract developmentGO:00485652650.025
regulation of metal ion transportGO:001095940.025
cell part morphogenesisGO:00329902460.025
response to nutrientGO:000758430.025
guanosine containing compound catabolic processGO:190106920.024
cellular component movementGO:00069283350.024
Zebrafish Mouse
regulation of cellular ketone metabolic processGO:001056570.024
negative regulation of protein transportGO:005122430.024
response to hexoseGO:000974630.024
regulation of extrinsic apoptotic signaling pathwayGO:200123630.024
regulation of synaptic growth at neuromuscular junctionGO:000858210.024
growthGO:00400071740.024
extrinsic apoptotic signaling pathwayGO:009719130.023
response to monosaccharideGO:003428430.023
adherens junction organizationGO:003433240.023
convergent extensionGO:00600261180.023
forebrain developmentGO:0030900960.023
regulation of nucleic acid templated transcriptionGO:19035062130.023
Zebrafish Mouse Worm
cellular response to nutrient levelsGO:003166920.023
embryonic organ morphogenesisGO:00485622740.023
Zebrafish
cellular localizationGO:0051641970.023
cellular response to chemical stimulusGO:00708871570.023
regulation of intracellular protein transportGO:003315730.023
autophagyGO:000691440.023
regulation of reactive oxygen species metabolic processGO:200037720.023
neuron projection developmentGO:00311751800.022
carbohydrate homeostasisGO:003350010.022
regulation of calcium ion transportGO:005192420.022
heterocycle metabolic processGO:00464832900.022
Zebrafish Mouse Worm
oxoacid metabolic processGO:0043436310.022
regulation of synaptic plasticityGO:004816710.022
negative regulation of kinase activityGO:003367340.022
regulation of neuronal synaptic plasticityGO:004816810.022
cellular response to biotic stimulusGO:007121630.022
cellular component disassemblyGO:002241110.022
regulation of cellular biosynthetic processGO:00313262450.022
Zebrafish Mouse Worm
regulation of transcription dna templatedGO:00063552130.022
Zebrafish Mouse Worm
negative regulation of protein kinase activityGO:000646940.022
response to carbohydrateGO:000974330.021
cellular response to starvationGO:000926710.021
regulation of cell communicationGO:00106462320.021
post embryonic morphogenesisGO:000988640.021
segmentationGO:0035282970.021
Zebrafish
locomotionGO:00400113130.021
Zebrafish Mouse Worm
ear developmentGO:00435831270.021
cellular amino acid metabolic processGO:000652070.021
negative regulation of metabolic processGO:0009892860.021
Mouse
leukocyte proliferationGO:007066110.021
cellular ketone metabolic processGO:0042180110.021
synaptic vesicle transportGO:004848910.020
lymphocyte proliferationGO:004665110.020
b cell activationGO:004211320.020
ovulation cycleGO:004269820.020
peptidyl serine phosphorylationGO:001810510.020
positive regulation of dna metabolic processGO:005105410.020
positive regulation of metabolic processGO:00098931080.020
Zebrafish Mouse Worm
regulation of dendrite developmentGO:005077330.020
deathGO:00162651210.020
Mouse
phagocytosisGO:000690930.020
chordate embryonic developmentGO:00430092710.019
Zebrafish
gtp metabolic processGO:004603940.019
guanosine containing compound metabolic processGO:190106840.019
single organism localizationGO:19025782250.019
positive regulation of immune effector processGO:000269930.019
determination of left right symmetryGO:00073681790.019
regulation of circadian rhythmGO:004275240.019
regulation of nucleocytoplasmic transportGO:004682220.019
sequestering of metal ionGO:005123830.019
multi organism processGO:00517041340.019
enzyme linked receptor protein signaling pathwayGO:00071671060.019
production of molecular mediator of immune responseGO:000244020.019
glucose homeostasisGO:004259310.019
hepaticobiliary system developmentGO:0061008980.019
lipid homeostasisGO:005508830.019
lipid catabolic processGO:001604240.019
cellular carbohydrate metabolic processGO:004426240.019
transmembrane transportGO:00550851200.019
ion transmembrane transportGO:0034220910.019
stem cell proliferationGO:007208940.019
negative regulation of nucleocytoplasmic transportGO:004682320.019
regulation of gene expressionGO:00104682650.019
