Danio rerio

36 known processes

mdka

midkine-related growth factor

(Aliases: fb05b02,zgc:86655,wu:fc32h11,mdk1,plei1,wu:fb05b02)

mdka biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
morphogenesis of an epitheliumGO:00020093330.959
embryo development ending in birth or egg hatchingGO:00097922710.798
skeletal muscle organ developmentGO:0060538780.673
sensory organ developmentGO:00074233930.660
neuron differentiationGO:00301823530.449
Zebrafish
camera type eye developmentGO:00430102220.377
blood vessel morphogenesisGO:00485142160.353
axon ensheathmentGO:0008366180.351
blood vessel developmentGO:00015682460.292
transmission of nerve impulseGO:0019226190.285
astrocyte differentiationGO:004870810.282
eye developmentGO:00016542770.282
lens development in camera type eyeGO:0002088220.253
epithelial tube morphogenesisGO:00605621480.252
embryonic organ developmentGO:00485683810.250
neurological system processGO:0050877620.240
Mouse
chordate embryonic developmentGO:00430092710.223
actin cytoskeleton organizationGO:0030036630.214
determination of left right symmetryGO:00073681790.205
endochondral bone morphogenesisGO:006035080.185
system processGO:00030081850.182
Mouse
vasculature developmentGO:00019442780.180
epithelial tube formationGO:0072175190.180
somite developmentGO:0061053960.165
gene expressionGO:00104672520.162
Mouse
response to stressGO:00069502630.157
Mouse
digestive system developmentGO:00551232890.147
regulation of biological qualityGO:00650082630.145
detection of abiotic stimulusGO:0009582240.137
response to chemicalGO:00422213200.135
skeletal system developmentGO:00015011810.132
response to radiationGO:0009314510.129
determination of bilateral symmetryGO:00098552040.127
sprouting angiogenesisGO:0002040530.127
eye morphogenesisGO:00485921440.122
axon ensheathment in central nervous systemGO:003229120.118
regulation of metabolic processGO:00192223590.113
Mouse
neuron projection developmentGO:00311751800.106
embryonic cranial skeleton morphogenesisGO:0048701900.096
response to vitaminGO:003327330.093
glial cell migrationGO:000834730.093
generation of neuronsGO:00486993850.091
Zebrafish
specification of symmetryGO:00097992040.091
organelle assemblyGO:00709251100.086
regulation of signalingGO:00230512350.084
regulation of locomotionGO:0040012550.084
cellular component assemblyGO:00226071700.084
action potentialGO:0001508190.081
extracellular matrix organizationGO:0030198270.079
regulation of membrane potentialGO:0042391230.079
striated muscle cell developmentGO:00550021080.078
myelinationGO:0042552180.078
epibolyGO:0090504410.078
central nervous system myelinationGO:002201020.073
small molecule metabolic processGO:0044281770.073
neural tube developmentGO:0021915620.072
digestive tract developmentGO:00485652650.067
glial cell proliferationGO:001400940.067
glial cell developmentGO:0021782200.066
response to carbohydrateGO:000974330.065
ensheathment of neuronsGO:0007272180.065
positive regulation of response to stimulusGO:0048584800.065
positive regulation of biological processGO:00485182530.064
Zebrafish Mouse
multicellular organismal signalingGO:0035637220.064
cellular component biogenesisGO:00440851780.064
cellular nitrogen compound metabolic processGO:00346412900.063
Mouse
camera type eye morphogenesisGO:00485931080.063
regulation of cell migrationGO:0030334400.063
tube morphogenesisGO:00352393490.061
nucleobase containing compound metabolic processGO:00061392740.061
Mouse
muscle structure developmentGO:00610611960.060
positive regulation of cell cycleGO:004578730.060
neuron projection morphogenesisGO:00488121610.057
neuron developmentGO:00486662620.052
carboxylic acid metabolic processGO:0019752220.051
locomotionGO:00400113130.051
muscle cell developmentGO:00550011150.051
mitochondrion organizationGO:000700540.050
neuroblast proliferationGO:000740520.050
actomyosin structure organizationGO:0031032530.050
embryonic organ morphogenesisGO:00485622740.049
proteolysis involved in cellular protein catabolic processGO:005160330.049
adherens junction organizationGO:003433240.048
regulation of macromolecule metabolic processGO:00602553170.048
Mouse
regulation of multicellular organismal developmentGO:20000262230.047
Zebrafish
extracellular structure organizationGO:0043062270.047
epithelial cell developmentGO:0002064420.047
