Danio rerio

45 known processes

ikbkg

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

(Aliases: wu:fj33c07,nemo,fj33c07,zgc:113492)

ikbkg biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
signal transductionGO:00071654550.184
cell surface receptor signaling pathwayGO:00071663250.170
regulation of signal transductionGO:00099662250.169
cellular response to nutrient levelsGO:003166920.160
response to stressGO:00069502630.147
Human Mouse
regulation of signalingGO:00230512350.146
stem cell proliferationGO:007208940.140
cellular protein catabolic processGO:004425740.132
ubiquitin dependent protein catabolic processGO:000651130.112
regulation of response to stimulusGO:00485832690.111
autophagyGO:000691440.107
single organism transportGO:00447652060.105
establishment of protein localization to organelleGO:007259440.102
cell migrationGO:00164772370.098
larval developmentGO:000216420.098
cellular response to external stimulusGO:007149620.087
modification dependent protein catabolic processGO:001994130.085
negative regulation of biological processGO:00485193040.080
Mouse
establishment of localizationGO:00512342440.076
cellular response to starvationGO:000926710.075
transportGO:00068102200.074
cell projection morphogenesisGO:00488582440.074
Zebrafish
digestive tract developmentGO:00485652650.073
protein metabolic processGO:00195381830.072
meiotic nuclear divisionGO:000712640.072
locomotionGO:00400113130.065
positive regulation of defense response to virus by hostGO:000223000.065
regulation of cell communicationGO:00106462320.064
phagocytosisGO:000690930.062
nitrogen compound metabolic processGO:00068073190.060
Human
growthGO:00400071740.059
cellular component movementGO:00069283350.059
positive regulation of cellular processGO:00485222010.059
cellular response to extracellular stimulusGO:003166820.058
proteasomal protein catabolic processGO:001049820.058
negative regulation of cellular processGO:00485232830.058
Mouse
neuroblast proliferationGO:000740520.057
neuron projection developmentGO:00311751800.057
Zebrafish
agingGO:000756820.057
modification dependent macromolecule catabolic processGO:004363230.056
regulation of defense response to virus by hostGO:005069110.054
cellular protein metabolic processGO:00442671290.054
neuron developmentGO:00486662620.054
Zebrafish
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.053
intracellular signal transductionGO:0035556850.053
maintenance of locationGO:005123540.052
developmental growthGO:00485891660.051
multicellular organism growthGO:003526440.050
single organism metabolic processGO:00447102170.049
Mouse
positive regulation of biological processGO:00485182530.049
single organism localizationGO:19025782250.049
cell morphogenesisGO:00009022890.048
Zebrafish
defense responseGO:0006952470.048
positive regulation of transportGO:005105020.048
cellular component morphogenesisGO:00329893360.046
Zebrafish
cellular amine metabolic processGO:004410620.046
regulation of macromolecule metabolic processGO:00602553170.045
Human Mouse
b cell activationGO:004211320.045
regulation of multicellular organismal developmentGO:20000262230.044
positive regulation of immune effector processGO:000269930.044
regulation of stem cell proliferationGO:007209120.044
regulation of metabolic processGO:00192223590.044
Human Mouse
negative regulation of response to stimulusGO:00485851040.044
Mouse
regulation of protein catabolic processGO:004217610.043
lipid storageGO:001991510.043
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.043
cell morphogenesis involved in differentiationGO:00009041950.042
Zebrafish
lipid catabolic processGO:001604240.042
proteolysis involved in cellular protein catabolic processGO:005160330.042
tube morphogenesisGO:00352393490.041
digestive system developmentGO:00551232890.041
amine metabolic processGO:000930820.041
neurotransmitter transportGO:000683620.041
response to chemicalGO:00422213200.041
