Danio rerio

50 known processes

araf

v-raf murine sarcoma 3611 viral oncogene homolog

(Aliases: wu:fk45h07,zgc:92074)

araf biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.074
larval developmentGO:000216420.072
morphogenesis of an epitheliumGO:00020093330.071
immune system developmentGO:00025201910.069
maintenance of locationGO:005123540.068
immune system processGO:00023762410.062
phagocytosisGO:000690930.059
negative regulation of biological processGO:00485193040.056
tube morphogenesisGO:00352393490.054
nitrogen compound metabolic processGO:00068073190.053
cellular nitrogen compound metabolic processGO:00346412900.052
organic cyclic compound metabolic processGO:19013603010.051
cell projection morphogenesisGO:00488582440.049
regulation of metabolic processGO:00192223590.049
stem cell maintenanceGO:001982740.047
convergent extensionGO:00600261180.047
response to carbohydrateGO:000974330.045
gastrulationGO:00073692080.044
cellular macromolecule metabolic processGO:00442603910.044
generation of neuronsGO:00486993850.044
signal transductionGO:00071654550.044
cellular response to external stimulusGO:007149620.042
cellular protein catabolic processGO:004425740.041
regulation of protein catabolic processGO:004217610.041
protein metabolic processGO:00195381830.041
digestive tract developmentGO:00485652650.040
agingGO:000756820.040
digestive system developmentGO:00551232890.040
cellular protein metabolic processGO:00442671290.039
regionalizationGO:00030022740.039
heterocycle metabolic processGO:00464832900.039
biosynthetic processGO:00090582940.038
positive regulation of cellular component biogenesisGO:004408930.038
hematopoietic or lymphoid organ developmentGO:00485341910.038
protein polymerizationGO:005125840.037
positive regulation of stress activated mapk cascadeGO:003287430.037
organelle organizationGO:00069962270.037
gene expressionGO:00104672520.036
central nervous system developmentGO:00074173870.036
regulation of epithelial cell proliferationGO:005067830.036
regulation of cellular biosynthetic processGO:00313262450.036
single organism metabolic processGO:00447102170.036
regulation of cellular metabolic processGO:00313233200.036
cell surface receptor signaling pathwayGO:00071663250.036
cellular macromolecule biosynthetic processGO:00346452240.035
positive regulation of cellular catabolic processGO:003133130.035
modification dependent protein catabolic processGO:001994130.035
regulation of signal transductionGO:00099662250.035
cell part morphogenesisGO:00329902460.035
single organism transportGO:00447652060.035
regulation of nitrogen compound metabolic processGO:00511712510.035
autophagyGO:000691440.035
neuron projection developmentGO:00311751800.034
response to external stimulusGO:00096052640.034
neuron differentiationGO:00301823530.034
proteolysis involved in cellular protein catabolic processGO:005160330.034
cytokinesisGO:000091030.034
regulation of signalingGO:00230512350.034
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.034
meiotic nuclear divisionGO:000712640.034
determination of bilateral symmetryGO:00098552040.033
wnt signaling pathwayGO:0016055800.033
convergent extension involved in gastrulationGO:0060027710.033
regulation of biological qualityGO:00650082630.033
chordate embryonic developmentGO:00430092710.033
positive regulation of cell cycleGO:004578730.033
positive regulation of catabolic processGO:000989640.033
response to stressGO:00069502630.033
regulation of cytokine productionGO:000181730.032
nucleocytoplasmic transportGO:000691340.032
neuron developmentGO:00486662620.032
cell morphogenesisGO:00009022890.032
regulation of primary metabolic processGO:00800903110.032
proteasomal protein catabolic processGO:001049820.032
nuclear transportGO:005116940.031
regulation of gene expressionGO:00104682650.031
brain developmentGO:00074202930.031
nucleobase containing compound metabolic processGO:00061392740.031
organic substance biosynthetic processGO:19015762890.031
protein targeting to nucleusGO:004474430.031
ubiquitin dependent protein catabolic processGO:000651130.031
positive regulation of transportGO:005105020.031