regulation of primary metabolic processGO:00800903110.044
Mouse
cell proliferationGO:0008283800.043
response to glucoseGO:000974930.043
cell substrate adhesionGO:003158940.043
negative regulation of epithelial cell migrationGO:001063310.042
cellular component movementGO:00069283350.041
regulation of rna metabolic processGO:00512522240.040
Mouse
regulation of protein modification by small protein conjugation or removalGO:190332030.040
cell projection assemblyGO:0030031640.039
regulation of cell developmentGO:00602841000.039
Zebrafish
sensory organ morphogenesisGO:00905962000.039
regulation of cell projection assemblyGO:006049140.039
retina morphogenesis in camera type eyeGO:0060042790.038
signal transductionGO:00071654550.037
single organism metabolic processGO:00447102170.037
negative regulation of endothelial cell migrationGO:001059610.036
regulation of cellular amine metabolic processGO:003323800.036
modification dependent macromolecule catabolic processGO:004363230.036
neuronal action potentialGO:0019228180.035
macromolecule modificationGO:00434121110.034
response to nutrientGO:000758430.033
positive regulation of glial cell proliferationGO:006025210.033
negative regulation of metabolic processGO:0009892860.033
establishment or maintenance of cell polarityGO:0007163290.032
gliogenesisGO:0042063450.032
mitotic nuclear divisionGO:0007067180.032
morphogenesis of embryonic epitheliumGO:0016331300.032
negative regulation of cellular component organizationGO:0051129160.032
skeletal system morphogenesisGO:00487051020.031
regulation of localizationGO:00328791040.031
glial cell differentiationGO:0010001420.031
negative regulation of cellular processGO:00485232830.031
Mouse
beta amyloid metabolic processGO:005043510.031
positive regulation of multicellular organismal processGO:0051240520.030
Zebrafish
response to monosaccharideGO:003428430.030
response to oxygen containing compoundGO:1901700550.030
regulation of response to stimulusGO:00485832690.030
Mouse
striated muscle cell differentiationGO:00511461290.030
amine metabolic processGO:000930820.029
positive regulation of cellular processGO:00485222010.029
Zebrafish Mouse
nitrogen compound metabolic processGO:00068073190.029
Mouse
angiogenesisGO:00015251580.029
growthGO:00400071740.029
oligodendrocyte developmentGO:001400370.029
cellular macromolecule metabolic processGO:00442603910.028
Mouse
regulation of cellular component organizationGO:0051128860.028
detection of stimulusGO:0051606290.028
fin morphogenesisGO:0033334530.028
regulation of developmental processGO:00507932470.028
Zebrafish
negative regulation of developmental processGO:0051093650.028
wnt signaling pathwayGO:0016055800.027
negative regulation of biological processGO:00485193040.027
Mouse
bmp signaling pathwayGO:0030509520.027
lateral line system developmentGO:0048925760.027
peptidyl serine modificationGO:001820920.027
regulation of canonical wnt signaling pathwayGO:0060828340.027
positive regulation of cellular metabolic processGO:0031325940.027
Mouse
regulation of blood vessel endothelial cell migrationGO:004353550.026
peptidyl serine phosphorylationGO:001810510.025
response to hexoseGO:000974630.025
cell morphogenesisGO:00009022890.025
Zebrafish
single organism organelle organizationGO:19025891990.025
regulation of cytokine productionGO:000181730.025
sex determinationGO:000753010.025
regulation of wnt signaling pathwayGO:0030111530.025
regulation of peptidyl tyrosine phosphorylationGO:005073010.025
tube formationGO:0035148250.025
cell projection organizationGO:00300302840.024
axon developmentGO:00615641660.024
embryonic skeletal joint morphogenesisGO:006027230.024
cell migrationGO:00164772370.024
muscle cell differentiationGO:00426921390.024
response to external stimulusGO:00096052640.024
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.023
cellular amine metabolic processGO:004410620.023
regulation of cell activationGO:005086510.023
regulation of nucleobase containing compound metabolic processGO:00192192500.023
Mouse
actin filament based processGO:0030029640.023
axon guidanceGO:0007411860.022
organonitrogen compound metabolic processGO:1901564740.022
carbon dioxide transmembrane transportGO:003537810.022
regulation of nitrogen compound metabolic processGO:00511712510.022
Mouse