Zebrafish Mouse Worm
cartilage developmentGO:0051216960.019
regulation of protein complex assemblyGO:004325430.019
ovulation cycle processGO:002260220.019
wound healingGO:0042060900.018
regulation of autophagyGO:001050630.018
regulation of macromolecule biosynthetic processGO:00105562250.018
Zebrafish Mouse Worm
cell morphogenesis involved in neuron differentiationGO:00486671630.018
cellular component morphogenesisGO:00329893360.018
programmed cell deathGO:00125011190.018
Mouse
head developmentGO:00603223030.018
periodic partitioningGO:000736510.018
transcription from rna polymerase ii promoterGO:0006366800.018
Mouse Worm
anterior posterior pattern specificationGO:00099521520.018
Zebrafish
small molecule metabolic processGO:0044281770.018
protein secretionGO:000930610.018
urogenital system developmentGO:0001655970.018
regulation of bindingGO:005109830.018
carboxylic acid metabolic processGO:0019752220.018
pigmentationGO:0043473850.018
cell morphogenesis involved in differentiationGO:00009041950.018
epithelial tube morphogenesisGO:00605621480.018
fertilizationGO:000956630.018
hemopoiesisGO:00300971830.018
regulation of cytokine productionGO:000181730.018
mononuclear cell proliferationGO:003294310.018
antimicrobial humoral responseGO:001973020.017
neuron differentiationGO:00301823530.017
Zebrafish Worm
regulation of cellular macromolecule biosynthetic processGO:20001122220.017
Zebrafish Mouse Worm
tissue remodelingGO:004877140.017
cell projection organizationGO:00300302840.017
single organism transportGO:00447652060.017
neuron projection morphogenesisGO:00488121610.017
meiotic nuclear divisionGO:000712640.017
regulation of rna metabolic processGO:00512522240.017
Zebrafish Mouse Worm
neuron developmentGO:00486662620.017
biosynthetic processGO:00090582940.017
Zebrafish Mouse Worm
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
negative regulation of cytoplasmic transportGO:190365020.017
b cell differentiationGO:003018310.017
negative regulation of map kinase activityGO:004340720.017
response to other organismGO:0051707970.017
cell morphogenesisGO:00009022890.017
positive regulation of reproductive processGO:200024320.017
response to external biotic stimulusGO:0043207970.017
organic acid metabolic processGO:0006082310.017
cellular protein catabolic processGO:004425740.016
cellular amide metabolic processGO:004360340.016
cytokinesisGO:000091030.016
regulation of dendrite morphogenesisGO:004881430.016
gtp catabolic processGO:000618420.016
sensory organ morphogenesisGO:00905962000.016
Zebrafish
cellular protein metabolic processGO:00442671290.016
positive regulation of cellular catabolic processGO:003133130.016
axonogenesisGO:00074091520.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.016
negative regulation of nitrogen compound metabolic processGO:0051172590.015
Mouse
stem cell maintenanceGO:001982740.015
regulation of anatomical structure morphogenesisGO:00226031300.015
compound eye developmentGO:004874920.015
regulation of cellular carbohydrate metabolic processGO:001067540.015
regulation of signal transductionGO:00099662250.015
pole plasm assemblyGO:000731540.015
proteolysis involved in cellular protein catabolic processGO:005160330.015
developmental growth involved in morphogenesisGO:0060560860.015
organelle localizationGO:0051640490.015
response to abiotic stimulusGO:00096281220.015
regenerationGO:0031099910.015
positive regulation of apoptotic signaling pathwayGO:200123510.015
multicellular organismal response to stressGO:003355520.015
response to woundingGO:00096111160.015
cellular pigmentationGO:0033059300.015
renal system developmentGO:0072001940.015
interspecies interaction between organismsGO:004441940.015
regulation of sequestering of calcium ionGO:005128240.015
oocyte anterior posterior axis specificationGO:000731440.015
peptide metabolic processGO:000651810.015
inner ear developmentGO:00488391260.015
modification dependent protein catabolic processGO:001994130.015
tissue regenerationGO:0042246740.014
liver developmentGO:0001889960.014
organonitrogen compound metabolic processGO:1901564740.014
germ line stem cell maintenanceGO:003071820.014
