Danio rerio

0 known processes

sp7

Sp7 transcription factor

(Aliases: osx,osterix)

sp7 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chordate embryonic developmentGO:00430092710.771
regulation of cell cycleGO:0051726520.768
regulation of macromolecule metabolic processGO:00602553170.686
Human Zebrafish Mouse Worm
regulation of nitrogen compound metabolic processGO:00511712510.649
Human Zebrafish Mouse Worm
sensory organ developmentGO:00074233930.623
embryonic organ morphogenesisGO:00485622740.494
skeletal system developmentGO:00015011810.472
regulation of primary metabolic processGO:00800903110.463
Human Zebrafish Mouse Worm
nitrogen compound metabolic processGO:00068073190.462
Human Zebrafish Mouse Worm
regionalizationGO:00030022740.436
Zebrafish
regulation of biosynthetic processGO:00098892500.431
Human Zebrafish Mouse Worm
regulation of metabolic processGO:00192223590.424
Human Zebrafish Mouse Worm
cellular macromolecule metabolic processGO:00442603910.422
Human Zebrafish Mouse Worm
gene expressionGO:00104672520.406
Human Zebrafish Mouse Worm
regulation of developmental processGO:00507932470.377
Human
regulation of cellular macromolecule biosynthetic processGO:20001122220.362
Human Zebrafish Mouse Worm
cellular nitrogen compound biosynthetic processGO:00442712180.356
Human Zebrafish Mouse Worm
odontogenesis of dentin containing toothGO:004247510.351
medial fin developmentGO:0033338160.335
inner ear developmentGO:00488391260.298
organic cyclic compound biosynthetic processGO:19013622230.291
Human Zebrafish Mouse Worm
regulation of gene expressionGO:00104682650.277
Human Zebrafish Mouse Worm
regulation of transcription from rna polymerase ii promoterGO:00063571140.276
Human Mouse Worm
heterocycle metabolic processGO:00464832900.266
Human Zebrafish Mouse Worm
embryonic skeletal system developmentGO:0048706970.265
ketone biosynthetic processGO:004218120.259
macromolecule biosynthetic processGO:00090592270.259
Human Zebrafish Mouse Worm
cellular nitrogen compound metabolic processGO:00346412900.255
Human Zebrafish Mouse Worm
epithelial cell differentiationGO:00308551160.253
regulation of transcription involved in cell fate commitmentGO:006085010.251
organic substance biosynthetic processGO:19015762890.248
Human Zebrafish Mouse Worm
nucleic acid templated transcriptionGO:00976591810.244
Human Zebrafish Mouse Worm
aromatic compound biosynthetic processGO:00194382170.241
Human Zebrafish Mouse Worm
embryonic organ developmentGO:00485683810.228
Zebrafish
regulation of cellular biosynthetic processGO:00313262450.227
Human Zebrafish Mouse Worm
regulation of multicellular organismal processGO:00512392770.225
regulation of nucleobase containing compound metabolic processGO:00192192500.218
Human Zebrafish Mouse Worm
embryonic limb morphogenesisGO:003032620.217
cellular macromolecule biosynthetic processGO:00346452240.214
Human Zebrafish Mouse Worm
nucleobase containing compound biosynthetic processGO:00346542050.214
Human Zebrafish Mouse Worm
heart developmentGO:00075073130.201
cellular response to organic cyclic compoundGO:0071407380.193
central nervous system developmentGO:00074173870.190
Zebrafish
regulation of rna biosynthetic processGO:20011412130.190
Human Zebrafish Mouse Worm
stem cell proliferationGO:007208940.175
stem cell differentiationGO:00488631170.165
Human
regulation of chondrocyte differentiationGO:003233010.161
adenohypophysis developmentGO:0021984150.160
eye developmentGO:00016542770.159
closure of optic fissureGO:006138660.158
cellular aromatic compound metabolic processGO:00067252950.154
Human Zebrafish Mouse Worm
digestive system developmentGO:00551232890.149
Zebrafish
positive regulation of neural precursor cell proliferationGO:200017910.147
regulation of stem cell differentiationGO:200073640.140
Human
negative regulation of biosynthetic processGO:0009890550.133
hemopoiesisGO:00300971830.131
Human
homeostatic processGO:00425921420.129
negative regulation of nucleic acid templated transcriptionGO:1903507450.127
cartilage condensationGO:000150230.124
nucleobase containing compound metabolic processGO:00061392740.119
Human Zebrafish Mouse Worm
proteolysis involved in cellular protein catabolic processGO:005160330.111
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:1900094170.109
kupffer s vesicle developmentGO:0070121500.109
organic cyclic compound metabolic processGO:19013603010.108
Human Zebrafish Mouse Worm
heterocycle biosynthetic processGO:00181302150.108
Human Zebrafish Mouse Worm
neuron differentiationGO:00301823530.107