regulation of protein complex assemblyGO:004325430.030
establishment of protein localization to organelleGO:007259440.030
multicellular organism growthGO:003526440.030
protein import into nucleusGO:000660630.030
stem cell proliferationGO:007208940.030
membrane invaginationGO:001032410.030
positive regulation of map kinase activityGO:004340630.030
regulation of cellular amine metabolic processGO:003323800.030
rna metabolic processGO:00160702190.030
amine metabolic processGO:000930820.029
single organism localizationGO:19025782250.029
organelle fusionGO:004828430.029
regulation of intracellular protein transportGO:003315730.029
response to chemicalGO:00422213200.029
heterocycle biosynthetic processGO:00181302150.029
cellular component morphogenesisGO:00329893360.029
regulation of macromolecule metabolic processGO:00602553170.029
single organism organelle organizationGO:19025891990.029
lipid storageGO:001991510.028
cellular ketone metabolic processGO:0042180110.028
protein modification processGO:00362111000.028
nucleic acid metabolic processGO:00903042440.028
guanosine containing compound catabolic processGO:190106920.028
stem cell divisionGO:001714510.028
regulation of sequestering of calcium ionGO:005128240.028
regulation of cellular amino acid metabolic processGO:000652100.028
thrombocyte differentiationGO:000257440.028
cell morphogenesis involved in differentiationGO:00009041950.027
nuclear importGO:005117030.027
cell projection organizationGO:00300302840.027
regulation of protein ubiquitinationGO:003139630.027
wnt signaling pathway involved in digestive tract morphogenesisGO:004433340.027
protein importGO:001703830.027
regulation of dendrite developmentGO:005077330.027
sequestering of metal ionGO:005123830.027
cortical cytoskeleton organizationGO:003086510.026
cellular aromatic compound metabolic processGO:00067252950.026
transportGO:00068102200.026
adherens junction organizationGO:003433240.026
regulation of protein modification by small protein conjugation or removalGO:190332030.026
regulation of biosynthetic processGO:00098892500.026
hemopoiesisGO:00300971830.026
single organism nuclear importGO:190259330.026
determination of dorsal ventral asymmetryGO:0048262340.026
response to uvGO:000941130.025
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.025
regulation of peptidyl tyrosine phosphorylationGO:005073010.025
macromolecule biosynthetic processGO:00090592270.025
head developmentGO:00603223030.025
melanin metabolic processGO:000658220.025
negative regulation of catabolic processGO:000989530.025
secondary metabolic processGO:001974830.025
developmental growthGO:00485891660.025
cellular response to lipopolysaccharideGO:007122230.025
regulation of autophagyGO:001050630.025
dorsal ventral pattern formationGO:00099531250.024
establishment of localizationGO:00512342440.024
cellular component disassemblyGO:002241110.024
positive regulation of canonical wnt signaling pathwayGO:009026340.024
growthGO:00400071740.024
i kappab kinase nf kappab signalingGO:000724940.024
gtp catabolic processGO:000618420.024
somatic stem cell maintenanceGO:003501910.024
embryonic heart tube developmentGO:00350501330.024
transcription dna templatedGO:00063511810.024
cellular amine metabolic processGO:004410620.024
aromatic compound biosynthetic processGO:00194382170.024
regulation of multicellular organism growthGO:004001440.024
positive regulation of cellular processGO:00485222010.024
sequestering of calcium ionGO:005120830.024
single organism membrane fusionGO:004480120.024
mitotic cell cycleGO:0000278640.023
positive regulation of jnk cascadeGO:004633030.023
response to organic substanceGO:00100331530.023
phagocytosis engulfmentGO:000691110.023
regulation of multicellular organismal developmentGO:20000262230.023
negative regulation of nuclear divisionGO:005178430.023
cellular response to biotic stimulusGO:007121630.023
regulation of cellular ketone metabolic processGO:001056570.023
somite developmentGO:0061053960.023
protein localization to nucleusGO:003450430.023
cognitionGO:005089010.023
positive regulation of biological processGO:00485182530.023
