Danio rerio

0 known processes

ddr2b

discoidin domain receptor family, member 2b

(Aliases: ddr2,si:ch211-193c2.1)

ddr2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cognitionGO:005089010.131
larval developmentGO:000216420.108
positive regulation of cellular component biogenesisGO:004408930.102
cellular response to lipopolysaccharideGO:007122230.096
positive regulation of protein complex assemblyGO:003133420.095
mononuclear cell proliferationGO:003294310.088
stem cell maintenanceGO:001982740.084
morphogenesis of an epitheliumGO:00020093330.075
regulation of cytokine productionGO:000181730.075
regulation of metabolic processGO:00192223590.074
positive regulation of cell cycleGO:004578730.074
cilium movement involved in cell motilityGO:006029430.072
convergent extension involved in gastrulationGO:0060027710.070
leukocyte proliferationGO:007066110.067
positive regulation of canonical wnt signaling pathwayGO:009026340.066
multicellular organism growthGO:003526440.066
negative regulation of biological processGO:00485193040.065
maintenance of locationGO:005123540.063
signal transductionGO:00071654550.061
positive regulation of cell activationGO:005086710.061
regulation of cell projection assemblyGO:006049140.060
protein localization to nucleusGO:003450430.059
convergent extensionGO:00600261180.058
cellular nitrogen compound metabolic processGO:00346412900.057
immune system processGO:00023762410.057
response to drugGO:004249330.057
rna metabolic processGO:00160702190.056
regulation of organelle assemblyGO:190211540.056
lymphocyte proliferationGO:004665110.055
regulation of synapse organizationGO:005080730.055
regulation of cell activationGO:005086510.054
cellular amine metabolic processGO:004410620.053
regulation of cellular ketone metabolic processGO:001056570.053
gene expressionGO:00104672520.052
regulation of extrinsic apoptotic signaling pathwayGO:200123630.051
positive regulation of transportGO:005105020.051
cell surface receptor signaling pathwayGO:00071663250.051
regulation of macromolecule metabolic processGO:00602553170.050
organic substance biosynthetic processGO:19015762890.049
agingGO:000756820.048
regulation of cellular amine metabolic processGO:003323800.048
positive regulation of erk1 and erk2 cascadeGO:007037420.048
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.048
regulation of carbohydrate metabolic processGO:000610940.048
endosomal transportGO:001619720.048
b cell activationGO:004211320.048
positive regulation of cytokine productionGO:000181920.047
response to virusGO:0009615210.047
extrinsic apoptotic signaling pathwayGO:009719130.046
tissue remodelingGO:004877140.046
actin polymerization or depolymerizationGO:000815420.046
regulation of signalingGO:00230512350.046
positive regulation of cell adhesionGO:004578510.046
organic cyclic compound metabolic processGO:19013603010.045
regionalizationGO:00030022740.045
regulation of cell shapeGO:000836010.045
erk1 and erk2 cascadeGO:007037140.045
female sex differentiationGO:004666040.044
cellular response to biotic stimulusGO:007121630.044
regulation of peptidyl tyrosine phosphorylationGO:005073010.044
adherens junction organizationGO:003433240.044
amine metabolic processGO:000930820.044
pigment granule transportGO:0051904190.044
chemosensory behaviorGO:000763510.043
negative regulation of kinase activityGO:003367340.043
negative regulation of protein phosphorylationGO:000193340.043
peptidyl serine phosphorylationGO:001810510.042
regulation of primary metabolic processGO:00800903110.042
response to other organismGO:0051707970.042
cellular ketone metabolic processGO:0042180110.042
response to carbohydrateGO:000974330.042
response to hexoseGO:000974630.042
aromatic compound biosynthetic processGO:00194382170.041
immune system developmentGO:00025201910.041
response to corticosteroidGO:003196010.041
regulation of gene expressionGO:00104682650.040
b cell differentiationGO:003018310.040
cellular response to molecule of bacterial originGO:007121930.040
regulation of erk1 and erk2 cascadeGO:007037240.040
negative regulation of synapse assemblyGO:005196420.040
positive regulation of protein kinase b signalingGO:005189710.040