regulation of cellular metabolic processGO:00313233200.021
Mouse
oxoacid metabolic processGO:0043436310.021
cellular component assembly involved in morphogenesisGO:00109271070.021
taxisGO:00423301090.021
chemotaxisGO:00069351040.021
regulation of nervous system developmentGO:0051960900.021
Zebrafish
regulation of cgmp biosynthetic processGO:003082660.021
negative regulation of secretion by cellGO:190353120.021
protein modification processGO:00362111000.021
muscle tissue developmentGO:00605371100.021
regulation of multicellular organismal processGO:00512392770.021
Zebrafish
amyloid precursor protein catabolic processGO:004298710.021
stem cell differentiationGO:00488631170.021
Zebrafish
regulation of wound healingGO:006104120.021
localization of cellGO:00516742440.021
negative regulation of cellular metabolic processGO:0031324770.021
endodermal cell fate determinationGO:000749320.020
negative regulation of cell migrationGO:0030336170.020
determination of heart left right asymmetryGO:00613711170.020
ubiquitin dependent protein catabolic processGO:000651130.020
cellular protein catabolic processGO:004425740.020
cell motilityGO:00488702440.020
cell surface receptor signaling pathwayGO:00071663250.019
cell part morphogenesisGO:00329902460.019
cell growthGO:0016049570.019
somitogenesisGO:0001756870.019
regulation of rho protein signal transductionGO:003502320.019
axonogenesisGO:00074091520.019
muscle organ developmentGO:00075171010.019
meiotic nuclear divisionGO:000712640.019
negative regulation of locomotionGO:0040013180.019
visual perceptionGO:0007601170.019
wound healingGO:0042060900.018
regulation of protein localization to nucleusGO:190018020.018
positive regulation of secretion by cellGO:190353210.018
positive regulation of transportGO:005105020.018
lipid metabolic processGO:0006629520.018
cellular response to chemical stimulusGO:00708871570.018
regulation of myotube differentiationGO:001083020.018
cellular amino acid metabolic processGO:000652070.018
regulation of jak stat cascadeGO:004642530.018
spermatid developmentGO:000728620.018
negative regulation of signal transductionGO:0009968940.018
neutrophil homeostasisGO:000178010.018
heart loopingGO:0001947940.017
appendage developmentGO:0048736800.017
water homeostasisGO:003010440.017
cellular component morphogenesisGO:00329893360.017
Zebrafish
regulation of transcription from rna polymerase iii promoterGO:000635910.017
protein secretionGO:000930610.017
developmental growthGO:00485891660.017
regulation of cellular component movementGO:0051270550.017
positive regulation of developmental processGO:0051094500.017
Zebrafish
stem cell proliferationGO:007208940.017
regulation of filopodium assemblyGO:005148920.017
bone developmentGO:0060348140.017
regulation of gene expressionGO:00104682650.017
Mouse
epithelial cell differentiationGO:00308551160.017
cellular ketone metabolic processGO:0042180110.016
regulation of multicellular organism growthGO:004001440.016
positive regulation of cell activationGO:005086710.016
modification dependent protein catabolic processGO:001994130.016
regulation of neural precursor cell proliferationGO:200017730.016
negative regulation of cell communicationGO:0010648960.016
response to light stimulusGO:0009416460.016
gastrulationGO:00073692080.016
organelle organizationGO:00069962270.016
positive regulation of cell adhesionGO:004578510.016
response to woundingGO:00096111160.015
Mouse
blood circulationGO:0008015870.015
gtp metabolic processGO:004603940.015
calcium ion dependent exocytosisGO:001715610.015
regionalizationGO:00030022740.015
negative regulation of multicellular organismal processGO:0051241690.015
liver developmentGO:0001889960.015
neuron projection guidanceGO:0097485860.015
cellular component maintenanceGO:004395430.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
Mouse
head developmentGO:00603223030.014
Zebrafish Mouse
positive regulation of cellular amine metabolic processGO:003324000.014
biological adhesionGO:0022610400.014
mitotic dna integrity checkpointGO:004477440.014
organic acid metabolic processGO:0006082310.014
morphogenesis of an epithelial sheetGO:0002011490.014
lymph vessel developmentGO:0001945270.014
olfactory lobe developmentGO:002198840.014
nucleic acid metabolic processGO:00903042440.014
Mouse
regulation of cellular amino acid metabolic processGO:000652100.014