cellular response to organic substanceGO:00713101050.014
modification dependent macromolecule catabolic processGO:004363230.014
intracellular signal transductionGO:0035556850.014
regulation of dna replicationGO:000627530.014
regulation of ion transmembrane transporter activityGO:003241220.014
determination of bilateral symmetryGO:00098552040.014
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.014
negative regulation of intracellular protein transportGO:009031730.014
eye morphogenesisGO:00485921440.014
Zebrafish
developmental programmed cell deathGO:001062340.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
Zebrafish Mouse Worm
response to amineGO:001407510.014
negative regulation of cell communicationGO:0010648960.014
multi organism cellular processGO:004476420.014
synaptic vesicle localizationGO:009747910.014
negative regulation of reproductive processGO:200024230.014
establishment of pigment granule localizationGO:0051905220.014
negative regulation of intracellular transportGO:003238730.013
ubiquitin dependent protein catabolic processGO:000651130.013
peptide transportGO:001583310.013
locomotor rhythmGO:004547530.013
muscle structure developmentGO:00610611960.013
embryonic pattern specificationGO:0009880440.013
Zebrafish
regulation of molecular functionGO:0065009700.013
regulation of response to biotic stimulusGO:000283120.013
response to endogenous stimulusGO:0009719830.013
phosphate containing compound metabolic processGO:00067961080.013
neurotransmitter transportGO:000683620.013
regulation of jak stat cascadeGO:004642530.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
energy reserve metabolic processGO:000611220.013
adult behaviorGO:003053420.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
positive regulation of cell cycleGO:004578730.013
regulation of stem cell differentiationGO:200073640.013
establishment of localization in cellGO:0051649770.013
neuroblast proliferationGO:000740520.013
response to bacteriumGO:0009617580.013
regulation of erk1 and erk2 cascadeGO:007037240.013
heart morphogenesisGO:00030071560.013
Zebrafish
striated muscle tissue developmentGO:00147061100.013
negative regulation of protein import into nucleusGO:004230820.013
neurological system processGO:0050877620.013
cognitionGO:005089010.013
axon developmentGO:00615641660.013
establishment of organelle localizationGO:0051656450.013
release of sequestered calcium ion into cytosolGO:005120930.013
establishment of synaptic vesicle localizationGO:009748010.013
muscle cell differentiationGO:00426921390.013
stem cell divisionGO:001714510.013
regulation of carbohydrate metabolic processGO:000610940.013
negative regulation of rna metabolic processGO:0051253480.013
Mouse
regulation of organ growthGO:004662030.013
inositol lipid mediated signalingGO:004801720.013
regulation of protein catabolic processGO:004217610.012
negative regulation of stem cell differentiationGO:200073720.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
membrane fusionGO:006102520.012
maternal determination of anterior posterior axis embryoGO:000835840.012
negative regulation of defense responseGO:003134820.012
negative regulation of cell deathGO:0060548600.012
Mouse
negative regulation of apoptotic processGO:0043066550.012
Mouse
glucose importGO:004632320.012
erk1 and erk2 cascadeGO:007037140.012
single organism cellular localizationGO:1902580460.012
regulation of signalingGO:00230512350.012
regulation of cell developmentGO:00602841000.012
water homeostasisGO:003010440.012
cellular modified amino acid metabolic processGO:000657530.012
phosphorus metabolic processGO:00067931090.012
specification of symmetryGO:00097992040.012
notochord developmentGO:0030903540.012
homeostasis of number of cellsGO:0048872620.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.012
protein metabolic processGO:00195381830.012
Worm
exocytosisGO:000688710.012
hormone secretionGO:004687920.012
synaptic transmission cholinergicGO:000727140.012
protein polymerizationGO:005125840.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
protein modification processGO:00362111000.012
cell killingGO:000190620.012
