Danio rerio

59 known processes

mdkb

midkine-related growth factor b

(Aliases: mdk,fj33b02,wu:fj48a12,wu:fb79b05,fj48a12,mdk2,fb79b05,plei2,cb518,wu:fj33b02)

mdkb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
head developmentGO:00603223030.852
astrocyte differentiationGO:004870810.836
central nervous system developmentGO:00074173870.813
brain developmentGO:00074202930.723
generation of neuronsGO:00486993850.706
neuron differentiationGO:00301823530.654
chordate embryonic developmentGO:00430092710.583
cell projection morphogenesisGO:00488582440.570
gene expressionGO:00104672520.545
Mouse
locomotory behaviorGO:0007626340.442
brain morphogenesisGO:0048854180.442
morphogenesis of an epitheliumGO:00020093330.382
Zebrafish
endodermal cell fate determinationGO:000749320.376
cellular macromolecule biosynthetic processGO:00346452240.323
Mouse
cellular nitrogen compound metabolic processGO:00346412900.320
Mouse
epithelial cell differentiationGO:00308551160.310
regulation of developmental processGO:00507932470.302
eye morphogenesisGO:00485921440.294
sensory organ developmentGO:00074233930.279
embryonic organ developmentGO:00485683810.256
cellular response to prostaglandin stimulusGO:007137930.246
response to prostaglandinGO:003469450.224
cell proliferation in hindbrainGO:002153440.223
regulation of multicellular organismal developmentGO:20000262230.215
pancreas developmentGO:0031016840.206
response to radiationGO:0009314510.186
signal transductionGO:00071654550.185
cellular component morphogenesisGO:00329893360.178
negative regulation of cellular processGO:00485232830.172
Mouse
central nervous system myelinationGO:002201020.170
adult behaviorGO:003053420.159
embryonic skeletal system developmentGO:0048706970.158
hindbrain developmentGO:0030902910.158
Mouse
negative regulation of cell communicationGO:0010648960.155
embryo development ending in birth or egg hatchingGO:00097922710.152
neural tube developmentGO:0021915620.148
Zebrafish
extracellular structure organizationGO:0043062270.139
response to woundingGO:00096111160.133
Mouse
maintenance of locationGO:005123540.133
cellular biosynthetic processGO:00442492860.130
Mouse
hormone secretionGO:004687920.129
cerebellar granular layer developmentGO:002168130.127
Mouse
forebrain anterior posterior pattern specificationGO:002179730.126
cellular nitrogen compound biosynthetic processGO:00442712180.119
Mouse
sensory organ morphogenesisGO:00905962000.117
heterocycle biosynthetic processGO:00181302150.111
Mouse
regulation of hormone secretionGO:004688320.105
larval developmentGO:000216420.104
cell proliferation in forebrainGO:002184630.100
regulation of neuron migrationGO:200122220.100
camera type eye morphogenesisGO:00485931080.098
single organism behaviorGO:0044708240.098
Mouse
regulation of apoptotic processGO:0042981980.095
Mouse
nucleobase containing compound metabolic processGO:00061392740.094
Mouse
neuroepithelial cell differentiationGO:0060563260.088
regulation of nucleobase containing compound metabolic processGO:00192192500.087
Mouse
peripheral nervous system neuron differentiationGO:0048934280.086
neuron projection developmentGO:00311751800.086
embryonic organ morphogenesisGO:00485622740.084
anterior commissure morphogenesisGO:002196030.081
rna biosynthetic processGO:00327741810.080
Mouse
response to chemicalGO:00422213200.077
skeletal system morphogenesisGO:00487051020.073
cell surface receptor signaling pathwayGO:00071663250.071
cellular response to fatty acidGO:007139830.070
agingGO:000756820.069
neural tube formationGO:0001841160.069
Zebrafish
anatomical structure arrangementGO:004853220.068
cellular response to stressGO:0033554620.067
axis elongation involved in somitogenesisGO:009024520.067
lipid storageGO:001991510.067
dopaminergic neuron differentiationGO:0071542140.066
hormone transportGO:000991420.066
blood vessel developmentGO:00015682460.064
positive regulation of neuron migrationGO:200122420.063
growthGO:00400071740.063
macromolecule biosynthetic processGO:00090592270.063
Mouse
regulation of biological qualityGO:00650082630.062
rna metabolic processGO:00160702190.061
Mouse
carbohydrate homeostasisGO:003350010.061
regulation of cellular metabolic processGO:00313233200.059
Mouse
positive regulation of transcription dna templatedGO:0045893570.059
Mouse
negative regulation of epithelial cell proliferationGO:005068010.058
response to biotic stimulusGO:0009607970.058
forebrain dorsal ventral pattern formationGO:002179810.058
metencephalon developmentGO:0022037270.058
Mouse
ectodermal placode morphogenesisGO:0071697320.057