neuron developmentGO:00486662620.103
rna metabolic processGO:00160702190.103
Human Zebrafish Mouse Worm
camera type eye developmentGO:00430102220.100
negative regulation of cellular metabolic processGO:0031324770.100
regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:1901213150.100
medial fin morphogenesisGO:0035141140.100
negative regulation of macromolecule biosynthetic processGO:0010558480.094
foregut morphogenesisGO:000744040.093
stem cell divisionGO:001714510.091
bmp signaling pathway involved in heart developmentGO:0061312150.091
ear developmentGO:00435831270.090
growthGO:00400071740.089
regulation of cell differentiationGO:00455951420.088
Human
vestibular receptor cell differentiationGO:006011430.086
regulation of cellular metabolic processGO:00313233200.083
Human Zebrafish Mouse Worm
locomotionGO:00400113130.083
Worm
morphogenesis of an epitheliumGO:00020093330.083
cell fate specificationGO:0001708680.080
cellular component morphogenesisGO:00329893360.079
regulation of signal transductionGO:00099662250.077
alcohol biosynthetic processGO:004616520.076
negative regulation of nucleobase containing compound metabolic processGO:0045934590.076
neuroblast proliferationGO:000740520.074
stem cell maintenanceGO:001982740.072
regulation of rna metabolic processGO:00512522240.070
Human Zebrafish Mouse Worm
embryonic skeletal joint morphogenesisGO:006027230.069
ectodermal placode formationGO:0060788260.068
negative regulation of cellular biosynthetic processGO:0031327550.067
embryonic skeletal joint developmentGO:007249830.066
transportGO:00068102200.065
Worm
cranial suture morphogenesisGO:006036310.065
embryonic camera type eye morphogenesisGO:0048596190.063
cell proliferationGO:0008283800.063
regulation of programmed cell deathGO:00430671010.063
Worm
negative regulation of metabolic processGO:0009892860.062
cellular biosynthetic processGO:00442492860.062
Human Zebrafish Mouse Worm
cellular response to chemical stimulusGO:00708871570.060
regulation of multicellular organism growthGO:004001440.060
biosynthetic processGO:00090582940.060
Human Zebrafish Mouse Worm
regulation of cell developmentGO:00602841000.058
skeletal system morphogenesisGO:00487051020.058
regulation of molecular functionGO:0065009700.057
astrocyte differentiationGO:004870810.057
negative regulation of gene expressionGO:0010629650.055
positive regulation of muscle organ developmentGO:004863610.055
positive regulation of cell cycleGO:004578730.054
columnar cuboidal epithelial cell differentiationGO:0002065380.053
somitogenesisGO:0001756870.053
gabaergic neuron differentiationGO:009715420.052
regulation of apoptotic processGO:0042981980.052
Worm
rna biosynthetic processGO:00327741810.051
Human Zebrafish Mouse Worm
cell deathGO:00082191210.051
Worm
regulation of multicellular organismal developmentGO:20000262230.050
cell part morphogenesisGO:00329902460.049
bmp signaling pathway involved in heart joggingGO:0003303140.049
developmental maturationGO:0021700340.049
sensory organ morphogenesisGO:00905962000.048
positive regulation of cellular processGO:00485222010.048
Human Worm
embryonic camera type eye developmentGO:0031076290.048
chondrocyte developmentGO:000206340.047
negative regulation of muscle cell differentiationGO:005114810.047
auditory receptor cell fate commitmentGO:000991240.047
negative regulation of transcription dna templatedGO:0045892450.047
otic vesicle morphogenesisGO:0071600340.046
embryonic hemopoiesisGO:0035162530.046
regulation of mesodermal cell fate specificationGO:004266190.046
deathGO:00162651210.045
Worm
skeletal muscle tissue developmentGO:0007519670.045
regulation of protein ubiquitinationGO:003139630.045
single organism nuclear importGO:190259330.044
bmp signaling pathwayGO:0030509520.043
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.043
signal transductionGO:00071654550.043
Zebrafish
cellular response to hormone stimulusGO:0032870390.042
connective tissue developmentGO:0061448990.041
determination of ventral identityGO:0048264210.040
negative regulation of nitrogen compound metabolic processGO:0051172590.040
positive regulation of stem cell proliferationGO:200064810.039
regulation of protein modification by small protein conjugation or removalGO:190332030.039
response to foodGO:003209410.038
liver developmentGO:0001889960.037
eye morphogenesisGO:00485921440.036
muscle tissue developmentGO:00605371100.036
response to hormoneGO:0009725480.036
heart loopingGO:0001947940.036
regulation of epithelial to mesenchymal transitionGO:001071730.035