heterocycle metabolic processGO:00464832900.039
regulation of cellular amino acid metabolic processGO:000652100.039
regulation of response to nutrient levelsGO:003210710.039
cell substrate adhesionGO:003158940.039
hemopoiesisGO:00300971830.039
regulation of multicellular organism growthGO:004001440.038
cellular macromolecule metabolic processGO:00442603910.038
regulation of signal transductionGO:00099662250.038
organic acid metabolic processGO:0006082310.038
regulation of establishment of protein localizationGO:007020140.038
nucleocytoplasmic transportGO:000691340.038
digestive system developmentGO:00551232890.037
cellular component morphogenesisGO:00329893360.037
peptidyl serine modificationGO:001820920.037
cellular amino acid metabolic processGO:000652070.037
alpha amino acid metabolic processGO:190160530.037
cellular modified amino acid metabolic processGO:000657530.037
negative regulation of protein kinase activityGO:000646940.037
response to stressGO:00069502630.037
phagocytosisGO:000690930.037
positive regulation of jnk cascadeGO:004633030.036
positive regulation of cell killingGO:003134320.036
regulation of nitrogen compound metabolic processGO:00511712510.036
enzyme linked receptor protein signaling pathwayGO:00071671060.036
female gonad developmentGO:000858540.036
regulation of biological qualityGO:00650082630.036
sensory perception of chemical stimulusGO:000760630.035
nitrogen compound metabolic processGO:00068073190.035
regulation of cellular carbohydrate metabolic processGO:001067540.035
nucleobase containing compound metabolic processGO:00061392740.035
localization of cellGO:00516742440.035
regulation of synapse assemblyGO:005196330.035
cellular response to oxygen levelsGO:007145310.035
stem cell differentiationGO:00488631170.034
nucleic acid metabolic processGO:00903042440.034
regulation of biosynthetic processGO:00098892500.034
modification dependent macromolecule catabolic processGO:004363230.034
sex determinationGO:000753010.034
positive regulation of map kinase activityGO:004340630.033
response to biotic stimulusGO:0009607970.033
signal transduction in absence of ligandGO:003803410.033
protein secretionGO:000930610.033
positive regulation of cellular amine metabolic processGO:003324000.033
regulation of protein bindingGO:004339330.033
cellular component movementGO:00069283350.033
positive regulation of catabolic processGO:000989640.033
synaptic growth at neuromuscular junctionGO:005112420.032
specification of symmetryGO:00097992040.032
positive regulation of secretionGO:005104710.032
nuclear transportGO:005116940.032
regulation of synaptic growth at neuromuscular junctionGO:000858210.032
positive regulation of immune effector processGO:000269930.032
head developmentGO:00603223030.032
germ line stem cell maintenanceGO:003071820.032
myeloid cell differentiationGO:0030099860.031
regulation of cell communicationGO:00106462320.031
post embryonic organ developmentGO:004856940.031
regulation of protein complex assemblyGO:004325430.031
cilium movementGO:0003341260.031
biosynthetic processGO:00090582940.030
sensory perception of smellGO:000760820.030
hematopoietic or lymphoid organ developmentGO:00485341910.030
tyrosine phosphorylation of stat proteinGO:000726010.030
nucleobase containing compound biosynthetic processGO:00346542050.030
regulation of cell matrix adhesionGO:000195210.030
organelle organizationGO:00069962270.030
cytokinesisGO:000091030.030
development of primary female sexual characteristicsGO:004654540.030
digestive tract morphogenesisGO:00485462310.029
developmental growthGO:00485891660.029
proteolysis involved in cellular protein catabolic processGO:005160330.029
response to foodGO:003209410.029
negative regulation of protein serine threonine kinase activityGO:007190120.029
gland developmentGO:00487321430.029
spermatid differentiationGO:004851520.029
small molecule metabolic processGO:0044281770.029
cellular carbohydrate metabolic processGO:004426240.029
cell morphogenesisGO:00009022890.029
positive regulation of cytosolic calcium ion concentrationGO:000720440.029
ameboidal type cell migrationGO:00016671430.029
lipid storageGO:001991510.028
cell substrate junction assemblyGO:000704420.028