intra s dna damage checkpointGO:003157310.057
embryonic skeletal system morphogenesisGO:0048704930.056
positive regulation of cytokine productionGO:000181920.056
axon developmentGO:00615641660.055
cellular homeostasisGO:0019725260.055
regulation of metabolic processGO:00192223590.054
Mouse
eye developmentGO:00016542770.054
camera type eye developmentGO:00430102220.053
retinal pigment epithelium developmentGO:000340680.053
response to stressGO:00069502630.053
Mouse
negative regulation of signalingGO:0023057960.052
negative regulation of biological processGO:00485193040.051
Mouse
regulation of cellular biosynthetic processGO:00313262450.051
Mouse
positive regulation of macromolecule metabolic processGO:0010604930.051
Mouse
posterior lateral line system developmentGO:0048915460.050
circadian regulation of gene expressionGO:003292280.050
regenerationGO:0031099910.049
taxisGO:00423301090.049
regulation of cytokine productionGO:000181730.048
melanocyte differentiationGO:0030318260.048
regulation of intracellular protein transportGO:003315730.048
peptide transportGO:001583310.048
epithelial cell developmentGO:0002064420.047
protein stabilizationGO:005082120.045
spermatid differentiationGO:004851520.045
neuron projection morphogenesisGO:00488121610.045
regulation of nitrogen compound metabolic processGO:00511712510.044
Mouse
positive regulation of developmental processGO:0051094500.044
post embryonic morphogenesisGO:000988640.044
heart developmentGO:00075073130.043
innervationGO:006038430.043
developmental pigmentationGO:0048066480.043
negative regulation of gliogenesisGO:001401410.043
nucleic acid metabolic processGO:00903042440.041
Mouse
forebrain regionalizationGO:002187140.041
cellular response to chemical stimulusGO:00708871570.041
retinal ganglion cell axon guidanceGO:0031290350.041
epibolyGO:0090504410.040
regulation of catalytic activityGO:0050790550.040
negative regulation of protein transportGO:005122430.039
forebrain developmentGO:0030900960.039
Mouse
wnt signaling pathwayGO:0016055800.038
positive regulation of transportGO:005105020.038
system processGO:00030081850.038
Mouse
negative regulation of multicellular organismal processGO:0051241690.038
otic vesicle morphogenesisGO:0071600340.038
regulation of multicellular organism growthGO:004001440.037
cellular macromolecule metabolic processGO:00442603910.037
Mouse
organic cyclic compound metabolic processGO:19013603010.036
Mouse
regulation of protein transportGO:005122330.036
retina development in camera type eyeGO:00600411460.036
regulation of establishment of protein localizationGO:007020140.035
determination of left right symmetryGO:00073681790.035
regulation of cell communicationGO:00106462320.034
blood vessel morphogenesisGO:00485142160.034
developmental growthGO:00485891660.034
regulation of cell differentiationGO:00455951420.034
neuromuscular processGO:005090570.033
regulation of response to stimulusGO:00485832690.033
Mouse
heart morphogenesisGO:00030071560.033
forebrain midbrain boundary formationGO:002190510.032
endodermal digestive tract morphogenesisGO:006103120.032
positive regulation of secretionGO:005104710.031
aromatic compound biosynthetic processGO:00194382170.031
Mouse
glucose homeostasisGO:004259310.031
behaviorGO:0007610740.031
Mouse
regulation of gene expressionGO:00104682650.030
Mouse
midbrain developmentGO:0030901280.030
cell part morphogenesisGO:00329902460.030
columnar cuboidal epithelial cell differentiationGO:0002065380.030
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.030
appendage developmentGO:0048736800.030
mononuclear cell proliferationGO:003294310.029
regulation of cell activationGO:005086510.029
epithelial tube morphogenesisGO:00605621480.029
Zebrafish
homeostatic processGO:00425921420.029
neuroblast proliferationGO:000740520.029
regulation of inner ear receptor cell differentiationGO:200098010.028
regulation of insulin like growth factor receptor signaling pathwayGO:004356710.028
response to endogenous stimulusGO:0009719830.028
anterior posterior pattern specificationGO:00099521520.027
retinoic acid receptor signaling pathwayGO:0048384160.027
negative regulation of cytokine productionGO:000181810.027
glial cell differentiationGO:0010001420.027
negative regulation of developmental processGO:0051093650.027
single organism transportGO:00447652060.027
intracellular signal transductionGO:0035556850.027
regulation of sequence specific dna binding transcription factor activityGO:005109090.026
organic substance biosynthetic processGO:19015762890.026
Mouse
