IMP: Integrative Multi-species Prediction

Danio rerio

0 known processes

tnni2b.1

troponin I, skeletal, fast 2b.1

(Aliases: zgc:110715)

ZFIN: ZDB-GENE-050417-49
Entrez: 550249
Ensembl: ENSDARG00000035958
UniProtKB: Q567W1
UniProtKB: F1QCC0

Process Predictions
Disease Predictions

tnni2b.1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
atrial cardiac myofibril assembly	GO:0055004	2	0.233
myofibril assembly	GO:0030239	48	0.107
sarcomere organization	GO:0045214	26	0.080
ventricular cardiac myofibril assembly	GO:0055005	4	0.074
muscle cell development	GO:0055001	115	0.065
striated muscle tissue development	GO:0014706	110	0.061
heart development	GO:0007507	313	0.059
striated muscle cell differentiation	GO:0051146	129	0.055
muscle tissue development	GO:0060537	110	0.051
cellular component assembly involved in morphogenesis	GO:0010927	107	0.049
heart contraction	GO:0060047	71	0.047
organelle assembly	GO:0070925	110	0.039
cardiocyte differentiation	GO:0035051	44	0.038
regulation of protein polymerization	GO:0032271	2	0.038
positive regulation of blood circulation	GO:1903524	2	0.037
pronephros development	GO:0048793	69	0.032
endocardial cushion formation	GO:0003272	2	0.032
positive regulation of heart contraction	GO:0045823	2	0.031
morphogenesis of an epithelium	GO:0002009	333	0.031
cellular component morphogenesis	GO:0032989	336	0.030
regulation of protein complex assembly	GO:0043254	3	0.028
muscle structure development	GO:0061061	196	0.024
cellular component biogenesis	GO:0044085	178	0.024
lymphoid lineage cell migration into thymus	GO:0097535	4	0.023
endocardial cushion morphogenesis	GO:0003203	3	0.023
reactive nitrogen species metabolic process	GO:2001057	0	0.022
adult behavior	GO:0030534	2	0.022
cardiac muscle cell differentiation	GO:0055007	30	0.022
lipid storage	GO:0019915	1	0.021
response to chemical	GO:0042221	320	0.020
single organism organelle organization	GO:1902589	199	0.020
post embryonic organ development	GO:0048569	4	0.020
regulation of cardiac muscle contraction	GO:0055117	2	0.020
regulation of multicellular organismal process	GO:0051239	277	0.019
maintenance of location	GO:0051235	4	0.019
atp catabolic process	GO:0006200	4	0.019
heart process	GO:0003015	71	0.019
lymphoid lineage cell migration	GO:0097534	4	0.018
ventricular cardiac muscle tissue morphogenesis	GO:0055010	2	0.018
response to nutrient	GO:0007584	3	0.018
regulation of ion transmembrane transporter activity	GO:0032412	2	0.018
protein targeting to nucleus	GO:0044744	3	0.018
nucleocytoplasmic transport	GO:0006913	4	0.018
heart morphogenesis	GO:0003007	156	0.017
purine nucleoside monophosphate catabolic process	GO:0009128	4	0.017
regulation of reactive oxygen species metabolic process	GO:2000377	2	0.017
meiotic nuclear division	GO:0007126	4	0.017
cytoskeleton organization	GO:0007010	96	0.016
muscle system process	GO:0003012	20	0.016	Human
striated muscle cell development	GO:0055002	108	0.016
cardiac muscle cell development	GO:0055013	20	0.016
cellular protein catabolic process	GO:0044257	4	0.016
circulatory system process	GO:0003013	87	0.016
regulation of reproductive process	GO:2000241	4	0.016
embryonic organ development	GO:0048568	381	0.016
establishment of protein localization to organelle	GO:0072594	4	0.016
mitotic cytokinesis	GO:0000281	3	0.015
tube morphogenesis	GO:0035239	349	0.015
actin cytoskeleton organization	GO:0030036	63	0.015
cell motility	GO:0048870	244	0.015
protein import	GO:0017038	3	0.015
regulation of striated muscle contraction	GO:0006942	2	0.015
larval development	GO:0002164	2	0.014
muscle cell differentiation	GO:0042692	139	0.014
protein polymerization	GO:0051258	4	0.014
cytokinesis	GO:0000910	3	0.014
proteasomal protein catabolic process	GO:0010498	2	0.014
aging	GO:0007568	2	0.014
regulation of protein targeting	GO:1903533	2	0.013
heart looping	GO:0001947	94	0.013
cellular component assembly	GO:0022607	170	0.013
protein complex assembly	GO:0006461	30	0.013
regulation of heart contraction	GO:0008016	32	0.013
nitric oxide metabolic process	GO:0046209	2	0.013
determination of bilateral symmetry	GO:0009855	204	0.013
regulation of transmembrane transporter activity	GO:0022898	2	0.013
reactive oxygen species metabolic process	GO:0072593	6	0.013
protein localization to nucleus	GO:0034504	3	0.013
angiogenesis	GO:0001525	158	0.013
regulation of metal ion transport	GO:0010959	4	0.013
regulation of system process	GO:0044057	40	0.012
regulation of calcium ion transport	GO:0051924	2	0.012
nuclear import	GO:0051170	3	0.012
cardiac ventricle development	GO:0003231	9	0.012
response to carbohydrate	GO:0009743	3	0.012
regulation of cytoplasmic transport	GO:1903649	4	0.012
cytoskeleton dependent cytokinesis	GO:0061640	3	0.012
ventricular cardiac muscle tissue development	GO:0003229	3	0.012
proteolysis involved in cellular protein catabolic process	GO:0051603	3	0.012
signal transduction	GO:0007165	455	0.012
positive regulation of transport	GO:0051050	2	0.011
regionalization	GO:0003002	274	0.011
macromolecular complex disassembly	GO:0032984	1	0.011
regulation of anatomical structure morphogenesis	GO:0022603	130	0.011
inorganic ion transmembrane transport	GO:0098660	57	0.011
epithelial tube morphogenesis	GO:0060562	148	0.011
regulation of purine nucleotide catabolic process	GO:0033121	2	0.011
carboxylic acid metabolic process	GO:0019752	22	0.011
regulation of nitric oxide mediated signal transduction	GO:0010749	1	0.010
regulation of cell shape	GO:0008360	1	0.010
regulation of nucleotide catabolic process	GO:0030811	2	0.010
response to corticosteroid	GO:0031960	1	0.010

tnni2b.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease	DO term ID	Probability	Func Analog Org
muscle tissue disease	DOID:66	0.022	Human
intrinsic cardiomyopathy	DOID:0060036	0.022
cardiovascular system disease	DOID:1287	0.022
cardiomyopathy	DOID:0050700	0.022
disease of anatomical entity	DOID:7	0.022	Human
myopathy	DOID:423	0.022
muscular disease	DOID:0080000	0.022	Human
heart disease	DOID:114	0.022
musculoskeletal system disease	DOID:17	0.022	Human
hypertrophic cardiomyopathy	DOID:11984	0.018

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