negative regulation of protein phosphorylationGO:000193340.023
cellular response to chemical stimulusGO:00708871570.023
cell cycleGO:0007049930.023
localization of cellGO:00516742440.023
regulation of response to stimulusGO:00485832690.023
apoptotic processGO:00069151160.023
regulation of dna replicationGO:000627530.023
organic acid metabolic processGO:0006082310.023
regulation of multicellular organismal processGO:00512392770.023
modification dependent macromolecule catabolic processGO:004363230.023
positive regulation of protein complex assemblyGO:003133420.022
extrinsic apoptotic signaling pathwayGO:009719130.022
locomotionGO:00400113130.022
embryonic organ developmentGO:00485683810.022
release of sequestered calcium ion into cytosolGO:005120930.022
positive regulation of neuron apoptotic processGO:004352510.022
cellular amino acid metabolic processGO:000652070.022
cellular protein modification processGO:00064641000.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
nucleobase containing compound biosynthetic processGO:00346542050.022
specification of symmetryGO:00097992040.022
regulation of synapse organizationGO:005080730.022
regulation of protein import into nucleusGO:004230620.022
germ line stem cell maintenanceGO:003071820.022
canonical wnt signaling pathwayGO:0060070480.021
actin filament polymerizationGO:003004120.021
positive regulation of cytosolic calcium ion concentrationGO:000720440.021
regulation of rna biosynthetic processGO:20011412130.021
guanosine containing compound metabolic processGO:190106840.021
heart developmentGO:00075073130.021
actin polymerization or depolymerizationGO:000815420.021
cell migrationGO:00164772370.021
regulation of protein targetingGO:190353320.021
cellular response to organic substanceGO:00713101050.021
oxoacid metabolic processGO:0043436310.021
organonitrogen compound metabolic processGO:1901564740.021
calcium ion transport into cytosolGO:006040230.021
somitogenesisGO:0001756870.021
cell deathGO:00082191210.021
tube closureGO:006060610.021
organic cyclic compound biosynthetic processGO:19013622230.021
synaptic growth at neuromuscular junctionGO:005112420.021
gtp metabolic processGO:004603940.021
digestive tract morphogenesisGO:00485462310.021
response to abiotic stimulusGO:00096281220.021
sensory organ developmentGO:00074233930.020
regulation of cell deathGO:00109411030.020
regulation of protein transportGO:005122330.020
cellular response to starvationGO:000926710.020
regulation of cytoplasmic transportGO:190364940.020
regulation of nucleocytoplasmic transportGO:004682220.020
single fertilizationGO:000733830.020
regulation of i kappab kinase nf kappab signalingGO:004312240.020
negative regulation of signalingGO:0023057960.020
positive regulation of cytokine productionGO:000181920.020
cellular response to molecule of bacterial originGO:007121930.020
neuroblast proliferationGO:000740520.020
cell substrate adhesionGO:003158940.020
nuclear migrationGO:000709730.020
positive regulation of cellular amine metabolic processGO:003324000.020
cellular component biogenesisGO:00440851780.020
activation of mapk activityGO:000018730.020
cortical actin cytoskeleton organizationGO:003086610.020
macromolecule modificationGO:00434121110.019
segmentationGO:0035282970.019
carboxylic acid metabolic processGO:0019752220.019
carbohydrate homeostasisGO:003350010.019
developmental growth involved in morphogenesisGO:0060560860.019
regulation of macromolecule biosynthetic processGO:00105562250.019
liver developmentGO:0001889960.019
regulation of cell projection assemblyGO:006049140.019
response to alkaloidGO:004327920.019
axon developmentGO:00615641660.019
epithelial cell proliferation involved in liver morphogenesisGO:007257520.019
cytoskeleton organizationGO:0007010960.019
wound healingGO:0042060900.019
mitochondrion organizationGO:000700540.019
female sex differentiationGO:004666040.019
positive regulation of immune effector processGO:000269930.019
cell motilityGO:00488702440.019
exocytosisGO:000688710.019
regulation of establishment of protein localizationGO:007020140.019
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.019