regulation of response to stimulusGO:00485832690.035
cellular response to organic substanceGO:00713101050.035
negative regulation of cellular processGO:00485232830.035
neural tube patterningGO:0021532330.035
apoptotic processGO:00069151160.035
Worm
embryonic skeletal system morphogenesisGO:0048704930.035
regulation of cell deathGO:00109411030.034
Worm
response to woundingGO:00096111160.034
endocrine system developmentGO:0035270650.034
nucleic acid metabolic processGO:00903042440.034
Human Zebrafish Mouse Worm
establishment of protein localization to organelleGO:007259440.033
negative regulation of biological processGO:00485193040.033
determination of bilateral symmetryGO:00098552040.033
transcription from rna polymerase ii promoterGO:0006366800.033
Human Mouse Worm
single organism localizationGO:19025782250.032
embryonic pattern specificationGO:0009880440.032
regulation of establishment of protein localizationGO:007020140.032
inner ear receptor cell differentiationGO:0060113290.032
regulation of macromolecule biosynthetic processGO:00105562250.032
Human Zebrafish Mouse Worm
c21 steroid hormone biosynthetic processGO:000670010.031
transcription dna templatedGO:00063511810.031
Human Zebrafish Mouse Worm
negative regulation of striated muscle tissue developmentGO:004584320.031
positive regulation of transportGO:005105020.030
regulation of signalingGO:00230512350.029
pancreas developmentGO:0031016840.029
single organism metabolic processGO:00447102170.028
regulation of neural precursor cell proliferationGO:200017730.028
embryonic neurocranium morphogenesisGO:0048702150.028
wound healingGO:0042060900.028
regulation of bmp signaling pathway involved in heart joggingGO:2000223120.027
larval developmentGO:000216420.027
Worm
positive regulation of cellular metabolic processGO:0031325940.027
Human Worm
protein importGO:001703830.027
regulation of reproductive processGO:200024140.027
cellular response to hypoxiaGO:007145610.027
positive regulation of biological processGO:00485182530.027
Human Worm
homeostasis of number of cellsGO:0048872620.026
cardiac muscle cell developmentGO:0055013200.026
regulation of cellular protein catabolic processGO:190336210.026
tissue regenerationGO:0042246740.026
bone developmentGO:0060348140.026
mesenchymal cell proliferationGO:001046310.026
phosphate containing compound metabolic processGO:00067961080.026
head developmentGO:00603223030.025
Zebrafish
positive regulation of metabolic processGO:00098931080.025
Human Worm
negative regulation of striated muscle cell differentiationGO:005115410.025
chemosensory behaviorGO:000763510.024
negative regulation of rna metabolic processGO:0051253480.024
cellular ketone metabolic processGO:0042180110.024
multicellular organism growthGO:003526440.023
response to stressGO:00069502630.023
olfactory lobe developmentGO:002198840.022
muscle cell differentiationGO:00426921390.022
semicircular canal formationGO:006087640.022
response to oxygen containing compoundGO:1901700550.021
blood circulationGO:0008015870.021
regulation of wnt signaling pathway involved in heart developmentGO:000330720.021
midbrain developmentGO:0030901280.021
glandular epithelial cell differentiationGO:000206790.021
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.021
negative regulation of cell differentiationGO:0045596460.021
negative regulation of apoptotic processGO:0043066550.021
negative regulation of macromolecule metabolic processGO:0010605760.021
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.021
collagen biosynthetic processGO:003296420.020
epithelial cell morphogenesisGO:000338220.020
signal transduction in absence of ligandGO:003803410.020
organism emergence from protective structureGO:007168440.020
developmental growthGO:00485891660.020
regulation of biomineral tissue developmentGO:007016720.020
positive regulation of muscle tissue developmentGO:190186310.020
muscle fiber developmentGO:0048747520.020
regulation of nervous system developmentGO:0051960900.020
epidermis developmentGO:0008544480.020
endochondral bone morphogenesisGO:006035080.020
cellular protein catabolic processGO:004425740.020
cortisol metabolic processGO:003465020.020
regulation of cellular amine metabolic processGO:003323800.020
germ line stem cell maintenanceGO:003071820.020
regulation of cartilage developmentGO:006103570.019
gtp catabolic processGO:000618420.019
regulation of cellular protein metabolic processGO:0032268520.019
lipid biosynthetic processGO:0008610220.019
ear morphogenesisGO:0042471640.019