meiotic cell cycle processGO:190304630.012
regulation of meiotic cell cycleGO:005144510.012
macromolecule modificationGO:00434121110.012
cation transportGO:0006812810.012
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.012
cell migration involved in gastrulationGO:0042074790.012
negative regulation of protein localization to nucleusGO:190018120.012
negative regulation of signalingGO:0023057960.012
carbohydrate biosynthetic processGO:001605110.012
negative regulation of nuclear divisionGO:005178430.012
positive regulation of cytoskeleton organizationGO:005149530.012
regulation of inflammatory responseGO:005072720.012
single organism organelle organizationGO:19025891990.012
cellular component biogenesisGO:00440851780.012
regulation of systemic arterial blood pressureGO:000307310.012
response to biotic stimulusGO:0009607970.012
negative regulation of mapk cascadeGO:004340940.012
neuron projection extensionGO:1990138450.012
neuron projection guidanceGO:0097485860.012
superoxide metabolic processGO:000680120.011
positive regulation of leukocyte differentiationGO:190210710.011
positive regulation of cytokine productionGO:000181920.011
peptidyl lysine acetylationGO:001839420.011
regulation of neural precursor cell proliferationGO:200017730.011
chemical homeostasisGO:0048878490.011
positive regulation of cellular metabolic processGO:0031325940.011
Zebrafish Mouse Worm
protein acylationGO:004354330.011
positive regulation of map kinase activityGO:004340630.011
internal protein amino acid acetylationGO:000647520.011
convergent extension involved in gastrulationGO:0060027710.011
single organism membrane fusionGO:004480120.011
neurotransmitter secretionGO:000726920.011
amino acid transportGO:000686520.011
negative regulation of epithelial cell proliferationGO:005068010.011
regulation of neurogenesisGO:0050767870.011
regulation of transporter activityGO:003240920.011
proteasomal protein catabolic processGO:001049820.011
gabaergic neuron differentiationGO:009715420.011
regulation of organelle assemblyGO:190211540.011
cell deathGO:00082191210.011
Mouse
positive regulation of lipid metabolic processGO:004583410.011
regulation of purine nucleotide catabolic processGO:003312120.011
regulation of hormone secretionGO:004688320.011
positive regulation of secretion by cellGO:190353210.011
negative regulation of response to stimulusGO:00485851040.011
negative regulation of catabolic processGO:000989530.011
ion transportGO:00068111140.011
macromolecule localizationGO:0033036540.011
kidney developmentGO:0001822920.011
phosphorylationGO:0016310690.011
epithelial cell differentiationGO:00308551160.011
protein acetylationGO:000647320.011
positive regulation of jnk cascadeGO:004633030.011
protein localizationGO:0008104400.011
calcium ion homeostasisGO:0055074190.011
negative regulation of mitosisGO:004583930.011
pronephros developmentGO:0048793690.011
endocrine system developmentGO:0035270650.011
multicellular organismal metabolic processGO:004423620.010
sprouting angiogenesisGO:0002040530.010
embryonic heart tube developmentGO:00350501330.010
Zebrafish
skeletal system morphogenesisGO:00487051020.010
cellular response to lipopolysaccharideGO:007122230.010
reactive oxygen species metabolic processGO:007259360.010
cellular protein modification processGO:00064641000.010
regulation of receptor mediated endocytosisGO:004825940.010
apoptotic process involved in developmentGO:190274220.010
immune system developmentGO:00025201910.010
chemotaxisGO:00069351040.010
regulation of programmed cell deathGO:00430671010.010
Mouse
endosomal transportGO:001619720.010
protein heterooligomerizationGO:005129110.010
cell substrate adhesionGO:003158940.010
mitochondrial transportGO:000683920.010
translational initiationGO:000641330.010
positive regulation of cell activationGO:005086710.010
internal peptidyl lysine acetylationGO:001839320.010

prop1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.017
disease of metabolismDOID:001466700.016
musculoskeletal system diseaseDOID:1700.015
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
immune system diseaseDOID:291400.013