cellular amine metabolic processGO:004410620.026
cellular response to lipidGO:0071396390.026
single organism metabolic processGO:00447102170.025
chemical homeostasisGO:0048878490.025
ectodermal placode formationGO:0060788260.024
response to external stimulusGO:00096052640.024
positive regulation of nitrogen compound metabolic processGO:0051173690.024
Mouse
transcription dna templatedGO:00063511810.024
Mouse
enzyme linked receptor protein signaling pathwayGO:00071671060.024
macromolecule modificationGO:00434121110.024
regulation of canonical wnt signaling pathwayGO:0060828340.024
water homeostasisGO:003010440.024
regulation of cellular protein metabolic processGO:0032268520.023
cell cycle g1 s phase transitionGO:004484310.023
regulation of protein modification by small protein conjugation or removalGO:190332030.023
cell proliferationGO:0008283800.023
chondrocyte developmentGO:000206340.023
startle responseGO:000196440.023
peripheral nervous system developmentGO:0007422550.023
regulation of glial cell differentiationGO:004568540.023
cell proliferation in midbrainGO:003327840.023
regulation of transcription involved in cell fate commitmentGO:006085010.023
organic substance transportGO:0071702580.023
ribose phosphate metabolic processGO:0019693270.023
regulation of nucleoside metabolic processGO:000911820.023
negative regulation of signal transductionGO:0009968940.023
regulation of molecular functionGO:0065009700.023
ectodermal placode developmentGO:0071696370.023
olfactory lobe developmentGO:002198840.022
hindbrain morphogenesisGO:0021575220.022
regulation of macromolecule biosynthetic processGO:00105562250.022
Mouse
regulation of rna metabolic processGO:00512522240.022
Mouse
rostrocaudal neural tube patterningGO:0021903290.022
abducens nucleus developmentGO:002174220.022
cell cell adhesion involved in gastrulationGO:007058640.022
negative regulation of cell deathGO:0060548600.021
Mouse
positive regulation of cell differentiationGO:0045597300.021
negative regulation of protein phosphorylationGO:000193340.021
cell morphogenesis involved in differentiationGO:00009041950.021
extracellular matrix organizationGO:0030198270.021
photoreceptor cell differentiationGO:0046530550.021
determination of heart left right asymmetryGO:00613711170.020
regulation of multicellular organismal processGO:00512392770.020
embryonic heart tube developmentGO:00350501330.020
multicellular organismal water homeostasisGO:005089110.020
regulation of transcription from rna polymerase ii promoterGO:00063571140.020
retinal cell programmed cell deathGO:004666620.020
regulation of cell cycleGO:0051726520.020
Zebrafish
response to vitaminGO:003327330.020
positive regulation of cell divisionGO:005178120.019
nucleocytoplasmic transportGO:000691340.019
regulation of syncytium formation by plasma membrane fusionGO:006014220.019
tube closureGO:006060610.019
regulation of gtp catabolic processGO:003312420.019
regulation of bindingGO:005109830.019
neural precursor cell proliferationGO:0061351200.019
digestive system developmentGO:00551232890.019
positive regulation of cell fate specificationGO:004266010.019
peripheral nervous system neuron axonogenesisGO:0048936130.019
gastrulationGO:00073692080.019
neuron deathGO:0070997210.019
Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.019
Mouse
negative regulation of wnt signaling pathwayGO:0030178300.018
regulation of cell deathGO:00109411030.018
Mouse
positive regulation of axon extension involved in axon guidanceGO:004884210.018
response to nutrientGO:000758430.018
regulation of eye photoreceptor cell developmentGO:004247820.018
negative regulation of map kinase activityGO:004340720.018
regulation of rna biosynthetic processGO:20011412130.018
Mouse
regulation of localizationGO:00328791040.017
intracellular receptor signaling pathwayGO:0030522300.017
negative regulation of programmed cell deathGO:0043069580.017
Mouse
protein targeting to nucleusGO:004474430.017
iris morphogenesisGO:006107210.017
cerebellum developmentGO:0021549170.017
Mouse
axonogenesis involved in innervationGO:006038510.017
pigmentationGO:0043473850.017
positive regulation of biological processGO:00485182530.017
ear developmentGO:00435831270.017
cellular response to organic substanceGO:00713101050.017
dendrite guidanceGO:007098300.017
regulation of wnt signaling pathwayGO:0030111530.017
positive regulation of tyrosine phosphorylation of stat3 proteinGO:004251710.017
regulation of cellular amine metabolic processGO:003323800.016
positive regulation of nucleic acid templated transcriptionGO:1903508570.016
Mouse