smooth muscle contractionGO:000693920.028
regulation of protein transportGO:005122330.028
regulation of cellular metabolic processGO:00313233200.028
locomotionGO:00400113130.028
modification dependent protein catabolic processGO:001994130.028
regulation of rna biosynthetic processGO:20011412130.028
cellular protein catabolic processGO:004425740.028
melanosome transportGO:0032402190.028
ovulation cycle processGO:002260220.028
response to chemicalGO:00422213200.028
production of molecular mediator of immune responseGO:000244020.027
regulation of leukocyte mediated immunityGO:000270310.027
oxoacid metabolic processGO:0043436310.027
regulation of response to stimulusGO:00485832690.027
somatic muscle developmentGO:000752540.027
negative regulation of mapk cascadeGO:004340940.027
heterocycle biosynthetic processGO:00181302150.027
cellular nitrogen compound biosynthetic processGO:00442712180.027
regulation of wound healingGO:006104120.027
negative regulation of macromolecule metabolic processGO:0010605760.027
intracellular signal transductionGO:0035556850.027
protein metabolic processGO:00195381830.027
regulation of multicellular organismal processGO:00512392770.027
positive regulation of biological processGO:00485182530.026
cell matrix adhesionGO:000716040.026
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.026
cellular protein metabolic processGO:00442671290.026
negative regulation of cellular processGO:00485232830.026
cellular macromolecule biosynthetic processGO:00346452240.026
cell motilityGO:00488702440.026
regulation of cellular macromolecule biosynthetic processGO:20001122220.026
nucleic acid templated transcriptionGO:00976591810.026
lipid metabolic processGO:0006629520.026
tube morphogenesisGO:00352393490.026
cellular biosynthetic processGO:00442492860.026
muscle cell migrationGO:001481240.026
oocyte maturationGO:000155640.026
cilium organizationGO:0044782710.025
negative regulation of sequestering of calcium ionGO:005128340.025
positive regulation of lipid metabolic processGO:004583410.025
cellular response to hormone stimulusGO:0032870390.025
cell part morphogenesisGO:00329902460.025
growthGO:00400071740.025
myeloid cell developmentGO:0061515320.025
positive regulation of cellular metabolic processGO:0031325940.025
periodic partitioningGO:000736510.025
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.025
regulation of tube sizeGO:003515020.024
rna biosynthetic processGO:00327741810.024
regulation of developmental processGO:00507932470.024
negative regulation of metabolic processGO:0009892860.024
regulation of multicellular organismal developmentGO:20000262230.024
regulation of response to extracellular stimulusGO:003210410.024
transcription dna templatedGO:00063511810.024
carboxylic acid metabolic processGO:0019752220.024
regulation of rna metabolic processGO:00512522240.024
positive regulation of cellular catabolic processGO:003133130.024
regulation of reactive oxygen species metabolic processGO:200037720.024
positive regulation of carbohydrate metabolic processGO:004591310.024
brain developmentGO:00074202930.024
cellular aromatic compound metabolic processGO:00067252950.024
regulation of blood pressureGO:000821710.024
guanosine containing compound metabolic processGO:190106840.023
epithelium migrationGO:0090132250.023
somatic stem cell maintenanceGO:003501910.023
protein targeting to nucleusGO:004474430.023
single organism metabolic processGO:00447102170.023
cell projection morphogenesisGO:00488582440.023
gtp metabolic processGO:004603940.023
protein homooligomerizationGO:005126030.023
positive regulation of epithelial cell migrationGO:001063420.023
negative regulation of wnt signaling pathwayGO:0030178300.023
adult behaviorGO:003053420.023
wnt signaling pathwayGO:0016055800.023
sequestering of metal ionGO:005123830.023
positive regulation of gtp catabolic processGO:003312610.023
single organism nuclear importGO:190259330.023
anterior posterior pattern specificationGO:00099521520.023
positive regulation of apoptotic signaling pathwayGO:200123510.023
maternal determination of anterior posterior axis embryoGO:000835840.023
regulation of nucleobase containing compound metabolic processGO:00192192500.023