regulation of system processGO:0044057400.019
cell morphogenesis involved in differentiationGO:00009041950.019
pigmentationGO:0043473850.019
regulation of ion transportGO:0043269220.019
cortisol biosynthetic processGO:003465110.019
cellular response to steroid hormone stimulusGO:0071383310.019
positive regulation of transcription dna templatedGO:0045893570.019
Human Worm
positive regulation of nitrogen compound metabolic processGO:0051173690.018
Human Worm
regulation of phosphorylationGO:0042325260.018
appendage developmentGO:0048736800.018
cellular component movementGO:00069283350.018
positive regulation of macromolecule metabolic processGO:0010604930.018
Human Worm
extrinsic apoptotic signaling pathwayGO:009719130.018
lipid catabolic processGO:001604240.018
cell projection organizationGO:00300302840.018
retinal pigment epithelium developmentGO:000340680.018
neuron projection morphogenesisGO:00488121610.018
regulation of metal ion transportGO:001095940.018
positive regulation of nucleobase containing compound metabolic processGO:0045935690.018
Human Worm
tube morphogenesisGO:00352393490.018
Zebrafish
nuclear transportGO:005116940.017
inner ear receptor cell fate commitmentGO:006012040.017
chemical homeostasisGO:0048878490.017
pituitary gland developmentGO:0021983160.017
response to lipidGO:0033993600.017
cellular protein localizationGO:0034613200.017
positive regulation of rna biosynthetic processGO:1902680570.017
Human Worm
intracellular signal transductionGO:0035556850.017
glomerulus vasculature developmentGO:007201220.017
endodermal cell fate determinationGO:000749320.017
embryonic eye morphogenesisGO:0048048300.017
endocardial cushion morphogenesisGO:000320330.016
cell cycle processGO:0022402530.016
nuclear importGO:005117030.016
response to nicotineGO:003509420.016
regulation of anatomical structure morphogenesisGO:00226031300.016
heart processGO:0003015710.016
microtubule based processGO:0007017600.016
auditory receptor cell differentiationGO:0042491150.016
post embryonic organ developmentGO:004856940.016
protein localization to nucleusGO:003450430.016
modification dependent protein catabolic processGO:001994130.016
anterior commissure morphogenesisGO:002196030.016
activation of mapk activityGO:000018730.016
response to growth factorGO:0070848390.016
specification of organ identityGO:001009220.015
pronephric nephron tubule developmentGO:003902020.015
cardiocyte differentiationGO:0035051440.015
cell projection morphogenesisGO:00488582440.015
epithelial tube morphogenesisGO:00605621480.015
endocardial cushion formationGO:000327220.015
negative regulation of signalingGO:0023057960.015
t cell differentiationGO:003021760.015
cell motilityGO:00488702440.015
cellular localizationGO:0051641970.015
segmentationGO:0035282970.015
regulation of localizationGO:00328791040.015
hormone biosynthetic processGO:004244630.015
neural retina developmentGO:0003407490.015
positive regulation of cellular carbohydrate metabolic processGO:001067610.015
enteroendocrine cell differentiationGO:003588390.015
mesodermal cell fate specificationGO:0007501120.015
generation of neuronsGO:00486993850.015
regulation of protein transportGO:005122330.015
glucose homeostasisGO:004259310.014
response to abiotic stimulusGO:00096281220.014
modification dependent macromolecule catabolic processGO:004363230.014
negative regulation of dna replicationGO:000815620.014
pronephros developmentGO:0048793690.014
compound eye developmentGO:004874920.014
microtubule polymerization or depolymerizationGO:003110930.014
negative regulation of wnt signaling pathway involved in heart developmentGO:000330820.014
digestive tract developmentGO:00485652650.014
Zebrafish
positive regulation of catabolic processGO:000989640.014
response to endogenous stimulusGO:0009719830.014
regulation of tube sizeGO:003515020.014
muscle organ developmentGO:00075171010.014
response to vitaminGO:003327330.014
mechanoreceptor differentiationGO:0042490370.014
positive regulation of striated muscle tissue developmentGO:004584410.014
regulation of biological qualityGO:00650082630.014
anal fin morphogenesisGO:003514410.014
regulation of glial cell differentiationGO:004568540.014
myotube cell developmentGO:0014904350.014
nucleocytoplasmic transportGO:000691340.014
axon developmentGO:00615641660.013
trigeminal nerve developmentGO:002155930.013
exocrine pancreas developmentGO:0031017280.013
bone morphogenesisGO:0060349110.013
cell growthGO:0016049570.013
neurological system processGO:0050877620.013