regulation of cell communicationGO:00106462320.019
negative regulation of response to stimulusGO:00485851040.019
regulation of dendrite morphogenesisGO:004881430.018
negative regulation of kinase activityGO:003367340.018
small molecule metabolic processGO:0044281770.018
anterior posterior pattern specificationGO:00099521520.018
hepaticobiliary system developmentGO:0061008980.018
peptide transportGO:001583310.018
metal ion transportGO:0030001580.018
positive regulation of cytoskeleton organizationGO:005149530.018
skeletal system developmentGO:00015011810.018
embryonic organ morphogenesisGO:00485622740.018
negative regulation of protein serine threonine kinase activityGO:007190120.018
regulation of protein polymerizationGO:003227120.018
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.018
fertilizationGO:000956630.018
cell morphogenesis involved in neuron differentiationGO:00486671630.018
regulation of cell shapeGO:000836010.018
membrane fusionGO:006102520.018
negative regulation of protein kinase activityGO:000646940.017
golgi vesicle transportGO:004819330.017
cellular response to nutrient levelsGO:003166920.017
cellular biosynthetic processGO:00442492860.017
female gonad developmentGO:000858540.017
negative regulation of sequestering of calcium ionGO:005128340.017
negative regulation of mitosisGO:004583930.017
regulation of apoptotic processGO:0042981980.017
primary neural tube formationGO:001402010.017
cell migration involved in gastrulationGO:0042074790.017
sensory organ morphogenesisGO:00905962000.017
regulation of programmed cell deathGO:00430671010.017
positive regulation of cell divisionGO:005178120.017
negative regulation of cellular catabolic processGO:003133030.017
regulation of mrna processingGO:005068430.017
cellular carbohydrate metabolic processGO:004426240.017
peptidyl serine modificationGO:001820920.017
neuron projection morphogenesisGO:00488121610.017
cellular nitrogen compound biosynthetic processGO:00442712180.017
cytosolic calcium ion transportGO:006040130.017
phosphorus metabolic processGO:00067931090.017
lamellipodium assemblyGO:003003210.017
homeostatic processGO:00425921420.017
rna biosynthetic processGO:00327741810.017
regulation of protein localization to nucleusGO:190018020.017
eye developmentGO:00016542770.016
regulation of developmental processGO:00507932470.016
development of primary female sexual characteristicsGO:004654540.016
regulation of cell activationGO:005086510.016
lamellipodium organizationGO:009758110.016
blood vessel developmentGO:00015682460.016
intracellular signal transductionGO:0035556850.016
endosomal transportGO:001619720.016
negative regulation of signal transductionGO:0009968940.016
protein dephosphorylationGO:000647030.016
response to external biotic stimulusGO:0043207970.016
cellular component assemblyGO:00226071700.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
regulation of reactive oxygen species metabolic processGO:200037720.016
regulation of cellular protein catabolic processGO:190336210.016
cellular amide metabolic processGO:004360340.016
regulation of nucleic acid templated transcriptionGO:19035062130.016
regulation of purine nucleotide catabolic processGO:003312120.016
nucleic acid templated transcriptionGO:00976591810.016
negative regulation of protein localization to nucleusGO:190018120.016
positive regulation of epithelial cell proliferationGO:005067910.015
cell matrix adhesionGO:000716040.015
meiotic cell cycle processGO:190304630.015
cellular response to extracellular stimulusGO:003166820.015
vasculature developmentGO:00019442780.015
regulation of jun kinase activityGO:004350630.015
pancreas developmentGO:0031016840.015
xenobiotic metabolic processGO:000680540.015
programmed cell deathGO:00125011190.015
response to corticosteroidGO:003196010.015
response to transition metal nanoparticleGO:1990267280.015
sensory system developmentGO:0048880760.015
embryo development ending in birth or egg hatchingGO:00097922710.015
response to drugGO:004249330.015
stem cell differentiationGO:00488631170.015
negative regulation of epithelial cell proliferationGO:005068010.015
regulation of mrna splicing via spliceosomeGO:004802430.015