reactive nitrogen species metabolic processGO:200105700.040
cell motilityGO:00488702440.040
macromolecule modificationGO:00434121110.040
negative regulation of signal transductionGO:0009968940.040
Mouse
central nervous system developmentGO:00074173870.040
regulation of biological qualityGO:00650082630.039
Mouse
organonitrogen compound metabolic processGO:1901564740.039
cellular macromolecule metabolic processGO:00442603910.038
cellular response to chemical stimulusGO:00708871570.038
regulation of jak stat cascadeGO:004642530.038
regulation of peptidyl tyrosine phosphorylationGO:005073010.038
regulation of reactive oxygen species metabolic processGO:200037720.038
golgi vesicle transportGO:004819330.037
adult behaviorGO:003053420.037
nucleobase containing compound metabolic processGO:00061392740.037
Human
deathGO:00162651210.037
Mouse
regulation of rna metabolic processGO:00512522240.037
Human
single organism organelle organizationGO:19025891990.036
regulation of cellular amine metabolic processGO:003323800.036
negative regulation of protein phosphorylationGO:000193340.036
phosphate containing compound metabolic processGO:00067961080.035
regulation of transcription dna templatedGO:00063552130.035
Human
cellular biosynthetic processGO:00442492860.035
Human
cytoskeleton organizationGO:0007010960.035
heterocycle metabolic processGO:00464832900.035
Human
positive regulation of i kappab kinase nf kappab signalingGO:004312330.035
programmed cell deathGO:00125011190.034
Mouse
morphogenesis of an epitheliumGO:00020093330.034
cellular protein modification processGO:00064641000.034
neuron differentiationGO:00301823530.033
Zebrafish
cellular amino acid metabolic processGO:000652070.033
regulation of cell shapeGO:000836010.033
apoptotic processGO:00069151160.033
Mouse
nucleic acid metabolic processGO:00903042440.033
Human
regulation of tyrosine phosphorylation of stat3 proteinGO:004251610.033
regulation of biosynthetic processGO:00098892500.032
Human
regulation of nitrogen compound metabolic processGO:00511712510.032
Human
macroautophagyGO:001623610.032
response to ketoneGO:190165410.032
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.032
vasculature developmentGO:00019442780.032
stem cell divisionGO:001714510.031
generation of neuronsGO:00486993850.031
Zebrafish
regulation of tyrosine phosphorylation of stat proteinGO:004250910.031
regulation of cellular metabolic processGO:00313233200.031
Human Mouse
i kappab kinase nf kappab signalingGO:000724940.031
regulation of multicellular organismal processGO:00512392770.031
positive regulation of cellular catabolic processGO:003133130.030
aromatic compound biosynthetic processGO:00194382170.030
Human
protein polyubiquitinationGO:000020940.030
vacuolar transportGO:000703420.030
regulation of multicellular organism growthGO:004001440.030
production of molecular mediator of immune responseGO:000244020.030
heterocycle biosynthetic processGO:00181302150.029
Human
regulation of developmental processGO:00507932470.029
protein modification processGO:00362111000.029
positive regulation of catabolic processGO:000989640.029
cell part morphogenesisGO:00329902460.029
Zebrafish
regulation of nucleobase containing compound metabolic processGO:00192192500.029
Human
regulation of cellular ketone metabolic processGO:001056570.028
gastrulationGO:00073692080.028
cellular response to stressGO:0033554620.028
Human Mouse
regulation of production of molecular mediator of immune responseGO:000270010.028
neurotransmitter secretionGO:000726920.028
cellular amide metabolic processGO:004360340.027
tyrosine phosphorylation of stat proteinGO:000726010.027
nik nf kappab signalingGO:003806110.027
Mouse
meiotic cell cycle processGO:190304630.027
organic cyclic compound metabolic processGO:19013603010.026
Human
neuron projection morphogenesisGO:00488121610.026
Zebrafish
phosphorylationGO:0016310690.026
single organism cellular localizationGO:1902580460.026