positive regulation of stress activated mapk cascadeGO:003287430.022
regulation of nucleic acid templated transcriptionGO:19035062130.022
cell migrationGO:00164772370.022
regulation of blood vessel sizeGO:005088020.022
single organism transportGO:00447652060.022
gastrulationGO:00073692080.022
regulation of cytoplasmic transportGO:190364940.022
response to external biotic stimulusGO:0043207970.022
neuroblast proliferationGO:000740520.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
regulation of production of molecular mediator of immune responseGO:000270010.022
transportGO:00068102200.022
regulation of stem cell differentiationGO:200073640.022
regulation of natural killer cell mediated immunityGO:000271510.022
stem cell proliferationGO:007208940.022
compound eye developmentGO:004874920.022
organonitrogen compound metabolic processGO:1901564740.022
response to glucoseGO:000974930.022
cellular response to radiationGO:007147840.022
cellular component biogenesisGO:00440851780.022
nuclear importGO:005117030.021
negative regulation of response to stimulusGO:00485851040.021
determination of bilateral symmetryGO:00098552040.021
stem cell divisionGO:001714510.021
rna localizationGO:000640340.021
spermatid developmentGO:000728620.021
regulation of gtp catabolic processGO:003312420.021
response to monosaccharideGO:003428430.021
cilium or flagellum dependent cell motilityGO:000153940.021
regulation of jun kinase activityGO:004350630.021
osteoclast differentiationGO:003031610.021
positive regulation of cellular carbohydrate metabolic processGO:001067610.021
negative regulation of chemotaxisGO:005092240.021
macromolecule modificationGO:00434121110.021
establishment of protein localization to organelleGO:007259440.021
nonmotile primary cilium assemblyGO:003505820.021
response to woundingGO:00096111160.021
cellular response to hypoxiaGO:007145610.021
negative regulation of multicellular organismal processGO:0051241690.020
protein modification processGO:00362111000.020
protein acetylationGO:000647320.020
wound healingGO:0042060900.020
microtubule organizing center organizationGO:003102310.020
cellular protein modification processGO:00064641000.020
ovulation cycleGO:004269820.020
cellular response to organic substanceGO:00713101050.020
macromolecule biosynthetic processGO:00090592270.020
regulation of glial cell differentiationGO:004568540.020
cytoskeleton dependent cytokinesisGO:006164030.020
single organism organelle organizationGO:19025891990.020
regulation of mrna processingGO:005068430.020
locomotor rhythmGO:004547530.020
camera type eye developmentGO:00430102220.020
regulation of cell cell adhesionGO:0022407130.020
organic cyclic compound biosynthetic processGO:19013622230.020
mapk cascadeGO:0000165180.020
positive regulation of response to stimulusGO:0048584800.020
regulation of metal ion transportGO:001095940.020
generation of neuronsGO:00486993850.020
regulation of jak stat cascadeGO:004642530.019
phosphate containing compound metabolic processGO:00067961080.019
system processGO:00030081850.019
guanosine containing compound catabolic processGO:190106920.019
determination of left right symmetryGO:00073681790.019
protein importGO:001703830.019
regulation of inflammatory responseGO:005072720.019
tissue regenerationGO:0042246740.019
regulation of organ growthGO:004662030.019
superoxide metabolic processGO:000680120.019
positive regulation of nitrogen compound metabolic processGO:0051173690.019
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.019
single organism localizationGO:19025782250.019
regulation of cell migration involved in sprouting angiogenesisGO:009004930.019
cellular response to nutrient levelsGO:003166920.019
regulation of reproductive processGO:200024140.019
homeostatic processGO:00425921420.019
regulation of localizationGO:00328791040.019
meiotic nuclear divisionGO:000712640.018
response to organic substanceGO:00100331530.018
phosphorylationGO:0016310690.018
cellular component assemblyGO:00226071700.018
gtp catabolic processGO:000618420.018
positive regulation of synapse assemblyGO:005196510.018
response to external stimulusGO:00096052640.018
