Danio rerio

0 known processes

pnp4a

purine nucleoside phosphorylase 4a

(Aliases: zgc:86889)

pnp4a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleobase containing compound biosynthetic processGO:00346542050.589
Mouse
xanthophore differentiationGO:005093630.453
cellular biosynthetic processGO:00442492860.406
Mouse
pigmentationGO:0043473850.292
regulation of retina development in camera type eyeGO:190286620.274
cellular nitrogen compound biosynthetic processGO:00442712180.268
Mouse
pigment cell differentiationGO:0050931380.262
nucleobase containing compound metabolic processGO:00061392740.256
Mouse
leukocyte proliferationGO:007066110.230
Mouse
positive regulation of tyrosine phosphorylation of stat3 proteinGO:004251710.207
dopamine metabolic processGO:004241720.193
dopamine biosynthetic processGO:004241620.184
melanocyte differentiationGO:0030318260.166
developmental pigmentationGO:0048066480.159
embryonic organ morphogenesisGO:00485622740.157
catechol containing compound metabolic processGO:000971220.137
regulation of neural retina developmentGO:006107420.136
tube morphogenesisGO:00352393490.119
response to chemicalGO:00422213200.111
camera type eye developmentGO:00430102220.111
regulation of developmental pigmentationGO:004807060.109
mesenchymal cell developmentGO:0014031780.109
cellular component morphogenesisGO:00329893360.105
heterocycle biosynthetic processGO:00181302150.104
Mouse
mesenchymal cell differentiationGO:0048762870.100
regulation of histone methylationGO:003106030.100
maintenance of locationGO:005123540.098
generation of neuronsGO:00486993850.090
cellular nitrogen compound metabolic processGO:00346412900.090
Mouse
embryonic organ developmentGO:00485683810.087
nitrogen compound metabolic processGO:00068073190.084
Mouse
cell cell junction maintenanceGO:004521710.083
organic cyclic compound metabolic processGO:19013603010.080
Mouse
mesenchyme developmentGO:00604851270.079
negative regulation of programmed cell deathGO:0043069580.079
Mouse
cellular amine metabolic processGO:004410620.073
regulation of synaptic plasticityGO:004816710.069
pigment granule organizationGO:004875340.067
skeletal system developmentGO:00015011810.067
cellular component movementGO:00069283350.065
chordate embryonic developmentGO:00430092710.065
agingGO:000756820.065
digestive system developmentGO:00551232890.063
positive regulation of biological processGO:00485182530.061
Mouse
central nervous system neuron differentiationGO:0021953740.060
catecholamine metabolic processGO:000658420.056
positive regulation of chromosome organizationGO:200125210.055
sensory organ developmentGO:00074233930.054
cellular macromolecule metabolic processGO:00442603910.054
Mouse
regulation of cell differentiationGO:00455951420.053
Mouse
embryonic skeletal system developmentGO:0048706970.053
spinal cord developmentGO:0021510460.051
neuroepithelial cell differentiationGO:0060563260.051
catechol containing compound biosynthetic processGO:000971320.051
organic substance biosynthetic processGO:19015762890.051
Mouse
aromatic compound biosynthetic processGO:00194382170.050
Mouse
neuron differentiationGO:00301823530.050
regulation of response to stimulusGO:00485832690.050
Mouse
positive regulation of myeloid cell differentiationGO:004563920.050
melanocyte migrationGO:009732440.049
rna biosynthetic processGO:00327741810.048
periodic partitioningGO:000736510.047
rna metabolic processGO:00160702190.046
positive regulation of erk1 and erk2 cascadeGO:007037420.045
macrophage chemotaxisGO:004824630.045
biosynthetic processGO:00090582940.045
Mouse
eye developmentGO:00016542770.045
positive regulation of histone modificationGO:003105810.044
nuclear importGO:005117030.043
single organism metabolic processGO:00447102170.041
Mouse
small molecule metabolic processGO:0044281770.040
Mouse
brain developmentGO:00074202930.040
positive regulation of macrophage chemotaxisGO:001075910.039
central nervous system developmentGO:00074173870.039
catecholamine biosynthetic processGO:004242320.039
regulation of nitrogen compound metabolic processGO:00511712510.038
Mouse
phenol containing compound biosynthetic processGO:004618940.036
digestive tract developmentGO:00485652650.036
aromatic amino acid family metabolic processGO:000907210.035
cell differentiation in spinal cordGO:0021515400.035
signal transductionGO:00071654550.035
Mouse
organonitrogen compound metabolic processGO:1901564740.034
Mouse
larval developmentGO:000216420.034
phosphate containing compound metabolic processGO:00067961080.033
Mouse
cell morphogenesisGO:00009022890.031