regulation of synapse organizationGO:005080730.025
single organism membrane fusionGO:004480120.025
nuclear transportGO:005116940.025
immunoglobulin mediated immune responseGO:001606430.025
brain developmentGO:00074202930.025
cell morphogenesis involved in neuron differentiationGO:00486671630.025
Zebrafish
regulation of hormone secretionGO:004688320.025
rna localizationGO:000640340.024
b cell differentiationGO:003018310.024
digestive tract morphogenesisGO:00485462310.024
catecholamine metabolic processGO:000658420.024
cell projection organizationGO:00300302840.024
Zebrafish
centrosome cycleGO:000709810.024
regulation of cellular amino acid metabolic processGO:000652100.024
exocytosisGO:000688710.023
cell deathGO:00082191210.023
Mouse
regulation of response to stressGO:0080134360.023
Mouse
regulation of cellular protein catabolic processGO:190336210.023
regulation of i kappab kinase nf kappab signalingGO:004312240.023
regulation of protein complex assemblyGO:004325430.023
cellular component biogenesisGO:00440851780.023
fertilizationGO:000956630.023
regulation of anatomical structure morphogenesisGO:00226031300.023
establishment of localization in cellGO:0051649770.023
localization of cellGO:00516742440.023
response to drugGO:004249330.023
cellular modified amino acid metabolic processGO:000657530.023
response to organic substanceGO:00100331530.023
oxoacid metabolic processGO:0043436310.022
negative regulation of signalingGO:0023057960.022
Mouse
cellular localizationGO:0051641970.022
positive regulation of cytokine productionGO:000181920.022
endosomal transportGO:001619720.022
embryo development ending in birth or egg hatchingGO:00097922710.022
rna metabolic processGO:00160702190.022
Human
spermatid differentiationGO:004851520.022
enzyme linked receptor protein signaling pathwayGO:00071671060.022
female sex differentiationGO:004666040.022
biosynthetic processGO:00090582940.021
Human
regulation of protein metabolic processGO:0051246560.021
Mouse
membrane lipid biosynthetic processGO:004646720.021
regulation of intracellular signal transductionGO:1902531570.021
establishment of protein localization to vacuoleGO:007266610.021
protein localization to vacuoleGO:007266510.021
positive regulation of secretionGO:005104710.021
regulation of rna biosynthetic processGO:20011412130.021
Human
membrane invaginationGO:001032410.021
cellular ketone metabolic processGO:0042180110.021
erk1 and erk2 cascadeGO:007037140.021
regulation of neurogenesisGO:0050767870.021
establishment of organelle localizationGO:0051656450.021
membrane fusionGO:006102520.021
lymphocyte proliferationGO:004665110.021
response to external stimulusGO:00096052640.020
actin polymerization or depolymerizationGO:000815420.020
regulation of cell differentiationGO:00455951420.020
carboxylic acid metabolic processGO:0019752220.020
response to woundingGO:00096111160.020
endocrine processGO:005088620.020
positive regulation of macromolecule metabolic processGO:0010604930.020
Human Mouse
protein polymerizationGO:005125840.020
catechol containing compound metabolic processGO:000971220.020
tyrosine phosphorylation of stat3 proteinGO:004250310.020
chordate embryonic developmentGO:00430092710.020
regulation of circadian rhythmGO:004275240.020
regulation of nucleoside metabolic processGO:000911820.020
head developmentGO:00603223030.020
regulation of establishment of protein localizationGO:007020140.020
cellular component disassemblyGO:002241110.019
positive regulation of cell activationGO:005086710.019
b cell mediated immunityGO:001972430.019
protein dephosphorylationGO:000647030.019
internal protein amino acid acetylationGO:000647520.019
antimicrobial humoral responseGO:001973020.019
organelle fusionGO:004828430.019
mononuclear cell proliferationGO:003294310.019
response to hydrogen peroxideGO:004254230.019
leukocyte proliferationGO:007066110.019
immune responseGO:0006955280.019