negative regulation of macromolecule metabolic processGO:0010605760.014
negative regulation of signalingGO:0023057960.014
protein metabolic processGO:00195381830.014
cellular protein metabolic processGO:00442671290.014
response to abiotic stimulusGO:00096281220.014
regenerationGO:0031099910.014
polarized epithelial cell differentiationGO:003085940.014
venous blood vessel morphogenesisGO:004884530.014
regulation of glial cell proliferationGO:006025140.013
regulation of neuron differentiationGO:0045664560.013
Zebrafish
ear developmentGO:00435831270.013
neural tube formationGO:0001841160.013
response to endogenous stimulusGO:0009719830.013
embryonic skeletal system morphogenesisGO:0048704930.013
pigmentationGO:0043473850.013
neuronal stem cell maintenanceGO:009715020.013
spermatid differentiationGO:004851520.013
epiboly involved in gastrulation with mouth forming secondGO:0055113350.013
organic substance biosynthetic processGO:19015762890.013
Mouse
lymphatic endothelial cell differentiationGO:006083610.013
photoreceptor cell differentiationGO:0046530550.013
positive regulation of metabolic processGO:00098931080.013
Mouse
cellular biosynthetic processGO:00442492860.013
Mouse
proteasomal protein catabolic processGO:001049820.013
regulation of cell matrix adhesionGO:000195210.013
regulation of cytoplasmic transportGO:190364940.013
positive regulation of cell developmentGO:0010720250.013
Zebrafish
primary neural tube formationGO:001402010.013
positive regulation of gliogenesisGO:001401520.013
tissue regenerationGO:0042246740.012
organic cyclic compound biosynthetic processGO:19013622230.012
Mouse
cytoskeleton organizationGO:0007010960.012
cell adhesionGO:0007155400.012
regulation of establishment of protein localizationGO:007020140.012
positive regulation of secretionGO:005104710.012
cellular protein modification processGO:00064641000.012
i kappab kinase nf kappab signalingGO:000724940.012
positive regulation of locomotionGO:0040017140.012
bone morphogenesisGO:0060349110.012
positive regulation of immune effector processGO:000269930.012
biosynthetic processGO:00090582940.012
Mouse
regulation of cellular ketone metabolic processGO:001056570.012
small gtpase mediated signal transductionGO:000726480.012
protein localization to plasma membraneGO:007265910.012
positive regulation of stem cell proliferationGO:200064810.012
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.012
positive regulation of cellular catabolic processGO:003133130.012
post embryonic organ developmentGO:004856940.012
embryonic camera type eye developmentGO:0031076290.012
tube closureGO:006060610.011
pronephros developmentGO:0048793690.011
hypochord developmentGO:005501630.011
positive regulation of neurogenesisGO:0050769240.011
Zebrafish
appendage morphogenesisGO:0035107560.011
fin developmentGO:0033333770.011
regulation of signal transductionGO:00099662250.011
regulation of anatomical structure morphogenesisGO:00226031300.011
maintenance of locationGO:005123540.011
immune system processGO:00023762410.011
negative regulation of gastrulationGO:2000542110.011
cell projection morphogenesisGO:00488582440.011
protein localizationGO:0008104400.011
lymphoid lineage cell migration into thymusGO:009753540.011
negative regulation of gliogenesisGO:001401410.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
embryonic skeletal joint developmentGO:007249830.011
regulation of neurogenesisGO:0050767870.011
Zebrafish
organ regenerationGO:003110010.011
cranial nerve developmentGO:0021545420.011
cytokinesisGO:000091030.011
negative regulation of histone modificationGO:003105710.010
neuron migrationGO:0001764220.010
positive regulation of striated muscle tissue developmentGO:004584410.010
cell junction maintenanceGO:003433120.010
positive regulation of protein kinase b signalingGO:005189710.010
hepaticobiliary system developmentGO:0061008980.010
exocrine system developmentGO:0035272280.010
mesoderm morphogenesisGO:0048332510.010

mdka disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.041
musculoskeletal system diseaseDOID:1700.041
disease of anatomical entityDOID:700.041
bone development diseaseDOID:008000600.025
bone diseaseDOID:008000100.025
dysostosisDOID:193400.019
nervous system diseaseDOID:86300.018
cardiovascular system diseaseDOID:128700.014