programmed cell deathGO:00125011190.031
Mouse
regulation of rna metabolic processGO:00512522240.031
transcription dna templatedGO:00063511810.031
negative regulation of apoptotic processGO:0043066550.030
Mouse
osteoclast developmentGO:003603510.030
cell proliferationGO:0008283800.029
Mouse
spermatid differentiationGO:004851520.029
enzyme linked receptor protein signaling pathwayGO:00071671060.029
cellular aromatic compound metabolic processGO:00067252950.029
Mouse
extrinsic apoptotic signaling pathwayGO:009719130.028
response to organic substanceGO:00100331530.027
melanosome organizationGO:003243840.027
embryonic skeletal system morphogenesisGO:0048704930.026
regulation of programmed cell deathGO:00430671010.026
Mouse
organonitrogen compound biosynthetic processGO:1901566470.026
Mouse
carboxylic acid metabolic processGO:0019752220.025
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.025
organic cyclic compound biosynthetic processGO:19013622230.025
Mouse
single organism biosynthetic processGO:0044711710.025
Mouse
positive regulation of chromatin modificationGO:190331010.024
regulation of transcription dna templatedGO:00063552130.024
segment polarity determinationGO:000736710.024
cell deathGO:00082191210.024
Mouse
retina development in camera type eyeGO:00600411460.024
neural crest cell differentiationGO:0014033720.024
regulation of multicellular organismal developmentGO:20000262230.023
Mouse
microglia differentiationGO:001400410.023
regulation of developmental processGO:00507932470.023
Mouse
positive regulation of cellular amino acid metabolic processGO:004576400.023
regulation of cell deathGO:00109411030.023
Mouse
positive regulation of retina development in camera type eyeGO:190286810.023
stem cell differentiationGO:00488631170.023
anterior posterior pattern specificationGO:00099521520.023
regulation of macromolecule biosynthetic processGO:00105562250.022
regulation of anatomical structure morphogenesisGO:00226031300.022
cell motilityGO:00488702440.022
cation transportGO:0006812810.022
neuron developmentGO:00486662620.020
cellular macromolecule biosynthetic processGO:00346452240.020
mononuclear cell migrationGO:007167410.020
regulation of gene expressionGO:00104682650.020
negative regulation of cell communicationGO:0010648960.019
determination of heart left right asymmetryGO:00613711170.019
g2 m transition of mitotic cell cycleGO:000008640.019
smooth muscle contractionGO:000693920.019
cellular amino acid metabolic processGO:000652070.019
regulation of bindingGO:005109830.019
regulation of cell shapeGO:000836010.019
positive regulation of leukocyte differentiationGO:190210710.018
Mouse
intracellular signal transductionGO:0035556850.018
Mouse
regulation of cell fate commitmentGO:0010453220.018
proteasomal protein catabolic processGO:001049820.018
cell morphogenesis involved in differentiationGO:00009041950.018
transcription from rna polymerase ii promoterGO:0006366800.018
regulation of calcium ion transportGO:005192420.018
venous endothelial cell migration involved in lymph vessel developmentGO:006085540.018
establishment of protein localization to organelleGO:007259440.018
regulation of mapk cascadeGO:0043408140.017
regulation of signalingGO:00230512350.017
regulation of tyrosine phosphorylation of stat proteinGO:004250910.017
organism emergence from protective structureGO:007168440.017
response to lipidGO:0033993600.016
cell substrate junction assemblyGO:000704420.016
tyrosine metabolic processGO:000657010.016
cellular response to organic substanceGO:00713101050.016
b cell activationGO:004211320.016
Mouse
regulation of macrophage chemotaxisGO:001075810.016
response to woundingGO:00096111160.016
single organism localizationGO:19025782250.016
regulation of cell developmentGO:00602841000.016
transportGO:00068102200.016
spermatid developmentGO:000728620.016
nucleic acid templated transcriptionGO:00976591810.015
alpha amino acid metabolic processGO:190160530.015
gland developmentGO:00487321430.015
positive regulation of transportGO:005105020.015
pigment biosynthetic processGO:004614890.015
localization of cellGO:00516742440.015
synaptic target recognitionGO:000803910.015
phagocytosisGO:000690930.015
mitotic dna damage checkpointGO:004477340.015
regulation of jak stat cascadeGO:004642530.015
positive regulation of catabolic processGO:000989640.015
locomotionGO:00400113130.014
Worm
mononuclear cell proliferationGO:003294310.014
Mouse
regulation of cell activationGO:005086510.014
Mouse
muscle organ developmentGO:00075171010.014
response to stressGO:00069502630.014
Mouse Worm
regulation of signal transductionGO:00099662250.014