macromolecule localizationGO:0033036540.019
small molecule catabolic processGO:004428230.019
cytokinesisGO:000091030.019
actin filament based movementGO:003004810.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
organelle organizationGO:00069962270.018
cell agingGO:000756920.018
homeostatic processGO:00425921420.018
Mouse
dicarboxylic acid transportGO:000683510.018
microtubule based processGO:0007017600.018
regulation of erk1 and erk2 cascadeGO:007037240.018
vesicle localizationGO:0051648270.018
cellular nitrogen compound metabolic processGO:00346412900.018
Human
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.018
rna transportGO:005065820.018
cognitionGO:005089010.018
small molecule metabolic processGO:0044281770.018
single organism nuclear importGO:190259330.017
response to bacteriumGO:0009617580.017
reactive oxygen species biosynthetic processGO:190340910.017
regulation of cell activationGO:005086510.017
positive regulation of cell cycleGO:004578730.017
regulation of programmed cell deathGO:00430671010.017
Mouse
organic substance transportGO:0071702580.017
regulation of immune responseGO:0050776140.017
microtubule organizing center organizationGO:003102310.017
gene expressionGO:00104672520.017
Human Mouse
regulation of inflammatory responseGO:005072720.017
regionalizationGO:00030022740.017
axon developmentGO:00615641660.017
Zebrafish
double strand break repairGO:000630230.017
positive regulation of secretion by cellGO:190353210.017
regulation of apoptotic processGO:0042981980.017
Mouse
regulation of reproductive processGO:200024140.017
wound healingGO:0042060900.017
regulation of intracellular protein transportGO:003315730.017
cell proliferationGO:0008283800.017
regulation of cytokine productionGO:000181730.017
system processGO:00030081850.017
positive regulation of immune responseGO:0050778110.017
tissue regenerationGO:0042246740.016
peptide metabolic processGO:000651810.016
regulation of gene expressionGO:00104682650.016
Human Mouse
regulation of response to cytokine stimulusGO:006075930.016
embryonic limb morphogenesisGO:003032620.016
actin filament polymerizationGO:003004120.016
nuclear exportGO:005116810.016
regulation of endocrine processGO:004406020.016
synaptic vesicle localizationGO:009747910.016
nucleocytoplasmic transportGO:000691340.016
organic cyclic compound biosynthetic processGO:19013622230.016
Human
regulation of cardiac muscle tissue developmentGO:005502410.016
nitric oxide metabolic processGO:004620920.016
protein import into nucleusGO:000660630.016
regulation of defense responseGO:0031347140.016
regulation of innate immune responseGO:0045088110.016
multi organism processGO:00517041340.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
negative regulation of response to cytokine stimulusGO:006076120.016
regulation of myotube differentiationGO:001083020.016
response to amino acidGO:004320020.016
cell killingGO:000190620.016
response to oxygen containing compoundGO:1901700550.015
nucleic acid transportGO:005065720.015
regulation of cytokine mediated signaling pathwayGO:000195930.015
response to corticosteroidGO:003196010.015
protein importGO:001703830.015
positive regulation of response to stimulusGO:0048584800.015
developmental growth involved in morphogenesisGO:0060560860.015
dna biosynthetic processGO:007189730.015
centrosome organizationGO:005129710.015
response to nicotineGO:003509420.015
cellular nitrogen compound biosynthetic processGO:00442712180.015
Human
mitotic cell cycle processGO:1903047480.015
cytoskeleton dependent cytokinesisGO:006164030.015
cellular response to organic substanceGO:00713101050.015
positive regulation of signalingGO:0023056560.015
locomotor rhythmGO:004547530.015
organic acid metabolic processGO:0006082310.015
regulation of protein transportGO:005122330.015
synaptic vesicle transportGO:004848910.015
intracellular transportGO:0046907320.015
cellular aromatic compound metabolic processGO:00067252950.015