cell projection organizationGO:00300302840.018
activation of jun kinase activityGO:000725720.018
cellular response to external stimulusGO:007149620.018
regulation of alternative mrna splicing via spliceosomeGO:000038110.018
sensory organ developmentGO:00074233930.018
establishment of localizationGO:00512342440.018
response to bacteriumGO:0009617580.018
cellular response to decreased oxygen levelsGO:003629410.018
release of sequestered calcium ion into cytosolGO:005120930.018
anatomical structure homeostasisGO:0060249360.017
regulation of cellular biosynthetic processGO:00313262450.017
negative regulation of cell communicationGO:0010648960.017
negative regulation of cytokine productionGO:000181810.017
positive regulation of jun kinase activityGO:004350720.017
cell adhesion mediated by integrinGO:003362710.017
membrane invaginationGO:001032410.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.017
positive regulation of leukocyte mediated immunityGO:000270510.017
regulation of protein catabolic processGO:004217610.017
positive regulation of cytoskeleton organizationGO:005149530.017
double strand break repairGO:000630230.017
positive regulation of cell divisionGO:005178120.017
glial cell migrationGO:000834730.017
cellular response to extracellular stimulusGO:003166820.017
positive regulation of macromolecule metabolic processGO:0010604930.017
centrosome organizationGO:005129710.017
positive regulation of muscle cell differentiationGO:005114910.017
regulation of purine nucleotide catabolic processGO:003312120.017
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.017
protein import into nucleusGO:000660630.017
activation of mapk activityGO:000018730.017
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.017
somitogenesisGO:0001756870.017
regulation of nucleotide catabolic processGO:003081120.017
erythrocyte homeostasisGO:0034101550.017
regulation of transcription dna templatedGO:00063552130.017
eye developmentGO:00016542770.016
primary neural tube formationGO:001402010.016
bone remodelingGO:004684920.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.016
cell cycle g1 s phase transitionGO:004484310.016
protein phosphorylationGO:0006468470.016
gastrulation with mouth forming secondGO:0001702440.016
antimicrobial humoral responseGO:001973020.016
regulation of macromolecule biosynthetic processGO:00105562250.016
regulation of cell differentiationGO:00455951420.016
negative regulation of immune responseGO:005077720.016
regulation of meiotic cell cycleGO:005144510.016
negative chemotaxisGO:005091910.016
blood vessel morphogenesisGO:00485142160.016
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.016
alternative mrna splicing via spliceosomeGO:000038010.016
wnt signaling pathway planar cell polarity pathwayGO:006007140.016
determination of heart left right asymmetryGO:00613711170.016
neuron projection developmentGO:00311751800.016
regulation of apoptotic processGO:0042981980.016
positive regulation of signalingGO:0023056560.016
regulation of cellular component movementGO:0051270550.016
epithelial cell migrationGO:0010631250.016
sensory organ morphogenesisGO:00905962000.015
positive regulation of myeloid cell differentiationGO:004563920.015
segmentationGO:0035282970.015
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.015
negative regulation of catabolic processGO:000989530.015
negative regulation of myeloid cell differentiationGO:004563810.015
cellular response to starvationGO:000926710.015
lens fiber cell morphogenesisGO:007030930.015
negative regulation of gliogenesisGO:001401410.015
cardiac atrium developmentGO:000323040.015
cell cycle arrestGO:000705010.015
regulation of receptor activityGO:001046920.015
positive regulation of translationGO:004572710.015
synaptic target recognitionGO:000803910.015
ubiquitin dependent protein catabolic processGO:000651130.015
negative regulation of developmental processGO:0051093650.015
response to hydrogen peroxideGO:004254230.015
angiogenesisGO:00015251580.015
tube closureGO:006060610.015
negative regulation of epithelial cell proliferationGO:005068010.015
embryonic organ morphogenesisGO:00485622740.015
heart loopingGO:0001947940.015
multi organism processGO:00517041340.015