taxisGO:00423301090.014
positive regulation of myeloid leukocyte differentiationGO:000276310.014
regulation of transcription from rna polymerase ii promoterGO:00063571140.014
purine nucleotide biosynthetic processGO:0006164200.014
Mouse
regulation of organelle assemblyGO:190211540.014
muscle tissue developmentGO:00605371100.014
positive regulation of leukocyte chemotaxisGO:000269010.014
regulation of mononuclear cell migrationGO:007167510.014
heart morphogenesisGO:00030071560.014
regulation of neural precursor cell proliferationGO:200017730.014
developmental programmed cell deathGO:001062340.014
protein metabolic processGO:00195381830.014
positive regulation of metabolic processGO:00098931080.013
Mouse
gene expressionGO:00104672520.013
macromolecule modificationGO:00434121110.013
response to organic cyclic compoundGO:0014070510.013
cellular protein catabolic processGO:004425740.013
notochord developmentGO:0030903540.013
negative regulation of sequestering of calcium ionGO:005128340.013
sequestering of calcium ionGO:005120830.013
muscle structure developmentGO:00610611960.013
fat soluble vitamin metabolic processGO:000677540.013
organic acid metabolic processGO:0006082310.013
Mouse
lens fiber cell morphogenesisGO:007030930.013
regulation of protein bindingGO:004339330.013
regionalizationGO:00030022740.013
melanin metabolic processGO:000658220.013
single organism reproductive processGO:0044702400.013
cell fate commitmentGO:0045165990.013
secondary metabolic processGO:001974830.013
cytokine production involved in immune responseGO:000236710.013
glial cell differentiationGO:0010001420.013
ion transmembrane transportGO:0034220910.013
cellular response to lipidGO:0071396390.012
epithelial cell differentiationGO:00308551160.012
regulation of cellular ketone metabolic processGO:001056570.012
positive regulation of cellular processGO:00485222010.012
Mouse
positive regulation of cellular metabolic processGO:0031325940.012
Mouse
melanin biosynthetic processGO:004243810.012
cell fate specificationGO:0001708680.012
mitotic dna integrity checkpointGO:004477440.012
lymphocyte proliferationGO:004665110.012
Mouse
erk1 and erk2 cascadeGO:007037140.012
regulation of pigment cell differentiationGO:005093220.012
amine metabolic processGO:000930820.012
myeloid cell differentiationGO:0030099860.012
regulation of cellular metabolic processGO:00313233200.012
Mouse
gtp catabolic processGO:000618420.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
cartilage developmentGO:0051216960.012
osteoclast differentiationGO:003031610.012
phagosome maturationGO:009038210.012
carbon dioxide transportGO:001567030.012
intra s dna damage checkpointGO:003157310.012
protein alkylationGO:0008213130.012
negative regulation of dna metabolic processGO:005105340.011
regulation of cellular amino acid metabolic processGO:000652100.011
immune system developmentGO:00025201910.011
Mouse
positive regulation of ras protein signal transductionGO:004657910.011
positive regulation of jak stat cascadeGO:004642720.011
phosphorylationGO:0016310690.011
regulation of metabolic processGO:00192223590.011
Mouse
protein targeting to nucleusGO:004474430.011
oxoacid metabolic processGO:0043436310.011
regulation of bone mineralizationGO:003050020.011
sequestering of metal ionGO:005123830.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.011
heart developmentGO:00075073130.011
protein importGO:001703830.011
protein localization to nucleusGO:003450430.011
axon ensheathment in central nervous systemGO:003229120.011
regulation of cellular amine metabolic processGO:003323800.010
regulation of tyrosine phosphorylation of stat3 proteinGO:004251610.010
trabecula formationGO:006034320.010
central nervous system myelinationGO:002201020.010
activation of mapk activityGO:000018730.010
lens fiber cell developmentGO:007030730.010
negative regulation of multicellular organismal processGO:0051241690.010
somitogenesisGO:0001756870.010
regulation of melanocyte differentiationGO:004563420.010
positive regulation of nucleotide catabolic processGO:003081310.010
chromatin organizationGO:0006325220.010

pnp4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.075
disease of anatomical entityDOID:700.075
disease of cellular proliferationDOID:1456600.064
cancerDOID:16200.064
organ system cancerDOID:005068600.029
hematopoietic system diseaseDOID:7400.021
musculoskeletal system cancerDOID:006010000.021
sensory system diseaseDOID:005015500.021
nervous system diseaseDOID:86300.021
nonsyndromic deafnessDOID:005056300.021
auditory system diseaseDOID:274200.021