hepatocyte proliferationGO:007257420.015
regulation of nucleobase containing compound metabolic processGO:00192192500.015
organelle localizationGO:0051640490.015
cellular response to stressGO:0033554620.015
response to woundingGO:00096111160.015
positive regulation of i kappab kinase nf kappab signalingGO:004312330.015
axonogenesisGO:00074091520.015
phosphate containing compound metabolic processGO:00067961080.015
neurotransmitter transportGO:000683620.015
negative regulation of cytoplasmic transportGO:190365020.015
lateral line developmentGO:0048882660.015
microtubule based processGO:0007017600.015
negative regulation of cellular processGO:00485232830.015
protein complex localizationGO:003150310.015
positive regulation of neuron deathGO:190121610.015
protein acetylationGO:000647320.015
protein localization to plasma membraneGO:007265910.014
mesenchyme developmentGO:00604851270.014
heart loopingGO:0001947940.014
negative regulation of intracellular protein transportGO:009031730.014
negative regulation of cell communicationGO:0010648960.014
ameboidal type cell migrationGO:00016671430.014
regulation of exocytosisGO:001715710.014
negative regulation of cytokine productionGO:000181810.014
negative regulation of nucleocytoplasmic transportGO:004682320.014
regulation of filopodium assemblyGO:005148920.014
regulation of reproductive processGO:200024140.014
cellular localizationGO:0051641970.014
regulation of protein metabolic processGO:0051246560.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
protein acylationGO:004354330.014
ion transportGO:00068111140.014
gland developmentGO:00487321430.014
cellular component movementGO:00069283350.014
regulation of transcription dna templatedGO:00063552130.014
system processGO:00030081850.014
pronuclear migrationGO:003504610.014
b cell differentiationGO:003018310.014
cellular response to oxygen levelsGO:007145310.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
alpha amino acid metabolic processGO:190160530.014
protein heterooligomerizationGO:005129110.014
developmental cell growthGO:0048588520.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
tissue remodelingGO:004877140.013
epithelial tube morphogenesisGO:00605621480.013
somatic muscle developmentGO:000752540.013
regulation of nucleoside metabolic processGO:000911820.013
positive regulation of secretionGO:005104710.013
response to glucocorticoidGO:005138410.013
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathwayGO:002200210.013
regulation of cellular component organizationGO:0051128860.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
protein polyubiquitinationGO:000020940.013
hormone transportGO:000991420.013
g1 s transition of mitotic cell cycleGO:000008210.013
dicarboxylic acid transportGO:000683510.013
regulation of inflammatory responseGO:005072720.013
regulation of anterior head developmentGO:200074220.013
regulation of jak stat cascadeGO:004642530.013
regulation of synaptic plasticityGO:004816710.013
leukocyte proliferationGO:007066110.013
hormone secretionGO:004687920.013
deathGO:00162651210.013
nucleoside monophosphate catabolic processGO:000912540.013
regulation of wnt signaling pathway involved in digestive tract morphogenesisGO:200005620.013
alternative mrna splicing via spliceosomeGO:000038010.013
regulation of metal ion transportGO:001095940.013
regulation of nucleotide catabolic processGO:003081120.013
regulation of synapse assemblyGO:005196330.013
regulation of cell differentiationGO:00455951420.013
meiotic chromosome segregationGO:004513230.013
positive regulation of dna metabolic processGO:005105410.013
mediolateral intercalationGO:006003130.013
g2 m transition of mitotic cell cycleGO:000008640.013
mesenchymal cell differentiationGO:0048762870.013
spermatid developmentGO:000728620.013
positive regulation of epithelial cell differentiationGO:003085820.013
regulation of alternative mrna splicing via spliceosomeGO:000038110.013
regulation of gtp catabolic processGO:003312420.013
peptidyl serine phosphorylationGO:001810510.013
optic placode formationGO:000174340.013
regulation of cell developmentGO:00602841000.013