Human
positive regulation of protein complex assemblyGO:003133420.015
guanosine containing compound metabolic processGO:190106840.015
nucleobase containing compound transportGO:001593120.015
nucleobase containing compound biosynthetic processGO:00346542050.015
Human
spermatid developmentGO:000728620.015
response to nutrientGO:000758430.014
establishment of rna localizationGO:005123630.014
mitotic cell cycleGO:0000278640.014
circadian sleep wake cycle sleepGO:005080210.014
behaviorGO:0007610740.014
protein acetylationGO:000647320.014
microtubule based movementGO:0007018330.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
Human
wnt signaling pathwayGO:0016055800.014
positive regulation of map kinase activityGO:004340630.014
nitric oxide biosynthetic processGO:000680920.014
hormone secretionGO:004687920.014
anterior posterior pattern specificationGO:00099521520.014
internal peptidyl lysine acetylationGO:001839320.014
regulation of circadian sleep wake cycleGO:004274910.014
positive regulation of cellular amine metabolic processGO:003324000.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
Human
negative regulation of immune responseGO:005077720.014
regulation of cell developmentGO:00602841000.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
regulation of protein ubiquitinationGO:003139630.014
regulation of gtpase activityGO:004308720.014
regulation of tube sizeGO:003515020.014
protein localizationGO:0008104400.014
establishment of vesicle localizationGO:0051650240.014
regulation of protein localization to nucleusGO:190018020.014
cellular monovalent inorganic cation homeostasisGO:003000420.014
reactive oxygen species metabolic processGO:007259360.014
ameboidal type cell migrationGO:00016671430.014
nuclear importGO:005117030.014
development of primary female sexual characteristicsGO:004654540.013
monoamine transportGO:001584410.013
regulation of synaptic plasticityGO:004816710.013
organelle localizationGO:0051640490.013
establishment of synaptic vesicle localizationGO:009748010.013
regulation of synapse assemblyGO:005196330.013
regulation of intracellular phGO:005145310.013
regulation of neurotransmitter transportGO:005158810.013
positive regulation of jnk cascadeGO:004633030.013
embryonic heart tube developmentGO:00350501330.013
meiotic chromosome segregationGO:004513230.013
regulation of cellular biosynthetic processGO:00313262450.013
Human
histone h3 k4 methylationGO:005156820.013
mitotic cytokinesisGO:000028130.013
skin developmentGO:0043588540.013
ion transmembrane transportGO:0034220910.013
inorganic ion transmembrane transportGO:0098660570.013
protein acylationGO:004354330.013
cation transmembrane transportGO:0098655650.013
lysosomal transportGO:000704120.013
antibacterial humoral responseGO:001973120.013
indole containing compound metabolic processGO:004243020.013
macromolecule biosynthetic processGO:00090592270.013
Human
protein targeting to nucleusGO:004474430.013
chemosensory behaviorGO:000763510.013
negative regulation of innate immune responseGO:004582420.013
regulation of blood vessel sizeGO:005088020.013
mitotic dna damage checkpointGO:004477340.013
protein localization to nucleusGO:003450430.013
defense response to fungusGO:005083220.013
peptidyl serine phosphorylationGO:001810510.013
stem cell maintenanceGO:001982740.012
hormone transportGO:000991420.012
peptide transportGO:001583310.012
organelle assemblyGO:00709251100.012
guanosine containing compound catabolic processGO:190106920.012
blood vessel morphogenesisGO:00485142160.012
pigment cell differentiationGO:0050931380.012
eye developmentGO:00016542770.012
regulation of primary metabolic processGO:00800903110.012
Human Mouse
mesoderm developmentGO:0007498880.012
positive regulation of multi organism processGO:004390230.012
regulation of macromolecule biosynthetic processGO:00105562250.012
Human
response to endogenous stimulusGO:0009719830.012