endoderm formationGO:0001706290.015
embryo development ending in birth or egg hatchingGO:00097922710.015
leukocyte homeostasisGO:000177620.015
myeloid leukocyte migrationGO:0097529120.015
neuron differentiationGO:00301823530.015
organelle assemblyGO:00709251100.015
regulation of cysteine type endopeptidase activityGO:2000116210.015
positive regulation of nucleoside metabolic processGO:004597910.015
response to nutrient levelsGO:0031667100.014
regulation of cytokine biosynthetic processGO:004203510.014
positive regulation of neuron deathGO:190121610.014
neuron developmentGO:00486662620.014
leukocyte mediated cytotoxicityGO:000190910.014
deathGO:00162651210.014
regulation of response to biotic stimulusGO:000283120.014
skeletal muscle organ developmentGO:0060538780.014
cilium morphogenesisGO:0060271850.014
inositol lipid mediated signalingGO:004801720.014
positive regulation of lymphocyte mediated immunityGO:000270810.014
regulation of dendrite developmentGO:005077330.014
regulation of mrna splicing via spliceosomeGO:004802430.014
regulation of glucose importGO:004632410.014
embryonic heart tube morphogenesisGO:00031431080.014
phagocytosis engulfmentGO:000691110.014
cellular response to chemical stimulusGO:00708871570.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
regulation of bindingGO:005109830.014
carbohydrate biosynthetic processGO:001605110.014
positive regulation of striated muscle cell differentiationGO:005115510.014
proximal distal pattern formationGO:000995410.014
meiotic cell cycle processGO:190304630.014
positive regulation of epithelial cell differentiationGO:003085820.014
positive regulation of jak stat cascadeGO:004642720.014
zymogen activationGO:003163830.014
i kappab kinase nf kappab signalingGO:000724940.014
negative regulation of nuclear divisionGO:005178430.014
lipid homeostasisGO:005508830.014
intracellular mrna localizationGO:000829810.014
digestive tract developmentGO:00485652650.014
cellular amide metabolic processGO:004360340.014
lamellipodium organizationGO:009758110.014
cell deathGO:00082191210.014
meiosis iGO:000712710.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
dorsal ventral pattern formationGO:00099531250.014
regulation of nucleoside metabolic processGO:000911820.014
vasculature developmentGO:00019442780.014
regulation of dna replicationGO:000627530.014
synaptic transmission cholinergicGO:000727140.014
phosphatidylinositol mediated signalingGO:004801520.014
multicellular organismal homeostasisGO:0048871290.014
positive regulation of mrna metabolic processGO:190331320.014
positive regulation of neuron apoptotic processGO:004352510.014
lateral inhibitionGO:004633110.014
negative regulation of signal transductionGO:0009968940.014
regulation of endothelial cell proliferationGO:000193610.014
phosphatidylinositol 3 kinase signalingGO:001406520.014
positive regulation of cellular processGO:00485222010.014
positive regulation of cell communicationGO:0010647560.014
regulation of gtpase activityGO:004308720.014
s adenosylmethionine metabolic processGO:004650010.014
negative regulation of dna metabolic processGO:005105340.014
liver developmentGO:0001889960.014
hepaticobiliary system developmentGO:0061008980.014
response to acidic phGO:001044720.014
positive regulation of gtpase activityGO:004354710.013
response to endogenous stimulusGO:0009719830.013
muscle structure developmentGO:00610611960.013
negative regulation of ras protein signal transductionGO:004658010.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.013
regulation of calcium ion transportGO:005192420.013
stem cell fate commitmentGO:004886510.013
regulation of cellular protein catabolic processGO:190336210.013

ddr2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
cancerDOID:16200.030
disease of cellular proliferationDOID:1456600.030
organ system cancerDOID:005068600.022
connective tissue diseaseDOID:6500.021
bone diseaseDOID:008000100.021
musculoskeletal system diseaseDOID:1700.021
immune system diseaseDOID:291400.018
nervous system diseaseDOID:86300.017
disease of metabolismDOID:001466700.017
bone development diseaseDOID:008000600.016
gastrointestinal system cancerDOID:311900.014