bone remodelingGO:004684920.013
negative regulation of phosphorus metabolic processGO:0010563130.013
regulation of transportGO:0051049450.013
type b pancreatic cell developmentGO:000332340.013
regulation of meiotic cell cycleGO:005144510.013
monocarboxylic acid catabolic processGO:007232930.013
positive regulation of cellular catabolic processGO:003133130.013
negative regulation of oocyte developmentGO:006028320.013
negative regulation of endodermal cell fate specificationGO:004266480.013
regulation of cytoplasmic transportGO:190364940.013
apoptotic signaling pathwayGO:0097190230.013
cell maturationGO:0048469230.013
cell cycleGO:0007049930.013
protein stabilizationGO:005082120.013
fin developmentGO:0033333770.013
specification of symmetryGO:00097992040.013
regulation of oligodendrocyte differentiationGO:004871310.013
small molecule biosynthetic processGO:0044283160.013
positive regulation of secretionGO:005104710.012
cellular response to growth factor stimulusGO:0071363390.012
neuron projection developmentGO:00311751800.012
regulation of developmental growthGO:0048638380.012
single organism transportGO:00447652060.012
regulation of blood pressureGO:000821710.012
regulation of neurogenesisGO:0050767870.012
response to dexamethasoneGO:007154810.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.012
mechanosensory lateral line system developmentGO:0048881490.012
cellular protein modification processGO:00064641000.012
regulation of ion transmembrane transporter activityGO:003241220.012
muscle hypertrophyGO:001489620.012
hair cell differentiationGO:0035315320.012
tissue remodelingGO:004877140.012
auditory receptor cell fate specificationGO:004266720.012
small molecule metabolic processGO:0044281770.012
odontogenesisGO:004247690.012
regulation of cellular ketone metabolic processGO:001056570.012
negative regulation of catabolic processGO:000989530.012
response to organic cyclic compoundGO:0014070510.012
negative regulation of gastrulationGO:2000542110.011
cardiac muscle cell differentiationGO:0055007300.011
carboxylic acid metabolic processGO:0019752220.011
extracellular structure organizationGO:0043062270.011
regulation of protein metabolic processGO:0051246560.011
ubiquitin dependent protein catabolic processGO:000651130.011
embryonic cranial skeleton morphogenesisGO:0048701900.011
regulation of calcium ion transportGO:005192420.011
negative regulation of muscle tissue developmentGO:190186220.011
cell fate commitmentGO:0045165990.011
regulation of heart contractionGO:0008016320.011
regulation of multicellular organismal metabolic processGO:004424620.011
floor plate formationGO:0021508120.011
negative regulation of rna biosynthetic processGO:1902679450.011
positive regulation of multicellular organismal processGO:0051240520.011
rhombomere developmentGO:0021546190.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
positive regulation of mesenchymal cell proliferationGO:000205310.011
negative regulation of protein phosphorylationGO:000193340.011
mesenchyme developmentGO:00604851270.011
brain developmentGO:00074202930.011
Zebrafish
digestive tract morphogenesisGO:00485462310.011
Zebrafish
determination of heart left right asymmetryGO:00613711170.011
response to nutrientGO:000758430.011
embryonic digestive tract developmentGO:004856640.010
terpenoid catabolic processGO:001611520.010
regulation of catalytic activityGO:0050790550.010
inner ear morphogenesisGO:0042472630.010
determination of dorsal ventral asymmetryGO:0048262340.010
cell morphogenesisGO:00009022890.010
regulation of blood vessel sizeGO:005088020.010
peptide transportGO:001583310.010
system processGO:00030081850.010
regulation of cell maturationGO:190342910.010
fin regenerationGO:0031101510.010

sp7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone development diseaseDOID:008000600.888
Human
connective tissue diseaseDOID:6500.888
Human
disease of anatomical entityDOID:700.888
Human
bone diseaseDOID:008000100.888
Human
musculoskeletal system diseaseDOID:1700.888
Human
osteochondrodysplasiaDOID:225600.143
Human
dysostosisDOID:193400.048
nervous system diseaseDOID:86300.021
cardiovascular system diseaseDOID:128700.017
synostosisDOID:1197100.016
pfeiffer syndromeDOID:1470500.016
acrocephalosyndactyliaDOID:1296000.016
disease of metabolismDOID:001466700.013
physical disorderDOID:008001500.012
orofacial cleftDOID:005056700.012
atrioventricular septal defectDOID:005065100.010
heart diseaseDOID:11400.010
congenital heart diseaseDOID:168200.010
heart septal defectDOID:168100.010