regulation of embryonic developmentGO:0045995470.012
immune system developmentGO:00025201910.012
regulation of cytoplasmic transportGO:190364940.012
nucleic acid templated transcriptionGO:00976591810.012
Human
transcription dna templatedGO:00063511810.012
Human
regulation of protein targetingGO:190353320.012
cortical cytoskeleton organizationGO:003086510.012
regulation of response to biotic stimulusGO:000283120.011
macromolecular complex disassemblyGO:003298410.011
immune system processGO:00023762410.011
Mouse
positive regulation of metabolic processGO:00098931080.011
Human Mouse
inositol lipid mediated signalingGO:004801720.011
positive regulation of muscle organ developmentGO:004863610.011
ovulation cycleGO:004269820.011
embryonic organ morphogenesisGO:00485622740.011
positive regulation of striated muscle cell differentiationGO:005115510.011
heart developmentGO:00075073130.011
circadian sleep wake cycleGO:004274520.011
endocrine hormone secretionGO:006098620.011
epithelial cell morphogenesisGO:000338220.011
regulation of cell deathGO:00109411030.011
Mouse
gtp metabolic processGO:004603940.011
regulation of nucleotide catabolic processGO:003081120.011
regulation of organ growthGO:004662030.011
regulation of phosphate metabolic processGO:0019220430.011
Mouse
neuron neuron synaptic transmissionGO:000727010.011
response to inorganic substanceGO:0010035380.011
regulation of blood coagulationGO:003019310.011
negative regulation of cell communicationGO:0010648960.011
Mouse
positive regulation of cytoskeleton organizationGO:005149530.011
sensory organ developmentGO:00074233930.011
jak stat cascadeGO:000725950.011
response to glucoseGO:000974930.011
negative regulation of apoptotic processGO:0043066550.011
Mouse
collagen metabolic processGO:003296320.011
positive regulation of striated muscle tissue developmentGO:004584410.011
cellular macromolecule biosynthetic processGO:00346452240.011
Human
regulation of cellular protein metabolic processGO:0032268520.011
Mouse
extrinsic apoptotic signaling pathwayGO:009719130.011
negative regulation of defense responseGO:003134820.011
organophosphate biosynthetic processGO:0090407230.011
immune effector processGO:0002252230.011
positive regulation of biosynthetic processGO:0009891680.011
Human
regulation of neurotransmitter secretionGO:004692810.011
response to glucocorticoidGO:005138410.011
cation homeostasisGO:0055080330.011
negative regulation of multi organism processGO:004390130.011
positive regulation of signal transductionGO:0009967560.011
response to carbohydrateGO:000974330.011
mitotic dna integrity checkpointGO:004477440.011
regulation of protein polymerizationGO:003227120.011
microtubule cytoskeleton organizationGO:0000226330.010
myeloid cell developmentGO:0061515320.010
ovulation cycle processGO:002260220.010
regulation of rho protein signal transductionGO:003502320.010
sequestering of metal ionGO:005123830.010
negative regulation of catabolic processGO:000989530.010
ras protein signal transductionGO:000726570.010
primary neural tube formationGO:001402010.010
negative regulation of cellular metabolic processGO:0031324770.010
regulation of circadian sleep wake cycle sleepGO:004518710.010
specification of symmetryGO:00097992040.010
regulation of localizationGO:00328791040.010
tissue remodelingGO:004877140.010
nitrogen compound transportGO:0071705230.010
cellular component assembly involved in morphogenesisGO:00109271070.010
regulation of protein import into nucleusGO:004230620.010
response to vitaminGO:003327330.010
detection of chemical stimulusGO:000959340.010

ikbkg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.090
disease of anatomical entityDOID:700.090
Human
hematopoietic system diseaseDOID:7400.029
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
nervous system diseaseDOID:86300.016
musculoskeletal system diseaseDOID:1700.014
organ system cancerDOID:005068600.012
disease of metabolismDOID:001466700.011