nucleobase containing compound biosynthetic processGO:00346542050.016
Mouse
extrinsic apoptotic signaling pathwayGO:009719130.016
glial cell developmentGO:0021782200.016
regulation of protein metabolic processGO:0051246560.016
mesenchymal cell developmentGO:0014031780.016
negative regulation of defense responseGO:003134820.016
determination of pancreatic left right asymmetryGO:0035469110.016
pigment cell differentiationGO:0050931380.016
response to carbohydrateGO:000974330.016
angiogenesisGO:00015251580.015
development of primary female sexual characteristicsGO:004654540.015
regulation of retinoic acid receptor signaling pathwayGO:004838550.015
cellular chemical homeostasisGO:0055082170.015
specification of symmetryGO:00097992040.015
response to hexoseGO:000974630.015
response to light stimulusGO:0009416460.015
protein phosphorylationGO:0006468470.015
positive regulation of embryonic developmentGO:004001930.014
cognitionGO:005089010.014
Mouse
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.014
positive regulation of metabolic processGO:00098931080.014
Mouse
stem cell differentiationGO:00488631170.014
positive regulation of secretion by cellGO:190353210.014
neuron developmentGO:00486662620.014
negative regulation of response to stimulusGO:00485851040.014
embryonic viscerocranium morphogenesisGO:0048703520.014
mesenchymal cell differentiationGO:0048762870.014
regulation of oligodendrocyte differentiationGO:004871310.014
nucleic acid templated transcriptionGO:00976591810.014
Mouse
regulation of cytoplasmic transportGO:190364940.014
response to inorganic substanceGO:0010035380.014
collateral sprouting in absence of injuryGO:004866940.013
regulation of nucleotide catabolic processGO:003081120.013
cellular response to dna damage stimulusGO:0006974240.013
response to metal ionGO:0010038340.013
heart loopingGO:0001947940.013
regulation of gtpase activityGO:004308720.013
skeletal system developmentGO:00015011810.013
phagocytosisGO:000690930.013
single organism intracellular transportGO:1902582250.013
canonical wnt signaling pathwayGO:0060070480.013
regulation of signalingGO:00230512350.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.013
Mouse
multicellular organism growthGO:003526440.013
response to oxygen containing compoundGO:1901700550.013
positive regulation of muscle tissue developmentGO:190186310.013
positive regulation of multicellular organismal processGO:0051240520.013
positive regulation of rna metabolic processGO:0051254590.013
Mouse
cell morphogenesisGO:00009022890.013
cellular component assemblyGO:00226071700.012
telencephalon developmentGO:0021537140.012
Mouse
carboxylic acid metabolic processGO:0019752220.012
negative regulation of mapk cascadeGO:004340940.012
regionalizationGO:00030022740.012
leukocyte proliferationGO:007066110.012
response to organic substanceGO:00100331530.012
posterior lateral line developmentGO:0048916380.012
transmission of nerve impulseGO:0019226190.012
regulation of transportGO:0051049450.012
protein secretionGO:000930610.012
establishment of localizationGO:00512342440.011
neuroblast differentiationGO:001401610.011
primitive hemopoiesisGO:0060215270.011
stem cell proliferationGO:007208940.011
regulation of biomineral tissue developmentGO:007016720.011
retina layer formationGO:0010842240.011
negative regulation of intracellular protein transportGO:009031730.011
ribonucleotide metabolic processGO:0009259270.011
proteasomal protein catabolic processGO:001049820.011
endocrine hormone secretionGO:006098620.011
regulation of programmed cell deathGO:00430671010.011
Mouse
cell morphogenesis involved in neuron differentiationGO:00486671630.011
mitotic cell cycle processGO:1903047480.011
positive regulation of epithelial cell differentiationGO:003085820.011
transportGO:00068102200.011
nuclear transportGO:005116940.010
oligodendrocyte differentiationGO:0048709230.010
trigeminal nerve developmentGO:002155930.010
regulation of cellular amino acid metabolic processGO:000652100.010
mammillary body developmentGO:002176740.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.010
oxoacid metabolic processGO:0043436310.010
regulation of inflammatory responseGO:005072720.010

mdkb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.025
disease of anatomical entityDOID:700.025
disease of cellular proliferationDOID:1456600.013
reproductive organ cancerDOID:19300.013
female reproductive organ cancerDOID:12000.013
cancerDOID:16200.013
organ system cancerDOID:005068600.013
congenital nervous system abnormalityDOID:249000.011
physical disorderDOID:008001500.011