positive regulation of secretion by cellGO:190353210.013
adult behaviorGO:003053420.013
erk1 and erk2 cascadeGO:007037140.013
positive regulation of jun kinase activityGO:004350720.013
negative regulation of defense responseGO:003134820.013
retina development in camera type eyeGO:00600411460.013
non canonical wnt signaling pathwayGO:0035567130.013
post embryonic organ developmentGO:004856940.013
negative regulation of intracellular transportGO:003238730.013
response to metal ionGO:0010038340.013
purine ribonucleoside monophosphate catabolic processGO:000916940.012
regulation of bindingGO:005109830.012
regulation of cell morphogenesis involved in differentiationGO:0010769380.012
cellular response to radiationGO:007147840.012
cartilage developmentGO:0051216960.012
angiogenesisGO:00015251580.012
female meiotic divisionGO:000714320.012
regulation of rna metabolic processGO:00512522240.012
negative regulation of immune responseGO:005077720.012
determination of left right symmetryGO:00073681790.012
cytoskeleton dependent cytokinesisGO:006164030.012
response to nutrientGO:000758430.012
multi organism processGO:00517041340.012
sensory perception of chemical stimulusGO:000760630.012
regulation of carbohydrate metabolic processGO:000610940.012
regulation of cell matrix adhesionGO:000195210.012
rna localizationGO:000640340.012
embryonic heart tube morphogenesisGO:00031431080.012
response to inorganic substanceGO:0010035380.012
positive regulation of gtpase activityGO:004354710.012
camera type eye morphogenesisGO:00485931080.012
regulation of molecular functionGO:0065009700.012
regulation of stem cell differentiationGO:200073640.012
positive regulation of nucleoside metabolic processGO:004597910.012
regulation of nervous system developmentGO:0051960900.012
spindle assemblyGO:005122520.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
hepatic duct developmentGO:006101120.012
spermatid differentiationGO:004851520.012
cytokinetic processGO:003250620.012
connective tissue developmentGO:0061448990.012
regulation of chromosome segregationGO:005198310.012
inner ear developmentGO:00488391260.012
actin cytoskeleton organizationGO:0030036630.012
cell projection assemblyGO:0030031640.012
lateral line system developmentGO:0048925760.012
spindle assembly involved in mitosisGO:009030710.012
lipid homeostasisGO:005508830.011
regulation of wnt signaling pathway calcium modulating pathwayGO:000859130.011
response to hexoseGO:000974630.011
response to monosaccharideGO:003428430.011
macromolecular complex disassemblyGO:003298410.011
regulation of neuron differentiationGO:0045664560.011
negative regulation of mapk cascadeGO:004340940.011
camera type eye developmentGO:00430102220.011
enzyme linked receptor protein signaling pathwayGO:00071671060.011
mononuclear cell proliferationGO:003294310.011
macroautophagyGO:001623610.011
response to glucoseGO:000974930.011
neuron projection extensionGO:1990138450.011
embryonic limb morphogenesisGO:003032620.011
heart morphogenesisGO:00030071560.011
regulation of cardiac muscle tissue developmentGO:005502410.011
myeloid cell differentiationGO:0030099860.011
determination of heart left right asymmetryGO:00613711170.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
positive regulation of nucleotide catabolic processGO:003081310.011
optic placode formation involved in camera type eye formationGO:004661930.011
negative regulation of chromosome organizationGO:200125110.011
microtubule organizing center organizationGO:003102310.011
mesenchymal cell developmentGO:0014031780.011
synaptic transmission cholinergicGO:000727140.011
ear developmentGO:00435831270.011
regulation of cellular protein metabolic processGO:0032268520.011
ribosomal small subunit biogenesisGO:004227420.011
dorsal convergenceGO:0060030140.011
response to other organismGO:0051707970.011

araf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
inherited metabolic disorderDOID:65500.019
disease of metabolismDOID:001466700.019
nervous system diseaseDOID:86300.016
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
musculoskeletal system diseaseDOID:1700.013